- ICH GCP
- US Clinical Trials Registry
- Klinisk forsøg NCT00008385
Selen til forebyggelse af tumorvækst hos patienter med tidligere resekeret fase I ikke-småcellet lungekræft
Fase III kemopræventionsforsøg med selentilskud hos personer med resekeret fase I ikke-småcellet lungekræft
RATIONALE: Kemoforebyggende terapi er brugen af visse lægemidler for at forsøge at forhindre udvikling eller gentagelse af kræft. Det vides endnu ikke, om selen er effektivt til at forhindre væksten af nye tumorer hos patienter med tidligere resekeret ikke-småcellet lungekræft.
FORMÅL: Dette randomiserede fase III-forsøg studerer selen for at se, hvor godt det virker sammenlignet med placebo til at forhindre udviklingen af sekundære primære lungetumorer hos patienter, der har gennemgået en operation for at fjerne fase I ikke-småcellet lungecancer.
Studieoversigt
Detaljeret beskrivelse
MÅL:
Primært mål:
- Bestem effektiviteten af selen med hensyn til at reducere forekomsten af sekundære primære lungetumorer hos deltagere med tidligere resekeret fase I ikke-småcellet lungecancer.
Sekundære mål:
- Evaluer den kvalitative og kvantitative toksicitet af selen hos disse patienter.
- Sammenlign forekomsten af specifikke kræftformer, dødelighed af kræft og den samlede overlevelse af deltagere behandlet med selen i forhold til dem, der blev behandlet med placebo.
OVERSIGT: Dette er en randomiseret, dobbeltblindet, placebokontrolleret, multicenterundersøgelse. Deltagerne er stratificeret efter rygestatus (aktivt med at ryge eller stoppet for mindre end 1 år siden vs. stoppet for mindst 1 år siden vs. aldrig røget eller ikke mere end 100 cigaretter nogensinde), køn og stadium og tidligere behandling (stadie IA vs. stadium IB med tidligere behandling versus stadium IB uden tidligere behandling). Deltagerne randomiseres i forholdet 1:2 til arm I og arm II.
- Arm I: Deltagerne får en oral gærplacebo som i arm II.
- Arm II: Deltagerne modtager oral selengær dagligt i 6 måneder. Behandlingen gentages hver 6. måned i 8 forløb i i alt 4 år i fravær af uacceptabel toksicitet.
Deltagerne følges årligt (hver 12. måned) i 10 år.
PROJEKTERET TILSLUTNING: I alt 1.960 deltagere vil blive akkumuleret til denne undersøgelse inden for 4 år.
Undersøgelsestype
Tilmelding (Faktiske)
Fase
- Fase 3
Kontakter og lokationer
Studiesteder
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Quebec, Canada, G1V 4G5
- L'Hopital Laval
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Alberta
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Calgary, Alberta, Canada, T2N 4N2
- Tom Baker Cancer Centre - Calgary
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British Columbia
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Kelowna, British Columbia, Canada, V1Y 5L3
- British Columbia Cancer Agency - Centre for the Southern Interior
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Manitoba
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Winnipeg, Manitoba, Canada, R3E 0V9
- CancerCare Manitoba
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New Brunswick
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Saint John, New Brunswick, Canada, E2L 4L2
- Saint John Regional Hospital
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Nova Scotia
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Halifax, Nova Scotia, Canada, B3H 1V7
- Nova Scotia Cancer Centre
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Ontario
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Hamilton, Ontario, Canada, L8V 5C2
- Margaret and Charles Juravinski Cancer Centre
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Hamilton, Ontario, Canada, L8N 4A6
- St. Joseph's Hospital - Charlton Campus
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Kingston, Ontario, Canada, K7L 5P9
- Cancer Centre of Southeastern Ontario at Kingston General Hospital
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London, Ontario, Canada, N6A 4L6
- London Regional Cancer Program at London Health Sciences Centre
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Ottawa, Ontario, Canada, K1H 8L6
- Ottawa Hospital Regional Cancer Centre - General Campus
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Sault Ste. Marie, Ontario, Canada, P6A 2C4
- Algoma District Cancer Program at Sault Area Hospital
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Sudbury, Ontario, Canada, P3E 5J1
- Northeastern Ontario Regional Cancer Centre
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Thunder Bay, Ontario, Canada, P7B 6V4
- Cancer Care Program at Thunder Bay Regional Health Sciences
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Toronto, Ontario, Canada, M5G 2M9
- Princess Margaret Hospital
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Toronto, Ontario, Canada, M9C 1A5
- Trillium Health Centre - Mississauga Site
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Quebec
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Montreal, Quebec, Canada, H2L 4M1
- Hopital Notre-Dame du CHUM
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Alabama
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Mobile, Alabama, Forenede Stater, 36604
- MBCCOP - Gulf Coast
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Mobile, Alabama, Forenede Stater, 36608
- Providence Cancer Center at Providence Hospital
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Arizona
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Phoenix, Arizona, Forenede Stater, 85013
- Arizona Oncology Services Foundation
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Scottsdale, Arizona, Forenede Stater, 85259-5499
- Mayo Clinic Scottsdale
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Scottsdale, Arizona, Forenede Stater, 85260
- Virginia G. Piper Cancer Center at Scottsdale Healthcare - Shea
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Scottsdale, Arizona, Forenede Stater, 85251
- Virginia G. Piper Cancer Center at Scottsdale Healthcare - Osborn
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Arkansas
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Bentonville, Arkansas, Forenede Stater, 72712
- Highlands Oncology Group - Springdale
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Little Rock, Arkansas, Forenede Stater, 72205
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences
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California
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Castro Valley, California, Forenede Stater, 94546
- East Bay Radiation Oncology Center
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Castro Valley, California, Forenede Stater, 94546
- Eden Medical Center
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Fairfield, California, Forenede Stater, 94533
- North Bay Cancer Center
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La Jolla, California, Forenede Stater, 92093-0658
- Rebecca and John Moores UCSD Cancer Center
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Los Angeles, California, Forenede Stater, 90048
- Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center
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Martinez, California, Forenede Stater, 94553-3156
- Contra Costa Regional Medical Center
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Marysville, California, Forenede Stater, 95901
- Tibotec Therapeutics - Division of Ortho Biotech Products, LP
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Modesto, California, Forenede Stater, 95355
- Memorial Medical Center
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Mountain View, California, Forenede Stater, 94040
- El Camino Hospital Cancer Center
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Oakland, California, Forenede Stater, 94609
- Alta Bates Summit Medical Center - Summit Campus
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Oakland, California, Forenede Stater, 94602
- Highland General Hospital
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Oakland, California, Forenede Stater, 94609
- Larry G Strieff MD Medical Corporation
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Oakland, California, Forenede Stater, 94609
- CCOP - Bay Area Tumor Institute
