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Pexelizumab i forbindelse med angioplastik ved akut myokardieinfarkt (APEX-AMI)

17. november 2023 opdateret af: Procter and Gamble

APEX-AMI - Pexelizumab i forbindelse med angioplastik

I forbindelse med reperfusionsterapi i et akut myokardieinfarkt ved hjælp af primær perkutan intervention (PCI), kan kroppens eget inflammatoriske system, der involverer komplementkaskaden, være skadeligt. Denne undersøgelse vil teste sikkerheden og effektiviteten af ​​en ny komplementhæmmer, pexelizumab, til at reducere dødeligheden efter 30 dage.

Studieoversigt

Status

Afsluttet

Betingelser

Intervention / Behandling

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

5745

Fase

  • Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

  • Australien
    • Australian Capital Territory
      • Garran, Australian Capital Territory, Australien, 2605
        • Canberra Hospital
    • New South Wales
      • Concord, New South Wales, Australien, 2137
        • Concord Hospital
      • Gosford, New South Wales, Australien, 2250
        • Gosford Hospital
      • Kogarah, New South Wales, Australien, 2217
        • St. George Hospital
      • Liverpool, New South Wales, Australien, 2170
        • Liverpool Hospital
      • Randwick, New South Wales, Australien, 2031
        • Prince of Wales Hospital
      • St. Leonards, New South Wales, Australien, 2065
        • Royal North Shore Hospital
    • Queensland
      • Chermside, Queensland, Australien, 4032
        • Prince Charles Hospital
      • Douglas, Queensland, Australien, 4814
        • Townsville Hospital
      • Wooloong Abba, Queensland, Australien, 4102
        • Princess Alexandra Hospital
    • South Australia
      • Adelaide, South Australia, Australien, 5000
        • Royal Adelaide Hospital
      • Bedford Park, South Australia, Australien, 5042
        • Flinders Medical Centre
      • Woodville South, South Australia, Australien, 5011
        • The Queen Elizabeth Hospital
    • Victoria
      • Box Hill, Victoria, Australien, 3128
        • Box Hill Hospital
      • Box Hill, Victoria, Australien, 3084
        • Austin Hospital
      • Clayton, Victoria, Australien, 3162
        • Monash Medical Centre
      • Parkville, Victoria, Australien, 3050
        • Royal Melbourne Hospital
      • Richmond, Victoria, Australien, 3121
        • Victorian Heart Clinic
    • Western Australia
      • Fremantle, Western Australia, Australien, 6160
        • Fremantle Hospital
      • Nedlands, Western Australia, Australien, 6009
        • Sir Charles Gairdner Hospital
      • Perth, Western Australia, Australien, 6000
        • Royal Perth Hospital
  • Belgien
      • Antwerpen, Belgien, 2020
        • Az Middelheim
      • Liege, Belgien, 4000
        • CHR de la Citadelle
    • Brabant
      • Leuven, Brabant, Belgien, 3000
        • U.Z. Gasthuisberg
    • Limburg
      • Genk, Limburg, Belgien, 3600
        • ZOL Campus Sint-Jan
    • Vlaanderen
      • Roeselare, Vlaanderen, Belgien, 8800
        • Helig Hartziekenhuis
  • Canada
    • Alberta
      • Calgary, Alberta, Canada, T2N 2W8
        • Foothills Medical Centre
      • Edmonton, Alberta, Canada, T6G 2B7
        • University of Alberta Hospital
    • British Columbia
      • Vancouver, British Columbia, Canada, V6Z 1Y6
        • St. Paul's Hospital
      • Vancouver, British Columbia, Canada, V5Z 1L8
        • Vancouver General Hospital
      • Victoria, British Columbia, Canada, V8R 4R2
        • Royal Jubilee Hospital
    • New Brunswick
      • Saint John, New Brunswick, Canada, E2L 4L2
        • Saint John Regional Hospital - New Brunswick Heart Centre
    • Newfoundland and Labrador
