GAT-DCT-Discordance Due to Corneal Properties

October 17, 2016 updated by: University of Zurich

Influence of Discordant Intraocular Eye Pressure Readings Taken by Dynamic Contour Tonometry and Goldmann Applanation Tonometry

IOP is measured with two devices (Dynamic Contour Tonometry (DCT) and Goldmann applanation tonometry (GAT)).

Study Overview

Status

Completed

Conditions

Glaucoma

Intervention / Treatment

Device: Intraocular Pressure Measurement

Detailed Description

DCT reading will be compared to a corrected GAT reading by the formula of Elsheikh, Alhasso and Pye.

Trial with medical device

Study Type

Observational

Enrollment (Actual)

112

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Switzerland
- ZH
  - Zurich, ZH, Switzerland, 8091
    - University Hospital Zurich, Ophthalmic Clinic

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

glaucoma patients

Description

Inclusion criteria:

clinical diagnosis of glaucoma

Exclusion criteria:

other optic neuropathy other then glaucoma
age<18
corneal surgery
use of contact lenses

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Intraocular pressure (IOP) Time Frame: IOP is measured at the only study visit	IOP is measured with goldman-applanation tonometer and dynamic-contour-tonometer at the only study visit (V0)	IOP is measured at the only study visit

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Demographical and clinical data Time Frame: study visit V0	Age, axial length of the eye, central corneal thickness	study visit V0

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Zurich

Investigators

Principal Investigator: Christoph Kniestedt, MD, University Hospital Zurich, Ophthalmic Clinic

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Wachtl J, Toteberg-Harms M, Frimmel S, Roos M, Kniestedt C. Correlation Between Dynamic Contour Tonometry, Uncorrected and Corrected Goldmann Applanation Tonometry, and Stage of Glaucoma. JAMA Ophthalmol. 2017 Jun 1;135(6):601-608. doi: 10.1001/jamaophthalmol.2017.1012.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

November 1, 2011

Primary Completion (ACTUAL)

September 1, 2016

Study Completion (ACTUAL)

October 1, 2016

Study Registration Dates

First Submitted

November 3, 2011

First Submitted That Met QC Criteria

November 14, 2011

First Posted (ESTIMATE)

November 17, 2011

Study Record Updates

Last Update Posted (ESTIMATE)

October 18, 2016

Last Update Submitted That Met QC Criteria

October 17, 2016

Last Verified