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Oakland, California, Forenede Stater, 94609
- Bay Area Breast Surgeons, Incorporated
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Oakland, California, Forenede Stater, 94609
- Tom K Lee, Incorporated
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Palo Alto, California, Forenede Stater, 94304
- Veterans Affairs Medical Center - Palo Alto
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Pleasanton, California, Forenede Stater, 94588
- Valley Care Medical Center
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Pleasanton, California, Forenede Stater, 94588
- Valley Medical Oncology Consultants - Pleasanton
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Pomona, California, Forenede Stater, 91767
- Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center
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Rancho Mirage, California, Forenede Stater, 92270
- Lucy Curci Cancer Center at Eisenhower Memorial Hospital and Medical Center
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Sacramento, California, Forenede Stater, 95819
- Mercy General Hospital
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Sacramento, California, Forenede Stater, 95817
- University of California Davis Cancer Center
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San Diego, California, Forenede Stater, 92120
- Kaiser Permanente Medical Office -Vandever Medical Office
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San Pablo, California, Forenede Stater, 94806
- Doctors Medical Center - San Pablo Campus
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Stanford, California, Forenede Stater, 94305-5824
- Stanford Cancer Center
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Truckee, California, Forenede Stater, 96161
- Tahoe Forest Cancer Center
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Colorado
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Aurora, Colorado, Forenede Stater, 80012
- Aurora Presbyterian Hospital
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Boulder, Colorado, Forenede Stater, 80301-9019
- Boulder Community Hospital
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Colorado Springs, Colorado, Forenede Stater, 80933
- Penrose Cancer Center at Penrose Hospital
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Denver, Colorado, Forenede Stater, 80210
- Porter Adventist Hospital
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Denver, Colorado, Forenede Stater, 80220
- Rose Medical Center
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Denver, Colorado, Forenede Stater, 80218
- Presbyterian - St. Luke's Medical Center
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Denver, Colorado, Forenede Stater, 80204
- St. Anthony Central Hospital
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Denver, Colorado, Forenede Stater, 80218
- St. Joseph Hospital
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Denver, Colorado, Forenede Stater, 80224-2522
- CCOP - Colorado Cancer Research Program
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Englewood, Colorado, Forenede Stater, 80110
- Swedish Medical Center
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Fort Collins, Colorado, Forenede Stater, 80524
- Poudre Valley Hospital
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Fort Collins, Colorado, Forenede Stater, 80528
- Front Range Cancer Specialists
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Grand Junction, Colorado, Forenede Stater, 81502
- St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
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Greeley, Colorado, Forenede Stater, 80631
- North Colorado Medical Center
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Lone Tree, Colorado, Forenede Stater, 80124
- Sky Ridge Medical Center
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Longmont, Colorado, Forenede Stater, 80501
- Hope Cancer Care Center at Longmont United Hospital
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Loveland, Colorado, Forenede Stater, 80539
- McKee Medical Center
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Pueblo, Colorado, Forenede Stater, 81004
- St. Mary - Corwin Regional Medical Center
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Thornton, Colorado, Forenede Stater, 80229
- North Suburban Medical Center
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Wheat Ridge, Colorado, Forenede Stater, 80033
- Exempla Lutheran Medical Center
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Connecticut
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Danbury, Connecticut, Forenede Stater, 06810
- Praxair Cancer Center at Danbury Hospital
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Hartford, Connecticut, Forenede Stater, 06102-5037
- Helen and Harry Gray Cancer Center at Hartford Hospital
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New Haven, Connecticut, Forenede Stater, 06511
- Hospital of Saint Raphael
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Norwich, Connecticut, Forenede Stater, 06360
- Eastern Connecticut Hematology and Oncology Associates
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Torrington, Connecticut, Forenede Stater, 06790
- Connecticut Oncology & Hematology - Torrington
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Delaware
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Lewes, Delaware, Forenede Stater, 19958
- Tunnell Cancer Center at Beebe Medical Center
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Newark, Delaware, Forenede Stater, 19713
- CCOP - Christiana Care Health Services
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District of Columbia
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Washington, District of Columbia, Forenede Stater, 20307-5001
- Walter Reed Army Medical Center
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Florida
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Jacksonville, Florida, Forenede Stater, 32224
- Mayo Clinic - Jacksonville
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Pensacola, Florida, Forenede Stater, 32504
- Sacred Heart Cancer Center at Sacred Heart Hospital
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Pensacola, Florida, Forenede Stater, 32514
- West Florida Cancer Institute at West Florida Hospital - Pensacola
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Georgia
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Atlanta, Georgia, Forenede Stater, 30322
- Winship Cancer Institute of Emory University
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Atlanta, Georgia, Forenede Stater, 30309
- Piedmont Hospital
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Atlanta, Georgia, Forenede Stater, 30342-1611
- Northside Hospital Cancer Center
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Atlanta, Georgia, Forenede Stater, 30342-1701
- Saint Joseph's Hospital of Atlanta
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Atlanta, Georgia, Forenede Stater, 30342
- CCOP - Atlanta Regional
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Austell, Georgia, Forenede Stater, 30106
- WellStar Cobb Hospital
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Decatur, Georgia, Forenede Stater, 30033
- Charles B. Eberhart Cancer Center at DeKalb Medical Center
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Decatur, Georgia, Forenede Stater, 30033
- Veterans Affairs Medical Center - Atlanta (Decatur)
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Lawrenceville, Georgia, Forenede Stater, 30045
- Gwinnett Medical Center
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Marietta, Georgia, Forenede Stater, 30060
- Kennestone Cancer Center at Wellstar Kennestone Hospital
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Riverdale, Georgia, Forenede Stater, 30274-2600
- Southern Regional Medical Center
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Rome, Georgia, Forenede Stater, 30165
- Harbin Clinic Cancer Center - Medical Oncology
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Savannah, Georgia, Forenede Stater, 31405
- Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
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Valdosta, Georgia, Forenede Stater, 31603
