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Undersøgelse af Tamoxifen og Raloxifen (STAR) til forebyggelse af brystkræft hos postmenopausale kvinder

5. oktober 2015 opdateret af: NSABP Foundation Inc

Undersøgelse af Tamoxifen og Raloxifen (STAR) til forebyggelse af brystkræft

RATIONALE: Østrogen kan stimulere væksten af brystkræftceller. Hormonbehandling med raloxifen og tamoxifen kan bekæmpe brystkræft ved at blokere tumorcellernes optagelse af østrogen.

FORMÅL: Randomiseret dobbeltblindet klinisk forsøg for at sammenligne effektiviteten af raloxifen med tamoxifens effektivitet til at forebygge brystkræft hos postmenopausale kvinder.

Studieoversigt

Status

Afsluttet

Betingelser

Brystkræft

Intervention / Behandling

Detaljeret beskrivelse

MÅL:

Bestem, om raloxifen er mere eller mindre effektiv end tamoxifen til signifikant at reducere forekomsten af invasiv brystkræft hos postmenopausale kvinder.
Evaluer virkningerne af tamoxifen og raloxifen på forekomsten af intraduktalt carcinom in situ, lobulært carcinom in situ, endometriecancer, iskæmisk hjertesygdom, brud på hoften og rygsøjlen eller Colles' brud på håndleddet hos disse deltagere.
Evaluer de toksiske virkninger af disse regimer hos disse deltagere.
Bestem effekten af disse regimer på livskvaliteten for disse deltagere (på udvalgte centre). (Livskvalitetsevaluering lukket til periodisering med virkning fra 31/5/01.)

OVERSIGT: Dette er et randomiseret, dobbeltblindt studie. Deltagerne er stratificeret efter alder (35 til 49 vs. 50 til 59 vs risiko for invasiv brystkræft inden for 5 år (ved brug af Gail-modellen) (mindre end 2,0 vs 2,0-2,9 vs 3,0-4,9 vs. 5.0 eller højere). Deltagerne randomiseres til 1 af 2 arme.

Arm I: Deltagerne får oral tamoxifen plus placebo dagligt i 5 år.
Arm II: Deltagerne får oral raloxifen plus placebo dagligt i 5 år. Livskvalitet vurderes (på udvalgte centre) ved baseline og ved 6, 12, 18, 24, 30, 36, 42, 48, 54, 60 og 72 måneder. (Livskvalitetsevaluering lukket til periodisering med virkning fra 31/5/01.)

Deltagerne følges årligt efter 5 år.

PROJEKTERET TILSLUTNING: Der vil blive akkumuleret ca. 19.000 deltagere til denne undersøgelse inden for 5 år.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

