Internet Supported Group Cognitive Behavior Therapy (CBT) for Hoarding Disorder (HD)
15 augusti 2017 uppdaterad av: Christian Rück, Karolinska Institutet
Internet Supported Group Cognitive Behavior Therapy for Hoarding Disorder - A Pilot Study
The primary aim is to develop, and test the feasibility and efficacy of, a manual based, cognitive behaviour therapy (CBT) treatment for Hoarding Disorder (HD) delivered in a group format combined with an Internet support system. The investigators' secondary aim is to investigate the neurocognitive profile of the participants before and after treatment in order to explore if the treatment might have an impact on neurocognitive functioning and if certain neurocognitive profiles predict outcome.
For the primary aim, the investigators hypothesize that the treatment will be acceptable to participants and decrease symptoms of hoarding. Regarding the secondary aim, the investigators hypothesize that deficiencies in executive functioning, as measured with a neurocognitive battery, will reduce upon completion of treatment and that baseline executive function will be associated with treatment outcome.
Studieöversikt
Status
Avslutad
Betingelser
Intervention / Behandling
Studietyp
Interventionell
Inskrivning (Faktisk)
20
Fas
- Inte tillämpbar
Kontakter och platser
Det här avsnittet innehåller kontaktuppgifter för dem som genomför studien och information om var denna studie genomförs.
Studieorter
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Stockholm, Sverige
- Psykiatri Nordväst, Stockholms Läns Sjukvårdsområde (SLSO), Stockholms Läns Landsting
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-
Deltagandekriterier
Forskare letar efter personer som passar en viss beskrivning, så kallade behörighetskriterier. Några exempel på dessa kriterier är en persons allmänna hälsotillstånd eller tidigare behandlingar.
Urvalskriterier
Åldrar som är berättigade till studier
18 år och äldre (Vuxen, Äldre vuxen)
Tar emot friska volontärer
Nej
Kön som är behöriga för studier
Allt
Beskrivning
Inclusion criteria:
- Outpatients
- Male or female
- ≥ 18 years of age
- Currently living in Stockholm county
- Primary diagnosis of Hoarding Disorder according to DSM-5
- Signed informed consent
- Regular access to a computer with Internet and ability to use Internet
- Access to a mobile phone
- Able to participate in group sessions
Exclusion criteria:
- Current substance dependence or misuse
- Life time bipolar disorder or psychosis
- Severe self-rated depressive symptoms (score ≥ 35 on MADRS-S)
- Suicidal ideation (score > 4 on item 9 in MADRS-S)
- Psychotropic medication changes within two months prior to the treatment
- Other current psychological treatment that could affect hoarding symptoms
- Has received more than 10 CBT sessions for Hoarding Disorder
Studieplan
Det här avsnittet ger detaljer om studieplanen, inklusive hur studien är utformad och vad studien mäter.
Hur är studien utformad?
Designdetaljer
- Primärt syfte: Behandling
- Tilldelning: N/A
- Interventionsmodell: Enskild gruppuppgift
- Maskning: Ingen (Open Label)
Vapen och interventioner
Deltagargrupp / Arm |
Intervention / Behandling |
|---|---|
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Experimentell: CBT with Internet support
16 sessions of Cognitive behavior therapy in group with Internet support between group sessions
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Andra namn:
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Vad mäter studien?
Primära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
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Saving Inventory - Revised (SI-R)
Tidsram: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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The SI-R is a 23-item self-report questionnaire.
It assesses hoarding symptoms in 3 sub-scales: difficulty discarding, clutter and excessive acquisition.
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Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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Sekundära resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
|
Hoarding Rating Scale - Self Report (HRS-SR)
Tidsram: Weekly change during treatment, weeks 1-15
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A 5-item self-report questionnaire assessing hoarding symptoms.
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Weekly change during treatment, weeks 1-15
|
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Saving Cognitions Inventory (SCI)
Tidsram: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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The questionnaire is a 24-item self-report questionnaire assessing beliefs and attitudes participants experience when trying to discard items.
It is divided in 4 subscales:emotional attachment to objects, beliefs about objects as memory aids, responsibility for not wasting possessions, and the need for control over possessions.
