Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease (VICTORION-2P)

A Randomized, Double-blind, Placebo-controlled, Multicenter Trial, Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Participants With Established Cardiovascular Disease (VICTORION-2 PREVENT)

Study CKJX839B12302 is a pivotal Phase III trial to evaluate the benefits of inclisiran on major adverse cardiovascular (MACE) events in participants with established cardiovascular disease (CVD).

Study Overview

• Status: Active, not recruiting
• Conditions: Atherosclerotic Cardiovascular Disease
• Intervention / Treatment: Drug: Inclisiran sodium 300 mg; Drug: Placebo

Detailed Description

Purpose of this study is to test the hypothesis that treatment with inclisiran sodium 300 mg s.c. administered on Day 1, Month 3 (Day 90), and every 6 months thereafter taken in addition to well-tolerated high-intensity statin therapy in participants with established ASCVD will significantly reduce the risk of 3-Point-Major Adverse Cardiovascular Events (3P-MACE) defined as a composite of CV death, non-fatal myocardial infarction (MI) and non-fatal ischemic stroke. This will be compared to placebo in adjunct to well-tolerated high-intensity statin therapy.

• Study Type: Interventional
• Enrollment (Actual): 17004
• Phase: Phase 3

Contacts and Locations

Study Locations

• Argentina
  • Buenos Aires, Argentina, C1012AAR
    • Novartis Investigative Site
  • Buenos Aires, Argentina, C1428DCO
    • Novartis Investigative Site
  • Buenos Aires, Argentina, C1425AGP
    • Novartis Investigative Site
  • Caba, Argentina, C1426
    • Novartis Investigative Site
  • Corrientes, Argentina, W3400CDS
    • Novartis Investigative Site
  • Córdoba, Argentina, X5002
    • Novartis Investigative Site
  • Mendoza, Argentina, 5500
    • Novartis Investigative Site
  • Santa Fe, Argentina, S3000EOZ
    • Novartis Investigative Site
  • Buenos Aires
    • CABA, Buenos Aires, Argentina, C1221ADC
      • Novartis Investigative Site
    • CABA, Buenos Aires, Argentina, C1405BCH
      • Novartis Investigative Site
    • CABA, Buenos Aires, Argentina, C1056ABI
      • Novartis Investigative Site
    • CABA, Buenos Aires, Argentina, 1280
      • Novartis Investigative Site
    • CABA, Buenos Aires, Argentina, 1426
      • Novartis Investigative Site
    • CABA, Buenos Aires, Argentina, C1187AAN
      • Novartis Investigative Site
    • Caba, Buenos Aires, Argentina, C1119ACN
      • Novartis Investigative Site
    • Mar del Plata, Buenos Aires, Argentina, 7600
      • Novartis Investigative Site
    • Quilmes, Buenos Aires, Argentina, B1878GEG
      • Novartis Investigative Site
    • Ramos Mejía, Buenos Aires, Argentina, B1704ETD
      • Novartis Investigative Site
    • San Martín, Buenos Aires, Argentina, B1650CSQ
      • Novartis Investigative Site
  • Córdoba Province
    • Córdoba, Córdoba Province, Argentina, 5000
      • Novartis Investigative Site
  • Formosa Province
    • Formosa, Formosa Province, Argentina, P3600
      • Novartis Investigative Site
  • Misiones Province
    • Posadas, Misiones Province, Argentina, N3300
      • Novartis Investigative Site
  • Salta Province
    • Salta, Salta Province, Argentina, A4406BPF
      • Novartis Investigative Site
  • San Miguel de Tucuman
    • San Miguel de Tucumán, San Miguel de Tucuman, Argentina, T4000ICL
      • Novartis Investigative Site
  • Santa Fe Province
    • Rosario, Santa Fe Province, Argentina, 2000
      • Novartis Investigative Site
    • Rosario, Santa Fe Province, Argentina, S2000AII
      • Novartis Investigative Site
    • Rosario, Santa Fe Province, Argentina, S200CVD
      • Novartis Investigative Site
    • Santa Fe, Santa Fe Province, Argentina, S3000FWO
      • Novartis Investigative Site
  • Tucumán Province
    • San Miguel Tucuman, Tucumán Province, Argentina, T4000IFL
      • Novartis Investigative Site
• Australia
  • Liverpool, Australia, 2170
    • Novartis Investigative Site
  • New South Wales
    • Botany, New South Wales, Australia, 2019
      • Novartis Investigative Site
    • New Lambton Heights, New South Wales, Australia, 2305
      • Novartis Investigative Site
  • Queensland
    • Auchenflower, Queensland, Australia, 4066
      • Novartis Investigative Site
    • Milton, Queensland, Australia, 4064
      • Novartis Investigative Site
    • Woolloongabba, Queensland, Australia, 4102
      • Novartis Investigative Site
  • South Australia
    • Adelaide, South Australia, Australia, 5000
      • Novartis Investigative Site
    • Bedford Park, South Australia, Australia, 5041
      • Novartis Investigative Site
    • Leabrook, South Australia, Australia, 5068
      • Novartis Investigative Site
    • Woodville South, South Australia, Australia, 5011
      • Novartis Investigative Site
  • Victoria
    • Clayton, Victoria, Australia, 3168
      • Novartis Investigative Site
    • Geelong, Victoria, Australia, 3220
      • Novartis Investigative Site
    • Malvern East, Victoria, Australia, 3145
      • Novartis Investigative Site
    • Richmond, Victoria, Australia, 3121
      • Novartis Investigative Site
  • Western Australia
    • Joondalup, Western Australia, Australia, 6027
      • Novartis Investigative Site
    • Nedlands, Western Australia, Australia, 6009
      • Novartis Investigative Site
• Austria
  • Braunau am Inn, Austria, 5280
    • Novartis Investigative Site
  • Graz, Austria, 8036
    • Novartis Investigative Site
• Belgium
  • Antwerp, Belgium, 2020
    • Novartis Investigative Site
  • Brasschaat, Belgium, 2930
    • Novartis Investigative Site
  • Bruges, Belgium, 8000
    • Novartis Investigative Site
  • Brussels, Belgium, 1020
    • Novartis Investigative Site
  • Charleroi, Belgium, 6000
    • Novartis Investigative Site
  • Edegem, Belgium, 2650
    • Novartis Investigative Site
  • Ghent, Belgium, 9000
    • Novartis Investigative Site
  • La Louvière, Belgium, 7100
    • Novartis Investigative Site
  • Ronse, Belgium, 9600
    • Novartis Investigative Site
  • Limburg
    • Genk, Limburg, Belgium, 3600
      • Novartis Investigative Site
  • Namur
    • Yvoir, Namur, Belgium, 5530
      • Novartis Investigative Site
  • West-Vlaanderen
    • Kortrijk, West-Vlaanderen, Belgium, 8500
      • Novartis Investigative Site
    • Roeselare, West-Vlaanderen, Belgium, 8800
      • Novartis Investigative Site
• Brazil
  • Campinas, Brazil, 13092-133
    • Novartis Investigative Site
  • Rio de Janeiro, Brazil, 20241-180
    • Novartis Investigative Site
  • São Paulo, Brazil, 04026-090
    • Novartis Investigative Site
  • Alagoas
    • Maceió, Alagoas, Brazil, 57051-160
      • Novartis Investigative Site
  • Espírito Santo
    • Vitória, Espírito Santo, Brazil, 29055-450
      • Novartis Investigative Site
  • Estado de Bahia
    • Salvador, Estado de Bahia, Brazil, 40170-130
      • Novartis Investigative Site
  • Federal District
    • Brasília, Federal District, Brazil, 71625-009
      • Novartis Investigative Site
    • Brasília, Federal District, Brazil, 70390-700
      • Novartis Investigative Site
  • Minas Gerais
    • Belo Horizonte, Minas Gerais, Brazil, 30220-330
      • Novartis Investigative Site
    • Uberlândia, Minas Gerais, Brazil, 38400 500
      • Novartis Investigative Site
  • Paraná
    • Curitiba, Paraná, Brazil, 80730-150
      • Novartis Investigative Site
  • Rio Grande do Sul
    • Canoas, Rio Grande do Sul, Brazil, 92425-900
      • Novartis Investigative Site
    • Pelotas, Rio Grande do Sul, Brazil, 96015-290
      • Novartis Investigative Site
    • Porto Alegre, Rio Grande do Sul, Brazil, 90880-480
      • Novartis Investigative Site
    • Porto Alegre, Rio Grande do Sul, Brazil, 90560-032
      • Novartis Investigative Site
    • Porto Alegre, Rio Grande do Sul, Brazil, 90160-093
      • Novartis Investigative Site
  • Santa Catarina
    • Blumenau, Santa Catarina, Brazil, 89020-430
      • Novartis Investigative Site
  • Sergipe
    • Aracaju, Sergipe, Brazil, 49055-530
      • Novartis Investigative Site
  • São Paulo
    • Campinas, São Paulo, Brazil, 13060 080
      • Novartis Investigative Site
    • Ribeirão Preto, São Paulo, Brazil, 14048-900
      • Novartis Investigative Site
    • Santo André, São Paulo, Brazil, 09030-010
      • Novartis Investigative Site
    • Santo André, São Paulo, Brazil, 09060-870
      • Novartis Investigative Site
    • Santo André, São Paulo, Brazil, 09090-790
      • Novartis Investigative Site
    • Sao Jose Rio Preto, São Paulo, Brazil, 15015-750
      • Novartis Investigative Site
    • Sao Jose Rio Preto, São Paulo, Brazil, 15090-000
      • Novartis Investigative Site
    • São Paulo, São Paulo, Brazil, 01323-903
      • Novartis Investigative Site
    • São Paulo, São Paulo, Brazil, 04005-003
      • Novartis Investigative Site
    • São Paulo, São Paulo, Brazil, 04266 010
      • Novartis Investigative Site
    • São Paulo, São Paulo, Brazil, 05403 000
      • Novartis Investigative Site
    • São Paulo, São Paulo, Brazil, 09715 090
      • Novartis Investigative Site
• Bulgaria
  • Burgas, Bulgaria, 8000
    • Novartis Investigative Site
  • Haskovo, Bulgaria, 6304
    • Novartis Investigative Site
  • Kyustendil, Bulgaria, 2500
    • Novartis Investigative Site
  • Montana, Bulgaria, 3400
    • Novartis Investigative Site
  • Pernik, Bulgaria, 2300
    • Novartis Investigative Site
  • Pleven, Bulgaria, 5800
    • Novartis Investigative Site
  • Plovdiv, Bulgaria, 4000
    • Novartis Investigative Site
  • Rousse, Bulgaria, 7000
    • Novartis Investigative Site
  • Sliven, Bulgaria, 8800
    • Novartis Investigative Site
  • Sofia, Bulgaria, 1527
    • Novartis Investigative Site
  • Sofia, Bulgaria, 1113
    • Novartis Investigative Site
  • Sofia, Bulgaria, 1431
    • Novartis Investigative Site
  • Sofia, Bulgaria, 1407
    • Novartis Investigative Site
  • Sofia, Bulgaria, 1750
    • Novartis Investigative Site
  • Sofia, Bulgaria, 1510
    • Novartis Investigative Site
  • Sofia, Bulgaria, 1582
    • Novartis Investigative Site
  • Stamboliyski, Bulgaria, 4210
    • Novartis Investigative Site
  • Stara Zagora, Bulgaria, 6000
    • Novartis Investigative Site
  • Stara Zagora, Bulgaria, 6003
    • Novartis Investigative Site
  • Veliko Tarnovo, Bulgaria, 5000
    • Novartis Investigative Site
  • Blagoevgrad
    • Sandanski, Blagoevgrad, Bulgaria, 2850
      • Novartis Investigative Site
  • Bulgaria
    • Rousse, Bulgaria, Bulgaria, 7012
      • Novartis Investigative Site
    • Sofia, Bulgaria, Bulgaria, 1202
      • Novartis Investigative Site
    • Stara Zagora, Bulgaria, Bulgaria, 6000
      • Novartis Investigative Site
  • Burgas
    • Burgas, Burgas, Bulgaria, 8000
      • Novartis Investigative Site
  • Sofia-Grad
    • Sofia, Sofia-Grad, Bulgaria, 1040
      • Novartis Investigative Site
• Canada
  • Alberta
    • Calgary, Alberta, Canada, T2N 4N1
      • Novartis Investigative Site
    • Edmonton, Alberta, Canada, T5H 4B9
      • Novartis Investigative Site
    • Edmonton, Alberta, Canada, T6K 4C1
      • Novartis Investigative Site
  • British Columbia
    • North Vancouver, British Columbia, Canada, V7M 2H4
      • Novartis Investigative Site
    • Vancouver, British Columbia, Canada, V6Z 1Y6
      • Novartis Investigative Site
    • Vancouver, British Columbia, Canada, V5Z 1M9
      • Novartis Investigative Site
    • Victoria, British Columbia, Canada, V8R4R2
      • Novartis Investigative Site
