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Vurdering af virkningen af Lipoprotein (a) Sænkning med Pelacarsen (TQJ230) på større kardiovaskulære hændelser hos patienter med CVD (Lp(a)HORIZON)

4. maj 2026 opdateret af: Novartis Pharmaceuticals

Et randomiseret dobbeltblindt, placebokontrolleret, multicenterforsøg, der vurderer virkningen af lipoprotein (a) sænkning med Pelacarsen (TQJ230) på større kardiovaskulære hændelser hos patienter med etableret kardiovaskulær sygdom

Dette er et pivotal fase 3-studie designet til at understøtte en indikation for reduktion af kardiovaskulær risiko hos patienter med etableret CVD og forhøjet Lp(a)

Studieoversigt

Status

Aktiv, ikke rekrutterende

Betingelser

Hjerte-kar-sygdomme og lipoprotein(a)

Intervention / Behandling

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

8323

Fase

Fase 3

Udvidet adgang

Ledig uden for det kliniske forsøg. Se udvidet adgangsregistrering.

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Argentina
- - Caba, Argentina, C1426
    - Novartis Investigative Site
  - Capital Federal, Argentina, C1023AAB
    - Novartis Investigative Site
  - Corrientes, Argentina, W3400CDS
    - Novartis Investigative Site
  - Córdoba, Argentina, X5002
    - Novartis Investigative Site
  - San Luis, Argentina, D5702JRS
    - Novartis Investigative Site
- Buenos Aires
  - CABA, Buenos Aires, Argentina, 1407
    - Novartis Investigative Site
  - CABA, Buenos Aires, Argentina, C1056ABI
    - Novartis Investigative Site
  - CABA, Buenos Aires, Argentina, 1280
    - Novartis Investigative Site
  - CABA, Buenos Aires, Argentina, 1426
    - Novartis Investigative Site
  - Mar del Plata, Buenos Aires, Argentina, 7600
    - Novartis Investigative Site
  - Ramos Mejía, Buenos Aires, Argentina, B1704ETD
    - Novartis Investigative Site
- Córdoba Province
  - Córdoba, Córdoba Province, Argentina, 5000
    - Novartis Investigative Site
- San Miguel de Tucuman
  - San Miguel de Tucumán, San Miguel de Tucuman, Argentina, T4000ICL
    - Novartis Investigative Site
- Santa Fe Province
  - Rosario, Santa Fe Province, Argentina, 2000
    - Novartis Investigative Site
  - Rosario, Santa Fe Province, Argentina, S200CVD
    - Novartis Investigative Site
  - Santa Fe, Santa Fe Province, Argentina, S3000FWO
    - Novartis Investigative Site
- Tucumán Province
  - San Miguel Tucuman, Tucumán Province, Argentina, T4000IFL
    - Novartis Investigative Site
Australien
- - Liverpool, Australien, 2170
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- New South Wales
  - Camperdown, New South Wales, Australien, 2050
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- Queensland
  - Chemside, Queensland, Australien, 4032
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  - Southport, Queensland, Australien, 4215
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  - Woolloongabba, Queensland, Australien, 4102
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- Victoria
  - Clayton, Victoria, Australien, 3168
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- Western Australia
  - Perth, Western Australia, Australien, 6000
    - Novartis Investigative Site
Belgien
- - Bruges, Belgien, 8000
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  - Dendermonde, Belgien, 9200
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  - Huy, Belgien, 4500
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  - Mechelen, Belgien, 2800
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- Brussels Capital
  - Brussels, Brussels Capital, Belgien, 1070
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- Limburg
  - Genk, Limburg, Belgien, 3600
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- Oost Vlaanderen
  - Aalst, Oost Vlaanderen, Belgien, 9300
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- West-Vlaanderen
  - Kortrijk, West-Vlaanderen, Belgien, 8500
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Brasilien
- - Rio de Janeiro, Brasilien, 20241-180
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- Alagoas
  - Maceió, Alagoas, Brasilien, 57051-160
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- Espírito Santo
  - Vitória, Espírito Santo, Brasilien, 29055-450
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- Estado de Bahia
  - Salvador, Estado de Bahia, Brasilien, 40170-130
    - Novartis Investigative Site
- Federal District
  - Brasília, Federal District, Brasilien, 70390-700
    - Novartis Investigative Site
- Goiás
  - Goiânia, Goiás, Brasilien, 74605-020
    - Novartis Investigative Site
- Minas Gerais
  - Belo Horizonte, Minas Gerais, Brasilien, 30150-270
    - Novartis Investigative Site
  - Belo Horizonte, Minas Gerais, Brasilien, 30220-330
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  - Juiz de Fora, Minas Gerais, Brasilien, 36033-318
    - Novartis Investigative Site
  - Uberlândia, Minas Gerais, Brasilien, 38400 500
    - Novartis Investigative Site
- Paraná
  - Curitiba, Paraná, Brasilien, 80730-150
    - Novartis Investigative Site
  - Curitiba, Paraná, Brasilien, 80230-130
    - Novartis Investigative Site
- Rio Grande do Sul
  - Canoas, Rio Grande do Sul, Brasilien, 92425 900
    - Novartis Investigative Site
  - Porto Alegre, Rio Grande do Sul, Brasilien, 90880-480
    - Novartis Investigative Site
  - Porto Alegre, Rio Grande do Sul, Brasilien, 90160-093
    - Novartis Investigative Site
- Santa Catarina
  - Blumenau, Santa Catarina, Brasilien, 89020-430
    - Novartis Investigative Site
- Sergipe
  - Aracaju, Sergipe, Brasilien, 49055-530
    - Novartis Investigative Site
- São Paulo
  - Campinas, São Paulo, Brasilien, 13060 080
    - Novartis Investigative Site
  - Campinas, São Paulo, Brasilien, 13092133
    - Novartis Investigative Site
  - Ribeirão Preto, São Paulo, Brasilien, 14026-020
    - Novartis Investigative Site
  - Santo André, São Paulo, Brasilien, 09060-870
    - Novartis Investigative Site
  - Santo André, São Paulo, Brasilien, 09090-790
    - Novartis Investigative Site
  - Sao Jose Rio Preto, São Paulo, Brasilien, 15090 000
    - Novartis Investigative Site
  - Sao Jose Rio Preto, São Paulo, Brasilien, 15015-750
    - Novartis Investigative Site
  - São Paulo, São Paulo, Brasilien, 04005-003
    - Novartis Investigative Site
  - São Paulo, São Paulo, Brasilien, 04266 010
    - Novartis Investigative Site
  - São Paulo, São Paulo, Brasilien, 05403 000
    - Novartis Investigative Site
  - São Paulo, São Paulo, Brasilien, 01323 000
    - Novartis Investigative Site
  - São Paulo, São Paulo, Brasilien, 04023-900
    - Novartis Investigative Site
  - São Paulo, São Paulo, Brasilien, 05403-900
    - Novartis Investigative Site
Bulgarien
- - Burgas, Bulgarien, 8001
    - Novartis Investigative Site
  - Pernik, Bulgarien, 2300
    - Novartis Investigative Site
  - Pleven, Bulgarien, 5800
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  - Plovdiv, Bulgarien, 4000
    - Novartis Investigative Site
  - Rousse, Bulgarien, 7002
    - Novartis Investigative Site
  - Sofia, Bulgarien, 1233
    - Novartis Investigative Site
  - Sofia, Bulgarien, 1750
    - Novartis Investigative Site
- Bulgaria
  - Blagoevgrad, Bulgaria, Bulgarien, 2700
    - Novartis Investigative Site
Canada
- British Columbia
  - Vancouver, British Columbia, Canada, V6Z 1Y6
    - Novartis Investigative Site
  - Vancouver, British Columbia, Canada, V5Z 1M9
    - Novartis Investigative Site
  - Victoria, British Columbia, Canada, V8R4R2
    - Novartis Investigative Site
  - Victoria, British Columbia, Canada, V8T 5G4
    - Novartis Investigative Site
- Ontario
  - Oakville, Ontario, Canada, L6K 3W7
    - Novartis Investigative Site
  - Toronto, Ontario, Canada, M9V 4B4
    - Novartis Investigative Site
- Quebec
  - Lévis, Quebec, Canada, G6V 4Z5
    - Novartis Investigative Site
  - Montreal, Quebec, Canada, H4A 3J1
    - Novartis Investigative Site
  - Montreal, Quebec, Canada, H3T 1E2
    - Novartis Investigative Site
  - Montreal, Quebec, Canada, H1T 1C8
    - Novartis Investigative Site
  - Montreal, Quebec, Canada, H2X 1R9
    - Novartis Investigative Site
  - Québec, Quebec, Canada, G1R 2J6
    - Novartis Investigative Site
  - Québec, Quebec, Canada, G1V 4W2
    - Novartis Investigative Site
  - Québec, Quebec, Canada, G1V 4G2
    - Novartis Investigative Site
  - Québec, Quebec, Canada, G1V 4G5
    - Novartis Investigative Site
  - Terrebonne, Quebec, Canada, J6V 2H2
    - Novartis Investigative Site
Chile
- - Santiago, Chile, 7500710
    - Novartis Investigative Site
  - Santiago, Chile, 8380456
    - Novartis Investigative Site
- RM
  - Santiago, RM, Chile, 7500588
    - Novartis Investigative Site
- Santiago Metropolitan
  - Santiago, Santiago Metropolitan, Chile, 8331143
    - Novartis Investigative Site
  - Santiago, Santiago Metropolitan, Chile, 7500710
    - Novartis Investigative Site
  - Santiago, Santiago Metropolitan, Chile, 8380465
    - Novartis Investigative Site
Colombia
- - Bogotá, Colombia, 111211
    - Novartis Investigative Site
  - Medellín, Colombia, 050037
    - Novartis Investigative Site
  - San Gil, Colombia, 684031
    - Novartis Investigative Site
- Antioquia
  - Medellín, Antioquia, Colombia, 050001
    - Novartis Investigative Site
- Colombia
  - Barranquilla, Colombia, Colombia, 080020
    - Novartis Investigative Site
- Santander Department
  - Bucaramanga, Santander Department, Colombia, 681017
    - Novartis Investigative Site
- Valle del Cauca Department
  - Cali, Valle del Cauca Department, Colombia, 760001
    - Novartis Investigative Site
  - Cali, Valle del Cauca Department, Colombia, 760032
    - Novartis Investigative Site
Danmark
- - Aarhus N, Danmark, 8200
    - Novartis Investigative Site
  - Copenhagen, Danmark, DK-2100
    - Novartis Investigative Site
  - Esbjerg, Danmark, 6700
    - Novartis Investigative Site
  - Gistrup, Danmark, 9260
    - Novartis Investigative Site
  - Herlev, Danmark, DK-2730
    - Novartis Investigative Site
  - Roskilde, Danmark, 4000
    - Novartis Investigative Site
  - Viborg, Danmark, 8800
    - Novartis Investigative Site
Det Forenede Kongerige
- - Birmingham, Det Forenede Kongerige, B9 5SS
    - Novartis Investigative Site
  - Bournemouth, Det Forenede Kongerige, BH7 7DW
    - Novartis Investigative Site
  - Bristol, Det Forenede Kongerige, BS2 8HW
    - Novartis Investigative Site
  - Bromwich, Det Forenede Kongerige, B71 4HJ
    - Novartis Investigative Site
  - Cardiff, Det Forenede Kongerige, CF64 2XX
    - Novartis Investigative Site
  - Chesterfield, Det Forenede Kongerige, S40 4AA
    - Novartis Investigative Site
  - Dundee, Det Forenede Kongerige, DD1 9SY
    - Novartis Investigative Site
  - Edinburgh, Det Forenede Kongerige, EH16 4SA
    - Novartis Investigative Site
  - Glasgow, Det Forenede Kongerige, G20 7BE
    - Novartis Investigative Site
  - Leicester, Det Forenede Kongerige, LE3 9QP
    - Novartis Investigative Site
  - Liverpool, Det Forenede Kongerige, L7 8XP
    - Novartis Investigative Site
  - London, Det Forenede Kongerige, W12 0HS
    - Novartis Investigative Site
  - Londonderry, Det Forenede Kongerige, BT47 6SB
    - Novartis Investigative Site
  - Manchester, Det Forenede Kongerige, M13 9WL
    - Novartis Investigative Site
  - Middlesbrough, Det Forenede Kongerige, TS4 3BW
    - Novartis Investigative Site
  - Middlesex, Det Forenede Kongerige, UB9 6JH
    - Novartis Investigative Site
  - Newport, Det Forenede Kongerige, NP20 2UB
    - Novartis Investigative Site
  - Norwich, Det Forenede Kongerige, NR4 7UY
    - Novartis Investigative Site
  - Plymouth, Det Forenede Kongerige, PL6 8DH
    - Novartis Investigative Site
  - Rhyl, Det Forenede Kongerige, LL18 5UJ
    - Novartis Investigative Site
  - Sheffield, Det Forenede Kongerige, S5 7AU
    - Novartis Investigative Site
  - Swansea, Det Forenede Kongerige, SA2 8QA
    - Novartis Investigative Site
  - Tyne and Wear, Det Forenede Kongerige, NE29 8NH
    - Novartis Investigative Site
