Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography (ATAC)

March 2, 2026 updated by: Sunil Srivastava, The Cleveland Clinic

Automated Analysis of Anterior Chamber Inflammation by Optical Coherence Tomography

A prospective, observational, case series investigating the feasibility of utilizing OCT scans of the anterior chamber of eyes with uveitis.

Study Overview

Status

Recruiting

Conditions

Study Type

Observational

Enrollment (Estimated)

1500

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

  • Name: Sunil K Srivastava, M.D.
  • Phone Number: 216-636-2286

Study Contact Backup

  • Name: Kimberly M Baynes, BSN, RN
  • Phone Number: 216-44-2566

Study Locations

  • United States
    • Ohio
      • Cleveland, Ohio, United States, 44195
        • Recruiting
        • Cole Eye Institute
        • Contact:
          • Sunil K Srivastava, M.D.
          • Phone Number: 216-636-2286
        • Contact:
          • Kimberly M Baynes, BSN,RN
          • Phone Number: 216-444-2566
        • Principal Investigator:
          • Sunil K Srivastava, M.D.

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Probability Sample

Study Population

Patients with inactive and active uveitis.

Description

Inclusion Criteria:

  • All patients presenting to Cole Eye Institute with uveitis.

Exclusion Criteria:

  • Inability to provide informed consent, including non-English speaking and cognitively/mentally impaired.
  • Severe corneal opacities preventing imaging of anterior chamber

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Use the OCT to objectively image and grade the degree of anterior chamber inflammation in eyes with inactive and active uveitis.
Time Frame: one year
one year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

The Cleveland Clinic

Investigators

  • Principal Investigator: Sunil K Srivastva, MD, The Cleveland Clinic

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

June 1, 2012

Primary Completion (Estimated)

June 1, 2028

Study Completion (Estimated)

June 1, 2029

Study Registration Dates

First Submitted

December 7, 2012

First Submitted That Met QC Criteria

December 10, 2012

First Posted (Estimated)

December 11, 2012

Study Record Updates

Last Update Posted (Actual)

March 4, 2026

Last Update Submitted That Met QC Criteria

March 2, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 12-612

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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