Training in Adults With Parkinson's Disease
Training on Respiratory Parameters in Older Adults With Parkinson's Disease
Patients with Parkinson's disease experience progressive deconditioning of the respiratory muscles, leading to weakness and potential ventilatory impairments. Evidence indicates that physical exercise positively affects these muscles in people with various clinical conditions. This study will evaluate the effects of multicomponent and resistance training on respiratory parameters and physical and functional capacities in individuals with Parkinson's disease. A total of 40 patients will be randomly allocated to two groups: 20 individuals in the multicomponent training group and 20 in the resistance training group. Both groups will undergo a three-month intervention with two sessions per week. All participants must continue standard pharmacological treatment for Parkinson's disease. Respiratory parameters will be assessed using respiratory pressure measurement and spirometry. Physical and functional capacities will be assessed using the Rikli and Jones test battery.
研究概览
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习联系方式
- 姓名:Amanda de Jesus L Researcher
- 电话号码:+55 91 985075007
- 邮箱:prof_amandalopes@outlook.com
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Hoehn and Yahr stages 1-3
- Physical and mental requirements,
- No history of exercise training in the preceding three months.
- Standard pharmacological treatment for PD throughout the 12-week study period.
Exclusion Criteria:
- Mini-Mental State Examination score <24
- Unstable cardiovascular disease or any other uncontrolled chronic condition
学习计划
研究是如何设计的?
设计细节
- 主要用途:支持治疗
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的:Aerobic training
The first group will undergo multicomponent training for three months, with two sessions per week |
Resistence training |
|
有源比较器:Resistance training
The second group will undergo resistance training for the same period |
Resistence training |
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Inspiratory pressure
大体时间:three weeks
|
Respiratory muscle strength will be assessed using a manovacuometer with a range of -300 to +300 cmH2O. Respiratory muscle strength during inspiration will be assessed. |
three weeks
|
|
Forced Vital Capacity
大体时间:three weeks
|
Forced vital capacity, expressed in liters, will be assessed based on the maximum volume of inspired air, which will be measured in liters using a spirometer |
three weeks
|
合作者和调查者
出版物和有用的链接
一般刊物
- Goetz CG, Tilley BC, Shaftman SR, Stebbins GT, Fahn S, Martinez-Martin P, Poewe W, Sampaio C, Stern MB, Dodel R, Dubois B, Holloway R, Jankovic J, Kulisevsky J, Lang AE, Lees A, Leurgans S, LeWitt PA, Nyenhuis D, Olanow CW, Rascol O, Schrag A, Teresi JA, van Hilten JJ, LaPelle N; Movement Disorder Society UPDRS Revision Task Force. Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results. Mov Disord. 2008 Nov 15;23(15):2129-70. doi: 10.1002/mds.22340.
- McMahon L, Blake C, Lennon O. A systematic review and meta-analysis of respiratory dysfunction in Parkinson's disease. Eur J Neurol. 2023 May;30(5):1481-1504. doi: 10.1111/ene.15743. Epub 2023 Mar 7.
- Bouaziz W, Lang PO, Schmitt E, Kaltenbach G, Geny B, Vogel T. Health benefits of multicomponent training programmes in seniors: a systematic review. Int J Clin Pract. 2016 Jul;70(7):520-36. doi: 10.1111/ijcp.12822. Epub 2016 Jun 13.
研究记录日期
研究主要日期
学习开始 (估计的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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