Effects of Hydrocortisone on Social Cognition and Memory (CORT-COG)

June 18, 2015 updated by: Katja Wingenfeld, Charite University, Berlin, Germany

Effekte Von Hydrocortison Auf Soziale Kognition Und Gedächtnis Unter Berücksichtigung Von Geschlechtereffekten

The effects of hydrocortisone on cognition will be investigated.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

80 healthy young individuals (40 females and 40 male) will be recruited an randomized to either placebo or 10 mg hydrocortisone before testing. Tasks will on emotion recognition, memory and cognitive flexibilty will be conducted.

Study Type

Interventional

Enrollment (Actual)

80

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
      • Berlin, Germany
        • Charité University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

16 years to 28 years (Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • age 18 - 30
  • medication free

Exclusion Criteria:

  • any medication
  • severe ilness

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Hydrocortisone
10 mg hydrocortisone
Other: Hydrocortisone
Effects of hydrocortisone compared to placebo on cognition
Placebo Comparator: Placebo
1 pill Placebo
Other: Hydrocortisone
Effects of hydrocortisone compared to placebo on cognition

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
social cognition
Time Frame: 25 min
computer based test: Multifaceted Empaty test
25 min

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
memory
Time Frame: 25 min
autobiographic memory test (AMT)
25 min
cognitive flexibilty
Time Frame: 10 min
computer based test: task switch
10 min

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Charite University, Berlin, Germany

Investigators

  • Principal Investigator: Katja Wingenfeld, Charité University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

September 1, 2014

Primary Completion (Actual)

May 1, 2015

Study Completion (Actual)

May 1, 2015

Study Registration Dates

First Submitted

June 11, 2015

First Submitted That Met QC Criteria

June 18, 2015

First Posted (Estimate)

June 23, 2015

Study Record Updates

Last Update Posted (Estimate)

June 23, 2015

Last Update Submitted That Met QC Criteria

June 18, 2015

Last Verified

June 1, 2015

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • WI-CO-1

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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