- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00907244
Arterial Spin Labeling Perfusion Magnetic Resonance (MR) Imaging in Pediatric Brain Tumors
October 26, 2012 updated by: Children's Hospital of Philadelphia
CHP-901:Arterial Spin Labeling Perfusion MR Imaging in Pediatric Brain Tumors
The purpose of this study is to get information regarding the usefulness and accuracy of this new magnetic resonance imaging (MRI) technique - termed arterial spin labeling (ASL) - in the diagnosis of pediatric brain tumors.
Study Overview
Status
Completed
Conditions
Detailed Description
The purpose of this study is to get information regarding the usefulness and accuracy of this new MRI technique - termed arterial spin labeling (ASL) - in the diagnosis of pediatric brain tumors.
This technique can non-invasively measure the blood flow to the brain during MRI examination.
Because aggressive brain tumors require new blood vessels and a high level of blood supply to support its growth, we believe the tumor blood flow measured using ASL is a reliable indicator of tumor grade.
This information may be useful for doctors to make treatment decisions and to monitor patients' response to treatment.
Study Type
Observational
Enrollment (Actual)
13
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Pennsylvania
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Philadelphia, Pennsylvania, United States, 19104
- The Children's Hospital of Philadelphia
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
No older than 18 years (Child, Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Patients between 0-18 years who are diagnosed with primary brain tumor, undergoing MRI for clinical purpose are eligible for the study.
Description
Inclusion Criteria:
- Age 0-18 years
- Primary brain tumor (newly diagnosed or recurrent) with measurable disease (at least 1cm2)
Exclusion Criteria:
- Patients with cardiac pacemaker or ferrous metal foreign bodies
- Patients with medical problems contradictive to receiving MRI scans.
- Patients requiring general anesthesia or sedation for their MRI scan.
- Patients with a history of cerebrovascular disorders (stroke, moya moya) that may alter cerebral perfusion.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Collaborators
Investigators
- Principal Investigator: Michael Fisher, M.D., Children's Hospital of Philadelphia
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
April 1, 2008
Primary Completion (Actual)
July 1, 2012
Study Completion (Actual)
July 1, 2012
Study Registration Dates
First Submitted
May 20, 2009
First Submitted That Met QC Criteria
May 21, 2009
First Posted (Estimate)
May 22, 2009
Study Record Updates
Last Update Posted (Estimate)
October 29, 2012
Last Update Submitted That Met QC Criteria
October 26, 2012
Last Verified
January 1, 2012
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- CHP 901 ASL
- 2008-4-5917 (Other Identifier: Children's Hospital of Philadelphia IRB)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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