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Internet Supported Group Cognitive Behavior Therapy (CBT) for Hoarding Disorder (HD)

2017年8月15日 更新者：Christian Rück、Karolinska Institutet

Internet Supported Group Cognitive Behavior Therapy for Hoarding Disorder - A Pilot Study

The primary aim is to develop, and test the feasibility and efficacy of, a manual based, cognitive behaviour therapy (CBT) treatment for Hoarding Disorder (HD) delivered in a group format combined with an Internet support system. The investigators' secondary aim is to investigate the neurocognitive profile of the participants before and after treatment in order to explore if the treatment might have an impact on neurocognitive functioning and if certain neurocognitive profiles predict outcome.

For the primary aim, the investigators hypothesize that the treatment will be acceptable to participants and decrease symptoms of hoarding. Regarding the secondary aim, the investigators hypothesize that deficiencies in executive functioning, as measured with a neurocognitive battery, will reduce upon completion of treatment and that baseline executive function will be associated with treatment outcome.

研究概览

地位

完全的

条件

干预/治疗

研究类型

介入性

注册 (实际的)

20

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。

学习地点

  • 瑞典
      • Stockholm、瑞典
        • Psykiatri Nordväst, Stockholms Läns Sjukvårdsområde (SLSO), Stockholms Läns Landsting

参与标准

研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

18年 及以上 (成人、年长者)

接受健康志愿者

不

有资格学习的性别

全部

描述

  • Inclusion criteria:

    • Outpatients
    • Male or female
    • ≥ 18 years of age
    • Currently living in Stockholm county
    • Primary diagnosis of Hoarding Disorder according to DSM-5
    • Signed informed consent
    • Regular access to a computer with Internet and ability to use Internet
    • Access to a mobile phone
    • Able to participate in group sessions

  • Exclusion criteria:

    • Current substance dependence or misuse
    • Life time bipolar disorder or psychosis
    • Severe self-rated depressive symptoms (score ≥ 35 on MADRS-S)
    • Suicidal ideation (score > 4 on item 9 in MADRS-S)
    • Psychotropic medication changes within two months prior to the treatment
    • Other current psychological treatment that could affect hoarding symptoms
    • Has received more than 10 CBT sessions for Hoarding Disorder

学习计划

本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。

研究是如何设计的？

设计细节

  • 主要用途：治疗
  • 分配：不适用
  • 介入模型：单组作业
  • 屏蔽：无（打开标签）

武器和干预

参与者组/臂
干预/治疗
实验性的：CBT with Internet support
16 sessions of Cognitive behavior therapy in group with Internet support between group sessions
行为的：认知行为疗法
其他名称：
  • CBT
行为的：Internet support

研究衡量的是什么？

主要结果指标

结果测量
措施说明
大体时间
Saving Inventory - Revised (SI-R)
大体时间：Change from baseline to treatment week 8,16, 3- and 12-month follow-up
The SI-R is a 23-item self-report questionnaire. It assesses hoarding symptoms in 3 sub-scales: difficulty discarding, clutter and excessive acquisition.
Change from baseline to treatment week 8,16, 3- and 12-month follow-up

次要结果测量

结果测量
措施说明
大体时间
Hoarding Rating Scale - Self Report (HRS-SR)
大体时间：Weekly change during treatment, weeks 1-15
A 5-item self-report questionnaire assessing hoarding symptoms.
Weekly change during treatment, weeks 1-15
Saving Cognitions Inventory (SCI)
大体时间：Change from baseline to treatment week 8,16, 3- and 12-month follow-up
The questionnaire is a 24-item self-report questionnaire assessing beliefs and attitudes participants experience when trying to discard items. It is divided in 4 subscales:emotional attachment to objects, beliefs about objects as memory aids, responsibility for not wasting possessions, and the need for control over possessions.
Change from baseline to treatment week 8,16, 3- and 12-month follow-up
Clutter Image Rating (CIR)
大体时间：Change from baseline to treatment week 8,16, 3- and 12-month follow-up
This scale consists of three sets of photographs each containing nine photos of a single room with varying levels of clutter. Study participants will select the photograph that best resembles his or her own home. The study investigators will also conduct blinded ratings of the same photos.
Change from baseline to treatment week 8,16, 3- and 12-month follow-up
Global Assessment of Functioning (GAF)
大体时间：Change from baseline to treatment week 8,16, 3- and 12-month follow-up
A scale used to rate the social, occupational, and psychological functioning of the study participants.
Change from baseline to treatment week 8,16, 3- and 12-month follow-up
Clinical global impression (CGI)
大体时间：Change from baseline to treatment week 8,16, 3- and 12-month follow-up
A 7 point scale to rate how much the patient's illness has improved or worsened relative to a baseline state at the beginning of the intervention.
Change from baseline to treatment week 8,16, 3- and 12-month follow-up
EuroQol- 5 Dimension (EQ-5D)
大体时间：Change from baseline to treatment week 8,16, 3- and 12-month follow-up
A self-rating scale assessing quality of life i 5 dimensions.
Change from baseline to treatment week 8,16, 3- and 12-month follow-up
Trimbos and Institute of Medical Technology Assessment Cost Questionnaire for Psychiatry (TIC-P)
大体时间：Change from baseline to treatment week 8,16, 3- and 12-month follow-up
In this questionnaire, study participants register their monthly health care consumption (e.g. GP visits) as well as time spent in informal health enhancing activities (e.g. self-help groups and informal care from friends). Additionally, work loss and work cutback both at work and in the domestic realm is measured.
Change from baseline to treatment week 8,16, 3- and 12-month follow-up

其他结果措施

结果测量
措施说明
大体时间
Hoarding disorder diagnosis
大体时间：Change from baseline to treatment week 8,16, 3- and 12-month follow-up
Presence of Hoarding Disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Assessed by the investigators using the Structured Interview for Hoarding Disorder.
Change from baseline to treatment week 8,16, 3- and 12-month follow-up
Comorbid psychiatric diagnoses
大体时间：Change from baseline to treatment week 8,16, 3- and 12-month follow-up
Presence of psychiatric diagnoses other than Hoarding Disorder. Assessed by the investigators using the M.I.N.I. International Neuropsychiatric Interview (M.I.N.I. 6.0).
Change from baseline to treatment week 8,16, 3- and 12-month follow-up
Neuropsychological Test Battery (CANTAB)
大体时间：Change from baseline to treatment week 16
Cambridge Automated Neuropsychological Test Battery (CANTAB) will be used to test the study participants in 3 aspects of executive function: shifting and flexibility of attention, visuospatial working memory and response inhibition
Change from baseline to treatment week 16
Client Satisfaction Questionnaire - 8 (CSQ-8)
大体时间：At treatment week 16
An 8-item questionnaire measuring treatment satisfaction and acceptability.
At treatment week 16
Homework adherence
大体时间：Weekly change during treatment, weeks 1-15
Self-reported time spent on homework each week.
Weekly change during treatment, weeks 1-15

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

Karolinska Institutet

调查人员

  • 首席研究员：Christian Rück, Assoc Prof、Karolinska Institutet

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2015年10月1日

初级完成 (实际的)

2017年6月1日

研究完成 (实际的)

2017年6月1日

研究注册日期

首次提交

2015年10月13日

首先提交符合 QC 标准的

2015年10月21日

首次发布 (估计)

2015年10月23日

研究记录更新

最后更新发布 (实际的)

2017年8月18日

上次提交的符合 QC 标准的更新

2017年8月15日

最后验证

2017年8月1日

更多信息

与本研究相关的术语

其他相关的 MeSH 术语

其他研究编号

  • Hoarding Pilot

此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.

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