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Effect of Low-level Laser Therapy on Exercise-induced Muscle Damage

2015年10月13日 更新者:Bruno Manfredini Baroni、Federal University of Health Science of Porto Alegre

Effect of Low-level Laser Therapy on Exercise-induced Muscle Damage: a Randomized Clinical Trial

Introduction: The effects of Low Level Laser Therapy (LLLT) on exercise-induced muscular damage have been studied over the last years. Studies have been conducted on animals and humans in order to try to show the benefits of the intervention, but there is still conflicting evidence about its protective and therapeutic effects.

Objectives: To describe the effects of LLLT on pain, strength and muscular inflammation after plyometric exercise.

Methods: A randomized, double-blinded, placebo-controlled trial with participation of 20 male healthy volunteers will be performed. Healthy and physically active individuals, aged between 18 and 35 years, with no history of injury on the lower limbs or contra-indications to maximal exercise performance will be included. A protocol of 10 series with 10 repetitions of the countermovement jump will be used to induce muscle damage at the lower limbs. Immediately before or after the exercise protocol, LLLT will be applied on one lower limb, while the other will receive placebo treatment. Phototherapy will be applied with an equipment of 810nm and a cluster with 5 diodes on 8 different points of the knee extensor muscle, totalizing a dosage of 240J. The placebo treatment will be held on the same way, but the equipment will be turned off. The volunteers will be evaluated at baseline (before the exercise protocol) and at follow-up of 24, 48 and 72 hours. The following outcomes will be evaluated: knee extensors isometric peak torque by Isokinetic Dynamometer, pain by Visual Analogue Scale and muscular tissue echo intensity by Ultrasonography.

研究概览

研究类型

介入性

注册 (实际的)

12

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • RS
      • Porto Alegre、RS、巴西、90050-170
        • Federal University of Health Science of Porto Alegre

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

18年 至 35年 (成人)

接受健康志愿者

是的

有资格学习的性别

男性

描述

Inclusion Criteria:

  • Healthy males aged between 18 and 35 years;
  • Sedentary or physically active individuals who exercise up to 3 times per week.

Exclusion Criteria:

  • Individuals who participate in systematic exercise training;
  • Individuals who participate in strength training for the lower limbs;
  • Individuals with lower or upper limb injuries;
  • Individuals with contra-indications to maximal exercise performance (due to neurological, cardiovascular or respiratory conditions);
  • Individuals who show difficulties to understand the study protocol.

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:双倍的

武器和干预

参与者组/臂
干预/治疗
实验性的:LLLT before muscle damage
Low Level Laser Therapy (LLLT) will be applied before the exercise protocol on one lower limb, while the other will receive placebo treatment. Phototherapy will be applied with an equipment of 810nm and a cluster with five diodes on eight different points of quadriceps muscle, totalizing a dosage of 240J.
安慰剂比较:Placebo LLLT before muscle damage
Placebo LLLT will be applied before the exercise protocol on one lower limb, while the other will receive real treatment. Placebo treatment will also be applied on eight different points of quadriceps muscle, but the equipment will be turned off.
有源比较器:LLLT after muscle damage
Low Level Laser Therapy (LLLT) will be applied after the exercise protocol on one lower limb, while the other will receive placebo treatment. Phototherapy will be applied with an equipment of 810nm and a cluster with five diodes on eight different points of quadriceps muscle, totalizing a dosage of 240J.
安慰剂比较:Placebo LLLT after muscle damage
Placebo LLLT will be applied after the exercise protocol on one lower limb, while the other will receive real treatment. Placebo treatment will also be applied on eight different points of quadriceps muscle, but the equipment will be turned off.

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Knee extensors isometric peak torque (Nm)
大体时间:Baseline and 24, 48 and 72 hours follow-up
Isokinetic Dynamometer
Baseline and 24, 48 and 72 hours follow-up

次要结果测量

结果测量
大体时间
Knee extensors soreness (Visual Analogue scale)
大体时间:Baseline and 24, 48 and 72 hours follow-up
Baseline and 24, 48 and 72 hours follow-up
Knee extensors echo intensity (number of white and black pixels)
大体时间:Baseline and 24, 48 and 72 hours follow-up
Baseline and 24, 48 and 72 hours follow-up

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 研究主任:Bruno Baroni, phD、Federal University of Health Science of Porto Alegre

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始

2015年6月1日

初级完成 (实际的)

2015年8月1日

研究完成 (实际的)

2015年9月1日

研究注册日期

首次提交

2015年7月7日

首先提交符合 QC 标准的

2015年7月8日

首次发布 (估计)

2015年7月9日

研究记录更新

最后更新发布 (估计)

2015年10月15日

上次提交的符合 QC 标准的更新

2015年10月13日

最后验证

2015年7月1日

更多信息

与本研究相关的术语

其他研究编号

  • 38076514.0.0000.5345

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

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