Statewide Optimization of Lung Cancer Screening Utilizing the QUILS™ System in Nevada and Mississippi: State-Based Initiative Component

June 26, 2026 updated by: Timothy Mullett

Statewide Optimization of Lung Cancer Screening Utilizing the QUILS™ System in Nevada and Mississippi: State-Based

This clinical trial studies whether a Quality Implementation of Lung Cancer Screening (QUILS™) System state-based initiative (SBI) intervention works to improve the statewide capacity for implementing and sustaining lung cancer screening in Mississippi (MS) and Nevada (NV). The QUILS™ Group is focused on fair and high-quality implementation of lung cancer screening among eligible individuals to reduce lung cancer-related death in underserved communities. Previous research had success with implementing interventions in Kentucky which has lead to significant increases in lung cancer screening rates and a rapid decline in late-stage lung cancer diagnoses within the state. The goal is to offer the opportunity to replicate this work in states which are eager to address suboptimal screening rates, high lung cancer-related death, and significant health equity concerns. The QUILS™ SBI intervention involves translating the success of the initial work in Kentucky to impact lung cancer screening implementation and lung cancer outcomes in MS and NV through close collaboration with state-based partners. The QUILS™ SBI intervention may be an effective way to improve the statewide capacity for implementing and sustaining lung cancer screening in MS and NV.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

200

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • United States
    • Mississippi
      • Greenville, Mississippi, United States, 38703
      • Greenwood, Mississippi, United States, 38930
        • Recruiting
        • Greenwood Leflore Hospital
        • Contact:
      • Gulfport, Mississippi, United States, 39501
        • Recruiting
        • Memorial Hospital Gulfport
        • Contact:
      • Hattiesburg, Mississippi, United States, 39401
      • Jackson, Mississippi, United States, 39216
        • Recruiting
        • University of Mississippi Medical Center
        • Contact:
      • New Albany, Mississippi, United States, 38652
        • Recruiting
        • Baptist Memorial Hospital
        • Contact:
      • Tupelo, Mississippi, United States, 38801
        • Recruiting
        • North Mississippi Health Services
        • Contact:
    • Nevada
      • Hawthorne, Nevada, United States, 89415
        • Recruiting
        • Mt. Grant General Hospital
        • Contact:
      • Pahrump, Nevada, United States, 89048
      • Reno, Nevada, United States, 89502
        • Recruiting
        • Renown Regional Medical Center
        • Contact:
      • Reno, Nevada, United States, 89511
      • Winchester, Nevada, United States, 89109
      • Winnemucca, Nevada, United States, 89445
        • Recruiting
        • Humboldt General Hospital
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Member of a state-based lung cancer screening implementation team in Mississippi or Nevada.
  • Leadership member of the Mississippi state team or Nevada state team
  • Active member of the Mississippi Lung Cancer Roundtable (MSLCRT) or Nevada Lung Cancer Coalition (NLCC)
  • Willing to participate in study-related assessments an implementation activities

Exclusion Criteria:

  • None

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Screening
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Health Services Research (SBI Intervention)
Participants implement the QUILS™ SBI intervention over 4 years consisting of the following steps: 1) Hire and establish connections with both groups, work with the MSLCRT and NLCC during year 1; 2) Participate in annual meetings hosted by MSCLRT and NLCC during years 1-4; 3) Attend State Team Assessment Feedback Sessions during years 2-4; 4) Attend Coalition Assessment Feedback Sessions during years 2-4; 5) Prioritize objectives, identify areas to support, implementation of state-based initiative, and receive coaching/support during years 2 and 3; 6) Receive coaching and technical assistance to implement priority areas during years 1-4; 7) Participate in sustainability planning during year 4.
Behavioral: QUILS SBI Intervention
Participants implement the QUILS™ SBI intervention over 4 years consisting of the following steps: 1) Hire and establish connections with both groups, work with the MSLCRT and NLCC during year 1; 2) Participate in annual meetings hosted by MSCLRT and NLCC during years 1-4; 3) Attend State Team Assessment Feedback Sessions during years 2-4; 4) Attend Coalition Assessment Feedback Sessions during years 2-4; 5) Prioritize objectives, identify areas to support, implementation of state-based initiative, and receive coaching/support during years 2 and 3; 6) Receive coaching and technical assistance to implement priority areas during years 1-4; 7) Participate in sustainability planning during year 4.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in Statewide Capacity Assessment Scores for Lung Cancer Screening Implementation and Sustainability Capacity
Time Frame: Up to 3 Years
Statewide capacity will be assessed using the State Team Assessment (STA) and Coalition Assessment (CA) instruments. Higher scores indicate greater capacity to implement an sustain lung cancer screening activities.
Up to 3 Years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Timothy Mullett

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 1, 2026

Primary Completion (Estimated)

July 1, 2028

Study Completion (Estimated)

July 1, 2029

Study Registration Dates

First Submitted

June 26, 2026

First Submitted That Met QC Criteria

June 26, 2026

First Posted (Actual)

July 6, 2026

Study Record Updates

Last Update Posted (Actual)

July 6, 2026

Last Update Submitted That Met QC Criteria

June 26, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • MCC-25-KYQUILS-NVMS

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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