Cognitive Impairment and Gait Balance in Chronic Stroke Survivors

Relationship Between Cognitive Impairment and Gait Balance in Chronic Stroke Survivors: A Cross-Sectional Study

This study aims to investigate the relationship between cognitive impairment and gait balance in individuals with chronic stroke. Using the IQCODE and a balance assessment system, the study evaluates how post-stroke cognitive decline may influence stability and motor control. The findings will support better rehabilitation strategies tailored to cognitive function.

Study Overview

• Status: Not yet recruiting
• Conditions: Chronic Stroke Patients

Detailed Description

Cognitive and motor impairments are common consequences of stroke, but they are often treated separately. A growing body of evidence suggests a potential link between cognitive function and physical performance, including balance and gait. This prospective, cross-sectional study investigates the relationship between post-stroke cognitive impairment and gait balance in chronic stroke survivors. Participants will undergo cognitive evaluation using the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), and gait balance will be assessed through center of pressure velocity with eyes open and closed. The goal is to identify whether cognitive decline is associated with impaired balance performance and to explore the influence of age, stroke type, and duration on these outcomes.

• Study Type: Observational
• Enrollment (Estimated): 26

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

A non-random sample of 26 adults aged 25-75 years with chronic stroke, recruited from outpatient rehabilitation centers. Participants were assessed in a single session to evaluate the relationship between cognitive impairment and gait balance.

Description

Inclusion Criteria:

• Adults aged 25-75 years
• Diagnosed with chronic stroke (≥6 months post-stroke)
• Able to stand independently for testing
• Capable of completing assessments or has an informant available for IQCODE

Exclusion Criteria:

• Severe visual, vestibular, or musculoskeletal impairments
• History of other neurological disorders
• Acute illness or uncontrolled medical condition
• Inability to follow instructions or complete cognitive/balance assessments

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Chronic Stroke Survivors; A group of 26 adults with chronic stroke will be assessed to examine the relationship between cognitive impairment and gait balance. Cognitive function will be evaluated using the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), and balance will be assessed using center of pressure measurements with eyes open and closed

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Correlation between IQCODE scores and center of pressure velocity (eyes open)	Assess the relationship between cognitive impairment and balance control by comparing IQCODE scores with center of pressure velocity during quiet standing with eyes open.	At baseline (single session)

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Correlation between IQCODE scores and center of pressure velocity (eyes closed)	Assess the relationship between cognitive impairment and postural control by comparing IQCODE scores with center of pressure velocity during quiet standing with eyes closed.	At baseline (single session)

Collaborators and Investigators

• Sponsor: Islam Hassan Fayed
• Collaborators: Majmaah University

Study record dates

Study Major Dates

• Study Start (Estimated): August 1, 2025
• Primary Completion (Estimated): September 1, 2025
• Study Completion (Estimated): September 1, 2025

Study Registration Dates

• First Submitted: July 14, 2025
• First Submitted That Met QC Criteria: July 14, 2025
• First Posted (Actual): July 22, 2025

Study Record Updates

• Last Update Posted (Actual): July 22, 2025
• Last Update Submitted That Met QC Criteria: July 14, 2025
• Last Verified: July 1, 2025

More Information

Terms related to this study

• Keywords: Cognitive Impairment; Chronic Stroke; Gait Balance
• Additional Relevant MeSH Terms: Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Mental Disorders; Neurocognitive Disorders; Cognition Disorders; Stroke; Cognitive Dysfunction
• Other Study ID Numbers: MUREC-March.17/COM-2021/30-3

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

IPD Plan Description

Your dataset is small, with identifiable clinical information, which raises privacy and ethical concerns.

There's no formal plan in place for anonymized data sharing.

Most ICMJE-compliant journals accept a "No" or "Undecided" answer, especially for observational studies that do not involve public databases.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No