Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With CVD (Lp(a)HORIZON)

A Randomized Double-blind, Placebo-controlled, Multicenter Trial Assessing the Impact of Lipoprotein (a) Lowering With Pelacarsen (TQJ230) on Major Cardiovascular Events in Patients With Established Cardiovascular Disease

This is a pivotal phase 3 study designed to support an indication for the reduction of cardiovascular risk in patients with established CVD and elevated Lp(a)

Study Overview

• Status: Active, not recruiting
• Conditions: Cardiovascular Disease and Lipoprotein(a)
• Intervention / Treatment: Drug: TQJ230; Drug: Placebo

• Study Type: Interventional
• Enrollment (Actual): 8323
• Phase: Phase 3

Expanded Access

Available outside the clinical trial. See expanded access record.

Contacts and Locations

Study Locations

• Argentina
  • Caba, Argentina, C1426
    • Novartis Investigative Site
  • Capital Federal, Argentina, C1023AAB
    • Novartis Investigative Site
  • Corrientes, Argentina, W3400CDS
    • Novartis Investigative Site
  • Córdoba, Argentina, X5002
    • Novartis Investigative Site
  • San Luis, Argentina, D5702JRS
    • Novartis Investigative Site
  • Buenos Aires
    • CABA, Buenos Aires, Argentina, 1407
      • Novartis Investigative Site
    • CABA, Buenos Aires, Argentina, C1056ABI
      • Novartis Investigative Site
    • CABA, Buenos Aires, Argentina, 1280
      • Novartis Investigative Site
    • CABA, Buenos Aires, Argentina, 1426
      • Novartis Investigative Site
    • Mar del Plata, Buenos Aires, Argentina, 7600
      • Novartis Investigative Site
    • Ramos Mejía, Buenos Aires, Argentina, B1704ETD
      • Novartis Investigative Site
  • Córdoba Province
    • Córdoba, Córdoba Province, Argentina, 5000
      • Novartis Investigative Site
  • San Miguel de Tucuman
    • San Miguel de Tucumán, San Miguel de Tucuman, Argentina, T4000ICL
      • Novartis Investigative Site
  • Santa Fe Province
    • Rosario, Santa Fe Province, Argentina, 2000
      • Novartis Investigative Site
    • Rosario, Santa Fe Province, Argentina, S200CVD
      • Novartis Investigative Site
    • Santa Fe, Santa Fe Province, Argentina, S3000FWO
      • Novartis Investigative Site
  • Tucumán Province
    • San Miguel Tucuman, Tucumán Province, Argentina, T4000IFL
      • Novartis Investigative Site
• Australia
  • Liverpool, Australia, 2170
    • Novartis Investigative Site
  • New South Wales
    • Camperdown, New South Wales, Australia, 2050
      • Novartis Investigative Site
  • Queensland
    • Chemside, Queensland, Australia, 4032
      • Novartis Investigative Site
    • Southport, Queensland, Australia, 4215
      • Novartis Investigative Site
    • Woolloongabba, Queensland, Australia, 4102
      • Novartis Investigative Site
  • Victoria
    • Clayton, Victoria, Australia, 3168
      • Novartis Investigative Site
  • Western Australia
    • Perth, Western Australia, Australia, 6000
      • Novartis Investigative Site
• Austria
  • Graz, Austria, 8036
    • Novartis Investigative Site
  • Innsbruck, Austria, 6020
    • Novartis Investigative Site
  • Linz, Austria, 4021
    • Novartis Investigative Site
  • Salzburg, Austria, 5020
    • Novartis Investigative Site
  • Vienna, Austria, 1090
    • Novartis Investigative Site
  • Vienna, Austria, 1210
    • Novartis Investigative Site
• Belgium
  • Bruges, Belgium, 8000
    • Novartis Investigative Site
  • Dendermonde, Belgium, 9200
    • Novartis Investigative Site
  • Huy, Belgium, 4500
    • Novartis Investigative Site
  • Mechelen, Belgium, 2800
    • Novartis Investigative Site
  • Brussels Capital
    • Brussels, Brussels Capital, Belgium, 1070
      • Novartis Investigative Site
  • Limburg
    • Genk, Limburg, Belgium, 3600
      • Novartis Investigative Site
  • Oost Vlaanderen
    • Aalst, Oost Vlaanderen, Belgium, 9300
      • Novartis Investigative Site
  • West-Vlaanderen
    • Kortrijk, West-Vlaanderen, Belgium, 8500
      • Novartis Investigative Site
• Brazil
  • Rio de Janeiro, Brazil, 20241-180
    • Novartis Investigative Site
  • Alagoas
    • Maceió, Alagoas, Brazil, 57051-160
      • Novartis Investigative Site
  • Espírito Santo
    • Vitória, Espírito Santo, Brazil, 29055-450
      • Novartis Investigative Site
  • Estado de Bahia
    • Salvador, Estado de Bahia, Brazil, 40170-130
      • Novartis Investigative Site
  • Federal District
    • Brasília, Federal District, Brazil, 70390-700
      • Novartis Investigative Site
  • Goiás
    • Goiânia, Goiás, Brazil, 74605-020
      • Novartis Investigative Site
  • Minas Gerais
    • Belo Horizonte, Minas Gerais, Brazil, 30150-270
      • Novartis Investigative Site
    • Belo Horizonte, Minas Gerais, Brazil, 30220-330
      • Novartis Investigative Site
    • Juiz de Fora, Minas Gerais, Brazil, 36033-318
      • Novartis Investigative Site
    • Uberlândia, Minas Gerais, Brazil, 38400 500
      • Novartis Investigative Site
  • Paraná
    • Curitiba, Paraná, Brazil, 80730-150
      • Novartis Investigative Site
    • Curitiba, Paraná, Brazil, 80230-130
      • Novartis Investigative Site
  • Rio Grande do Sul
    • Canoas, Rio Grande do Sul, Brazil, 92425 900
      • Novartis Investigative Site
    • Porto Alegre, Rio Grande do Sul, Brazil, 90880-480
      • Novartis Investigative Site
    • Porto Alegre, Rio Grande do Sul, Brazil, 90160-093
      • Novartis Investigative Site
  • Santa Catarina
    • Blumenau, Santa Catarina, Brazil, 89020-430
      • Novartis Investigative Site
  • Sergipe
    • Aracaju, Sergipe, Brazil, 49055-530
      • Novartis Investigative Site
  • São Paulo
    • Campinas, São Paulo, Brazil, 13060 080
      • Novartis Investigative Site
    • Campinas, São Paulo, Brazil, 13092133
      • Novartis Investigative Site
    • Ribeirão Preto, São Paulo, Brazil, 14026-020
      • Novartis Investigative Site
    • Santo André, São Paulo, Brazil, 09060-870
      • Novartis Investigative Site
    • Santo André, São Paulo, Brazil, 09090-790
      • Novartis Investigative Site
    • Sao Jose Rio Preto, São Paulo, Brazil, 15090 000
      • Novartis Investigative Site
    • Sao Jose Rio Preto, São Paulo, Brazil, 15015-750
      • Novartis Investigative Site
    • São Paulo, São Paulo, Brazil, 04005-003
      • Novartis Investigative Site
    • São Paulo, São Paulo, Brazil, 04266 010
      • Novartis Investigative Site
    • São Paulo, São Paulo, Brazil, 05403 000
      • Novartis Investigative Site
    • São Paulo, São Paulo, Brazil, 01323 000
      • Novartis Investigative Site
    • São Paulo, São Paulo, Brazil, 04023-900
      • Novartis Investigative Site
    • São Paulo, São Paulo, Brazil, 05403-900
      • Novartis Investigative Site
• Bulgaria
  • Burgas, Bulgaria, 8001
    • Novartis Investigative Site
  • Pernik, Bulgaria, 2300
    • Novartis Investigative Site
  • Pleven, Bulgaria, 5800
    • Novartis Investigative Site
  • Plovdiv, Bulgaria, 4000
    • Novartis Investigative Site
  • Rousse, Bulgaria, 7002
    • Novartis Investigative Site
  • Sofia, Bulgaria, 1233
    • Novartis Investigative Site
  • Sofia, Bulgaria, 1750
    • Novartis Investigative Site
  • Bulgaria
    • Blagoevgrad, Bulgaria, Bulgaria, 2700
      • Novartis Investigative Site
• Canada
  • British Columbia
    • Vancouver, British Columbia, Canada, V6Z 1Y6
      • Novartis Investigative Site
    • Vancouver, British Columbia, Canada, V5Z 1M9
      • Novartis Investigative Site
    • Victoria, British Columbia, Canada, V8R4R2
      • Novartis Investigative Site
    • Victoria, British Columbia, Canada, V8T 5G4
      • Novartis Investigative Site
  • Ontario
    • Oakville, Ontario, Canada, L6K 3W7
      • Novartis Investigative Site
    • Toronto, Ontario, Canada, M9V 4B4
      • Novartis Investigative Site
  • Quebec
    • Lévis, Quebec, Canada, G6V 4Z5
      • Novartis Investigative Site
    • Montreal, Quebec, Canada, H4A 3J1
      • Novartis Investigative Site
    • Montreal, Quebec, Canada, H3T 1E2
      • Novartis Investigative Site
    • Montreal, Quebec, Canada, H1T 1C8
      • Novartis Investigative Site
    • Montreal, Quebec, Canada, H2X 1R9
      • Novartis Investigative Site
    • Québec, Quebec, Canada, G1R 2J6
      • Novartis Investigative Site
    • Québec, Quebec, Canada, G1V 4W2
      • Novartis Investigative Site
    • Québec, Quebec, Canada, G1V 4G2
      • Novartis Investigative Site
    • Québec, Quebec, Canada, G1V 4G5
      • Novartis Investigative Site
    • Terrebonne, Quebec, Canada, J6V 2H2
      • Novartis Investigative Site
• Chile
  • Santiago, Chile, 7500710
    • Novartis Investigative Site
  • Santiago, Chile, 8380456
    • Novartis Investigative Site
  • RM
    • Santiago, RM, Chile, 7500588
      • Novartis Investigative Site
  • Santiago Metropolitan
    • Santiago, Santiago Metropolitan, Chile, 8331143
      • Novartis Investigative Site
    • Santiago, Santiago Metropolitan, Chile, 7500710
      • Novartis Investigative Site
    • Santiago, Santiago Metropolitan, Chile, 8380465
      • Novartis Investigative Site
• China
  • Beijing, China, 100730
    • Novartis Investigative Site
  • Beijing, China, 100050
    • Novartis Investigative Site
  • Beijing, China, 100191
    • Novartis Investigative Site
  • Shanghai, China, 200025
    • Novartis Investigative Site
  • Shanghai, China, 200040
    • Novartis Investigative Site
  • Shanghai, China, 200120
    • Novartis Investigative Site
  • Shanghai, China, 200065
    • Novartis Investigative Site
  • Tianjin, China, 300052
    • Novartis Investigative Site
  • Tianjin, China, 300121
    • Novartis Investigative Site
  • Tianjin, China, 030045
    • Novartis Investigative Site
  • Xiamen, China, 361004
    • Novartis Investigative Site
  • Beijing Municipality
    • Beijing, Beijing Municipality, China, 100013
      • Novartis Investigative Site
  • Gansu
    • Lanzhou, Gansu, China, 730030
      • Novartis Investigative Site
  • Guangdong
    • Foshan, Guangdong, China, 528000
      • Novartis Investigative Site
    • Guangzhou, Guangdong, China, 510080
      • Novartis Investigative Site
    • Guangzhou, Guangdong, China, 510030
      • Novartis Investigative Site
  • Heilongjiang
    • Harbin, Heilongjiang, China, 150000
      • Novartis Investigative Site
  • Hunan
    • Changsha, Hunan, China, 410008
      • Novartis Investigative Site
    • Changsha, Hunan, China, 410011
      • Novartis Investigative Site