19747

Fase

Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Canada
- Alberta
  - Calgary, Alberta, Canada, T2N 4N2
    - Tom Baker Cancer Center - Calgary
  - Edmonton, Alberta, Canada, T6G 1Z2
    - Cross Cancer Institute
- British Columbia
  - Vancouver, British Columbia, Canada, V6T 2B5
    - University Hospital - U.B.C. Site
- Manitoba
  - Winnipeg, Manitoba, Canada, R3E 0V9
    - CancerCare Manitoba
- Ontario
  - Kingston, Ontario, Canada, K7L 5P9
    - Familial Oncology Program
  - Mississauga, Ontario, Canada, L5M 2N1
    - Credit Valley Hospital
  - North York, Ontario, Canada, M2E 1K1
    - North York General Hospital, Ontario
  - Ottawa, Ontario, Canada, K1H 1C4
    - Ottawa Regional Cancer Centre
  - Thunder Bay, Ontario, Canada, P7A 7T1
    - Northwestern Ontario Regional Cancer Care
  - Toronto, Ontario, Canada, M5G 2C4
    - Toronto General Hospital
  - Toronto, Ontario, Canada, M4N 3M5
    - Toronto Sunnybrook Regional Cancer Centre
  - Toronto, Ontario, Canada, M5B 1W8
    - St. Michael's Hospital - Toronto
  - Toronto, Ontario, Canada, M5S 1B6
    - Women's College Ambulatory Care Center, Sunnybrook and Women's College Health Science Center
- Quebec
  - Fleurimont, Quebec, Canada, J1H 5N4
    - CHUS-Hopital Fleurimont
  - Greenfield Park, Quebec, Canada, J4V 2H1
    - Hopital Charles LeMoyne
  - Montreal, Quebec, Canada, H3G 1A4
    - Montreal General Hospital
  - Montreal, Quebec, Canada, H3A 1A1
    - Royal Victoria Hospital - Montreal
  - Montreal, Quebec, Canada, H2L-4M1
    - Centre Hospitalier de L'Universite de Montreal
  - Montreal, Quebec, Canada, H3T 1E2
    - Jewish General Hospital - Montreal
  - Montreal, Quebec, Canada, H3G 1L5
    - Ville Marie Breast Center
  - Quebec City, Quebec, Canada, G1S 4L8
    - Hopital du Saint-Sacrement, Quebec
  - Sherbrooke, Quebec, Canada, J1H 5N4
    - Centre Universitaire de Sante de l'Estrie
- Saskatchewan
  - Saskatoon, Saskatchewan, Canada, S7N 4H4
    - Saskatoon Cancer Centre
Forenede Stater
- Alabama
  - Huntsville, Alabama, Forenede Stater, 35801
    - Comprehensive Cancer Institute
  - Mobile, Alabama, Forenede Stater, 36688
    - MBCCOP - Gulf Coast
- Alaska
  - Anchorage, Alaska, Forenede Stater, 99519-6604
    - Providence Alaska Medical Center
- Arizona
  - Phoenix, Arizona, Forenede Stater, 85006-2726
    - CCOP - Western Regional, Arizona
  - Scottsdale, Arizona, Forenede Stater, 85259-5404
    - CCOP - Mayo Clinic Scottsdale Oncology Program
  - Tucson, Arizona, Forenede Stater, 85724
    - Arizona Cancer Center at University of Arizona Health Sciences Center
- Arkansas
  - Fayetteville, Arkansas, Forenede Stater, 72703
    - Breast Associates
  - Fort Smith, Arkansas, Forenede Stater, 72917
    - Surgical Associates
  - Jonesboro, Arkansas, Forenede Stater, 72401
    - Northeast Arkansas Clinic
  - Little Rock, Arkansas, Forenede Stater, 72205
    - Arkansas Cancer Research Center at University of Arkansas for Medical Sciences
- California
  - Anaheim, California, Forenede Stater, 92805
    - Kaiser Permanente Medical Center - Anaheim/Orange County
  - Baldwin Park, California, Forenede Stater, 91706
    - Kaiser Permanente Medical Center - Baldwin Park
  - Bellflower, California, Forenede Stater, 90706
    - Kaiser Permanente Medical Center - Bellflower
  - Berkeley, California, Forenede Stater, 94704
    - Alta Bates Comprehensive Cancer Center
  - Burbank, California, Forenede Stater, 91505
    - Providence Saint Joseph Medical Center - Burbank
  - Burlingame, California, Forenede Stater, 94010
    - Mills-Peninsula Health Services
  - Chico, California, Forenede Stater, 95926
    - Enloe Cancer Center at Enloe Medical Center
  - Concord, California, Forenede Stater, 94524-4110
    - Mount Diablo Medical Center
  - Corona, California, Forenede Stater, 92882-3400
    - Corona Regional Medical Center
  - Duarte, California, Forenede Stater, 91010-3000
    - City of Hope Comprehensive Cancer Center
  - Encinitas, California, Forenede Stater, 92024
    - Scripps Memorial Hospitals-Stevens Cancer Center - Encinitas
  - Fairfield, California, Forenede Stater, 94533
    - North Bay Cancer Center
  - Fontana, California, Forenede Stater, 92335
    - Kaiser Permanente Medical Center - Fontana
  - Fullerton, California, Forenede Stater, 92835
    - Crosson Cancer Center at St. Jude Medical Center
  - Glendale, California, Forenede Stater, 91204
    - Glendale Memorial Hospital Comprehensive Cancer Center
  - Granada Hills, California, Forenede Stater, 91344
    - Oncology/Hematology Associates
  - Greenbrae, California, Forenede Stater, 94904
    - Marin General Hospital Cancer Institute
  - Harbor City, California, Forenede Stater, 90710
    - Kaiser Permanente Medical Center - Harbor City
  - Hemet, California, Forenede Stater, 92543
    - Hemet Valley Medical Center
  - La Jolla, California, Forenede Stater, 92093-0658
    - Rebecca and John Moores UCSD Cancer Center
  - Lancaster, California, Forenede Stater, 93534
    - Valley Tumor Medical Group
  - Loma Linda, California, Forenede Stater, 92354
    - Loma Linda University Cancer Institute at Loma Linda University Medical Center
  - Long Beach, California, Forenede Stater, 90801-1428
    - Todd Cancer Institute at Long Beach Memorial Medical Center
  - Long Beach, California, Forenede Stater, 90813
    - Pacific Shores Medical Group Comprehensive Hematology-Oncology Services - Long Beach
  - Los Angeles, California, Forenede Stater, 90095-1781
    - Jonsson Comprehensive Cancer Center, UCLA
  - Los Angeles, California, Forenede Stater, 90027
    - Kaiser Permanente Medical Center - Los Angeles
  - Los Angeles, California, Forenede Stater, 90033-0804
    - USC/Norris Comprehensive Cancer Center and Hospital
  - Los Angeles, California, Forenede Stater, 90033
    - Cecilia Gonzalez De La Hoya Cancer Center at White Memorial Medical Center
  - Los Angeles, California, Forenede Stater, 90034
    - Kaiser Foundation Hospital - West Los Angeles
  - Los Angeles, California, Forenede Stater, 90057-1901
    - St. Vincent Medical Center - Los Angeles
  - Mission Viejo, California, Forenede Stater, 92691
    - Mission Cancer Center at Mission Hospital
  - Modesto, California, Forenede Stater, 95353
    - Sutter Gould Medical Foundation
  - Northridge, California, Forenede Stater, 91328
    - Leavey Cancer Center at Northridge Hospital Medical Center
  - Oceanside, California, Forenede Stater, 92056
    - Breast Health Center
  - Orange, California, Forenede Stater, 92868
    - Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center
  - Orange, California, Forenede Stater, 92868-3849
    - St. Joseph Hospital Regional Cancer Center - Orange
  - Oxnard, California, Forenede Stater, 93030
    - Ventura Hematology - Oncology Specialists - Oxnard
  - Palm Springs, California, Forenede Stater, 92262
    - Comprehensive Cancer Centers of the Desert
  - Palo Alto, California, Forenede Stater, 95819-5156
    - Palo Alto Medical Foundation
  - Panorama City, California, Forenede Stater, 91402
    - Kaiser Permanente Medical Group
  - Pasadena, California, Forenede Stater, 91109-7013
    - Huntington Cancer Center at Huntington Hospital
  - Pomona, California, Forenede Stater, 91767-3021
    - Wilshire Oncology Medical Group, Incorporated - Pomona
  - Redding, California, Forenede Stater, 96001
    - North Valley Breast Clinic
  - Riverside, California, Forenede Stater, 92505
    - Kaiser Permanente Medical Center - Riverside
  - Roseville, California, Forenede Stater, 95661
    - Sutter Roseville Medical Center
  - Sacramento, California, Forenede Stater, 95819-5156
    - Sutter Breast Cancer Group
  - San Diego, California, Forenede Stater, 92134-3202
    - Naval Medical Center - San Diego
  - San Diego, California, Forenede Stater, 92120
    - Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego
  - San Francisco, California, Forenede Stater, 94143-0128
    - UCSF Comprehensive Cancer Center
  - San Francisco, California, Forenede Stater, 94118-1618
    - California Pacific Medical Center - California Campus
  - Santa Barbara, California, Forenede Stater, 93105
    - Cancer Center of Santa Barbara
  - Santa Rosa, California, Forenede Stater, 95403
    - CCOP - Santa Rosa Memorial Hospital
  - Stanford, California, Forenede Stater, 94305-5408
    - Stanford Cancer Center at Stanford University Medical Center
  - Torrance, California, Forenede Stater, 90505
    - Torrance Memorial Medical Center
  - Valencia, California, Forenede Stater, 91355
    - Santa Clarita Valley Cancer Center - UCLA
  - Vallejo, California, Forenede Stater, 94589
    - Kaiser Permanente Medical Center - Vallejo
  - Woodland Hills, California, Forenede Stater, 91365-4084
    - Kaiser Permanente Medical Cener - Woodland Hills
- Colorado
  - Colorado Springs, Colorado, Forenede Stater, 80933
    - Penrose Cancer Center
  - Denver, Colorado, Forenede Stater, 80209-5031
    - CCOP - Colorado Cancer Research Program, Incorporated
  - Fort Collins, Colorado, Forenede Stater, 80524
    - Poudre Valley Hospital
  - Pueblo, Colorado, Forenede Stater, 81004
    - St. Mary-Corwin Regional Medical Center
- Connecticut
  - Farmington, Connecticut, Forenede Stater, 06360-7106
    - University of Connecticut Comprehensive Cancer Center at University of Connecticut Health Center
  - Hartford, Connecticut, Forenede Stater, 06105
    - St. Francis Hospital and Medical Center
  - Hartford, Connecticut, Forenede Stater, 06102-5037
    - Hartford Hospital
  - Manchester, Connecticut, Forenede Stater, 06040-4188
    - Manchester Memorial Hospital
  - Meriden, Connecticut, Forenede Stater, 06451
    - Midstate Medical Center
  - New Britain, Connecticut, Forenede Stater, 06050
    - New Britain General Hospital
  - New Haven, Connecticut, Forenede Stater, 06520-8028
