Effects Of Optimized Blinking Training on Visual Function and Tear Film Parameters in Individuals With CVS

Effects Of Optimized Blinking Training on Visual Function and Tear Film Parameters in Individuals With Computer Vision Syndrome

"Computer vision syndrome (CVS), refers to a range of eye and vision issues caused by extended use of computers, tablets, e-readers, and smartphones. Computer users experience visual symptoms, such as eyestrain, headaches, eye discomfort, dry eyes, double vision, and blurred vision, especially after long periods of looking at screens, whether up close or at a distance.

Study Overview

• Status: Active, not recruiting
• Conditions: Computer Vision Syndrome
• Intervention / Treatment: Diagnostic test: Grouyp 1 (without blinking exercises).; Combination product: EXP group (Routine CVS treatment)

Detailed Description

Individuals will be randomly assigned to either an experimental group (group A) receiving OBT with routine rehabilitation CVS management 20-20-20 rule, blue light-blocking glasses, and polyvinyl alcohol eye drops or a control group (group B) receiving only routine rehabilitation, including the 20-20-20 rule, blue light-blocking glasses, and polyvinyl alcohol eye drops. OBT consisted of structured blinking exercises performed thrice daily for three months. Objective outcomes, including tear film parameters and visual function using subjective Computer Vision Syndrome Questionnaire (CVS-Q) shall be evaluated. The collected data will be analysed by using SPSS."

• Study Type: Interventional
• Enrollment (Actual): 52
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Pakistan
  • Punjab
    • Kasur, Punjab, Pakistan
      • Ramzan Eye Care and Optix Khudian Khas

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Individuals aged 18-40 years who work on computers or digital devices for at least 3 to 6 hours daily.
• Both Male and Female.
• Individuals who could undergo a complete ocular examination.
• Presence of symptoms consistent with digital eye strain.
• Presented with eye complaints such as eye fatigue, burning, irritation, redness, and blurred vision due to long-term computer or digital screen use.
• Symptoms worsened during exposure to digital screen light.

Exclusion Criteria:

• Use of medications that might influence tear production or ocular surface status (e.g., antihistamines, antidepressants).
• Diagnosed neurological or systemic conditions that impact vision or blink patterns (e.g., Parkinson's disease, multiple sclerosis).
• Individual's with a history of ocular surface diseases such as conjunctivitis or keratitis.
• History of any psychiatric diagnosis."

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Health Services Research
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Grouyp 1 (without blinking exercises).	Diagnostic test: Grouyp 1 (without blinking exercises).; Group B (Control Group) The control group will continue receiving only the routine rehabilitation (without blinking exercises). Routine rehabilitation included the 20-20-20 rule, blue light-blocking glasses, and polyvinyl alcohol eye drops.
Experimental: EXP group (Routine CVS treatment)	Combination product: EXP group (Routine CVS treatment); "Group A (Experimental Group): Individuals in the Experimental group will receive Routine CVS treatment with optimized blinking exercise. Routine rehabilitation includes the 20-20-20 rule, blue light-blocking glasses, and polyvinyl eye drops. The blinking exercise involved the individuals looking at an object 6 meters away for 5 seconds, followed by complete eyelid closure for 5 seconds. This cycle was repeated for 5 minutes, twice a day."

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Computer Vision Syndrome (CVS-Q)	The Computer Vision Syndrome Questionnaire (CVS-Q) assesses the frequency and intensity of 16 ocular and visual symptoms related to prolonged screen use, with a total score of 6 or more indicating CVS If the total score is ≥6 points, the individual is considered to suffer Computer Vision Syndrome	12 Months

Collaborators and Investigators

• Sponsor: Superior University

Study record dates

Study Major Dates

• Study Start (Actual): March 20, 2025
• Primary Completion (Estimated): June 20, 2025
• Study Completion (Estimated): February 20, 2026

Study Registration Dates

• First Submitted: March 29, 2025
• First Submitted That Met QC Criteria: March 29, 2025
• First Posted (Actual): April 6, 2025

Study Record Updates

• Last Update Posted (Actual): April 6, 2025
• Last Update Submitted That Met QC Criteria: March 29, 2025
• Last Verified: March 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Disease; Syndrome
• Other Study ID Numbers: MSRSW/Batch-Fall23/810

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No