    • Changsha, Hunan, China, 410003
      • Novartis Investigative Site
  • Inner Mongolia
    • Baotou, Inner Mongolia, China, 014040
      • Novartis Investigative Site
  • Jiangsu
    • Nanjing, Jiangsu, China, 210029
      • Novartis Investigative Site
    • Nanjing, Jiangsu, China, 210009
      • Novartis Investigative Site
    • Nanjing, Jiangsu, China, 211166
      • Novartis Investigative Site
    • Suzhou, Jiangsu, China, 215004
      • Novartis Investigative Site
    • Xuzhou, Jiangsu, China, 221003
      • Novartis Investigative Site
  • Jilin
    • Changchun, Jilin, China, 130021
      • Novartis Investigative Site
  • Liaoning
    • Dalian, Liaoning, China, 116011
      • Novartis Investigative Site
    • Shenyang, Liaoning, China, 110016
      • Novartis Investigative Site
    • Shenyang, Liaoning, China, 110004
      • Novartis Investigative Site
  • Shandong
    • Jinan, Shandong, China, 250013
      • Novartis Investigative Site
  • Shanxi
    • Xian, Shanxi, China, 710061
      • Novartis Investigative Site
  • Sichuan
    • Chengdu, Sichuan, China, 610041
      • Novartis Investigative Site
  • Xinjiang
    • Ürümqi, Xinjiang, China, 830054
      • Novartis Investigative Site
  • Zhejiang
    • Hangzhou, Zhejiang, China, 310016
      • Novartis Investigative Site
    • Hangzhou, Zhejiang, China, 310014
      • Novartis Investigative Site
    • Wenzhou, Zhejiang, China, 325000
      • Novartis Investigative Site
• Colombia
  • Bogotá, Colombia, 111211
    • Novartis Investigative Site
  • Medellín, Colombia, 050037
    • Novartis Investigative Site
  • San Gil, Colombia, 684031
    • Novartis Investigative Site
  • Antioquia
    • Medellín, Antioquia, Colombia, 050001
      • Novartis Investigative Site
  • Colombia
    • Barranquilla, Colombia, Colombia, 080020
      • Novartis Investigative Site
  • Santander Department
    • Bucaramanga, Santander Department, Colombia, 681017
      • Novartis Investigative Site
  • Valle del Cauca Department
    • Cali, Valle del Cauca Department, Colombia, 760001
      • Novartis Investigative Site
    • Cali, Valle del Cauca Department, Colombia, 760032
      • Novartis Investigative Site
• Czechia
  • Brandýs nad Labem, Czechia, 250 01
    • Novartis Investigative Site
  • Brno, Czechia, 625 00
    • Novartis Investigative Site
  • Brno, Czechia, 602 00
    • Novartis Investigative Site
  • Broumov, Czechia, 550 01
    • Novartis Investigative Site
  • CZE, Czechia, 110 00
    • Novartis Investigative Site
  • Hlučín, Czechia, 748 01
    • Novartis Investigative Site
  • Hodonín, Czechia, 695 01
    • Novartis Investigative Site
  • Jihlava, Czechia, 586 01
    • Novartis Investigative Site
  • Kolín, Czechia, 280 20
    • Novartis Investigative Site
  • Liberec, Czechia, 460 01
    • Novartis Investigative Site
  • Liberec, Czechia, 460 05
    • Novartis Investigative Site
  • Mariánské Lázně, Czechia, 353 01
    • Novartis Investigative Site
  • Most, Czechia, 434 01
    • Novartis Investigative Site
  • Mělník, Czechia, 276 01
    • Novartis Investigative Site
  • Olomouc, Czechia, 779 00
    • Novartis Investigative Site
  • Ostrava, Czechia, 700 30
    • Novartis Investigative Site
  • Ostrava, Czechia, 710 00
    • Novartis Investigative Site
  • Pardubice, Czechia, 532 03
    • Novartis Investigative Site
  • Polička, Czechia, 57201
    • Novartis Investigative Site
  • Prague, Czechia, 128 08
    • Novartis Investigative Site
  • Prague, Czechia, 158 00
    • Novartis Investigative Site
  • Prague, Czechia, 101 00
    • Novartis Investigative Site
  • Prague, Czechia, 110 00
    • Novartis Investigative Site
  • Přerov, Czechia, 751 52
    • Novartis Investigative Site
  • Slaný, Czechia, 274 01
    • Novartis Investigative Site
  • Svitavy, Czechia, 568 25
    • Novartis Investigative Site
  • Trutnov, Czechia, 460 63
    • Novartis Investigative Site
  • Třebíč, Czechia, 674 01
    • Novartis Investigative Site
  • Uherské Hradiště, Czechia, 686 01
    • Novartis Investigative Site
  • Valašské Meziříčí, Czechia, 75742
    • Novartis Investigative Site
  • Zlín, Czechia, 760 01
    • Novartis Investigative Site
  • Český Krumlov, Czechia, 381 01
    • Novartis Investigative Site
  • Chlumec Nad Cidlinou
    • Chlumec nad Cidlinou, Chlumec Nad Cidlinou, Czechia, 503 51
      • Novartis Investigative Site
  • Czech Republic
    • Kroměříž, Czech Republic, Czechia, 767 55
      • Novartis Investigative Site
    • Louny, Czech Republic, Czechia, 440 01
      • Novartis Investigative Site
    • Ostrava, Czech Republic, Czechia, 725 27
      • Novartis Investigative Site
    • Ústí nad Labem, Czech Republic, Czechia, 400 01
      • Novartis Investigative Site
  • Zabreh
    • Ostrava, Zabreh, Czechia, 700 30
      • Novartis Investigative Site
• Denmark
  • Aarhus N, Denmark, 8200
    • Novartis Investigative Site
  • Copenhagen, Denmark, DK-2100
    • Novartis Investigative Site
  • Esbjerg, Denmark, 6700
    • Novartis Investigative Site
  • Gistrup, Denmark, 9260
    • Novartis Investigative Site
  • Herlev, Denmark, DK-2730
    • Novartis Investigative Site
  • Roskilde, Denmark, 4000
    • Novartis Investigative Site
  • Viborg, Denmark, 8800
    • Novartis Investigative Site
• France
  • Bron, France, 69677
    • Novartis Investigative Site
  • Chambray-lès-Tours, France, 37170
    • Novartis Investigative Site
  • Compiègne, France, 60321
    • Novartis Investigative Site
  • Grenoble, France, 38043
    • Novartis Investigative Site
  • Le Coudray, France, 28630
    • Novartis Investigative Site
  • Lille, France, 59000
    • Novartis Investigative Site
  • Nantes, France, 44093
    • Novartis Investigative Site
  • Paris, France, 75015
    • Novartis Investigative Site
  • Paris, France, 75012
    • Novartis Investigative Site
  • Paris, France, 75018
    • Novartis Investigative Site
  • Toulouse, France, 31054
    • Novartis Investigative Site
  • Tourcoing, France, 59208
    • Novartis Investigative Site
  • Valenciennes, France, 59300
    • Novartis Investigative Site
• Germany
  • Aachen, Germany, 52074
    • Novartis Investigative Site
  • Bad Homburg, Germany, 61348
    • Novartis Investigative Site
  • Bad Krozingen, Germany, 79189
    • Novartis Investigative Site
  • Bad Oeynhausen, Germany, 32545
    • Novartis Investigative Site
  • Bamberg, Germany, 96049
    • Novartis Investigative Site
  • Berlin, Germany, 10367
    • Novartis Investigative Site
  • Berlin, Germany, 13353
    • Novartis Investigative Site
  • Berlin, Germany, 10787
    • Novartis Investigative Site
  • Berlin, Germany, 10789
    • Novartis Investigative Site
  • Berlin, Germany, 13347
    • Novartis Investigative Site
  • Berlin, Germany, 10559
    • Novartis Investigative Site
  • Bielefeld, Germany, 33604
    • Novartis Investigative Site
  • Chemnitz, Germany, 09122
    • Novartis Investigative Site
  • Dessau, Germany, 06846
    • Novartis Investigative Site
  • Dortmund, Germany, 44137
    • Novartis Investigative Site
  • Dresden, Germany, 01307
    • Novartis Investigative Site
  • Dresden, Germany, 01277
    • Novartis Investigative Site
  • Dresden, Germany, 01069
    • Novartis Investigative Site
  • Essen, Germany, 45277
    • Novartis Investigative Site
  • Essen, Germany, 45355
    • Novartis Investigative Site
  • Essen, Germany, 45359
    • Novartis Investigative Site
  • Gelnhausen, Germany, 63571
    • Novartis Investigative Site
  • Hamburg, Germany, 22041
    • Novartis Investigative Site
  • Hamburg, Germany, 22607
    • Novartis Investigative Site
  • Kassel, Germany, 34121
    • Novartis Investigative Site
  • Lüneburg, Germany, 21339
    • Novartis Investigative Site
  • Magdeburg, Germany, 39120
    • Novartis Investigative Site
  • Mannheim, Germany, 68165
    • Novartis Investigative Site
  • Meissen, Germany, 01662
    • Novartis Investigative Site
  • München, Germany, 80636
    • Novartis Investigative Site
  • Münster, Germany, 48149
    • Novartis Investigative Site
  • Potsdam, Germany, 14471
    • Novartis Investigative Site
  • Rüdersdorf, Germany, 15562
    • Novartis Investigative Site
  • Ulm, Germany, 89077
    • Novartis Investigative Site
  • Warendorf, Germany, 48231
    • Novartis Investigative Site
  • Baden-Wurttemberg
    • Mannheim, Baden-Wurttemberg, Germany, 68305
      • Novartis Investigative Site
  • Bavaria
    • Künzing, Bavaria, Germany, 94550
      • Novartis Investigative Site
    • Muehldorf Am Inn, Bavaria, Germany, 84453
      • Novartis Investigative Site
    • Munich, Bavaria, Germany, 81377
      • Novartis Investigative Site
    • Weiden in Der Oberpfalz, Bavaria, Germany, 92637
      • Novartis Investigative Site
  • Hesse
    • Frankfurt am Main, Hesse, Germany, 60590
      • Novartis Investigative Site
    • Frankfurt am Main, Hesse, Germany, 60594
      • Novartis Investigative Site
  • Lower Saxony
    • Hanover, Lower Saxony, Germany, 30159
      • Novartis Investigative Site
  • North Rhine-Westphalia
    • Cologne, North Rhine-Westphalia, Germany, 50937
      • Novartis Investigative Site
    • Cologne, North Rhine-Westphalia, Germany, 50733
      • Novartis Investigative Site
    • Essen, North Rhine-Westphalia, Germany, 45355
      • Novartis Investigative Site
    • Löhne, North Rhine-Westphalia, Germany, 32584
      • Novartis Investigative Site
  • Saarland
    • Saint Ingbert, Saarland, Germany, 66386
      • Novartis Investigative Site
  • Saxony
    • Chemnitz, Saxony, Germany, 09113
      • Novartis Investigative Site
    • Dresden, Saxony, Germany, 01307
      • Novartis Investigative Site
    • Dresden, Saxony, Germany, 01099
      • Novartis Investigative Site
    • Leipzig, Saxony, Germany, 04103
      • Novartis Investigative Site
    • Leipzig, Saxony, Germany, 04107
      • Novartis Investigative Site
  • Saxony-Anhalt
    • Wittenberg, Saxony-Anhalt, Germany, 06886
      • Novartis Investigative Site
  • Thuringia
    • Jena, Thuringia, Germany, 07740
      • Novartis Investigative Site
• Greece
  • Athens, Greece, 115 27
    • Novartis Investigative Site
  • Athens, Greece, 115 21
    • Novartis Investigative Site
  • Athens, Greece, 142 33
    • Novartis Investigative Site
  • Chalcis, Greece, 341 00
    • Novartis Investigative Site
  • Ioannina, Greece, 455 00
    • Novartis Investigative Site
  • Larissa, Greece, 411 10
    • Novartis Investigative Site
  • Thessaloniki, Greece, 54636