    • Victoria, British Columbia, Canada, V8T 5G4
      • Novartis Investigative Site
    • Victoria, British Columbia, Canada, V8V 4A1
      • Novartis Investigative Site
  • Manitoba
    • Winnipeg, Manitoba, Canada, R3C 0N2
      • Novartis Investigative Site
    • Winnipeg, Manitoba, Canada, R3L 1Z5
      • Novartis Investigative Site
  • New Brunswick
    • Moncton, New Brunswick, Canada, E1G 1A7
      • Novartis Investigative Site
  • Nova Scotia
    • Halifax, Nova Scotia, Canada, B3H 2Y9
      • Novartis Investigative Site
    • Sydney, Nova Scotia, Canada, B1P 1P3
      • Novartis Investigative Site
  • Ontario
    • Cambridge, Ontario, Canada, N1R 7R1
      • Novartis Investigative Site
    • Guelph, Ontario, Canada, N1H 1B1
      • Novartis Investigative Site
    • Newmarket, Ontario, Canada, L3Y 2P6
      • Novartis Investigative Site
    • Oakville, Ontario, Canada, L6K 3W7
      • Novartis Investigative Site
    • Peterborough, Ontario, Canada, K9J 0B2
      • Novartis Investigative Site
    • Sarnia, Ontario, Canada, N7T 4X3
      • Novartis Investigative Site
    • Scarborough Village, Ontario, Canada, M1B 4Z8
      • Novartis Investigative Site
    • Scarborough Village, Ontario, Canada, M1B 5N1
      • Novartis Investigative Site
    • Stoufville, Ontario, Canada, L4A 1H2
      • Novartis Investigative Site
  • Quebec
    • Greenfield Park, Quebec, Canada, J4V 2G8
      • Novartis Investigative Site
    • Montreal, Quebec, Canada, H2X 1R9
      • Novartis Investigative Site
    • Montreal, Quebec, Canada, H3M 1L3
      • Novartis Investigative Site
    • Montreal, Quebec, Canada, H4N 2W2
      • Novartis Investigative Site
    • Québec, Quebec, Canada, G1W 4R4
      • Novartis Investigative Site
    • Québec, Quebec, Canada, G2J 0C4
      • Novartis Investigative Site
    • Québec, Quebec, Canada, G1V 4G5
      • Novartis Investigative Site
    • Saint-Jérôme, Quebec, Canada, J7Z 5T3
      • Novartis Investigative Site
    • Sainte-Foy, Quebec, Canada, G1V 4G2
      • Novartis Investigative Site
    • Terrebonne, Quebec, Canada, J6V 2H2
      • Novartis Investigative Site
    • Trois-Rivières, Quebec, Canada, G8Z 3R9
      • Novartis Investigative Site
• Chile
  • Santiago, Chile, 8380456
    • Novartis Investigative Site
  • Araucania
    • Temuco, Araucania, Chile, 4781156
      • Novartis Investigative Site
    • Victoria, Araucania, Chile, 4720097
      • Novartis Investigative Site
  • Coquimbo Region
    • La Serena, Coquimbo Region, Chile, 1720430
      • Novartis Investigative Site
  • Los Lagos Region
    • Osorno, Los Lagos Region, Chile, 5290000
      • Novartis Investigative Site
  • Santiago Metropolitan
    • Santiago, Santiago Metropolitan, Chile, 8331143
      • Novartis Investigative Site
    • Santiago, Santiago Metropolitan, Chile, 7500710
      • Novartis Investigative Site
    • Santiago, Santiago Metropolitan, Chile, 8380465
      • Novartis Investigative Site
  • Valparaiso
    • Viña del Mar, Valparaiso, Chile, 2520997
      • Novartis Investigative Site
• China
  • Beijing, China, 100029
    • Novartis Investigative Site
  • Beijing, China, 100034
    • Novartis Investigative Site
  • Beijing, China, 100050
    • Novartis Investigative Site
  • Beijing, China, 100191
    • Novartis Investigative Site
  • Beijing, China, 100039
    • Novartis Investigative Site
  • Chongqing, China, 400016
    • Novartis Investigative Site
  • Guangzhou, China, 510280
    • Novartis Investigative Site
  • Jinan, China, 250012
    • Novartis Investigative Site
  • Shanghai, China, 200080
    • Novartis Investigative Site
  • Shanghai, China, 200032
    • Novartis Investigative Site
  • Shanghai, China, 200025
    • Novartis Investigative Site
  • Shanghai, China, 200040
    • Novartis Investigative Site
  • Tianjin, China, 300140
    • Novartis Investigative Site
  • Xiamen, China, 361004
    • Novartis Investigative Site
  • Beijing Municipality
    • Beijing, Beijing Municipality, China, 100013
      • Novartis Investigative Site
  • Guangdong
    • Foshan, Guangdong, China, 528000
      • Novartis Investigative Site
    • Guangzhou, Guangdong, China, 510080
      • Novartis Investigative Site
    • Guangzhou, Guangdong, China, 510030
      • Novartis Investigative Site
    • Guangzhou, Guangdong, China, 510000
      • Novartis Investigative Site
    • Guangzhou, Guangdong, China, 510515
      • Novartis Investigative Site
  • Guangxi
    • Nanning, Guangxi, China, 530022
      • Novartis Investigative Site
  • Heilongjiang
    • Harbin, Heilongjiang, China, 150000
      • Novartis Investigative Site
  • Hubei
    • Jingzhou, Hubei, China, 434020
      • Novartis Investigative Site
    • Wuhan, Hubei, China, 430060
      • Novartis Investigative Site
    • Wuhan, Hubei, China, 430022
      • Novartis Investigative Site
    • Wuhan, Hubei, China, 430014
      • Novartis Investigative Site
  • Hunan
    • Changsha, Hunan, China, 410011
      • Novartis Investigative Site
    • Changsha, Hunan, China, 410003
      • Novartis Investigative Site
  • Inner Mongolia
    • Hohhot, Inner Mongolia, China, 010017
      • Novartis Investigative Site
  • Jiangsu
    • Changzhou, Jiangsu, China, 213004
      • Novartis Investigative Site
    • Jiangyin, Jiangsu, China, 214499
      • Novartis Investigative Site
    • Nanjing, Jiangsu, China, 210008
      • Novartis Investigative Site
    • Nanjing, Jiangsu, China, 210009
      • Novartis Investigative Site
    • Nanjing, Jiangsu, China, 211166
      • Novartis Investigative Site
    • Suzhou, Jiangsu, China, 215004
      • Novartis Investigative Site
    • Xuzhou, Jiangsu, China, 221003
      • Novartis Investigative Site
  • Jiangxi
    • Nanchang, Jiangxi, China, 330006
      • Novartis Investigative Site
    • Pingxiang, Jiangxi, China, 337000
      • Novartis Investigative Site
  • Jilin
    • Changchun, Jilin, China, 130000
      • Novartis Investigative Site
  • Liaoning
    • Dalian, Liaoning, China, 116011
      • Novartis Investigative Site
    • Shenyang, Liaoning, China, 110004
      • Novartis Investigative Site
  • Shandong
    • Jinan, Shandong, China, 250013
      • Novartis Investigative Site
  • Shanxi
    • Taiyuan, Shanxi, China, 030002
      • Novartis Investigative Site
    • Xian, Shanxi, China, 710061
      • Novartis Investigative Site
  • Sichuan
    • Chengdu, Sichuan, China, 610041
      • Novartis Investigative Site
  • Tianjin Municipality
    • Tianjin, Tianjin Municipality, China, 300121
      • Novartis Investigative Site
  • Xinjiang
    • Ürümqi, Xinjiang, China, 830001
      • Novartis Investigative Site
    • Ürümqi, Xinjiang, China, 830054
      • Novartis Investigative Site
  • Zhejiang
    • Hangzhou, Zhejiang, China, 310016
      • Novartis Investigative Site
    • Lishui, Zhejiang, China, 323000
      • Novartis Investigative Site
    • Taizhou, Zhejiang, China, 318000
      • Novartis Investigative Site
• Colombia
  • Bogotá, Colombia, 110221
    • Novartis Investigative Site
  • Floridablanca, Colombia, 681017
    • Novartis Investigative Site
  • Antioquia
    • Medellín, Antioquia, Colombia, 050021
      • Novartis Investigative Site
    • Medellín, Antioquia, Colombia, 050036
      • Novartis Investigative Site
  • Atlántico
    • Barranquilla, Atlántico, Colombia, 080002
      • Novartis Investigative Site
    • Barranquilla, Atlántico, Colombia, 080020
      • Novartis Investigative Site
  • Caldas Department
    • Manizales, Caldas Department, Colombia, 1700
      • Novartis Investigative Site
  • Colombia
    • Barranquilla, Colombia, Colombia, 080020
      • Novartis Investigative Site
    • Cali, Colombia, Colombia, 760024
      • Novartis Investigative Site
  • Departamento de Bolívar
    • Cartagena, Departamento de Bolívar, Colombia, 130001
      • Novartis Investigative Site
  • Risaralda Department
    • Pereira, Risaralda Department, Colombia, 660003
      • Novartis Investigative Site
  • Valle del Cauca Department
    • Cali, Valle del Cauca Department, Colombia, 760001
      • Novartis Investigative Site
    • Cali, Valle del Cauca Department, Colombia, 760032
      • Novartis Investigative Site
• Croatia
  • Opatija, Croatia, 51410
    • Novartis Investigative Site
  • Osijek, Croatia, 31000
    • Novartis Investigative Site
  • Rijeka, Croatia, 51000
    • Novartis Investigative Site
  • Split, Croatia, 21000
    • Novartis Investigative Site
  • Zagreb, Croatia, 10000
    • Novartis Investigative Site
  • Čakovec, Croatia, 40000
    • Novartis Investigative Site
  • Croatia
    • Krapinske Toplice, Croatia, Croatia, 49 217
      • Novartis Investigative Site
    • Slavonski Brod, Croatia, Croatia, 35000
      • Novartis Investigative Site
    • Zagreb, Croatia, Croatia, 10000
      • Novartis Investigative Site
• Czechia
  • Bedihošť, Czechia, 798 21
    • Novartis Investigative Site
  • Brno, Czechia, 625 00
    • Novartis Investigative Site
  • Brno, Czechia, 638 00
    • Novartis Investigative Site
  • Brno, Czechia, 602 00
    • Novartis Investigative Site
  • Hodonín, Czechia, 695 01
    • Novartis Investigative Site
  • Hradec Králové, Czechia, 500 05
    • Novartis Investigative Site
  • Jihlava, Czechia, 586 01
    • Novartis Investigative Site
  • Mariánské Lázně, Czechia, 353 01
    • Novartis Investigative Site
  • Náchod, Czechia, 547 01
    • Novartis Investigative Site
  • Ostrava, Czechia, 700 30
    • Novartis Investigative Site
  • Ostrava, Czechia, 728 80
    • Novartis Investigative Site
  • Ostrava, Czechia, 710 00
    • Novartis Investigative Site
  • Pardubice, Czechia, 532 03
    • Novartis Investigative Site
  • Polička, Czechia, 57201
    • Novartis Investigative Site
  • Prague, Czechia, 100 34
    • Novartis Investigative Site
  • Prague, Czechia, 120 00
    • Novartis Investigative Site
  • Prague, Czechia, 158 00
    • Novartis Investigative Site
  • Přerov, Czechia, 751 52
    • Novartis Investigative Site
  • Příbram, Czechia, 261 01
    • Novartis Investigative Site
  • Slaný, Czechia, 274 01
    • Novartis Investigative Site
  • Svitavy, Czechia, 568 25
    • Novartis Investigative Site
  • Třebíč, Czechia, 674 01
    • Novartis Investigative Site
  • Uherské Hradiště, Czechia, 686 01
    • Novartis Investigative Site
  • Zlín, Czechia, 760 01
    • Novartis Investigative Site
  • Český Krumlov, Czechia, 381 01
    • Novartis Investigative Site
  • Czech Republic
    • Louny, Czech Republic, Czechia, 440 01
      • Novartis Investigative Site
• Denmark
  • Aarhus N, Denmark, 8200
    • Novartis Investigative Site
  • Esbjerg, Denmark, 6700
    • Novartis Investigative Site
  • Glostrup Municipality, Denmark, DK-2600
    • Novartis Investigative Site
  • Herlev, Denmark, 2730
    • Novartis Investigative Site
  • Hjørring, Denmark, 9800
    • Novartis Investigative Site
  • Roskilde, Denmark, 4000
    • Novartis Investigative Site
  • Svendborg, Denmark, 5700
    • Novartis Investigative Site
  • Viborg, Denmark, 8800
    • Novartis Investigative Site
  • Central Jutland
    • Herning, Central Jutland, Denmark, 7400
      • Novartis Investigative Site
• Estonia
  • Pärnu, Estonia, 80018
    • Novartis Investigative Site
  • Tallinn, Estonia, 13419
    • Novartis Investigative Site
  • Tallinn, Estonia, 10138
    • Novartis Investigative Site
  • Tallinn, Estonia, 13619
    • Novartis Investigative Site
  • Tallinn, Estonia, 10117
    • Novartis Investigative Site
