Denne siden ble automatisk oversatt og nøyaktigheten av oversettelsen er ikke garantert. Vennligst referer til engelsk versjon for en kildetekst.

Estrogen and Cooperation, Competitiveness, and Risk Preferences (FELICIA)

28. oktober 2020 oppdatert av: Frederik Graff, RWTH Aachen University

The Effect of Estrogen Levels on Cooperative and Competitive Decision Making and Risk Preferences

This study observes the effects of female cycle hormones on cooperation, competitiveness and risk preferences under experimental conditions. Especially, the causal effect of estradiol is isolated.

Studieoversikt

Status

Ukjent

Detaljert beskrivelse

Behavioural theories assume that, as a result of natural selection, women undergo a brief, unconscious change in some psychological aspects during ovulation. This short-term change, "ovulatory shift", is assumed to aim to increase the probability of successful reproduction in the decisive days of the female cycle. Amongst others, it is assumed that women behave particularly uncooperatively and particularly competitively towards other women during the fertile days. Though, empirical evidence is ambiguous.

The effect on risk preferences is unclear. Theory generally assumes that female risk aversion increases in the fertile days. However, empirical studies find partly positive and partly negative correlations.

Within the scope of this study, estradiol levels which are collected in the clinical treatment of patients in the Clinic for Gynaecological Endocrinology and Reproductive Medicine are to be linked with the behavioural economic measures of cooperation, competitiveness, and risk preferences, which are collected using questionnaires or a computer-based decision task.

The aim of the research project is to quasi-experimentally isolate the effect of estradiol on competitiveness, cooperation and risk preferences of women.

No study known to us has ever been able to realize a comparable quasi-experimental design which is necessary to isolate the causal effect of estradiol on different behavioural measures.

In the experimental group, a sample of approx. 50 women in fertility treatment (In Vitro Fertilization/Intracytoplasmic Sperm Injection (IVF/ICSI), long Gonadotropin releasing Hormone (GnRH) agonist protocol) is surveyed. This allows us to create a quasi-experimental design in which the estradiol level is exogenously manipulated and regularly measured.

A random sample of 30 male students of Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University serves as a control group.

We realize a longitudinal section design with measurement repetitions, which allows inter- and intrapersonal comparisons. A three-stage procedure with two measuring points and a preliminary clarification meeting is planned.

The following measuring instruments are used to record competitiveness, cooperation and risk preference: SOEP Risk Attitude, Social Value Orientation German A, The cooperative and competitive Personality Scale German, Risk aversion, Willingness to compete.

Studietype

Observasjonsmessig

Registrering (Forventet)

80

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

      • Aachen, Tyskland, 52074
        • Rekruttering
        • RWTH Aachen University Hospital
        • Ta kontakt med:
        • Ta kontakt med:
        • Hovedetterforsker:
          • Benjamin Rösing

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

18 år og eldre (Voksen, Eldre voksen)

Tar imot friske frivillige

Nei

Kjønn som er kvalifisert for studier

Alle

Prøvetakingsmetode

Ikke-sannsynlighetsprøve

Studiepopulasjon

Women in fertility treatment

Beskrivelse

Inclusion Criteria:

Patients

  1. female
  2. patient in fertility treatment according to Long GnRH Agonist Protocol
  3. 18 years and older
  4. written declaration of consent
  5. persons who are contractually capable and mentally able and willing to follow the instructions of the study staff
  6. understanding of the German language (written and spoken)

Control group

  1. male
  2. 18 Years and older
  3. written declaration of consent
  4. persons who are contractually capable and mentally able and willing to follow the instructions of the study staff
  5. understanding of the German language (written and spoken)

Exclusion Criteria:

Patients

  1. Illiterate
  2. pregnant and breastfeeding women
  3. persons who are accommodated in an institution on official or court order
  4. persons in a dependent or employment relationship with the auditor
  5. simultaneous participation in another clinical trial

Control group

  1. Illiterate
  2. persons who are accommodated in an institution on official or court order
  3. persons in a dependent or employment relationship with the auditor
  4. simultaneous participation in another clinical trial

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

  • Observasjonsmodeller: Annen
  • Tidsperspektiver: Potensielle

Kohorter og intervensjoner

Gruppe / Kohort
female patients
women in fertility treatment according to Long GnRH Agonist Protocol
control group
random sample of male students

Hva måler studien?

Primære resultatmål

Resultatmål
Tiltaksbeskrivelse
Tidsramme
Change of E2 [mg/l]
Tidsramme: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of estradiol (E2) in mg/l
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of LH [mg/l]
Tidsramme: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of the luteinizing hormone (LH) in mg/l
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Prog [mg/l]
Tidsramme: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of progesterone (Prog) in mg/l
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Cooperation 1
Tidsramme: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to cooperate measured via the Social Value Orientation German A (Murphy et al. 2011)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Competitiveness 1
Tidsramme: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to compete measured via the cooperative and competitive Personality Scale German (Lu et al. 2006)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk Preference 1
Tidsramme: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk preferences measured via the SOEP Risk Attitude (DIW Berlin)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Cooperation 2
Tidsramme: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to cooperate measured via the cooperative and competitive Personality Scale German (Lu et al. 2006)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Competitiveness 2
Tidsramme: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to compete measured via the Willingness to compete measure based on Niederle & Vesterlund (2007)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk Preference 2
Tidsramme: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk preferences measured via the Risk aversion measure by Holt & Laury (2002)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Etterforskere

  • Hovedetterforsker: Benjamin Rösing, Dr., RWTH Aachen

Publikasjoner og nyttige lenker

Den som er ansvarlig for å legge inn informasjon om studien leverer frivillig disse publikasjonene. Disse kan handle om alt relatert til studiet.

Generelle publikasjoner

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart (Faktiske)

8. oktober 2018

Primær fullføring (Forventet)

30. desember 2021

Studiet fullført (Forventet)

30. desember 2021

Datoer for studieregistrering

Først innsendt

21. juni 2018

Først innsendt som oppfylte QC-kriteriene

30. juni 2018

Først lagt ut (Faktiske)

12. juli 2018

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

29. oktober 2020

Siste oppdatering sendt inn som oppfylte QC-kriteriene

28. oktober 2020

Sist bekreftet

1. oktober 2020

Mer informasjon

Begreper knyttet til denne studien

Andre studie-ID-numre

  • 18-053

Plan for individuelle deltakerdata (IPD)

Planlegger du å dele individuelle deltakerdata (IPD)?

Nei

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

Nei

Studerer et amerikansk FDA-regulert enhetsprodukt

Nei

produkt produsert i og eksportert fra USA

Nei

Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .

Abonnere