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Estrogen and Cooperation, Competitiveness, and Risk Preferences (FELICIA)

28 de octubre de 2020 actualizado por: Frederik Graff, RWTH Aachen University

The Effect of Estrogen Levels on Cooperative and Competitive Decision Making and Risk Preferences

This study observes the effects of female cycle hormones on cooperation, competitiveness and risk preferences under experimental conditions. Especially, the causal effect of estradiol is isolated.

Descripción general del estudio

Estado

Desconocido

Descripción detallada

Behavioural theories assume that, as a result of natural selection, women undergo a brief, unconscious change in some psychological aspects during ovulation. This short-term change, "ovulatory shift", is assumed to aim to increase the probability of successful reproduction in the decisive days of the female cycle. Amongst others, it is assumed that women behave particularly uncooperatively and particularly competitively towards other women during the fertile days. Though, empirical evidence is ambiguous.

The effect on risk preferences is unclear. Theory generally assumes that female risk aversion increases in the fertile days. However, empirical studies find partly positive and partly negative correlations.

Within the scope of this study, estradiol levels which are collected in the clinical treatment of patients in the Clinic for Gynaecological Endocrinology and Reproductive Medicine are to be linked with the behavioural economic measures of cooperation, competitiveness, and risk preferences, which are collected using questionnaires or a computer-based decision task.

The aim of the research project is to quasi-experimentally isolate the effect of estradiol on competitiveness, cooperation and risk preferences of women.

No study known to us has ever been able to realize a comparable quasi-experimental design which is necessary to isolate the causal effect of estradiol on different behavioural measures.

In the experimental group, a sample of approx. 50 women in fertility treatment (In Vitro Fertilization/Intracytoplasmic Sperm Injection (IVF/ICSI), long Gonadotropin releasing Hormone (GnRH) agonist protocol) is surveyed. This allows us to create a quasi-experimental design in which the estradiol level is exogenously manipulated and regularly measured.

A random sample of 30 male students of Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University serves as a control group.

We realize a longitudinal section design with measurement repetitions, which allows inter- and intrapersonal comparisons. A three-stage procedure with two measuring points and a preliminary clarification meeting is planned.

The following measuring instruments are used to record competitiveness, cooperation and risk preference: SOEP Risk Attitude, Social Value Orientation German A, The cooperative and competitive Personality Scale German, Risk aversion, Willingness to compete.

Tipo de estudio

De observación

Inscripción (Anticipado)

80

Contactos y Ubicaciones

Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.

Ubicaciones de estudio

      • Aachen, Alemania, 52074
        • Reclutamiento
        • RWTH Aachen University Hospital
        • Contacto:
        • Contacto:
          • Benjamin Rösing, Dr.
          • Número de teléfono: +492418027066 +492418027066
          • Correo electrónico: broesing@ukaachen.de
        • Investigador principal:
          • Benjamin Rösing

Criterios de participación

Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.

Criterio de elegibilidad

Edades elegibles para estudiar

18 años y mayores (Adulto, Adulto Mayor)

Acepta Voluntarios Saludables

No

Géneros elegibles para el estudio

Todos

Método de muestreo

Muestra no probabilística

Población de estudio

Women in fertility treatment

Descripción

Inclusion Criteria:

Patients

  1. female
  2. patient in fertility treatment according to Long GnRH Agonist Protocol
  3. 18 years and older
  4. written declaration of consent
  5. persons who are contractually capable and mentally able and willing to follow the instructions of the study staff
  6. understanding of the German language (written and spoken)

Control group

  1. male
  2. 18 Years and older
  3. written declaration of consent
  4. persons who are contractually capable and mentally able and willing to follow the instructions of the study staff
  5. understanding of the German language (written and spoken)

Exclusion Criteria:

Patients

  1. Illiterate
  2. pregnant and breastfeeding women
  3. persons who are accommodated in an institution on official or court order
  4. persons in a dependent or employment relationship with the auditor
  5. simultaneous participation in another clinical trial

Control group

  1. Illiterate
  2. persons who are accommodated in an institution on official or court order
  3. persons in a dependent or employment relationship with the auditor
  4. simultaneous participation in another clinical trial

Plan de estudios

Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.