  • Tartu, Estonia, 50406
    • Novartis Investigative Site
  • Tartu, Estonia, 50708
    • Novartis Investigative Site
• Finland
  • Helsinki, Finland, 370
    • Novartis Investigative Site
  • Jyväskylä, Finland, 40620
    • Novartis Investigative Site
  • Turku, Finland, 20520
    • Novartis Investigative Site
  • Turku, Finland, 20100
    • Novartis Investigative Site
  • Northern Savonia
    • Kuopio, Northern Savonia, Finland, 70600
      • Novartis Investigative Site
• France
  • Amiens, France, 80054
    • Novartis Investigative Site
  • Brest, France, 29200
    • Novartis Investigative Site
  • Béziers, France, 34525
    • Novartis Investigative Site
  • Chambray-lès-Tours, France, 37170
    • Novartis Investigative Site
  • Cholet, France, 49325
    • Novartis Investigative Site
  • Clermont-Ferrand, France, 63003
    • Novartis Investigative Site
  • Corbeil-Essonnes, France, 91100
    • Novartis Investigative Site
  • Grenoble, France, 38043
    • Novartis Investigative Site
  • Le Coudray, France, 28630
    • Novartis Investigative Site
  • Lille, France, 59000
    • Novartis Investigative Site
  • Lyon, France, 69007
    • Novartis Investigative Site
  • Marseille, France, 13885
    • Novartis Investigative Site
  • Metz, France, 57085
    • Novartis Investigative Site
  • Montauban, France, 82017
    • Novartis Investigative Site
  • Montpellier, France, 34295
    • Novartis Investigative Site
  • Nice, France, 06000
    • Novartis Investigative Site
  • Nîmes, France, 30029
    • Novartis Investigative Site
  • Orléans, France, 45100
    • Novartis Investigative Site
  • Paris, France, 75013
    • Novartis Investigative Site
  • Paris, France, 75015
    • Novartis Investigative Site
  • Paris, France, 75010
    • Novartis Investigative Site
  • Paris, France, 75018
    • Novartis Investigative Site
  • Pau, France, 64046
    • Novartis Investigative Site
  • Pessac, France, 33604
    • Novartis Investigative Site
  • Poitiers, France, 86021
    • Novartis Investigative Site
  • Reims, France, 51092
    • Novartis Investigative Site
  • Rennes, France, 35033
    • Novartis Investigative Site
  • Toulouse, France, 31054
    • Novartis Investigative Site
  • Tourcoing, France, 59208
    • Novartis Investigative Site
  • Valenciennes, France, 59300
    • Novartis Investigative Site
  • Villeneuve-d'Ascq, France, 59650
    • Novartis Investigative Site
  • Haute Vienne
    • Limoges, Haute Vienne, France, 87000
      • Novartis Investigative Site
• Greece
  • Athens, Greece, 115 27
    • Novartis Investigative Site
  • Athens, Greece, 115 21
    • Novartis Investigative Site
  • Athens, Greece, 11528
    • Novartis Investigative Site
  • Ioannina, Greece, 455 00
    • Novartis Investigative Site
  • Larissa, Greece, 411 10
    • Novartis Investigative Site
  • Thessaloniki, Greece, 54636
    • Novartis Investigative Site
  • Thessaloniki, Greece, 570 01
    • Novartis Investigative Site
• Hungary
  • Baja, Hungary, 6500
    • Novartis Investigative Site
  • Balassagyarmat, Hungary, 2660
    • Novartis Investigative Site
  • Balatonfüred, Hungary, 8230
    • Novartis Investigative Site
  • Budapest, Hungary, H-1083
    • Novartis Investigative Site
  • Budapest, Hungary, H-1145
    • Novartis Investigative Site
  • Kalocsa, Hungary, 6300
    • Novartis Investigative Site
  • Kecskemét, Hungary, 6001
    • Novartis Investigative Site
  • Kistarcsa, Hungary, 2143
    • Novartis Investigative Site
  • Komárom, Hungary, 2921
    • Novartis Investigative Site
  • Nagykanizsa, Hungary, 8800
    • Novartis Investigative Site
  • Orosháza, Hungary, 5900
    • Novartis Investigative Site
  • Pécs, Hungary, 7623
    • Novartis Investigative Site
  • Szeged, Hungary, 6725
    • Novartis Investigative Site
  • Szekszárd, Hungary, 7100
    • Novartis Investigative Site
  • Szolnok, Hungary, 5000
    • Novartis Investigative Site
  • Zalaegerszeg, Hungary, 8900
    • Novartis Investigative Site
  • Baranya
    • Pécs, Baranya, Hungary, 7623
      • Novartis Investigative Site
  • Csongrád megye
    • Oroshaza, Csongrád megye, Hungary, 5900
      • Novartis Investigative Site
  • Hajdu Bihar Megye
    • Debrecen, Hajdu Bihar Megye, Hungary, 4032
      • Novartis Investigative Site
  • Pest County
    • Budapest, Pest County, Hungary, 1134
      • Novartis Investigative Site
• Iceland
  • Kopavogur, Iceland, 201
    • Novartis Investigative Site
  • Reykjavik, Iceland, 101
    • Novartis Investigative Site
• India
  • New Delhi, India, 110025
    • Novartis Investigative Site
  • Puducherry, India, 607402
    • Novartis Investigative Site
  • Uttarakhand, India, 263153
    • Novartis Investigative Site
  • Andhra Pradesh
    • Guntur, Andhra Pradesh, India, 522001
      • Novartis Investigative Site
    • Hyderabad, Andhra Pradesh, India, 500033
      • Novartis Investigative Site
  • Gujarat
    • Ahmedabad, Gujarat, India, 382428
      • Novartis Investigative Site
    • Ahmedabad, Gujarat, India, 380054
      • Novartis Investigative Site
    • Ahmedabad, Gujarat, India, 380060
      • Novartis Investigative Site
    • Vadodara, Gujarat, India, 390022
      • Novartis Investigative Site
  • Karnataka
    • Belagavi, Karnataka, India, 590010
      • Novartis Investigative Site
    • Manipal, Karnataka, India, 576104
      • Novartis Investigative Site
    • Mysore, Karnataka, India, 570001
      • Novartis Investigative Site
    • Mysore, Karnataka, India, 570015
      • Novartis Investigative Site
  • Kerala
    • Kochi, Kerala, India, 682041
      • Novartis Investigative Site
    • Kochi, Kerala, India, 682018
      • Novartis Investigative Site
    • Kozhikode, Kerala, India, 673008
      • Novartis Investigative Site
  • Madhyapradesh
    • Indore, Madhyapradesh, India, 452003
      • Novartis Investigative Site
  • Maharashtra
    • Mumbai, Maharashtra, India, 400012
      • Novartis Investigative Site
    • Nagpur, Maharashtra, India, 440012
      • Novartis Investigative Site
    • Nagpur, Maharashtra, India, 440033
      • Novartis Investigative Site
    • Nashik, Maharashtra, India, 422005
      • Novartis Investigative Site
    • Pune, Maharashtra, India, 411004
      • Novartis Investigative Site
    • Pune, Maharashtra, India, 411045
      • Novartis Investigative Site
  • National Capital Territory of Delhi
    • New Delhi, National Capital Territory of Delhi, India, 110060
      • Novartis Investigative Site
    • New Delhi, National Capital Territory of Delhi, India, 110076
      • Novartis Investigative Site
    • New Delhi, National Capital Territory of Delhi, India, 110075
      • Novartis Investigative Site
  • Rajasthan
    • Bikaner, Rajasthan, India, 334003
      • Novartis Investigative Site
  • Tamil Nadu
    • Chennai, Tamil Nadu, India, 600006
      • Novartis Investigative Site
    • Coimbatore, Tamil Nadu, India, 641037
      • Novartis Investigative Site
    • Coimbatore, Tamil Nadu, India, 641009
      • Novartis Investigative Site
    • Madurai, Tamil Nadu, India, 625020
      • Novartis Investigative Site
  • Telangana
    • Hyderabad, Telangana, India, 500034
      • Novartis Investigative Site
    • Secunderabad, Telangana, India, 500003
      • Novartis Investigative Site
  • Uttar Pradesh
    • Aligarh, Uttar Pradesh, India, 202002
      • Novartis Investigative Site
    • Ghaziabad, Uttar Pradesh, India, 201012
      • Novartis Investigative Site
    • Kanpur, Uttar Pradesh, India, 208002
      • Novartis Investigative Site
    • Lucknow, Uttar Pradesh, India, 226003
      • Novartis Investigative Site
    • Varanasi, Uttar Pradesh, India, 221010
      • Novartis Investigative Site
  • Uttarakhand
    • Dehradun, Uttarakhand, India, 248001
      • Novartis Investigative Site
  • Uttrakhand
    • Dehradun, Uttrakhand, India, 248104
      • Novartis Investigative Site
  • West Bengal
    • Kolkata, West Bengal, India, 700054
      • Novartis Investigative Site
• Israel
  • Ashdod, Israel, 7747629
    • Novartis Investigative Site
  • Holon, Israel, 5822012
    • Novartis Investigative Site
  • Jerusalem, Israel, 9112001
    • Novartis Investigative Site
  • Nahariya, Israel, 2210001
    • Novartis Investigative Site
  • Petah Tikva, Israel, 4941492
    • Novartis Investigative Site
  • Ramat Gan, Israel, 5265601
    • Novartis Investigative Site
  • Sefad, Israel, 1311300
    • Novartis Investigative Site
  • Ẕerifin, Israel, 7030000
    • Novartis Investigative Site
• Italy
  • BO
    • Bologna, BO, Italy, 40138
      • Novartis Investigative Site
    • Bologna, BO, Italy, 40133
      • Novartis Investigative Site
  • BS
    • Brescia, BS, Italy, 25123
      • Novartis Investigative Site
  • FE
    • Cona, FE, Italy, 44124
      • Novartis Investigative Site
  • FI
    • Florence, FI, Italy, 50134
      • Novartis Investigative Site
  • GR
    • Grosseto, GR, Italy, 58100
      • Novartis Investigative Site
  • IS
    • Pozzilli, IS, Italy, 86077
      • Novartis Investigative Site
  • MI
    • Milan, MI, Italy, 20162
      • Novartis Investigative Site
    • Milan, MI, Italy, 20132
      • Novartis Investigative Site
    • Milan, MI, Italy, 20138
      • Novartis Investigative Site
    • Rozzano, MI, Italy, 20089
      • Novartis Investigative Site
  • MO
    • Modena, MO, Italy, 41126
      • Novartis Investigative Site
  • PN
    • Pordenone, PN, Italy, 33170
      • Novartis Investigative Site
  • SI
    • Siena, SI, Italy, 53100
      • Novartis Investigative Site
  • SS
    • Sassari, SS, Italy, 07100
      • Novartis Investigative Site
  • TO
    • Torino, TO, Italy, 10126
      • Novartis Investigative Site
• Japan
  • Aichi-ken
    • Toyota, Aichi-ken, Japan, 471-8513
      • Novartis Investigative Site
  • Fukuka
    • Chikushino-shi, Fukuka, Japan, 818-8516
      • Novartis Investigative Site
  • Ishikawa-ken
    • Kanazawa, Ishikawa-ken, Japan, 9208650
      • Novartis Investigative Site
    • Komatsu, Ishikawa-ken, Japan, 923-0961
      • Novartis Investigative Site
  • Kanagawa
    • Fujisawa, Kanagawa, Japan, 2518550
      • Novartis Investigative Site
    • Odawara, Kanagawa, Japan, 2508558
      • Novartis Investigative Site
    • Yokohama, Kanagawa, Japan, 247-8581
      • Novartis Investigative Site
  • Nagasaki
    • Nagasaki, Nagasaki, Japan, 8508555
      • Novartis Investigative Site
  • Niigata
    • Nagaoka, Niigata, Japan, 940-8621
      • Novartis Investigative Site
  • Osaka
    • Izumisano, Osaka, Japan, 5988577
      • Novartis Investigative Site
    • Osaka, Osaka, Japan, 5400006
      • Novartis Investigative Site
  • Saitama
    • Kawaguchi, Saitama, Japan, 332-8558
      • Novartis Investigative Site
• Kenya
  • Nairobi, Kenya, 00200
    • Novartis Investigative Site
• Latvia
  • Daugavpils, Latvia, LV-5417
    • Novartis Investigative Site
  • Kuldīga, Latvia, LV-3300
    • Novartis Investigative Site
  • Riga, Latvia, LV 1002
    • Novartis Investigative Site
  • Riga, Latvia, 1012
    • Novartis Investigative Site
  • Riga, Latvia, LV-1001
    • Novartis Investigative Site
  • Valmiera, Latvia, 4201
    • Novartis Investigative Site
  • LV
    • Liepāja, LV, Latvia, LV-3414
      • Novartis Investigative Site
    • Riga, LV, Latvia, 1038
      • Novartis Investigative Site
• Lithuania
  • Kaunas, Lithuania, LT-50009
    • Novartis Investigative Site
  • Kaunas, Lithuania, 49449
    • Novartis Investigative Site
  • Panevezys, Lithuania, 35144
    • Novartis Investigative Site