  - Wiltshire, Det Forenede Kongerige, SN15 2SB
    - Novartis Investigative Site
  - Wrexham, Det Forenede Kongerige, LL13 7TD
    - Novartis Investigative Site
- Dorset
  - Dorchester, Dorset, Det Forenede Kongerige, DT1 2JY
    - Novartis Investigative Site
- GBR
  - London, GBR, Det Forenede Kongerige, EC1M 6BQ
    - Novartis Investigative Site
- Greater London
  - London, Greater London, Det Forenede Kongerige, EN3 4GS
    - Novartis Investigative Site
- Lancashire
  - Preston, Lancashire, Det Forenede Kongerige, PR2 9QB
    - Novartis Investigative Site
- Middlesex
  - Harrow, Middlesex, Det Forenede Kongerige, HA1 3UJ
    - Novartis Investigative Site
- North Manchester
  - Rochdale, North Manchester, Det Forenede Kongerige, OL11 4AU
    - Novartis Investigative Site
- Nothern Ireland
  - Portadown, Nothern Ireland, Det Forenede Kongerige, BT63 5QQ
    - Novartis Investigative Site
- Somerset
  - Taunton, Somerset, Det Forenede Kongerige, TA1 5DA
    - Novartis Investigative Site
- Stockton on Tees
  - Hardwick, Stockton on Tees, Det Forenede Kongerige, TS19 8PE
    - Novartis Investigative Site
- Surrey
  - Chertsey, Surrey, Det Forenede Kongerige, KT16 0PZ
    - Novartis Investigative Site
- Tyne and Wear
  - Newcastle upon Tyne, Tyne and Wear, Det Forenede Kongerige, NE7 7DN
    - Novartis Investigative Site
  - Sunderland, Tyne and Wear, Det Forenede Kongerige, SR4 7TP
    - Novartis Investigative Site
- Wales
  - Cardiff, Wales, Det Forenede Kongerige, CF5 4AD
    - Novartis Investigative Site
- West Sussex
  - Chichester, West Sussex, Det Forenede Kongerige, PO19 6SE
    - Novartis Investigative Site
Forenede Stater
- Alabama
  - Andalusia, Alabama, Forenede Stater, 36420
    - SEC Clinical Research LLC
  - Birmingham, Alabama, Forenede Stater, 35243
    - Novartis Investigative Site
  - Birmingham, Alabama, Forenede Stater, 35243
    - Grandview Med Group Research LLC
  - Huntsville, Alabama, Forenede Stater, 35801
    - Novartis Investigative Site
  - Huntsville, Alabama, Forenede Stater, 35801
    - Heart Center Research LLC
  - Mobile, Alabama, Forenede Stater, 36608
    - Novartis Investigative Site
  - Mobile, Alabama, Forenede Stater, 36608
    - Mobile Heart Specialists
- Arizona
  - Cottonwood, Arizona, Forenede Stater, 86326
    - Novartis Investigative Site
  - Gilbert, Arizona, Forenede Stater, 85297
    - Mercy Gilbert Medical Center
  - Sun City West, Arizona, Forenede Stater, 85375
    - Novartis Investigative Site
  - Sun City West, Arizona, Forenede Stater, 85375
    - Clinical Research Inst of Arizona
  - Tucson, Arizona, Forenede Stater, 85745
    - Novartis Investigative Site
  - Tucson, Arizona, Forenede Stater, 85745
    - Eclipse Clinical Research
- Arkansas
  - Little Rock, Arkansas, Forenede Stater, 72204
    - Novartis Investigative Site
  - Little Rock, Arkansas, Forenede Stater, 72204
    - Cardiology and Medicine Clinic PA
- California
  - Beverly Hills, California, Forenede Stater, 90211
    - Novartis Investigative Site
  - Beverly Hills, California, Forenede Stater, 90211
    - National Heart Institute
  - Beverly Hills, California, Forenede Stater, 90210
    - Cardiovascular Res Found
  - Covina, California, Forenede Stater, 91723
    - Novartis Investigative Site
  - Covina, California, Forenede Stater, 91723
    - Flourish Clinical Resrch Covin
  - Huntington Beach, California, Forenede Stater, 92648
    - Novartis Investigative Site
  - Huntington Beach, California, Forenede Stater, 92648
    - Diabetes Lipid Management Center
  - Irvine, California, Forenede Stater, 92660
    - University of Calif Irvine Med Cntr
  - La Jolla, California, Forenede Stater, 92037
    - Novartis Investigative Site
  - Long Beach, California, Forenede Stater, 90806
    - Novartis Investigative Site
  - Long Beach, California, Forenede Stater, 90806
    - Memorial Care Health System
  - Los Angeles, California, Forenede Stater, 90033
    - Novartis Investigative Site
  - Los Angeles, California, Forenede Stater, 90073
    - Novartis Investigative Site
  - Los Angeles, California, Forenede Stater, 90033
    - Keck Medical Center USC
  - Northridge, California, Forenede Stater, 91325
    - Novartis Investigative Site
  - Northridge, California, Forenede Stater, 91325
    - Valley Clinical Trials
  - Orange, California, Forenede Stater, 92868
    - Novartis Investigative Site
  - Palo Alto, California, Forenede Stater, 94304
    - Stanford University Medical Center
  - San Diego, California, Forenede Stater, 92103
    - University of California San Diego
  - San Francisco, California, Forenede Stater, 94115
    - UCSF
  - San Francisco, California, Forenede Stater, 94158
    - Novartis Investigative Site
  - Santa Ana, California, Forenede Stater, 92704
    - Novartis Investigative Site
  - Santa Ana, California, Forenede Stater, 92704
    - Helping Hands Medical Associates INC
  - Stanford, California, Forenede Stater, 94305
    - Novartis Investigative Site
  - Stockton, California, Forenede Stater, 95204
    - Novartis Investigative Site
  - Stockton, California, Forenede Stater, 95204
    - Manshadi Heart Institute
  - West Hills, California, Forenede Stater, 91307
    - Novartis Investigative Site
  - West Hills, California, Forenede Stater, 91307
    - Interv Cardiology Med Grp
- Colorado
  - Aurora, Colorado, Forenede Stater, 80045
    - Novartis Investigative Site
  - Aurora, Colorado, Forenede Stater, 80045
    - Univ Of Color Anschutz Med Center
- Connecticut
  - Bridgeport, Connecticut, Forenede Stater, 06610
    - Bridgeport Hospital
  - Bridgeport, Connecticut, Forenede Stater, 06610
    - Novartis Investigative Site
  - Hartford, Connecticut, Forenede Stater, 06102
    - Hartford Hospital
  - Hartford, Connecticut, Forenede Stater, 06102-5037
    - Novartis Investigative Site
  - Waterbury, Connecticut, Forenede Stater, 06708
    - Chase Medical Research LLC
  - Waterbury, Connecticut, Forenede Stater, 06708
    - Novartis Investigative Site
- Florida
  - Boca Raton, Florida, Forenede Stater, 33434
    - Novartis Investigative Site
  - Boca Raton, Florida, Forenede Stater, 33434
    - Excel Medical Clinical Trials LLC
  - Bradenton, Florida, Forenede Stater, 34209
    - Cardiovascular and Vein Center of Florida
  - Bradenton, Florida, Forenede Stater, 34209
    - Novartis Investigative Site
  - Brandon, Florida, Forenede Stater, 33511
    - Novartis Investigative Site
  - Brandon, Florida, Forenede Stater, 33511
    - Bay Area Cardiology Assoc
  - Fort Lauderdale, Florida, Forenede Stater, 33312
    - Novartis Investigative Site
  - Hollywood, Florida, Forenede Stater, 33021
    - CV Consultants of South Broward
  - Jacksonville, Florida, Forenede Stater, 32205
    - Westside Center For Clinical Research
  - Jacksonville, Florida, Forenede Stater, 32216
    - Jacksonville Center for Clinical Research
  - Jacksonville, Florida, Forenede Stater, 32205
    - Novartis Investigative Site
  - Jacksonville, Florida, Forenede Stater, 32216
    - Novartis Investigative Site
  - Jacksonville, Florida, Forenede Stater, 32216
    - East Coast Institute for Research
  - Miami, Florida, Forenede Stater, 33133
    - Infinite Clinical Research
  - Miami, Florida, Forenede Stater, 33133
    - Novartis Investigative Site
  - Naples, Florida, Forenede Stater, 34102
    - Novartis Investigative Site
  - Naples, Florida, Forenede Stater, 34102
    - Southwest Florida Research
  - Naples, Florida, Forenede Stater, 34102
    - Advanced Research for Health Improvement LLC
  - Port Charlotte, Florida, Forenede Stater, 33952
    - Novartis Investigative Site
  - Port Charlotte, Florida, Forenede Stater, 33952
    - Peace River Cardiovascular Center
  - Port Orange, Florida, Forenede Stater, 32127
    - Progressive Medical Research
  - Port Orange, Florida, Forenede Stater, 32127
    - Novartis Investigative Site
  - Saint Augustine, Florida, Forenede Stater, 32086
    - Novartis Investigative Site
  - Saint Augustine, Florida, Forenede Stater, 32086
    - East Coast Inst for Research LLC
  - Wellington, Florida, Forenede Stater, 33449
    - Novartis Investigative Site
  - Wellington, Florida, Forenede Stater, 33449
    - Cardiology Partners Clinical Research Institute
- Georgia
  - Atlanta, Georgia, Forenede Stater, 30322
    - Emory University
  - Atlanta, Georgia, Forenede Stater, 30303
    - Grady Health System
  - Atlanta, Georgia, Forenede Stater, 30309
    - Novartis Investigative Site
  - Atlanta, Georgia, Forenede Stater, 30309
    - Piedmont Heart Institute
  - Atlanta, Georgia, Forenede Stater, 30084
    - Novartis Investigative Site
  - Atlanta, Georgia, Forenede Stater, 30324
    - Novartis Investigative Site
  - Dunwoody, Georgia, Forenede Stater, 30338
    - Novartis Investigative Site
  - Peachtree Corners, Georgia, Forenede Stater, 30092
    - Alta Pharmaceutical Research Center
  - Thomasville, Georgia, Forenede Stater, 31792
    - Novartis Investigative Site
  - Thomasville, Georgia, Forenede Stater, 31792
    - Cardiovascular Consultants of S GA
- Illinois
  - Chicago, Illinois, Forenede Stater, 60612
    - Rush University Medical Center
  - Park Ridge, Illinois, Forenede Stater, 60068
    - Novartis Investigative Site
  - Park Ridge, Illinois, Forenede Stater, 60068
    - Advocate Lutheran General Childrens Hospital
- Indiana
  - Indianapolis, Indiana, Forenede Stater, 46202 4800
    - Novartis Investigative Site
  - Indianapolis, Indiana, Forenede Stater, 46202 4800
    - Krannert Institute of Cardiology
- Iowa
  - Iowa City, Iowa, Forenede Stater, 52242
    - Novartis Investigative Site
  - Iowa City, Iowa, Forenede Stater, 52242
    - Uni Of Iowa Hospitals And Clinics
- Kansas
  - Kansas City, Kansas, Forenede Stater, 66160
    - Novartis Investigative Site
  - Kansas City, Kansas, Forenede Stater, 66160
    - University of Kansas Hospital
  - Topeka, Kansas, Forenede Stater, 66606
    - Novartis Investigative Site
  - Topeka, Kansas, Forenede Stater, 66606
    - Cotton O Neil Clinical Res Center
- Louisiana
  - Alexandria, Louisiana, Forenede Stater, 71301
    - Novartis Investigative Site
  - Alexandria, Louisiana, Forenede Stater, 71301
    - Christus Health Central Louisiana
  - Baton Rouge, Louisiana, Forenede Stater, 70808
    - Novartis Investigative Site
  - Bogalusa, Louisiana, Forenede Stater, 70427
    - Novartis Investigative Site
  - Bossier City, Louisiana, Forenede Stater, 71111
    - Novartis Investigative Site
  - Covington, Louisiana, Forenede Stater, 70433
    - Novartis Investigative Site
  - Covington, Louisiana, Forenede Stater, 70433
    - Cardiovascular Associates Research
  - Covington, Louisiana, Forenede Stater, 70433
    - Louisiana Heart Center Research
  - Eunice, Louisiana, Forenede Stater, 70535
    - Novartis Investigative Site
  - Hammond, Louisiana, Forenede Stater, 70403
    - Novartis Investigative Site
  - Hammond, Louisiana, Forenede Stater, 70403
    - Heart Clinic of Hammond
  - Houma, Louisiana, Forenede Stater, 70360
    - Novartis Investigative Site
  - Houma, Louisiana, Forenede Stater, 70360
    - CV Institute of the South
  - Lafayette, Louisiana, Forenede Stater, 70501
    - Horizon Research Grp
  - Metairie, Louisiana, Forenede Stater, 70006
    - Novartis Investigative Site
  - Metairie, Louisiana, Forenede Stater, 70006
    - Omega Clinical Research
  - New Orleans, Louisiana, Forenede Stater, 70115
    - Novartis Investigative Site
  - New Orleans, Louisiana, Forenede Stater, 70112
    - Tulane Uni Health Sciences Center
  - New Orleans, Louisiana, Forenede Stater, 70115
    - Crescent City Physicians Inc
  - Opelousas, Louisiana, Forenede Stater, 70570
    - Novartis Investigative Site
  - Opelousas, Louisiana, Forenede Stater, 70570
    - CV Ins of the South
  - Shreveport, Louisiana, Forenede Stater, 71105
    - Novartis Investigative Site
  - Shreveport, Louisiana, Forenede Stater, 71105
    - Grace Research Llc
