Relation Between Aortic Sclerosis &Severity of Coronary Heart Disease.

May 1, 2025 updated by: Mohamed Aly Mohamed, Sohag University

Relation Between Aortic Valve Sclerosis and Severity of Coronary Heart Disease Assessed by Syntax Score in Sohag University Hospital

the goal of the study to identify the relation between aortic valve sclerosis and severity of coronary heart disease by performing transthoracic echo Doppler study for severity of aortic valve sclerosis in patient will undergo coronary angiography with calculation of syntax score as a tool for severity of coronary heart disease.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

100

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

N/A

Sampling Method

Probability Sample

Study Population

100a patients from both sex who are diagnosed to be aortic valve sclerosis and will undergo coronary angiography in Sohag university hospital

Description

Inclusion Criteria:

  • Aortic sclerosis diagnosed by trans thoracic echo doppler

Exclusion Criteria:

  • patients who known to be Rumatic heart disease or congenital aortic valve disease.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
relation between Aortic valve sclerosis and severity of coronary heart disease
Time Frame: 6 months

significant relation between severity of aortic valve sclerosis assessed by trans thoracic echo doppler quantified by Chandra et al on a scale of 0 to 3.

0 (no involvement).

  1. mild (minor involvement of one leaflet)
  2. moderate (minor involvement of two leaflets or extensive involvement of one leaflet.
  3. severe (extensive involvement of two leaflets or involvement of all three leaflets).

And severity of coronary heart disease in patients already underwent or planned to perform coronary angiography quantified by syntax score considering score above 20 as severe coronary heart disease.
6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sohag University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

May 1, 2025

Primary Completion (Estimated)

November 1, 2025

Study Completion (Estimated)

May 1, 2026

Study Registration Dates

First Submitted

April 24, 2025

First Submitted That Met QC Criteria

May 1, 2025

First Posted (Actual)

May 11, 2025

Study Record Updates

Last Update Posted (Actual)

May 11, 2025

Last Update Submitted That Met QC Criteria

May 1, 2025

Last Verified

May 1, 2025

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Soh-Med-25-4___1MD

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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