Digital Eye Strain in Online Learning and Remote Work Environments: A Systematic Review (DES-OLRW)

Digital Eye Strain in Online Learning and Remote Work Environments: Prevalence, Risk Factors, and Management Strategies-A Systematic Review

This systematic review aims to evaluate the prevalence of digital eye strain (DES) among individuals engaged in online learning and remote work, identify associated demographic, behavioral, environmental, and ocular risk factors, and summarize evidence regarding preventive and therapeutic management strategies. Electronic databases including PubMed/MEDLINE, Scopus, Web of Science, Embase, Cochrane Library, and Google Scholar were systematically searched for relevant studies published from January 2020 onward. Eligible studies included observational and interventional studies involving online learners or remote workers that reported the prevalence, risk factors, or management of DES. Two independent reviewers performed study selection, data extraction, and quality assessment. The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Where appropriate, quantitative synthesis using a random-effects meta-analysis was planned; otherwise, findings were synthesized narratively. The review is intended to provide evidence-based recommendations for reducing the burden of digital eye strain in educational and occupational settings characterized by prolonged digital device use.

Study Overview

• Status: Completed
• Conditions: Computer Vision Syndrome; Digital Eye Strain (DES)
• Intervention / Treatment: Other: Systematic Literature Review

Detailed Description

Digital eye strain (DES), also known as computer vision syndrome, has become an increasingly important public health concern due to the widespread use of digital devices in education and the workplace. The rapid expansion of online learning and remote work, particularly following the COVID-19 pandemic, has substantially increased daily screen exposure among students and employees, leading to a higher prevalence of visual and ocular symptoms.

DES encompasses a range of symptoms including eye fatigue, dryness, burning sensation, blurred vision, headache, diplopia, neck pain, and shoulder discomfort. These symptoms result from multiple interacting factors, including prolonged accommodation, decreased blink rate, tear film instability, poor ergonomics, improper viewing distance, glare, inadequate lighting, and prolonged uninterrupted screen use. The condition may adversely affect quality of life, academic performance, workplace productivity, and overall well-being.

The objective of this systematic review was to synthesize the current evidence regarding the prevalence of digital eye strain among individuals participating in online learning and remote work, identify associated risk factors, and evaluate available preventive and therapeutic management strategies.

The review included observational studies (cross-sectional, cohort, and case-control) and interventional studies involving online learners or remote workers published in English from January 2020 onward. Studies were identified through comprehensive searches of PubMed/MEDLINE, Scopus, Web of Science, Embase, Cochrane Library, and Google Scholar. Two independent reviewers screened titles, abstracts, and full-text articles according to predefined eligibility criteria, extracted study data, and assessed methodological quality using the Joanna Briggs Institute Critical Appraisal Checklists for observational studies and the Cochrane Risk of Bias 2 tool for interventional studies.

Extracted data included study characteristics, participant demographics, sample size, duration of screen exposure, methods used to assess digital eye strain, prevalence estimates, identified risk factors, evaluated interventions, and principal findings. A narrative synthesis summarized the available evidence, while quantitative meta-analysis using a random-effects model was planned when sufficient homogeneous data were available. Statistical heterogeneity was assessed using Cochran's Q test and the I² statistic.

The findings of this review are expected to provide a comprehensive synthesis of the current literature, identify modifiable risk factors, summarize evidence-based preventive and therapeutic approaches, and support recommendations for educational institutions, employers, healthcare professionals, and policy makers aimed at reducing the burden of digital eye strain among digital device users.

• Study Type: Observational
• Enrollment (Actual): 8972

Contacts and Locations

Study Locations

• Egypt
  • Benha
    • Banhā, Benha, Egypt, 13111
      • Benha University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

The study population consists of participants included in published studies evaluating digital eye strain among individuals engaged in online learning or remote work, including school and university students, educators, office employees, and other adults using digital devices for prolonged periods.

Description

Inclusion Criteria:

• Published observational studies (cross-sectional, cohort, or case-control) and interventional studies.
• Studies involving individuals participating in online learning or remote work.
• Studies reporting the prevalence, risk factors, severity, or management of digital eye strain (computer vision syndrome).
• Studies published in English.
• Publications from January 2020 onward.
• Full-text articles available for review.

Exclusion Criteria:

• Case reports and case series.
• Editorials, commentaries, letters, conference abstracts, and narrative reviews.
• Studies unrelated to online learning or remote work.
• Animal or laboratory studies.
• Duplicate publications.
• Studies with insufficient data for extraction.

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Published Studies on Digital Eye Strain; This cohort consists of published observational and interventional studies included in a systematic review evaluating the prevalence, risk factors, and management strategies for digital eye strain among individuals engaged in online learning and remote work.	Other: Systematic Literature Review; Systematic identification, selection, appraisal, and synthesis of published studies evaluating digital eye strain in online learning and remote work environments. No intervention was administered directly to participants.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Proportion of Participants with Digital Eye Strain	To estimate the pooled prevalence of digital eye strain among individuals engaged in online learning and remote work using data extracted from eligible published studies included in the systematic review and meta-analysis.	Baseline

Collaborators and Investigators

• Sponsor: Benha University

Study record dates

Study Major Dates

• Study Start (Actual): February 1, 2025
• Primary Completion (Actual): May 15, 2026
• Study Completion (Actual): June 23, 2026

Study Registration Dates

• First Submitted: July 10, 2026
• First Submitted That Met QC Criteria: July 14, 2026
• First Posted (Actual): July 16, 2026

Study Record Updates

• Last Update Posted (Actual): July 16, 2026
• Last Update Submitted That Met QC Criteria: July 14, 2026
• Last Verified: July 1, 2026

More Information

Terms related to this study

• Keywords: Online Learning; Screen Time; Digital Eye Strain; Computer Vision Syndrome
• Other Study ID Numbers: Ophth_110_2025_DES_SR

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No