  • Vilnius, Lithuania, LT-08406
    • Novartis Investigative Site
  • Šiauliai, Lithuania, 76206
    • Novartis Investigative Site
  • Kaunas County
    • Kaunas, Kaunas County, Lithuania, LT-50177
      • Novartis Investigative Site
  • Klaipėda County
    • Klaipėda, Klaipėda County, Lithuania, 92288
      • Novartis Investigative Site
  • LTU
    • Kaunas, LTU, Lithuania, LT 50161
      • Novartis Investigative Site
    • Šiauliai, LTU, Lithuania, LT-77156
      • Novartis Investigative Site
• Malaysia
  • Kuala Lumpur, Malaysia, 59100
    • Novartis Investigative Site
  • Kuala Lumpur, Malaysia, 56000
    • Novartis Investigative Site
  • Kedah
    • Alor Star, Kedah, Malaysia, 05460
      • Novartis Investigative Site
  • Pahang
    • Kuantan, Pahang, Malaysia, 25100
      • Novartis Investigative Site
  • Perak
    • Ipoh, Perak, Malaysia, 30450
      • Novartis Investigative Site
  • Selangor
    • Kuala Lumpur, Selangor, Malaysia, 43000
      • Novartis Investigative Site
• Mauritius
  • Phoenix, Mauritius, 73408
    • Novartis Investigative Site
  • Mauritius
    • Solferino Phoenix, Mauritius, Mauritius, 1772
      • Novartis Investigative Site
• Mexico
  • Acapulco, Mexico, 39570
    • Novartis Investigative Site
  • Aguascalientes, Mexico, 20230
    • Novartis Investigative Site
  • Durango, Mexico, 34000
    • Novartis Investigative Site
  • Guadalajara, Mexico, 44360
    • Novartis Investigative Site
  • Xalapa, Mexico, 91020
    • Novartis Investigative Site
  • Xalapa, Mexico, 91193
    • Novartis Investigative Site
  • Aguascalientes
    • Aguascalientes, Aguascalientes, Mexico, 20230
      • Novartis Investigative Site
  • Chihuahua
    • Chihuahua City, Chihuahua, Mexico, 31203
      • Novartis Investigative Site
  • Jalisco
    • Guadalajara, Jalisco, Mexico, 44670
      • Novartis Investigative Site
    • Guadalajara, Jalisco, Mexico, 44600
      • Novartis Investigative Site
    • Guadalajara, Jalisco, Mexico, 44210
      • Novartis Investigative Site
  • Mexico City
    • Mexico City, Mexico City, Mexico, 06700
      • Novartis Investigative Site
  • Nuevo León
    • Monterrey, Nuevo León, Mexico, 64710
      • Novartis Investigative Site
  • State of Mexico
    • Tlalnepantla, State of Mexico, Mexico, 54055
      • Novartis Investigative Site
  • Yucatán
    • Mérida, Yucatán, Mexico, 97070
      • Novartis Investigative Site
• Netherlands
  • Amersfoort, Netherlands, 3813 TZ
    • Novartis Investigative Site
  • Gouda, Netherlands, 2803 HH
    • Novartis Investigative Site
  • Venlo, Netherlands, 5912 BL
    • Novartis Investigative Site
  • Drenthe
    • Meppel, Drenthe, Netherlands, 7943 KC
      • Novartis Investigative Site
  • Gelderland
    • Doetinchem, Gelderland, Netherlands, 7009 BL
      • Novartis Investigative Site
    • Nijmegen, Gelderland, Netherlands, 6500HB
      • Novartis Investigative Site
    • Tiel, Gelderland, Netherlands, 4002 WP
      • Novartis Investigative Site
  • Gerlderland
    • Nijmegen, Gerlderland, Netherlands, 6532 SZ
      • Novartis Investigative Site
  • North Brabant
    • Breda, North Brabant, Netherlands, 4818 CK
      • Novartis Investigative Site
    • Tilburg, North Brabant, Netherlands, 5042 AD
      • Novartis Investigative Site
  • North Holland
    • Alkmaar, North Holland, Netherlands, 1815 JD
      • Novartis Investigative Site
    • Amstelveen, North Holland, Netherlands, 1186 AM
      • Novartis Investigative Site
    • Amsterdam, North Holland, Netherlands, 1090 HM
      • Novartis Investigative Site
    • Amsterdam, North Holland, Netherlands, 1105 AZ
      • Novartis Investigative Site
    • Heemstede, North Holland, Netherlands, 2035 RC
      • Novartis Investigative Site
  • Overijssel
    • Deventer, Overijssel, Netherlands, 7416 SE
      • Novartis Investigative Site
  • Provincie Friesland
    • Leeuwarden, Provincie Friesland, Netherlands, 8934 AD
      • Novartis Investigative Site
    • Sneek, Provincie Friesland, Netherlands, 8601 ZK
      • Novartis Investigative Site
  • Provincie Groningen
    • Groningen, Provincie Groningen, Netherlands, 9713 GZ
      • Novartis Investigative Site
    • Groningen, Provincie Groningen, Netherlands, 9728 NZ
      • Novartis Investigative Site
  • South Holland
    • Leiden, South Holland, Netherlands, 2333 ZA
      • Novartis Investigative Site
    • Leiderdorp, South Holland, Netherlands, 2353 GA
      • Novartis Investigative Site
• New Zealand
  • Auckland, New Zealand, 740
    • Novartis Investigative Site
  • Christchurch, New Zealand, 8140
    • Novartis Investigative Site
  • Hamilton, New Zealand, 3240
    • Novartis Investigative Site
  • Lower Hutt, New Zealand, 5040
    • Novartis Investigative Site
  • Auckland
    • Grafton, Auckland, New Zealand, 1023
      • Novartis Investigative Site
  • Christchurch
    • Christchurch, Christchurch, New Zealand, 8001
      • Novartis Investigative Site
  • NZW
    • Dunedin, NZW, New Zealand, 9016
      • Novartis Investigative Site
• Norway
  • Arendal, Norway, 4838
    • Novartis Investigative Site
  • Drammen, Norway, 3004
    • Novartis Investigative Site
  • Oslo, Norway, 0514
    • Novartis Investigative Site
  • Oslo, Norway, NO-0407
    • Novartis Investigative Site
  • Skedsmokorset, Norway, 2020
    • Novartis Investigative Site
  • Tromsø, Norway, 9038
    • Novartis Investigative Site
  • Oslo
    • Nordbyhagen, Oslo, Norway, 1478
      • Novartis Investigative Site
  • Stavanger
    • Stavanger, Stavanger, Norway, 4019
      • Novartis Investigative Site
• Philippines
  • Quezon, Philippines, 1102
    • Novartis Investigative Site
  • San Juan City, Philippines, 1502
    • Novartis Investigative Site
  • Iloilo
    • Iloilo City, Iloilo, Philippines, 5000
      • Novartis Investigative Site
  • Pampanga
    • San Fernando City, Pampanga, Philippines, 2000
      • Novartis Investigative Site
• Poland
  • Bialystok, Poland, 15-540
    • Novartis Investigative Site
  • Bialystok, Poland, 15-481
    • Novartis Investigative Site
  • Bydgoszcz, Poland, 85-065
    • Novartis Investigative Site
  • Gdynia, Poland, 81-423
    • Novartis Investigative Site
  • Kielce, Poland, 25-525
    • Novartis Investigative Site
  • Krakow, Poland, 31-501
    • Novartis Investigative Site
  • Krakow, Poland, 30-082
    • Novartis Investigative Site
  • Krakow, Poland, 30-363
    • Novartis Investigative Site
  • Kłodzko, Poland, 57-300
    • Novartis Investigative Site
  • Lodz, Poland, 93-513
    • Novartis Investigative Site
  • Lublin, Poland, 20-068
    • Novartis Investigative Site
  • Olsztyn, Poland, 10-165
    • Novartis Investigative Site
  • Ostrowiec Swietok, Poland, 27-400
    • Novartis Investigative Site
  • Puławy, Poland, 24-100
    • Novartis Investigative Site
  • Ruda Śląska, Poland, 41-710
    • Novartis Investigative Site
  • Skierniewice, Poland, 96-100
    • Novartis Investigative Site
  • Torun, Poland, 87-100
    • Novartis Investigative Site
  • Warsaw, Poland, 00-416
    • Novartis Investigative Site
  • Warsaw, Poland, 01 813
    • Novartis Investigative Site
  • Warsaw, Poland, 04-073
    • Novartis Investigative Site
  • Włocławek, Poland, 87-800
    • Novartis Investigative Site
  • Zamość, Poland, 22-400
    • Novartis Investigative Site
  • Lesser Poland Voivodeship
    • Nowy Targ, Lesser Poland Voivodeship, Poland, 34-400
      • Novartis Investigative Site
  • Masovian Voivodeship
    • Ostrołęka, Masovian Voivodeship, Poland, 07-410
      • Novartis Investigative Site
  • Silesian Voivodeship
    • Sosnowiec, Silesian Voivodeship, Poland, 41-219
      • Novartis Investigative Site
• Portugal
  • Alcabideche, Portugal, 2755-009
    • Novartis Investigative Site
  • Almada, Portugal, 2805-267
    • Novartis Investigative Site
  • Carnaxide, Portugal, 2799-523
    • Novartis Investigative Site
  • Coimbra, Portugal, 3004-561
    • Novartis Investigative Site
  • Guimarães, Portugal, 4835-044
    • Novartis Investigative Site
  • Leiria, Portugal, 2410-197
    • Novartis Investigative Site
  • Lisbon, Portugal, 1500 650
    • Novartis Investigative Site
  • Lisbon, Portugal, 1649-035
    • Novartis Investigative Site
  • Matosinhos Municipality, Portugal, 4454-513
    • Novartis Investigative Site
  • Santa Maria da Feira, Portugal, 4520-211
    • Novartis Investigative Site
  • Vila Nova de Gaia, Portugal, 4434 502
    • Novartis Investigative Site
  • Vila Real, Portugal, 5000-508
    • Novartis Investigative Site
• Puerto Rico
  • Bayamón, Puerto Rico, 00959
    • Advanced Clinical Research LLC
  • Ponce, Puerto Rico, 00717-1322
    • Research and Cardiovascular Corp
  • San Juan, Puerto Rico, 00926
    • Advance Medical Research Center
  • San Juan, Puerto Rico, 00909
    • Latin Clinical Trial Center Inc
  • San Juan, Puerto Rico, 00926
    • Barbara Diaz Hernandez Research Inc
• Romania
  • Brasov, Romania, 500283
    • Novartis Investigative Site
  • Bucharest, Romania, 022328
    • Novartis Investigative Site
  • Bucharest, Romania, 050098
    • Novartis Investigative Site
  • Bucharest, Romania, 021659
    • Novartis Investigative Site
  • Bucharest, Romania, 011461
    • Novartis Investigative Site
  • Bucharest, Romania, 011025
    • Novartis Investigative Site
  • Caracal, Romania, 235200
    • Novartis Investigative Site
  • Craiova, Romania, 200642
    • Novartis Investigative Site
  • Iași, Romania, 700503
    • Novartis Investigative Site
  • Timișoara, Romania, 300079
    • Novartis Investigative Site
  • Timișoara, Romania, 300359
    • Novartis Investigative Site
  • Târgu Mureş, Romania, 540143
    • Novartis Investigative Site
  • Argeş
    • Piteşti, Argeş, Romania, 110424
      • Novartis Investigative Site
  • Maramureş
    • Baia Mare, Maramureş, Romania, 430123
      • Novartis Investigative Site
  • Mureș County
    • Târgu Mureş, Mureș County, Romania, 540124
      • Novartis Investigative Site
  • Oradea
    • Oradea, Oradea, Romania, 410169
      • Novartis Investigative Site
  • ROM
    • Brăila, ROM, Romania, 810249
      • Novartis Investigative Site
  • Timiș County
    • Timișoara, Timiș County, Romania, 300041
      • Novartis Investigative Site
    • Timișoara, Timiș County, Romania, 300480
      • Novartis Investigative Site
• Russia
  • Moscow, Russia, 127473
    • Novartis Investigative Site
  • Ryazan, Russia, 390039
    • Novartis Investigative Site
  • Saint Petersburg, Russia, 195197
    • Novartis Investigative Site
  • Yaroslavl, Russia, 150062
    • Novartis Investigative Site
• Serbia
  • Belgrade, Serbia, 11000
    • Novartis Investigative Site
  • Kragujevac, Serbia, 34000
    • Novartis Investigative Site
  • Leskovac, Serbia, 16000
    • Novartis Investigative Site
  • Niš, Serbia, 18000
    • Novartis Investigative Site
  • Smederevo, Serbia, 26000
    • Novartis Investigative Site
  • Subotica, Serbia, 24000
    • Novartis Investigative Site
  • Vranje, Serbia, 17500
    • Novartis Investigative Site
  • Zaječar, Serbia, 19000
    • Novartis Investigative Site
  • Ćuprija, Serbia, 35230
    • Novartis Investigative Site
  • Serbia
    • Belgrade, Serbia, Serbia, 11000
      • Novartis Investigative Site
    • Belgrade, Serbia, Serbia, 11080
      • Novartis Investigative Site
    • Kamenitz, Serbia, Serbia, 21204
      • Novartis Investigative Site
• Singapore
  • Singapore, Singapore, 119074
    • Novartis Investigative Site
  • Singapore, Singapore, 529889
    • Novartis Investigative Site
