Association of Egg and Dietary Cholesterol Consumption With Mortality and Diseases

March 12, 2024 updated by: Jingjing Jiao, Zhejiang University

Association of Egg and Dietary Cholesterol Consumption With Mortality and Metabolic Syndrome

To assess the associations between egg and dietary cholesterol consumption with mortality and metabolic syndrome (MetS).

Study Overview

Status

Completed

Conditions

Detailed Description

Substitution models, sensitivity analyses, subgroup analyses and multiple linear regression analyses will be conducted to specifically estimate the hazard ratios and 95% confidence intervals of mortality and MetS associated with egg and cholesterol consumption.

Study Type

Observational

Enrollment (Actual)

33453

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

N/A

Sampling Method

Probability Sample

Study Population

The CHNS is a nationwide cohort survey in China, which was established as a joint project of the University of North Carolina at Chapel and the China Center for Disease Control and Prevention (CCDC).This national-wide survey adopted a novel measure from multiple dimensions, which helped to understand how the long-term social and economic changes affected nutrition and health-related outcomes of Chinese. Until now, 10 rounds of survey (1989, 1991, 1993, 1997, 2000, 2004, 2006, 2009, 2011 and 2015) have been conducted.

Description

Inclusion Criteria:

  • participants aged ≥20 y

Exclusion Criteria:

  • missing creatinine, age, cannot be linked to socio-demographic data; aged less than 20; without complete dietary data .

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
mortality
Time Frame: participants were followed up from 1991 to 2015
mortality
participants were followed up from 1991 to 2015

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
metabolic syndrome
Time Frame: The blood samples were collected in 2009 for the first time.
MetS was defined according to the updated National Cholesterol Education Program Adult Treatment Panel III (NCEP: ATP III) criteria for Asian-Americans.
The blood samples were collected in 2009 for the first time.

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Zhejiang University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 1991

Primary Completion (Actual)

January 1, 2015

Study Completion (Actual)

December 31, 2015

Study Registration Dates

First Submitted

September 24, 2019

First Submitted That Met QC Criteria

September 24, 2019

First Posted (Actual)

September 26, 2019

Study Record Updates

Last Update Posted (Actual)

March 15, 2024

Last Update Submitted That Met QC Criteria

March 12, 2024

Last Verified

March 1, 2024

More Information

Terms related to this study

Other Study ID Numbers

  • Cohort_egg_mortality

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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