Cortical Activation in Individuals With Finger Amputation During Mirror Versus Imagery Treatment
Goals : ( a) to examine differences in cortical activity during hand movements with a mirror compared to imagery of the same movements, and (b) to examine correlation between cortical activity during imagery or mirror treatment and the pain and performance measures in finger amputees.
A cross-sectional study of 20 subjects in a Functional Magnetic Resonance Imaging (fMRI) preforming mirror therapy hand movement and imagery hand movement. Also, Visual Analogue Scale for pain and the Disability of the Arm, Shoulder and Hand (DASH) questionnaire and Jebsen Taylor Hand Function Test will be used.
研究概览
详细说明
Goals : ( a) to examine differences in cortical activity during hand movements with a mirror compared to imagery of the same movements, and (b) to examine correlation between cortical activity during imagery or mirror treatment and the pain and performance measures in finger amputees.
A cross-sectional one-meeting study of 20 subjects (finger amputees) in a Functional Magnetic Resonance Imaging (fMRI) preforming mirror therapy hand movement and imagery hand movement. Also, Visual Analogue Scale for pain and the Disability of the Arm, Shoulder and Hand (DASH) questionnaire and Jebsen Taylor Hand Function Test will be used.
研究类型
注册 (预期的)
阶段
- 不适用
联系人和位置
学习地点
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Jerusalem、以色列、91240
- Hadassah Medical Center
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Following unilateral traumatic finger or fingers amputation (1 to 3 fingers)
- Self-reported limited functionality, sensory disorder or pain
Exclusion Criteria:
- Are not comparable with MRI restrictions
- Chronic pain disease
- Psychiatric condition
学习计划
研究是如何设计的？
设计细节
- 主要用途：基础科学
- 分配：不适用
- 介入模型：单组作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Amputees
The subjects will receive both mirror and imagery treatments in a cross-over design.
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The healthy hand will be mirrored and the amputated hand unseen by the subject while performing hand movements.
The subject will be asked to imagine performing hand movements.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Cortical activity
大体时间：1 hour
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Activation of supplementary motor area (SMA), S1 and M1.
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1 hour
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Visual analogue scale
大体时间：10 minutes
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Filled by the subject for subjective pain in residuum discomfort.
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10 minutes
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Disability of the Arm, Shoulder and Hand
大体时间：30 minutes
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Questionnaire regarding the disability and daily activities difficulties.
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30 minutes
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The Jebsen Taylor Hand Function Test
大体时间：30 minutes
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Standard evaluation of hands functionality.
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30 minutes
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合作者和调查者
出版物和有用的链接
一般刊物
- Chan BL, Witt R, Charrow AP, Magee A, Howard R, Pasquina PF, Heilman KM, Tsao JW. Mirror therapy for phantom limb pain. N Engl J Med. 2007 Nov 22;357(21):2206-7. doi: 10.1056/NEJMc071927. No abstract available.
- Deconinck FJ, Smorenburg AR, Benham A, Ledebt A, Feltham MG, Savelsbergh GJ. Reflections on mirror therapy: a systematic review of the effect of mirror visual feedback on the brain. Neurorehabil Neural Repair. 2015 May;29(4):349-61. doi: 10.1177/1545968314546134. Epub 2014 Aug 26.
研究记录日期
研究主要日期
学习开始
初级完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他研究编号
- Mirror- HMO-CTIL
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