  • Singapore, Singapore, 169609
    • Novartis Investigative Site
  • Singapore
    • Singapore, Singapore, Singapore, 768828
      • Novartis Investigative Site
• Slovakia
  • Banská Bystrica, Slovakia, 974 01
    • Novartis Investigative Site
  • Bardejov, Slovakia, 085 01
    • Novartis Investigative Site
  • Bratislava, Slovakia, 831 06
    • Novartis Investigative Site
  • Bratislava, Slovakia, 833 48
    • Novartis Investigative Site
  • Bratislava, Slovakia, 851 01
    • Novartis Investigative Site
  • Bratislava, Slovakia, 841 08
    • Novartis Investigative Site
  • Košice, Slovakia, 040 01
    • Novartis Investigative Site
  • Košice, Slovakia, 040 22
    • Novartis Investigative Site
  • Lučenec, Slovakia, 984 01
    • Novartis Investigative Site
  • Moldava nad Bodvou, Slovakia, 045 01
    • Novartis Investigative Site
  • Nitra, Slovakia, 949 01
    • Novartis Investigative Site
  • Nitra, Slovakia, 949 11
    • Novartis Investigative Site
  • Nové Zámky, Slovakia, 940 01
    • Novartis Investigative Site
  • Piešťany, Slovakia, 921 01
    • Novartis Investigative Site
  • Považská Bystrica, Slovakia, 017 01
    • Novartis Investigative Site
  • Prešov, Slovakia, 080 01
    • Novartis Investigative Site
  • Rožňava, Slovakia, 048 01
    • Novartis Investigative Site
  • Žilina, Slovakia, 010 01
    • Novartis Investigative Site
  • Slovakia
    • Bratislava, Slovakia, Slovakia, 813 69
      • Novartis Investigative Site
    • Bratislava, Slovakia, Slovakia, 826 06
      • Novartis Investigative Site
    • Košice, Slovakia, Slovakia, 040 01
      • Novartis Investigative Site
• Slovenia
  • Celje, Slovenia, 3000
    • Novartis Investigative Site
  • Ljubljana, Slovenia, 1000
    • Novartis Investigative Site
  • Ptuj, Slovenia, 2250
    • Novartis Investigative Site
  • Slovenj Gradec, Slovenia, 2380
    • Novartis Investigative Site
• South Africa
  • Bloemfontein, South Africa, 9301
    • Novartis Investigative Site
  • Cape Town, South Africa, 7500
    • Novartis Investigative Site
  • Midrand, South Africa, 1685
    • Novartis Investigative Site
  • Pretoria, South Africa, 0181
    • Novartis Investigative Site
  • Centurion
    • Raslouw, Centurion, South Africa, 0157
      • Novartis Investigative Site
  • Free State
    • Bloemfontein, Free State, South Africa, 9301
      • Novartis Investigative Site
  • Gauteng
    • Germiston, Gauteng, South Africa, 1401
      • Novartis Investigative Site
    • Pretoria, Gauteng, South Africa, 0184
      • Novartis Investigative Site
    • Pretoria, Gauteng, South Africa, 0002
      • Novartis Investigative Site
    • Soweto, Gauteng, South Africa, 2013
      • Novartis Investigative Site
    • Vereeniging, Gauteng, South Africa, 1939
      • Novartis Investigative Site
  • Western Cape
    • Cape Town, Western Cape, South Africa, 7530
      • Novartis Investigative Site
    • Cape Town, Western Cape, South Africa, 7130
      • Novartis Investigative Site
    • George, Western Cape, South Africa, 6529
      • Novartis Investigative Site
    • Paarl, Western Cape, South Africa, 7626
      • Novartis Investigative Site
    • Somerset West, Western Cape, South Africa, 7130
      • Novartis Investigative Site
    • Worcester, Western Cape, South Africa, 6850
      • Novartis Investigative Site
  • ZAF
    • Cape Town, ZAF, South Africa, 7570
      • Novartis Investigative Site
• South Korea
  • Busan, South Korea, 49201
    • Novartis Investigative Site
  • Daegu, South Korea, 705703
    • Novartis Investigative Site
  • Daejeon, South Korea, 302-241
    • Novartis Investigative Site
  • Gwangju, South Korea, 61469
    • Novartis Investigative Site
  • Seoul, South Korea, 03722
    • Novartis Investigative Site
  • Seoul, South Korea, 06591
    • Novartis Investigative Site
  • Dalseo gu
    • Daegu, Dalseo gu, South Korea, 42602
      • Novartis Investigative Site
  • Gangwon-do
    • Wŏnju, Gangwon-do, South Korea, 26426
      • Novartis Investigative Site
  • Gyeonggi-do
    • Bundang Gu, Gyeonggi-do, South Korea, 13620
      • Novartis Investigative Site
  • Gyeongsangnam-do
    • Jinju, Gyeongsangnam-do, South Korea, 52727
      • Novartis Investigative Site
    • Yangsan, Gyeongsangnam-do, South Korea, 50612
      • Novartis Investigative Site
  • Korea
    • Incheon, Korea, South Korea, 405 760
      • Novartis Investigative Site
    • Seoul, Korea, South Korea, 02447
      • Novartis Investigative Site
    • Seoul, Korea, South Korea, 08308
      • Novartis Investigative Site
  • North Chungcheong
    • Cheongju-si, North Chungcheong, South Korea, 28644
      • Novartis Investigative Site
  • Seoul
    • Seoul, Seoul, South Korea, 06351
      • Novartis Investigative Site
    • Seoul, Seoul, South Korea, 03080
      • Novartis Investigative Site
• Spain
  • A Coruña, Spain, 15006
    • Novartis Investigative Site
  • A Coruña, Spain, 15001
    • Novartis Investigative Site
  • Alicante, Spain, 03700
    • Novartis Investigative Site
  • Almería, Spain, 04009
    • Novartis Investigative Site
  • Barcelona, Spain, 08035
    • Novartis Investigative Site
  • Barcelona, Spain, 08036
    • Novartis Investigative Site
  • Barcelona, Spain, 08041
    • Novartis Investigative Site
  • Barcelona, Spain, 08025
    • Novartis Investigative Site
  • Barcelona, Spain, 08023
    • Novartis Investigative Site
  • Córdoba, Spain, 14004
    • Novartis Investigative Site
  • Granada, Spain, 18016
    • Novartis Investigative Site
  • Huelva, Spain, 21080
    • Novartis Investigative Site
  • Las Palmas GC, Spain, 35010
    • Novartis Investigative Site
  • Madrid, Spain, 28041
    • Novartis Investigative Site
  • Madrid, Spain, 28034
    • Novartis Investigative Site
  • Madrid, Spain, 28046
    • Novartis Investigative Site
  • Madrid, Spain, 28006
    • Novartis Investigative Site
  • Madrid, Spain, 28040
    • Novartis Investigative Site
  • Madrid, Spain, 28009
    • Novartis Investigative Site
  • Madrid, Spain, 28003
    • Novartis Investigative Site
  • Málaga, Spain, 29010
    • Novartis Investigative Site
  • Salamanca, Spain, 37007
    • Novartis Investigative Site
  • Salamanca, Spain, 37005
    • Novartis Investigative Site
  • Seville, Spain, 41009
    • Novartis Investigative Site
  • Seville, Spain, 41013
    • Novartis Investigative Site
  • Valencia, Spain, 46014
    • Novartis Investigative Site
  • Valencia, Spain, 46010
    • Novartis Investigative Site
  • Valladolid, Spain, 47011
    • Novartis Investigative Site
  • Zaragoza, Spain, 50009
    • Novartis Investigative Site
  • A Coruna
    • Ferrol, A Coruna, Spain, 15405
      • Novartis Investigative Site
    • Santiago Compostela, A Coruna, Spain, 15706
      • Novartis Investigative Site
  • Andalusia
    • Seville, Andalusia, Spain, 41014
      • Novartis Investigative Site
  • Balearic Islands
    • Mallorca, Balearic Islands, Spain, 07198
      • Novartis Investigative Site
    • Palma, Balearic Islands, Spain, 07120
      • Novartis Investigative Site
  • Barcelona
    • L'Hospitalet de Llobregat, Barcelona, Spain, 08907
      • Novartis Investigative Site
    • Sabadell, Barcelona, Spain, 08208
      • Novartis Investigative Site
    • Sant Joan Despí, Barcelona, Spain, 08970
      • Novartis Investigative Site
    • el Prat de Llobregat, Barcelona, Spain, 08820
      • Novartis Investigative Site
  • Bizkaia
    • Bilbao, Bizkaia, Spain, 48013
      • Novartis Investigative Site
  • Cadiz
    • Jerez de la Frontera, Cadiz, Spain, 11407
      • Novartis Investigative Site
    • Villamartín, Cadiz, Spain, 11650
      • Novartis Investigative Site
  • Cantabria
    • Santander, Cantabria, Spain, 39008
      • Novartis Investigative Site
  • Madrid
    • Alcorcón, Madrid, Spain, 28922
      • Novartis Investigative Site
    • San Sebastian Reyes, Madrid, Spain, 28702
      • Novartis Investigative Site
  • Murcia
    • El Palmar, Murcia, Spain, 30120
      • Novartis Investigative Site
  • Pontevedra
    • Vigo, Pontevedra, Spain, 36212
      • Novartis Investigative Site
  • Sevilla
    • Utrera, Sevilla, Spain, 41710
      • Novartis Investigative Site
  • Tarragona
    • Reus, Tarragona, Spain, 43201
      • Novartis Investigative Site
• Sweden
  • Falun, Sweden, 791 82
    • Novartis Investigative Site
  • Gothenburg, Sweden, SE-412 55
    • Novartis Investigative Site
  • Lund, Sweden, 221 85
    • Novartis Investigative Site
  • Malmö, Sweden, 214 28
    • Novartis Investigative Site
  • Stockholm, Sweden, 111 57
    • Novartis Investigative Site
  • Stockholm, Sweden, 17176
    • Novartis Investigative Site
  • Västerås, Sweden, 721 89
    • Novartis Investigative Site
  • SE
    • Stockholm, SE, Sweden, 141 86
      • Novartis Investigative Site
  • Västra Götaland County
    • Gothenburg, Västra Götaland County, Sweden, 416 85
      • Novartis Investigative Site
• Taiwan
  • Kaohsiung City, Taiwan, 80756
    • Novartis Investigative Site
  • Tainan, Taiwan, 71004
    • Novartis Investigative Site
  • Tainan, Taiwan, 704302
    • Novartis Investigative Site
  • Taipei, Taiwan, 10002
    • Novartis Investigative Site
  • Taipei, Taiwan, 11217
    • Novartis Investigative Site
  • Taipei, Taiwan, 10449
    • Novartis Investigative Site
  • Taipei, Taiwan, 110
    • Novartis Investigative Site
• Thailand
  • Bangkok, Thailand, 10700
    • Novartis Investigative Site
  • Bangkok, Thailand, 10400
    • Novartis Investigative Site
  • Chiang Mai, Thailand, 50200
    • Novartis Investigative Site
  • Muang, Thailand, 40002
    • Novartis Investigative Site
  • Hat Yai
    • Songkhla, Hat Yai, Thailand, 90110
      • Novartis Investigative Site
  • Thailand
    • Muang, Thailand, Thailand, 12120
      • Novartis Investigative Site
• Turkey (Türkiye)
  • Istanbul, Turkey (Türkiye), 34147
    • Novartis Investigative Site
  • Balcova
    • Izmir, Balcova, Turkey (Türkiye), 35340
      • Novartis Investigative Site
  • Fatih
    • Istanbul, Fatih, Turkey (Türkiye), 34098
      • Novartis Investigative Site
  • Kartal
    • Istanbul, Kartal, Turkey (Türkiye), 34865
      • Novartis Investigative Site
  • Nilufer
    • Bursa, Nilufer, Turkey (Türkiye), 16140
      • Novartis Investigative Site
  • Selcuklu
    • Konya, Selcuklu, Turkey (Türkiye), 42130
      • Novartis Investigative Site
  • Sihhiye-Altindag
    • Ankara, Sihhiye-Altindag, Turkey (Türkiye), 06230
      • Novartis Investigative Site
  • Yenimahalle
    • Ankara, Yenimahalle, Turkey (Türkiye), 06170
      • Novartis Investigative Site
  • Yuregir
    • Adana, Yuregir, Turkey (Türkiye), 01230
      • Novartis Investigative Site
• United States
  • Alabama
    • Birmingham, Alabama, United States, 35211
      • UAB St Vincents
    • Fairhope, Alabama, United States, 36532
      • Eastern Shore Research Institute
    • Foley, Alabama, United States, 36535
      • G and L Research LLC
  • Alaska
    • Anchorage, Alaska, United States, 99508
      • Alaska Heart and Vascular
  • Arizona
    • Gilbert, Arizona, United States, 85297
      • Mercy Gilbert Medical Center
    • Mesa, Arizona, United States, 85206
      • CardioVascular Associates of Mesa
    • Phoenix, Arizona, United States, 85018
      • Elite Clinical Studies
    • Scottsdale, Arizona, United States, 85258
      • HonorHealth Heart Group Deer Valley
    • Sun City West, Arizona, United States, 85375
      • Clinical Research Inst of Arizona
    • Tucson, Arizona, United States, 85741