- Pearlman Comprehensive Cancer Center at South Georgia Medical Center
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Hawaii
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'Aiea, Hawaii, Forenede Stater, 96701
- Kapiolani Medical Center at Pali Momi
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Honolulu, Hawaii, Forenede Stater, 96813
- Cancer Research Center of Hawaii
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Honolulu, Hawaii, Forenede Stater, 96826
- Kapiolani Medical Center for Women and Children
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Honolulu, Hawaii, Forenede Stater, 96813
- OnCare Hawaii, Incorporated - Lusitana
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Honolulu, Hawaii, Forenede Stater, 96813
- Queen's Cancer Institute at Queen's Medical Center
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Honolulu, Hawaii, Forenede Stater, 96813
- Straub Clinic and Hospital, Incorporated
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Honolulu, Hawaii, Forenede Stater, 96817
- Hawaii Medical Center - East
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Honolulu, Hawaii, Forenede Stater, 96817
- OnCare Hawaii, Incorporated - Kuakini
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Honolulu, Hawaii, Forenede Stater, 96859
- Tripler Army Medical Center
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Wailuku, Hawaii, Forenede Stater, 96793
- Maui Memorial Medical Center
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Wailuku, Hawaii, Forenede Stater, 96793
- Pacific Cancer Institute - Maui
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Idaho
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Boise, Idaho, Forenede Stater, 83706
- Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center
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Illinois
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Berwyn, Illinois, Forenede Stater, 60402
- Hematology Oncology Associates of Illinois - Berwyn
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Bloomington, Illinois, Forenede Stater, 61701
- Illinois CancerCare - Bloomington
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Bloomington, Illinois, Forenede Stater, 61701
- St. Joseph Medical Center
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Canton, Illinois, Forenede Stater, 61520
- Illinois CancerCare - Canton
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Canton, Illinois, Forenede Stater, 61520
- Graham Hospital
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Carthage, Illinois, Forenede Stater, 62321
- Memorial Hospital
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Carthage, Illinois, Forenede Stater, 62321
- Illinois CancerCare - Carthage
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Chicago, Illinois, Forenede Stater, 60611-3013
- Robert H. Lurie Comprehensive Cancer Center at Northwestern University
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Chicago, Illinois, Forenede Stater, 60612-7243
- University of Illinois Cancer Center
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Chicago, Illinois, Forenede Stater, 60611
- Hematology and Oncology Associates
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Chicago, Illinois, Forenede Stater, 60657
- Saint Joseph Hospital
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Chicago, Illinois, Forenede Stater, 60612-3785
- John H. Stroger, Jr. Hospital of Cook County
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Chicago, Illinois, Forenede Stater, 60612
- Veterans Affairs Medical Center - Chicago Westside Hospital
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Decatur, Illinois, Forenede Stater, 62526
- Decatur Memorial Hospital Cancer Care Institute
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Elgin, Illinois, Forenede Stater, 60120
- Sherman Hospital
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Elk Grove Village, Illinois, Forenede Stater, 60007
- Alexian Brothers Radiation Oncology
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Elmhurst, Illinois, Forenede Stater, 60126
- Elmhurst Memorial Hospital
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Eureka, Illinois, Forenede Stater, 61530
- Illinois CancerCare - Eureka
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Eureka, Illinois, Forenede Stater, 61530
- Eureka Community Hospital
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Evanston, Illinois, Forenede Stater, 60201-1781
- Evanston Hospital
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Galesburg, Illinois, Forenede Stater, 61401
- Illinois CancerCare - Galesburg
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Galesburg, Illinois, Forenede Stater, 61401
- Galesburg Cottage Hospital
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Galesburg, Illinois, Forenede Stater, 61401
- Galesburg Clinic, PC
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Harvey, Illinois, Forenede Stater, 60426
- Ingalls Cancer Care Center at Ingalls Memorial Hospital
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Havana, Illinois, Forenede Stater, 62644
- Mason District Hospital
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Havana, Illinois, Forenede Stater, 62644
- Illinois CancerCare - Havana
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Joliet, Illinois, Forenede Stater, 60435
- Joliet Oncology-Hematology Associates, Limited - West
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Joliet, Illinois, Forenede Stater, 60432
- Midwest Center for Hematology/Oncology
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Kewanee, Illinois, Forenede Stater, 61443
- Illinois CancerCare - Kewanee Clinic
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Libertyville, Illinois, Forenede Stater, 60048
- North Shore Oncology and Hematology Associates, Limited - Libertyville
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Macomb, Illinois, Forenede Stater, 61455
- Illinois CancerCare - Macomb
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Macomb, Illinois, Forenede Stater, 61455
- Mcdonough District Hospital
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Maywood, Illinois, Forenede Stater, 60153
- Cardinal Bernardin Cancer Center at Loyola University Medical Center
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Moline, Illinois, Forenede Stater, 61265
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Moline, Illinois, Forenede Stater, 61265
- Trinity Cancer Center at Trinity Medical Center - 7th Street Campus
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Monmouth, Illinois, Forenede Stater, 61462
- Illinois CancerCare - Monmouth
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Monmouth, Illinois, Forenede Stater, 61462
- OSF Holy Family Medical Center
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Naperville, Illinois, Forenede Stater, 60563
- La Grange Oncology Associates - Geneva
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Niles, Illinois, Forenede Stater, 60714
- Cancer Care and Hematology Specialists of Chicagoland - Niles
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Normal, Illinois, Forenede Stater, 61761
- Bromenn Regional Medical Center
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Normal, Illinois, Forenede Stater, 61761
- Community Cancer Center
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Normal, Illinois, Forenede Stater, 61761
- Illinois CancerCare - Community Cancer Center
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Ottawa, Illinois, Forenede Stater, 61350
- Community Hospital of Ottawa
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Ottawa, Illinois, Forenede Stater, 61350
- Oncology Hematology Associates of Central Illinois, PC - Ottawa
-
Pekin, Illinois, Forenede Stater, 61554
- Cancer Treatment Center at Pekin Hospital
-
Pekin, Illinois, Forenede Stater, 61603
- Illinois CancerCare - Pekin
-
Peoria, Illinois, Forenede Stater, 61636
- Methodist Medical Center of Illinois
-
Peoria, Illinois, Forenede Stater, 61614
- Proctor Hospital
-
Peoria, Illinois, Forenede Stater, 61637
- OSF St. Francis Medical Center
-
Peoria, Illinois, Forenede Stater, 61615
- CCOP - Illinois Oncology Research Association