  - Slidell, Louisiana, Forenede Stater, 70458
    - Novartis Investigative Site
  - Slidell, Louisiana, Forenede Stater, 70458
    - Louisiana Heart Center Research
  - Zachary, Louisiana, Forenede Stater, 70791
    - Southern Clinical Research
  - Zachary, Louisiana, Forenede Stater, 70791
    - Novartis Investigative Site
- Maine
  - Scarborough, Maine, Forenede Stater, 04074
    - Novartis Investigative Site
  - Scarborough, Maine, Forenede Stater, 04074
    - Maine Health Cardiology
- Maryland
  - Baltimore, Maryland, Forenede Stater, 21201
    - University of Maryland
  - Baltimore, Maryland, Forenede Stater, 21201
    - Novartis Investigative Site
  - Baltimore, Maryland, Forenede Stater, 21287
    - Novartis Investigative Site
  - Baltimore, Maryland, Forenede Stater, 21209
    - Novartis Investigative Site
  - Baltimore, Maryland, Forenede Stater, 21209
    - Sinai Ct for Throm Res and Drug Dev
  - Baltimore, Maryland, Forenede Stater, 21287
    - Johns Hopkins Univ School of Med
  - Columbia, Maryland, Forenede Stater, 21044
    - Johns Hopkins University
  - Columbia, Maryland, Forenede Stater, 21044
    - Novartis Investigative Site
  - Ft. Washington, Maryland, Forenede Stater, 20744
    - Anderson Medical Research
  - Ft. Washington, Maryland, Forenede Stater, 20744
    - Novartis Investigative Site
  - Rockville, Maryland, Forenede Stater, 20850
    - Novartis Investigative Site
  - Rockville, Maryland, Forenede Stater, 20850
    - Adventist HealthCare Shady Grove Medical Center
- Massachusetts
  - Boston, Massachusetts, Forenede Stater, 02115
    - Novartis Investigative Site
  - Boston, Massachusetts, Forenede Stater, 02114-2696
    - Novartis Investigative Site
  - Boston, Massachusetts, Forenede Stater, 02115
    - Brigham and Womens Hosp Harvard Med School
  - Boston, Massachusetts, Forenede Stater, 02114 2696
    - MGH
- Michigan
  - Detroit, Michigan, Forenede Stater, 48202
    - Henry Ford Hospital
  - Detroit, Michigan, Forenede Stater, 48202
    - Novartis Investigative Site
  - Detroit, Michigan, Forenede Stater, 48201
    - Wayne State University
  - Detroit, Michigan, Forenede Stater, 48201
    - Novartis Investigative Site
  - Flint, Michigan, Forenede Stater, 48504
    - Novartis Investigative Site
  - Flint, Michigan, Forenede Stater, 48504
    - AA Medical Research Center
  - Grand Blanc, Michigan, Forenede Stater, 48439
    - Genesys Regional Medical Center
  - Grand Blanc, Michigan, Forenede Stater, 48439
    - Novartis Investigative Site
  - Kalamazoo, Michigan, Forenede Stater, 49008
    - Novartis Investigative Site
  - Kalamazoo, Michigan, Forenede Stater, 49008
    - Western Michigan University
  - Petoskey, Michigan, Forenede Stater, 49770
    - Novartis Investigative Site
  - Petoskey, Michigan, Forenede Stater, 49770
    - McLaren Ctr Research Innovation
  - Saginaw, Michigan, Forenede Stater, 48601
    - Novartis Investigative Site
  - Saginaw, Michigan, Forenede Stater, 48601
    - Central Michigan University
  - Wyoming, Michigan, Forenede Stater, 49519
    - Novartis Investigative Site
  - Wyoming, Michigan, Forenede Stater, 49519
    - Metro Health Univ of MI Health
- Minnesota
  - Maplewood, Minnesota, Forenede Stater, 55109
    - Saint Johns Hospital
  - Minneapolis, Minnesota, Forenede Stater, 55455
    - University of Minnesota
  - Minneapolis, Minnesota, Forenede Stater, 55455
    - Novartis Investigative Site
  - Minneapolis, Minnesota, Forenede Stater, 55407
    - Minneapolis Heart Institute
  - Minneapolis, Minnesota, Forenede Stater, 55407
    - Novartis Investigative Site
- Mississippi
  - Belzoni, Mississippi, Forenede Stater, 39038
    - Belzoni Clinical Research
  - Belzoni, Mississippi, Forenede Stater, 39038
    - Novartis Investigative Site
  - Southaven, Mississippi, Forenede Stater, 38671
    - Novartis Investigative Site
  - Southaven, Mississippi, Forenede Stater, 38671
    - Stern Cardiovascular Foundation Inc
  - Yazoo City, Mississippi, Forenede Stater, 39194
    - Novartis Investigative Site
- Missouri
  - City of Saint Peters, Missouri, Forenede Stater, 63303
    - StudyMetrix Research
  - City of Saint Peters, Missouri, Forenede Stater, 63303
    - Novartis Investigative Site
  - St Louis, Missouri, Forenede Stater, 63110
    - Novartis Investigative Site
  - St Louis, Missouri, Forenede Stater, 63110
    - Washington Univ School Of Medicine
  - St Louis, Missouri, Forenede Stater, 63128
    - Mercy South
  - St Louis, Missouri, Forenede Stater, 63141
    - Mercy Hospital St Louis
- Nebraska
  - Lincoln, Nebraska, Forenede Stater, 68526
    - Novartis Investigative Site
  - Omaha, Nebraska, Forenede Stater, 68114
    - Novartis Investigative Site
  - Omaha, Nebraska, Forenede Stater, 68114
    - Quality Clinical Research
- New Hampshire
  - Lebanon, New Hampshire, Forenede Stater, 03756
    - Dartmouth Hitchcock Medical Center
  - Lebanon, New Hampshire, Forenede Stater, 03756
    - Novartis Investigative Site
- New Jersey
  - Ridgewood, New Jersey, Forenede Stater, 07450
    - The Valley Hospital
  - Ridgewood, New Jersey, Forenede Stater, 07450
    - Novartis Investigative Site
  - Summit, New Jersey, Forenede Stater, 07901
    - Overlook Medical Center
  - Summit, New Jersey, Forenede Stater, 07901
    - Novartis Investigative Site
- New York
  - Albany, New York, Forenede Stater, 12206
    - Albany Medical College
  - Manhasset, New York, Forenede Stater, 11030
    - Novartis Investigative Site
  - Manhasset, New York, Forenede Stater, 11030
    - Northwell Health
  - New York, New York, Forenede Stater, 10016
    - Novartis Investigative Site
  - New York, New York, Forenede Stater, 10029
    - Novartis Investigative Site
  - New York, New York, Forenede Stater, 10021
    - Weill Cornell Medical Center
  - New York, New York, Forenede Stater, 10021
    - Novartis Investigative Site
  - New York, New York, Forenede Stater, 10075
    - Novartis Investigative Site
  - New York, New York, Forenede Stater, 10029
    - Icahn School of Med at Mt Sinai
  - New York, New York, Forenede Stater, 43210
    - Lenox Hill Hospital
  - New York, New York, Forenede Stater, 10016
    - New York Uni Med Ctr
  - Riverhead, New York, Forenede Stater, 11901
    - Northwell Health Physician Peconic
  - Rochester, New York, Forenede Stater, 14642
    - Strong Memorial Hospital
  - Rochester, New York, Forenede Stater, 14621
    - Rochester Regional Health
  - Southampton, New York, Forenede Stater, 11968
    - Novartis Investigative Site
- North Carolina
  - Charlotte, North Carolina, Forenede Stater, 28204
    - Novartis Investigative Site
  - Charlotte, North Carolina, Forenede Stater, 28204
    - Novant Health Heart Vas Inst
  - Greensboro, North Carolina, Forenede Stater, 27405
    - Novartis Investigative Site
  - Greensboro, North Carolina, Forenede Stater, 27405
    - Medication Management LLC
  - High Point, North Carolina, Forenede Stater, 27262
    - Novartis Investigative Site
  - Raleigh, North Carolina, Forenede Stater, 27609
    - Accellacare US Inc
  - Sanford, North Carolina, Forenede Stater, 27330
    - Novartis Investigative Site
  - Shelby, North Carolina, Forenede Stater, 28150
    - Novartis Investigative Site
  - Shelby, North Carolina, Forenede Stater, 28150
    - Jones Family Practice PA
  - Winston-Salem, North Carolina, Forenede Stater, 27157
    - Novartis Investigative Site
  - Winston-Salem, North Carolina, Forenede Stater, 27157
    - Wake Forest University Baptist Medical Center
- Ohio
  - Akron, Ohio, Forenede Stater, 44304
    - Novartis Investigative Site
  - Akron, Ohio, Forenede Stater, 44309
    - Akron Hospital Summa Health System
  - Canton, Ohio, Forenede Stater, 44710
    - Novartis Investigative Site
  - Canton, Ohio, Forenede Stater, 44710
    - Aultman Hospital
  - Cincinnati, Ohio, Forenede Stater, 45267
    - University of Cincinnati
  - Cincinnati, Ohio, Forenede Stater, 45267
    - Novartis Investigative Site
  - Cincinnati, Ohio, Forenede Stater, 45219
    - Novartis Investigative Site
  - Cincinnati, Ohio, Forenede Stater, 45246
    - Novartis Investigative Site
  - Cincinnati, Ohio, Forenede Stater, 45246
    - Velocity Clin Research Springdale
  - Cincinnati, Ohio, Forenede Stater, 45219
    - Lindner Ctr At The Christ Hosp
  - Cleveland, Ohio, Forenede Stater, 44195
    - Cleveland Clinic Foundation
  - Cleveland, Ohio, Forenede Stater, 44195
    - Novartis Investigative Site
  - Columbus, Ohio, Forenede Stater, 43210
    - Ohio State University
  - Columbus, Ohio, Forenede Stater, 43210
    - Novartis Investigative Site
  - Marion, Ohio, Forenede Stater, 43302
    - Rama Research LLC
  - Marion, Ohio, Forenede Stater, 43302
    - Novartis Investigative Site
- Oregon
  - Portland, Oregon, Forenede Stater, 97239
    - Novartis Investigative Site
  - Portland, Oregon, Forenede Stater, 97239
    - Oregon Health Sciences University
- Pennsylvania
  - Lancaster, Pennsylvania, Forenede Stater, 17603
    - Novartis Investigative Site
  - Lancaster, Pennsylvania, Forenede Stater, 17603
    - Lancaster General Health
  - Philadelphia, Pennsylvania, Forenede Stater, 19104
    - Novartis Investigative Site
  - Philadelphia, Pennsylvania, Forenede Stater, 19104
    - Perelman School of Medicine
  - Pittsburgh, Pennsylvania, Forenede Stater, 15212
    - Allegheny General Hospital
  - Yardley, Pennsylvania, Forenede Stater, 19067
    - Novartis Investigative Site
  - Yardley, Pennsylvania, Forenede Stater, 19067
    - Cardiology Consultants of Philadelphia
- Rhode Island
  - Providence, Rhode Island, Forenede Stater, 02906
    - Miriam Hospital
  - Providence, Rhode Island, Forenede Stater, 02906
    - Novartis Investigative Site
- South Carolina
  - Fort Mill, South Carolina, Forenede Stater, 29707
    - Novartis Investigative Site
  - Fort Mill, South Carolina, Forenede Stater, 29707
    - Piedmont Research Partners LLC
  - Summerville, South Carolina, Forenede Stater, 29485
    - Palmetto Clinical Research
  - Summerville, South Carolina, Forenede Stater, 29485
    - Novartis Investigative Site
- South Dakota
  - Rapid City, South Dakota, Forenede Stater, 57701
    - Novartis Investigative Site
  - Rapid City, South Dakota, Forenede Stater, 57701
    - Monument Health Clinical Research
- Tennessee
  - Germantown, Tennessee, Forenede Stater, 38138
    - Novartis Investigative Site
  - Germantown, Tennessee, Forenede Stater, 38138
    - The Stern Cardiovascular Foundation
  - Jackson, Tennessee, Forenede Stater, 38301
    - Novartis Investigative Site
  - Jackson, Tennessee, Forenede Stater, 38301
    - Apex Cardiology Research Associates of Jackson
  - Nashville, Tennessee, Forenede Stater, 37232
    - Novartis Investigative Site
  - Nashville, Tennessee, Forenede Stater, 37232
    - Vanderbilt Univ Medi Cen
  - Powell, Tennessee, Forenede Stater, 37849
    - Novartis Investigative Site
  - Powell, Tennessee, Forenede Stater, 37849
    - Cardiovascular Res of Knoxville LLC
- Texas
  - Dallas, Texas, Forenede Stater, 75390
    - UT Southwestern Medical Center
  - Dallas, Texas, Forenede Stater, 75235
    - Novartis Investigative Site
  - Dallas, Texas, Forenede Stater, 75226
    - Novartis Investigative Site
  - Dallas, Texas, Forenede Stater, 75231
    - Novartis Investigative Site
  - Dallas, Texas, Forenede Stater, 75231
    - North Texas Endocrine Center
  - Dallas, Texas, Forenede Stater, 75226
    - Soltero Cardiovascular Research Center
  - Dallas, Texas, Forenede Stater, 75235
    - SW Family Medicine Associates
  - Houston, Texas, Forenede Stater, 77030
    - Baylor College of Medicine
  - Houston, Texas, Forenede Stater, 77030
    - Novartis Investigative Site
  - Livingston, Texas, Forenede Stater, 77351
    - Novartis Investigative Site
  - Marshall, Texas, Forenede Stater, 75670
    - Grace Research
  - Temple, Texas, Forenede Stater, 76508
    - Novartis Investigative Site
  - Tomball, Texas, Forenede Stater, 77375
    - Novartis Investigative Site
