Roods vs PNF for Upper Limb Function in Acute MCA Stroke (RVP-MCA)
2026年5月23日 更新者：Dr. Marium Zafar、University of Faisalabad
Comparison Between Roods Facilitatory Techniques and Sequential PNF Pattern on Upper Limb Function in Acute Phase of Middle Cerebral Artery Stroke Patients
Middle cerebral artery (MCA) stroke often causes weakness or stiffness in the arm and hand, making daily activities difficult.
This study compares two physical therapy approaches - Rood's facilitatory techniques (using touch, quick stretch, and ice to activate muscles) and PNF sequential patterns (using diagonal movement patterns) - to improve arm function in acute stroke patients.
Both groups will also receive neuromuscular electrical stimulation (NMES).
A total of 28 patients will be randomly assigned to one of two groups and receive treatment three times per week for eight weeks.
Arm function will be measured using the Fugl-Meyer Assessment, and muscle stiffness will be measured using the Modified Ashworth Scale before and after treatment.
研究概览
地位
邀请报名
详细说明
This is a single-blind, parallel-group randomized controlled trial.
The study will be conducted at three settings in Faisalabad, Pakistan: Allied Hospital, Madinah Teaching Hospital, and Shahid Heera's Health Clinic.
Adult patients (≥18 years) with CT or MRI-confirmed MCA stroke (ischemic or hemorrhagic), mild to moderate upper limb motor dysfunction (MRC ≥2), and cognitive competence (MoCA ≥19) will be included.
Exclusion criteria include severe comorbidities, fixed contractures, severe cognitive impairment, skin contraindications to sensory stimulation, and inability to provide consent.
A sample size of 28 participants (14 per group) was calculated using Rao soft app based on previous literature.
Participants will be randomly assigned using a computer-generated sequence.
The single-blind design keeps participants unaware of group allocation.
Group A receives NMES followed by Rood's facilitatory techniques: quick stretch before or during movement to activate muscle spindles, tactile stimulation (light stroking) over the muscle belly for 10-20 seconds, and icing for 5-7 seconds on the tendon or muscle surface immediately preceding activation.
Group B receives NMES followed by PNF sequential training using conventional upper limb diagonal functional patterns (D1 and D2).
PNF techniques include rhythmic initiation, dynamic reversals, repetitive contractions, and combination of isotonic contractions with moderate resistance, performing 8-12 repetitions per pattern over 20-30 minutes per session.
NMES parameters: biphasic waveform at 30-40Hz frequency with pulse duration of 200-300μs, producing comfortable visible contraction, administered for 30 minutes per session.
Both groups receive interventions three times per week for eight weeks.
Outcome measures: Fugl-Meyer Assessment for Upper Extremity (FMA-UE, score range 0-66) measures motor function; Modified Ashworth Scale (MAS, score range 0-4) measures muscle tone.
Assessments are conducted at baseline and post-intervention by a qualified physiotherapist.
Data will be analyzed using SPSS version 22.
研究类型
介入性
注册 (估计的)
28
阶段
- 不适用
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
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Punjab Province
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Faisalābad、Punjab Province、巴基斯坦、3800
- The University of Faisalabad
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 成人
接受健康志愿者
不
描述
Inclusion Criteria:
- Adults (40-60 years) with confirmed MCA stroke (ischemic or hemorrhagic) on neuroimaging (CT or MRI)
- Mild to moderate upper limb motor dysfunction with MRC ≥2 for proximal limb motor strength
- Cognitive competence to understand instructions (MoCA ≥19 or equivalent)
- First stroke, acute or subacute phase
- Willingness to provide written informed consent
- Both male and female genders
Exclusion Criteria:
- Severe coexisting medical disorders (heart, liver, kidney failure; malignant tumors)
- Fixed musculoskeletal abnormalities or contracture in affected upper limb
- Severe cognitive impairment or aphasia preventing adherence or consent (MMSE below threshold)
- Skin sores, ulcers, or hypersensitivity (e.g., to cold) contraindicated for sensory stimulation
- Refusal or inability to give informed consent
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Rood's Facilitatory Techniques Group
Participants receive neuromuscular electrical stimulation (NMES) followed by Rood's facilitatory techniques including quick stretch, tactile stimulation for 10-20 seconds over muscle belly, and icing for 5-7 seconds on tendon or muscle surface.
Interventions delivered three times per week for eight weeks.
|
Biphasic waveform NMES at 30-40Hz frequency with pulse duration of 200-300μs, producing comfortable but visible muscle contraction.
Applied to affected upper limb for 30 minutes per session, three times per week for eight weeks.
Quick stretch applied before or during movement to activate muscle spindles; tactile stimulation (light stroking) over muscle belly for 10-20 seconds; icing for 5-7 seconds on tendon or muscle surface immediately preceding activation.
Applied three times per week for eight weeks following NMES.
|
|
有源比较器：PNF Sequential Pattern Group
Participants receive neuromuscular electrical stimulation (NMES) followed by PNF sequential training with upper limb diagonal functional patterns (D1 and D2), including rhythmic initiation, dynamic reversals, repetitive contractions, and isotonic contractions with moderate resistance (8-12 repetitions per pattern over 20-30 minutes).
Interventions delivered three times per week for eight weeks.
|
Biphasic waveform NMES at 30-40Hz frequency with pulse duration of 200-300μs, producing comfortable but visible muscle contraction.
Applied to affected upper limb for 30 minutes per session, three times per week for eight weeks.
PNF sequential training with upper limb diagonal functional patterns (D1 and D2).
Techniques include rhythmic initiation, dynamic reversals, repetitive contractions, and combination of isotonic contractions with moderate resistance according to patient's capabilities.
Each session includes 8-12 repetitions per pattern over 20-30 minutes, three times per week for eight weeks.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Upper Limb Motor Function
大体时间：Baseline and 8 weeks (post-intervention)
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Fugl-Meyer Assessment for Upper Extremity (FMA-UE).
A standardized 66-point scale assessing motor recovery after stroke based on Brunnstrom stages.
Evaluates shoulder, elbow, wrist, hand, and coordination functions.
Higher scores indicate better motor function.
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Baseline and 8 weeks (post-intervention)
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Muscle Tone
大体时间：Baseline and 8 weeks (post-intervention)
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Modified Ashworth Scale (MAS).
A 5-point scale (0-4) measuring resistance during passive stretching of the affected upper limb muscles.
0 = normal tone; 4 = rigidity.
Assesses spasticity reduction.
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Baseline and 8 weeks (post-intervention)
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2026年1月1日
初级完成 (估计的)
2026年6月15日
研究完成 (估计的)
2026年7月15日
研究注册日期
首次提交
2026年5月23日
首先提交符合 QC 标准的
2026年5月23日
首次发布 (实际的)
2026年6月1日
研究记录更新
最后更新发布 (实际的)
2026年6月1日
上次提交的符合 QC 标准的更新
2026年5月23日
最后验证
2026年5月1日
更多信息
与本研究相关的术语
其他相关的 MeSH 术语
其他研究编号
- TUF/EIRB/ 220 /26
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
不
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