-
Peoria, Illinois, Forenede Stater, 61615
- Oncology Hematology Associates of Central Illinois, PC - Peoria
-
Peru, Illinois, Forenede Stater, 61354
- Illinois CancerCare - Peru
-
Peru, Illinois, Forenede Stater, 61354
- Illinois Valley Community Hospital
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Princeton, Illinois, Forenede Stater, 61356
- Illinois CancerCare - Princeton
-
Rockford, Illinois, Forenede Stater, 61104-2315
- Swedish-American Regional Cancer Center
-
Skokie, Illinois, Forenede Stater, 60076
- Hematology Oncology Associates - Skokie
-
Spring Valley, Illinois, Forenede Stater, 61362
- Illinois CancerCare - Spring Valley
-
Spring Valley, Illinois, Forenede Stater, 61362
- St. Margaret's Hospital
-
Springfield, Illinois, Forenede Stater, 62781-0001
- Regional Cancer Center at Memorial Medical Center
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Indiana
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Beech Grove, Indiana, Forenede Stater, 46107
- St. Francis Hospital and Health Centers - Beech Grove Campus
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Elkhart, Indiana, Forenede Stater, 46515
- Elkhart General Hospital
-
Indianapolis, Indiana, Forenede Stater, 46202-5289
- Indiana University Melvin and Bren Simon Cancer Center
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Indianapolis, Indiana, Forenede Stater, 46202
- William N. Wishard Memorial Hospital
-
Indianapolis, Indiana, Forenede Stater, 46202
- Veterans Affairs Medical Center - Indianapolis
-
Kokomo, Indiana, Forenede Stater, 46904
- Howard Community Hospital
-
La Porte, Indiana, Forenede Stater, 46350
- Center for Cancer Therapy at LaPorte Hospital and Health Services
-
Richmond, Indiana, Forenede Stater, 47374
- Reid Hospital & Health Care Services
-
South Bend, Indiana, Forenede Stater, 46601
- Memorial Hospital of South Bend
-
South Bend, Indiana, Forenede Stater, 46601
- CCOP - Northern Indiana CR Consortium
-
South Bend, Indiana, Forenede Stater, 46617
- Saint Joseph Regional Medical Center
-
South Bend, Indiana, Forenede Stater, 46617
- South Bend Clinic
-
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Iowa
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Ames, Iowa, Forenede Stater, 50010
- McFarland Clinic, PC
-
Bettendorf, Iowa, Forenede Stater, 52722
-
Cedar Rapids, Iowa, Forenede Stater, 52402
- St. Luke's Hospital
-
Cedar Rapids, Iowa, Forenede Stater, 52403
- Cedar Rapids Oncology Associates
-
Cedar Rapids, Iowa, Forenede Stater, 52403
- Mercy Regional Cancer Center at Mercy Medical Center
-
Cedar Rapids, Iowa, Forenede Stater, 52402
- Iowa Blood and Cancer Care
-
Davenport, Iowa, Forenede Stater, 52803
- Genesis Regional Cancer Center at Genesis Medical Center
-
Mason City, Iowa, Forenede Stater, 50401
- Mercy Cancer Center at Mercy Medical Center - North Iowa
-
Ottumwa, Iowa, Forenede Stater, 52501
- McCreery Cancer Center at Ottumwa Regional
-
Sioux City, Iowa, Forenede Stater, 51101
- Siouxland Hematology-Oncology Associates, LLP
-
Sioux City, Iowa, Forenede Stater, 51104
- St. Luke's Regional Medical Center
-
Sioux City, Iowa, Forenede Stater, 51104
- Mercy Medical Center - Sioux City
-
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Kansas
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Anthony, Kansas, Forenede Stater, 67003
- Hospital District Sixth of Harper County
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Chanute, Kansas, Forenede Stater, 66720
- Cancer Center of Kansas, PA - Chanute
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Dodge City, Kansas, Forenede Stater, 67801
- Cancer Center of Kansas, PA - Dodge City
-
El Dorado, Kansas, Forenede Stater, 67042
- Cancer Center of Kansas, PA - El Dorado
-
Fort Scott, Kansas, Forenede Stater, 66701
- Cancer Center of Kansas - Fort Scott
-
Independence, Kansas, Forenede Stater, 67301
- Cancer Center of Kansas-Independence
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Kingman, Kansas, Forenede Stater, 67068
- Cancer Center of Kansas, PA - Kingman
-
Lawrence, Kansas, Forenede Stater, 66044
- Lawrence Memorial Hospital
-
Liberal, Kansas, Forenede Stater, 67901
- Southwest Medical Center
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Newton, Kansas, Forenede Stater, 67114
- Cancer Center of Kansas, PA - Newton
-
Overland Park, Kansas, Forenede Stater, 66209
- Menorah Medical Center
-
Parsons, Kansas, Forenede Stater, 67357
- Cancer Center of Kansas, PA - Parsons
-
Pratt, Kansas, Forenede Stater, 67124
- Cancer Center of Kansas, PA - Pratt
-
Salina, Kansas, Forenede Stater, 67042
- Cancer Center of Kansas, PA - Salina
-
Salina, Kansas, Forenede Stater, 67401
- Tammy Walker Cancer Center at Salina Regional Health Center
-
Shawnee Mission, Kansas, Forenede Stater, 66204
- Shawnee Mission Medical Center
-
Topeka, Kansas, Forenede Stater, 66606
- Cotton-O'Neil Cancer Center
-
Wellington, Kansas, Forenede Stater, 67152
- Cancer Center of Kansas, PA - Wellington
-
Wichita, Kansas, Forenede Stater, 67208
- Cancer Center of Kansas, PA - Medical Arts Tower
-
Wichita, Kansas, Forenede Stater, 67214
- Cancer Center of Kansas, PA - Wichita
-
Wichita, Kansas, Forenede Stater, 67214
- CCOP - Wichita
-
Wichita, Kansas, Forenede Stater, 67214
- Via Christi Cancer Center at Via Christi Regional Medical Center
-
Wichita, Kansas, Forenede Stater, 67208
- Associates in Womens Health, PA - North Review
-
Winfield, Kansas, Forenede Stater, 67156
- Cancer Center of Kansas, PA - Winfield
-
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Kentucky
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Madisonville, Kentucky, Forenede Stater, 42431
- Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins County
-
Owensboro, Kentucky, Forenede Stater, 42303
- Mitchell Memorial Cancer Center at Owensboro Medical Health System
-
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Louisiana
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Alexandria, Louisiana, Forenede Stater, 71315-3198
- Tulane Cancer Center Office of Clinical Research
-
Baton Rouge, Louisiana, Forenede Stater, 70809
- Ochsner Health Center - Bluebonnet
-
New Orleans, Louisiana, Forenede Stater, 70121
- CCOP - Ochsner
-
New Orleans, Louisiana, Forenede Stater, 70121
- Ochsner Cancer Institute at Ochsner Clinic Foundation
-
-
Maine
-
York, Maine, Forenede Stater, 03909
- York Hospital's Oncology Treatment Center
-
-
Maryland
-
Baltimore, Maryland, Forenede Stater, 21231-2410
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
-
Baltimore, Maryland, Forenede Stater, 21204
- Greater Baltimore Medical Center Cancer Center
-
Elkton, Maryland, Forenede Stater, 21921
- Union Hospital Cancer Program at Union Hospital
-
-
Massachusetts
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Boston, Massachusetts, Forenede Stater, 02118
- Boston University Cancer Research Center
-
Brighton, Massachusetts, Forenede Stater, 02135-2997
- Caritas St. Elizabeth's Medical Center
-
Hyannis, Massachusetts, Forenede Stater, 02601
- Cape Cod Hospital
-
Norwood, Massachusetts, Forenede Stater, 02062
- Caritas Norwood Hospital
-
Springfield, Massachusetts, Forenede Stater, 01199
- Baystate Regional Cancer Program at D'Amour Center for Cancer Care
-
-
Michigan
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Adrian, Michigan, Forenede Stater, 49221
- Hickman Cancer Center at Bixby Medical Center
-
Ann Arbor, Michigan, Forenede Stater, 48109-0942
- University of Michigan Comprehensive Cancer Center
-
Ann Arbor, Michigan, Forenede Stater, 48106-0995
- Saint Joseph Mercy Cancer Center
-
Ann Arbor, Michigan, Forenede Stater, 48106
- CCOP - Michigan Cancer Research Consortium
-
Battle Creek, Michigan, Forenede Stater, 49017
- Battle Creek Health System Cancer Care Center
-
Big Rapids, Michigan, Forenede Stater, 49307
- Mecosta County Medical Center
-
Dearborn, Michigan, Forenede Stater, 48123-2500
- Oakwood Cancer Center at Oakwood Hospital and Medical Center
-
Detroit, Michigan, Forenede Stater, 48201-1379
- Barbara Ann Karmanos Cancer Institute
-
Escanaba, Michigan, Forenede Stater, 49431
- Green Bay Oncology, Limited - Escanaba
-
Flint, Michigan, Forenede Stater, 48503
- Hurley Medical Center
-
Flint, Michigan, Forenede Stater, 48503