    • Novartis Investigative Site
• Guatemala
  • Guatemala City, Guatemala, 01010
    • Novartis Investigative Site
  • Guatemala City, Guatemala, 01011
    • Novartis Investigative Site
  • Departamento de Guatemala
    • Guatemala City, Departamento de Guatemala, Guatemala, 01001
      • Novartis Investigative Site
• Hong Kong
  • Hong Kong, Hong Kong, 999077
    • Novartis Investigative Site
  • Shatin, Hong Kong, 999077
    • Novartis Investigative Site
• Hungary
  • Baja, Hungary, 6500
    • Novartis Investigative Site
  • Budapest, Hungary, H-1083
    • Novartis Investigative Site
  • Budapest, Hungary, H-1097
    • Novartis Investigative Site
  • Budapest, Hungary, 1204
    • Novartis Investigative Site
  • Budapest, Hungary, H-1145
    • Novartis Investigative Site
  • Kistarcsa, Hungary, 2143
    • Novartis Investigative Site
  • Makó, Hungary, 6900
    • Novartis Investigative Site
  • Miskolc, Hungary, 3526
    • Novartis Investigative Site
  • Nyíregyháza, Hungary, 4400
    • Novartis Investigative Site
  • Szeged, Hungary, 6725
    • Novartis Investigative Site
  • Székesfehérvár, Hungary, H-8000
    • Novartis Investigative Site
  • Baranya
    • Pécs, Baranya, Hungary, 7623
      • Novartis Investigative Site
  • Hajdu Bihar Megye
    • Debrecen, Hajdu Bihar Megye, Hungary, 4032
      • Novartis Investigative Site
• Iceland
  • Kopavogur, Iceland, 201
    • Novartis Investigative Site
  • Reykjavik, Iceland, 101
    • Novartis Investigative Site
• India
  • New Delhi, India, 110025
    • Novartis Investigative Site
  • Andhra Pradesh
    • Guntur, Andhra Pradesh, India, 522001
      • Novartis Investigative Site
    • Hyderabad, Andhra Pradesh, India, 500033
      • Novartis Investigative Site
  • Gujarat
    • Ahmedabad, Gujarat, India, 380054
      • Novartis Investigative Site
    • Ahmedabad, Gujarat, India, 380060
      • Novartis Investigative Site
    • Vadodara, Gujarat, India, 390022
      • Novartis Investigative Site
  • Karnataka
    • Belagavi, Karnataka, India, 590010
      • Novartis Investigative Site
    • Mangalore, Karnataka, India, 575018
      • Novartis Investigative Site
    • Manipal, Karnataka, India, 576104
      • Novartis Investigative Site
    • Mysore, Karnataka, India, 570015
      • Novartis Investigative Site
  • Kerala
    • Kochi, Kerala, India, 682027
      • Novartis Investigative Site
    • Kochi, Kerala, India, 682041
      • Novartis Investigative Site
    • Kochi, Kerala, India, 682018
      • Novartis Investigative Site
    • Kozhikode, Kerala, India, 673008
      • Novartis Investigative Site
  • Maharashtra
    • Mumbai, Maharashtra, India, 401107
      • Novartis Investigative Site
    • Nagpur, Maharashtra, India, 440009
      • Novartis Investigative Site
    • Nagpur, Maharashtra, India, 440008
      • Novartis Investigative Site
    • Nagpur, Maharashtra, India, 440012
      • Novartis Investigative Site
    • Nagpur, Maharashtra, India, 440033
      • Novartis Investigative Site
    • Nashik, Maharashtra, India, 422005
      • Novartis Investigative Site
    • Pune, Maharashtra, India, 411004
      • Novartis Investigative Site
    • Pune, Maharashtra, India, 411001
      • Novartis Investigative Site
    • Pune, Maharashtra, India, 411045
      • Novartis Investigative Site
  • National Capital Territory of Delhi
    • New Delhi, National Capital Territory of Delhi, India, 110060
      • Novartis Investigative Site
    • New Delhi, National Capital Territory of Delhi, India, 110075
      • Novartis Investigative Site
  • Rajasthan
    • Bikaner, Rajasthan, India, 334003
      • Novartis Investigative Site
  • Tamil Nadu
    • Chennai, Tamil Nadu, India, 600006
      • Novartis Investigative Site
    • Coimbatore, Tamil Nadu, India, 641037
      • Novartis Investigative Site
    • Coimbatore, Tamil Nadu, India, 641009
      • Novartis Investigative Site
  • Telangana
    • Hyderabad, Telangana, India, 500082
      • Novartis Investigative Site
    • Hyderabad, Telangana, India, 500034
      • Novartis Investigative Site
    • Secunderabad, Telangana, India, 500003
      • Novartis Investigative Site
  • Uttar Pradesh
    • Ghaziabad, Uttar Pradesh, India, 201012
      • Novartis Investigative Site
    • Lucknow, Uttar Pradesh, India, 226003
      • Novartis Investigative Site
    • Varanasi, Uttar Pradesh, India, 221010
      • Novartis Investigative Site
  • Uttarakhand
    • Dehradun, Uttarakhand, India, 248001
      • Novartis Investigative Site
• Israel
  • Beersheba, Israel, 8457108
    • Novartis Investigative Site
  • Haifa, Israel, 3436212
    • Novartis Investigative Site
  • Haifa, Israel, 3104802
    • Novartis Investigative Site
  • Holon, Israel, 5822012
    • Novartis Investigative Site
  • Jerusalem, Israel, 9112001
    • Novartis Investigative Site
  • Petah Tikva, Israel, 4941492
    • Novartis Investigative Site
  • Ramat Gan, Israel, 5265601
    • Novartis Investigative Site
• Italy
  • Naples, Italy, 80131
    • Novartis Investigative Site
  • AN
    • Ancona, AN, Italy, 60128
      • Novartis Investigative Site
  • BG
    • Bergamo, BG, Italy, 24127
      • Novartis Investigative Site
  • BO
    • Bologna, BO, Italy, 40138
      • Novartis Investigative Site
  • BS
    • Brescia, BS, Italy, 25123
      • Novartis Investigative Site
  • FE
    • Cona, FE, Italy, 44124
      • Novartis Investigative Site
  • FI
    • Florence, FI, Italy, 50134
      • Novartis Investigative Site
  • IS
    • Pozzilli, IS, Italy, 86077
      • Novartis Investigative Site
  • MI
    • Milan, MI, Italy, 20162
      • Novartis Investigative Site
    • Milan, MI, Italy, 20132
      • Novartis Investigative Site
    • Milan, MI, Italy, 20138
      • Novartis Investigative Site
    • Milan, MI, Italy, 20149
      • Novartis Investigative Site
    • Rozzano, MI, Italy, 20089
      • Novartis Investigative Site
  • PA
    • Palermo, PA, Italy, 90127
      • Novartis Investigative Site
  • PG
    • Perugia, PG, Italy, 06129
      • Novartis Investigative Site
  • PI
    • Pisa, PI, Italy, 56124
      • Novartis Investigative Site
    • Pisa, PI, Italy, 56126
      • Novartis Investigative Site
  • RM
    • Roma, RM, Italy, 00161
      • Novartis Investigative Site
    • Roma, RM, Italy, 00189
      • Novartis Investigative Site
  • SA
    • Salerno, SA, Italy, 84131
      • Novartis Investigative Site
  • VA
    • Varese, VA, Italy, 21100
      • Novartis Investigative Site
• Japan
  • Ishikawa, Japan, 9208641
    • Novartis Investigative Site
  • Aichi-ken
    • Nagoya, Aichi-ken, Japan, 453-8511
      • Novartis Investigative Site
    • Seto, Aichi-ken, Japan, 4898642
      • Novartis Investigative Site
  • Aomori
    • Hirosaki, Aomori, Japan, 0368563
      • Novartis Investigative Site
  • Chiba
    • Asahi, Chiba, Japan, 289-2511
      • Novartis Investigative Site
    • Funabashi, Chiba, Japan, 273-8588
      • Novartis Investigative Site
    • Matsudo, Chiba, Japan, 270-2251
      • Novartis Investigative Site
  • Fukuoka
    • Fukuoka, Fukuoka, Japan, 8140180
      • Novartis Investigative Site
    • Kitakyushu, Fukuoka, Japan, 8028555
      • Novartis Investigative Site
  • Gifu
    • Ōgaki, Gifu, Japan, 503-8502
      • Novartis Investigative Site
  • Hiroshima
    • Kure, Hiroshima, Japan, 737-0023
      • Novartis Investigative Site
  • Ibaraki
    • Tsuchiura, Ibaraki, Japan, 300-0028
      • Novartis Investigative Site
  • Ishikawa-ken
    • Kahoku-gun, Ishikawa-ken, Japan, 920-0293
      • Novartis Investigative Site
    • Komatsu, Ishikawa-ken, Japan, 923-0961
      • Novartis Investigative Site
  • Kagawa-ken
    • Takamatsu, Kagawa-ken, Japan, 7608557
      • Novartis Investigative Site
  • Kanagawa
    • Kawasaki, Kanagawa, Japan, 2120021
      • Novartis Investigative Site
    • Sagamihara, Kanagawa, Japan, 252-0375
      • Novartis Investigative Site
    • Yokohama, Kanagawa, Japan, 232-0024
      • Novartis Investigative Site
    • Yokohama, Kanagawa, Japan, 2360037
      • Novartis Investigative Site
  • Miyagi
    • Sendai, Miyagi, Japan, 981-0914
      • Novartis Investigative Site
  • Miyazaki
    • Miyhazaki, Miyazaki, Japan, 8802102
      • Novartis Investigative Site
  • Niigata
    • Nagaoka, Niigata, Japan, 940-8621
      • Novartis Investigative Site
  • Osaka
    • Osaka, Osaka, Japan, 543-8922
      • Novartis Investigative Site
    • Osaka, Osaka, Japan, 5300001
      • Novartis Investigative Site
  • Saitama
    • Kawaguchi, Saitama, Japan, 3330842
      • Novartis Investigative Site
    • Sayama, Saitama, Japan, 350-1305
      • Novartis Investigative Site
  • Shiga
    • Ōmihachiman, Shiga, Japan, 523-0082
      • Novartis Investigative Site
  • Tokyo
    • Bunkyo Ku, Tokyo, Japan, 1138431
      • Novartis Investigative Site
    • Chuo Ku, Tokyo, Japan, 104-8560
      • Novartis Investigative Site
    • Chuo-ku, Tokyo, Japan, 1030027
      • Novartis Investigative Site
    • Hachiōji, Tokyo, Japan, 192-0918
      • Novartis Investigative Site
    • Itabashi-ku, Tokyo, Japan, 1738610
      • Novartis Investigative Site
    • Shinagawa-ku, Tokyo, Japan, 1428666
      • Novartis Investigative Site
    • Toshima-ku, Tokyo, Japan, 171-0014
      • Novartis Investigative Site
    • Ōta-ku, Tokyo, Japan, 1438541
      • Novartis Investigative Site
• Mexico
  • Culiacan Sinaloa, Mexico, 80230
    • Novartis Investigative Site
  • Distrito Federal, Mexico, 14080
    • Novartis Investigative Site
  • Aguascalientes
    • Aguascalientes, Aguascalientes, Mexico, 20230
      • Novartis Investigative Site
  • Morelos
    • Cuernavaca, Morelos, Mexico, 62250
      • Novartis Investigative Site
  • San Luis Potosí
    • San Luis Potosí City, San Luis Potosí, Mexico, 78200
      • Novartis Investigative Site
• Netherlands
  • Amersfoort, Netherlands, 3813 TZ
    • Novartis Investigative Site
  • Enschede, Netherlands, 7512KZ
    • Novartis Investigative Site
  • Gouda, Netherlands, 2803 HH
    • Novartis Investigative Site
  • Hardenberg, Netherlands, 7770 SE
    • Novartis Investigative Site
  • Utrecht, Netherlands, 3584 CX
    • Novartis Investigative Site
  • Venlo, Netherlands, 5912 BL
    • Novartis Investigative Site
  • Gelderland
    • Apeldoorn, Gelderland, Netherlands, 7334 DZ
      • Novartis Investigative Site
    • Arnhem, Gelderland, Netherlands, 6815 AD
      • Novartis Investigative Site
    • Nijmegen, Gelderland, Netherlands, 6500HB