    - Yale Comprehensive Cancer Center
  - New Haven, Connecticut, Forenede Stater, 06511
    - Hospital of St. Raphael
  - New London, Connecticut, Forenede Stater, 06320
    - Lawrence and Memorial Hospital
  - Norwich,, Connecticut, Forenede Stater, 06360
    - Eastern Connecticut Hematology and Oncology Associates
  - Stamford, Connecticut, Forenede Stater, 06902
    - Hematology Oncology, P.C.
  - Torrington, Connecticut, Forenede Stater, 06790
    - Northwestern Connecticut Oncology-Hematology Associates
  - Williamantic, Connecticut, Forenede Stater, 06226
    - Windham Community Memorial Hospital
- Delaware
  - Lewes, Delaware, Forenede Stater, 19958
    - Beebe Medical Center
  - Seaford, Delaware, Forenede Stater, 19973
    - Nanticoke Memorial Hospital
  - Wilmington, Delaware, Forenede Stater, 19899
    - CCOP - Christiana Care Health Services
- District of Columbia
  - Washington, District of Columbia, Forenede Stater, 20010
    - Washington Hospital Center
  - Washington, District of Columbia, Forenede Stater, 20007
    - Lombardi Cancer Center at Georgetown University Medical Center
  - Washington, District of Columbia, Forenede Stater, 20017
    - Providence Hospital
- Florida
  - Atlantis, Florida, Forenede Stater, 33462
    - JFK Medical Center
  - Jacksonville, Florida, Forenede Stater, 32224
    - Mayo Clinic - Jacksonville
  - Jacksonville, Florida, Forenede Stater, 32203
    - St. Vincent's Medical Center
  - Jacksonville, Florida, Forenede Stater, 32207
    - Baptist Regional Cancer Institute - Jacksonville
  - Jupiter, Florida, Forenede Stater, 33458
    - Ella Milbank Foshay Cancer Center at Jupiter Medical Center
  - Lakeland, Florida, Forenede Stater, 33804-5000
    - Watson Clinic
  - Lakeland, Florida, Forenede Stater, 33804
    - Lakeland Regional Cancer Center at Lakeland Regional Medical Center
  - Miami, Florida, Forenede Stater, 33136
    - University of Miami Sylvester Cancer Center
  - Miami Beach, Florida, Forenede Stater, 33140
    - CCOP - Mount Sinai Medical Center
  - Orlando, Florida, Forenede Stater, 32806
    - MD Anderson Cancer Center Orlando
  - Orlando, Florida, Forenede Stater, 32803-1273
    - Florida Hospital Medical Center
  - Pensacola, Florida, Forenede Stater, 32514-6088
    - West Florida Regional Medical Center
  - Plantation, Florida, Forenede Stater, 33324
    - Cancer Research Network Inc.
  - Stuart, Florida, Forenede Stater, 34996
    - Clinical Research Center of South Florida
  - Tampa, Florida, Forenede Stater, 33612-9497
    - H. Lee Moffitt Cancer Center and Research Institute
  - West Palm Beach, Florida, Forenede Stater, 33401
    - Palm Beach Cancer Institute
- Georgia
  - Atlanta, Georgia, Forenede Stater, 30342-1701
    - CCOP - Atlanta Regional
  - Augusta, Georgia, Forenede Stater, 30912
    - Medical College of Georgia
  - Savannah, Georgia, Forenede Stater, 31403-3089
    - Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
  - Savannah, Georgia, Forenede Stater, 31405-6013
    - Cancer Care and Research Pavilion at St. Joseph's/Candler
- Hawaii
  - Honolulu, Hawaii, Forenede Stater, 96813
    - MBCCOP - Hawaii
- Idaho
  - Coeur d'Alene, Idaho, Forenede Stater, 83814
    - North Idaho Cancer Center
- Illinois
  - Arlington Heights, Illinois, Forenede Stater, 60005
    - Northwest Community Hospital
  - Aurora, Illinois, Forenede Stater, 60504-4206
    - Rush Copley Medical Center
  - Chicago, Illinois, Forenede Stater, 60612-7323
    - MBCCOP - University of Illinois at Chicago
  - Chicago, Illinois, Forenede Stater, 60637-1470
    - University of Chicago Cancer Research Center
  - Chicago, Illinois, Forenede Stater, 60611
    - Northwestern Memorial Hospital
  - Chicago, Illinois, Forenede Stater, 60611-3013
    - Robert H. Lurie Comprehensive Cancer Center at Northwestern University
  - Chicago, Illinois, Forenede Stater, 60657
    - Creticos Cancer Center at Advocate Illinois Masonic Medical Center
  - Chicago, Illinois, Forenede Stater, 60612
    - Rush Cancer Institute at Rush University Medical Center
  - Chicago, Illinois, Forenede Stater, 60612-9985
    - John H. Stroger, Jr. Hospital of Cook County
  - Chicago, Illinois, Forenede Stater, 60631
    - Resurrection Medical Center
  - Chicago, Illinois, Forenede Stater, 60634
    - Our Lady of the Resurrection Medical Center
  - Decatur, Illinois, Forenede Stater, 62526
    - CCOP - Central Illinois
  - Elgin, Illinois, Forenede Stater, 60120-2198
    - Sherman Hospital
  - Evanston, Illinois, Forenede Stater, 60201
    - CCOP - Evanston
  - Evanston, Illinois, Forenede Stater, 60202
    - St. Francis Hospital
  - Harvey, Illinois, Forenede Stater, 60426
    - Ingalls Memorial Hospital
  - Hazel Crest, Illinois, Forenede Stater, 60429
    - Advocate South Suburban Hospital
  - Highland Park, Illinois, Forenede Stater, 60035-2497
    - Evanston Northwestern Health Care - Highland Park Hospital
  - Hinsdale, Illinois, Forenede Stater, 60521
    - Hinsdale Hematology Oncology Associates
  - Joliet, Illinois, Forenede Stater, 60435
    - Joliet Oncology Hematology Associates, Limited - Joliet
  - Maywood, Illinois, Forenede Stater, 60153
    - Cardinal Bernardin Cancer Center at Loyola University Medical Center
  - Naperville, Illinois, Forenede Stater, 60540-7499
    - Edward Hospital Cancer Center
  - Normal, Illinois, Forenede Stater, 61761
    - Mid-Illinois Hematology-Oncology Associates
  - Oak Lawn, Illinois, Forenede Stater, 60453
    - Advocate Christ Medical Center
  - Olympia Fields, Illinois, Forenede Stater, 60461
    - Saint James Hospital and Health Centers Comprehensive Cancer Institute
  - Park Ridge, Illinois, Forenede Stater, 60068
    - Lutheran General Cancer Care Center
  - Peoria, Illinois, Forenede Stater, 61602
    - CCOP - Illinois Oncology Research Association
  - Rock Island, Illinois, Forenede Stater, 61201
    - Trinity Medical Center - West
  - Rockford, Illinois, Forenede Stater, 61108
    - Saint Anthony Medical Center
  - Rockford, Illinois, Forenede Stater, 61104-2315
    - Swedish-American Regional Cancer Center
  - Rockford, Illinois, Forenede Stater, 61103
    - Rockford Clinic
  - Skokie, Illinois, Forenede Stater, 60076
    - Edward H. Kaplan MD and Associates
  - Springfield, Illinois, Forenede Stater, 62781
    - Memorial Medical Center
  - Springfield, Illinois, Forenede Stater, 62769
    - St. John's Hospital
  - Urbana, Illinois, Forenede Stater, 61801
    - CCOP - Carle Cancer Center
- Indiana
  - Goshen, Indiana, Forenede Stater, 46526
    - Center for Cancer Care at Goshen Health System
  - Indianapolis, Indiana, Forenede Stater, 46260
    - St. Vincent Hospital and Health Care Center
  - Indianapolis, Indiana, Forenede Stater, 46202
    - Indiana Community Cancer Care, Incorporated
  - Indianapolis, Indiana, Forenede Stater, 46206-1367
    - Methodist Cancer Center at Methodist Hospital
  - Indianapolis, Indiana, Forenede Stater, 46256
    - Indiana Regional Cancer Center
  - Lafayette, Indiana, Forenede Stater, 47904
    - Oncology Institute of Greater Lafayette
  - Michigan City, Indiana, Forenede Stater, 46360
    - Saint Anthony Memorial Health Centers
  - Muncie, Indiana, Forenede Stater, 47303-3499
    - Ball Memorial Hospital Cancer Center
  - Munster, Indiana, Forenede Stater, 46321
    - Community Hospital
  - South Bend, Indiana, Forenede Stater, 46601
    - CCOP - Northern Indiana CR Consortium
- Iowa
  - Ames, Iowa, Forenede Stater, 50010
    - McFarland Clinic, P.C.
  - Cedar Rapids, Iowa, Forenede Stater, 52403-1206
    - CCOP - Cedar Rapids Oncology Project
  - Clinton, Iowa, Forenede Stater, 52732-5031
    - Medical Associates
  - Council Bluffs, Iowa, Forenede Stater, 51503
    - Jennie Edmundson Memorial Hospital
  - Davenport, Iowa, Forenede Stater, 52803
    - Genesis Regional Cancer Center at Genesis Medical Center
  - Des Moines, Iowa, Forenede Stater, 50309-1016
    - CCOP - Iowa Oncology Research Association
  - Dubuque, Iowa, Forenede Stater, 52001
    - Wendt Regional Cancer Center of Finley Hospital
  - Iowa City, Iowa, Forenede Stater, 52242-1009
    - Holden Comprehensive Cancer Center at University of Iowa
  - Mason City, Iowa, Forenede Stater, 50401
    - Mercy Cancer Center at Mercy Medical Center - North Iowa
  - Ottumwa, Iowa, Forenede Stater, 52501
    - Ottumwa Regional Health Center
  - Sioux City, Iowa, Forenede Stater, 51101-1733
    - Siouxland Hematology-Oncology
  - Waterloo, Iowa, Forenede Stater, 50701
    - Cedar Valley Medical Specialists, P.C.
- Kansas
  - Kansas City, Kansas, Forenede Stater, 66160-7357
    - Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center
  - Wichita, Kansas, Forenede Stater, 67214-3882
    - CCOP - Wichita
- Kentucky
  - Ashland, Kentucky, Forenede Stater, 41101
    - King's Daughters Medical Center
  - Edgewood, Kentucky, Forenede Stater, 41017
    - St. Elizabeth Medical Center
  - Frankfort, Kentucky, Forenede Stater, 40601
    - HCA Kings Daughters Memorial Hospital
  - Lexington, Kentucky, Forenede Stater, 40503
    - Central Baptist Hospital
  - Lexington, Kentucky, Forenede Stater, 40536-0093
    - Markey Cancer Center at University of Kentucky Chandler Medical Center
  - Louisville, Kentucky, Forenede Stater, 40207
    - Baptist Hospital East - Louisville
  - Louisville, Kentucky, Forenede Stater, 40202
    - James Graham Brown Cancer Center at University of Louisville
  - Louisville, Kentucky, Forenede Stater, 40202-5070
    - Norton Healthcare Cancer Center
- Louisiana
  - Baton Rouge, Louisiana, Forenede Stater, 70809
    - Ochsner Clinic of Baton Rouge
  - Baton Rouge, Louisiana, Forenede Stater, 70821-2511
    - Baton Rouge General Medical Center
  - Houma, Louisiana, Forenede Stater, 70360
    - Cancer Care Specialists