- Genesys Hurley Cancer Institute
-
Grand Rapids, Michigan, Forenede Stater, 49503
- Butterworth Hospital at Spectrum Health
-
Grand Rapids, Michigan, Forenede Stater, 49503
- CCOP - Grand Rapids
-
Grand Rapids, Michigan, Forenede Stater, 49503
- Lacks Cancer Center at Saint Mary's Health Care
-
Grosse Pointe Woods, Michigan, Forenede Stater, 48236
- Van Elslander Cancer Center at St. John Hospital and Medical Center
-
Iron Mountain, Michigan, Forenede Stater, 49801
- Dickinson County Healthcare System
-
Jackson, Michigan, Forenede Stater, 49201
- Foote Memorial Hospital
-
Kalamazoo, Michigan, Forenede Stater, 49007
- Bronson Methodist Hospital
-
Kalamazoo, Michigan, Forenede Stater, 49001
- Borgess Medical Center
-
Kalamazoo, Michigan, Forenede Stater, 49007-3731
- West Michigan Cancer Center
-
Lambertville, Michigan, Forenede Stater, 48144
- Haematology-Oncology Associates of Ohio and Michigan, PC
-
Lansing, Michigan, Forenede Stater, 48912-1811
- Sparrow Regional Cancer Center
-
Lansing, Michigan, Forenede Stater, 48910
- Breslin Cancer Center at Ingham Regional Medical Center
-
Livonia, Michigan, Forenede Stater, 48154
- St. Mary Mercy Hospital
-
Monroe, Michigan, Forenede Stater, 48162
- Community Cancer Center of Monroe
-
Monroe, Michigan, Forenede Stater, 48162
- Mercy Memorial Hospital - Monroe
-
Muskegon, Michigan, Forenede Stater, 49443
- Mercy General Health Partners
-
Pontiac, Michigan, Forenede Stater, 48341-2985
- St. Joseph Mercy Oakland
-
Port Huron, Michigan, Forenede Stater, 48060
- Mercy Regional Cancer Center at Mercy Hospital
-
Royal Oak, Michigan, Forenede Stater, 48073
- William Beaumont Hospital - Royal Oak Campus
-
Saginaw, Michigan, Forenede Stater, 48601
- Seton Cancer Institute at Saint Mary's - Saginaw
-
Saint Joseph, Michigan, Forenede Stater, 49085
- Lakeland Regional Cancer Care Center - St. Joseph
-
Traverse City, Michigan, Forenede Stater, 49684
- Munson Medical Center
-
Warren, Michigan, Forenede Stater, 48093
- St. John Macomb Hospital
-
Wyoming, Michigan, Forenede Stater, 49519
- Metro Health Hospital
-
-
Minnesota
-
Alexandria, Minnesota, Forenede Stater, 56308
-
Bemidji, Minnesota, Forenede Stater, 56601
- MeritCare Bemidji
-
Burnsville, Minnesota, Forenede Stater, 55337
- Fairview Ridges Hospital
-
Coon Rapids, Minnesota, Forenede Stater, 55433
- Mercy and Unity Cancer Center at Mercy Hospital
-
Duluth, Minnesota, Forenede Stater, 55805
- CCOP - Duluth
-
Duluth, Minnesota, Forenede Stater, 55805-1983
- Duluth Clinic Cancer Center - Duluth
-
Duluth, Minnesota, Forenede Stater, 55805
- Miller - Dwan Medical Center
-
Edina, Minnesota, Forenede Stater, 55435
- Fairview Southdale Hospital
-
Fridley, Minnesota, Forenede Stater, 55432
- Mercy and Unity Cancer Center at Unity Hospital
-
Hutchinson, Minnesota, Forenede Stater, 55350
- Hutchinson Area Health Care
-
Maplewood, Minnesota, Forenede Stater, 55109
- Minnesota Oncology Hematology, PA - Maplewood
-
Maplewood, Minnesota, Forenede Stater, 55109
- HealthEast Cancer Care at St. John's Hospital
-
Minneapolis, Minnesota, Forenede Stater, 55417
- Veterans Affairs Medical Center - Minneapolis
-
Minneapolis, Minnesota, Forenede Stater, 55407
- Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
-
Minneapolis, Minnesota, Forenede Stater, 55455
- Masonic Cancer Center at University of Minnesota
-
Minneapolis, Minnesota, Forenede Stater, 55415
- Hennepin County Medical Center - Minneapolis
-
Robbinsdale, Minnesota, Forenede Stater, 55422-2900
- Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
-
Rochester, Minnesota, Forenede Stater, 55905
- Mayo Clinic Cancer Center
-
Saint Cloud, Minnesota, Forenede Stater, 56303
- CentraCare Clinic - River Campus
-
Saint Cloud, Minnesota, Forenede Stater, 56303
- Coborn Cancer Center
-
Saint Louis Park, Minnesota, Forenede Stater, 55416
- CCOP - Metro-Minnesota
-
Saint Louis Park, Minnesota, Forenede Stater, 55416
- Park Nicollet Cancer Center
-
Saint Paul, Minnesota, Forenede Stater, 55102
- United Hospital
-
Saint Paul, Minnesota, Forenede Stater, 55101
- Regions Hospital Cancer Care Center
-
Shakopee, Minnesota, Forenede Stater, 55379
- St. Francis Cancer Center at St. Francis Medical Center
-
Waconia, Minnesota, Forenede Stater, 55387
- Ridgeview Medical Center
-
Willmar, Minnesota, Forenede Stater, 56201
- Willmar Cancer Center at Rice Memorial Hospital
-
Woodbury, Minnesota, Forenede Stater, 55125
- Minnesota Oncology Hematology, PA - Woodbury
-
-
Mississippi
-
Hattiesburg, Mississippi, Forenede Stater, 39401
- Hattiesburg Clinic, PA at Forrest General
-
-
Missouri
-
Kansas City, Missouri, Forenede Stater, 64131
- CCOP - Kansas City
-
Kansas City, Missouri, Forenede Stater, 64116
- North Kansas City Hospital
-
Kansas City, Missouri, Forenede Stater, 64132
- Research Medical Center
-
Kansas City, Missouri, Forenede Stater, 64108
- Truman Medical Center - Hospital Hill
-
Kansas City, Missouri, Forenede Stater, 64111
- Saint Luke's Cancer Institute at Saint Luke's Hospital
-
Kansas City, Missouri, Forenede Stater, 64114
- St. Joseph Medical Center
-
Liberty, Missouri, Forenede Stater, 64068
- Liberty Hospital
-
Saint Joseph, Missouri, Forenede Stater, 64506
- Heartland Regional Medical Center
-
Saint Louis, Missouri, Forenede Stater, 63136
- Christian Hospital Northeast Cancer Care Center
-
Springfield, Missouri, Forenede Stater, 65802
- CCOP - Cancer Research for the Ozarks
-
Springfield, Missouri, Forenede Stater, 65804
- St. John's Regional Health Center
-
-
Montana
-
Billings, Montana, Forenede Stater, 59101
- CCOP - Montana Cancer Consortium
-
Billings, Montana, Forenede Stater, 59101
- Hematology-Oncology Centers of the Northern Rockies - Billings
-
Billings, Montana, Forenede Stater, 59101
- Northern Rockies Radiation Oncology Center
-
Billings, Montana, Forenede Stater, 59101
- St. Vincent Healthcare Cancer Care Services
-
Billings, Montana, Forenede Stater, 59107-7000
- Billings Clinic - Downtown
-
Bozeman, Montana, Forenede Stater, 59715
- Bozeman Deaconess Cancer Center
-
Butte, Montana, Forenede Stater, 59701
- St. James Healthcare Cancer Care
-
Great Falls, Montana, Forenede Stater, 59405
- Great Falls Clinic - Main Facility
-
Great Falls, Montana, Forenede Stater, 59405
-
Great Falls, Montana, Forenede Stater, 59405-5309
- Big Sky Oncology
-
Great Falls, Montana, Forenede Stater, 59405
- Sletten Cancer Institute at Benefis Healthcare
-
Havre, Montana, Forenede Stater, 59501
- Northern Montana Hospital
-
Helena, Montana, Forenede Stater, 59601
- St. Peter's Hospital
-
Kalispell, Montana, Forenede Stater, 59901
- Kalispell Regional Medical Center
-
Kalispell, Montana, Forenede Stater, 59901
- Glacier Oncology, PLLC
-
Kalispell, Montana, Forenede Stater, 59901
- Kalispell Medical Oncology at KRMC
-
Missoula, Montana, Forenede Stater, 59801
- Community Medical Center
-
Missoula, Montana, Forenede Stater, 59804
- Guardian Oncology and Center for Wellness
-
Missoula, Montana, Forenede Stater, 59807-7877
- Montana Cancer Specialists at Montana Cancer Center
-
Missoula, Montana, Forenede Stater, 59807
- Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
-
-
Nebraska
-
Kearney, Nebraska, Forenede Stater, 68848-1990
- Good Samaritan Cancer Center at Good Samaritan Hospital
-
Lincoln, Nebraska, Forenede Stater, 68510
- Cancer Resource Center - Lincoln
-
Omaha, Nebraska, Forenede Stater, 68106
- CCOP - Missouri Valley Cancer Consortium
-
Omaha, Nebraska, Forenede Stater, 68122
- Immanuel Medical Center
-
Omaha, Nebraska, Forenede Stater, 68124
- Alegant Health Cancer Center at Bergan Mercy Medical Center
-
Omaha, Nebraska, Forenede Stater, 68131-2197
- Creighton University Medical center
-
Omaha, Nebraska, Forenede Stater, 68114
- Methodist Estabrook Cancer Center
-
-
Nevada
-
Las Vegas, Nevada, Forenede Stater, 89102
- University Medical Center of Southern Nevada
-
Las Vegas, Nevada, Forenede Stater, 89106
- CCOP - Nevada Cancer Research Foundation
-
-
New Hampshire
-
Concord, New Hampshire, Forenede Stater, 03301
- New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
-
Exeter, New Hampshire, Forenede Stater, 03833
- Center for Cancer Care at Exeter Hospital
-
Hooksett, New Hampshire, Forenede Stater, 03106
- New Hampshire Oncology - Hematology, PA - Hooksett
-
Laconia, New Hampshire, Forenede Stater, 03246
