The Effects of Low- and High-intensity Resistance Exercise on Force-velocity Characteristics in Older Adults

February 19, 2013 updated by: Universitaire Ziekenhuizen KU Leuven
The purpose of this study is to compare the impact of high- and low-intensity resistance exercise on force-velocity characteristics, muscle mass and inflammatory processes in older adults. As all training protocols are designed to end with maximal effort, effects are expected to be similar between groups.

Study Overview

Status

Completed

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

56

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

      • Leuven, Belgium, 3001
        • Faculty of Kinesiology and Rehabilitation Sciences

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

60 years to 80 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • age 60 to 80 years

Exclusion Criteria:

  • Knee or hip prothesis
  • Systematic training
  • Cardiovascular disease
  • Acute lower back pain
  • Dementia

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: High-load strength training
Active Comparator: Low-load strength training
Active Comparator: Low-load + moderate-load strength training

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Change in force-velocity characteristics of knee extensors
Time Frame: Baseline, 12weeks, 6 months
Baseline, 12weeks, 6 months

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in muscle volume
Time Frame: Baseline, 12weeks, 6 months
Baseline, 12weeks, 6 months
Change in maximal strength (one repetition maximum)
Time Frame: Baseline, 4weeks, 8weeks, 12weeks, 6 months
Strength is measured as the maximum weight on the training equipment that can be lifted only one time (= one repetition maximum).
Baseline, 4weeks, 8weeks, 12weeks, 6 months
Change in motivation
Time Frame: Baseline, every week for 12 weeks, 6 months
Baseline, every week for 12 weeks, 6 months
Change in physical activity
Time Frame: Baseline, 12weeks, 6 months
Baseline, 12weeks, 6 months
Change in inflammatory markers in blood
Time Frame: Baseline, 12weeks, 6 months
Baseline, 12weeks, 6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2012

Primary Completion (Actual)

December 1, 2012

Study Registration Dates

First Submitted

October 2, 2012

First Submitted That Met QC Criteria

October 12, 2012

First Posted (Estimate)

October 15, 2012

Study Record Updates

Last Update Posted (Estimate)

February 20, 2013

Last Update Submitted That Met QC Criteria

February 19, 2013

Last Verified

November 1, 2011

More Information

Terms related to this study

Other Study ID Numbers

  • S53709

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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