Cluster Training With Blood Flow Restriction in Competitive 200-m Freestyle Swimmers (BFR-CLUSTER-SW)

August 24, 2026 updated by: Saif Rasheed Ghanim

Cluster Training With Blood Flow Restriction and 200-m Freestyle Performance, FGF-2, and VEGF-A Responses in Competitive Swimmers: A Matched Controlled Study

This study evaluated whether adding blood flow restriction (BFR) to cluster-based training could improve swimming performance and selected physiological responses in competitive swimmers. Twenty competitive swimmers were assigned using a matched, non-randomized design to either an experimental group performing cluster training combined with BFR or a control group performing the same cluster training without BFR. The intervention lasted 8 weeks, with five training sessions per week. The primary outcome was 200-m freestyle performance time. Secondary outcomes included serum concentrations of fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor-A (VEGF-A), standing long jump performance, mean 50-m split time during a 150-m swimming test, and repetitions completed during a cadence-controlled Burpee test. The study was designed to determine whether BFR provided additional performance and physiological benefits beyond cluster training alone.

Study Overview

Detailed Description

Blood flow restriction (BFR) training is a training method in which pneumatic cuffs are applied proximally to the limbs to partially restrict vascular flow during exercise. Cluster training divides traditional exercise sets into smaller clusters of repetitions separated by short intra-set recovery periods. Combining these two approaches may increase the physiological stimulus of training while allowing repeated high-quality exercise efforts.

This controlled, non-randomized matched-intervention study included 20 competitive 200-m freestyle swimmers. Participants were matched according to baseline 200-m freestyle performance, sex, and standing long jump distance and were assigned to one of two groups. The experimental group completed cluster training combined with BFR, whereas the control group completed cluster training without BFR.

The training intervention lasted 8 weeks and consisted of five 90-minute training sessions per week. Sessions included a standardized warm-up, a main training component, and a cool-down. Overall cardiovascular training intensity was prescribed relative to individual maximal heart rate, and cluster-based resistance exercises incorporated short intra-set recovery intervals.

BFR was applied only in the experimental group during selected dry-land cluster exercises using pneumatic cuffs positioned proximally on the upper arms and thighs. The cuffs remained inflated during exercise execution and short intra-set recovery periods and were deflated during the main inter-set recovery periods.

The primary outcome was change in 200-m freestyle performance time from baseline to the end of the 8-week intervention. Secondary outcomes included serum FGF-2 and VEGF-A concentrations, standing long jump distance, mean 50-m split time during a maximal 150-m swimming test, and performance in a cadence-controlled Burpee test. Blood samples were collected under standardized resting conditions to assess serum FGF-2 and VEGF-A concentrations.

The main objective was to determine whether the addition of BFR to cluster training was associated with greater improvements in swimming performance, selected physical-performance outcomes, and serum angiogenesis-related biomarkers compared with cluster training alone.

Study Type

Interventional

Enrollment (Actual)

20

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • Muhafazat Salah ad Din
      • Samarra, Muhafazat Salah ad Din, Iraq, 34010
        • Samarra Olympic Swimming Pool

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

Competitive 200-m freestyle swimmers aged 17-20 years. At least 2 years of structured swimming training experience. Free from musculoskeletal injury for at least 6 months before enrollment. No previous regular experience with blood flow restriction training. Willing and able to complete the 8-week training intervention and all study assessments.

Exclusion Criteria:

History of cardiovascular, metabolic, thrombotic, or other vascular conditions that could contraindicate blood flow restriction exercise.

Current use of medications known to affect vascular tone or blood coagulation. Musculoskeletal injury or medical condition preventing participation in maximal swimming or dry-land training.

Attendance below 85% of the scheduled intervention sessions.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Other
  • Allocation: Non-Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Cluster Training With Blood Flow Restriction
Participants in this arm completed an 8-week cluster-training program combined with blood flow restriction (BFR). Training was performed five sessions per week. Pneumatic cuffs were applied proximally to the upper arms and thighs during selected dry-land cluster exercises and intra-set recovery periods, and were deflated during the main inter-set recovery periods.
An 8-week cluster-training program performed five sessions per week, with blood flow restriction applied during selected dry-land cluster exercises using pneumatic cuffs positioned proximally on the upper arms and thighs.
Active Comparator: Cluster Training Alone
Participants in this arm completed the same 8-week cluster-training program and overall training schedule as the experimental group, but without blood flow restriction. Training was performed five sessions per week.
An 8-week cluster-training program performed five sessions per week without blood flow restriction.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Change in 200-m Freestyle Performance Time
Time Frame: Baseline and post-intervention at 8 weeks
Performance was assessed during a maximal 200-m freestyle swim in a standard 50-m pool using an electronic timing system with a precision of 0.01 s. Lower values indicate faster performance. The primary outcome was the change in performance time from baseline to the end of the 8-week intervention.
Baseline and post-intervention at 8 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 15, 2026

Primary Completion (Actual)

March 19, 2026

Study Completion (Actual)

June 15, 2026

Study Registration Dates

First Submitted

August 21, 2026

First Submitted That Met QC Criteria

August 21, 2026

First Posted (Actual)

August 25, 2026

Study Record Updates

Last Update Posted (Actual)

August 26, 2026

Last Update Submitted That Met QC Criteria

August 24, 2026

Last Verified

August 1, 2026

More Information

Terms related to this study

Other Study ID Numbers

  • SRG-BFR-SWIM-2026-01

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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