- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03834246
Smoke Inhalation Injury in Patients Admitted to Intensive Care (fumeintox)
Prognostic Factors for Smoke Inhalation Injury in Patients Admitted to Intensive Care
Many Studies have shown that the smoke-inhalation injury is responsible for a high mortality mainly related to the systemic effects of carbon monoxide and cyanide. Respiratory lesions induced by smoke inhalation, is one of predictive factors of mortality.
The aim of the study is to identify the clinical and epidemiological characteristics of smoke-inhalation injury and to identify prognostic factors among these patients .
Study Overview
Status
Conditions
Detailed Description
The study is a monocentric, retrospective, descriptive and analytical study , betwen december 1997 and september 2018 in intensive care unit of university of hospital.
All patients aged over 18 year and who had received a diagnosis of smoke- inhalation injury and were admitted to the ICU of Medical University Hospital , a referral center in Paris providing HBO therapy , were potentially eligible for inclusion in this investigation.
Criteria used for recommending HBO therapy to a patient with transient or prolonged unconsciousness, abnormal neurologic findings on physical examination.
Data were analyzed to identify independent factors that may influence mortality.
Study Type
Enrollment (Anticipated)
Contacts and Locations
Study Contact
- Name: Rania BOUNAB, Dr
- Phone Number: +33 (1) 74 10 7778
- Email: rania.bounab@aphp.fr
Study Contact Backup
- Name: Fatima IZEDAREN, CRA
- Phone Number: +33 (1) 47 10 44 49
- Email: fatima.izedaren@aphp.fr
Study Locations
-
-
-
Garches, France, 92380
- Recruiting
- Raymond Poincaré
-
Contact:
- Rania BOUNAB
- Phone Number: 0698258796
- Email: rania.bounab@aphp.fr
-
Contact:
- rania Bounab
- Phone Number: 0147107778
- Email: rania.bounab@aphp.fr
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria
- Men or women over the age of 18
- Hyperbaric oxygen therapy between 1997 and 2018
Exclusion Criteria
- Patients under 18 years old.
- Patient opposed to the use of his data
- Patients not treated with hyperbaric oxygen
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
mortality rate
Time Frame: 20 years
|
survival study for the search of prognostic factors
|
20 years
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
epidemiologic characteritics
Time Frame: 20 years
|
description of quantitative and qualitative data
|
20 years
|
Collaborators and Investigators
Investigators
- Principal Investigator: Rania BOUNAB, dr, Raymond Poincaré Hospital
Publications and helpful links
General Publications
- Darling GE, Keresteci MA, Ibanez D, Pugash RA, Peters WJ, Neligan PC. Pulmonary complications in inhalation injuries with associated cutaneous burn. J Trauma. 1996 Jan;40(1):83-9. doi: 10.1097/00005373-199601000-00016.
- You K, Yang HT, Kym D, Yoon J, HaejunYim, Cho YS, Hur J, Chun W, Kim JH. Inhalation injury in burn patients: establishing the link between diagnosis and prognosis. Burns. 2014 Dec;40(8):1470-5. doi: 10.1016/j.burns.2014.09.015. Epub 2014 Oct 16.
- Kim Y, Kym D, Hur J, Yoon J, Yim H, Cho YS, Chun W. Does inhalation injury predict mortality in burns patients or require redefinition? PLoS One. 2017 Sep 27;12(9):e0185195. doi: 10.1371/journal.pone.0185195. eCollection 2017.
- Liao WC, Cheng WC, Wu BR, Chen WC, Chen CY, Chen CH, Tu CY, Hsia TC. Outcome and prognostic factors of patients treated in the intensive care unit for carbon monoxide poisoning. J Formos Med Assoc. 2019 Apr;118(4):821-827. doi: 10.1016/j.jfma.2018.09.005. Epub 2018 Oct 5.
- Raphael JC, Annane D, Chevret S. Hyperbaric oxygen for acute carbon monoxide poisoning. N Engl J Med. 2003 Feb 6;348(6):557-60; author reply 557-60. No abstract available.
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- Cicit805
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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