      • Novartis Investigative Site
    • Tiel, Gelderland, Netherlands, 4002 WP
      • Novartis Investigative Site
  • Gerlderland
    • Nijmegen, Gerlderland, Netherlands, 6532 SZ
      • Novartis Investigative Site
  • Limburg
    • Heerlen, Limburg, Netherlands, 6419 PC
      • Novartis Investigative Site
  • North Brabant
    • Tilburg, North Brabant, Netherlands, 5042 AD
      • Novartis Investigative Site
  • North Holland
    • Alkmaar, North Holland, Netherlands, 1815 JD
      • Novartis Investigative Site
    • Amsterdam, North Holland, Netherlands, 1090 HM
      • Novartis Investigative Site
    • Amsterdam, North Holland, Netherlands, 1105 AZ
      • Novartis Investigative Site
    • Heemstede, North Holland, Netherlands, 2035 RC
      • Novartis Investigative Site
  • Overijssel
    • Deventer, Overijssel, Netherlands, 7416 SE
      • Novartis Investigative Site
    • Zwolle, Overijssel, Netherlands, 8025 AB
      • Novartis Investigative Site
  • Provincie Friesland
    • Sneek, Provincie Friesland, Netherlands, 8601 ZK
      • Novartis Investigative Site
  • Provincie Groningen
    • Groningen, Provincie Groningen, Netherlands, 9728 NZ
      • Novartis Investigative Site
  • South Holland
    • Delft, South Holland, Netherlands, 2625 AD
      • Novartis Investigative Site
    • Leiden, South Holland, Netherlands, 2333 ZA
      • Novartis Investigative Site
    • Leiderdorp, South Holland, Netherlands, 2353 GA
      • Novartis Investigative Site
    • The Hague, South Holland, Netherlands, 2545 AA
      • Novartis Investigative Site
• Norway
  • Oslo, Norway, 0514
    • Novartis Investigative Site
  • Skedsmokorset, Norway, 2020
    • Novartis Investigative Site
• Peru
  • Lima region
    • San Miguel, Lima region, Peru, 32
      • Novartis Investigative Site
• Poland
  • Bielsko-Biala, Poland, 43-316
    • Novartis Investigative Site
  • Chrzanów, Poland, 32-500
    • Novartis Investigative Site
  • Gdansk, Poland, 80-214
    • Novartis Investigative Site
  • Gdynia, Poland, 81-157
    • Novartis Investigative Site
  • Krakow, Poland, 30-082
    • Novartis Investigative Site
  • Krakow, Poland, 31-216
    • Novartis Investigative Site
  • Kędzierzyn-Koźle, Poland, 47 220
    • Novartis Investigative Site
  • Lodz, Poland, 93-338
    • Novartis Investigative Site
  • Lodz, Poland, 91-347
    • Novartis Investigative Site
  • Poznan, Poland, 60-589
    • Novartis Investigative Site
  • Sochaczew, Poland, 96-500
    • Novartis Investigative Site
  • Tarnów, Poland, 33-100
    • Novartis Investigative Site
• Portugal
  • Coimbra, Portugal, 3004-561
    • Novartis Investigative Site
  • Guimarães, Portugal, 4835-044
    • Novartis Investigative Site
  • Setúbal, Portugal, 2910-549
    • Novartis Investigative Site
• Puerto Rico
  • Ponce, Puerto Rico, 00717-1322
    • Novartis Investigative Site
  • Ponce, Puerto Rico, 00717-1322
    • Research and Cardiovascular Corp
• Romania
  • Brasov, Romania, 500283
    • Novartis Investigative Site
  • Bucharest, Romania, 050098
    • Novartis Investigative Site
  • Bucharest, Romania, 010192
    • Novartis Investigative Site
  • Iași, Romania, 700503
    • Novartis Investigative Site
  • Buzău
    • Buzău, Buzău, Romania, 120133
      • Novartis Investigative Site
  • Dolj
    • Craiova, Dolj, Romania, 200513
      • Novartis Investigative Site
  • Jud Iasi
    • Iași, Jud Iasi, Romania, 700732
      • Novartis Investigative Site
  • Maramureş
    • Baia Mare, Maramureş, Romania, 430222
      • Novartis Investigative Site
    • Baia Mare, Maramureş, Romania, 430123
      • Novartis Investigative Site
  • Timiș County
    • Timișoara, Timiș County, Romania, 300362
      • Novartis Investigative Site
• Russia
  • Chelyabinsk, Russia, 454047
    • Novartis Investigative Site
  • Ivanovo, Russia, 153012
    • Novartis Investigative Site
  • Izhevsk, Russia, 426061
    • Novartis Investigative Site
  • Kemerovo, Russia, 650002
    • Novartis Investigative Site
  • Kirov, Russia, 610035
    • Novartis Investigative Site
  • Krasnodar, Russia, 350086
    • Novartis Investigative Site
  • Moscow, Russia, 117997
    • Novartis Investigative Site
  • Moscow, Russia, 117198
    • Novartis Investigative Site
  • Moscow, Russia, 127473
    • Novartis Investigative Site
  • Moscow, Russia, 101990
    • Novartis Investigative Site
  • Moscow, Russia, 121552
    • Novartis Investigative Site
  • Moscow, Russia, 141060
    • Novartis Investigative Site
  • Moscow, Russia, 143420
    • Novartis Investigative Site
  • Novosibirsk, Russia, 630090
    • Novartis Investigative Site
  • Perm, Russia, 614097
    • Novartis Investigative Site
  • Petrozavodsk, Russia, 185019
    • Novartis Investigative Site
  • Rostov-on-Don, Russia, 344022
    • Novartis Investigative Site
  • Ryazan, Russia, 390039
    • Novartis Investigative Site
  • Saint Petersburg, Russia, 197341
    • Novartis Investigative Site
  • Saint Petersburg, Russia, 195197
    • Novartis Investigative Site
  • Saint Petersburg, Russia, 197110
    • Novartis Investigative Site
  • Saint Petersburg, Russia, 191015
    • Novartis Investigative Site
  • Saint Petersburg, Russia, 192007
    • Novartis Investigative Site
  • Saint Petersburg, Russia, 194354
    • Novartis Investigative Site
  • Saint Petersburg, Russia, 196143
    • Novartis Investigative Site
  • Saint Petersburg, Russia, 197136
    • Novartis Investigative Site
  • Samara, Russia, 443070
    • Novartis Investigative Site
  • Saratov, Russia, 410012
    • Novartis Investigative Site
  • Saratov, Russia, 410028
    • Novartis Investigative Site
  • Sochy, Russia, 354002
    • Novartis Investigative Site
  • Tomsk, Russia, 634009
    • Novartis Investigative Site
  • Ulyanovsk, Russia, 432063
    • Novartis Investigative Site
  • Vsevolozhsk, Russia, 188643
    • Novartis Investigative Site
  • Yaroslavl, Russia, 150062
    • Novartis Investigative Site
  • Yekaterinburg, Russia, 620144
    • Novartis Investigative Site
  • Yekaterinburg, Russia, 620028
    • Novartis Investigative Site
  • Yekaterinburg, Russia, 620137
    • Novartis Investigative Site
  • Russia
    • Saint Petersburg, Russia, Russia, 195197
      • Novartis Investigative Site
    • Saint Petersburg, Russia, Russia, 198328
      • Novartis Investigative Site
• Slovakia
  • Banská Bystrica, Slovakia, 974 05
    • Novartis Investigative Site
  • Bardejov, Slovakia, 085 01
    • Novartis Investigative Site
  • Bratislava, Slovakia, 833 48
    • Novartis Investigative Site
  • Bratislava, Slovakia, 821 07
    • Novartis Investigative Site
  • Bratislava, Slovakia, 833 05
    • Novartis Investigative Site
  • Bratislava, Slovakia, 851 07
    • Novartis Investigative Site
  • Bratislava, Slovakia, 851 01
    • Novartis Investigative Site
  • Bratislava, Slovakia, 841 08
    • Novartis Investigative Site
  • Dolný Kubín, Slovakia, 026 01
    • Novartis Investigative Site
  • Handlová, Slovakia, 972 51
    • Novartis Investigative Site
  • Kláštor pod Znievom, Slovakia, 038 43
    • Novartis Investigative Site
  • Komárno, Slovakia, 945 01
    • Novartis Investigative Site
  • Komárno, Slovakia, 945 05
    • Novartis Investigative Site
  • Košice, Slovakia, 040 01
    • Novartis Investigative Site
  • Košice, Slovakia, 040 22
    • Novartis Investigative Site
  • Lučenec, Slovakia, 984 01
    • Novartis Investigative Site
  • Nitra, Slovakia, 949 01
    • Novartis Investigative Site
  • Nitra, Slovakia, 950 01
    • Novartis Investigative Site
  • Nitra, Slovakia, 949 11
    • Novartis Investigative Site
  • Nové Zámky, Slovakia, 940 01
    • Novartis Investigative Site
  • Nové Zámky, Slovakia, 940 02
    • Novartis Investigative Site
  • Piešťany, Slovakia, 921 01
    • Novartis Investigative Site
  • Považská Bystrica, Slovakia, 017 01
    • Novartis Investigative Site
  • Prešov, Slovakia, 080 01
    • Novartis Investigative Site
  • Rimavská Sobota, Slovakia, 979 01
    • Novartis Investigative Site
  • Rožňava, Slovakia, 048 01
    • Novartis Investigative Site
  • Svidník, Slovakia, 089 01
    • Novartis Investigative Site
  • Žilina, Slovakia, 010 01
    • Novartis Investigative Site
  • Slovakia
    • Brezno, Slovakia, Slovakia, 977 01
      • Novartis Investigative Site
    • Košice, Slovakia, Slovakia, 040 01
      • Novartis Investigative Site
    • Trnava, Slovakia, Slovakia, 917 02
      • Novartis Investigative Site
• Slovenia
  • Ljubljana, Slovenia, 1000
    • Novartis Investigative Site
• South Africa
  • Cape Town, South Africa, 6665
    • Novartis Investigative Site
  • Gauteng
    • Soweto, Gauteng, South Africa, 2013
      • Novartis Investigative Site
  • Western Cape
    • Cape Town, Western Cape, South Africa, 7500
      • Novartis Investigative Site
    • Cape Town, Western Cape, South Africa, 7925
      • Novartis Investigative Site
    • George, Western Cape, South Africa, 6529
      • Novartis Investigative Site
• South Korea
  • Busan, South Korea, 49201
    • Novartis Investigative Site
  • Gwangju, South Korea, 61469
    • Novartis Investigative Site
  • Seoul, South Korea, 03181
    • Novartis Investigative Site
  • Seoul, South Korea, 06591
    • Novartis Investigative Site
  • Dalseo gu
    • Daegu, Dalseo gu, South Korea, 42602
      • Novartis Investigative Site
  • Gangwon-do
    • Wŏnju, Gangwon-do, South Korea, 26426
      • Novartis Investigative Site
  • Gyeonggi-do
    • Bundang Gu, Gyeonggi-do, South Korea, 13620
      • Novartis Investigative Site
    • Suwon, Gyeonggi-do, South Korea, 16499
      • Novartis Investigative Site
  • Korea
    • Incheon, Korea, South Korea, 405 760
      • Novartis Investigative Site
    • Seoul, Korea, South Korea, 08308
      • Novartis Investigative Site
    • Seoul, Korea, South Korea, 02841
      • Novartis Investigative Site
  • Seoul
    • Seoul, Seoul, South Korea, 03080
      • Novartis Investigative Site
• Spain
  • A Coruña, Spain, 15001
    • Novartis Investigative Site
  • Barcelona, Spain, 08036
    • Novartis Investigative Site
  • Barcelona, Spain, 08025
    • Novartis Investigative Site
  • Córdoba, Spain, 14004
    • Novartis Investigative Site
  • Huelva, Spain, 21080
    • Novartis Investigative Site
  • Madrid, Spain, 28041
    • Novartis Investigative Site
  • Madrid, Spain, 28040
    • Novartis Investigative Site
  • Málaga, Spain, 29010
    • Novartis Investigative Site
  • Seville, Spain, 41009