- Lakes Region General Hospital
-
Manchester, New Hampshire, Forenede Stater, 03103
- Elliot Regional Cancer Center at Elliot Hospital
-
-
New Jersey
-
Hamilton, New Jersey, Forenede Stater, 08690
- Cancer Institute of New Jersey at Hamilton
-
Morristown, New Jersey, Forenede Stater, 07962
- Carol G. Simon Cancer Center at Morristown Memorial Hospital
-
New Brunswick, New Jersey, Forenede Stater, 08903
- Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School
-
Ridgewood, New Jersey, Forenede Stater, 07450
- Valley Hospital - Ridgewood
-
Somerville, New Jersey, Forenede Stater, 08876
- Somerset Medical Center
-
Summit, New Jersey, Forenede Stater, 07902
- Overlook Hospital
-
Voorhees, New Jersey, Forenede Stater, 08043
- Cancer Institute of New Jersey at Cooper - Voorhees
-
-
New York
-
Brooklyn, New York, Forenede Stater, 11209
- Veterans Affairs Medical Center - Brooklyn
-
Buffalo, New York, Forenede Stater, 14263-0001
- Roswell Park Cancer Institute
-
East Syracuse, New York, Forenede Stater, 13057
- CCOP - Hematology-Oncology Associates of Central New York
-
Glens Falls, New York, Forenede Stater, 12801
- Adirondack Cancer Care - Glens Falls
-
New York, New York, Forenede Stater, 10016
- NYU Cancer Institute at New York University Medical Center
-
New York, New York, Forenede Stater, 10025
- St. Luke's - Roosevelt Hospital Center - St.Luke's Division
-
New York, New York, Forenede Stater, 10003-3803
- Beth Israel Medical Center - Petrie Division
-
Oceanside, New York, Forenede Stater, 11572
- South Nassau Communities Hospital
-
Rochester, New York, Forenede Stater, 14642
- James P. Wilmot Cancer Center at University of Rochester Medical Center
-
Rochester, New York, Forenede Stater, 14620
- Highland Hospital of Rochester
-
Rochester, New York, Forenede Stater, 14611
- Unity Health System Cancer Care
-
Syracuse, New York, Forenede Stater, 13210
- Veterans Affairs Medical Center - Syracuse
-
Syracuse, New York, Forenede Stater, 13210
- SUNY Upstate Medical University Hospital
-
Utica, New York, Forenede Stater, 13502
- Faxton Regional Cancer Center
-
-
North Carolina
-
Asheboro, North Carolina, Forenede Stater, 27203-5400
- Randolph Hospital
-
Eden, North Carolina, Forenede Stater, 27288
- John Smith, Jr. - Dalton McMichael Cancer Center at Morehead Memorial Hospital
-
Goldsboro, North Carolina, Forenede Stater, 27534
- Wayne Memorial Hospital, Incorporated
-
Greensboro, North Carolina, Forenede Stater, 27403-1198
- Moses Cone Regional Cancer Center at Wesley Long Community Hospital
-
Greenville, North Carolina, Forenede Stater, 27834
- Leo W. Jenkins Cancer Center at ECU Medical School
-
Reidsville, North Carolina, Forenede Stater, 27320
- Annie Penn Cancer Center
-
Rutherfordton, North Carolina, Forenede Stater, 28139
- Rutherford Hospital
-
Winston-Salem, North Carolina, Forenede Stater, 27157-1096
- Wake Forest University Comprehensive Cancer Center
-
-
North Dakota
-
Fargo, North Dakota, Forenede Stater, 58122
- CCOP - MeritCare Hospital
-
Fargo, North Dakota, Forenede Stater, 58122
- MeritCare Broadway
-
Minot, North Dakota, Forenede Stater, 58701
- Trinity Cancercare Center
-
-
Ohio
-
Akron, Ohio, Forenede Stater, 44307
- McDowell Cancer Center at Akron General Medical Center
-
Bellefontaine, Ohio, Forenede Stater, 43311
- Mary Rutan Hospital
-
Bowling Green, Ohio, Forenede Stater, 43402
- Wood County Oncology Center
-
Canton, Ohio, Forenede Stater, 44710-1799
- Aultman Cancer Center at Aultman Hospital
-
Canton, Ohio, Forenede Stater, 44708
- Mercy Cancer Center at Mercy Medical Center
-
Chillicothe, Ohio, Forenede Stater, 45601
- Adena Regional Medical Center
-
Cincinnati, Ohio, Forenede Stater, 45267
- Charles M. Barrett Cancer Center at University Hospital
-
Clyde, Ohio, Forenede Stater, 43410
- North Coast Cancer Care - Clyde
-
Columbus, Ohio, Forenede Stater, 43214-3998
- Riverside Methodist Hospital Cancer Care
-
Columbus, Ohio, Forenede Stater, 43222
- Mount Carmel Health - West Hospital
-
Columbus, Ohio, Forenede Stater, 43210-1240
- Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center
-
Columbus, Ohio, Forenede Stater, 43215
- CCOP - Columbus
-
Columbus, Ohio, Forenede Stater, 43215
- Grant Medical Center Cancer Care
-
Columbus, Ohio, Forenede Stater, 43228
- Doctors Hospital at Ohio Health
-
Dayton, Ohio, Forenede Stater, 45405
- Grandview Hospital
-
Dayton, Ohio, Forenede Stater, 45406
- Good Samaritan Hospital
-
Dayton, Ohio, Forenede Stater, 45409
- David L. Rike Cancer Center at Miami Valley Hospital
-
Dayton, Ohio, Forenede Stater, 45415
- Samaritan North Cancer Care Center
-
Dayton, Ohio, Forenede Stater, 45429
- CCOP - Dayton
-
Delaware, Ohio, Forenede Stater, 43015
- Grady Memorial Hospital
-
Elyria, Ohio, Forenede Stater, 44035
- Hematology Oncology Center
-
Findlay, Ohio, Forenede Stater, 45840
- Blanchard Valley Medical Associates
-
Franklin, Ohio, Forenede Stater, 45005-1066
- Middletown Regional Hospital
-
Greenville, Ohio, Forenede Stater, 45331
- Wayne Hospital
-
Kettering, Ohio, Forenede Stater, 45429
- Charles F. Kettering Memorial Hospital
-
Lancaster, Ohio, Forenede Stater, 43130
- Fairfield Medical Center
-
Lima, Ohio, Forenede Stater, 45804
- Lima Memorial Hospital
-
Lima, Ohio, Forenede Stater, 45801
- St. Rita's Medical Center
-
Marietta, Ohio, Forenede Stater, 45750
- Strecker Cancer Center at Marietta Memorial Hospital
-
Maumee, Ohio, Forenede Stater, 43537
- St. Luke's Hospital
-
Maumee, Ohio, Forenede Stater, 43537-1839
- Northwest Ohio Oncology Center
-
Newark, Ohio, Forenede Stater, 43055
- Licking Memorial Cancer Care Program at Licking Memorial Hospital
-
Oregon, Ohio, Forenede Stater, 43616
- St. Charles Mercy Hospital
-
Oregon, Ohio, Forenede Stater, 43616
- Toledo Clinic - Oregon
-
Sandusky, Ohio, Forenede Stater, 44870
- North Coast Cancer Care, Incorporated
-
Springfield, Ohio, Forenede Stater, 45505
- Community Hospital of Springfield and Clark County
-
Springfield, Ohio, Forenede Stater, 45504
- Mercy Medical Center
-
Sylvania, Ohio, Forenede Stater, 43560
- Flower Hospital Cancer Center
-
Tiffin, Ohio, Forenede Stater, 44883
- Mercy Hospital of Tiffin
-
Toledo, Ohio, Forenede Stater, 43608
- St. Vincent Mercy Medical Center
-
Toledo, Ohio, Forenede Stater, 43606
- Toledo Hospital
-
Toledo, Ohio, Forenede Stater, 43614
- Medical University of Ohio Cancer Center
-
Toledo, Ohio, Forenede Stater, 43617
- CCOP - Toledo Community Hospital
-
Toledo, Ohio, Forenede Stater, 43623
- Toledo Clinic, Incorporated - Main Clinic
-
Toledo, Ohio, Forenede Stater, 43623
- St. Anne Mercy Hospital
-
Troy, Ohio, Forenede Stater, 45373-1300
- UVMC Cancer Care Center at Upper Valley Medical Center
-
Wauseon, Ohio, Forenede Stater, 43567
- Fulton County Health Center
-
Westerville, Ohio, Forenede Stater, 43081
- Mount Carmel St. Ann's Cancer Center
-
Wilmington, Ohio, Forenede Stater, 45177
- Clinton Memorial Hospital
-
Wright-Patterson Air Force Base, Ohio, Forenede Stater, 45433-5529
- United States Air Force Medical Center - Wright-Patterson
-
Xenia, Ohio, Forenede Stater, 45385
- Ruth G. McMillan Cancer Center at Greene Memorial Hospital
-
Zanesville, Ohio, Forenede Stater, 43701
- Genesis - Good Samaritan Hospital
-
-
Oregon
-
Coos Bay, Oregon, Forenede Stater, 97420
- Bay Area Hospital
-
Portland, Oregon, Forenede Stater, 97232
- Kaiser Permanente Health Care - Portland
-
-
Pennsylvania
-
Allentown, Pennsylvania, Forenede Stater, 18105
- Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
-
Bethlehem, Pennsylvania, Forenede Stater, 18015
- St. Luke's Cancer Network at St. Luke's Hospital
-
Bryn Mawr, Pennsylvania, Forenede Stater, 19010
- Bryn Mawr Hospital
-
Danville, Pennsylvania, Forenede Stater, 17822-0001
- Geisinger Cancer Institute at Geisinger Health
-
Darby, Pennsylvania, Forenede Stater, 19023
- Mercy Fitzgerald Hospital
-
Hazleton, Pennsylvania, Forenede Stater, 18201
- Geisinger Hazleton Cancer Center
-
Hershey, Pennsylvania, Forenede Stater, 17033-0850
- Penn State Cancer Institute at Milton S. Hershey Medical Center
-
Lewistown, Pennsylvania, Forenede Stater, 17044
- Lewistown Hospital
-
Media, Pennsylvania, Forenede Stater, 19063
- Riddle Memorial Hospital Cancer Center
-
Paoli, Pennsylvania, Forenede Stater, 19301-1792
