Skull Bon Variations in Patient with Congenital Unilatral Choanal Atresia
Associated Radiological Variations in the Skull Bones in Patients with Cong: Unilateral Choanal Atresia
Study Overview
Detailed Description
Choanal atresia is a rare congenital disorder caused by a failure to develop the posterior nasal cavity (choana), resulting in a missing opening between the nasopharynx and the nasal cavities.It is the most common congenital anatomical abnormality of the nasal cavities with incidence ratio approximately 1/5000-7000 live births
Generally, choanal atresia may affect one or both Choanae, although most studies show that the unilateral form is more common than the bilateral one,and the incidence is higher in females than in males Children with unilateral choanal atresia are subject to unilateral breathing usually have late unilateral nasal obstruction, persistent ipsilateral rhinorrhea, and recurrent rhinosiusitis Previous studies have shown that the ratio of bone to membranous atresia is 9:1; although a detailed review of CT findings with histopathological studies showed that mixed-wall atresia is the most common and is present in 71% of cases, while in 29% of cases we found a pure bone wall Computer tomography (CT) is presently the golden standard in diagnostics of nasal cavity diseases; thus, it can be applied successfully as a tool for assessing anatomical structures
Study Type
Enrollment (Estimated)
Contacts and Locations
Study Contact
- Name: Ahmed Sayed Moaz, Master
- Phone Number: 0201063390574
- Email: ahmoooodz857@gmail.com
Study Contact Backup
- Name: Mohamed Azam Abdelrazek, Professor
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Sampling Method
Study Population
Description
Inclusion Criteria:
- clinical diagnosis of Congenital Unilateral Choanal Atresia
Exclusion Criteria:
Patients with severe craniofacial syndromes
Study Plan
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Radiological Variations in Skull Bones in Patients with Congenital Unilateral Choanal Atresia: A Cross-Sectional Study"
Time Frame: 10_12 month
|
Degree and Type of Skull Bone Anomalies Presence and extent of bony abnormalities in the skull base (e.g., sphenoid bone asymmetry, pterygoid plate thickening) Degree of nasal cavity narrowing and choanal obstruction Associated maxillofacial bone abnormalities (e.g., septal deviation, maxillary sinus hypoplasia) 2. Measurement of Specific Skull Bone Changes Thickness of the atretic plate (bony vs. membranous) Asymmetry of pterygoid plates (measured in mm) Deviation angle of the nasal septum (in degrees) Orbital and maxillary asymmetry |
10_12 month
|
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Ahmed Ragab Sayed, Lecturer
Publications and helpful links
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- Skull bon in CUCA patient
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
product manufactured in and exported from the U.S.
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