¿Cómo está diseñado el estudio?

Detalles de diseño

  • Modelos observacionales: Otro
  • Perspectivas temporales: Futuro

Cohortes e Intervenciones

Grupo / Cohorte
female patients
women in fertility treatment according to Long GnRH Agonist Protocol
control group
random sample of male students

¿Qué mide el estudio?

Medidas de resultado primarias

Medida de resultado
Medida Descripción
Periodo de tiempo
Change of E2 [mg/l]
Periodo de tiempo: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of estradiol (E2) in mg/l
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of LH [mg/l]
Periodo de tiempo: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of the luteinizing hormone (LH) in mg/l
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Prog [mg/l]
Periodo de tiempo: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of blood concentration of progesterone (Prog) in mg/l
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Cooperation 1
Periodo de tiempo: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to cooperate measured via the Social Value Orientation German A (Murphy et al. 2011)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Competitiveness 1
Periodo de tiempo: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to compete measured via the cooperative and competitive Personality Scale German (Lu et al. 2006)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk Preference 1
Periodo de tiempo: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk preferences measured via the SOEP Risk Attitude (DIW Berlin)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Cooperation 2
Periodo de tiempo: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to cooperate measured via the cooperative and competitive Personality Scale German (Lu et al. 2006)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Competitiveness 2
Periodo de tiempo: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of willingness to compete measured via the Willingness to compete measure based on Niederle & Vesterlund (2007)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk Preference 2
Periodo de tiempo: Approx. 10 days after application of GnRH agonist and again approx. 14 days later
Change of Risk preferences measured via the Risk aversion measure by Holt & Laury (2002)
Approx. 10 days after application of GnRH agonist and again approx. 14 days later

Colaboradores e Investigadores

Aquí es donde encontrará personas y organizaciones involucradas en este estudio.

Patrocinador

Investigadores

  • Investigador principal: Benjamin Rösing, Dr., RWTH Aachen

Publicaciones y enlaces útiles

La persona responsable de ingresar información sobre el estudio proporciona voluntariamente estas publicaciones. Estos pueden ser sobre cualquier cosa relacionada con el estudio.

Publicaciones Generales

Fechas de registro del estudio

Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados ​​por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.

Fechas importantes del estudio

Inicio del estudio (Actual)

8 de octubre de 2018

Finalización primaria (Anticipado)

30 de diciembre de 2021

Finalización del estudio (Anticipado)

30 de diciembre de 2021

Fechas de registro del estudio

Enviado por primera vez

21 de junio de 2018

Primero enviado que cumplió con los criterios de control de calidad

30 de junio de 2018

Publicado por primera vez (Actual)

12 de julio de 2018

Actualizaciones de registros de estudio

Última actualización publicada (Actual)

29 de octubre de 2020

Última actualización enviada que cumplió con los criterios de control de calidad

28 de octubre de 2020

Última verificación

1 de octubre de 2020

Más información

Términos relacionados con este estudio

Otros números de identificación del estudio

  • 18-053

Plan de datos de participantes individuales (IPD)

¿Planea compartir datos de participantes individuales (IPD)?

No

Información sobre medicamentos y dispositivos, documentos del estudio

Estudia un producto farmacéutico regulado por la FDA de EE. UU.

No

Estudia un producto de dispositivo regulado por la FDA de EE. UU.

No

producto fabricado y exportado desde los EE. UU.

No

Esta información se obtuvo directamente del sitio web clinicaltrials.gov sin cambios. Si tiene alguna solicitud para cambiar, eliminar o actualizar los detalles de su estudio, comuníquese con register@clinicaltrials.gov. Tan pronto como se implemente un cambio en clinicaltrials.gov, también se actualizará automáticamente en nuestro sitio web. .

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