- Cancer Center of Paoli Memorial Hospital
-
Philadelphia, Pennsylvania, Forenede Stater, 19111-2497
- Fox Chase Cancer Center - Philadelphia
-
Philadelphia, Pennsylvania, Forenede Stater, 19104-4283
- Abramson Cancer Center of the University of Pennsylvania
-
Philadelphia, Pennsylvania, Forenede Stater, 19141
- Albert Einstein Cancer Center
-
Philadelphia, Pennsylvania, Forenede Stater, 19107-5541
- Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
-
Philadelphia, Pennsylvania, Forenede Stater, 19107
- Joan Karnell Cancer Center at Pennsylvania Hospital
-
Pittsburgh, Pennsylvania, Forenede Stater, 15232
- UPMC Cancer Centers
-
Pottstown, Pennsylvania, Forenede Stater, 19464
- Pottstown Memorial Regional Cancer Center
-
Sayre, Pennsylvania, Forenede Stater, 18840
- Guthrie Cancer Center at Guthrie Clinic Sayre
-
State College, Pennsylvania, Forenede Stater, 16803
- Mount Nittany Medical Center
-
State College, Pennsylvania, Forenede Stater, 16801
- Geisinger Medical Group - Scenery Park
-
West Grove, Pennsylvania, Forenede Stater, 19390-9499
- Jennersville Regional Hospital
-
Wilkes-Barre, Pennsylvania, Forenede Stater, 18711
- Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center
-
Williamsport, Pennsylvania, Forenede Stater, 17701
- Susquehanna Cancer Center at Divine Providence Hospital
-
Wynnewood, Pennsylvania, Forenede Stater, 19096
- Lankenau Cancer Center at Lankenau Hospital
-
Wynnewood, Pennsylvania, Forenede Stater, 19096
- CCOP - Main Line Health
-
York, Pennsylvania, Forenede Stater, 17405
- York Cancer Center at Apple Hill Medical Center
-
-
Rhode Island
-
Providence, Rhode Island, Forenede Stater, 02906
- Miriam Hospital
-
Providence, Rhode Island, Forenede Stater, 02903
- Rhode Island Hospital Comprehensive Cancer Center
-
-
South Carolina
-
Anderson, South Carolina, Forenede Stater, 29621
- AnMed Cancer Center
-
Charleston, South Carolina, Forenede Stater, 29401
- Roper St. Francis Cancer Center at Roper Hospital
-
Greenville, South Carolina, Forenede Stater, 29615
- CCOP - Greenville
-
Spartanburg, South Carolina, Forenede Stater, 29303
- CCOP - Upstate Carolina
-
Spartanburg, South Carolina, Forenede Stater, 29303
- Gibbs Regional Cancer Center at Spartanburg Regional Medical Center
-
-
South Dakota
-
Sioux Falls, South Dakota, Forenede Stater, 57105
- Avera Cancer Institute
-
Sioux Falls, South Dakota, Forenede Stater, 57105
- Medical X-Ray Center, PC
-
Sioux Falls, South Dakota, Forenede Stater, 57117-5039
- Sanford Cancer Center at Sanford USD Medical Center
-
-
Tennessee
-
Kingsport, Tennessee, Forenede Stater, 37662
- Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center
-
Knoxville, Tennessee, Forenede Stater, 37920-6999
- U.T. Medical Center Cancer Institute
-
Memphis, Tennessee, Forenede Stater, 38104
- Veterans Affairs Medical Center - Memphis
-
Memphis, Tennessee, Forenede Stater, 38104
- University of Tennessee Cancer Institute - Memphis
-
Nashville, Tennessee, Forenede Stater, 37232-6838
- Vanderbilt-Ingram Cancer Center
-
-
Texas
-
Dallas, Texas, Forenede Stater, 75390
- Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas
-
Fort Sam Houston, Texas, Forenede Stater, 78234-6200
- Brooke Army Medical Center
-
Lackland Air Force Base, Texas, Forenede Stater, 78236
- Wilford Hall Medical Center
-
Lubbock, Texas, Forenede Stater, 79410-1894
- Joe Arrington Cancer Research and Treatment Center
-
San Antonio, Texas, Forenede Stater, 78229
- Cancer Therapy and Research Center
-
San Antonio, Texas, Forenede Stater, 78209
- Veterans Affairs Medical Center - San Antonio (Murphy)
-
San Antonio, Texas, Forenede Stater, 78229-3900
- University of Texas Health Science Center at San Antonio
-
San Antonio, Texas, Forenede Stater, 78229
- University Hospital - San Antonio
-
-
Utah
-
Salt Lake City, Utah, Forenede Stater, 84112
- Huntsman Cancer Institute at University of Utah
-
-
Virginia
-
Charlottesville, Virginia, Forenede Stater, 22908
- University of Virginia Cancer Center
-
Danville, Virginia, Forenede Stater, 24541
- Danville Regional Medical Center
-
Fredericksburg, Virginia, Forenede Stater, 22401
- Fredericksburg Oncology, Incorporated
-
Hampton, Virginia, Forenede Stater, 23666
- Virginia Oncology Associates - Hampton
-
Norton, Virginia, Forenede Stater, 24273
- Southwest Virginia Regional Cancer Center at Wellmonth Health
-
-
Washington
-
Auburn, Washington, Forenede Stater, 98002
- Auburn Regional Center for Cancer Care
-
Bellingham, Washington, Forenede Stater, 98225
- St. Joseph Cancer Center
-
Bremerton, Washington, Forenede Stater, 98310
- Olympic Hematology and Oncology
-
Centralia, Washington, Forenede Stater, 98531-9027
- Providence Centralia Hospital
-
Federal Way, Washington, Forenede Stater, 98003
- St. Francis Hospital
-
Kennewick, Washington, Forenede Stater, 99336
- Columbia Basin Hematology
-
Olympia, Washington, Forenede Stater, 98506-5166
- Providence St. Peter Hospital Regional Cancer Center
-
Puyallup, Washington, Forenede Stater, 98372
- Good Samaritan Cancer Center
-
Seattle, Washington, Forenede Stater, 98104
- Harborview Medical Center
-
Seattle, Washington, Forenede Stater, 98104
- Fred Hutchinson Cancer Research Center
-
Seattle, Washington, Forenede Stater, 98104
- Minor and James Medical, PLLC
-
Seattle, Washington, Forenede Stater, 98112
- Group Health Central Hospital
-
Seattle, Washington, Forenede Stater, 98122-4307
- Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
-
Seattle, Washington, Forenede Stater, 98122
- Polyclinic First Hill
-
Seattle, Washington, Forenede Stater, 98195-6043
- University Cancer Center at University of Washington Medical Center
-
Spokane, Washington, Forenede Stater, 99202
- Cancer Care Northwest - Spokane South
-
Tacoma, Washington, Forenede Stater, 98405-3004
- Franciscan Cancer Center at St. Joseph Medical Center
-
Tacoma, Washington, Forenede Stater, 98405
- Allenmore Hospital
-
Tacoma, Washington, Forenede Stater, 98405
- CCOP - Northwest
-
Tacoma, Washington, Forenede Stater, 98405
- MultiCare Regional Cancer Center at Tacoma General Hospital
-
Tacoma, Washington, Forenede Stater, 98499
- St. Clare Hospital
-
Tacoma, Washington, Forenede Stater, 98431
- Madigan Army Medical Center - Tacoma
-
-
West Virginia
-
Wheeling, West Virginia, Forenede Stater, 26003
- Schiffler Cancer Center at Wheeling Hospital
-
-
Wisconsin
-
Appleton, Wisconsin, Forenede Stater, 54911-3496
- Fox Valley Hematology and Oncology - East Grant Street
-
Chippewa Falls, Wisconsin, Forenede Stater, 54729
- Marshfield Clinic - Chippewa Center
-
Eau Claire, Wisconsin, Forenede Stater, 54701
- Center for Cancer Treatment & Prevention at Sacred Heart Hospital
-
Eau Claire, Wisconsin, Forenede Stater, 54701
- Marshfield Clinic Cancer Care at Regional Cancer Center
-
Green Bay, Wisconsin, Forenede Stater, 54307-3508
- St. Vincent Hospital Regional Cancer Center
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Green Bay, Wisconsin, Forenede Stater, 54301-3526
- Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center
-
Green Bay, Wisconsin, Forenede Stater, 54303
- Green Bay Oncology, Limited at St. Mary's Hospital
-
Green Bay, Wisconsin, Forenede Stater, 54303
- St. Mary's Hospital Medical Center - Green Bay
-
La Crosse, Wisconsin, Forenede Stater, 54601
- Gundersen Lutheran Center for Cancer and Blood
-
La Crosse, Wisconsin, Forenede Stater, 54601
- Franciscan Skemp Healthcare - La Crosse Campus
-
Madison, Wisconsin, Forenede Stater, 53792-6164
- University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
-
Marinette, Wisconsin, Forenede Stater, 54143
- Bay Area Cancer Care Center at Bay Area Medical Center
-
Marshfield, Wisconsin, Forenede Stater, 54449
- Saint Joseph's Hospital
-
Marshfield, Wisconsin, Forenede Stater, 54449
- Marshfield Clinic - Marshfield Center
-
Minocqua, Wisconsin, Forenede Stater, 54548
- Marshfield Clinic - Lakeland Center
-
Oconomowoc, Wisconsin, Forenede Stater, 53066
- Regional Cancer Center at Oconomowoc Memorial Hospital
-
Oconto Falls, Wisconsin, Forenede Stater, 54154
- Green Bay Oncology, Limited - Oconto Falls
-
Racine, Wisconsin, Forenede Stater, 53405
- All Saints Cancer Center at Wheaton Franciscan Healthcare
-
Rhinelander, Wisconsin, Forenede Stater, 54501
- Ministry Medical Group at Saint Mary's Hospital