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Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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Clutter Image Rating (CIR)
Tidsram: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
|
This scale consists of three sets of photographs each containing nine photos of a single room with varying levels of clutter.
Study participants will select the photograph that best resembles his or her own home.
The study investigators will also conduct blinded ratings of the same photos.
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Change from baseline to treatment week 8,16, 3- and 12-month follow-up
|
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Global Assessment of Functioning (GAF)
Tidsram: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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A scale used to rate the social, occupational, and psychological functioning of the study participants.
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Change from baseline to treatment week 8,16, 3- and 12-month follow-up
|
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Clinical global impression (CGI)
Tidsram: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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A 7 point scale to rate how much the patient's illness has improved or worsened relative to a baseline state at the beginning of the intervention.
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Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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EuroQol- 5 Dimension (EQ-5D)
Tidsram: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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A self-rating scale assessing quality of life i 5 dimensions.
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Change from baseline to treatment week 8,16, 3- and 12-month follow-up
|
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Trimbos and Institute of Medical Technology Assessment Cost Questionnaire for Psychiatry (TIC-P)
Tidsram: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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In this questionnaire, study participants register their monthly health care consumption (e.g.
GP visits) as well as time spent in informal health enhancing activities (e.g.
self-help groups and informal care from friends).
Additionally, work loss and work cutback both at work and in the domestic realm is measured.
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Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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Andra resultatmått
Resultatmått |
Åtgärdsbeskrivning |
Tidsram |
|---|---|---|
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Hoarding disorder diagnosis
Tidsram: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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Presence of Hoarding Disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5).
Assessed by the investigators using the Structured Interview for Hoarding Disorder.
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Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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Comorbid psychiatric diagnoses
Tidsram: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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Presence of psychiatric diagnoses other than Hoarding Disorder.
Assessed by the investigators using the M.I.N.I.
International Neuropsychiatric Interview (M.I.N.I. 6.0).
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Change from baseline to treatment week 8,16, 3- and 12-month follow-up
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Neuropsychological Test Battery (CANTAB)
Tidsram: Change from baseline to treatment week 16
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Cambridge Automated Neuropsychological Test Battery (CANTAB) will be used to test the study participants in 3 aspects of executive function: shifting and flexibility of attention, visuospatial working memory and response inhibition
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Change from baseline to treatment week 16
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Client Satisfaction Questionnaire - 8 (CSQ-8)
Tidsram: At treatment week 16
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An 8-item questionnaire measuring treatment satisfaction and acceptability.
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At treatment week 16
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Homework adherence
Tidsram: Weekly change during treatment, weeks 1-15
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Self-reported time spent on homework each week.
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Weekly change during treatment, weeks 1-15
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Samarbetspartners och utredare
Det är här du hittar personer och organisationer som är involverade i denna studie.
Sponsor
Utredare
- Huvudutredare: Christian Rück, Assoc Prof, Karolinska Institutet
Studieavstämningsdatum
Dessa datum spårar framstegen för inlämningar av studieposter och sammanfattande resultat till ClinicalTrials.gov. Studieposter och rapporterade resultat granskas av National Library of Medicine (NLM) för att säkerställa att de uppfyller specifika kvalitetskontrollstandarder innan de publiceras på den offentliga webbplatsen.
Studera stora datum
Studiestart (Faktisk)
1 oktober 2015
Primärt slutförande (Faktisk)
1 juni 2017
Avslutad studie (Faktisk)
1 juni 2017
Studieregistreringsdatum
Först inskickad
13 oktober 2015
Först inskickad som uppfyllde QC-kriterierna
21 oktober 2015
Första postat (Uppskatta)
23 oktober 2015
Uppdateringar av studier
Senaste uppdatering publicerad (Faktisk)
18 augusti 2017
Senaste inskickade uppdateringen som uppfyllde QC-kriterierna
15 augusti 2017
Senast verifierad
1 augusti 2017
Mer information
Termer relaterade till denna studie
Ytterligare relevanta MeSH-villkor
Andra studie-ID-nummer
- Hoarding Pilot
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