  - New Orleans, Louisiana, Forenede Stater, 70121
    - CCOP - Ochsner
  - New Orleans, Louisiana, Forenede Stater, 70112
    - MBCCOP - LSU Health Sciences Center
  - New Orleans, Louisiana, Forenede Stater, 70112
    - Tulane Cancer Center at Tulane University Hospital and Clinic
  - Shreveport, Louisiana, Forenede Stater, 71101
    - Cancer Treatment Center at Christus Schumpert St. Mary Place
- Maine
  - Bangor, Maine, Forenede Stater, 04401
    - Eastern Maine Medical Center
  - Sanford, Maine, Forenede Stater, 04073
    - Goodall Hospital
  - Scarborough, Maine, Forenede Stater, 04074
    - Maine Center for Cancer Medicine and Blood Disorders - Scarborough
- Maryland
  - Annapolis, Maryland, Forenede Stater, 21401
    - Anne Arundel Medical Center
  - Baltimore, Maryland, Forenede Stater, 21231-2410
    - Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  - Baltimore, Maryland, Forenede Stater, 21204
    - Greater Baltimore Medical Center and Cancer Center
  - Baltimore, Maryland, Forenede Stater, 21201
    - Greenebaum Cancer Center at University of Maryland Medical Center
  - Baltimore, Maryland, Forenede Stater, 21237
    - Franklin Square Hospital Center
  - Bethesda, Maryland, Forenede Stater, 20814
    - Suburban Hospital
  - Frederick, Maryland, Forenede Stater, 21701
    - Frederick Memorial Hospital Regional Cancer Therapy Center
- Massachusetts
  - Boston, Massachusetts, Forenede Stater, 02215
    - Beth Israel Deaconess Medical Center
  - Boston, Massachusetts, Forenede Stater, 02115
    - Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute
  - Boston, Massachusetts, Forenede Stater, 02114
    - Massachusetts General Hospital Cancer Center
  - Boston, Massachusetts, Forenede Stater, 02118
    - Cancer Research Center at Boston Medical Center
  - Boston, Massachusetts, Forenede Stater, 02215
    - Harvard Vanguard Medical Associates - Kenmore
  - Burlington, Massachusetts, Forenede Stater, 01805
    - Lahey Clinic Medical Center - Burlington
  - Fall River, Massachusetts, Forenede Stater, 02721
    - Saint Anne's Hospital
  - Norfolk, Massachusetts, Forenede Stater, 02062
    - Caritas Norwood Hospital
  - Peabody, Massachusetts, Forenede Stater, 01960
    - NSMC Cancer Center
  - Pittsfield, Massachusetts, Forenede Stater, 01201
    - Berkshire Physicians and Surgeons, P.C.
  - Plymouth, Massachusetts, Forenede Stater, 02360
    - Jordan Hospital Club Cancer Center
  - Springfield, Massachusetts, Forenede Stater, 01199
    - Baystate Regional Cancer Program at Baystate Medical Center
  - Worcester, Massachusetts, Forenede Stater, 01655
    - University of Massachusetts Memorial Medical Center - University Campus
- Michigan
  - Adrian, Michigan, Forenede Stater, 49221
    - Hickman Cancer Center at Bixby Medical Center
  - Ann Arbor, Michigan, Forenede Stater, 48109-0752
    - University of Michigan Comprehensive Cancer Center
  - Ann Arbor, Michigan, Forenede Stater, 48106
    - CCOP - Michigan Cancer Research Consortium
  - Battle Creek, Michigan, Forenede Stater, 49016
    - Battle Creek Health System
  - Bay City, Michigan, Forenede Stater, 48708
    - Bay Diagnostic Center for Women
  - Coldwater, Michigan, Forenede Stater, 49036
    - Community Health Center of Branch County
  - Dearborn, Michigan, Forenede Stater, 48123-2500
    - Oakwood Hospital and Medical Center
  - Detroit, Michigan, Forenede Stater, 48202
    - Josephine Ford Cancer Center at Henry Ford Hospital
  - Detroit, Michigan, Forenede Stater, 48201-1379
    - Barbara Ann Karmanos Cancer Institute
  - Detroit, Michigan, Forenede Stater, 48236
    - St. John Hospital and Medical Center
  - Flint, Michigan, Forenede Stater, 48503
    - Hurley Medical Center
  - Flint, Michigan, Forenede Stater, 48532
    - Flint Hematology Oncology
  - Grand Blanc, Michigan, Forenede Stater, 48439-8066
    - Genesys Regional Medical Center
  - Grand Rapids, Michigan, Forenede Stater, 49503
    - CCOP - Grand Rapids
  - Holland, Michigan, Forenede Stater, 49423
    - Holland Community Hospital
  - Jackson, Michigan, Forenede Stater, 49201
    - Center for Hematology/Oncology
  - Kalamazoo, Michigan, Forenede Stater, 49007-3731
    - CCOP - Kalamazoo
  - Lansing, Michigan, Forenede Stater, 48912
    - Michigan State University Department of Surgery
  - Lapeer, Michigan, Forenede Stater, 48446
    - Lapeer Regional Hospital
  - Marquette, Michigan, Forenede Stater, 49855
    - Marquette General Hospital
  - Monroe, Michigan, Forenede Stater, 48161-0067
    - Mercy Memorial Hospital, Corporation
  - Mount Clemens, Michigan, Forenede Stater, 48043
    - Community Cancer Care Specialist
  - Owosso, Michigan, Forenede Stater, 48867
    - Memorial Healthcare
  - Port Huron, Michigan, Forenede Stater, 48060
    - Blue Water Oncology PC, Port Huron
  - Royal Oak, Michigan, Forenede Stater, 48073-6769
    - CCOP - Beaumont
  - Saginaw, Michigan, Forenede Stater, 48601
    - Saint Mary's Seton Cancer Institute
  - Southfield, Michigan, Forenede Stater, 48075-9975
    - Providence Cancer Institute at Providence Hospital
  - Traverse City, Michigan, Forenede Stater, 49684
    - Munson Medical Center
  - Warren, Michigan, Forenede Stater, 48093-3494
    - St. John Macomb Hospital
- Minnesota
  - Duluth, Minnesota, Forenede Stater, 55805
    - CCOP - Duluth
  - Duluth, Minnesota, Forenede Stater, 55805
    - St. Luke's Medical Clinic
  - Minneapolis, Minnesota, Forenede Stater, 55455
    - University of Minnesota
  - Minneapolis, Minnesota, Forenede Stater, 55415
    - Hennepin County Medical Center - Minneapolis
  - Minneapolis, Minnesota, Forenede Stater, 55407
    - Minnesota Cooperative Group Program
  - Rochester, Minnesota, Forenede Stater, 55905
    - Mayo Clinic Cancer Center
  - Saint Louis Park, Minnesota, Forenede Stater, 55416
    - CCOP - Metro-Minnesota
  - Willmar, Minnesota, Forenede Stater, 56201
    - Rice Memorial Hospital
- Mississippi
  - Biloxi, Mississippi, Forenede Stater, 39530-4239
    - Coast Oncology/Hematology, P.L.L.C.
  - Cleveland, Mississippi, Forenede Stater, 38732
    - Mid Delta Family Practice
  - Hattiesburg, Mississippi, Forenede Stater, 39401
    - Hattiesburg Clinic, P.A.
  - Jackson, Mississippi, Forenede Stater, 39202
    - Jackson Oncology Associates, PLLC
  - Keesler AFB, Mississippi, Forenede Stater, 39534-2576
    - Keesler Medical Center - Keesler Air Force Base
  - Tupelo, Mississippi, Forenede Stater, 38801
    - North Mississippi Hematology and Oncology Associates, Limited
- Missouri
  - Chesterfield, Missouri, Forenede Stater, 63017
    - Saint Luke's Hospital
  - Columbia, Missouri, Forenede Stater, 65203
    - Ellis Fischel Cancer Center at University of Missouri - Columbia
  - Joplin, Missouri, Forenede Stater, 64804
    - St. John's Regional Medical Center
  - Joplin, Missouri, Forenede Stater, 64803-2644
    - Freeman Cancer Institute at Freeman Health System
  - Kansas City, Missouri, Forenede Stater, 64131
    - CCOP - Kansas City
  - Rolla, Missouri, Forenede Stater, 65401
    - Phelps County Regional Medical Center
  - Saint Louis, Missouri, Forenede Stater, 63110
    - Siteman Cancer Center
  - Saint Louis, Missouri, Forenede Stater, 63131
    - Missouri Baptist Cancer Center
  - Saint Louis, Missouri, Forenede Stater, 63141
    - CCOP - St. Louis-Cape Girardeau
  - Saint Louis, Missouri, Forenede Stater, 63109
    - Midwest Hematology Oncology Group, Inc.
  - Springfield, Missouri, Forenede Stater, 65804
    - St. John's Regional Health Center
  - Springfield, Missouri, Forenede Stater, 65807
    - CCOP - Cancer Research for the Ozarks
  - St. Charles, Missouri, Forenede Stater, 63301
    - Missouri Cancer Care, P.C. - St. Charles
  - West Plains, Missouri, Forenede Stater, 65775
    - Ozarks Medical Center
- Montana
  - Billings, Montana, Forenede Stater, 59101
    - CCOP - Montana Cancer Consortium
  - Great Falls, Montana, Forenede Stater, 59405
    - Montana Cancer Institute - Benefis Healthcare
  - Kalispell, Montana, Forenede Stater, 59901
    - Kalispell Regional Medical Center
- Nebraska
  - Grand Island, Nebraska, Forenede Stater, 68802
    - Saint Francis Medical Center
  - Kearney, Nebraska, Forenede Stater, 68848-1990
    - Cancer Center at the Good Samaritan Health Systems
  - Lincoln, Nebraska, Forenede Stater, 68510-4844
    - Cancer Resource Center - Lincoln
  - Omaha, Nebraska, Forenede Stater, 68131-2197
    - Creighton University Medical Center
  - Omaha, Nebraska, Forenede Stater, 68114
    - Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha
  - Omaha, Nebraska, Forenede Stater, 68124
    - Bergan Mercy Medical Center
  - Omaha, Nebraska, Forenede Stater, 68122
    - Alegent Health - Immanuel Medical Center
- Nevada
  - Las Vegas, Nevada, Forenede Stater, 89106
    - CCOP - Southern Nevada Cancer Research Foundation
- New Hampshire
  - Hooksett, New Hampshire, Forenede Stater, 03106
    - New Hampshire Oncology-Hematology, PA - Hooksett
  - Nashua, New Hampshire, Forenede Stater, 03061
    - Southern New Hampshire Medical Center
- New Jersey
  - Camden, New Jersey, Forenede Stater, 08103
    - Cooper Cancer Institute
  - Englewood, New Jersey, Forenede Stater, 07631
    - Englewood Hospital and Medical Center
  - Flemington, New Jersey, Forenede Stater, 08822
    - Hunterdon Regional Cancer Center
  - Hackensack, New Jersey, Forenede Stater, 07601
    - CCOP - Northern New Jersey
  - Livingston, New Jersey, Forenede Stater, 07039
    - St. Barnabas Medical Center
  - Long Branch, New Jersey, Forenede Stater, 07740-6395
    - Monmouth Medical Center
  - Millville, New Jersey, Forenede Stater, 08332
    - South Jersey Regional Cancer Center
  - Mount Holly, New Jersey, Forenede Stater, 08060
    - Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital
  - New Brunswick, New Jersey, Forenede Stater, 08903
    - Cancer Institute Of New Jersey
  - Newark, New Jersey, Forenede Stater, 07112
    - Newark Beth Israel Medical Center
  - Phillipsburg, New Jersey, Forenede Stater, 08865
    - Warren Hospital
  - Pomona, New Jersey, Forenede Stater, 08240
    - Atlantic City Medical Center
  - Red Bank, New Jersey, Forenede Stater, 07701
    - Booker Cancer Center at Riverview Medical Center
  - Ridgewood, New Jersey, Forenede Stater, 07450
    - Valley Hospital
  - Somerville, New Jersey, Forenede Stater, 08876
    - Somerset Medical Center
  - Toms River, New Jersey, Forenede Stater, 08755
    - Community Medical Center
  - Trenton, New Jersey, Forenede Stater, 08607
    - Capital Health System at Mercer
  - Woodbury, New Jersey, Forenede Stater, 08096
    - Underwood Memorial Hospital
- New Mexico
  - Albuquerque, New Mexico, Forenede Stater, 87131
    - University of New Mexico Cancer Research and Treatment Center
  - Albuquerque, New Mexico, Forenede Stater, 87102
    - Hematology-Oncology Associates, PC
  - Albuquerque, New Mexico, Forenede Stater, 87108
    - Lovelace Medical Center at Lovelace Sandia Health System
  - Albuquerque, New Mexico, Forenede Stater, 87109
    - New Mexico Oncology-Hematology Consultants, Limited
  - Santa Fe, New Mexico, Forenede Stater, 87505-7670
    - New Mexico Cancer Care Associates
- New York
  - Albany, New York, Forenede Stater, 12208
    - New York Oncology Hematology, P.C. - Albany Regional Cancer Center
  - Bronx, New York, Forenede Stater, 10461
    - Albert Einstein Clinical Cancer Center
  - Bronx, New York, Forenede Stater, 10466
    - Comprehensive Cancer Center at Our Lady of Mercy Medical Center
  - Buffalo, New York, Forenede Stater, 14263-0001
    - Roswell Park Cancer Institute
  - Cooperstown, New York, Forenede Stater, 13326-1394
    - Louis Busch Hager Cancer Center at Mary Imogene Bassett Hospital
  - Glens Falls, New York, Forenede Stater, 12801
    - Charles R. Wood Foundation Cancer Center at Glens Falls Hospital
  - Jamaica, New York, Forenede Stater, 11432
    - Queens Cancer Center of Queens Hospital
  - Latham, New York, Forenede Stater, 12110-0610
    - New York Oncology Hematology, P.C. - Latham
  - Manhasset, New York, Forenede Stater, 11030
    - CCOP - North Shore University Hospital
  - New York, New York, Forenede Stater, 10021
    - Memorial Sloan-Kettering Cancer Center
  - New York, New York, Forenede Stater, 10016
    - NYU School of Medicine's Kaplan Comprehensive Cancer Center
  - New York, New York, Forenede Stater, 10032
    - Herbert Irving Comprehensive Cancer Center at Columbia University
  - New York, New York, Forenede Stater, 10011
    - Saint Vincent Catholic Medical Center of New York
  - Poughkeepsie, New York, Forenede Stater, 12601
    - Vassar Brothers Medical Center
  - Poughkeepsie, New York, Forenede Stater, 12601
    - St. Francis Hospital and Health Centers
  - Rochester, New York, Forenede Stater, 14642
    - James P. Wilmot Cancer Center at University of Rochester Medical Center
  - Rochester, New York, Forenede Stater, 14607
    - Genesee Surgical Associates
  - Rochester, New York, Forenede Stater, 14620
    - Gynecologic Oncology Associates
  - Stony Brook, New York, Forenede Stater, 11794-8174
    - University Hospital - Stony Brook
  - Syracuse, New York, Forenede Stater, 13217
    - CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C.
  - Syracuse, New York, Forenede Stater, 13210
    - University Hospital at State University of New York - Upstate Medical University
- North Carolina
  - Asheville, North Carolina, Forenede Stater, 28801
    - Mission Hospitals
  - Chapel Hill, North Carolina, Forenede Stater, 27599-7295
    - Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
  - Charlotte, North Carolina, Forenede Stater, 28232-2861
    - Blumenthal Cancer Center at Carolinas Medical Center
  - Charlotte, North Carolina, Forenede Stater, 28233-3549
    - Presbyterian Healthcare
  - Durham, North Carolina, Forenede Stater, 27710
    - Duke Comprehensive Cancer Center
  - Fayetteville, North Carolina, Forenede Stater, 28302-2000
    - Cape Fear Valley Health System
  - Gastonia, North Carolina, Forenede Stater, 28054
    - Gaston Hematology and Oncology
  - Goldsboro, North Carolina, Forenede Stater, 27534
    - Southeastern Medical Oncology Center
  - Greensboro, North Carolina, Forenede Stater, 27403-1199
    - Moses Cone Regional Cancer Center at Wesley Long Community Hospital
  - Greenville, North Carolina, Forenede Stater, 27858-4354
    - Leo W. Jenkins Cancer Center of University Health Systems of Eastern Carolina
  - Hendersonville, North Carolina, Forenede Stater, 28791
    - Pardee Memorial Hospital
  - High Point, North Carolina, Forenede Stater, 27262
    - Cornerstone Surgery
  - Raleigh, North Carolina, Forenede Stater, 27607
    - Raleigh Hematology/Oncology Associates, P.A. - Rex Cancer Center
  - Statesville, North Carolina, Forenede Stater, 28687-1828
    - Cancer Center at Iredell Memorial Hospital
  - Wilmington, North Carolina, Forenede Stater, 28402-9000
    - New Hanover Regional Medical Center
  - Winston-Salem, North Carolina, Forenede Stater, 27104-4241
    - CCOP - Southeast Cancer Control Consortium
  - Winston-Salem, North Carolina, Forenede Stater, 27157-1082
    - Comprehensive Cancer Center at Wake Forest University
  - Winston-Salem, North Carolina, Forenede Stater, 27103
    - Forsyth Medical Center
- North Dakota
  - Bismarck, North Dakota, Forenede Stater, 58501
    - Quain & Ramstad Clinic
  - Fargo, North Dakota, Forenede Stater, 58122
    - CCOP - Merit Care Hospital
- Ohio
  - Akron, Ohio, Forenede Stater, 44302
    - Akron General Medical Center
  - Canton, Ohio, Forenede Stater, 44708
    - Mercy Medical Center
  - Canton, Ohio, Forenede Stater, 44710
    - Aultman Hospital Cancer Center at Aultman Health Foundation
  - Cincinnati, Ohio, Forenede Stater, 45242
    - Bethesda North Hospital
  - Cincinnati, Ohio, Forenede Stater, 45219
    - Cancer Center at Christ Hospital
  - Cincinnati, Ohio, Forenede Stater, 45267-0502
    - Charles M. Barrett Cancer Center at University Hospital
  - Cleveland, Ohio, Forenede Stater, 44195
    - Cleveland Clinic Taussig Cancer Center
  - Cleveland, Ohio, Forenede Stater, 44106-5065
    - Ireland Cancer Center
  - Cleveland, Ohio, Forenede Stater, 44111
    - Fairview Hospital
  - Cleveland, Ohio, Forenede Stater, 44120
    - Kaiser Permanente
  - Columbus, Ohio, Forenede Stater, 43210-1240
    - Arthur G. James Cancer Hospital - Ohio State University
  - Columbus, Ohio, Forenede Stater, 43206
    - CCOP - Columbus
  - Findlay, Ohio, Forenede Stater, 45840
    - Blanchard Valley Medical Associates
  - Fremont, Ohio, Forenede Stater, 43420
    - Fremont Memorial Hospital
  - Independence, Ohio, Forenede Stater, 44131
    - Cleveland Clinic Cancer Center
  - Kettering, Ohio, Forenede Stater, 45429
    - CCOP - Dayton
  - Lima, Ohio, Forenede Stater, 45804
    - Lima Memorial Hospital
  - Maumee, Ohio, Forenede Stater, 43537
    - St. Luke's Hospital
  - Parma, Ohio, Forenede Stater, 44129
    - Parma Community General Hospital
  - Sandusky, Ohio, Forenede Stater, 44870
    - Firelands Regional Medical Center
  - Sylvania, Ohio, Forenede Stater, 43560
    - Flower Hospital - ProMedica Health System
  - Toledo, Ohio, Forenede Stater, 43608
    - St. Vincent Mercy Medical Center
  - Toledo, Ohio, Forenede Stater, 43606
    - Toledo Hospital
  - Toledo, Ohio, Forenede Stater, 43623
    - CCOP - Toledo Community Hospital
  - Toledo, Ohio, Forenede Stater, 43614-0008
    - Medical College of Ohio Cancer Institute
  - Toledo, Ohio, Forenede Stater, 43616
    - St. Charles Hospital
  - Toledo, Ohio, Forenede Stater, 43623
    - Toledo Clinic, Incorporated
  - Warrensville Heights, Ohio, Forenede Stater, 44122
    - Cleveland Clinic Health System STAR BCPT
  - Wauseon, Ohio, Forenede Stater, 43567
    - Fulton County Health Center
- Oklahoma
  - Muskogee, Oklahoma, Forenede Stater, 74401
    - Muskogee Regional Medical Center
  - Oklahoma City, Oklahoma, Forenede Stater, 73101
    - Frank C. Love Cancer Institute at St. Anthony Hospital
  - Oklahoma City, Oklahoma, Forenede Stater, 73109
    - Central Oklahoma Cancer Center at INTEGRIS Southwest Medical Center
  - Oklahoma City, Oklahoma, Forenede Stater, 73120
    - Mercy Health Center
  - Oklahoma City, Oklahoma, Forenede Stater, 73190
    - Oklahoma University Medical Center at University of Oklahoma Health Sciences Center
  - Tulsa, Oklahoma, Forenede Stater, 74136
    - CCOP - Oklahoma
  - Tulsa, Oklahoma, Forenede Stater, 74104
    - St. John Health System
- Oregon
  - Bend, Oregon, Forenede Stater, 97701
    - St. Charles Medical Center
  - Portland, Oregon, Forenede Stater, 97201-3098
    - Cancer Institute at Oregon Health and Science University
  - Portland, Oregon, Forenede Stater, 97213
    - CCOP - Columbia River Oncology Program
  - Portland, Oregon, Forenede Stater, 97227-1098
    - Kaiser Permanente Center for Health Research
- Pennsylvania
  - Abington, Pennsylvania, Forenede Stater, 19001
    - Abington Memorial Hospital
  - Allentown, Pennsylvania, Forenede Stater, 18102
    - Sacred Heart Hospital
  - Allentown, Pennsylvania, Forenede Stater, 18103
    - John and Dorothy Morgan Cancer Center at Lehigh Valley Hospital
  - Altoona, Pennsylvania, Forenede Stater, 16602
    - Bon Secours-Holy Family Health System
  - Bethlehem, Pennsylvania, Forenede Stater, 18015
    - St. Luke's Hospital Cancer Center
  - Bryn Mawr, Pennsylvania, Forenede Stater, 19010
    - Bryn Mawr Hospital
  - Danville, Pennsylvania, Forenede Stater, 17822-2001
    - Geisinger Medical Center
  - Darby, Pennsylvania, Forenede Stater, 19023
    - Mercy Fitzgerald Hospital
  - Doylestown, Pennsylvania, Forenede Stater, 18901
    - Doylestown Hospital
  - Drexel Hill, Pennsylvania, Forenede Stater, 19026
    - Delaware County Memorial Hospital
  - Easton, Pennsylvania, Forenede Stater, 18042
    - Easton Hospital
  - Ephrata, Pennsylvania, Forenede Stater, 17522-1002
    - Ephrata Community Hopital
  - Erie, Pennsylvania, Forenede Stater, 16505
    - Regional Cancer Center - Erie
  - Harrisburg, Pennsylvania, Forenede Stater, 17105-8700
    - Pinnacle Health Regional Cancer Center at Pinnacle Health System
  - Havertown, Pennsylvania, Forenede Stater, 19083
    - Mercy Community Hospital
  - Hershey, Pennsylvania, Forenede Stater, 17033-0850
    - Penn State Cancer Institute at Milton S. Hershey Medical Center
  - Lancaster, Pennsylvania, Forenede Stater, 17604-3555
    - Lancaster General Hospital
  - Langhorne, Pennsylvania, Forenede Stater, 19047
    - Saint Mary Regional Cancer Center
  - Media, Pennsylvania, Forenede Stater, 19063
    - Riddle Memorial Hospital
  - Paoli, Pennsylvania, Forenede Stater, 19301-1792
    - Cancer Center at Paoli Memorial Hospital
  - Philadelphia, Pennsylvania, Forenede Stater, 19111
    - Fox Chase Cancer Center
  - Philadelphia, Pennsylvania, Forenede Stater, 19141
    - Albert Einstein Cancer Center
  - Philadelphia, Pennsylvania, Forenede Stater, 19143
    - Mercy Hospital of Philadelphia
  - Philadelphia, Pennsylvania, Forenede Stater, 19107-5541
    - Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
  - Philadelphia, Pennsylvania, Forenede Stater, 19104-4283
    - Abramson Cancer Center at University of Pennsylvania Medical Center
  - Philadelphia, Pennsylvania, Forenede Stater, 19107
    - Pennsylvania Oncology Hematology Associates
  - Philadelphia, Pennsylvania, Forenede Stater, 19114
    - Frankford Hospital
  - Philadelphia, Pennsylvania, Forenede Stater, 19118
    - Chestnut Hill Healthcare
  - Philadelphia, Pennsylvania, Forenede Stater, 19140
    - Fox Chase - Temple Cancer Center
  - Pittsburgh, Pennsylvania, Forenede Stater, 15212-4772
    - Allegheny General Hospital
  - Pittsburgh, Pennsylvania, Forenede Stater, 15213-3489
    - Hillman Cancer Center at University of Pittsburgh Cancer Institute
  - Pottstown, Pennsylvania, Forenede Stater, 19464
    - Pottstown Memorial Regional Cancer Center
  - Reading, Pennsylvania, Forenede Stater, 19612-6052
    - Reading Hospital and Medical Center
  - Sellersville, Pennsylvania, Forenede Stater, 18960
    - Grand View Hospital
  - Upland, Pennsylvania, Forenede Stater, 19013
    - Crozer-Chester Medical Center
  - West Chester, Pennsylvania, Forenede Stater, 19380
    - Chester County Hospital
  - Wynnewood, Pennsylvania, Forenede Stater, 19096
    - Lankenau Cancer Center at Lankenau Hospital
  - York, Pennsylvania, Forenede Stater, 17403
    - Wellspan Health - York Cancer Center
- Rhode Island
  - Providence, Rhode Island, Forenede Stater, 02903
    - Rhode Island Hospital
- South Carolina
  - Anderson, South Carolina, Forenede Stater, 29621
    - AnMed Health
  - Charleston, South Carolina, Forenede Stater, 29425
    - Hollings Cancer Center at Medical University of South Carolina
  - Charleston, South Carolina, Forenede Stater, 29401
    - Roper St. Francis Healthcare - Roper Hospital
  - Columbia, South Carolina, Forenede Stater, 29203
    - Palmetto Richland Memorial Hospital
  - Florence, South Carolina, Forenede Stater, 29501
    - McLeod Regional Medical Center
  - Greenville, South Carolina, Forenede Stater, 29601
    - Cancer Centers of the Carolinas - Eastside
  - Spartanburg, South Carolina, Forenede Stater, 29303
    - CCOP - Upstate Carolina
- South Dakota
  - Rapid City, South Dakota, Forenede Stater, 57701
    - Rapid City Regional Hospital
  - Sioux Falls, South Dakota, Forenede Stater, 57104
    - CCOP - Sioux Community Cancer Consortium
- Tennessee
  - Kingsport, Tennessee, Forenede Stater, 37662
    - Wellmont Holston Valley Hospital and Medical Center
  - Knoxville, Tennessee, Forenede Stater, 37916
    - Thompson Cancer Survival Center
  - Knoxville, Tennessee, Forenede Stater, 37920-2911
    - U.T. Cancer Institute at University of Tennessee Medical Center
  - Memphis, Tennessee, Forenede Stater, 38117
    - Baptist Cancer Institute - Memphis at Baptist Memorial Hospital - Memphis
  - Nashville, Tennessee, Forenede Stater, 37208-3599
    - MBCCOP - Meharry Medical College - Nashville
  - Nashville, Tennessee, Forenede Stater, 37232-6838
    - Vanderbilt-Ingram Cancer Center at Vanderbilt Medical Center
- Texas
  - Abilene, Texas, Forenede Stater, 79601-2316
    - Hendrick Cancer Center
  - Amarillo, Texas, Forenede Stater, 79106
    - Harrington Cancer Center
  - Beaumont, Texas, Forenede Stater, 77701
    - Julie and Ben Rogers Cancer Center
  - Dallas, Texas, Forenede Stater, 75231
    - Presbyterian Hospital of Dallas
  - Dallas, Texas, Forenede Stater, 75235-9154
    - Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas
  - Dallas, Texas, Forenede Stater, 75246
    - Charles A. Sammons Cancer Center
  - Dallas, Texas, Forenede Stater, 75265-5999
    - Methodist Dallas Medical Center
  - El Paso, Texas, Forenede Stater, 79902
    - Providence Memorial Hospital
  - Fort Worth, Texas, Forenede Stater, 76104
    - Harris Methodist Fort Worth
  - Houston, Texas, Forenede Stater, 77030
    - Baylor College of Medicine
  - Houston, Texas, Forenede Stater, 77030-4009
    - University of Texas - MD Anderson Cancer Center
  - Houston, Texas, Forenede Stater, 77030
    - Texas Cancer Institute at St. Luke's Episcopal Hospital
  - Irving, Texas, Forenede Stater, 75061
    - Baylor Medical Center at Garland
  - Lackland Air Force Base, Texas, Forenede Stater, 78236-5300
    - Wilford Hall Medical Center
  - Laredo, Texas, Forenede Stater, 78041
    - Sanchez Cancer Center
  - Lubbock, Texas, Forenede Stater, 79410-1894
    - Joe Arrington Cancer Research and Treatment Center
  - Lubbock, Texas, Forenede Stater, 79415
    - Southwest Cancer and Research Center at University Medical Center
  - Lufkin, Texas, Forenede Stater, 75902
    - Memorial Health System of East Texas
  - Richardson, Texas, Forenede Stater, 75080
    - Baylor/Richardson Cancer Center
  - San Antonio, Texas, Forenede Stater, 78284-7811
    - University of Texas Health Science Center at San Antonio
  - Temple, Texas, Forenede Stater, 76508
    - CCOP - Scott and White Hospital
  - Tyler, Texas, Forenede Stater, 75708
    - University of Texas Health Center at Tyler
- Utah
  - Salt Lake City, Utah, Forenede Stater, 84112
    - Huntsman Cancer Institute
- Vermont
  - Bennington, Vermont, Forenede Stater, 05201
    - Green Mountain Oncology Group
  - Bennington, Vermont, Forenede Stater, 05201
    - Southwestern Vermont Regional Cancer Center
  - Berlin, Vermont, Forenede Stater, 05602
    - Mountainview Medical
  - Burlington, Vermont, Forenede Stater, 05401-3498
    - Vermont Cancer Center at University of Vermont
  - Rutland, Vermont, Forenede Stater, 05701
    - Community Cancer Center at Rutland Regional Medical Center
- Virginia
  - Charlottesville, Virginia, Forenede Stater, 22901
    - Martha Jefferson Hospital
  - Danville, Virginia, Forenede Stater, 24541
    - Cancer Center of the Piedmont, Inc.
  - Danville, Virginia, Forenede Stater, 24541
    - Danville Hematology and Oncology, Incorporated
  - Newport News, Virginia, Forenede Stater, 23606
    - Virginia Oncology Associates - Newport News
  - Richmond, Virginia, Forenede Stater, 23298-0037
    - MBCCOP - Massey Cancer Center
  - Richmond, Virginia, Forenede Stater, 23229
    - Henrico Doctors' Hospital - Parham Campus
  - Roanoke, Virginia, Forenede Stater, 24014
    - Oncology and Hematology Associates of Southwest Virginia, Inc.
- Washington
  - Bellingham, Washington, Forenede Stater, 98225
    - St. Joseph Hospital Community Cancer Center
  - Bremerton, Washington, Forenede Stater, 98310
    - Olympic Hematology and Oncology
  - Everett, Washington, Forenede Stater, 98258-0000
    - Flynn Cancer Center at Providence Everett Medical Center - Pacific Campus
  - Seattle, Washington, Forenede Stater, 98101
    - CCOP - Virginia Mason Research Center
  - Seattle, Washington, Forenede Stater, 98109-1024
    - Fred Hutchinson Cancer Research Center
  - Seattle, Washington, Forenede Stater, 98104
    - Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
  - Spokane, Washington, Forenede Stater, 99207
    - Cancer Care Northwest - Spokane North
  - Spokane, Washington, Forenede Stater, 99220
    - Rockwood Clinic P.S.
  - Tacoma, Washington, Forenede Stater, 98405-0986
    - CCOP - Northwest
  - Yakima, Washington, Forenede Stater, 89802
    - Yakima Regional Cancer Care Center
- West Virginia
  - Charleston, West Virginia, Forenede Stater, 25304-1297
    - David Lee Cancer Center at Charleston Area Medical Center
  - Parkersburg, West Virginia, Forenede Stater, 26102
    - Camden-Clark Memorial Hospital
- Wisconsin
  - La Crosse, Wisconsin, Forenede Stater, 54601
    - Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center
  - Madison, Wisconsin, Forenede Stater, 53792-6164
    - University of Wisconsin Comprehensive Cancer Center
  - Marshfield, Wisconsin, Forenede Stater, 54449
    - CCOP - Marshfield Clinic Research Foundation
  - Milwaukee, Wisconsin, Forenede Stater, 53226
    - Medical College of Wisconsin Cancer Center
  - Milwaukee, Wisconsin, Forenede Stater, 53201-0342
    - Aurora Sinai Medical Center
  - Milwaukee, Wisconsin, Forenede Stater, 53215
    - Oncology Alliance, S.C.
  - Waukesha, Wisconsin, Forenede Stater, 53188
    - Waukesha Memorial Hospital Regional Cancer Center
  - Wausau, Wisconsin, Forenede Stater, 54401
    - UW Cancer Center Wausau Hospital
Puerto Rico
- - San Juan, Puerto Rico, 00927-5800
    - MBCCOP - San Juan

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

35 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Køn, der er berettiget til at studere

Kvinde

Beskrivelse

SYGDOMS KARAKTERISTIKA:

Postmenopausale kvinder med øget risiko for at udvikle invasiv brystkræft, som opfylder et af følgende kriterier:
- Mindst 12 måneder siden spontan menstruationsblødning
- Tidligere dokumenteret hysterektomi og bilateral salpingo-ooforektomi
- Mindst 55 år med forudgående hysterektomi med eller uden oophorektomi
- Alder 35 til 54 med en tidligere hysterektomi uden oophorektomi ELLER med en ukendt status for æggestokke med dokumenteret follikelstimulerende hormonniveau, der viser forhøjet postmenopausalt område
Histologisk bekræftet lobulært karcinom in situ kun behandlet ved lokal excision ELLER en forventet minimum 5 års sandsynlighed for invasiv brystkræft på mindst 1,66 %, ved brug af risikovurderingsprofil for brystkræft
Ingen kliniske tegn på malignitet ved fysisk undersøgelse inden for de seneste 180 dage
Ingen tegn på mistænkelig eller ondartet sygdom på bilateral mammografi inden for det seneste år
Ingen bilateral eller unilateral profylaktisk mastektomi
Ingen tidligere invasiv brystkræft eller intraduktalt karcinom in situ
Hormonreceptorstatus:
- Ikke specificeret

PATIENT KARAKTERISTIKA:

Alder:

35 og derover

Køn:

Kvinde

Menopausal status:

Se Sygdomskarakteristika

Ydeevnestatus:

Ingen begrænset normal aktivitet i en betydelig del af hver dag

Forventede levealder:

Mindst 10 år

Hæmatopoietisk:

Granulocyttal mindst 1.500/mm^3
Fuldstændig blodtælling og differentiel normal
Blodpladetal normalt

Hepatisk:

SGOT eller SGPT normalt
Bilirubin normalt
Alkalisk fosfatase normal

Nyre:

Kreatinin normalt

Kardiovaskulær:

Ingen cerebral vaskulær ulykke, forbigående iskæmisk anfald, atrieflimren eller ukontrolleret hypertension
Ingen dyb venetrombose

Lunge:

Ingen lungeemboli

Andet:

Ingen anden tidligere malignitet inden for de seneste 5 år undtagen basalcelle- eller pladecellehudkræft eller carcinom in situ i livmoderhalsen
Ingen samtidig ikke-malign sygdom, der ville udelukke administration af tamoxifen eller raloxifen
Ingen klinisk depression, psykiatrisk tilstand eller vanedannende lidelse
Ingen ukontrolleret diabetes

FORUDSÆTNING SAMTYDLIG TERAPI:

Biologisk terapi:

Ikke specificeret

Kemoterapi:

Ikke specificeret

Endokrin terapi:

Mindst 3 måneder siden tidligere østrogen- eller progesteron-erstatningsterapi, orale præventionsmidler, androgener, luteiniserende hormon-frigivende hormonanaloger, prolaktinhæmmere eller antiandrogener
Mindst 3 måneder siden tidligere tamoxifen, raloxifen eller andre selektive østrogenreceptormodulatorer af mindre end 3 måneders varighed
Samtidig Estring tilladt

Strålebehandling:

Ingen forudgående bryststrålebehandling

Kirurgi:

Se Sygdomskarakteristika

Andet:

Ingen tidligere systemisk adjuverende behandling for brystkræft
Ingen anden deltagelse i et kræftforebyggende eller osteoporoseforebyggende studie, der involverer farmakologiske indgreb(er)
- NSABP-P-1-patienter, der fik placebo, er kvalificerede
Ingen samtidig warfarin eller kolestyramin
Samtidig calcitonin eller ikke-hormonel medicin (f.eks. cholecalciferol, fluorid eller bisfosfonater) tilladt

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Forebyggelse
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Dobbelt

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Aktiv komparator: Gruppe 1 Tamoxifen og placebo	Medicin: Tamoxifen 20 mg/dag plus placebo i 5 år
Eksperimentel: Gruppe 2 Raloxifen og placebo	Medicin: Raloxifen 60 mg/dag plus placebo i 5 år

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Forekomst af invasiv brystkræft; overlegenheden af en af terapierne. Tidsramme: Tid fra randomisering til forekomsten af invasiv brystkræft.	Bestem, hvilket af følgende er sandt: sammenlignet med tamoxifen, reducerer raloxifen signifikant hyppigheden af invasiv brystkræft; sammenlignet med raloxifen reducerer tamoxifen signifikant hyppigheden af invasiv brystkræft; eller den statistiske overlegenhed af en af behandlingerne kan ikke påvises, og valget af terapi bør baseres på fordele/risiko-overvejelser.	Tid fra randomisering til forekomsten af invasiv brystkræft.

