Comparison of Two Different Dual-Task Training Methods in Patients With Parkinson's Disease

June 6, 2026 updated by: Fatih Söke, Saglik Bilimleri Universitesi

Comparison of Motor-Motor and Cognitive-Motor Dual-Task Training in Patients With Parkinson's Disease

The aim of this study is to compare the effectiveness of motor-motor dual-task training and cognitive-motor dual-task training in patients with Parkinson's disease.The main questions it aims to answer are:

- Whether there is a difference between motor-motor dual-task training and cognitive-motor dual-task training in patients with Parkinson's disease in terms of their effects on motor symptoms, balance, gait, functional mobility, activities of daily living, dual-task activities, cognitive functions, and balance confidence.

Researchers will compare single-task training, motor-motor dual task training and cogvitive-motor dual task training.

Participants will:

  • Receive exercise training at the study clinic twice a week for approximately 45 minutes each time, for 6 weeks.
  • Participate in assessments at the study clinic before and after exercise training.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

39

Phase

  • Not Applicable

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Having been diagnosed with Parkinson's disease by a neurologist according to the UK Brain Bank criteria.
  • Being in stages 1-3 according to the Hoehn-Yahr Scale.

Exclusion Criteria:

  • Presence of a neurological disease other than Parkinson's disease
  • Cognitive impairment (Standardized Mini Mental Test score less than 24)
  • Having undergone deep brain stimulation surgery
  • Having a visual, auditory, or perceptual problem
  • Having any orthopedic, rheumatological, or other condition that may affect walking and balance.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Supportive Care
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Single Task Training
Single task balance and walking training
Other: Single Task Exercise Training
Single task balance and walking exercises. 5-minute warm-up period, followed by 15 minutes of balance exercises and 15 minutes of walking exercises with a 5-minute rest in between, and then a 5-minute cool-down period.
Experimental: Motor-Motor Dual Task Training
Motor-motor dual task balance and walking training
Other: Motor-Motor Dual Task Exercise Training
Motor-motor dual task balance and walking exercises. Motor-motor dual task balance and walking exercises. 5-minute warm-up period, followed by 15 minutes of balance exercises and 15 minutes of walking exercises concurrently performed with upper extremity motor tasks with a 5-minute rest in between, and then a 5-minute cool-down period.
Experimental: Cognitive-Motor Dual Task Training
Cognitive-motor dual task balance and walking training
Other: Cognitive-Motor Dual Task Exercise Training
Cognitive-motor dual task balance and walking exercises. Cognitive-motor dual task balance and walking exercises. 5-minute warm-up period, followed by 15 minutes of balance exercises and 15 minutes of walking exercises concurrently performed with cognitive tasks with a 5-minute rest in between, and then a 5-minute cool-down period.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Unified Parkinson's Disease Rating Scale (UPDRS) - PART 3
Time Frame: From enrollment to the end of training at 6 weeks
UPDRS is a reliable and valid scale that assesses cognitive skills, mood, daily living activities, motor skills, motor fluctuations, dyskinesias and autonomic dysfunction and is widely used in clinical studies and research in Parkinson's disease. The motor symptoms section, which is the third section of this scale, will be used.
From enrollment to the end of training at 6 weeks
Hoehn & Yahr Scale
Time Frame: From enrollment to the end of treatment at 6 weeks
It is a staging system that provides information quickly in determining the severity and symptoms of Parkinson's disease.
From enrollment to the end of treatment at 6 weeks
Single-Leg Stance Test
Time Frame: From enrollment to the end of treatment at 6 weeks
This is a test method used to assess static balance. The patient's preferred foot is raised without touching the supporting leg, and initially, the eyes are open. The eyes are fixed towards the head, and the patient is expected to maintain their balance for 60 seconds. The time the participant maintains their balance is recorded.
From enrollment to the end of treatment at 6 weeks
Functional Reach Test
Time Frame: From enrollment to the end of treatment at 6 weeks
This test is designed to assess dynamic balance. In the test, the participant is positioned sideways next to a wall, with their torso upright, the shoulder on the wall flexed to 90°, and the elbow fully extended. The participant is then asked to make a fist with the same arm, and the position of the third metacarpal head is marked on the wall. The participant reaches forward with their knees fully extended; the position of the third metacarpal head is marked again, and the participant returns to the starting position. The difference between the two marks is measured with a tape measure.
From enrollment to the end of treatment at 6 weeks
10 Meter Walking Test
Time Frame: From enrollment to the end of treatment at 6 weeks
Participants are asked to walk at normal walking speed for a distance of 10 meters and the time is recorded.
From enrollment to the end of treatment at 6 weeks
Motor-Motor Dual Task Cost of Walking
Time Frame: From enrollment to the end of treatment at 6 weeks