    • Novartis Investigative Site
  • Seville, Spain, 41013
    • Novartis Investigative Site
  • Valencia, Spain, 46010
    • Novartis Investigative Site
  • Zaragoza, Spain, 50009
    • Novartis Investigative Site
  • A Coruna
    • Santiago Compostela, A Coruna, Spain, 15706
      • Novartis Investigative Site
  • Andalusia
    • Seville, Andalusia, Spain, 41014
      • Novartis Investigative Site
  • Barcelona
    • Badalona, Barcelona, Spain, 08916
      • Novartis Investigative Site
    • L'Hospitalet de Llobregat, Barcelona, Spain, 08907
      • Novartis Investigative Site
  • Cantabria
    • Santander, Cantabria, Spain, 39008
      • Novartis Investigative Site
  • Extremadura
    • Cáceres, Extremadura, Spain, 10003
      • Novartis Investigative Site
  • Tarragona
    • Reus, Tarragona, Spain, 43201
      • Novartis Investigative Site
• Sweden
  • Gothenburg, Sweden, 413 46
    • Novartis Investigative Site
  • Lund, Sweden, 222 21
    • Novartis Investigative Site
  • Stockholm, Sweden, 14186
    • Novartis Investigative Site
• Switzerland
  • Basel, Switzerland, 4031
    • Novartis Investigative Site
  • Bern, Switzerland, 3010
    • Novartis Investigative Site
  • Geneva, Switzerland, 1211
    • Novartis Investigative Site
  • Lausanne, Switzerland, 1011
    • Novartis Investigative Site
  • Liestal, Switzerland, 4410
    • Novartis Investigative Site
  • Zurich, Switzerland, 8091
    • Novartis Investigative Site
• Taiwan
  • Hsinchu, Taiwan, 30069
    • Novartis Investigative Site
  • Kaohsiung City, Taiwan, 83301
    • Novartis Investigative Site
  • Kaohsiung City, Taiwan, 80756
    • Novartis Investigative Site
  • Keelung, Taiwan, 20401
    • Novartis Investigative Site
  • Tainan, Taiwan, 71004
    • Novartis Investigative Site
  • Taipei, Taiwan, 11217
    • Novartis Investigative Site
  • Taoyuan, Taiwan, 33305
    • Novartis Investigative Site
  • Yilan, Taiwan, 26058
    • Novartis Investigative Site
  • Taiwan ROC
    • Taichung, Taiwan ROC, Taiwan, 40201
      • Novartis Investigative Site
• Turkey (Türkiye)
  • Izmir, Turkey (Türkiye), 35100
    • Novartis Investigative Site
  • Balcova
    • Izmir, Balcova, Turkey (Türkiye), 35340
      • Novartis Investigative Site
  • Bilkent-Cankaya
    • Ankara, Bilkent-Cankaya, Turkey (Türkiye), 06800
      • Novartis Investigative Site
  • Fatih
    • Istanbul, Fatih, Turkey (Türkiye), 34098
      • Novartis Investigative Site
  • Ilkadim
    • Samsun, Ilkadim, Turkey (Türkiye), 55090
      • Novartis Investigative Site
  • Kadikoy
    • Istanbul, Kadikoy, Turkey (Türkiye), 34668
      • Novartis Investigative Site
  • Odunpazari
    • Eskişehir, Odunpazari, Turkey (Türkiye), 26040
      • Novartis Investigative Site
  • Samsun
    • Samsun, Samsun, Turkey (Türkiye), 55080
      • Novartis Investigative Site
  • Yenisehir
    • Mersin, Yenisehir, Turkey (Türkiye), 33110
      • Novartis Investigative Site
• United Kingdom
  • Birmingham, United Kingdom, B9 5SS
    • Novartis Investigative Site
  • Bournemouth, United Kingdom, BH7 7DW
    • Novartis Investigative Site
  • Bristol, United Kingdom, BS2 8HW
    • Novartis Investigative Site
  • Bromwich, United Kingdom, B71 4HJ
    • Novartis Investigative Site
  • Cardiff, United Kingdom, CF64 2XX
    • Novartis Investigative Site
  • Chesterfield, United Kingdom, S40 4AA
    • Novartis Investigative Site
  • Dundee, United Kingdom, DD1 9SY
    • Novartis Investigative Site
  • Edinburgh, United Kingdom, EH16 4SA
    • Novartis Investigative Site
  • Glasgow, United Kingdom, G20 7BE
    • Novartis Investigative Site
  • Leicester, United Kingdom, LE3 9QP
    • Novartis Investigative Site
  • Liverpool, United Kingdom, L7 8XP
    • Novartis Investigative Site
  • London, United Kingdom, W12 0HS
    • Novartis Investigative Site
  • Londonderry, United Kingdom, BT47 6SB
    • Novartis Investigative Site
  • Manchester, United Kingdom, M13 9WL
    • Novartis Investigative Site
  • Middlesbrough, United Kingdom, TS4 3BW
    • Novartis Investigative Site
  • Middlesex, United Kingdom, UB9 6JH
    • Novartis Investigative Site
  • Newport, United Kingdom, NP20 2UB
    • Novartis Investigative Site
  • Norwich, United Kingdom, NR4 7UY
    • Novartis Investigative Site
  • Plymouth, United Kingdom, PL6 8DH
    • Novartis Investigative Site
  • Rhyl, United Kingdom, LL18 5UJ
    • Novartis Investigative Site
  • Sheffield, United Kingdom, S5 7AU
    • Novartis Investigative Site
  • Swansea, United Kingdom, SA2 8QA
    • Novartis Investigative Site
  • Tyne and Wear, United Kingdom, NE29 8NH
    • Novartis Investigative Site
  • Wiltshire, United Kingdom, SN15 2SB
    • Novartis Investigative Site
  • Wrexham, United Kingdom, LL13 7TD
    • Novartis Investigative Site
  • Dorset
    • Dorchester, Dorset, United Kingdom, DT1 2JY
      • Novartis Investigative Site
  • GBR
    • London, GBR, United Kingdom, EC1M 6BQ
      • Novartis Investigative Site
  • Greater London
    • London, Greater London, United Kingdom, EN3 4GS
      • Novartis Investigative Site
  • Lancashire
    • Preston, Lancashire, United Kingdom, PR2 9QB
      • Novartis Investigative Site
  • Middlesex
    • Harrow, Middlesex, United Kingdom, HA1 3UJ
      • Novartis Investigative Site
  • North Manchester
    • Rochdale, North Manchester, United Kingdom, OL11 4AU
      • Novartis Investigative Site
  • Nothern Ireland
    • Portadown, Nothern Ireland, United Kingdom, BT63 5QQ
      • Novartis Investigative Site
  • Somerset
    • Taunton, Somerset, United Kingdom, TA1 5DA
      • Novartis Investigative Site
  • Stockton on Tees
    • Hardwick, Stockton on Tees, United Kingdom, TS19 8PE
      • Novartis Investigative Site
  • Surrey
    • Chertsey, Surrey, United Kingdom, KT16 0PZ
      • Novartis Investigative Site
  • Tyne and Wear
    • Newcastle upon Tyne, Tyne and Wear, United Kingdom, NE7 7DN
      • Novartis Investigative Site
    • Sunderland, Tyne and Wear, United Kingdom, SR4 7TP
      • Novartis Investigative Site
  • Wales
    • Cardiff, Wales, United Kingdom, CF5 4AD
      • Novartis Investigative Site
  • West Sussex
    • Chichester, West Sussex, United Kingdom, PO19 6SE
      • Novartis Investigative Site
• United States
  • Alabama
    • Andalusia, Alabama, United States, 36420
      • SEC Clinical Research LLC
    • Birmingham, Alabama, United States, 35243
      • Novartis Investigative Site
    • Birmingham, Alabama, United States, 35243
      • Grandview Med Group Research LLC
    • Huntsville, Alabama, United States, 35801
      • Novartis Investigative Site
    • Huntsville, Alabama, United States, 35801
      • Heart Center Research LLC
    • Mobile, Alabama, United States, 36608
      • Novartis Investigative Site
    • Mobile, Alabama, United States, 36608
      • Mobile Heart Specialists
  • Arizona
    • Cottonwood, Arizona, United States, 86326
      • Novartis Investigative Site
    • Gilbert, Arizona, United States, 85297
      • Mercy Gilbert Medical Center
    • Sun City West, Arizona, United States, 85375
      • Novartis Investigative Site
    • Sun City West, Arizona, United States, 85375
      • Clinical Research Inst of Arizona
    • Tucson, Arizona, United States, 85745
      • Novartis Investigative Site
    • Tucson, Arizona, United States, 85745
      • Eclipse Clinical Research
  • Arkansas
    • Little Rock, Arkansas, United States, 72204
      • Novartis Investigative Site
    • Little Rock, Arkansas, United States, 72204
      • Cardiology and Medicine Clinic PA
  • California
    • Beverly Hills, California, United States, 90211
      • Novartis Investigative Site
    • Beverly Hills, California, United States, 90211
      • National Heart Institute
    • Beverly Hills, California, United States, 90210
      • Cardiovascular Res Found
    • Covina, California, United States, 91723
      • Novartis Investigative Site
    • Covina, California, United States, 91723
      • Flourish Clinical Resrch Covin
    • Huntington Beach, California, United States, 92648
      • Novartis Investigative Site
    • Huntington Beach, California, United States, 92648
      • Diabetes Lipid Management Center
    • Irvine, California, United States, 92660
      • University of Calif Irvine Med Cntr
    • La Jolla, California, United States, 92037
      • Novartis Investigative Site
    • Long Beach, California, United States, 90806
      • Novartis Investigative Site
    • Long Beach, California, United States, 90806
      • Memorial Care Health System
    • Los Angeles, California, United States, 90033
      • Novartis Investigative Site
    • Los Angeles, California, United States, 90073
      • Novartis Investigative Site
    • Los Angeles, California, United States, 90033
      • Keck Medical Center USC
    • Northridge, California, United States, 91325
      • Novartis Investigative Site
    • Northridge, California, United States, 91325
      • Valley Clinical Trials
    • Orange, California, United States, 92868
      • Novartis Investigative Site
    • Palo Alto, California, United States, 94304
      • Stanford University Medical Center
    • San Diego, California, United States, 92103
      • University of California San Diego
    • San Francisco, California, United States, 94115
      • UCSF
    • San Francisco, California, United States, 94158
      • Novartis Investigative Site
    • Santa Ana, California, United States, 92704
      • Novartis Investigative Site
    • Santa Ana, California, United States, 92704
      • Helping Hands Medical Associates INC
    • Stanford, California, United States, 94305
      • Novartis Investigative Site
    • Stockton, California, United States, 95204
      • Novartis Investigative Site
    • Stockton, California, United States, 95204
      • Manshadi Heart Institute
    • West Hills, California, United States, 91307
      • Novartis Investigative Site
    • West Hills, California, United States, 91307
      • Interv Cardiology Med Grp
  • Colorado
    • Aurora, Colorado, United States, 80045
      • Novartis Investigative Site
    • Aurora, Colorado, United States, 80045
      • Univ Of Color Anschutz Med Center
  • Connecticut
    • Bridgeport, Connecticut, United States, 06610
      • Bridgeport Hospital
    • Bridgeport, Connecticut, United States, 06610
      • Novartis Investigative Site
    • Hartford, Connecticut, United States, 06102
      • Hartford Hospital
