- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01695889
Is There a Relationship Between Previous Exposure to General Anesthesia and the Development of Alzheimer´s Disease? (DEMA)
March 24, 2016 updated by: Anna-Karin Strand, MD, University Hospital, Linkoeping
A Case-control Study of Exposure to General Anesthesia and a Diagnosis of Alzheimer´s Disease Later in Life.
The purpose of this study is to compare exposure to general anesthesia between cases with a diagnosis of Alzheimer´s disease and controls without diagnosis, through studies of medical records.
The investigators wish to explore if there is a relationship between exposure to general anesthesia and the development of Alzheimer´s disease.
Study Overview
Status
Unknown
Conditions
Study Type
Observational
Enrollment (Actual)
877
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Linkoping, Sweden, 58185
- University Hospital
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- ADULT
- OLDER_ADULT
- CHILD
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Cases from a regional Alzheimer´s disease record.
Matched controls from the national population register.
Description
Inclusion Criteria:
- Clinical diagnosis of Alzheimer´s disease
- Previous exposure to anesthesia
Exclusion Criteria:
- Inability to retrieve medical records
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Exposure to general anesthesia
Time Frame: Up to 20 years in retrospect
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Up to 20 years in retrospect
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Secondary Outcome Measures
Outcome Measure |
Time Frame |
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Exposure to inhaled anesthetics
Time Frame: Up to 20 years in retrospect
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Up to 20 years in retrospect
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Study Chair: Christina Eintrei, professor, University Hospital Linköping
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
May 1, 2012
Primary Completion (ANTICIPATED)
July 1, 2016
Study Completion (ANTICIPATED)
July 1, 2016
Study Registration Dates
First Submitted
September 27, 2012
First Submitted That Met QC Criteria
September 27, 2012
First Posted (ESTIMATE)
September 28, 2012
Study Record Updates
Last Update Posted (ESTIMATE)
March 25, 2016
Last Update Submitted That Met QC Criteria
March 24, 2016
Last Verified
March 1, 2016
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- DEMA-1
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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