Effect of Remote Cognitive Intervention in Patients With Parkinson's Disease During the COVID-19 Pandemic (TELEPARK)
2022年7月26日 更新者：Istituto Nazionale di Ricovero e Cura per Anziani
Retrospective study to evaluate the effect of a remote cognitive-rehabilitative intervention during the Covid outbreak in subjects with Parkinson's disease.
研究概览
详细说明
Mild cognitive impairment is frequent among people with Parkinson's disease.
Cognitive training seems effective on cognitive status and for mitigating anxiety and depression.
With COVID-19 outbreak, such therapeutic interventions were delivered online.
This retrospective study was aimed at evaluating the effectiveness of an online cognitive treatment, carried out in COVID times and based on the Parkinson's-Adapted Cognitive Stimulation Therapy, on cognitive domains and mood in 18 older people with Parkinson's disease.
研究类型
观察性的
注册 (实际的)
18
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
-
-
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Ancona、意大利、60127
- IRCCS INRCA Hospital
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 孩子
- 成人
- 年长者
接受健康志愿者
不
有资格学习的性别
全部
取样方法
非概率样本
研究人群
Patients with Parkinson's disease that, after eight months of COVID-19 lockdown when all interventions were suspended, received an intensive digital cognitive rehabilitation treatment.
描述
Inclusion Criteria:
- Parkinson disease: Hoehn & Yahr's scale: 1-3 based on the UK PD Society Brain Bank
- mild cognitive impairment
- no cognitive training between March and October 2020
- presence of a family caregiver to access and use the online platform
Exclusion Criteria:
- other neurological diseases
- deep brain stimulation
- schizophrenia
- depression
- sensory deprivations that could interfere with the treatment
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
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Cognitive digital treatment
Cognitive digital treatment in patients with Parkinson's disease
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The remote cognitive-rehabilitation treatment was based on Parkinson's adapted cognitive stimulation therapy (CST).
Fourteen twice-weekly sessions were planned, followed by one session per week for a duration of six months for maintenance therapy.
The treatment took place in groups of 4 patients in remote mode through the Microsoft-Teams platform.
All subjects maintained the prescribed drug therapy and regular physiotherapy activity during the intervention.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
changes in cognitive status
大体时间：This evaluation was performed in the pre-COVID-19 period, at the beginning of the remote treatment (8 months from the pre-COVID evaluation), and at the end of the remote treatment (7 weeks from the start of the treatment)
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The Mini Mental State Examination (MMSE) was used to evaluate the cognitive status.The test consists of 2 parts: language (time orientation, registration and attention) and performance (recall, response to written/verbal commands, sriting ability and reproduction of complex polygons); the total score can range from 0 to 30, with a higher score indicating better function.
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This evaluation was performed in the pre-COVID-19 period, at the beginning of the remote treatment (8 months from the pre-COVID evaluation), and at the end of the remote treatment (7 weeks from the start of the treatment)
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
changes in cognitive domains
大体时间：This evaluation was performed in the pre-COVID-19 period, at the beginning of the remote treatment (8 months from the pre-COVID evaluation), and at the end of the remote treatment (7 weeks from the start of the treatment)
|
The Addembrooke's Cognitive Examination Battery (ACE-R) was used to evaluate the cognitive domains.
The ACE-R consists of six components evaluating separate cognitive domains.
A maximum score of 100 is weighted as follows: orientation (10), attention (8), memory(35), verbal fluency (14), language (28), and visuospatialability (5).
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This evaluation was performed in the pre-COVID-19 period, at the beginning of the remote treatment (8 months from the pre-COVID evaluation), and at the end of the remote treatment (7 weeks from the start of the treatment)
|
|
changes in thymic state
大体时间：This evaluation was performed in the pre-COVID-19 period, at the beginning of the remote treatment (8 months from the pre-COVID evaluation), and at the end of the remote treatment (7 weeks from the start of the treatment)
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The Geriatric Depression Scale-15 items (GDS-15 items) was used to evaluate the tymic state.This instrument evaluated depressive symptoms using yes/no answers.
Scores range between 0 and 15 points.
Higher scores indicate more severe depressive symptoms.
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This evaluation was performed in the pre-COVID-19 period, at the beginning of the remote treatment (8 months from the pre-COVID evaluation), and at the end of the remote treatment (7 weeks from the start of the treatment)
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2020年1月1日
初级完成 (实际的)
2020年10月31日
研究完成 (实际的)
2020年10月31日
研究注册日期
首次提交
2022年7月22日
首先提交符合 QC 标准的
2022年7月26日
首次发布 (实际的)
2022年7月27日
研究记录更新
最后更新发布 (实际的)
2022年7月27日
上次提交的符合 QC 标准的更新
2022年7月26日
最后验证
2022年7月1日
更多信息
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