      • Pima Heart And Vascular Clin Rch
  • Arkansas
    • Little Rock, Arkansas, United States, 72205
      • Arkansas Clinical Research
    • Little Rock, Arkansas, United States, 72205
      • ARcare Center for Clinical Research
  • California
    • Bakersfield, California, United States, 93308
      • Central Cardiology Medical Center
    • Canoga Park, California, United States, 91303
      • Alliance Clinical
    • Chino, California, United States, 91710
      • Inland Psychiatric Medical Group
    • Concord, California, United States, 94520
      • John Muir Physician Network Clinical Research Center
    • Fullerton, California, United States, 92835
      • Triallogix
    • Huntington Beach, California, United States, 92648
      • Diabetes Lipid Management Center
    • Irvine, California, United States, 92660
      • University of Calif Irvine Med Cntr
    • La Jolla, California, United States, 92037
      • UC San Diego Health
    • Los Angeles, California, United States, 90017
      • American Institute of Research
    • Los Angeles, California, United States, 90095
      • University of California LA
    • Los Angeles, California, United States, 90033
      • Keck Medical Center USC
    • Palo Alto, California, United States, 94304-1207
      • VA Palo Alto Health Care System
    • San Diego, California, United States, 92161
      • San Diego Veterans Medical Center
    • San Ramon, California, United States, 94582
      • West Coast Research LLC
    • Santa Ana, California, United States, 92705
      • Syrentis Clinical Research
    • Santa Ana, California, United States, 92704
      • Helping Hands Medical Associates INC
    • Spring Valley, California, United States, 91978
      • Encompass Clinical Research
    • Stanford, California, United States, 94304
      • Stanford University Medical Center
    • Stockton, California, United States, 95204
      • Manshadi Heart Institute
    • Torrance, California, United States, 90502
      • Harbor UCLA Medical Center
    • Vista, California, United States, 92081
      • Blue Coast Research Center LLC
    • West Hills, California, United States, 91307
      • Interv Cardiology Med Grp
  • Colorado
    • Aurora, Colorado, United States, 80012
      • Aurora Denver Cardiology Associates
    • Aurora, Colorado, United States, 80045
      • Rocky Mountain Regional VA Med Ctr
  • Connecticut
    • Bridgeport, Connecticut, United States, 06610
      • Bridgeport Hospital
    • Greenwich, Connecticut, United States, 06830
      • d-b-a Greenwich Cardio Assoc
    • Waterbury, Connecticut, United States, 06708
      • Chase Medical Research LLC
  • District of Columbia
    • Washington D.C., District of Columbia, United States, 20020
      • Emerson Clinical Research Institute
  • Florida
    • Boca Raton, Florida, United States, 33434
      • Excel Medical Clinical Trials LLC
    • Bradenton, Florida, United States, 34209
      • Cardiovascular and Vein Center of Florida
    • Bradenton, Florida, United States, 34209
      • Nova Clinical Research LLC
    • Clearwater, Florida, United States, 33756
      • Bay Care Medical Group
    • Daytona Beach, Florida, United States, 32117
      • Cardiology Research Associates
    • DeLand, Florida, United States, 32720
      • Hillcrest Medical Research
    • Hialeah, Florida, United States, 33012
      • Indago Research and Health Ctr Inc
    • Hialeah, Florida, United States, 33013
      • National Research Institute
    • Hialeah, Florida, United States, 33013
      • Sister Life Research Inc
    • Hollywood, Florida, United States, 33021
      • Zenith Clinical Research
    • Jacksonville, Florida, United States, 32205
      • Westside Center for Clinical Research
    • Jacksonville, Florida, United States, 32209
      • UF Health Science Center
    • Jacksonville Beach, Florida, United States, 32250
      • Baptist Heart Specialists
    • Lake Worth, Florida, United States, 33461
      • United Vein and Vascular Centers
    • Miami, Florida, United States, 33133
      • Infinite Clinical Research
    • Miami, Florida, United States, 33186
      • A&A Research Group Inc
    • Miami Lakes, Florida, United States, 33014
      • Inpatient Research Clinical LLC
    • Miami Lakes, Florida, United States, 33014
      • RM Medical Research Inc
    • Miramar, Florida, United States, 33027
      • FXM Clin Res Miramar LLC
    • Naples, Florida, United States, 34102
      • Advanced Research for Health Improvement LLC
    • Ocala, Florida, United States, 34471
      • Ocala Cardiovascular Research
    • Oviedo, Florida, United States, 32765
      • Oviedo Medical Research
    • Palm Springs, Florida, United States, 33406
      • CTMD Research
    • Pembroke Pines, Florida, United States, 33024
      • Broward Research Center
    • Pensacola, Florida, United States, 32503
      • SEC Clinical Research
    • Port Charlotte, Florida, United States, 33952
      • Peace River Cardiovascular Center
    • St. Petersburg, Florida, United States, 33713
      • Advanced Medical Research Center
    • Tampa, Florida, United States, 33614
      • BayCare Medical Group Inc
    • Tampa, Florida, United States, 33614
      • Genesis Clinical Research
    • Tampa, Florida, United States, 33603
      • New Tampa Health
    • Tampa, Florida, United States, 33880
      • Ravessa Clinical Research
    • Tampa, Florida, United States, 33612
      • James A Haley Veterans Hospital
    • Tampa, Florida, United States, 33705
      • BayCare Health System
    • Wellington, Florida, United States, 33449
      • Cardiology Partners Clinical Research Institute
  • Georgia
    • Fayetteville, Georgia, United States, 30214
      • Javara Research
    • Gainsville, Georgia, United States, 30501
      • Northeast Georgia Medical Center
    • Peachtree Corners, Georgia, United States, 30092
      • Alta Pharmaceutical Research Center
    • Tucker, Georgia, United States, 30084
      • Atlanta Heart Specialists LLC
  • Idaho
    • Meridian, Idaho, United States, 83646
      • Solaris Clinical Research
    • Nampa, Idaho, United States, 83686
      • Saltzer Health
  • Illinois
    • Addison, Illinois, United States, 60101
      • Biofortis Research
    • Arlington Heights, Illinois, United States, 60005
      • Endeavor Health Clinical Op- NCH
    • Chicago, Illinois, United States, 60607
      • Cedar Crosse Research Ct
    • Chicago, Illinois, United States, 60607
      • Chicago Clinical Research Inst
    • Jerseyville, Illinois, United States, 62052
      • Gateway Cardiology PC
    • Peoria, Illinois, United States, 61603
      • Methodist Med Center Of Illinois
    • Springfield, Illinois, United States, 62702
      • SIU School of Medicine
    • Springfield, Illinois, United States, 62769
      • Prairie Heart Institute
  • Indiana
    • Elkhart, Indiana, United States, 46514
      • Elkhart Cardiology Group
    • Indianapolis, Indiana, United States, 46237
      • Franciscan Health Services Research Center
    • Lebanon, Indiana, United States, 46052
      • Witham Heart Partners
    • Merrillville, Indiana, United States, 46410
      • The Heart Center of Lake County
    • Munster, Indiana, United States, 46321
      • Cardiovascular Research Of Northwest Indiana, Llc
  • Iowa
    • Waterloo, Iowa, United States, 50702
      • Covenant Medical Center
  • Kansas
    • Kansas City, Kansas, United States, 66160
      • University of Kansas Hospital
    • Overland Park, Kansas, United States, 66211
      • Midwest Heart and Vascular Spec
    • Topeka, Kansas, United States, 66606
      • Cotton O Neil Clinical Res Center
    • Wichita, Kansas, United States, 67214
      • Ascension via Christi Research
  • Kentucky
    • Lexington, Kentucky, United States, 40536
      • University of Kentucky College of Health Sciences
    • Louisville, Kentucky, United States, 40202
      • U of Louisville Rudd Heart and Lung
  • Louisiana
    • Alexandria, Louisiana, United States, 71301
      • Christus Health Central Louisiana
    • Baton Rouge, Louisiana, United States, 70808
      • Louisiana Cardiology Associates
    • Bossier City, Louisiana, United States, 71111
      • Grace Research Llc
    • Covington, Louisiana, United States, 70433
      • Cardiovascular Associates Research
    • Covington, Louisiana, United States, 70433
      • Louisiana Heart Center Research
    • Crowley, Louisiana, United States, 70526
      • Avant Research Associates LLC
    • Eunice, Louisiana, United States, 70535
      • Horizon Research Group of Opelousas LLC
    • Gray, Louisiana, United States, 70359
      • Cardiovascular Institute South ASC
    • Hammond, Louisiana, United States, 70403
      • Heart Clinic of Hammond
    • Lafayette, Louisiana, United States, 70503
      • CV Ins of the South
    • Mandeville, Louisiana, United States, 70471
      • Clinical Trials Management LLC
    • Mandeville, Louisiana, United States, 70448
      • North Shore Heart and Vascular
    • Metairie, Louisiana, United States, 70006
      • Omega Clinical Research
    • Monroe, Louisiana, United States, 71201
      • Clinical Trials of America LA LLC
    • Natchitoches, Louisiana, United States, 71457
      • Barnum Medical Research Inc
    • New Orleans, Louisiana, United States, 70115
      • Crescent City Physicians Inc
    • Opelousas, Louisiana, United States, 70570
      • CV Ins of the South
    • Shreveport, Louisiana, United States, 71105
      • Grace Research Llc
    • Slidell, Louisiana, United States, 70458
      • Louisiana Heart Center Research
    • Zachary, Louisiana, United States, 70791
      • Southern Clinical Research
  • Maryland
    • Baltimore, Maryland, United States, 21209
      • Sinai Ct for Throm Res and Drug Dev
    • Beltsville, Maryland, United States, 20705
      • Metropolitan Cardiovascular Consultants LLC
    • Columbia, Maryland, United States, 21044
      • Johns Hopkins University
    • Ft. Washington, Maryland, United States, 20744
      • Anderson Medical Research
    • Glenn Dale, Maryland, United States, 20769
      • Javara Inc
    • Lanham, Maryland, United States, 20706
      • Capitol Cardiology Associates
    • Oxon Hill, Maryland, United States, 20745
      • MD Medical Research
    • Rockville, Maryland, United States, 20850
      • Adventist HealthCare Shady Grove Medical Center
    • Salisbury, Maryland, United States, 21804
      • Tidal Health Peninsula Regional Inc
  • Massachusetts
    • Boston, Massachusetts, United States, 02215
      • Beth Israel Deaconess Medical Center
    • Boston, Massachusetts, United States, 02111
      • Tufts Medical Center
    • Boston, Massachusetts, United States, 02115
      • Dana Farber Cancer Institute
    • Boston, Massachusetts, United States, 02132
      • VA Boston Healthcare System
    • Methuen, Massachusetts, United States, 01844
      • ActivMed Practices and Research
  • Michigan
    • Detroit, Michigan, United States, 48202
      • Henry Ford Hospital
    • Flint, Michigan, United States, 48504
      • AA Medical Research Center
    • Grand Rapids, Michigan, United States, 49546
      • Healthy Heart Cardiology
    • Lansing, Michigan, United States, 48910
      • McLaren Greater Lansing
    • Midland, Michigan, United States, 48670
      • MyMichigan Medical Center Midland
    • Saginaw, Michigan, United States, 48601
      • Central Michigan University
    • Southfield, Michigan, United States, 48075
