CanCan Body Composition Study (Cancan)

The aim of this study is to develop a dataset with reference body composition measurements using criterion methods. This dataset will be used to develop new protocols to study patients with cancer. Obtaining measurements of sodium bromide (NaBr), deuterium dilution (D2O), and D3-Creatine in a stratified sample of adults will determine the accuracy (and precision) of the available devices for ECW, TBW, and skeletal muscle mass measurements.

Study Overview

• Status: Recruiting
• Conditions: Healthy Participants; Young Healthy Adults; Elderly (People Aged 65 or More)

• Study Type: Observational
• Enrollment (Estimated): 40

Contacts and Locations

• Study Contact: Name: Steven B Heymsfield, MD; Phone Number: 2257632541; Email: steven.heymsfield@pbrc.edu

Study Locations

• United States
  • Louisiana
    • Baton Rouge, Louisiana, United States, 70808
      • Recruiting
      • Pennington Biomedical Research Center
      • Contact: Steven B Heymsfield, MD; Phone Number: 2257632541; Email: steven.heymsfield@pbrc.edu

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

The participants will be community dwelling, have a self-reported ability to walk one-quarter of a mile and climb 10 steps without difficulty, self-reported ability to perform activities of daily living (ADLs) without difficulty, and no life-threatening conditions or diseases that would alter their body composition from what is typical for their age, sex, and BMI. Overall, participants must be ambulatory, able to withstand lying flat on the DXA table for up to 10 minutes, stand without aid for 2 minutes, weigh less than 440 lbs and be in generally good health.

Description

Inclusion Criteria:

• Being either male or female
• Being an adult >20 - <40 or >70 years of age.
• Having a body weight of less than 440 pounds
• Being willing to comply with the study procedures
• Not having a chronic illness (e.g., diabetes, cancer, etc.)
• Must be willing to have biospecimens and imaging stored for research use

Exclusion Criteria:

• Being pregnant, attempting to become pregnant, or breastfeeding
• Having medical implants such as a pacemaker or metal joint replacements
• Having had a mastectomy, breast reduction, or breast implants
• Having hair that cannot fit in a swim cap
• Having a body weight greater than 440 pounds
• Taking medications that alter the body's fluid compartments (ex: diuretics)
• Not willing to have biospecimens and imaging stored for future research use.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Cross-sectional group; 20 young (20-40yo) and 20 older (70+) adults

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Skeletal Muscle Mass	Muscle mass	Single time point

Collaborators and Investigators

• Sponsor: Pennington Biomedical Research Center

Study record dates

Study Major Dates

• Study Start (Actual): October 15, 2025
• Primary Completion (Estimated): April 15, 2026
• Study Completion (Estimated): May 30, 2026

Study Registration Dates

• First Submitted: December 12, 2025
• First Submitted That Met QC Criteria: December 12, 2025
• First Posted (Actual): December 26, 2025

Study Record Updates

• Last Update Posted (Actual): December 26, 2025
• Last Update Submitted That Met QC Criteria: December 12, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Other Study ID Numbers: PBRC 00006218

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No