Effect of Low-level Laser Therapy on Exercise-induced Muscle Damage
Effect of Low-level Laser Therapy on Exercise-induced Muscle Damage: a Randomized Clinical Trial
Introduction: The effects of Low Level Laser Therapy (LLLT) on exercise-induced muscular damage have been studied over the last years. Studies have been conducted on animals and humans in order to try to show the benefits of the intervention, but there is still conflicting evidence about its protective and therapeutic effects.
Objectives: To describe the effects of LLLT on pain, strength and muscular inflammation after plyometric exercise.
Methods: A randomized, double-blinded, placebo-controlled trial with participation of 20 male healthy volunteers will be performed. Healthy and physically active individuals, aged between 18 and 35 years, with no history of injury on the lower limbs or contra-indications to maximal exercise performance will be included. A protocol of 10 series with 10 repetitions of the countermovement jump will be used to induce muscle damage at the lower limbs. Immediately before or after the exercise protocol, LLLT will be applied on one lower limb, while the other will receive placebo treatment. Phototherapy will be applied with an equipment of 810nm and a cluster with 5 diodes on 8 different points of the knee extensor muscle, totalizing a dosage of 240J. The placebo treatment will be held on the same way, but the equipment will be turned off. The volunteers will be evaluated at baseline (before the exercise protocol) and at follow-up of 24, 48 and 72 hours. The following outcomes will be evaluated: knee extensors isometric peak torque by Isokinetic Dynamometer, pain by Visual Analogue Scale and muscular tissue echo intensity by Ultrasonography.
Descripción general del estudio
Estado
Condiciones
Tipo de estudio
Inscripción (Actual)
Fase
- No aplica
Contactos y Ubicaciones
Ubicaciones de estudio
-
-
RS
-
Porto Alegre, RS, Brasil, 90050-170
- Federal University of Health Science of Porto Alegre
-
-
Criterios de participación
Criterio de elegibilidad
Edades elegibles para estudiar
Acepta Voluntarios Saludables
Géneros elegibles para el estudio
Descripción
Inclusion Criteria:
- Healthy males aged between 18 and 35 years;
- Sedentary or physically active individuals who exercise up to 3 times per week.
Exclusion Criteria:
- Individuals who participate in systematic exercise training;
- Individuals who participate in strength training for the lower limbs;
- Individuals with lower or upper limb injuries;
- Individuals with contra-indications to maximal exercise performance (due to neurological, cardiovascular or respiratory conditions);
- Individuals who show difficulties to understand the study protocol.
Plan de estudios
¿Cómo está diseñado el estudio?
Detalles de diseño
- Propósito principal: Tratamiento
- Asignación: Aleatorizado
- Modelo Intervencionista: Asignación paralela
- Enmascaramiento: Doble
Armas e Intervenciones
Grupo de participantes/brazo |
Intervención / Tratamiento |
|---|---|
|
Experimental: LLLT before muscle damage
Low Level Laser Therapy (LLLT) will be applied before the exercise protocol on one lower limb, while the other will receive placebo treatment.
Phototherapy will be applied with an equipment of 810nm and a cluster with five diodes on eight different points of quadriceps muscle, totalizing a dosage of 240J.
|
|
|
Comparador de placebos: Placebo LLLT before muscle damage
Placebo LLLT will be applied before the exercise protocol on one lower limb, while the other will receive real treatment.
Placebo treatment will also be applied on eight different points of quadriceps muscle, but the equipment will be turned off.
|
|
|
Comparador activo: LLLT after muscle damage
Low Level Laser Therapy (LLLT) will be applied after the exercise protocol on one lower limb, while the other will receive placebo treatment.
Phototherapy will be applied with an equipment of 810nm and a cluster with five diodes on eight different points of quadriceps muscle, totalizing a dosage of 240J.
|
|
|
Comparador de placebos: Placebo LLLT after muscle damage
Placebo LLLT will be applied after the exercise protocol on one lower limb, while the other will receive real treatment.
Placebo treatment will also be applied on eight different points of quadriceps muscle, but the equipment will be turned off.
|
¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
|
Knee extensors isometric peak torque (Nm)
Periodo de tiempo: Baseline and 24, 48 and 72 hours follow-up
|
Isokinetic Dynamometer
|
Baseline and 24, 48 and 72 hours follow-up
|
Medidas de resultado secundarias
Medida de resultado |
Periodo de tiempo |
|---|---|
|
Knee extensors soreness (Visual Analogue scale)
Periodo de tiempo: Baseline and 24, 48 and 72 hours follow-up
|
Baseline and 24, 48 and 72 hours follow-up
|
|
Knee extensors echo intensity (number of white and black pixels)
Periodo de tiempo: Baseline and 24, 48 and 72 hours follow-up
|
Baseline and 24, 48 and 72 hours follow-up
|
Colaboradores e Investigadores
Patrocinador
Investigadores
- Director de estudio: Bruno Baroni, phD, Federal University of Health Science of Porto Alegre
Fechas de registro del estudio
Fechas importantes del estudio
Inicio del estudio
Finalización primaria (Actual)
Finalización del estudio (Actual)
Fechas de registro del estudio
Enviado por primera vez
Primero enviado que cumplió con los criterios de control de calidad
Publicado por primera vez (Estimar)
Actualizaciones de registros de estudio
Última actualización publicada (Estimar)
Última actualización enviada que cumplió con los criterios de control de calidad
Última verificación
Más información
Términos relacionados con este estudio
Palabras clave
Otros números de identificación del estudio
- 38076514.0.0000.5345
Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .