Search clinical trials for: decrease of sedation doses and switch of ventilator settings

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Eisai Inc.

Completed

Efficacy and Safety of Oral E5501 Plus Standard of Care for the Treatment of Thrombocytopenia in Adults With Chronic Immune Thrombocytopenia (Amendment 02)

Immune Thrombocytopenia | Chronic Thrombocytopenia

Poland, Ukraine, Belgium, Bulgaria, South Africa, Netherlands, New Zealand, Singapore, Australia, Slovakia, Czechia
Bayer

Completed

Phase 1 Study of PI3 (Phosphatidylinositol-3)-Kinase Inhibitor Copanlisib With Gemcitabine or Cisplatin Plus Gemcitabine in Patients With Advanced Cancer

Neoplasms

United States
Jiangsu Simcere Pharmaceutical Co., Ltd.

Unknown

The Comparative Study on Rh-Endostatin (Endostar®) Continuous Intravenous Infusion and Routine i.v in Combination With GP Regimens for Phase III B/IV Squamous Cell Lung Cancer and Biological Markers Exploration.

Lung Cancer

China
Nitric BioTherapeutics, Inc

Terminated

Safety and Efficacy of Gaseous Nitric Oxide on Venous Stasis Leg Ulcers

Venous Ulcers

United States
RedHill Biopharma Limited

Completed

Open Label Efficacy and Safety of Anti-MAP (Mycobacterium Avium Ssp. Paratuberculosis) Therapy in Adult Crohn's Disease (MAPUS2)

Crohn Disease

United States, Canada, Czechia, Israel, New Zealand, Poland, Serbia
Aristotle University Of Thessaloniki

Completed

24-hour Study of Dorzolamide/Timolol and Latanoprost/Timolol Fixed Combinations

Open-angle Glaucoma

Greece
The University of Hong Kong

Completed

Myfortic® for Minimal Change Nephrotic Syndrome (MCNS): a Randomized Study

Nephrosis, Lipoid

China
University Medical Center Groningen

Completed

Relapse Myeloma; Cyclofosfamide; Bortezomib; Maintenance (REMM)

Multiple Myeloma

Netherlands
Boehringer Ingelheim

Completed

Bioavailability of Telmisartan/Amlodipine Fixed-dose Combination Compared to Its Mono-components in Healthy Male Volunteers

Healthy
david andrews

Completed

Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma

Neoplasms | Malignant Glioma

United States
Zhejiang Hisun Pharmaceutical Co. Ltd.

Unknown

Efficacy and Safety of HS-25 or in Combination With Atorvastatin in Chinese Adults With Primary Hypercholesterolemia (HS-25-C-01)

Primary Hypercholesterolemia
U.S. Army Medical Research and Development Command
GlaxoSmithKline; Walter Reed Army Institute of Research (WRAIR)

Completed

A Two-dose Primary Vaccination Study of a Tetravalent Dengue Virus Purified Inactivated Vaccine vs. Placebo in Healthy Adults (in Puerto Rico) (DPIV-002)

Dengue Fever

Puerto Rico
Citius Pharmaceuticals, Inc.
Therapeutics, Inc.

Completed

Safety and Efficacy of CITI-002 in Adult Patients With Moderate Grade Hemorrhoids

Hemorrhoids

United States
Cairo University
Ahmed Elgazzar Hospital

Completed

Low-molecular-weight Heparin (LMWH) Versus Unfractionated Heparin (UFH) in Pregnant Women With Recurrent Abortion Secondary to Antiphospholipid Syndrome

Recurrent Abortion

Egypt
Novartis Pharmaceuticals

Completed

Evaluation of Early Conversion to Everolimus From Cyclosporine in de Novo Renal Transplant Recipients

Renal Function

Denmark, Norway, Sweden
University of Oulu

Completed

Achilles Tendon Rupture, Conservative vs. Operative Treatment: Prospective Randomized Controlled Trial

Achilles Tendon Rupture

Finland
Oslo University Hospital
University Hospital of North Norway; Helse Stavanger HF; Haukeland University... and other collaborators

Recruiting

The Relapse from MRD Negativity As Indication for Treatment (REMNANT) Study

Multiple Myeloma

Norway
Rajiv Gandhi Cancer Institute & Research Center...

Completed

To Study the Effect of Sevoflurane and Propofol V Sevoflurane and Dexmedetomidine on Postoperative Cognitive Dysfunction (POCD)

Postoperative Cognitive Dysfunction

India
Zagazig University

Recruiting

Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy; A Randomized Controlled Clinical Trial

Different Methods to Minimize Blood Loss During Laparoscopic Myomectomy

Egypt
Uskudar State Hospital
Basaksehir Cam & Sakura Şehir Hospital

Not yet recruiting

The Relationship of Multifidus and Gastrocnemius Muscle Thickness With Postural Stability in Patients With Stroke

Stroke | Postural; Defect | Hemiplegia
Cancer Institute and Hospital, Chinese Academy...

Unknown

Phase II Study of Preoperative IMRT Combined With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer

Locally Advanced Malignant Neoplasm

China
Wuhan Union Hospital, China

Not yet recruiting

A Clinical Study Evaluating the Dermal Safety of Soluble Denosumab Microneedle Patches (CSEDSSDMP)

Healthy | Osteoarthritis | Osteoporosis | Osteoporosis (Senile) | Osteoarthritis (OA) of the Knee

China
Fred Hutchinson Cancer Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

MsFLASH-03: Comparative Efficacy of Low-Dose Estradiol and Venlafaxine XR for Treatment of Menopausal Symptoms

Hot Flashes | Menopause | Vasomotor Disturbance

United States
National Taiwan University Hospital
Mackay Memorial Hospital; Kaohsiung Medical University; Tri-Service General Hospital and other collaborators

Recruiting

Radiotherapy Versus Low-Dose Tamoxifen Following Breast Conserving Surgery for Low-Risk Breast Ductal Carcinoma in Situ

Breast Ductal Carcinoma in Situ

Taiwan
Mundipharma Research Limited

Completed

A Pharmacokinetic/Pharmacodynamic Inhaler Comparison Study in Healthy Volunteers

Asthma

United Kingdom
Centro Hospitalar Lisboa Ocidental

Not yet recruiting

Breast Cancer Active Surveillance, Alternative Option, Aspirin Included

Breast Cancer
Chengdu Suncadia Medicine Co., Ltd.

Completed

Investigation of Drug-drug Interaction of HRS-5965 With Clopidogrel and Clarithromycin in Healthy Subjects

Hemolytic Anemia | Complement Mediated Glomerular Diseases

China
Charite University, Berlin, Germany

Completed

A Phase I/II Study to Investigate the Use of VORAXAZE™ As Intended Intervention in Patients with CNSL (VALIDATE)

CNS Lymphoma

Germany
Rennes University Hospital

Completed

National Multicenter, Controlled, Single-blind Study With Two Parallel Groups Evaluating the Safety and Efficacy of Sequential Treatment With Mitoxantrone and Interferon Versus Interferon Alone in Patients With Strong Risk of Progression in the Initial Phase of Multiple Sclerosis (MITOX-REBIF)

Multiple Sclerosis

France
University Ghent
Flemish Interuniversity Council (VLIR); Arba Minch University, Ethiopia

Completed

Iron and Vitamin A in School Children (IronVitA)

Vitamin A Deficiency | Anemia, Iron Deficiency | Cognitive Development | Helminthic Infection

Ethiopia
Nantes University Hospital

Terminated

Post Transplant Cyclophosphamide (PTCY) as Sole Graft Versus Host Disease (GVHD) Prophylaxis for Matched Allotransplant: CYRIC (CYRIC)

Graft Versus Host Disease

France
The Netherlands Cancer Institute
Bristol-Myers Squibb

Active, not recruiting

Nivolumab After Induction Treatment in Triple-negative Breast Cancer (TNBC) Patients (TONIC)

Breast Cancer

Netherlands
Amgen

Completed

Phase 3b Safety and Efficacy Study of Apremilast to Treat Moderate to Severe Plaque-plaque Psoriasis

Psoriasis | Psoriatic Arthritis

United States, Canada, United Kingdom, Australia, Hungary, Belgium, Netherlands, Germany, Czechia, Estonia, Latvia
Teva Branded Pharmaceutical Products R&D, Inc.
Parexel

Completed

A Cumulative Dose Study to Evaluate the Safety and Efficacy of Albuterol in a Dry Powder Inhaler and an HFA MDI (Hydrofluoroalkane Metered Dose Inhaler)

Asthma

United States
Rafa Laboratories
Teva Branded Pharmaceutical Products R&D, Inc.

Terminated

Comparison of Delta-8-THC to Ondansetron in the Prevention of Acute Nausea From Moderately Emetogenic Chemotherapy

Cancer

Israel
Memorial Sloan Kettering Cancer Center
Astellas Pharma US, Inc.

Completed

Low Dose Daily Erlotinib in Combination With High Dose Twice Weekly Erlotinib in Patients With EGFR-Mutant Lung Cancer

EGFR-Mutant Lung Cancer

United States
University College Dublin
Royal College of Surgeons, Ireland; National Maternity Hospital, Ireland; Perinatal...

Completed

Trial of Early Screening Test for Pre-eclampsia and Growth Restriction (TEST)

Placenta Diseases | Pre-Eclampsia | Fetal Growth Retardation | Eclampsia Preeclampsia | Foetal Growth Restriction

Ireland
Assiut University

Completed

The Effect of Omega 3 on Pregnancy Complicated by Asymmetrical Intrauterine Growth Restriction

Intrauterine Growth Restriction

Egypt
Sheba Medical Center

Completed

Efficacy Study of Prophylactic Ibuprofen Versus Placebo on Pain Relief and Success Rates of Medical Abortion

Pain | Pregnancy

Israel
University of Ioannina

Unknown

Comparison of High-Dose Rosuvastatin Versus Low Statin Dose Plus Fenofibrate Versus Low Statin Dose Plus Niacin in the Treatment of Mixed Hyperlipidemia

Dyslipidemia

Greece
Peking University Third Hospital

Recruiting

Evaluation of the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Diabetic Patients

Diabetes

China
Johannes Gutenberg University Mainz

Completed

Comparison of Two Different Types of "Spray as You go" Technique for Awake Fiberoptic Intubation

Awake Fiberoptic Intubation

Germany
Hui-Chuan Sun

Recruiting

Hepatic Artery Infusion Chemotherapy for Unresectable Hepatocelluar Carcinoma Who Failed to Systemic Therapy

Hepatocellular Carcinoma

China
University of California, Los Angeles
Tobacco Related Disease Research Program

Completed

Smoking and Ventricular Repolarization

Sudden Cardiac Death | Prolonged QTc Interval

United States
Haukeland University Hospital

Recruiting

Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism

Primary Aldosteronism | Hypercortisolism | Aldosterone-Producing Adenoma

Norway
Sun Yat-sen University
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Trial of Hepatic Arterial Infusion Combined With Apatinib and Camrelizumab Versus Apatinib and Camrelizumab for C-staged Hepatocellular Carcinoma in BCLC Classification (TRIPLET-III)

C-staged Hepatocellular Carcinoma in BCLC Classification

China
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Quantification of Dynamic and Static Cerebral Autoregulation (CA) Under Anaesthesia (SAMBA)

Cerebrovascular Circulation

Netherlands
Aquestive Therapeutics
Syneos Health; Covance

Completed

Safety and Tolerability Study of Diazepam Buccal Film (DBF) in Subjects With Epilepsy (DBF)

Epilepsy

United States
Centre Hospitalier Sud Francilien
Centre National de Ressources de lutte contre la Douleur

Completed

Prevention of Pain Caused by the Oro-gastric Tube Laying in Neonatology (DOLATSONG)

Pain Score

France
SOTIO a.s.

Completed

DCVAC/OvCa After Standard-of-care Chemotherapy in Women With Relapse of Platinum-sensitive Epithelial Ovarian Cancer

Ovarian Cancer Recurrent

Czechia

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