  - Tomball, Texas, Forenede Stater, 77375
    - Northwest Houston Clinical Research PLLC
- Utah
  - Bountiful, Utah, Forenede Stater, 84010
    - Progressive Clinical Research
  - Bountiful, Utah, Forenede Stater, 84010
    - Novartis Investigative Site
  - Murray, Utah, Forenede Stater, 84107
    - Intermountain Medical Center
  - Murray, Utah, Forenede Stater, 84107
    - Novartis Investigative Site
  - Salt Lake City, Utah, Forenede Stater, 84132-0001
    - The University of Utah
- Virginia
  - Danville, Virginia, Forenede Stater, 24541
    - Novartis Investigative Site
  - Falls Church, Virginia, Forenede Stater, 22042
    - Inova Fairfax Hospital
  - Falls Church, Virginia, Forenede Stater, 22042
    - Virginia Heart
  - Falls Church, Virginia, Forenede Stater, 22042
    - Novartis Investigative Site
  - Manassas, Virginia, Forenede Stater, 20109
    - Novartis Investigative Site
  - Manassas, Virginia, Forenede Stater, 20109
    - Carient Heart and Vascular
  - Norfolk, Virginia, Forenede Stater, 23504
    - York Clinical Research
  - Norfolk, Virginia, Forenede Stater, 23510
    - Novartis Investigative Site
  - Richmond, Virginia, Forenede Stater, 23219
    - Dominion Medical Associates
  - Richmond, Virginia, Forenede Stater, 23219
    - Novartis Investigative Site
- Washington
  - Seattle, Washington, Forenede Stater, 98104
    - Harborview Medical Center
  - Seattle, Washington, Forenede Stater, 98104
    - Novartis Investigative Site
  - Seattle, Washington, Forenede Stater, 98122
    - Novartis Investigative Site
  - Seattle, Washington, Forenede Stater, 98195
    - Novartis Investigative Site
  - Seattle, Washington, Forenede Stater, 98122
    - Swedish Medical Center-Cardiovascular Research
  - Seattle, Washington, Forenede Stater, 98195
    - Univ of Washington Medical Center
- West Virginia
  - Morgantown, West Virginia, Forenede Stater, 26506
    - West Virginia University Hospital
- Wisconsin
  - Milwaukee, Wisconsin, Forenede Stater, 53215
    - Novartis Investigative Site
  - Milwaukee, Wisconsin, Forenede Stater, 53215
    - St Luke s Medical Center Aurora
Frankrig
- - Bron, Frankrig, 69677
    - Novartis Investigative Site
  - Chambray-lès-Tours, Frankrig, 37170
    - Novartis Investigative Site
  - Compiègne, Frankrig, 60321
    - Novartis Investigative Site
  - Grenoble, Frankrig, 38043
    - Novartis Investigative Site
  - Le Coudray, Frankrig, 28630
    - Novartis Investigative Site
  - Lille, Frankrig, 59000
    - Novartis Investigative Site
  - Nantes, Frankrig, 44093
    - Novartis Investigative Site
  - Paris, Frankrig, 75015
    - Novartis Investigative Site
  - Paris, Frankrig, 75012
    - Novartis Investigative Site
  - Paris, Frankrig, 75018
    - Novartis Investigative Site
  - Toulouse, Frankrig, 31054
    - Novartis Investigative Site
  - Tourcoing, Frankrig, 59208
    - Novartis Investigative Site
  - Valenciennes, Frankrig, 59300
    - Novartis Investigative Site
Grækenland
- - Athens, Grækenland, 115 27
    - Novartis Investigative Site
  - Athens, Grækenland, 115 21
    - Novartis Investigative Site
  - Athens, Grækenland, 142 33
    - Novartis Investigative Site
  - Chalcis, Grækenland, 341 00
    - Novartis Investigative Site
  - Ioannina, Grækenland, 455 00
    - Novartis Investigative Site
  - Larissa, Grækenland, 411 10
    - Novartis Investigative Site
  - Thessaloniki, Grækenland, 54636
    - Novartis Investigative Site
Guatemala
- - Guatemala City, Guatemala, 01010
    - Novartis Investigative Site
  - Guatemala City, Guatemala, 01011
    - Novartis Investigative Site
- Departamento de Guatemala
  - Guatemala City, Departamento de Guatemala, Guatemala, 01001
    - Novartis Investigative Site
Holland
- - Amersfoort, Holland, 3813 TZ
    - Novartis Investigative Site
  - Enschede, Holland, 7512KZ
    - Novartis Investigative Site
  - Gouda, Holland, 2803 HH
    - Novartis Investigative Site
  - Hardenberg, Holland, 7770 SE
    - Novartis Investigative Site
  - Utrecht, Holland, 3584 CX
    - Novartis Investigative Site
  - Venlo, Holland, 5912 BL
    - Novartis Investigative Site
- Gelderland
  - Apeldoorn, Gelderland, Holland, 7334 DZ
    - Novartis Investigative Site
  - Arnhem, Gelderland, Holland, 6815 AD
    - Novartis Investigative Site
  - Nijmegen, Gelderland, Holland, 6500HB
    - Novartis Investigative Site
  - Tiel, Gelderland, Holland, 4002 WP
    - Novartis Investigative Site
- Gerlderland
  - Nijmegen, Gerlderland, Holland, 6532 SZ
    - Novartis Investigative Site
- Limburg
  - Heerlen, Limburg, Holland, 6419 PC
    - Novartis Investigative Site
- North Brabant
  - Tilburg, North Brabant, Holland, 5042 AD
    - Novartis Investigative Site
- North Holland
  - Alkmaar, North Holland, Holland, 1815 JD
    - Novartis Investigative Site
  - Amsterdam, North Holland, Holland, 1090 HM
    - Novartis Investigative Site
  - Amsterdam, North Holland, Holland, 1105 AZ
    - Novartis Investigative Site
  - Heemstede, North Holland, Holland, 2035 RC
    - Novartis Investigative Site
- Overijssel
  - Deventer, Overijssel, Holland, 7416 SE
    - Novartis Investigative Site
  - Zwolle, Overijssel, Holland, 8025 AB
    - Novartis Investigative Site
- Provincie Friesland
  - Sneek, Provincie Friesland, Holland, 8601 ZK
    - Novartis Investigative Site
- Provincie Groningen
  - Groningen, Provincie Groningen, Holland, 9728 NZ
    - Novartis Investigative Site
- South Holland
  - Delft, South Holland, Holland, 2625 AD
    - Novartis Investigative Site
  - Leiden, South Holland, Holland, 2333 ZA
    - Novartis Investigative Site
  - Leiderdorp, South Holland, Holland, 2353 GA
    - Novartis Investigative Site
  - The Hague, South Holland, Holland, 2545 AA
    - Novartis Investigative Site
Hong Kong
- - Hong Kong, Hong Kong, 999077
    - Novartis Investigative Site
  - Shatin, Hong Kong, 999077
    - Novartis Investigative Site
Indien
- - New Delhi, Indien, 110025
    - Novartis Investigative Site
- Andhra Pradesh
  - Guntur, Andhra Pradesh, Indien, 522001
    - Novartis Investigative Site
  - Hyderabad, Andhra Pradesh, Indien, 500033
    - Novartis Investigative Site
- Gujarat
  - Ahmedabad, Gujarat, Indien, 380054
    - Novartis Investigative Site
  - Ahmedabad, Gujarat, Indien, 380060
    - Novartis Investigative Site
  - Vadodara, Gujarat, Indien, 390022
    - Novartis Investigative Site
- Karnataka
  - Belagavi, Karnataka, Indien, 590010
    - Novartis Investigative Site
  - Mangalore, Karnataka, Indien, 575018
    - Novartis Investigative Site
  - Manipal, Karnataka, Indien, 576104
    - Novartis Investigative Site
  - Mysore, Karnataka, Indien, 570015
    - Novartis Investigative Site
- Kerala
  - Kochi, Kerala, Indien, 682027
    - Novartis Investigative Site
  - Kochi, Kerala, Indien, 682041
    - Novartis Investigative Site
  - Kochi, Kerala, Indien, 682018
    - Novartis Investigative Site
  - Kozhikode, Kerala, Indien, 673008
    - Novartis Investigative Site
- Maharashtra
  - Mumbai, Maharashtra, Indien, 401107
    - Novartis Investigative Site
  - Nagpur, Maharashtra, Indien, 440009
    - Novartis Investigative Site
  - Nagpur, Maharashtra, Indien, 440008
    - Novartis Investigative Site
  - Nagpur, Maharashtra, Indien, 440012
    - Novartis Investigative Site
  - Nagpur, Maharashtra, Indien, 440033
    - Novartis Investigative Site
  - Nashik, Maharashtra, Indien, 422005
    - Novartis Investigative Site
  - Pune, Maharashtra, Indien, 411004
    - Novartis Investigative Site
  - Pune, Maharashtra, Indien, 411001
    - Novartis Investigative Site
  - Pune, Maharashtra, Indien, 411045
    - Novartis Investigative Site
- National Capital Territory of Delhi
  - New Delhi, National Capital Territory of Delhi, Indien, 110060
    - Novartis Investigative Site
  - New Delhi, National Capital Territory of Delhi, Indien, 110075
    - Novartis Investigative Site
- Rajasthan
  - Bikaner, Rajasthan, Indien, 334003
    - Novartis Investigative Site
- Tamil Nadu
  - Chennai, Tamil Nadu, Indien, 600006
    - Novartis Investigative Site
  - Coimbatore, Tamil Nadu, Indien, 641037
    - Novartis Investigative Site
  - Coimbatore, Tamil Nadu, Indien, 641009
    - Novartis Investigative Site
- Telangana
  - Hyderabad, Telangana, Indien, 500082
    - Novartis Investigative Site
  - Hyderabad, Telangana, Indien, 500034
    - Novartis Investigative Site
  - Secunderabad, Telangana, Indien, 500003
    - Novartis Investigative Site
- Uttar Pradesh
  - Ghaziabad, Uttar Pradesh, Indien, 201012
    - Novartis Investigative Site
  - Lucknow, Uttar Pradesh, Indien, 226003
    - Novartis Investigative Site
  - Varanasi, Uttar Pradesh, Indien, 221010
    - Novartis Investigative Site
- Uttarakhand
  - Dehradun, Uttarakhand, Indien, 248001
    - Novartis Investigative Site
Island
- - Kopavogur, Island, 201
    - Novartis Investigative Site
  - Reykjavik, Island, 101
    - Novartis Investigative Site
Israel
- - Beersheba, Israel, 8457108
    - Novartis Investigative Site
  - Haifa, Israel, 3436212
    - Novartis Investigative Site
  - Haifa, Israel, 3104802
    - Novartis Investigative Site
  - Holon, Israel, 5822012
    - Novartis Investigative Site
  - Jerusalem, Israel, 9112001
    - Novartis Investigative Site
  - Petah Tikva, Israel, 4941492
    - Novartis Investigative Site
  - Ramat Gan, Israel, 5265601
    - Novartis Investigative Site
Italien
- - Naples, Italien, 80131
    - Novartis Investigative Site
- AN
  - Ancona, AN, Italien, 60128
    - Novartis Investigative Site
- BG
  - Bergamo, BG, Italien, 24127
    - Novartis Investigative Site
- BO
  - Bologna, BO, Italien, 40138
    - Novartis Investigative Site
- BS
  - Brescia, BS, Italien, 25123
    - Novartis Investigative Site
- FE
  - Cona, FE, Italien, 44124
    - Novartis Investigative Site
- FI
  - Florence, FI, Italien, 50134
    - Novartis Investigative Site
- IS
  - Pozzilli, IS, Italien, 86077
    - Novartis Investigative Site
- MI
  - Milan, MI, Italien, 20162
    - Novartis Investigative Site
  - Milan, MI, Italien, 20132
    - Novartis Investigative Site
  - Milan, MI, Italien, 20138
    - Novartis Investigative Site
  - Milan, MI, Italien, 20149
    - Novartis Investigative Site
  - Rozzano, MI, Italien, 20089
    - Novartis Investigative Site
- PA
  - Palermo, PA, Italien, 90127
    - Novartis Investigative Site
- PG
  - Perugia, PG, Italien, 06129
    - Novartis Investigative Site
- PI
  - Pisa, PI, Italien, 56124
    - Novartis Investigative Site
  - Pisa, PI, Italien, 56126
    - Novartis Investigative Site
- RM
  - Roma, RM, Italien, 00161
    - Novartis Investigative Site
  - Roma, RM, Italien, 00189
    - Novartis Investigative Site
- SA
  - Salerno, SA, Italien, 84131
    - Novartis Investigative Site
- VA
  - Varese, VA, Italien, 21100
    - Novartis Investigative Site
Japan
- - Ishikawa, Japan, 9208641
    - Novartis Investigative Site
- Aichi-ken
  - Nagoya, Aichi-ken, Japan, 453-8511
    - Novartis Investigative Site
  - Seto, Aichi-ken, Japan, 4898642
    - Novartis Investigative Site
- Aomori
  - Hirosaki, Aomori, Japan, 0368563
    - Novartis Investigative Site
- Chiba
  - Asahi, Chiba, Japan, 289-2511
    - Novartis Investigative Site
  - Funabashi, Chiba, Japan, 273-8588
    - Novartis Investigative Site
  - Matsudo, Chiba, Japan, 270-2251
    - Novartis Investigative Site
- Fukuoka
  - Fukuoka, Fukuoka, Japan, 8140180
    - Novartis Investigative Site
  - Kitakyushu, Fukuoka, Japan, 8028555
    - Novartis Investigative Site
- Gifu
  - Ōgaki, Gifu, Japan, 503-8502
    - Novartis Investigative Site
- Hiroshima
  - Kure, Hiroshima, Japan, 737-0023
    - Novartis Investigative Site
- Ibaraki
  - Tsuchiura, Ibaraki, Japan, 300-0028
    - Novartis Investigative Site
- Ishikawa-ken
  - Kahoku-gun, Ishikawa-ken, Japan, 920-0293
    - Novartis Investigative Site
  - Komatsu, Ishikawa-ken, Japan, 923-0961
    - Novartis Investigative Site
- Kagawa-ken
  - Takamatsu, Kagawa-ken, Japan, 7608557
    - Novartis Investigative Site