    • Hartford, Connecticut, United States, 06102-5037
      • Novartis Investigative Site
    • Waterbury, Connecticut, United States, 06708
      • Chase Medical Research LLC
    • Waterbury, Connecticut, United States, 06708
      • Novartis Investigative Site
  • Florida
    • Boca Raton, Florida, United States, 33434
      • Novartis Investigative Site
    • Boca Raton, Florida, United States, 33434
      • Excel Medical Clinical Trials LLC
    • Bradenton, Florida, United States, 34209
      • Cardiovascular and Vein Center of Florida
    • Bradenton, Florida, United States, 34209
      • Novartis Investigative Site
    • Brandon, Florida, United States, 33511
      • Novartis Investigative Site
    • Brandon, Florida, United States, 33511
      • Bay Area Cardiology Assoc
    • Fort Lauderdale, Florida, United States, 33312
      • Novartis Investigative Site
    • Hollywood, Florida, United States, 33021
      • CV Consultants of South Broward
    • Jacksonville, Florida, United States, 32205
      • Westside Center for Clinical Research
    • Jacksonville, Florida, United States, 32216
      • Jacksonville Center for Clinical Research
    • Jacksonville, Florida, United States, 32205
      • Novartis Investigative Site
    • Jacksonville, Florida, United States, 32216
      • Novartis Investigative Site
    • Jacksonville, Florida, United States, 32216
      • East Coast Institute For Research
    • Miami, Florida, United States, 33133
      • Infinite Clinical Research
    • Miami, Florida, United States, 33133
      • Novartis Investigative Site
    • Naples, Florida, United States, 34102
      • Novartis Investigative Site
    • Naples, Florida, United States, 34102
      • Southwest Florida Research
    • Naples, Florida, United States, 34102
      • Advanced Research for Health Improvement LLC
    • Port Charlotte, Florida, United States, 33952
      • Novartis Investigative Site
    • Port Charlotte, Florida, United States, 33952
      • Peace River Cardiovascular Center
    • Port Orange, Florida, United States, 32127
      • Progressive Medical Research
    • Port Orange, Florida, United States, 32127
      • Novartis Investigative Site
    • Saint Augustine, Florida, United States, 32086
      • Novartis Investigative Site
    • Saint Augustine, Florida, United States, 32086
      • East Coast Inst for Research LLC
    • Wellington, Florida, United States, 33449
      • Novartis Investigative Site
    • Wellington, Florida, United States, 33449
      • Cardiology Partners Clinical Research Institute
  • Georgia
    • Atlanta, Georgia, United States, 30322
      • Emory University
    • Atlanta, Georgia, United States, 30303
      • Grady Health System
    • Atlanta, Georgia, United States, 30309
      • Novartis Investigative Site
    • Atlanta, Georgia, United States, 30309
      • Piedmont Heart Institute
    • Atlanta, Georgia, United States, 30084
      • Novartis Investigative Site
    • Atlanta, Georgia, United States, 30324
      • Novartis Investigative Site
    • Dunwoody, Georgia, United States, 30338
      • Novartis Investigative Site
    • Peachtree Corners, Georgia, United States, 30092
      • Alta Pharmaceutical Research Center
    • Thomasville, Georgia, United States, 31792
      • Novartis Investigative Site
    • Thomasville, Georgia, United States, 31792
      • Cardiovascular Consultants of S GA
  • Illinois
    • Chicago, Illinois, United States, 60612
      • Rush University Medical Center
    • Park Ridge, Illinois, United States, 60068
      • Novartis Investigative Site
    • Park Ridge, Illinois, United States, 60068
      • Advocate Lutheran General Childrens Hospital
  • Indiana
    • Indianapolis, Indiana, United States, 46202 4800
      • Novartis Investigative Site
    • Indianapolis, Indiana, United States, 46202 4800
      • Krannert Institute of Cardiology
  • Iowa
    • Iowa City, Iowa, United States, 52242
      • Novartis Investigative Site
    • Iowa City, Iowa, United States, 52242
      • Uni Of Iowa Hospitals And Clinics
  • Kansas
    • Kansas City, Kansas, United States, 66160
      • Novartis Investigative Site
    • Kansas City, Kansas, United States, 66160
      • University of Kansas Hospital
    • Topeka, Kansas, United States, 66606
      • Novartis Investigative Site
    • Topeka, Kansas, United States, 66606
      • Cotton O Neil Clinical Res Center
  • Louisiana
    • Alexandria, Louisiana, United States, 71301
      • Novartis Investigative Site
    • Alexandria, Louisiana, United States, 71301
      • Christus Health Central Louisiana
    • Baton Rouge, Louisiana, United States, 70808
      • Novartis Investigative Site
    • Bogalusa, Louisiana, United States, 70427
      • Novartis Investigative Site
    • Bossier City, Louisiana, United States, 71111
      • Novartis Investigative Site
    • Covington, Louisiana, United States, 70433
      • Novartis Investigative Site
    • Covington, Louisiana, United States, 70433
      • Cardiovascular Associates Research
    • Covington, Louisiana, United States, 70433
      • Louisiana Heart Center Research
    • Eunice, Louisiana, United States, 70535
      • Novartis Investigative Site
    • Hammond, Louisiana, United States, 70403
      • Novartis Investigative Site
    • Hammond, Louisiana, United States, 70403
      • Heart Clinic of Hammond
    • Houma, Louisiana, United States, 70360
      • Novartis Investigative Site
    • Houma, Louisiana, United States, 70360
      • CV Institute of the South
    • Lafayette, Louisiana, United States, 70501
      • Horizon Research Grp
    • Metairie, Louisiana, United States, 70006
      • Novartis Investigative Site
    • Metairie, Louisiana, United States, 70006
      • Omega Clinical Research
    • New Orleans, Louisiana, United States, 70115
      • Novartis Investigative Site
    • New Orleans, Louisiana, United States, 70112
      • Tulane Uni Health Sciences Center
    • New Orleans, Louisiana, United States, 70115
      • Crescent City Physicians Inc
    • Opelousas, Louisiana, United States, 70570
      • Novartis Investigative Site
    • Opelousas, Louisiana, United States, 70570
      • CV Ins of the South
    • Shreveport, Louisiana, United States, 71105
      • Novartis Investigative Site
    • Shreveport, Louisiana, United States, 71105
      • Grace Research Llc
    • Slidell, Louisiana, United States, 70458
      • Novartis Investigative Site
    • Slidell, Louisiana, United States, 70458
      • Louisiana Heart Center Research
    • Zachary, Louisiana, United States, 70791
      • Southern Clinical Research
    • Zachary, Louisiana, United States, 70791
      • Novartis Investigative Site
  • Maine
    • Scarborough, Maine, United States, 04074
      • Novartis Investigative Site
    • Scarborough, Maine, United States, 04074
      • Maine Health Cardiology
  • Maryland
    • Baltimore, Maryland, United States, 21201
      • University of Maryland
    • Baltimore, Maryland, United States, 21201
      • Novartis Investigative Site
    • Baltimore, Maryland, United States, 21287
      • Novartis Investigative Site
    • Baltimore, Maryland, United States, 21209
      • Novartis Investigative Site
    • Baltimore, Maryland, United States, 21209
      • Sinai Ct for Throm Res and Drug Dev
    • Baltimore, Maryland, United States, 21287
      • Johns Hopkins Univ School of Med
    • Columbia, Maryland, United States, 21044
      • Johns Hopkins University
    • Columbia, Maryland, United States, 21044
      • Novartis Investigative Site
    • Ft. Washington, Maryland, United States, 20744
      • Anderson Medical Research
    • Ft. Washington, Maryland, United States, 20744
      • Novartis Investigative Site
    • Rockville, Maryland, United States, 20850
      • Novartis Investigative Site
    • Rockville, Maryland, United States, 20850
      • Adventist HealthCare Shady Grove Medical Center
  • Massachusetts
    • Boston, Massachusetts, United States, 02115
      • Novartis Investigative Site
    • Boston, Massachusetts, United States, 02114-2696
      • Novartis Investigative Site
    • Boston, Massachusetts, United States, 02115
      • Brigham and Womens Hosp Harvard Med School
    • Boston, Massachusetts, United States, 02114 2696
      • MGH
  • Michigan
    • Detroit, Michigan, United States, 48202
      • Henry Ford Hospital
    • Detroit, Michigan, United States, 48202
      • Novartis Investigative Site
    • Detroit, Michigan, United States, 48201
      • Wayne State University
    • Detroit, Michigan, United States, 48201
      • Novartis Investigative Site
    • Flint, Michigan, United States, 48504
      • Novartis Investigative Site
    • Flint, Michigan, United States, 48504
      • AA Medical Research Center
    • Grand Blanc, Michigan, United States, 48439
      • Genesys Regional Medical Center
    • Grand Blanc, Michigan, United States, 48439
      • Novartis Investigative Site
    • Kalamazoo, Michigan, United States, 49008
      • Novartis Investigative Site
    • Kalamazoo, Michigan, United States, 49008
      • Western Michigan University
    • Petoskey, Michigan, United States, 49770
      • Novartis Investigative Site
    • Petoskey, Michigan, United States, 49770
      • McLaren Ctr Research Innovation
    • Saginaw, Michigan, United States, 48601
      • Novartis Investigative Site
    • Saginaw, Michigan, United States, 48601
      • Central Michigan University
    • Wyoming, Michigan, United States, 49519
      • Novartis Investigative Site
    • Wyoming, Michigan, United States, 49519
      • Metro Health Univ of MI Health
  • Minnesota
    • Maplewood, Minnesota, United States, 55109
      • Saint Johns Hospital
    • Minneapolis, Minnesota, United States, 55455
      • University of Minnesota
    • Minneapolis, Minnesota, United States, 55455
      • Novartis Investigative Site
    • Minneapolis, Minnesota, United States, 55407
      • Minneapolis Heart Institute
    • Minneapolis, Minnesota, United States, 55407
      • Novartis Investigative Site
  • Mississippi
    • Belzoni, Mississippi, United States, 39038
      • Belzoni Clinical Research
    • Belzoni, Mississippi, United States, 39038
      • Novartis Investigative Site
    • Southaven, Mississippi, United States, 38671
      • Novartis Investigative Site
    • Southaven, Mississippi, United States, 38671
      • Stern Cardiovascular Foundation Inc