      • Providence Hospital Patient Care Research
    • Traverse City, Michigan, United States, 49684
      • Traverse Heart and Vascular
    • Ypsilanti, Michigan, United States, 48197
      • Trinity Health Michigan Heart
  • Minnesota
    • Duluth, Minnesota, United States, 55805
      • St Marys Medical Center
    • Minneapolis, Minnesota, United States, 55455
      • University of Minnesota
    • Robbinsdale, Minnesota, United States, 55422
      • North Memorial Heart and Vascular Institute
    • Saint Cloud, Minnesota, United States, 56303
      • CentraCare Heart and Vascular Center
    • Saint Louis Park, Minnesota, United States, 55426
      • Methodist Hospital
    • Saint Paul, Minnesota, United States, 55101
      • Regions Hospital
  • Mississippi
    • Belzoni, Mississippi, United States, 39038
      • Belzoni Clinical Research
    • Jackson, Mississippi, United States, 39216
      • Jackson Heart Clinic
    • Jackson, Mississippi, United States, 39216
      • VAMC Research-G V Sonny Montgomery Clinic
    • Tupelo, Mississippi, United States, 38801
      • Cardiology Associates of North MS
    • Yazoo City, Mississippi, United States, 39194
      • Yazoo Clinical Research
    • Yazoo City, Mississippi, United States, 39194
      • Yazoo Clinical Research .
  • Missouri
    • Kansas City, Missouri, United States, 64128
      • Kansas City VA Medical Center
    • North Kansas City, Missouri, United States, 64116
      • North Kansas City Hospital
    • Springfield, Missouri, United States, 65804
      • Mercy Hospital
    • St Louis, Missouri, United States, 63128
      • Mercy South
    • St Louis, Missouri, United States, 63125-4181
      • St Louis V A Medical Center
    • St Louis, Missouri, United States, 63128
      • Gateway Cardiovascular Rsch Ctr Inc
    • St Louis, Missouri, United States, 63136
      • St Louis Heart and Vascular
  • Nebraska
    • Lincoln, Nebraska, United States, 68516
      • Physician Research Collaboration
    • Omaha, Nebraska, United States, 68130
      • CCT Research
    • Omaha, Nebraska, United States, 68105
      • VA Med NWI Endocrine Studies R151
  • Nevada
    • Henderson, Nevada, United States, 89074
      • Las Vegas Endocrinology
    • Las Vegas, Nevada, United States, 89119
      • AB Clinical Trials
    • Las Vegas, Nevada, United States, 89121
      • Clinical Research of South Nevada
  • New Hampshire
    • Manchester, New Hampshire, United States, 03062
      • Catholic Medical Center
  • New Jersey
    • Haddon Heights, New Jersey, United States, 08035
      • Cooper University Health Care
    • Linden, New Jersey, United States, 07036
      • New Jersey Heart
    • Manalapan, New Jersey, United States, 07726
      • Garden State Heart Care
    • New Brunswick, New Jersey, United States, 08901
      • Robert Wood Johnson Medical School
    • Newark, New Jersey, United States, 07112
      • Newark Beth Israel Medical Center
    • Ridgewood, New Jersey, United States, 07450
      • The Valley Hospital
    • Somerset, New Jersey, United States, 08873
      • Cardio Metabolic Institute
  • New Mexico
    • Albuquerque, New Mexico, United States, 87102
      • New Mexico Heart Institute
  • New York
    • Albany, New York, United States, 12206
      • Albany Medical College
    • Binghamton, New York, United States, 13901
      • Meridian Clinical Research
    • Cooperstown, New York, United States, 13326
      • Bassett Medical Center
    • Endwell, New York, United States, 13760
      • Meridian Clinical Research LLC
    • Mineola, New York, United States, 11501
      • NYU Langone Hlth Card Assoc
    • New York, New York, United States, 10021
      • Weill Cornell Medical Center
    • New York, New York, United States, 10029
      • Icahn School of Med at Mt Sinai
    • Northport, New York, United States, 11768
      • Northport VA Medical Center
    • Rochester, New York, United States, 14609
      • Rochester Clinical Research
    • Stony Brook, New York, United States, 11794-3362
      • State Uni of NY at Stony Brook
    • Valhalla, New York, United States, 10595
      • Westchester Medical Center
  • North Carolina
    • Charlotte, North Carolina, United States, 28277
      • Tryon Medical Partners PLLC
    • Charlotte, North Carolina, United States, 28204
      • Novant Health Heart Vas Inst
    • Morehead City, North Carolina, United States, 28557
      • Lucas Research
    • Raleigh, North Carolina, United States, 27607
      • NC Heart and Vascular Research LLC
    • Salisbury, North Carolina, United States, 28144
      • Accellacare of Salisbury
    • Winston-Salem, North Carolina, United States, 27157
      • Wake Forest University Baptist Medical Center
  • North Dakota
    • Grand Forks, North Dakota, United States, 58201
      • Altru Health Research Dept.
  • Ohio
    • Akron, Ohio, United States, 44309
      • Akron Hospital Summa Health System
    • Cincinnati, Ohio, United States, 45267
      • University of Cincinnati
    • Cincinnati, Ohio, United States, 45246
      • Velocity Clin Research Springdale
    • Cleveland, Ohio, United States, 44106-5028
      • Univ Hosp Cleveland Medical Center
    • Dayton, Ohio, United States, 45414
      • Premier Cardiovascular Institute
    • Kettering, Ohio, United States, 45429
      • Kettering Medical Center
    • Marion, Ohio, United States, 43302
      • Rama Research LLC
    • Springfield, Ohio, United States, 45504
      • Heart House Research Foundation
    • Toledo, Ohio, United States, 43608
      • Mercy Health St Vincent Med Ctr
  • Oklahoma
    • Tulsa, Oklahoma, United States, 74133
      • Oklahoma Heart Institute
  • Oregon
    • Bend, Oregon, United States, 97701
      • Bend Memorial Clinic
    • Corvallis, Oregon, United States, 97330
      • Samaritan Cardiology
  • Pennsylvania
    • Abington, Pennsylvania, United States, 19001
      • Abington Memorial Hospital
    • Butler, Pennsylvania, United States, 16001
      • Independence Health System Cardiovascular Consultants
    • Pittsburgh, Pennsylvania, United States, 15213
      • UPMC
    • Pittsburgh, Pennsylvania, United States, 15236
      • Preferred Primary Care Physicians
    • Pittsburgh, Pennsylvania, United States, 15243
      • Preferred Primary Care Physicians
    • Smithfield, Pennsylvania, United States, 15478
      • Frontier Clinical Research LLC
  • Rhode Island
    • Warwick, Rhode Island, United States, 02886
      • Kent County Memorial Hospital
  • South Carolina
    • Charleston, South Carolina, United States, 29425
      • Medical Univ Of South Carolina
    • Columbia, South Carolina, United States, 29203
      • Columbia Heart Clinic
    • Columbia, South Carolina, United States, 29209
      • Columbia VA Health Care System
    • Greenville, South Carolina, United States, 29615
      • Prisma Health Upstate
    • Greenville, South Carolina, United States, 29607
      • Bon Secours Medical Group
    • Ladson, South Carolina, United States, 29465
      • Trident Cardiology
    • Myrtle Beach, South Carolina, United States, 29588
      • Family Medicine of Sayebrook
  • South Dakota
    • Sioux Falls, South Dakota, United States, 57104
      • Sanford USD Medical Center
    • Sioux Falls, South Dakota, United States, 57105
      • North Central Heart
  • Tennessee
    • Greenville, Tennessee, United States, 37745
      • Wellmont CVA Heart Institute
    • Jackson, Tennessee, United States, 38301
      • The Jackson Clinic PA
    • Jackson, Tennessee, United States, 38301
      • Apex Cardiology Research Associates of Jackson
    • Knoxville, Tennessee, United States, 37934
      • Turkey Creek Medical Center
    • Knoxville, Tennessee, United States, 37938
      • Accellacare
    • Memphis, Tennessee, United States, 38119
      • Memphis Cardiology and Vein Ct
    • Powell, Tennessee, United States, 37849
      • Cardiovascular Res of Knoxville LLC
    • Tullahoma, Tennessee, United States, 37388
      • Tennessee Center for Clinical Trials
  • Texas
    • Amarillo, Texas, United States, 79106
      • PharmaTex Research LLC
    • Bedford, Texas, United States, 76021
      • North Hills Medical Research Inc
    • Conroe, Texas, United States, 77384
      • Javara Research
    • Dallas, Texas, United States, 75216
      • VA North Texas Health Care System
    • Dallas, Texas, United States, 75231
      • North Texas Endocrine Center
    • Dallas, Texas, United States, 75226
      • Soltero Cardiovascular Research Center
    • Dallas, Texas, United States, 75231
      • Texas Health Physicians Group
    • Dallas, Texas, United States, 75235
      • SW Family Medicine Associates
    • Dallas, Texas, United States, 75231
      • Research Institute of Dallas PA
    • Dallas, Texas, United States, 78503
      • Alina Clinical Trials
    • El Paso, Texas, United States, 79905
      • David Turbay MD PLLC
    • Fort Worth, Texas, United States, 76107
      • Texas Health Physicians Group
    • Fort Worth, Texas, United States, 76104
      • Texas Health Physicians Group
    • Houston, Texas, United States, 77030
      • Houston Methodist Hospital
    • Houston, Texas, United States, 77034
      • Orion Medical
    • Houston, Texas, United States, 77030
      • UT Physicians Memorial Hermann
    • Houston, Texas, United States, 77084
      • Village Medical Village MD S Tx
    • Lampasas, Texas, United States, 76550
      • FMC Science
    • Livingston, Texas, United States, 77351
      • East Texas Research Associates Inc.
    • McKinney, Texas, United States, 75071
      • CardioVoyage LLC
    • Pflugerville, Texas, United States, 78660-3015
      • Discovery Clinical Trials
    • Plano, Texas, United States, 75075
      • Heartplace-Plano
    • San Antonio, Texas, United States, 78240
      • Endeavor Clinical Trials
    • San Antonio, Texas, United States, 78229
      • South Texas Cardiovascular Consultants PLLC
    • San Antonio, Texas, United States, 78229-3900
      • University of Texas Health Science Ctr
    • Sherman, Texas, United States, 75090
      • Sherman Clinical Research
    • Stephenville, Texas, United States, 76401
      • Javara Research
    • Sugarland, Texas, United States, 77478
      • Privia Medical Group Gulf Coast
  • Utah
    • Bountiful, Utah, United States, 84010
      • Progressive Clinical Research
  • Virginia
    • Burke, Virginia, United States, 22015
      • Burke Internal Medicine and Research
    • Forest, Virginia, United States, 24551
      • Javara Research
    • Hopewell, Virginia, United States, 23860
      • Heart Care Associates P C
    • Norfolk, Virginia, United States, 23504
      • York Clinical Research
    • Richmond, Virginia, United States, 23219
      • Dominion Medical Associates
    • Roanoke, Virginia, United States, 24014
      • Roanoke Heart Institute
    • Winchester, Virginia, United States, 22601
      • Winchester Medical Center
  • Washington
    • Seattle, Washington, United States, 98195
      • University of Washington
    • Seattle, Washington, United States, 98101
      • Virginia Mason Medical Centre
    • Seattle, Washington, United States, 98122
      • Swedish Medical Center-Cardiovascular Research
    • Tacoma, Washington, United States, 98405
      • Universal Research Group LLC
    • Wenatchee, Washington, United States, 98801
      • Confluence Health Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 40 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