To assess the motor-motor dual-task cost of walking, patients will perform the 10-meter walk test once as a single task and once while holding an empty plate on a tray in their hands. The dual-task cost will be calculated as a percentage using the following formula:

[(Dual-task performance - Single-task performance)/ (Single-task performance) x 100]
From enrollment to the end of treatment at 6 weeks
Cognitive-Motor Dual Task Cost of Walking
Time Frame: From enrollment to the end of treatment at 6 weeks

To assess cognitive-motor dual-task cost of walking, patients will perform the 10-Meter Walk Test once as a single task and once as a dual-task test, counting backwards in increments of 7 from a three-digit number greater than 300. Dual-task cost will be calculated as a percentage using the following formula:

[(Dual-task performance - Single-task performance)/ (Single-task performance) x 100]
From enrollment to the end of treatment at 6 weeks
Timed Up and Go Test
Time Frame: From enrollment to the end of treatment at 6 weeks
This test is used to assess functional mobility levels. The test involves using a standard chair with the individual's knees flexed at 90° and their backrest against it. The individual is asked to stand up from the chair, walk 3 meters, turn around, and then walk back to the chair and sit down. The test begins with the command "walk," and the test duration is measured with a stopwatch and recorded in seconds.
From enrollment to the end of treatment at 6 weeks
Unified Parkinson's Disease Rating Scale (UPDRS) - PART 2
Time Frame: From enrollment to the end of treatment at 6 weeks
It consists of thirteen items. The assessment is based on anamnesis information regarding how the patient functions in various activities. The presence of sensory complaints that may be related to tremor and parkinsonism is also included in this section as they can affect daily living activities. Each item is evaluated using a scoring system between '0' and '4'.
From enrollment to the end of treatment at 6 weeks
Dual Task Questionnaire
Time Frame: From enrollment to the end of treatment at 6 weeks
This test is used to assess the challenges encountered in daily tasks involving dual work. It consists of 10 questions and is administered via face-to-face interview. Each question is scored between 0 and 4. A score of "4" indicates frequent challenges, while a score of "0" indicates no challenges.
From enrollment to the end of treatment at 6 weeks
Trail Making Test
Time Frame: From enrollment to the end of treatment at 6 weeks
It is used to assess executive functions and attention. The test consists of two parts, A and B. In part A, the individual is asked to combine numbers from 1 to 25, and the completion time is recorded. In part B, the individual completes a sequence where each number corresponds to a letter, and the completion time is recorded.
From enrollment to the end of treatment at 6 weeks
Activity-Specific Balance Confidence Scale
Time Frame: From enrollment to the end of treatment at 6 weeks
This is a commonly used scale for assessing balance confidence. The scale evaluates whether individuals believe they can perform daily living activities without losing their balance or becoming unsteady. It consists of sixteen items. Each item is scored between a minimum of "0" (unconfident) and a maximum of "100" (completely confident). The base score is calculated by dividing the total score by 16. Higher values indicate that the person feels good about their balance, while lower values are associated with an increased risk of falls.
From enrollment to the end of treatment at 6 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Saglik Bilimleri Universitesi

Collaborators

Eskisehir Osmangazi University
Anadolu University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

June 15, 2026

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

September 15, 2026

Study Registration Dates

First Submitted

June 6, 2026

First Submitted That Met QC Criteria

June 6, 2026

First Posted (Actual)

June 11, 2026

Study Record Updates

Last Update Posted (Actual)

June 11, 2026

Last Update Submitted That Met QC Criteria

June 6, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2026-152

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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