- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01016158
Umbilical Cord Serum Eye Drops
November 18, 2009 updated by: Chonnam National University Hospital
In the present study, the investigators investigated the efficacy of umbilical cord serum eye drops for the treatment of patients with recurrent corneal erosions.
Group A were treated with 20% umbilical cord serum eye drops 3 to 4 times a day in addition to artificial tears, and group B were treated with artificial tears only.
Ophthalmic examinations including visual acuity measurement and slit lamp biomicroscopy were performed before and every month after treatment.
Recurrence was defined as the presence of clinical symptoms accompanied by epithelial defects in the cornea.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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-
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Gwang-Ju, Korea, Republic of
- Chonnam National University Hospital
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- patients with recurrent corneal erosions
Exclusion Criteria:
- none
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: umbilical cord serum eyedrops
patients with recurrent corneal erosions were treated with 20% umbilical cord serum eye drops 3 to 4 times a day in addition to artificial tears
|
20% umbilical cord serum eye drops 3 to 4 times a day
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Yoon KC, Im SK, Park YG, Jung YD, Yang SY, Choi J. Application of umbilical cord serum eyedrops for the treatment of dry eye syndrome. Cornea. 2006 Apr;25(3):268-72. doi: 10.1097/01.ico.0000183484.85636.b6.
- del Castillo JM, de la Casa JM, Sardina RC, Fernandez RM, Feijoo JG, Gomez AC, Rodero MM, Sanchez JG. Treatment of recurrent corneal erosions using autologous serum. Cornea. 2002 Nov;21(8):781-3. doi: 10.1097/00003226-200211000-00010.
- Yoon KC, You IC, Im SK, Jeong TS, Park YG, Choi J. Application of umbilical cord serum eyedrops for the treatment of neurotrophic keratitis. Ophthalmology. 2007 Sep;114(9):1637-42. doi: 10.1016/j.ophtha.2006.12.014. Epub 2007 Mar 26.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
April 1, 2006
Primary Completion (Actual)
April 1, 2009
Study Completion (Actual)
October 1, 2009
Study Registration Dates
First Submitted
November 18, 2009
First Submitted That Met QC Criteria
November 18, 2009
First Posted (Estimate)
November 19, 2009
Study Record Updates
Last Update Posted (Estimate)
November 19, 2009
Last Update Submitted That Met QC Criteria
November 18, 2009
Last Verified
November 1, 2009
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- I-2009-11-135
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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Clinical Trials on Umbilical cord serum eyedrops
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Thomas Jefferson UniversityLata Mangeshkar Hospital, NKP Salve Institute of Medical Sciences, Nagpur...CompletedHypoxic Ischemic Encephalopathy | Umbilical Cord MilkingIndia
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Xinhua Hospital, Shanghai Jiao Tong University...Shanghai First Maternity and Infant Hospital; Yangpu District Central Hospital...Completed
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Bundang CHA HospitalWithdrawn
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Eastern Virginia Medical SchoolCompletedPrematurityUnited States
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Acibadem UniversityCompletedCesarean Delivery | Delayed Separation of Umbilical CordTurkey
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Jubilee Mission Medical College and Research InstituteUnknownHypoxic-Ischemic EncephalopathyIndia
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R3 Stem CellNot yet recruitingStroke | Autoimmune Diseases | Kidney Diseases | Urologic Diseases | Renal Insufficiency | Arthritis | Renal Failure | Alzheimer Disease | Erectile Dysfunction | Cardiomyopathies | Pulmonary Disease | Neurologic Disorder | Orthopedic Disorder | COPD | Cardiac Event | CHF | Neuropathy;Peripheral
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Fondazione Poliambulanza Istituto OspedalieroCompleted
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