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Estrogen and Cooperation, Competitiveness, and Risk Preferences (FELICIA)

2020年10月28日 更新者:Frederik Graff、RWTH Aachen University

The Effect of Estrogen Levels on Cooperative and Competitive Decision Making and Risk Preferences

This study observes the effects of female cycle hormones on cooperation, competitiveness and risk preferences under experimental conditions. Especially, the causal effect of estradiol is isolated.

研究概览

地位

未知

详细说明

Behavioural theories assume that, as a result of natural selection, women undergo a brief, unconscious change in some psychological aspects during ovulation. This short-term change, "ovulatory shift", is assumed to aim to increase the probability of successful reproduction in the decisive days of the female cycle. Amongst others, it is assumed that women behave particularly uncooperatively and particularly competitively towards other women during the fertile days. Though, empirical evidence is ambiguous.

The effect on risk preferences is unclear. Theory generally assumes that female risk aversion increases in the fertile days. However, empirical studies find partly positive and partly negative correlations.

Within the scope of this study, estradiol levels which are collected in the clinical treatment of patients in the Clinic for Gynaecological Endocrinology and Reproductive Medicine are to be linked with the behavioural economic measures of cooperation, competitiveness, and risk preferences, which are collected using questionnaires or a computer-based decision task.

The aim of the research project is to quasi-experimentally isolate the effect of estradiol on competitiveness, cooperation and risk preferences of women.

No study known to us has ever been able to realize a comparable quasi-experimental design which is necessary to isolate the causal effect of estradiol on different behavioural measures.

In the experimental group, a sample of approx. 50 women in fertility treatment (In Vitro Fertilization/Intracytoplasmic Sperm Injection (IVF/ICSI), long Gonadotropin releasing Hormone (GnRH) agonist protocol) is surveyed. This allows us to create a quasi-experimental design in which the estradiol level is exogenously manipulated and regularly measured.

A random sample of 30 male students of Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University serves as a control group.

We realize a longitudinal section design with measurement repetitions, which allows inter- and intrapersonal comparisons. A three-stage procedure with two measuring points and a preliminary clarification meeting is planned.

The following measuring instruments are used to record competitiveness, cooperation and risk preference: SOEP Risk Attitude, Social Value Orientation German A, The cooperative and competitive Personality Scale German, Risk aversion, Willingness to compete.

研究类型

观察性的

注册 (预期的)

80

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

      • Aachen、德国、52074
        • 招聘中
        • RWTH Aachen University Hospital
        • 接触:
        • 接触:
        • 首席研究员:
          • Benjamin Rösing

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

18年 及以上 (成人、年长者)

接受健康志愿者

不

有资格学习的性别

全部

取样方法

非概率样本

研究人群

Women in fertility treatment

描述

Inclusion Criteria:

Patients

  1. female
  2. patient in fertility treatment according to Long GnRH Agonist Protocol
  3. 18 years and older
  4. written declaration of consent
  5. persons who are contractually capable and mentally able and willing to follow the instructions of the study staff
  6. understanding of the German language (written and spoken)

Control group

  1. male
  2. 18 Years and older
  3. written declaration of consent
  4. persons who are contractually capable and mentally able and willing to follow the instructions of the study staff
  5. understanding of the German language (written and spoken)

Exclusion Criteria:

Patients

  1. Illiterate
  2. pregnant and breastfeeding women
  3. persons who are accommodated in an institution on official or court order
  4. persons in a dependent or employment relationship with the auditor
  5. simultaneous participation in another clinical trial

Control group

  1. Illiterate
  2. persons who are accommodated in an institution on official or court order
  3. persons in a dependent or employment relationship with the auditor
  4. simultaneous participation in another clinical trial

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 观测模型:其他
  • 时间观点:预期

队列和干预

团体/队列
female patients
women in fertility treatment according to Long GnRH Agonist Protocol
control group
random sample of male students

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Change of E2 [mg/l]
大体时间:Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of estradiol (E2) in mg/l
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of LH [mg/l]
大体时间:Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of the luteinizing hormone (LH) in mg/l
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Prog [mg/l]
大体时间:Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of progesterone (Prog) in mg/l
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Cooperation 1
大体时间:Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to cooperate measured via the Social Value Orientation German A (Murphy et al. 2011)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Competitiveness 1
大体时间:Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to compete measured via the cooperative and competitive Personality Scale German (Lu et al. 2006)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk Preference 1
大体时间:Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk preferences measured via the SOEP Risk Attitude (DIW Berlin)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Cooperation 2
大体时间:Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to cooperate measured via the cooperative and competitive Personality Scale German (Lu et al. 2006)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Competitiveness 2
大体时间:Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to compete measured via the Willingness to compete measure based on Niederle & Vesterlund (2007)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk Preference 2
大体时间:Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk preferences measured via the Risk aversion measure by Holt & Laury (2002)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Benjamin Rösing, Dr.、RWTH Aachen

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

一般刊物

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2018年10月8日

初级完成 (预期的)

2021年12月30日

研究完成 (预期的)

2021年12月30日

研究注册日期

首次提交

2018年6月21日

首先提交符合 QC 标准的

2018年6月30日

首次发布 (实际的)

2018年7月12日

研究记录更新

最后更新发布 (实际的)

2020年10月29日

上次提交的符合 QC 标准的更新

2020年10月28日

最后验证

2020年10月1日

更多信息

与本研究相关的术语

其他研究编号

  • 18-053

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)?

不

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

在美国制造并从美国出口的产品

不

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