-
Rice Lake, Wisconsin, Forenede Stater, 54868
- Marshfield Clinic - Indianhead Center
-
Stevens Point, Wisconsin, Forenede Stater, 54481
- Marshfield Clinic at Saint Michael's Hospital
-
Stevens Point, Wisconsin, Forenede Stater, 54481
- Saint Michael's Hospital Cancer Center
-
Sturgeon Bay, Wisconsin, Forenede Stater, 54235
- Green Bay Oncology, Limited - Sturgeon Bay
-
Waukesha, Wisconsin, Forenede Stater, 53188
- Waukesha Memorial Hospital Regional Cancer Center
-
Wausau, Wisconsin, Forenede Stater, 54401
- Marshfield Clinic - Wausau Center
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Weston, Wisconsin, Forenede Stater, 54476
- Diagnostic and Treatment Center
-
Weston, Wisconsin, Forenede Stater, 54476
- Marshfield Clinic - Weston Center
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Wisconsin Rapids, Wisconsin, Forenede Stater, 54494
- Marshfield Clinic - Wisconsin Rapids Center
-
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Wyoming
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Sheridan, Wyoming, Forenede Stater, 82801
- Welch Cancer Center at Sheridan Memorial Hospital
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Deltagelseskriterier
Berettigelseskriterier
Aldre berettiget til at studere
Tager imod sunde frivillige
Beskrivelse
INDKØRINGSPERIODE:
Inklusionskriterier:
Histologisk bekræftet, fuldstændigt resekeret stadium IA (pT1, N0) eller IB (pT2, N0) ikke-små lungekræft (undtagen carcinoid)*
- Afslutning af behandling for fase I lungekræft inden for de seneste 6 til 36 måneder og i øjeblikket sygdomsfri
- Mindst én mediastinal lymfeknude udtaget ved resektion BEMÆRK: *Southwest Oncology Group (SWOG) og kræft- og leukæmigruppe B (CALGB) patienter skal være T1, N0; CALGB-patienter kan være T2, N0, forudsat at sygdommen var fuldstændigt resekteret før 1. juni 2001, og deltagelse i CALGB 9633 blev nægtet, hvis det blev tilbudt
- 18 år og derover
- Eastern Cooperative Oncology Group præstationsstatus 0-1
- Bilirubin ikke større end øvre normalgrænse (ULN)
- Serumglutamin-oxaloeddikesyretransaminase (SGOT) eller serumglutaminsyre-pyrodruesyretransaminase (SGPT) ikke højere end ULN
- Forudgående mineral-, urte-, fytokemiske eller vitamintilskud tilladt
- Samtidig ikke-selenholdig mineral-, urte-, fytokemisk eller vitamintilskud tilladt, hvis tidsplan og tilskud forud for undersøgelsen forbliver uændret
Ekskluderingskriterier:
- Bevis på ny eller tilbagevendende lungekræft på røntgen af thorax inden for de seneste 8 uger
- Synkrone lunge- eller ikke-lungelæsioner eller metastaser, selv om de er resektable
- Anamnese med mere end én primær lungekræft på ethvert tidspunkt
- Samtidig eller anden tidligere cancer inden for de seneste 5 år undtagen lokaliseret ikke-melanom hudkræft
- Forudgående eller samtidig kemoterapi ved tilbagevendende lungekræft
- Forudgående eller samtidig strålebehandling ved tilbagevendende lungekræft
- Samtidig operation
- Samtidige tilskud, der indeholder mere end 50 mikrogram selen
STUDIEFASE:
- Fri for sygdom
- Indtog mindst 75 % af tabletterne i løbet af 4 ugers indkøringsperiode
Studieplan
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Forebyggelse
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Tredobbelt
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
|---|---|
|
Placebo komparator: Arm I
Deltagerne får en oral gærplacebo som i arm II.
|
Gives oralt
|
|
Eksperimentel: Arm II
Deltagerne modtager oral selengær dagligt i 6 måneder.
Behandlingen gentages hver 6. måned i 8 forløb i i alt 4 år i fravær af uacceptabel toksicitet.
|
Gives oralt
Andre navne:
|
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Incidensrate af anden primær lungetumor
Tidsramme: Vurderes årligt i 10 år efter randomisering
|
Hyppigheden af anden primær lungetumor blev defineret som antallet af nye sekundære primære lungetumorer pr. 100 risikobefolkning i løbet af et år.
|
Vurderes årligt i 10 år efter randomisering
|
Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
5-års progressionsfri overlevelsesrate
Tidsramme: Vurderes årligt i 5 år efter randomisering
|
Progressionsfri overlevelse (PFS) blev defineret som tiden fra randomisering til anden primær lungekræft eller recidiv. Sager uden begivenheder er blevet censureret på tidspunktet for sidst kendte i live. Kaplan-Meier metode blev brugt til at estimere 5-års PFS rate. Nøjagtig bestemmelse af, om en kræftforekomst er recidiv, eller om det er en anden primær er kritisk. Alle mistænkelige læsioner identificeret klinisk og/eller radiografisk blev verificeret histologisk. Patienter med mindst én af følgende anses for at have anden primær lungekræft.
|
Vurderes årligt i 5 år efter randomisering
|
|
5-års samlet overlevelsesrate
Tidsramme: Vurderes årligt i 5 år efter randomisering
|
Samlet overlevelse (OS) blev defineret som tiden fra randomisering til død på grund af enhver årsag.
Sager uden død var blevet censureret på tidspunktet for sidst kendte i live.
Kaplan-Meier metode blev brugt til at estimere 5-års OS rate.
|
Vurderes årligt i 5 år efter randomisering
|
Samarbejdspartnere og efterforskere
Sponsor
Samarbejdspartnere
Efterforskere
- Studiestol: Daniel D. Karp, MD, M.D. Anderson Cancer Center
- Studiestol: Michael R. Johnston, MD, FRCSC, Nova Scotia Cancer Centre
- Studiestol: Gerald H. Clamon, MD, Holden Comprehensive Cancer Center
- Studiestol: Gord Okawara, MD, Margaret and Charles Juravinski Cancer Centre
- Studiestol: Randolph S. Marks, MD, Mayo Clinic
- Studiestol: Omer Kucuk, MD, Barbara Ann Karmanos Cancer Institute
Datoer for undersøgelser
Studer store datoer
Studiestart (Faktiske)
Primær færdiggørelse (Faktiske)
Studieafslutning (Faktiske)
Datoer for studieregistrering
Først indsendt
Først indsendt, der opfyldte QC-kriterier
Først opslået (Anslået)
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
Sidst verificeret
Mere information
Begreber relateret til denne undersøgelse
Nøgleord
Yderligere relevante MeSH-vilkår
- Luftvejssygdomme
- Neoplasmer
- Lungesygdomme
- Neoplasmer efter sted
- Neoplasmer i luftvejene
- Thoracale neoplasmer
- Karcinom, bronkogent
- Bronkiale neoplasmer
- Lungeneoplasmer
- Karcinom, ikke-småcellet lunge
- Lægemidlers fysiologiske virkninger
- Molekylære mekanismer for farmakologisk virkning
- Beskyttelsesagenter
- Sporelementer
- Mikronæringsstoffer
- Antioxidanter
- Selen
Andre undersøgelses-id-numre
- E5597 (Anden identifikator: ECOG-ACRIN Cancer Research Group)
- U10CA023318 (U.S. NIH-bevilling/kontrakt)
- CDR0000068402 (Registry Identifier: CTRP (Clinical Trial Reporting Program))
Plan for individuelle deltagerdata (IPD)
Planlægger du at dele individuelle deltagerdata (IPD)?
IPD-planbeskrivelse
Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .
Kliniske forsøg med Lungekræft
-
Seoul National University HospitalAfsluttet
-
Seoul National University HospitalAfsluttet
-
Chinese Chronic Respiratory Disease Research NetworkRekruttering
-
Mansoura UniversityAfsluttetOne Lung VentilationEgypten
-
Dokuz Eylul UniversityAfsluttetOne Lung VentilationKalkun
-
Yonsei UniversityAfsluttetOne Lung VentilationKorea, Republikken
-
Sichuan UniversityWest China HospitalMidlertidigt ikke tilgængeligOne Lung Ventilation
-
Luca BrazziA.O.U. Città della Salute e della Scienza - Molinette HospitalIkke rekrutterer endnuIntubationskomplikation | One Lung Ventilation
-
Ankara Ataturk Sanatorium Training and Research...Ikke rekrutterer endnuOne-lung Ventilation (OLV)Tyrkiet (Türkiye)
-
Joseph D. TobiasAfsluttetOne-lung Ventilation (OLV)Forenede Stater
Kliniske forsøg med placebo
-
SamA Pharmaceutical Co., LtdUkendtAkut bronkitis | Akut øvre luftvejsinfektionKorea, Republikken
-
National Institute on Drug Abuse (NIDA)AfsluttetBrug af cannabisForenede Stater
-
AkesoIkke rekrutterer endnuAtopisk dermatitisKina
-
AstraZenecaParexel; Spandauer Damm 130; 14050; Berlin, GermanyAfsluttetMandlige forsøgspersoner med type II-diabetes (T2DM)Tyskland
-
CellmedisMedical Network Sp. z o.o.Ikke rekrutterer endnu
-
Texas A&M UniversityNutraboltAfsluttetGlukose og insulinrespons
-
Heptares Therapeutics LimitedAfsluttetFarmakokinetik | SikkerhedsproblemerDet Forenede Kongerige
-
Regado Biosciences, Inc.AfsluttetSund frivilligForenede Stater
-
LifeMine TherapeuticsRekruttering