- Kanagawa
  - Kawasaki, Kanagawa, Japan, 2120021
    - Novartis Investigative Site
  - Sagamihara, Kanagawa, Japan, 252-0375
    - Novartis Investigative Site
  - Yokohama, Kanagawa, Japan, 232-0024
    - Novartis Investigative Site
  - Yokohama, Kanagawa, Japan, 2360037
    - Novartis Investigative Site
- Miyagi
  - Sendai, Miyagi, Japan, 981-0914
    - Novartis Investigative Site
- Miyazaki
  - Miyhazaki, Miyazaki, Japan, 8802102
    - Novartis Investigative Site
- Niigata
  - Nagaoka, Niigata, Japan, 940-8621
    - Novartis Investigative Site
- Osaka
  - Osaka, Osaka, Japan, 543-8922
    - Novartis Investigative Site
  - Osaka, Osaka, Japan, 5300001
    - Novartis Investigative Site
- Saitama
  - Kawaguchi, Saitama, Japan, 3330842
    - Novartis Investigative Site
  - Sayama, Saitama, Japan, 350-1305
    - Novartis Investigative Site
- Shiga
  - Ōmihachiman, Shiga, Japan, 523-0082
    - Novartis Investigative Site
- Tokyo
  - Bunkyo Ku, Tokyo, Japan, 1138431
    - Novartis Investigative Site
  - Chuo Ku, Tokyo, Japan, 104-8560
    - Novartis Investigative Site
  - Chuo-ku, Tokyo, Japan, 1030027
    - Novartis Investigative Site
  - Hachiōji, Tokyo, Japan, 192-0918
    - Novartis Investigative Site
  - Itabashi-ku, Tokyo, Japan, 1738610
    - Novartis Investigative Site
  - Shinagawa-ku, Tokyo, Japan, 1428666
    - Novartis Investigative Site
  - Toshima-ku, Tokyo, Japan, 171-0014
    - Novartis Investigative Site
  - Ōta-ku, Tokyo, Japan, 1438541
    - Novartis Investigative Site
Kina
- - Beijing, Kina, 100730
    - Novartis Investigative Site
  - Beijing, Kina, 100050
    - Novartis Investigative Site
  - Beijing, Kina, 100191
    - Novartis Investigative Site
  - Shanghai, Kina, 200025
    - Novartis Investigative Site
  - Shanghai, Kina, 200040
    - Novartis Investigative Site
  - Shanghai, Kina, 200120
    - Novartis Investigative Site
  - Shanghai, Kina, 200065
    - Novartis Investigative Site
  - Tianjin, Kina, 300052
    - Novartis Investigative Site
  - Tianjin, Kina, 300121
    - Novartis Investigative Site
  - Tianjin, Kina, 030045
    - Novartis Investigative Site
  - Xiamen, Kina, 361004
    - Novartis Investigative Site
- Beijing Municipality
  - Beijing, Beijing Municipality, Kina, 100013
    - Novartis Investigative Site
- Gansu
  - Lanzhou, Gansu, Kina, 730030
    - Novartis Investigative Site
- Guangdong
  - Foshan, Guangdong, Kina, 528000
    - Novartis Investigative Site
  - Guangzhou, Guangdong, Kina, 510080
    - Novartis Investigative Site
  - Guangzhou, Guangdong, Kina, 510030
    - Novartis Investigative Site
- Heilongjiang
  - Harbin, Heilongjiang, Kina, 150000
    - Novartis Investigative Site
- Hunan
  - Changsha, Hunan, Kina, 410008
    - Novartis Investigative Site
  - Changsha, Hunan, Kina, 410011
    - Novartis Investigative Site
  - Changsha, Hunan, Kina, 410003
    - Novartis Investigative Site
- Inner Mongolia
  - Baotou, Inner Mongolia, Kina, 014040
    - Novartis Investigative Site
- Jiangsu
  - Nanjing, Jiangsu, Kina, 210029
    - Novartis Investigative Site
  - Nanjing, Jiangsu, Kina, 210009
    - Novartis Investigative Site
  - Nanjing, Jiangsu, Kina, 211166
    - Novartis Investigative Site
  - Suzhou, Jiangsu, Kina, 215004
    - Novartis Investigative Site
  - Xuzhou, Jiangsu, Kina, 221003
    - Novartis Investigative Site
- Jilin
  - Changchun, Jilin, Kina, 130021
    - Novartis Investigative Site
- Liaoning
  - Dalian, Liaoning, Kina, 116011
    - Novartis Investigative Site
  - Shenyang, Liaoning, Kina, 110016
    - Novartis Investigative Site
  - Shenyang, Liaoning, Kina, 110004
    - Novartis Investigative Site
- Shandong
  - Jinan, Shandong, Kina, 250013
    - Novartis Investigative Site
- Shanxi
  - Xian, Shanxi, Kina, 710061
    - Novartis Investigative Site
- Sichuan
  - Chengdu, Sichuan, Kina, 610041
    - Novartis Investigative Site
- Xinjiang
  - Ürümqi, Xinjiang, Kina, 830054
    - Novartis Investigative Site
- Zhejiang
  - Hangzhou, Zhejiang, Kina, 310016
    - Novartis Investigative Site
  - Hangzhou, Zhejiang, Kina, 310014
    - Novartis Investigative Site
  - Wenzhou, Zhejiang, Kina, 325000
    - Novartis Investigative Site
Mexico
- - Culiacan Sinaloa, Mexico, 80230
    - Novartis Investigative Site
  - Distrito Federal, Mexico, 14080
    - Novartis Investigative Site
- Aguascalientes
  - Aguascalientes, Aguascalientes, Mexico, 20230
    - Novartis Investigative Site
- Morelos
  - Cuernavaca, Morelos, Mexico, 62250
    - Novartis Investigative Site
- San Luis Potosí
  - San Luis Potosí City, San Luis Potosí, Mexico, 78200
    - Novartis Investigative Site
Norge
- - Oslo, Norge, 0514
    - Novartis Investigative Site
  - Skedsmokorset, Norge, 2020
    - Novartis Investigative Site
Peru
- Lima region
  - San Miguel, Lima region, Peru, 32
    - Novartis Investigative Site
Polen
- - Bielsko-Biala, Polen, 43-316
    - Novartis Investigative Site
  - Chrzanów, Polen, 32-500
    - Novartis Investigative Site
  - Gdansk, Polen, 80-214
    - Novartis Investigative Site
  - Gdynia, Polen, 81-157
    - Novartis Investigative Site
  - Krakow, Polen, 30-082
    - Novartis Investigative Site
  - Krakow, Polen, 31-216
    - Novartis Investigative Site
  - Kędzierzyn-Koźle, Polen, 47 220
    - Novartis Investigative Site
  - Lodz, Polen, 93-338
    - Novartis Investigative Site
  - Lodz, Polen, 91-347
    - Novartis Investigative Site
  - Poznan, Polen, 60-589
    - Novartis Investigative Site
  - Sochaczew, Polen, 96-500
    - Novartis Investigative Site
  - Tarnów, Polen, 33-100
    - Novartis Investigative Site
Portugal
- - Coimbra, Portugal, 3004-561
    - Novartis Investigative Site
  - Guimarães, Portugal, 4835-044
    - Novartis Investigative Site
  - Setúbal, Portugal, 2910-549
    - Novartis Investigative Site
Puerto Rico
- - Ponce, Puerto Rico, 00717-1322
    - Novartis Investigative Site
  - Ponce, Puerto Rico, 00717-1322
    - Research and Cardiovascular Corp
Rumænien
- - Brasov, Rumænien, 500283
    - Novartis Investigative Site
  - Bucharest, Rumænien, 050098
    - Novartis Investigative Site
  - Bucharest, Rumænien, 010192
    - Novartis Investigative Site
  - Iași, Rumænien, 700503
    - Novartis Investigative Site
- Buzău
  - Buzău, Buzău, Rumænien, 120133
    - Novartis Investigative Site
- Dolj
  - Craiova, Dolj, Rumænien, 200513
    - Novartis Investigative Site
- Jud Iasi
  - Iași, Jud Iasi, Rumænien, 700732
    - Novartis Investigative Site
- Maramureş
  - Baia Mare, Maramureş, Rumænien, 430222
    - Novartis Investigative Site
  - Baia Mare, Maramureş, Rumænien, 430123
    - Novartis Investigative Site
- Timiș County
  - Timișoara, Timiș County, Rumænien, 300362
    - Novartis Investigative Site
Rusland
- - Chelyabinsk, Rusland, 454047
    - Novartis Investigative Site
  - Ivanovo, Rusland, 153012
    - Novartis Investigative Site
  - Izhevsk, Rusland, 426061
    - Novartis Investigative Site
  - Kemerovo, Rusland, 650002
    - Novartis Investigative Site
  - Kirov, Rusland, 610035
    - Novartis Investigative Site
  - Krasnodar, Rusland, 350086
    - Novartis Investigative Site
  - Moscow, Rusland, 117997
    - Novartis Investigative Site
  - Moscow, Rusland, 117198
    - Novartis Investigative Site
  - Moscow, Rusland, 127473
    - Novartis Investigative Site
  - Moscow, Rusland, 101990
    - Novartis Investigative Site
  - Moscow, Rusland, 121552
    - Novartis Investigative Site
  - Moscow, Rusland, 141060
    - Novartis Investigative Site
  - Moscow, Rusland, 143420
    - Novartis Investigative Site
  - Novosibirsk, Rusland, 630090
    - Novartis Investigative Site
  - Perm, Rusland, 614097
    - Novartis Investigative Site
  - Petrozavodsk, Rusland, 185019
    - Novartis Investigative Site
  - Rostov-on-Don, Rusland, 344022
    - Novartis Investigative Site
  - Ryazan, Rusland, 390039
    - Novartis Investigative Site
  - Saint Petersburg, Rusland, 197341
    - Novartis Investigative Site
  - Saint Petersburg, Rusland, 195197
    - Novartis Investigative Site
  - Saint Petersburg, Rusland, 197110
    - Novartis Investigative Site
  - Saint Petersburg, Rusland, 191015
    - Novartis Investigative Site
  - Saint Petersburg, Rusland, 192007
    - Novartis Investigative Site
  - Saint Petersburg, Rusland, 194354
    - Novartis Investigative Site
  - Saint Petersburg, Rusland, 196143
    - Novartis Investigative Site
  - Saint Petersburg, Rusland, 197136
    - Novartis Investigative Site
  - Samara, Rusland, 443070
    - Novartis Investigative Site
  - Saratov, Rusland, 410012
    - Novartis Investigative Site
  - Saratov, Rusland, 410028
    - Novartis Investigative Site
  - Sochy, Rusland, 354002
    - Novartis Investigative Site
  - Tomsk, Rusland, 634009
    - Novartis Investigative Site
  - Ulyanovsk, Rusland, 432063
    - Novartis Investigative Site
  - Vsevolozhsk, Rusland, 188643
    - Novartis Investigative Site
  - Yaroslavl, Rusland, 150062
    - Novartis Investigative Site
  - Yekaterinburg, Rusland, 620144
    - Novartis Investigative Site
  - Yekaterinburg, Rusland, 620028
    - Novartis Investigative Site
  - Yekaterinburg, Rusland, 620137
    - Novartis Investigative Site
- Russia
  - Saint Petersburg, Russia, Rusland, 195197
    - Novartis Investigative Site
  - Saint Petersburg, Russia, Rusland, 198328
    - Novartis Investigative Site
Schweiz
- - Basel, Schweiz, 4031
    - Novartis Investigative Site
  - Bern, Schweiz, 3010
    - Novartis Investigative Site
  - Geneva, Schweiz, 1211
    - Novartis Investigative Site
  - Lausanne, Schweiz, 1011
    - Novartis Investigative Site
  - Liestal, Schweiz, 4410
    - Novartis Investigative Site
  - Zurich, Schweiz, 8091
    - Novartis Investigative Site
Slovakiet
- - Banská Bystrica, Slovakiet, 974 05
    - Novartis Investigative Site
  - Bardejov, Slovakiet, 085 01
    - Novartis Investigative Site
  - Bratislava, Slovakiet, 833 48
    - Novartis Investigative Site
  - Bratislava, Slovakiet, 821 07
    - Novartis Investigative Site
  - Bratislava, Slovakiet, 833 05
    - Novartis Investigative Site
  - Bratislava, Slovakiet, 851 07
    - Novartis Investigative Site
  - Bratislava, Slovakiet, 851 01
    - Novartis Investigative Site
  - Bratislava, Slovakiet, 841 08
    - Novartis Investigative Site
  - Dolný Kubín, Slovakiet, 026 01
    - Novartis Investigative Site
  - Handlová, Slovakiet, 972 51
    - Novartis Investigative Site
  - Kláštor pod Znievom, Slovakiet, 038 43
    - Novartis Investigative Site
  - Komárno, Slovakiet, 945 01
    - Novartis Investigative Site
  - Komárno, Slovakiet, 945 05
    - Novartis Investigative Site
  - Košice, Slovakiet, 040 01
    - Novartis Investigative Site
  - Košice, Slovakiet, 040 22
    - Novartis Investigative Site
  - Lučenec, Slovakiet, 984 01
    - Novartis Investigative Site
  - Nitra, Slovakiet, 949 01
    - Novartis Investigative Site
  - Nitra, Slovakiet, 950 01
    - Novartis Investigative Site
  - Nitra, Slovakiet, 949 11
    - Novartis Investigative Site
  - Nové Zámky, Slovakiet, 940 01
    - Novartis Investigative Site
  - Nové Zámky, Slovakiet, 940 02
    - Novartis Investigative Site
  - Piešťany, Slovakiet, 921 01
    - Novartis Investigative Site
  - Považská Bystrica, Slovakiet, 017 01
    - Novartis Investigative Site
  - Prešov, Slovakiet, 080 01
    - Novartis Investigative Site
  - Rimavská Sobota, Slovakiet, 979 01
    - Novartis Investigative Site
  - Rožňava, Slovakiet, 048 01
    - Novartis Investigative Site
  - Svidník, Slovakiet, 089 01
    - Novartis Investigative Site
  - Žilina, Slovakiet, 010 01
    - Novartis Investigative Site
- Slovakia
  - Brezno, Slovakia, Slovakiet, 977 01
    - Novartis Investigative Site
  - Košice, Slovakia, Slovakiet, 040 01
    - Novartis Investigative Site
  - Trnava, Slovakia, Slovakiet, 917 02
    - Novartis Investigative Site
Slovenien
- - Ljubljana, Slovenien, 1000
    - Novartis Investigative Site
Spanien
- - A Coruña, Spanien, 15001
    - Novartis Investigative Site
