The Acute Effects of Ankle Exercises on Knee Proprioception

September 25, 2025 updated by: Gönül Elpeze, Gaziantep Islam Science and Technology University

The Acute Effects of Ankle Exercises on Knee Proprioception and Pain in Individuals With Knee Pain

The goal of this randomized research study is to investigate the acute effects of ankle exercises on improving knee proprioception and pain in individuals with knee pain, aged 18-70, who receive intervention-based ankle and knee exercises to treat their knee pain. The main question it aims to answer is:

• Does ankle exercise affect knee joint proprioception and pain in individuals with knee pain? Researchers will compare ankle exercise (the intervention) with knee exercise (as part of their regular medical care for knee pain) to determine if ankle exercise is effective in improving knee joint proprioception and reducing pain.

Participants will be asked to do exercises and to let the researchers take their measurements.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

114

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
      • Gaziantep, Turkey (Türkiye)
        • Gaziantep Islam Science and Technology University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • The participants who have a VAS pain score >5,
  • The participants who have experienced knee pain for the last six months or longer,
  • The participants who volunteered to participate in the study

Exclusion Criteria:

  • Individuals who had undergone knee and ankle surgery within the last year
  • Individuals who have a VAS pain score below 5
  • Individuals who are experiencing ROM limitations in the knee or ankle
  • Individuals who have a neurological pathology in the lower extremity

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Knee exercise
Knee flexion-extension
Other: Knee Exercise
The literature emphasizes that long-term and multidirectional exercise programs provide proprioceptive improvements
Other Names:
  • Knee flexion-extension
Experimental: Ankle exercise
Ankle plantar flexion with body weight
Other: Ankle Exercise
In the literature, studies have evaluated ankle proprioception following interventions applied to the knee. However, no studies report the effects of ankle exercises on knee proprioception
Other Names:
  • Plantar flexion

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Knee proprioception
Time Frame: 4 weeks
Knee flexion- extension position
4 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Knee pain
Time Frame: 4 weeks
Visual Analogue Scale (VAS); Zero, no pain; 10 worst pain
4 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Gaziantep Islam Science and Technology University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 6, 2025

Primary Completion (Actual)

May 30, 2025

Study Completion (Actual)

June 20, 2025

Study Registration Dates

First Submitted

September 10, 2025

First Submitted That Met QC Criteria

September 25, 2025

First Posted (Estimated)

September 26, 2025

Study Record Updates

Last Update Posted (Estimated)

September 26, 2025

Last Update Submitted That Met QC Criteria

September 25, 2025

Last Verified

September 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • KNEE PROPRİOCEPTİON

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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