Patterns of CAKUT in Children at Sohag University Hospital (CAKUT - SUH)

Patterns of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Among Children Admitted to Sohag University Hospital

This is an observational study conducted at Sohag University Hospital to assess the clinical presentation, associated anomalies, and short-term outcomes of children diagnosed with Congenital Anomalies of the Kidney and Urinary Tract (CAKUT).

We will include children from newborns to 18 years old who are diagnosed with CAKUT by ultrasound or other imaging methods. The study aims to describe how common different types of CAKUT are, what other health problems are associated with them, and what happens to these children during follow-up.

No experimental drugs or interventions will be given. We will only collect data from patient medical records and routine follow-up visits.

The results of this study will help doctors in Egypt better understand CAKUT and improve early diagnosis and management for children

Study Overview

• Status: Not yet recruiting
• Conditions: CAKUT; Congenital Kidney Disease; Congenital Anomalies of the Kidney and Urinary Tract
• Intervention / Treatment: Other: Observational follow-up

Detailed Description

This is a single-center, observational cohort study conducted at the Pediatric Nephrology Department, Sohag University Hospital, Egypt.

Study Population: Children from birth to 18 years diagnosed with Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) by prenatal or postnatal ultrasound or other imaging modalities.

Data Collection: Demographic data, clinical presentation, laboratory results, imaging findings, and treatment modalities will be collected from medical records. Patients will be followed during routine clinic visits for a minimum of 6 months.

Objectives:

1. To determine the frequency and types of CAKUT in our center.
2. To describe associated extra-renal anomalies.
3. To assess short-term renal outcomes and complications.

This study does not involve any experimental interventions. All investigations and management will be according to standard hospital protocols.

• Study Type: Observational
• Enrollment (Estimated): 100

Contacts and Locations

• Study Contact: Name: Marina Abd El-Malak Ibrahim, M.B.B. Ch; Phone Number: 01204779964; Email: marina.abdelmalaak@med.sohag.edu.eg

Study Locations

• Egypt
  • Sohag Governorate
    • Sohag, Sohag Governorate, Egypt, 82511
      • Sohag University Hospital
      • Contact: Marina Abd El-Malak Ibrahim, M.B.B. Ch; Phone Number: 01204779964; Email: marina.abdelmalaak@med.sohag.edu.eg
      • Principal Investigator: Marina Abd El-Malak Ibrahim, M.B.B. Ch

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Pediatric patients aged 0-18 years with a diagnosis of CAKUT who are followed at the Pediatric Nephrology Department, Sohag University Hospital, Egypt.

Description

Inclusion Criteria:

• All children admitted to Pediatric department, Sohag University Hospital who had a renal ultrasound performed.

Exclusion Criteria:

1. Files with missing essential data.
2. Children transferred from another hospital without renal US done at our center.
3. Children who died before renal US could be performed.
4. Age > 18 years
5. Acquired kidney disease not related to congenital anomalies
6. Patient/family refusal to participate

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
CAKUT Patients; Children from birth to 18 years old diagnosed with Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) who are followed at Sohag University Hospital.	Other: Observational follow-up; No experimental intervention. Data will be collected from routine clinical care, medical records, and follow-up visits according to standard hospital protocols.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Frequency and Types of CAKUT	The proportion of different types of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) diagnosed by ultrasound among pediatric patients at Sohag University Hospital.	1 Year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Associated Extra- renal Anomalies	Frequency of associated congenital anomalies in other organ systems in children with CAKUT.	1 Year
Renal Outcome	Incidence of CKD, hypertension, or need for dialysis/transplant during follow-up period.	1 Year

Collaborators and Investigators

• Sponsor: Marina abd El-Malak Ibrahim

Publications and helpful links

Helpful Links

• Sohag University Hospital - Department of Pediatrics

Study record dates

Study Major Dates

• Study Start (Estimated): August 1, 2026
• Primary Completion (Estimated): January 1, 2027
• Study Completion (Estimated): February 1, 2027

Study Registration Dates

• First Submitted: July 22, 2026
• First Submitted That Met QC Criteria: July 22, 2026
• First Posted (Actual): July 27, 2026

Study Record Updates

• Last Update Posted (Actual): July 27, 2026
• Last Update Submitted That Met QC Criteria: July 22, 2026
• Last Verified: July 1, 2026

More Information

Terms related to this study

• Keywords: Children; Egypt; CAKUT; Sohag; Congenital anomalies of the kidney; Urinary Tract Anomalies; Pediatric Nephrology; Congenital kidney disease
• Additional Relevant MeSH Terms: Cakut
• Other Study ID Numbers: Soh-Med-26-7-28MS

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: Individual participant data will not be shared due to patient privacy and data protection policies at Sohag University Hospital.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No