  - Barcelona, Spanien, 08036
    - Novartis Investigative Site
  - Barcelona, Spanien, 08025
    - Novartis Investigative Site
  - Córdoba, Spanien, 14004
    - Novartis Investigative Site
  - Huelva, Spanien, 21080
    - Novartis Investigative Site
  - Madrid, Spanien, 28041
    - Novartis Investigative Site
  - Madrid, Spanien, 28040
    - Novartis Investigative Site
  - Málaga, Spanien, 29010
    - Novartis Investigative Site
  - Seville, Spanien, 41009
    - Novartis Investigative Site
  - Seville, Spanien, 41013
    - Novartis Investigative Site
  - Valencia, Spanien, 46010
    - Novartis Investigative Site
  - Zaragoza, Spanien, 50009
    - Novartis Investigative Site
- A Coruna
  - Santiago Compostela, A Coruna, Spanien, 15706
    - Novartis Investigative Site
- Andalusia
  - Seville, Andalusia, Spanien, 41014
    - Novartis Investigative Site
- Barcelona
  - Badalona, Barcelona, Spanien, 08916
    - Novartis Investigative Site
  - L'Hospitalet de Llobregat, Barcelona, Spanien, 08907
    - Novartis Investigative Site
- Cantabria
  - Santander, Cantabria, Spanien, 39008
    - Novartis Investigative Site
- Extremadura
  - Cáceres, Extremadura, Spanien, 10003
    - Novartis Investigative Site
- Tarragona
  - Reus, Tarragona, Spanien, 43201
    - Novartis Investigative Site
Sverige
- - Gothenburg, Sverige, 413 46
    - Novartis Investigative Site
  - Lund, Sverige, 222 21
    - Novartis Investigative Site
  - Stockholm, Sverige, 14186
    - Novartis Investigative Site
Sydafrika
- - Cape Town, Sydafrika, 6665
    - Novartis Investigative Site
- Gauteng
  - Soweto, Gauteng, Sydafrika, 2013
    - Novartis Investigative Site
- Western Cape
  - Cape Town, Western Cape, Sydafrika, 7500
    - Novartis Investigative Site
  - Cape Town, Western Cape, Sydafrika, 7925
    - Novartis Investigative Site
  - George, Western Cape, Sydafrika, 6529
    - Novartis Investigative Site
Sydkorea
- - Busan, Sydkorea, 49201
    - Novartis Investigative Site
  - Gwangju, Sydkorea, 61469
    - Novartis Investigative Site
  - Seoul, Sydkorea, 03181
    - Novartis Investigative Site
  - Seoul, Sydkorea, 06591
    - Novartis Investigative Site
- Dalseo gu
  - Daegu, Dalseo gu, Sydkorea, 42602
    - Novartis Investigative Site
- Gangwon-do
  - Wŏnju, Gangwon-do, Sydkorea, 26426
    - Novartis Investigative Site
- Gyeonggi-do
  - Bundang Gu, Gyeonggi-do, Sydkorea, 13620
    - Novartis Investigative Site
  - Suwon, Gyeonggi-do, Sydkorea, 16499
    - Novartis Investigative Site
- Korea
  - Incheon, Korea, Sydkorea, 405 760
    - Novartis Investigative Site
  - Seoul, Korea, Sydkorea, 08308
    - Novartis Investigative Site
  - Seoul, Korea, Sydkorea, 02841
    - Novartis Investigative Site
- Seoul
  - Seoul, Seoul, Sydkorea, 03080
    - Novartis Investigative Site
Taiwan
- - Hsinchu, Taiwan, 30069
    - Novartis Investigative Site
  - Kaohsiung City, Taiwan, 83301
    - Novartis Investigative Site
  - Kaohsiung City, Taiwan, 80756
    - Novartis Investigative Site
  - Keelung, Taiwan, 20401
    - Novartis Investigative Site
  - Tainan, Taiwan, 71004
    - Novartis Investigative Site
  - Taipei, Taiwan, 11217
    - Novartis Investigative Site
  - Taoyuan, Taiwan, 33305
    - Novartis Investigative Site
  - Yilan, Taiwan, 26058
    - Novartis Investigative Site
- Taiwan ROC
  - Taichung, Taiwan ROC, Taiwan, 40201
    - Novartis Investigative Site
Tjekkiet
- - Brandýs nad Labem, Tjekkiet, 250 01
    - Novartis Investigative Site
  - Brno, Tjekkiet, 625 00
    - Novartis Investigative Site
  - Brno, Tjekkiet, 602 00
    - Novartis Investigative Site
  - Broumov, Tjekkiet, 550 01
    - Novartis Investigative Site
  - CZE, Tjekkiet, 110 00
    - Novartis Investigative Site
  - Hlučín, Tjekkiet, 748 01
    - Novartis Investigative Site
  - Hodonín, Tjekkiet, 695 01
    - Novartis Investigative Site
  - Jihlava, Tjekkiet, 586 01
    - Novartis Investigative Site
  - Kolín, Tjekkiet, 280 20
    - Novartis Investigative Site
  - Liberec, Tjekkiet, 460 01
    - Novartis Investigative Site
  - Liberec, Tjekkiet, 460 05
    - Novartis Investigative Site
  - Mariánské Lázně, Tjekkiet, 353 01
    - Novartis Investigative Site
  - Most, Tjekkiet, 434 01
    - Novartis Investigative Site
  - Mělník, Tjekkiet, 276 01
    - Novartis Investigative Site
  - Olomouc, Tjekkiet, 779 00
    - Novartis Investigative Site
  - Ostrava, Tjekkiet, 700 30
    - Novartis Investigative Site
  - Ostrava, Tjekkiet, 710 00
    - Novartis Investigative Site
  - Pardubice, Tjekkiet, 532 03
    - Novartis Investigative Site
  - Polička, Tjekkiet, 57201
    - Novartis Investigative Site
  - Prague, Tjekkiet, 128 08
    - Novartis Investigative Site
  - Prague, Tjekkiet, 158 00
    - Novartis Investigative Site
  - Prague, Tjekkiet, 101 00
    - Novartis Investigative Site
  - Prague, Tjekkiet, 110 00
    - Novartis Investigative Site
  - Přerov, Tjekkiet, 751 52
    - Novartis Investigative Site
  - Slaný, Tjekkiet, 274 01
    - Novartis Investigative Site
  - Svitavy, Tjekkiet, 568 25
    - Novartis Investigative Site
  - Trutnov, Tjekkiet, 460 63
    - Novartis Investigative Site
  - Třebíč, Tjekkiet, 674 01
    - Novartis Investigative Site
  - Uherské Hradiště, Tjekkiet, 686 01
    - Novartis Investigative Site
  - Valašské Meziříčí, Tjekkiet, 75742
    - Novartis Investigative Site
  - Zlín, Tjekkiet, 760 01
    - Novartis Investigative Site
  - Český Krumlov, Tjekkiet, 381 01
    - Novartis Investigative Site
- Chlumec Nad Cidlinou
  - Chlumec nad Cidlinou, Chlumec Nad Cidlinou, Tjekkiet, 503 51
    - Novartis Investigative Site
- Czech Republic
  - Kroměříž, Czech Republic, Tjekkiet, 767 55
    - Novartis Investigative Site
  - Louny, Czech Republic, Tjekkiet, 440 01
    - Novartis Investigative Site
  - Ostrava, Czech Republic, Tjekkiet, 725 27
    - Novartis Investigative Site
  - Ústí nad Labem, Czech Republic, Tjekkiet, 400 01
    - Novartis Investigative Site
- Zabreh
  - Ostrava, Zabreh, Tjekkiet, 700 30
    - Novartis Investigative Site
Tyrkiet (Türkiye)
- - Izmir, Tyrkiet (Türkiye), 35100
    - Novartis Investigative Site
- Balcova
  - Izmir, Balcova, Tyrkiet (Türkiye), 35340
    - Novartis Investigative Site
- Bilkent-Cankaya
  - Ankara, Bilkent-Cankaya, Tyrkiet (Türkiye), 06800
    - Novartis Investigative Site
- Fatih
  - Istanbul, Fatih, Tyrkiet (Türkiye), 34098
    - Novartis Investigative Site
- Ilkadim
  - Samsun, Ilkadim, Tyrkiet (Türkiye), 55090
    - Novartis Investigative Site
- Kadikoy
  - Istanbul, Kadikoy, Tyrkiet (Türkiye), 34668
    - Novartis Investigative Site
- Odunpazari
  - Eskişehir, Odunpazari, Tyrkiet (Türkiye), 26040
    - Novartis Investigative Site
- Samsun
  - Samsun, Samsun, Tyrkiet (Türkiye), 55080
    - Novartis Investigative Site
- Yenisehir
  - Mersin, Yenisehir, Tyrkiet (Türkiye), 33110
    - Novartis Investigative Site
Tyskland
- - Aachen, Tyskland, 52074
    - Novartis Investigative Site
  - Bad Homburg, Tyskland, 61348
    - Novartis Investigative Site
  - Bad Krozingen, Tyskland, 79189
    - Novartis Investigative Site
  - Bad Oeynhausen, Tyskland, 32545
    - Novartis Investigative Site
  - Bamberg, Tyskland, 96049
    - Novartis Investigative Site
  - Berlin, Tyskland, 10367
    - Novartis Investigative Site
  - Berlin, Tyskland, 13353
    - Novartis Investigative Site
  - Berlin, Tyskland, 10787
    - Novartis Investigative Site
  - Berlin, Tyskland, 10789
    - Novartis Investigative Site
  - Berlin, Tyskland, 13347
    - Novartis Investigative Site
  - Berlin, Tyskland, 10559
    - Novartis Investigative Site
  - Bielefeld, Tyskland, 33604
    - Novartis Investigative Site
  - Chemnitz, Tyskland, 09122
    - Novartis Investigative Site
  - Dessau, Tyskland, 06846
    - Novartis Investigative Site
  - Dortmund, Tyskland, 44137
    - Novartis Investigative Site
  - Dresden, Tyskland, 01307
    - Novartis Investigative Site
  - Dresden, Tyskland, 01277
    - Novartis Investigative Site
  - Dresden, Tyskland, 01069
    - Novartis Investigative Site
  - Essen, Tyskland, 45277
    - Novartis Investigative Site
  - Essen, Tyskland, 45355
    - Novartis Investigative Site
  - Essen, Tyskland, 45359
    - Novartis Investigative Site
  - Gelnhausen, Tyskland, 63571
    - Novartis Investigative Site
  - Hamburg, Tyskland, 22041
    - Novartis Investigative Site
  - Hamburg, Tyskland, 22607
    - Novartis Investigative Site
  - Kassel, Tyskland, 34121
    - Novartis Investigative Site
  - Lüneburg, Tyskland, 21339
    - Novartis Investigative Site
  - Magdeburg, Tyskland, 39120
    - Novartis Investigative Site
  - Mannheim, Tyskland, 68165
    - Novartis Investigative Site
  - Meissen, Tyskland, 01662
    - Novartis Investigative Site
  - München, Tyskland, 80636
    - Novartis Investigative Site
  - Münster, Tyskland, 48149
    - Novartis Investigative Site
  - Potsdam, Tyskland, 14471
    - Novartis Investigative Site
  - Rüdersdorf, Tyskland, 15562
    - Novartis Investigative Site
  - Ulm, Tyskland, 89077
    - Novartis Investigative Site
  - Warendorf, Tyskland, 48231
    - Novartis Investigative Site
- Baden-Wurttemberg
  - Mannheim, Baden-Wurttemberg, Tyskland, 68305
    - Novartis Investigative Site
- Bavaria
  - Künzing, Bavaria, Tyskland, 94550
    - Novartis Investigative Site
  - Muehldorf Am Inn, Bavaria, Tyskland, 84453
    - Novartis Investigative Site
  - Munich, Bavaria, Tyskland, 81377
    - Novartis Investigative Site
  - Weiden in Der Oberpfalz, Bavaria, Tyskland, 92637
    - Novartis Investigative Site
- Hesse
  - Frankfurt am Main, Hesse, Tyskland, 60590
    - Novartis Investigative Site
  - Frankfurt am Main, Hesse, Tyskland, 60594
    - Novartis Investigative Site
- Lower Saxony
  - Hanover, Lower Saxony, Tyskland, 30159
    - Novartis Investigative Site
- North Rhine-Westphalia
  - Cologne, North Rhine-Westphalia, Tyskland, 50937
    - Novartis Investigative Site
  - Cologne, North Rhine-Westphalia, Tyskland, 50733
    - Novartis Investigative Site
  - Essen, North Rhine-Westphalia, Tyskland, 45355
    - Novartis Investigative Site
  - Löhne, North Rhine-Westphalia, Tyskland, 32584
    - Novartis Investigative Site
- Saarland
  - Saint Ingbert, Saarland, Tyskland, 66386
    - Novartis Investigative Site
- Saxony
  - Chemnitz, Saxony, Tyskland, 09113
    - Novartis Investigative Site
  - Dresden, Saxony, Tyskland, 01307
    - Novartis Investigative Site
  - Dresden, Saxony, Tyskland, 01099
    - Novartis Investigative Site
  - Leipzig, Saxony, Tyskland, 04103
    - Novartis Investigative Site
  - Leipzig, Saxony, Tyskland, 04107
    - Novartis Investigative Site
- Saxony-Anhalt
  - Wittenberg, Saxony-Anhalt, Tyskland, 06886
    - Novartis Investigative Site
- Thuringia
  - Jena, Thuringia, Tyskland, 07740
    - Novartis Investigative Site
Ungarn
- - Baja, Ungarn, 6500
    - Novartis Investigative Site
  - Budapest, Ungarn, H-1083
    - Novartis Investigative Site
  - Budapest, Ungarn, H-1097
    - Novartis Investigative Site
  - Budapest, Ungarn, 1204
    - Novartis Investigative Site
  - Budapest, Ungarn, H-1145
    - Novartis Investigative Site
  - Kistarcsa, Ungarn, 2143
    - Novartis Investigative Site
  - Makó, Ungarn, 6900
    - Novartis Investigative Site
  - Miskolc, Ungarn, 3526
    - Novartis Investigative Site
  - Nyíregyháza, Ungarn, 4400
    - Novartis Investigative Site
  - Szeged, Ungarn, 6725
    - Novartis Investigative Site
  - Székesfehérvár, Ungarn, H-8000
    - Novartis Investigative Site
- Baranya
  - Pécs, Baranya, Ungarn, 7623
    - Novartis Investigative Site
- Hajdu Bihar Megye
  - Debrecen, Hajdu Bihar Megye, Ungarn, 4032
    - Novartis Investigative Site
Østrig
- - Graz, Østrig, 8036
    - Novartis Investigative Site
  - Innsbruck, Østrig, 6020
    - Novartis Investigative Site
  - Linz, Østrig, 4021
    - Novartis Investigative Site
  - Salzburg, Østrig, 5020
    - Novartis Investigative Site
  - Vienna, Østrig, 1090
    - Novartis Investigative Site
  - Vienna, Østrig, 1210
    - Novartis Investigative Site

