- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01059890
Cerebral Antibiotics Distribution After Acute Brain Injury
October 10, 2016 updated by: Poitiers University Hospital
The aim of the study is to explore the distribution of antibiotics in the brain after an acute brain injury because brain infections treatment is still an health care problem.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Actual)
18
Phase
- Phase 1
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Poitiers, France, 86021
- Poitiers University Hospital - 2 rue de la Milétrie - Réanimation chirugicale
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Acute brain injury
- Patient who receive an antibiotic for an infection or prophylaxy
- Glasgow coma score < 8
Exclusion Criteria:
- Age < 18 years old
- Pregnant woman
- HCV, HIV, HBV infection
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Cefotaxime
|
|
Experimental: Metrodinazole
|
|
Experimental: Ciprofloxacine
|
|
Experimental: Fosfocine
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
September 1, 2009
Primary Completion (Actual)
June 1, 2013
Study Registration Dates
First Submitted
January 29, 2010
First Submitted That Met QC Criteria
January 29, 2010
First Posted (Estimate)
February 1, 2010
Study Record Updates
Last Update Posted (Estimate)
October 11, 2016
Last Update Submitted That Met QC Criteria
October 10, 2016
Last Verified
October 1, 2016
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Brain Diseases
- Central Nervous System Diseases
- Nervous System Diseases
- Infections
- Wounds and Injuries
- Bacterial Infections and Mycoses
- Craniocerebral Trauma
- Trauma, Nervous System
- Brain Injuries
- Bacterial Infections
- Molecular Mechanisms of Pharmacological Action
- Anti-Infective Agents
- Enzyme Inhibitors
- Antineoplastic Agents
- Topoisomerase II Inhibitors
- Topoisomerase Inhibitors
- Anti-Bacterial Agents
- Cytochrome P-450 Enzyme Inhibitors
- Antiprotozoal Agents
- Antiparasitic Agents
- Cytochrome P-450 CYP1A2 Inhibitors
- Metronidazole
- Ciprofloxacin
- Cefotaxime
- Cefoxitin
Other Study ID Numbers
- A-BRAIN
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Brain Injury
-
Brent MaselThe Moody FoundationCompletedChronic Traumatic Brain InjuryUnited States
-
Toronto Rehabilitation InstituteCentre for Aging and Brain Health Innovation; Ontario Neurotrauma FoundationUnknownBrain Injuries, Traumatic | Brain Injury, Chronic | Brain Injury Traumatic Severe | Brain Injury Traumatic ModerateCanada
-
BrainScope Company, Inc.RecruitingTBI (Traumatic Brain Injury) | Concussion, Brain | MTBI - Mild Traumatic Brain Injury | Closed Head InjuryUnited States
-
University of TurkuTurku University Hospital; The Finnish Funding Agency for Technology and Innovation... and other collaboratorsCompletedBrain Injuries | TBI (Traumatic Brain Injury) | Brain Injuries, Traumatic | Traumatic Brain Injury | Injury, Brain, TraumaticFinland
-
University of Sao Paulo General HospitalUnknownTraumatic Brain Injury | Severe Brain Injury | Closed Traumatic Brain InjuryBrazil
-
Center for Vision Development, New Market, MarylandUnknownBrain Injuries | Brain Injuries, Traumatic | Traumatic Brain Injury | Brain Injury, Chronic | Injury, Brain, TraumaticUnited States
-
Queen Mary University of LondonCompleted
-
Fondazione per la Ricerca Ospedale MaggioreCompletedBrain Injuries, Traumatic | Brain Injury Traumatic Severe | Brain Injury Traumatic ModerateItaly
-
Assiut UniversityUnknown
-
Institut National de la Santé Et de la Recherche...Institut National de Recherche en Informatique et en AutomatiqueNot yet recruitingTBI (Traumatic Brain Injury)France
Clinical Trials on Metronidazole
-
University of Maryland, BaltimoreFood and Drug Administration (FDA)Completed
-
Mansoura UniversityCompletedAnal Fistula | Hemorrhoids | Anal FissureEgypt
-
PfizerForest LaboratoriesCompleted
-
Dr.dr.Irma Bernadette, SpKK (K)Science and Technology Park, Center of Innovation Technologies for Human...Not yet recruiting
-
Peking University Shenzhen HospitalCompletedRecurrence | Bacterial VaginosisChina
-
Peking University Shenzhen HospitalBGI, ChinaCompleted
-
Dr. Reddy's Laboratories LimitedReliance Clinical Research Services (Navi Mumbai, India)CompletedClostridium Difficile Associated DiarrheaIndia
-
Peking University Shenzhen HospitalBGI, ChinaRecruiting
-
bioRASI, LLCCompletedPapulopustular Rosacea | Erythematotelangiectatic RosaceaUnited States
-
University of Auckland, New ZealandCompletedPostoperative Pain | HemorrhoidsNew Zealand