    • Yazoo City, Mississippi, United States, 39194
      • Novartis Investigative Site
  • Missouri
    • City of Saint Peters, Missouri, United States, 63303
      • StudyMetrix Research
    • City of Saint Peters, Missouri, United States, 63303
      • Novartis Investigative Site
    • St Louis, Missouri, United States, 63110
      • Novartis Investigative Site
    • St Louis, Missouri, United States, 63110
      • Washington Univ School Of Medicine
    • St Louis, Missouri, United States, 63128
      • Mercy South
    • St Louis, Missouri, United States, 63141
      • Mercy Hospital St Louis
  • Nebraska
    • Lincoln, Nebraska, United States, 68526
      • Novartis Investigative Site
    • Omaha, Nebraska, United States, 68114
      • Novartis Investigative Site
    • Omaha, Nebraska, United States, 68114
      • Quality Clinical Research
  • New Hampshire
    • Lebanon, New Hampshire, United States, 03756
      • Dartmouth Hitchcock Medical Center
    • Lebanon, New Hampshire, United States, 03756
      • Novartis Investigative Site
  • New Jersey
    • Ridgewood, New Jersey, United States, 07450
      • The Valley Hospital
    • Ridgewood, New Jersey, United States, 07450
      • Novartis Investigative Site
    • Summit, New Jersey, United States, 07901
      • Overlook Medical Center
    • Summit, New Jersey, United States, 07901
      • Novartis Investigative Site
  • New York
    • Albany, New York, United States, 12206
      • Albany Medical College
    • Manhasset, New York, United States, 11030
      • Novartis Investigative Site
    • Manhasset, New York, United States, 11030
      • Northwell Health
    • New York, New York, United States, 10016
      • Novartis Investigative Site
    • New York, New York, United States, 10029
      • Novartis Investigative Site
    • New York, New York, United States, 10021
      • Weill Cornell Medical Center
    • New York, New York, United States, 10021
      • Novartis Investigative Site
    • New York, New York, United States, 10075
      • Novartis Investigative Site
    • New York, New York, United States, 10029
      • Icahn School of Med at Mt Sinai
    • New York, New York, United States, 43210
      • Lenox Hill Hospital
    • New York, New York, United States, 10016
      • New York Uni Med Ctr
    • Riverhead, New York, United States, 11901
      • Northwell Health Physician Peconic
    • Rochester, New York, United States, 14642
      • Strong Memorial Hospital
    • Rochester, New York, United States, 14621
      • Rochester Regional Health
    • Southampton, New York, United States, 11968
      • Novartis Investigative Site
  • North Carolina
    • Charlotte, North Carolina, United States, 28204
      • Novartis Investigative Site
    • Charlotte, North Carolina, United States, 28204
      • Novant Health Heart Vas Inst
    • Greensboro, North Carolina, United States, 27405
      • Novartis Investigative Site
    • Greensboro, North Carolina, United States, 27405
      • Medication Management LLC
    • High Point, North Carolina, United States, 27262
      • Novartis Investigative Site
    • Raleigh, North Carolina, United States, 27609
      • Accellacare US Inc
    • Sanford, North Carolina, United States, 27330
      • Novartis Investigative Site
    • Shelby, North Carolina, United States, 28150
      • Novartis Investigative Site
    • Shelby, North Carolina, United States, 28150
      • Jones Family Practice PA
    • Winston-Salem, North Carolina, United States, 27157
      • Novartis Investigative Site
    • Winston-Salem, North Carolina, United States, 27157
      • Wake Forest University Baptist Medical Center
  • Ohio
    • Akron, Ohio, United States, 44304
      • Novartis Investigative Site
    • Akron, Ohio, United States, 44309
      • Akron Hospital Summa Health System
    • Canton, Ohio, United States, 44710
      • Novartis Investigative Site
    • Canton, Ohio, United States, 44710
      • Aultman Hospital
    • Cincinnati, Ohio, United States, 45267
      • University of Cincinnati
    • Cincinnati, Ohio, United States, 45267
      • Novartis Investigative Site
    • Cincinnati, Ohio, United States, 45219
      • Novartis Investigative Site
    • Cincinnati, Ohio, United States, 45246
      • Novartis Investigative Site
    • Cincinnati, Ohio, United States, 45246
      • Velocity Clin Research Springdale
    • Cincinnati, Ohio, United States, 45219
      • Lindner Ctr At The Christ Hosp
    • Cleveland, Ohio, United States, 44195
      • Cleveland Clinic Foundation
    • Cleveland, Ohio, United States, 44195
      • Novartis Investigative Site
    • Columbus, Ohio, United States, 43210
      • Ohio State University
    • Columbus, Ohio, United States, 43210
      • Novartis Investigative Site
    • Marion, Ohio, United States, 43302
      • Rama Research LLC
    • Marion, Ohio, United States, 43302
      • Novartis Investigative Site
  • Oregon
    • Portland, Oregon, United States, 97239
      • Novartis Investigative Site
    • Portland, Oregon, United States, 97239
      • Oregon Health Sciences University
  • Pennsylvania
    • Lancaster, Pennsylvania, United States, 17603
      • Novartis Investigative Site
    • Lancaster, Pennsylvania, United States, 17603
      • Lancaster General Health
    • Philadelphia, Pennsylvania, United States, 19104
      • Novartis Investigative Site
    • Philadelphia, Pennsylvania, United States, 19104
      • Perelman School of Medicine
    • Pittsburgh, Pennsylvania, United States, 15212
      • Allegheny General Hospital
    • Yardley, Pennsylvania, United States, 19067
      • Novartis Investigative Site
    • Yardley, Pennsylvania, United States, 19067
      • Cardiology Consultants of Philadelphia
  • Rhode Island
    • Providence, Rhode Island, United States, 02906
      • Miriam Hospital
    • Providence, Rhode Island, United States, 02906
      • Novartis Investigative Site
  • South Carolina
    • Fort Mill, South Carolina, United States, 29707
      • Novartis Investigative Site
    • Fort Mill, South Carolina, United States, 29707
      • Piedmont Research Partners LLC
    • Summerville, South Carolina, United States, 29485
      • Palmetto Clinical Research
    • Summerville, South Carolina, United States, 29485
      • Novartis Investigative Site
  • South Dakota
    • Rapid City, South Dakota, United States, 57701
      • Novartis Investigative Site
    • Rapid City, South Dakota, United States, 57701
      • Monument Health Clinical Research
  • Tennessee
    • Germantown, Tennessee, United States, 38138
      • Novartis Investigative Site
    • Germantown, Tennessee, United States, 38138
      • The Stern Cardiovascular Foundation
    • Jackson, Tennessee, United States, 38301
      • Novartis Investigative Site
    • Jackson, Tennessee, United States, 38301
      • Apex Cardiology Research Associates of Jackson
    • Nashville, Tennessee, United States, 37232
      • Novartis Investigative Site
    • Nashville, Tennessee, United States, 37232
      • Vanderbilt Univ Medi Cen
    • Powell, Tennessee, United States, 37849
      • Novartis Investigative Site
    • Powell, Tennessee, United States, 37849
      • Cardiovascular Res of Knoxville LLC
  • Texas
    • Dallas, Texas, United States, 75390
      • UT Southwestern Medical Center
    • Dallas, Texas, United States, 75235
      • Novartis Investigative Site
    • Dallas, Texas, United States, 75226
      • Novartis Investigative Site
    • Dallas, Texas, United States, 75231
      • Novartis Investigative Site
    • Dallas, Texas, United States, 75231
      • North Texas Endocrine Center
    • Dallas, Texas, United States, 75226
      • Soltero Cardiovascular Research Center
    • Dallas, Texas, United States, 75235
      • SW Family Medicine Associates
    • Houston, Texas, United States, 77030
      • Baylor College of Medicine
    • Houston, Texas, United States, 77030
      • Novartis Investigative Site
    • Livingston, Texas, United States, 77351
      • Novartis Investigative Site
    • Marshall, Texas, United States, 75670
      • Grace Research
    • Temple, Texas, United States, 76508
      • Novartis Investigative Site
    • Tomball, Texas, United States, 77375
      • Novartis Investigative Site
    • Tomball, Texas, United States, 77375
      • Northwest Houston Clinical Research PLLC
  • Utah
    • Bountiful, Utah, United States, 84010
      • Progressive Clinical Research
    • Bountiful, Utah, United States, 84010
      • Novartis Investigative Site
    • Murray, Utah, United States, 84107
      • Intermountain Medical Center
    • Murray, Utah, United States, 84107
      • Novartis Investigative Site
    • Salt Lake City, Utah, United States, 84132-0001
      • The University of Utah
  • Virginia
    • Danville, Virginia, United States, 24541
      • Novartis Investigative Site
    • Falls Church, Virginia, United States, 22042
      • Inova Fairfax Hospital
    • Falls Church, Virginia, United States, 22042
      • Virginia Heart
    • Falls Church, Virginia, United States, 22042
      • Novartis Investigative Site
    • Manassas, Virginia, United States, 20109
      • Novartis Investigative Site
    • Manassas, Virginia, United States, 20109
      • Carient Heart and Vascular
    • Norfolk, Virginia, United States, 23504
      • York Clinical Research
    • Norfolk, Virginia, United States, 23510
      • Novartis Investigative Site
    • Richmond, Virginia, United States, 23219
      • Dominion Medical Associates
    • Richmond, Virginia, United States, 23219
      • Novartis Investigative Site
  • Washington
    • Seattle, Washington, United States, 98104
      • Harborview Medical Center
    • Seattle, Washington, United States, 98104
      • Novartis Investigative Site
    • Seattle, Washington, United States, 98122
      • Novartis Investigative Site
    • Seattle, Washington, United States, 98195
      • Novartis Investigative Site
    • Seattle, Washington, United States, 98122
      • Swedish Medical Center-Cardiovascular Research
    • Seattle, Washington, United States, 98195
      • Univ of Washington Medical Center
  • West Virginia
    • Morgantown, West Virginia, United States, 26506
      • West Virginia University Hospital
  • Wisconsin
    • Milwaukee, Wisconsin, United States, 53215
      • Novartis Investigative Site
    • Milwaukee, Wisconsin, United States, 53215
      • St Luke s Medical Center Aurora

