Effect of Progressive Muscle Relaxation and Diaphragmatic Breathing on Sleep Disturbances in Chemotherapy Patients (PMR & DB)
Effect of Progressive Muscle Relaxation and Diaphragmatic Breathing Techniques on Sleep Disturbances in Cancer Patients Undergoing Chemotherapy
研究概览
详细说明
Sleep disturbance is one of the most frequently reported symptoms among patients undergoing chemotherapy. Multiple factors contribute to impaired sleep in this population, including treatment-related side effects, psychological stress, fatigue, pain, and inflammatory responses associated with cancer and its treatment. Poor sleep quality may adversely affect treatment adherence, physical functioning, emotional health, and overall quality of life.
Non-pharmacological interventions have gained increasing attention as safe and cost-effective approaches for managing sleep disturbances in cancer patients. Progressive Muscle Relaxation is a technique that involves systematic contraction and relaxation of specific muscle groups to reduce physical tension and promote relaxation. Diaphragmatic Breathing focuses on slow, deep breathing using the diaphragm to enhance parasympathetic nervous system activity and reduce physiological arousal.
This study will employ a randomized controlled trial design. Eligible chemotherapy patients who meet the inclusion criteria will be randomly allocated to either an intervention group or a control group. Participants in the intervention group will receive a structured program consisting of Progressive Muscle Relaxation and Diaphragmatic Breathing exercises in addition to routine medical care. Participants in the control group will receive routine medical care only.
Sleep outcomes will be evaluated before and after the intervention period using the Pittsburgh Sleep Quality Index, sleep diary recordings, and wearable sleep monitoring devices. The findings of this study may provide evidence regarding the effectiveness of combined relaxation and breathing techniques as supportive interventions for improving sleep quality among patients undergoing chemotherapy.
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习联系方式
- 姓名：Haidy Ashem, Professor
- 电话号码：01099765185
- 邮箱：haidyjojo.hn@gmail.com
研究联系人备份
- 姓名：Nada Yousef, Lecturer
- 电话号码：01021527586
- 邮箱：dr.nada123.ny@gmail.com
学习地点
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Egypt
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Giza、Egypt、埃及、12613
- Faculty of Physical Therapy
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接触：
- Haidy Nady Ashem, Prof. Dr.
- 电话号码：20 1099765185
- 邮箱：haidyjojo.hn@gmail.com
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接触：
- Nada Mohamed Yousef, Dr.
- 电话号码：20 1021527585
- 邮箱：dr.nada123.ny@gmail.com
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首席研究员：
- Haidy Nady Ashem, Prof.Dr
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参与标准
资格标准
适合学习的年龄
- 成人
接受健康志愿者
描述
Inclusion Criteria:
• Aged between 40-60 years
- Both male and female patients
- Currently receiving at least the second cycle of chemotherapy
- Receiving chemotherapy protocols (Zhou et al., 2022)
- PSQI score > 5 at baseline indicating poor sleep quality
- BMI between 18.5 and 30
- Able to provide informed consent
Exclusion Criteria:
Diagnosed with sleep disorders unrelated to chemotherapy (e.g., obstructive sleep apnea)
- Current use of sleep medications or anti-anxiety drugs
- Diagnosed with major psychiatric conditions
- Cognitive impairment limiting understanding of instructions
- Severe cardiopulmonary comorbidities
- Recent participation in relaxation-based clinical trials
学习计划
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：并行分配
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：PMR and Diaphragmatic Breathing Group
Participants will receive Progressive Muscle Relaxation and Diaphragmatic Breathing exercises in addition to traditional medical treatment during the study period.
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Participants will receive a structured program of Progressive Muscle Relaxation and Diaphragmatic Breathing exercises in addition to traditional treatment .
The intervention is designed to promote relaxation, reduce physiological arousal, and improve sleep quality in patients undergoing chemotherapy.
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无干预：Traditional treatment group
Participants will receive traditional medical treatment only without the relaxation and breathing intervention program.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Sleep Quality
大体时间：Baseline (pre-intervention) and after 4 weeks of intervention (post-intervention)
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Assessment of sleep quality using the Pittsburgh Sleep Quality Index (PSQI).
The PSQI total score is measured in points and ranges from 0 to 21, with higher scores indicating poorer sleep quality.
A total score greater than 5 indicates clinically significant sleep disturbance.
A reduction in the PSQI score from baseline to post-intervention reflects an improvement in sleep quality.
Changes in PSQI scores will be used to evaluate the effect of Progressive Muscle Relaxation and Diaphragmatic Breathing exercises on sleep disturbances in patients undergoing chemotherapy.
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Baseline (pre-intervention) and after 4 weeks of intervention (post-intervention)
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Sleep Latency
大体时间：Baseline (pre-intervention) and after 4 weeks of intervention (post-intervention)
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Assessment of the time required to fall asleep, measured in minutes using sleep diary records and a wearable wristband sleep monitor.
A decrease in sleep latency reflects improvement in sleep initiation.
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Baseline (pre-intervention) and after 4 weeks of intervention (post-intervention)
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Sleep Efficiency
大体时间：Baseline (pre-intervention) and after 4 weeks of intervention (post-intervention)
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Assessment of sleep efficiency, measured as a percentage (%) of total time spent asleep relative to total time spent in bed, using sleep diary records and a wearable wristband sleep monitor.
Higher percentages indicate better sleep efficiency.
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Baseline (pre-intervention) and after 4 weeks of intervention (post-intervention)
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Total Sleep Time
大体时间：Baseline (pre-intervention) and after 4 weeks of intervention (post-intervention)
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Assessment of total sleep duration, measured in hours per night using sleep diary records and a wearable wristband sleep monitor.
An increase in total sleep time reflects improvement in sleep quantity.
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Baseline (pre-intervention) and after 4 weeks of intervention (post-intervention)
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Number of Nocturnal Awakenings
大体时间：Baseline (pre-intervention) and after 4 weeks of intervention (post-intervention)
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Assessment of the frequency of awakenings during the night, measured as the number of awakenings per night using sleep diary records and a wearable wristband sleep monitor.
A lower number of nocturnal awakenings indicates improved sleep continuity.
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Baseline (pre-intervention) and after 4 weeks of intervention (post-intervention)
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合作者和调查者
调查人员
- 首席研究员：Haidy Ashem, Professor、Cairo University
出版物和有用的链接
一般刊物
- Jerath R, Edry JW, Barnes VA, Jerath V. Physiology of long pranayamic breathing: neural respiratory elements may provide a mechanism that explains how slow deep breathing shifts the autonomic nervous system. Med Hypotheses. 2006;67(3):566-71. doi: 10.1016/j.mehy.2006.02.042. Epub 2006 Apr 18.
- Irwin MR. Why sleep is important for health: a psychoneuroimmunology perspective. Annu Rev Psychol. 2015 Jan 3;66:143-72. doi: 10.1146/annurev-psych-010213-115205. Epub 2014 Jul 21.
- Mustian, K. M., et al. (2017). Treatment of sleep disturbance in cancer patients. Journal of Clinical Oncology.
- Jacobson, E. (1938). Progressive Relaxation. University of Chicago Press.
研究记录日期
研究主要日期
学习开始 (估计的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他相关的 MeSH 术语
其他研究编号
- PMR-DB-2026
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IPD 计划说明
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