1. Fasting LDL-C ≥ 70 mg/dL at randomization visit
2. Stable (greater than or equal to 4 weeks) and well-tolerated lipid-lowering regimen (including e.g. with or without Ezetimibe) that must include a high-intensity statin therapy with either atorvastatin greater than or equal to 40 mg QD or rosuvastatin greater than or equal to 20 mg QD

3. Established CV disease defined as ANY of the following three conditions

   1. Spontaneous Myocardial infarction ≥ 4 weeks from screening visit
   2. History of ischemic stroke occurred ≥ 4 weeks prior to the Screening visit
   3. Symptomatic peripheral arterial disease (PAD) evidenced by either intermittent claudication with ankle brachial index (ABI) < 0.85, prior peripheral arterial revascularization procedure, or, amputation due to atherosclerotic disease.

Exclusion Criteria:

1. Acute coronary syndrome, stroke, peripheral arterial revascularization procedure or amputation due to atherosclerotic disease < 4 weeks before screening visit
2. Treatment with PCSK9 inhibitors (e.g. evolocumab, alirocumab) within 90 days or planned use post first study visit
3. Planned or expected cardiac, cerebrovascular or peripheral artery surgery or re-vascularization within the 6 months after the first study visit
4. Heart failure NYHA class III or IV
5. Active liver disease defined as any known current infectious, neoplastic, or metabolic pathology of the liver
6. Previous exposure to inclisiran or any other non-mAb PCSK9-targeted therapy, either as an investigational or marketed drug within 2 years
7. Severe concomitant non-CV disease that is expected to reduce life expectancy to less than 5 years
8. History of malignancy that required surgery radiation therapy and/or systemic therapy during the 3 years prior to the first study visit
9. Pregnant or nursing (lactating) women

Other protocol-defined inclusion/exclusion criteria may apply.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Placebo Comparator: Placebo; Subcutaneous injection	Drug: Placebo; Subcutaneously injected on Day 1, Month 3 (Day 90) and every 6 months thereafter until EOS visit
Experimental: Inclisiran sodium; Subcutaneous injection	Drug: Inclisiran sodium 300 mg; Subcutaneously injected on Day 1, Month 3 (Day 90) and every 6 months thereafter until EOS visit

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Time to First Occurrence of 3P-MACE (3-Point Major Adverse Cardiovascular Events)	3P-MACE is a confirmed composite endpoint which includes cardiovascular death, non-fatal myocardial infarction and non-fatal ischemic stroke.	From randomization to total follow-up time (up to 72 months)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Time to Occurrence of Cardiovascular (CV) Death	CV death is defined as death due to cardiovascular events	From randomization to total follow-up time (up to 72 months)
Time to First Occurrence of 4P-MACE (4-Point Major Adverse Cardiovascular Events)	A composite 4P- MACE is defined as CV death, non-fatal MI, non-fatal ischemic stroke and urgent coronary revascularization.	From randomization to total follow-up time (up to 72 months)
Time to occurrence of all-cause death	All-Cause death is defined as: all deaths from randomization until up to 72 months	From randomization to total follow-up time (up to 72 months)
Time to first occurrence of Major Limb Adverse Events (MALE)	Major Limb Adverse Events including acute lower limb ischemia, lower limb amputation due to ischemia, or urgent lower limb revascularization for ischemia	From randomization to total follow-up time (up to 72 months)

Collaborators and Investigators

• Sponsor: Novartis Pharmaceuticals
• Investigators: Study Director: Novartis Pharmaceuticals, Novartis Pharmaceuticals

Study record dates

Study Major Dates

• Study Start (Actual): November 23, 2021
• Primary Completion (Estimated): October 13, 2027
• Study Completion (Estimated): October 13, 2027

Study Registration Dates

• First Submitted: August 17, 2021
• First Submitted That Met QC Criteria: August 25, 2021
• First Posted (Actual): September 1, 2021

Study Record Updates

• Last Update Posted (Actual): May 13, 2026
• Last Update Submitted That Met QC Criteria: May 8, 2026
• Last Verified: May 1, 2026

More Information

Terms related to this study

• Keywords: Dyslipidemia; Hypercholesterolemia; Hyperlipidemia; Inclisiran; siRNA; Atherosclerotic cardiovascular disease; high cholesterol; KJX839
• Additional Relevant MeSH Terms: Vascular Diseases; Cardiovascular Diseases; Metabolic Diseases; Lipid Metabolism Disorders; Arteriosclerosis; Arterial Occlusive Diseases; Nutritional and Metabolic Diseases; Hypercholesterolemia; Dyslipidemias; Atherosclerosis; Hyperlipidemias; Substandard Drugs; Pharmaceutical Preparations; Counterfeit Drugs
• Other Study ID Numbers: CKJX839B12302

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES

IPD Plan Description

Novartis is committed to sharing with qualified external researchers, access to patient-level data and supporting clinical documents from eligible studies. These requests are reviewed and approved by an independent review panel on the basis of scientific merit. All data provided is anonymized to respect the privacy of patients who have participated in the trial in line with applicable laws and regulations.

This trial data availability is according to the criteria and process described on www.clinicalstudydatarequest.com

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: Yes
• Studies a U.S. FDA-regulated device product: No