Registro Campania Salute Network on Hypertension (RCSN)
August 5, 2025 updated by: RAFFAELE IZZO, Federico II University
Registro Campania Salute Network for the Treatment of Hypertension and Correlated Diseases
The Registro Campania Salute Network (RCSN) is a prospective registry aimed at improving the management of essential hypertension by integrating the activity of general practitioners (GPs) with that of the hypertension specialist.
It involves selected GPs homogeneously allocated in the regional area, and the Hypertension Clinic of the Federico II University in Naples, which served as co-ordinating centre.
Through the RCSN system it is possible to store clinical data detected at each visit between the peripheral units and the co-ordinating centre and to support scientific analysis of the dataset.
Study Overview
Status
Recruiting
Conditions
Detailed Description
The patients will be followed over a period of twenty years and all clinical data will be recorded in order to investigate the role of hypertension and correlated disease on this patient population
Study Type
Observational
Enrollment (Estimated)
10000
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Bruno Trimarco, MD
- Phone Number: +390817462250
- Email: trimarco@unina.it
Study Contact Backup
- Name: eugenio Stabile, MD
- Phone Number: +393316776019
- Email: eugeniostabile@gmail.com
Study Locations
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-
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Napoli, Italy, 80131
- Recruiting
- Department od advanced biomedical sciences, Università degli studi di Napoli Federico II, Via sergio Pansini 5
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Contact:
- eugenio Stabile, MD
- Phone Number: +393316776019
- Email: eugeniostabile@gmail.com
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Contact:
- Raffaele Izzo, MD
- Phone Number: +390817462211
- Email: rafizzo@unina.it
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Principal Investigator:
- Bruno Trimarco, MD
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 85 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Sampling Method
Probability Sample
Study Population
Hypertensive patients
Description
Inclusion Criteria:
-Hypertension
- 18 years old
Exclusion Criteria:
- Refused to sign informed consent
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
MACCE
Time Frame: every year up to 20 years
|
Major adverse cardiac and cerebrovascular events
|
every year up to 20 years
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Bruno Trimarco, MD, Dipartimento di Scienze Biomediche Avanzate, Università degli Studi di Napoli Federico II
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Stabile E, Franzese M, Chianese S, Alfani A, Gerardi D, Colaiori I, Annunziata M, Nappi P, Scalise M, Di Serafino L, Puzone B, Avvedimento M, Leone A, Ilardi F, Piccolo R, Franzone A, Cirillo P, Morisco C, Trimarco B, Esposito G. Predictors of adherence to composite therapy after acute coronary syndromes. J Cardiovasc Med (Hagerstown). 2021 Aug 1;22(8):645-651. doi: 10.2459/JCM.0000000000001201.
- Mancusi C, Losi MA, Albano G, De Stefano G, Morisco C, Barbato E, Trimarco B, De Luca N, de Simone G, Izzo R. Characteristics and Outcomes of Patients Presenting With Hypertensive Urgency in the Office Setting: The Campania Salute Network. Am J Hypertens. 2020 Apr 29;33(5):414-421. doi: 10.1093/ajh/hpaa003.
- Canciello G, Mancusi C, Losi MA, Izzo R, Trimarco B, de Simone G, De Luca N. Aortic Root Dilatation Is Associated With Incident Cardiovascular Events in a Population of Treated Hypertensive Patients: The Campania Salute Network. Am J Hypertens. 2018 Nov 13;31(12):1317-1323. doi: 10.1093/ajh/hpy113.
- Mancusi C, Izzo R, Ferrara LA, Rozza F, Losi MA, Canciello G, Pepe M, de Luca N, Trimarco B, de Simone G. Is increased uric acid a risk factor or a defensive response? The Campania Salute Network. Nutr Metab Cardiovasc Dis. 2018 Aug;28(8):839-846. doi: 10.1016/j.numecd.2018.04.013. Epub 2018 May 4.
- Izzo R, Losi MA, Stabile E, Lonnebakken MT, Canciello G, Esposito G, Barbato E, De Luca N, Trimarco B, de Simone G. Development of Left Ventricular Hypertrophy in Treated Hypertensive Outpatients: The Campania Salute Network. Hypertension. 2017 Jan;69(1):136-142. doi: 10.1161/HYPERTENSIONAHA.116.08158. Epub 2016 Nov 28.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
February 1, 2014
Primary Completion (Actual)
March 1, 2017
Study Completion (Estimated)
April 1, 2030
Study Registration Dates
First Submitted
April 8, 2014
First Submitted That Met QC Criteria
August 6, 2014
First Posted (Estimated)
August 7, 2014
Study Record Updates
Last Update Posted (Actual)
August 8, 2025
Last Update Submitted That Met QC Criteria
August 5, 2025
Last Verified
August 1, 2025
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 16/14
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.