Sekundære resultatmål

Resultatmål	Tidsramme
Effekt af undersøgelsesterapierne på forekomsten af intraduktalt karcinom in situ (DCIS) eller lobulært karcinom in situ (LCIS). Tidsramme: Tid fra randomisering til forekomsten af DCIS eller LCIS.	Tid fra randomisering til forekomsten af DCIS eller LCIS.
Effekt af undersøgelsesterapierne på forekomsten af endometriecancer. Tidsramme: Tid fra randomisering til forekomsten af endometriecancer.	Tid fra randomisering til forekomsten af endometriecancer.
Effekt af undersøgelsesterapierne på forekomsten af iskæmisk hjertesygdom. Tidsramme: Tid fra randomisering til forekomsten af iskimisk hjertesygdom.	Tid fra randomisering til forekomsten af iskimisk hjertesygdom.
Effekt af undersøgelsesterapierne på forekomsten af brud på hoften, rygsøjlen eller Colles' brud på håndleddet. Tidsramme: Tid fra randomisering til forekomsten af brud på hoften, rygsøjlen eller Colles' brud på håndleddet.	Tid fra randomisering til forekomsten af brud på hoften, rygsøjlen eller Colles' brud på håndleddet.
Effekt af undersøgelsesterapierne på toksiciteten og bivirkningerne af hver terapi. Tidsramme: Forekomster af protokoldefinerede toksiciteter og bivirkninger.	Forekomster af protokoldefinerede toksiciteter og bivirkninger.
Effekt af undersøgelsesterapierne på deltagernes livskvalitet. Tidsramme: præ-entry, hver 6. måned i 5 år, og derefter årligt efter 5 år efter randomisering.	præ-entry, hver 6. måned i 5 år, og derefter årligt efter 5 år efter randomisering.

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

NSABP Foundation Inc

Samarbejdspartnere

National Cancer Institute (NCI)

Eli Lilly and Company

AstraZeneca

Efterforskere

Studiestol: Norman Wolmark, MD, NSABP Foundation Inc

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Goetz MP, Schaid DJ, Wickerham DL, Safgren S, Mushiroda T, Kubo M, Batzler A, Costantino JP, Vogel VG, Paik S, Carlson EE, Flockhart DA, Wolmark N, Nakamura Y, Weinshilboum RM, Ingle JN, Ames MM. Evaluation of CYP2D6 and efficacy of tamoxifen and raloxifene in women treated for breast cancer chemoprevention: results from the NSABP P1 and P2 clinical trials. Clin Cancer Res. 2011 Nov 1;17(21):6944-51. doi: 10.1158/1078-0432.CCR-11-0860. Epub 2011 Aug 31. Erratum In: Clin Cancer Res. 2012 Jun 15;18(12):3491.
Cronin WM, Cecchini RS, Wickerham DL, et al.: Factors associated with participant adherence in the NSABP Study of Tamoxifen and Raloxifene (STAR). [Abstract] J Clin Oncol 26 (Suppl 15): A-6518, 2008.
Land SR, Ritter MW, Costantino JP, Julian TB, Cronin WM, Haile SR, Wolmark N, Ganz PA. Compliance with patient-reported outcomes in multicenter clinical trials: methodologic and practical approaches. J Clin Oncol. 2007 Nov 10;25(32):5113-20. doi: 10.1200/JCO.2007.12.1749.
Gradishar WJ, Cella D. Selective estrogen receptor modulators and prevention of invasive breast cancer. JAMA. 2006 Jun 21;295(23):2784-6. doi: 10.1001/jama.295.23.jed60037. Epub 2006 Jun 5. No abstract available.
Vogel VG. The NSABP Study of Tamoxifen and Raloxifene (STAR) trial. Expert Rev Anticancer Ther. 2009 Jan;9(1):51-60. doi: 10.1586/14737140.9.1.51. Erratum In: Expert Rev Anticancer Ther. 2009 Mar;9(3):388.
Wickerham DL, Costantino JP, Vogel VG, Cronin WM, Cecchini RS, Ford LG, Wolmark N. The use of tamoxifen and raloxifene for the prevention of breast cancer. Recent Results Cancer Res. 2009;181:113-9. doi: 10.1007/978-3-540-69297-3_12.
Ganz PA, Land SR, Wickerham DL, et al.: The Study of Tamoxifen and Raloxifene (STAR): Change in patient-reported outcomes (PROs) after the end of treatment. [Abstract] J Clin Oncol 25 (Suppl 18): A-1506, 2007.
Ganz PA, Land SR, Wickerham DL, et al.: The study of tamoxifen and raloxifene (STAR): first report of patient-reported outcomes (PROs) from the NSABP P-2 breast cancer prevention study. [Abstract] J Clin Oncol 24 (Suppl 18): A-LBA561, 2006.
Land SR, Wickerham DL, Costantino JP, Ritter MW, Vogel VG, Lee M, Pajon ER, Wade JL 3rd, Dakhil S, Lockhart JB Jr, Wolmark N, Ganz PA. Patient-reported symptoms and quality of life during treatment with tamoxifen or raloxifene for breast cancer prevention: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. JAMA. 2006 Jun 21;295(23):2742-51. doi: 10.1001/jama.295.23.joc60075. Epub 2006 Jun 5. Erratum In: JAMA. 2007 Sep 5;298(9):973.
Vogel VG, Costantino JP, Wickerham DL, et al.: The effects of tamoxifen versus raloxifene on the risk of developing noninvasive breast cancer in the NSABP study of tamoxifen and raloxifene (STAR) P-2 trial. [Abstract] Breast Cancer Res Treat 100 (Suppl 1): A-33, S16, 2006.
Vogel VG, Costantino JP, Wickerham DL, Cronin WM, Cecchini RS, Atkins JN, Bevers TB, Fehrenbacher L, Pajon ER Jr, Wade JL 3rd, Robidoux A, Margolese RG, James J, Lippman SM, Runowicz CD, Ganz PA, Reis SE, McCaskill-Stevens W, Ford LG, Jordan VC, Wolmark N; National Surgical Adjuvant Breast and Bowel Project (NSABP). Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. JAMA. 2006 Jun 21;295(23):2727-41. doi: 10.1001/jama.295.23.joc60074. Epub 2006 Jun 5. Erratum In: JAMA. 2006 Dec 27;296(24):2926. JAMA. 2007 Sep 5;298(9):973.
McCaskill-Stevens W, Wilson JW, Cook ED, Edwards CL, Gibson RV, McElwain DL, Figueroa-Moseley CD, Paskett ED, Roberson NL, Wickerham DL, Wolmark N. National Surgical Adjuvant Breast and Bowel Project Study of Tamoxifen and Raloxifene trial: advancing the science of recruitment and breast cancer risk assessment in minority communities. Clin Trials. 2013 Apr;10(2):280-91. doi: 10.1177/1740774512470315. Epub 2013 Jan 18.
Cecchini RS, Costantino JP, Cauley JA, Cronin WM, Wickerham DL, Land SR, Weissfeld JL, Wolmark N. Body mass index and the risk for developing invasive breast cancer among high-risk women in NSABP P-1 and STAR breast cancer prevention trials. Cancer Prev Res (Phila). 2012 Apr;5(4):583-92. doi: 10.1158/1940-6207.CAPR-11-0482. Epub 2012 Feb 7.
Vogel VG, Costantino JP, Wickerham DL, Cronin WM, Cecchini RS, Atkins JN, Bevers TB, Fehrenbacher L, Pajon ER, Wade JL 3rd, Robidoux A, Margolese RG, James J, Runowicz CD, Ganz PA, Reis SE, McCaskill-Stevens W, Ford LG, Jordan VC, Wolmark N; National Surgical Adjuvant Breast and Bowel Project. Update of the National Surgical Adjuvant Breast and Bowel Project Study of Tamoxifen and Raloxifene (STAR) P-2 Trial: Preventing breast cancer. Cancer Prev Res (Phila). 2010 Jun;3(6):696-706. doi: 10.1158/1940-6207.CAPR-10-0076. Epub 2010 Apr 19.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart

1. maj 1999

Primær færdiggørelse (Faktiske)

1. december 2005

Studieafslutning (Faktiske)

1. august 2012

Datoer for studieregistrering

Først indsendt

1. november 1999

Først indsendt, der opfyldte QC-kriterier

26. januar 2003

Først opslået (Skøn)

27. januar 2003

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Skøn)

6. oktober 2015

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

5. oktober 2015

Sidst verificeret

1. oktober 2015

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

brystkræft

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

NSABP P-2
CDR0000067081

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

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