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Global Positioning System (GPS) Exposure to Environments & Relations With Biomarkers of Cancer Risk

2019年6月17日 更新者:Marta Jankowska、University of California, San Diego
The prevalence of overweight and obesity are increasing worldwide. In the U.S., approximately 85,000 new cancer cases per year are related to obesity. Understanding lifestyle behaviors, their causes, and relations to cancer are critical. Where people spend their time during the day may be related to their risk of getting cancer. This project will assess behaviors in different locations across the day and relate exposure to different environments to biological outcomes.

研究概览

地位

完全的

详细说明

The purpose of this study is to advance methods of cancer risk exposure assessment by measuring both neighborhood access and total environment exposure to healthy environments by dynamically integrating Global Positioning System (GPS) data with Geographical Information System (GIS) data. We hypothesize that dynamic GPS based measures of environmental exposure will be more strongly related to behavior and insulin and inflammation biomarkers than static address based GIS measures of access.

Primary Aim:

To compare Dynamic vs Static GIS measures of physical activity (PA) supportivity and their associations with PA behaviors, body mass index (BMI), and biological markers.

Secondary Aim:

To compare Dynamic vs Static GIS measures of access to healthy food and their associations with dietary intake, BMI, and biological markers.

Exploratory aim:

Social environment (e.g. eating with others) has been identified as an important determinant of health, but assessment of this has been limited to self-report through surveys or text prompts. Images from a person worn camera (the SenseCam) provide an objective and continuous assessment of social environment e.g. number of social interactions per day, eating alone or with others. In a subsample of participants (N=30), we propose to explore whether portable SenseCam measures of social interactions & social behaviors from person view images are more strongly related to breast and colon cancer risk factors than self-reported social environment measures. Behaviors and built environments (especially food locations) can also be coded to validate the accuracy of the GIS measures and the machine learned behavior categories employed in the full sample.

研究类型

观察性的

注册 (实际的)

601

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • California
      • La Jolla、California、美国、92093
        • UC San Diego

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

35年 至 80年 (成人、年长者)

接受健康志愿者

是的

有资格学习的性别

全部

取样方法

非概率样本

研究人群

700 35 - 80 year old adults living in San Diego County

描述

Inclusion Criteria:

  • 35 - 80 years
  • live in the same residence selected for the study for at least one year
  • are able to walk without human assistance
  • are able to read and write fluently in English or Spanish
  • have a stable phone
  • leave their home at least 3 or more times per week
  • have a stable weight over the past 3 months (+/- 5 lbs)
  • spend most of their time within San Diego County
  • will be in San Diego County for the study period (i.e. not travel or border crossing)
  • are able to give informed consent and comply with the protocol
  • are willing to complete all assessments and wear all devices for 14 days.

Exclusion Criteria:

  • are younger than 435 or older than 80 years of age
  • are pregnant or nursing
  • have a mental state that would preclude complete understanding of the protocol or compliance
  • have a chronic illness that may be associated with weight change
  • are participating in another clinical trial
  • have type 1 diabetes
  • have an autoimmune disorder such as lupus, rheumatoid arthritis, or multiple sclerosis
  • have an intestinal disease such as celiac disease, Crohn's disease, or inflammatory bowel disease (IBD) or sensitivities or allergies to gluten
  • have psoriasis
  • have a history of or a current eating disorder
  • have had previous weight loss surgery
  • plan to travel into Mexico during the two-week study period or have a history of travel to Mexico
  • are taking second generation or "atypical" antipsychotics
  • live with someone else who is participating in this study
  • are currently taking weight loss supplements and unwilling to stop for a predetermined "wash-out" period

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

研究衡量的是什么?

主要结果指标

结果测量
大体时间
Blood Insulin Levels
大体时间:14 Days
14 Days

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Jacqueline Kerr, PhD、UC San Diego

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2014年7月1日

初级完成 (实际的)

2017年9月29日

研究完成 (实际的)

2017年9月29日

研究注册日期

首次提交

2014年3月13日

首先提交符合 QC 标准的

2014年3月19日

首次发布 (估计)

2014年3月21日

研究记录更新

最后更新发布 (实际的)

2019年6月19日

上次提交的符合 QC 标准的更新

2019年6月17日

最后验证

2019年6月1日

更多信息

与本研究相关的术语

其他研究编号

  • 1R01CA179977 (美国 NIH 拨款/合同)

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

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