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Assessing the Effectiveness of a Pharmacist-delivered Smoking Cessation Program in the State of Qatar

2017年6月1日 更新者:Dr. Maguy El Hajj、Qatar University
Thirty seven percent of adult male population smoke cigarettes in Qatar. The Global Youth Tobacco Survey also stated that 13.4% of male school students aged 13 to 15 years in Qatar smoke cigarettes. Smoking cessation is a key to reducing smoking related diseases and deaths. Health care providers are in an ideal position to encourage smoking cessation. Pharmacists are the most accessible health care providers and are uniquely situated to initiate behavior change among patients. Many western studies have shown that pharmacists can be successful in helping patients quit smoking. Studies demonstrating the effectiveness of pharmacist delivered smoking cessation programs are lacking in Qatar. This proposal aims to test the effect of a structured smoking cessation program delivered by trained ambulatory pharmacists in Qatar. A prospective, randomized, controlled trial will be conducted at 8 ambulatory pharmacies in Qatar. Participants will be randomly assigned to receive a 4-session face-to-face structured patient-specific smoking cessation program conducted by the pharmacist or 5 to 10 minutes of unstructured brief smoking cessation advice given by the pharmacist. Both groups will be offered nicotine therapy if feasible. The primary outcome of smoking cessation will be confirmed by exhaled carbon monoxide test at 12 months. If proven to be effective, this smoking cessation program will be considered as a model that Qatar and the region can apply to decrease smoking burden.

研究概览

研究类型

介入性

注册 (实际的)

314

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

      • Doha、卡塔尔
        • Primary Health Corporation (PHC) pharmacies
      • Doha、卡塔尔
        • Qatar Petroleum pharmacies

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

18年 及以上 (成人、年长者)

接受健康志愿者

不

有资格学习的性别

全部

描述

Eligible participants are:

  • patients aged 18 years and older who currently smoke one or more cigarettes daily for 7 days, are motivated to quit i.e.: in the preparation stage of the stage-of-change model, able to communicate in Arabic or English and are willing and capable of attending the scheduled sessions at the study pharmacies.

Exclusion criteria are:

  • use of other nicotine or tobacco products
  • current use or use in the last 30 days of quit smoking aids or medications
  • plan to leave Qatar in the next 12 months
  • presence of any major medical condition that would prevent use of the nicotine replacement therapy including hypersensitivity to the products, history of or recent myocardial infarction, life-threatening arrhythmias, severe or worsening angina, uncontrolled hypertension and temporomandibular joint disease (in case of nicotine gum)
  • pregnancy
  • psychiatric illness or other debilitating condition that would interfere with participation in the study.

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:双倍的

武器和干预

参与者组/臂
干预/治疗
有源比较器:Control arm
Participants in the control group will receive 5-10 minutes of unstructured brief smoking cessation advice by the pharmacist. In addition they will be provided with educational materials about smoking cessation and will be offered nicotine replacement therapy (NRT).
Participants in the control group will receive 5-10 minutes of unstructured brief smoking cessation advice by the pharmacist. In addition they will be provided with educational materials about smoking cessation and will be offered nicotine replacement therapy (NRT).
实验性的:Intervention arm
Participants assigned to the intervention arm will participate in a face-to-face 4-session program at the pharmacy delivered by the study pharmacist at 2-4-week intervals over 8 weeks in addition to nicotine replacement therapy. The sessions will be set at a date and time that is convenient for both the pharmacist and the participant. The pharmacist will deliver the program at a time different from his or her pharmacy duty regular time.

The first session will be time-intensive taking around 30 minutes. In this session, the study pharmacist will facilitate the participant's preparation to quit. The participant will select a quit date within the next 2-4 weeks. The pharmacist will discuss with the participant the benefits of smoking cessation and will provide him or her with tailored behavioral and lifestyle strategies.

To prevent nicotine withdrawal symptoms, the participant will be offered nicotine replacement therapy (NRT) The first follow-up session will be scheduled after 1 week of the participant's quit day and will take around 20 minutes. In this session, the pharmacist will determine the participant's smoking status and assess the NRT tolerability.

• If the participant fails to quit smoking, the pharmacist will carefully review the participant's experience during the attempt to quit and will work through the identified problems

其他名称:
  • Participants will participate in a face-to-face 4-session program at the pharmacy delivered by the study pharmacist at 2-4-week intervals over 8 weeks.

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Self-reported 7-day Point Prevalence Abstinence
大体时间:3 months
Self-reported 7-day point prevalence abstinence, defined as having smoked no cigarettes for the previous 7 days
3 months
Self-reported 30 Day Smoking Abstinence
大体时间:3 months
Self-reported 30-day point prevalence abstinence defined as having smoked no cigarettes in the last 30 days
3 months
Self-reported Continuous Abstinence at 3 Months
大体时间:3 months
Self-reported continuous abstinence defined as having smoked no cigarettes since quit day
3 months
Self-reported 7-day Point Prevalence Abstinence
大体时间:6 months
Defined as having smoked no cigarettes for the previous 7 days
6 months
Self-reported 30-day Point Prevalence Abstinence
大体时间:6 months
Defined as having smoked no cigarettes in the last 30 days
6 months
Self-reported Continuous Abstinence
大体时间:6 months
Defined as having smoked no cigarettes since quit day
6 months
Self-reported 7-day Point Prevalence Abstinence
大体时间:12 months
Defined as having smoked no cigarettes for the previous 7 days
12 months
Self-reported 30-day Point Prevalence Abstinence
大体时间:12 months
Defined as having smoked no cigarettes in the last 30 days
12 months
Self-reported Continuous Abstinence
大体时间:12 months
Defined as having smoked no cigarettes since quit day at 12 months
12 months
Objective Smoking Abstinence
大体时间:12 months
Smoking abstinence as objectively verified by the CO exhaled test at 12 months
12 months

次要结果测量

结果测量
措施说明
大体时间
Health Related Quality of Life
大体时间:6 month
Mean change in health related quality of life score from baseline to 6 months for quitters vs. non quitters
6 month

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Maguy S El Hajj, PharmD、Qatar University

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2013年2月1日

初级完成 (实际的)

2015年12月1日

研究完成 (实际的)

2016年6月1日

研究注册日期

首次提交

2014年4月20日

首先提交符合 QC 标准的

2014年4月24日

首次发布 (估计)

2014年4月25日

研究记录更新

最后更新发布 (实际的)

2018年1月2日

上次提交的符合 QC 标准的更新

2017年6月1日

最后验证

2017年6月1日

更多信息

与本研究相关的术语

其他研究编号

  • NPRP 4 - 716 - 3 - 203

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

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