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 80 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No

Description

Key Inclusion Criteria

• Lp(a) ≥ 70 mg/dL at the screening visit, measured at the Central laboratory
• Myocardial infarction: ≥ 3 months from screening and randomization to ≤ 10 years prior to the screening visit
• Ischemic stroke: ≥ 3 months from screening and randomization to ≤ 10 years prior to the screening visit
• Clinically significant symptomatic peripheral artery disease

Key Exclusion Criteria

• Uncontrolled hypertension
• Heart failure New York Heart Association (NYHA) class IV
• History of malignancy of any organ system
• History of hemorrhagic stroke or other major bleeding
• Platelet count ≤LLN
• Active liver disease or hepatic dysfunction
• Significant kidney disease
• Pregnant or nursing women

Other protocol-defined inclusion/exclusion criteria may apply at the end.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: TQJ230; TQJ230 80 mg injected monthly administered subcutaneously	Drug: TQJ230; TQJ230 80 mg injected monthly administered subcutaneously
Placebo Comparator: Placebo; Monthly subcutaneous injections.	Drug: Placebo; Placebo to match TQJ230 prefilled syringe to be injected subcutaneously; Other Names: Placebo to match TQJ230

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Time to first occurrence of clinical endpoint committee confirmed expanded major adverse cardiovascular events in patients with elevated Lp(a) ≥ 70 mg/dL	Demonstrate the superiority of pelacarsen (TQJ230) compared to placebo in reducing the risk of expanded MACE (cardiovascular death, non-fatal MI, non-fatal stroke and urgent coronary re-vascularization requiring hospitalization) in the overall study population with established CVD and (Lp(a) ≥ 70 mg/dL)	approximately 4 years
Time to the first occurrence of clinical endpoint committee confirmed expanded major adverse cardiovascular events in a population of patients with elevated Lp(a) ≥ 90 mg/dL.	Demonstrate the superiority of pelacarsen (TQJ230) compared to placebo in reducing the risk of expanded MACE (cardiovascular death, non-fatal MI, non-fatal stroke and urgent coronary re-vascularization requiring hospitalization) in the overall study population with established CVD and (Lp(a) ≥ 90 mg/dL)	approximately 4 years

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Time to the first occurrence of the clinical endpoint committee confirmed composite endpoint of major adverse cardiovascular events (CV death, non-fatal MI, and non-fatal stroke)	Demonstrate the superiority of pelacarsen (TQJ230) compared to placebo in reducing the risk of the MACE composite of CV death, nonfatal MI and non-fatal stroke.	approximately 4 years
Time to the first occurrence of the clinical endpoint committee confirmed composite endpoint of coronary heart disease: coronary heart disease death, non-fatal MI, urgent coronary re-vascularization requiring hospitalization	Demonstrate the superiority of pelacarsen (TQJ230) compared to placebo in reducing the risk of the composite of coronary heart disease (CHD) outcomes: death due to CHD, nonfatal MI and urgent coronary revascularization requiring hospitalization.	approximately 4 years
Time to Clinical endpoint Committee confirmed all-cause death	Evaluation by clinical endpoint committee the rate of all-cause death	approximately 4 years
Change in Lp(a) in the log scale from baseline	Demonstrate the superiority of pelacarsen (TQJ230) compared to placebo in lowering the Lp(a) level at 1 year	Baseline, year 1

Collaborators and Investigators

• Sponsor: Novartis Pharmaceuticals
• Investigators: Study Director: Novartis Pharmaceuticals, Novartis Pharmaceuticals

Publications and helpful links

General Publications

• Tsimikas S, Reeves RR, Patel MP. Always Present, But Now Rediscovered: Lp(a) as a Predictor of Long-Term Outcomes in PCI. JACC Cardiovasc Interv. 2021 Sep 27;14(18):2069-2072. doi: 10.1016/j.jcin.2021.08.032. No abstract available.
• Plakogiannis R, Sorbera M, Fischetti B, Chen M. The Role of Antisense Therapies Targeting Lipoprotein(a). J Cardiovasc Pharmacol. 2021 Jul 1;78(1):e5-e11. doi: 10.1097/FJC.0000000000001045.
• Nicholls SJ, Nelson AJ, Michael LF. Oral agents for lowering lipoprotein(a). Curr Opin Lipidol. 2024 Dec 1;35(6):275-280. doi: 10.1097/MOL.0000000000000953. Epub 2024 Sep 25.
• Dimitriadis K, Theofilis P, Iliakis P, Pyrpyris N, Dri E, Sakalidis A, Soulaidopoulos S, Tsioufis P, Fragkoulis C, Chrysohoou C, Tsiachris D, Tsioufis K. Management of dyslipidemia in coronary artery disease: the present and the future. Coron Artery Dis. 2024 Sep 1;35(6):516-524. doi: 10.1097/MCA.0000000000001375. Epub 2024 Apr 29.
• Karp A, Jacobs M, Barris B, Labkowsky A, Frishman WH. Lipoprotein(a): A Review of Risk Factors, Measurements, and Novel Treatment Modalities. Cardiol Rev. 2025 Jul-Aug 01;33(4):352-358. doi: 10.1097/CRD.0000000000000667. Epub 2024 Feb 28.
• Cho L, Nicholls SJ, Nordestgaard BG, Landmesser U, Tsimikas S, Blaha MJ, Leitersdorf E, Lincoff AM, Lesogor A, Manning B, Kozlovski P, Cao H, Wang J, Nissen SE. Design and Rationale of Lp(a)HORIZON Trial: Assessing the Effect of Lipoprotein(a) Lowering With Pelacarsen on Major Cardiovascular Events in Patients With CVD and Elevated Lp(a). Am Heart J. 2025 Sep;287:1-9. doi: 10.1016/j.ahj.2025.03.019. Epub 2025 Apr 2.
• Burvill A, Watts GF, Norman R, Ademi Z. Early health technology assessment of gene silencing therapies for lowering lipoprotein(a) in the secondary prevention of coronary heart disease. J Clin Lipidol. 2024 Nov-Dec;18(6):e946-e956. doi: 10.1016/j.jacl.2024.08.012. Epub 2024 Aug 31.
• Byambaa E, Roshanravan B, Berglund L. Lipoprotein(a) and CKD: Insights into New Therapeutic Opportunities. Clin J Am Soc Nephrol. 2025 Dec 2. doi: 10.2215/CJN.0000000968. Online ahead of print.

Study record dates

Study Major Dates

• Study Start (Actual): December 12, 2019
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): June 30, 2026

Study Registration Dates

• First Submitted: July 16, 2019
• First Submitted That Met QC Criteria: July 16, 2019
• First Posted (Actual): July 17, 2019

Study Record Updates

• Last Update Posted (Actual): May 6, 2026
• Last Update Submitted That Met QC Criteria: May 4, 2026
• Last Verified: May 1, 2026

More Information

Terms related to this study

• Keywords: Pelacarsen; Stroke,; Lipoprotein(a),; Lp(a),; CVD,; myocardial infarction,; PAD,
• Additional Relevant MeSH Terms: Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Pathologic Processes; Heart Diseases; Infarction; Necrosis; Myocardial Ischemia; Ischemia; Pathological Conditions, Signs and Symptoms; Stroke; Cardiovascular Diseases; Myocardial Infarction
• Other Study ID Numbers: CTQJ230A12301 (Other Identifier: Novartis); 2019-001076-11 (EudraCT Number)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES

IPD Plan Description

Novartis is committed to sharing with qualified external researchers, access to patient -level data and supporting clinical documents from eligible studies. These requests are reviewed and approved by an independent review panel on the basis of scientific merit. All data provided is anonymized to respect the privacy of patients who have participated in the trial in line with the applicable laws and regulations.

This trial data availability is according to the criteria and process described on www.clinicalstudydatarequest.com.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: Yes
• Studies a U.S. FDA-regulated device product: No