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år til 80 år (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Beskrivelse

Nøgleinklusionskriterier

Lp(a) ≥ 70 mg/dL ved screeningbesøget, målt på centrallaboratoriet
Myokardieinfarkt: ≥ 3 måneder fra screening og randomisering til ≤ 10 år før screeningsbesøget
Iskæmisk slagtilfælde: ≥ 3 måneder fra screening og randomisering til ≤ 10 år før screeningsbesøget
Klinisk signifikant symptomatisk perifer arteriesygdom

Nøgleudelukkelseskriterier

Ukontrolleret hypertension
Hjertesvigt New York Heart Association (NYHA) klasse IV
Historie om malignitet i ethvert organsystem
Anamnese med hæmoragisk slagtilfælde eller anden større blødning
Blodpladeantal ≤LLN
Aktiv leversygdom eller leverdysfunktion
Betydelig nyresygdom
Gravide eller ammende kvinder

Andre protokoldefinerede inklusions-/udelukkelseskriterier kan være gældende i slutningen.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Behandling
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Dobbelt

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Eksperimentel: TQJ230 TQJ230 80 mg injiceret månedligt indgivet subkutant	Medicin: TQJ230 TQJ230 80 mg injiceret månedligt indgivet subkutant
Placebo komparator: Placebo Månedlige subkutane injektioner.	Medicin: Placebo Placebo, der matcher TQJ230 forfyldt sprøjte, der skal injiceres subkutant Andre navne: Placebo til at matche TQJ230

