Gyrotonic Exercise in Lupus Adolescents Who Survived From Intensive Care

lupus adoelscented who recently survive from intenive care unit usually complain postintenive care unit syndrome in addition to stress, fatigue, low life quality, depression, low physical performance, low grip strenght, insomnia, weak cariorepsiratory fitness, and low physical capcity. gryotonic exercise may improve these problems

Study Overview

• Status: Recruiting
• Conditions: Post Intensive Care Unit Syndrome; Adolescents; Systemic Lupus Erthematosus; Intensive Care Unit Survivors; Childhood-onset Systemic Lupus Erythematous
• Intervention / Treatment: Behavioral: Gryotonic exercise

Detailed Description

forty lupus adoelscented who recently survive from intenive care unit will be divided to 8-week gryotonic exercise group (20 patients) and waitlist group who contained the same number (20 patients)

• Study Type: Interventional
• Enrollment (Estimated): 40
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Ali MA Ismail, PhD; Phone Number: +201005154209; Email: ali.mohamed@pt.cu.edu.eg
• Study Contact Backup: Name: Fatma M mohamed, PhD; Phone Number: +201033321109; Email: fatmaraed1994@gmail.com

Study Locations

• Egypt
  • Giza Governorate
    • Dokki, Giza Governorate, Egypt, 11432
      • Recruiting
      • Cairo University
      • Contact: ali AM Ismail, lecturer; Phone Number: +201005154209; Email: ali.mohamed@pt.cu.edu.eg

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 13 years to 17 years (Child)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Female

Description

Inclusion Criteria:

• childhood-onset lupus
• adolescents who survived from intensive care unit
• adlescents who are in risk of developing pos-tintenive care-unit syndrome (i.e patients who admitted to an intenive care unit for at least four days in last year)

Exclusion Criteria:

• mental diseases
• upper or lower limb fractures

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: group I; twenty lupus adoelscented who recently survive from intenive care unit will be perform 8-week gryotonic exercise	Behavioral: Gryotonic exercise; twenty lupus adoelscented who recently survive from intenive care unit will be perform 8-week gryotonic exercise
No Intervention: group II; twenty lupus adoelscented who recently survive from intenive care unit will be act as waitlist group for 8 weeks

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
total score of post-intensive care-syndrome questioanire-related subscales	the total score post-intensive care-syndrome questionaire-related subscales (cognitive, physical, and mental) will be assessed	it will be assessed after 8 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
patient health questionnaire	it is a questionnaire for depression assessment	it will be assessed after 8 weeks
stress vuilnerability scale	it is a questionaire assesing stress level	it will be assessed after 8 weeks
physical score of child health questionaire	the parent form of this queationaire will assess physical summary level of participants	it will be assessed after 8 weeks
Child health questionaire -mental summary	the parent form of this queationaire will assess mental summary level of participants	it will be assessed after 8 weeks
lupus-related life quality (physical health domain)	A questionaire will assess lupus-related physical health	it will be assessed after 8 weeks
lupus-related life quality (fatigue domain)	a questionaire that will assess lupus-related fatigue	it will be assessed after 8 weeks
Pitsburrg sleeping quality index	the total score of this questionaire that measures sleep quality will be evalauted	it will be assessed after 8 weeks
six minute walk distance	it will assess physcial capacity	it wil be assessed after 8 weeks
Ruffier index	it is and index that will measure cardiorespiratory fittness	it will be assessed after 8 weeks
grip stenght	it will be assessed for dominant hand	it will be assessed after 8 weeks
Short Physical Performance Battery	it is assessment for phsyical performance of patients	It will be assessed after 8 weeks
mental subscale of post-intensive care-syndrome questioanire	the mental subscale of post-intensive care-syndrome questionaire will be assessed	It will be measured after 8 weeks
cognitive subscale of post-intensive care-syndrome questioanire	the cogniitve subscale of post-intensive care-syndrome questionaire will be assessed	It will be measured after 8 weeks
Physcial subscale of post-intensive care-syndrome questionaire	the physical subscale of post-intensive care-syndrome questionaire will be assessed	It will be measured after 8 weeks

Collaborators and Investigators

• Sponsor: Cairo University
• Investigators: Principal Investigator: Ali MA Ismail, lecturer, Department of Physical Therapy for Cardiovascular/Respiratory Disorder and Geriatrics

Study record dates

Study Major Dates

• Study Start (Actual): August 11, 2026
• Primary Completion (Estimated): November 30, 2026
• Study Completion (Estimated): November 30, 2026

Study Registration Dates

• First Submitted: September 16, 2026
• First Submitted That Met QC Criteria: September 16, 2026
• First Posted (Actual): September 22, 2026

Study Record Updates

• Last Update Posted (Actual): September 22, 2026
• Last Update Submitted That Met QC Criteria: September 16, 2026
• Last Verified: September 1, 2026

More Information

Terms related to this study

• Other Study ID Numbers: IRB000-14233-100

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No