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Tid til første forekomst af klinisk endepunktskomité bekræftet udvidede alvorlige kardiovaskulære hændelser hos patienter med forhøjet Lp(a) ≥ 70 mg/dL Tidsramme: cirka 4 år	Demonstrere pelacarsens (TQJ230) overlegenhed sammenlignet med placebo med hensyn til at reducere risikoen for udvidet MACE (kardiovaskulær død, ikke-fatal MI, ikke-dødelig slagtilfælde og akut koronar revaskularisering, der kræver hospitalsindlæggelse) i den samlede undersøgelsespopulation med etableret CVD og ( Lp(a) ≥ 70 mg/dL)	cirka 4 år
Tid til den første forekomst af klinisk effektudvalg bekræftede udvidede alvorlige kardiovaskulære hændelser i en population af patienter med forhøjet Lp(a) ≥ 90 mg/dL. Tidsramme: cirka 4 år	Demonstrere pelacarsens (TQJ230) overlegenhed sammenlignet med placebo med hensyn til at reducere risikoen for udvidet MACE (kardiovaskulær død, ikke-fatal MI, ikke-dødelig slagtilfælde og presserende koronar re-vaskularisering, der kræver hospitalsindlæggelse) i den samlede undersøgelsespopulation med etableret CVD og ( Lp(a) ≥ 90 mg/dL)	cirka 4 år

Sekundære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Tid til den første forekomst af den kliniske endepunktskomité bekræftet sammensat endepunkt af alvorlige uønskede kardiovaskulære hændelser (CV-død, ikke-dødelig MI og ikke-fatalt slagtilfælde) Tidsramme: cirka 4 år	Demonstrere pelacarsens (TQJ230) overlegenhed sammenlignet med placebo med hensyn til at reducere risikoen for MACE-sammensætningen af CV-død, ikke-dødelig MI og ikke-fatalt slagtilfælde.	cirka 4 år
Tid til den første forekomst af den kliniske endepunktskomité bekræftet sammensat endepunkt af koronar hjertesygdom: koronar hjertesygdom død, ikke-dødelig MI, presserende koronar re-vaskularisering, der kræver hospitalsindlæggelse Tidsramme: cirka 4 år	Demonstrere pelacarsens (TQJ230) overlegenhed sammenlignet med placebo med hensyn til at reducere risikoen for sammensatte udfald af koronar hjertesygdom (CHD): død på grund af CHD, ikke-fatal MI og akut koronar revaskularisering, der kræver hospitalsindlæggelse.	cirka 4 år
Tid til klinisk endepunktskomité bekræftede dødsfald af alle årsager Tidsramme: cirka 4 år	Evaluering af frekvensen af dødsfald af alle årsager foretaget af klinisk effektudvalg	cirka 4 år
Ændring i Lp(a) i log-skalaen fra baseline Tidsramme: Baseline, år 1	Demonstrere pelacarsens (TQJ230) overlegenhed sammenlignet med placebo med hensyn til at sænke Lp(a)-niveauet efter 1 år	Baseline, år 1

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Novartis Pharmaceuticals

Efterforskere

Studieleder: Novartis Pharmaceuticals, Novartis Pharmaceuticals

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

12. december 2019

Primær færdiggørelse (Anslået)

30. juni 2026

Studieafslutning (Anslået)

30. juni 2026

Datoer for studieregistrering

Først indsendt

16. juli 2019

Først indsendt, der opfyldte QC-kriterier

16. juli 2019

Først opslået (Faktiske)

17. juli 2019

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

6. maj 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

4. maj 2026

Sidst verificeret

1. maj 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

CTQJ230A12301 (Anden identifikator: Novartis)
2019-001076-11 (EudraCT nummer)

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

IPD-planbeskrivelse

Novartis er forpligtet til at dele med kvalificerede eksterne forskere, adgang til data på patientniveau og understøttende kliniske dokumenter fra kvalificerede undersøgelser. Disse anmodninger gennemgås og godkendes af et uafhængigt bedømmelsespanel på grundlag af videnskabelig fortjeneste. Alle data, der leveres, er anonymiserede for at respektere privatlivets fred for patienter, der har deltaget i forsøget i overensstemmelse med gældende love og regler.

Tilgængeligheden af denne forsøgsdata er i overensstemmelse med kriterierne og processen beskrevet på www.clinicalstudydatarequest.com.

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Studerer et amerikansk FDA-reguleret enhedsprodukt

Ingen

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Kliniske forsøg med Hjerte-kar-sygdomme og lipoprotein(a)

Changi General Hospital

Tilmelding efter invitation

Implementering af forskning på LILAC -metoden til at uddanne styring af forhøjet lipoprotein (A). (LILAC-UNI)

Lipoprotein(a) | Lipoprotein(a), Hyper-Lp(a)-Emia

Singapore, Australien, Malaysia
Ionis Pharmaceuticals, Inc.

Afsluttet

Sikkerhed, tolerabilitet, farmakokinetik og farmakodynamik af ISIS-APO(a)Rx hos deltagere med højt lipoprotein(a)

Forhøjet lipoprotein(a)

Holland, Det Forenede Kongerige, Danmark, Tyskland, Canada
Merck Sharp & Dohme LLC

Ikke rekrutterer endnu

A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004)

Lipoprotein(a)
Ionis Pharmaceuticals, Inc.
Akcea Therapeutics

Afsluttet

Sikkerhed, tolerabilitet, farmakokinetik og farmakodynamik af IONIS APO(a)-LRx hos raske frivillige med forhøjet lipoprotein(a)

Forhøjet lipoprotein(a)

Canada
Polish Mother Memorial Hospital Research Institute

Rekruttering

Forekomsten af Hyper-Lp(a)-Emia i PMMHRI-Lp(a)-registret

Lipoprotein(a), Hyper-Lp(a)-Emia

Polen
Charite University, Berlin, Germany

Ukendt

Evaluering af effekten af NICOtinsyre (Niacin) på forhøjede niveauer af lipoprotein(a) (NICOLa-undersøgelse) (NICOLa)

Forhøjede niveauer af lipoprotein(a).

Tyskland
Akcea Therapeutics

Afsluttet

Lægemiddel-lægemiddelinteraktionsundersøgelse for at evaluere effekten af ISIS 681257 på warfarin

Hjerte-kar-sygdomme | Forhøjet lipoprotein(a)

Canada
Akcea Therapeutics

Afsluttet

Lægemiddel-lægemiddelinteraktionsundersøgelse for at evaluere effekten af ISIS 681257 på Clopidogrel

Hjerte-kar-sygdomme | Forhøjet lipoprotein(a)

Canada
Eli Lilly and Company

Ikke rekrutterer endnu

A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk (ACCLAIM-CTA)

Hjerte-kar-sygdomme | Åreforkalkning | Lipoprotein(a)

Spanien, Forenede Stater, Holland, Det Forenede Kongerige, Ungarn, Tjekkiet, Australien
Silence Therapeutics plc

Afsluttet

Evaluer SLN360 hos deltagere med forhøjet lipoprotein(a) med høj risiko for hændelser af aterosklerotiske kardiovaskulære sygdomme

Hjerte-kar-sygdomme | Åreforkalkning | Lipoprotein(a)

Danmark, Holland, Australien, Det Forenede Kongerige, Sydafrika, Tjekkiet, Slovakiet

Kliniske forsøg med TQJ230

Novartis Pharmaceuticals

Rekruttering

En Open Label Extension (OLE)-undersøgelse (efter afslutning af CTQJ230A12301) til evaluering af langsigtet sikkerhed og tolerabilitet af Pelacarsen (TQJ230)

Hjerte-kar-sygdomme og lipoprotein(a)

Forenede Stater, Kina, Italien, Spanien, Canada, Danmark, Frankrig, Schweiz, Taiwan, Østrig, Israel, Rumænien, Grækenland, Tyskland, Australien, Hong Kong, Argentina, Bulgarien, Indien, Det Forenede Kongerige, Polen, Brasilien, Tjekkiet og mere
Novartis Pharmaceuticals

Rekruttering

Pelacarsen open-label roll-over-udvidelsesprogram '

Aterosklerotisk kardiovaskulær sygdom

Forenede Stater, Puerto Rico
Novartis Pharmaceuticals

Aktiv, ikke rekrutterende

En Open Label Extension (OLE) undersøgelse for at evaluere langsigtet sikkerhed og tolerabilitet af Pelacarsen (TQJ230) (OLE)

Hyperlipoproteinæmi (a)

Tyskland
Novartis Pharmaceuticals

Rekruttering

Et multicenterforsøg, der vurderer virkningen af lipoprotein(a)-sænkning med Pelacarsen (TQJ230) på udviklingen af forkalkning af aortaklapstenose

Aortastenose

Forenede Stater, Italien, Spanien, Østrig, Canada, Frankrig, Tyskland, Schweiz, Det Forenede Kongerige, Israel, Danmark, Portugal, Belgien, Tjekkiet, Holland
University Medical Centre Ljubljana

Trukket tilbage

Pelacarsens indflydelse på patienter efter myokardieinfarkt med høje Lp(a)-værdier (PEMILA)

Betændelse | Akut koronarsyndrom | Lipoproteinæmi | Genetiske polymorfier

Slovenien
Novartis Pharmaceuticals

Afsluttet

Et multicenterforsøg, der vurderer virkningen af Lipoprotein(a)-sænkning med Pelacarsen (TQJ230) på frekvensen af ugentlige Lipoprotein-aferesesessioner hos patienter med hyperlipoproteinæmi(a) og etableret kardiovaskulær sygdom i Tyskland

Hyperlipoproteinæmi(a)

Tyskland
Novartis Pharmaceuticals

Ledig

Administrerede adgangsprogrammer til TQJ230, Pelacarsen

Aterosklerotisk hjerte -kar -sygdom, ASCVD
Novartis Pharmaceuticals

Afsluttet

Undersøgelse for at vurdere farmakokinetikken af Pelacarsen (TQJ230) hos deltagere med let nedsat leverfunktion sammenlignet med matchede raske deltagere

Nedsat leverfunktion

Forenede Stater
Novartis Pharmaceuticals

Afsluttet

Lp(a)-sænkende undersøgelse af Pelacarsen (TQJ230) i amerikanske sorte/afrikanske amerikanske og latinamerikanske deltagere med forhøjet Lp(a) og etableret ASCVD

Forhøjet Lp(a) og etableret aterosklerotisk kardiovaskulær sygdom

Forenede Stater, Puerto Rico
Ionis Pharmaceuticals, Inc.

Afsluttet

En undersøgelse til vurdering af sikkerhed, tolerabilitet, farmakokinetik og farmakodynamik af Pelacarsen (ISIS 681257) hos raske japanske deltagere

Sunde deltagere

Forenede Stater

Vurdering af virkningen af ​​Lipoprotein (a) Sænkning med Pelacarsen (TQJ230) på større kardiovaskulære hændelser hos patienter med CVD (Lp(a)HORIZON)

Et randomiseret dobbeltblindt, placebokontrolleret, multicenterforsøg, der vurderer virkningen af ​​lipoprotein (a) sænkning med Pelacarsen (TQJ230) på større kardiovaskulære hændelser hos patienter med etableret kardiovaskulær sygdom

Studieoversigt

Status

Betingelser

Intervention / Behandling

Undersøgelsestype

Tilmelding (Faktiske)

Fase

Udvidet adgang

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal våben

Våben og indgreb

Deltagergruppe / Arm

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Efterforskere

Publikationer og nyttige links

Generelle publikationer

Datoer for undersøgelser

Studer store datoer

Studiestart (Faktiske)

Primær færdiggørelse (Anslået)

Studieafslutning (Anslået)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Faktiske)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

IPD-planbeskrivelse

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Studerer et amerikansk FDA-reguleret enhedsprodukt

Kliniske forsøg med Hjerte-kar-sygdomme og lipoprotein(a)

Kliniske forsøg med TQJ230

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Portugal

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer

Vurdering af virkningen af Lipoprotein (a) Sænkning med Pelacarsen (TQJ230) på større kardiovaskulære hændelser hos patienter med CVD (Lp(a)HORIZON)

Et randomiseret dobbeltblindt, placebokontrolleret, multicenterforsøg, der vurderer virkningen af lipoprotein (a) sænkning med Pelacarsen (TQJ230) på større kardiovaskulære hændelser hos patienter med etableret kardiovaskulær sygdom