      • St. John's, Newfoundland and Labrador, Canada, A1B 3E4
        • General Hospital Health Sciences Centre
    • Ontario
      • Hamilton, Ontario, Canada, L8L 2X2
        • Hamilton General Hospital
      • Mississauga, Ontario, Canada, L58 2P7
        • Trillium Health Center
      • Toronto, Ontario, Canada, M4N 3M5
        • Sunnybrook & Women's Health Sciences Centre
    • Quebec
      • Montreal, Quebec, Canada, H4J 1C5
        • Hôpital Sacré-Coeur de Montréal
      • Montreal, Quebec, Canada, H1T 1C8
        • Montreal Heart Institute/Research Centre
      • Montreal, Quebec, Canada, H2L 4M1
        • Centre Hospitale de'Universite de Montreal (Pav Notre-Dame)_
      • Sainte-Foy, Quebec, Canada, G1V 4G5
        • Quebec Heart Institute/Laval Hospital
      • Sherbrooke, Quebec, Canada, J1H 5N4
        • Centre Hospitalier Universitaire de Sherbrooke
    • Saskatchewan
      • Regina, Saskatchewan, Canada, S4P 0W5
        • Regina General Hospital
  • Danmark
      • Odense, Danmark, 5000
        • Odense Universitets Hospital
    • Danmark
      • Aalborg, Danmark, Danmark, 9100
        • Aalborg Sygehus
      • Aarhus, Danmark, Danmark, 8200
        • Skejby Sygehus
      • Hellerup, Danmark, Danmark, 2900
        • Amtssygehuset i Gentofte
      • Kobenhavn, Danmark, Danmark, DK-2100
        • Rigshospitalet
  • Forenede Stater
    • Alabama
      • Huntsville, Alabama, Forenede Stater, 35801
        • Huntsville Hospital
    • Arizona
      • Phoenix, Arizona, Forenede Stater, 85054
        • Mayo Clinic Hospital
      • Phoenix, Arizona, Forenede Stater
        • North Phoenix Heart Center
      • Tucson, Arizona, Forenede Stater, 85741
        • Northwest Medical Center
    • Arkansas
      • Fort Smith, Arkansas, Forenede Stater, 72901
        • Sparks Regional Medical Center
      • Little Rock, Arkansas, Forenede Stater, 72211
        • Arkansas State Hospital
    • California
      • Beverly Hills, California, Forenede Stater, 90230
        • Brotman Medical Center
      • Burbank, California, Forenede Stater, 91505
        • Providence Saint Joseph Medical Center
      • Escondido, California, Forenede Stater, 92025
        • Palomar Medical Center
      • Los Angeles, California, Forenede Stater, 90033
        • Los Angeles Community Hospital
      • Modesto, California, Forenede Stater, 48201
        • Memorial Medical Center
      • Sacramento, California, Forenede Stater, 95825
        • Sutter Memorial Hospital
      • San Diego, California, Forenede Stater, 92103-8784
        • University of CA, San Diego Medical
      • Santa Rosa, California, Forenede Stater, 95403
        • Sutter Medical Center of Santa Rosa
      • Valencia, California, Forenede Stater, 91355
        • Providence Holy Cross Medical Center
    • Colorado
      • Denver, Colorado, Forenede Stater, 80262
        • University Of Colorado Hospital
    • Connecticut
      • Bridgeport, Connecticut, Forenede Stater, 06606
        • St. Vincent Medical Center
      • Farmington, Connecticut, Forenede Stater, 06030-2202
        • University of Connecticut Health Center
      • New Haven, Connecticut, Forenede Stater, 06520
        • Yale - New Haven
    • District of Columbia
      • Washington, District of Columbia, Forenede Stater, 20037
        • George Washington University Hospital
    • Florida
      • Atlantis, Florida, Forenede Stater, 33462
        • JFK Medical Center
      • Clearwater, Florida, Forenede Stater, 33756
        • Morton Plant Hospital
      • Fort Lauderdale, Florida, Forenede Stater, 33308
        • North Ridge Medical Center
      • Jacksonville, Florida, Forenede Stater, 32224
        • St. Luke's Hospital
      • Melbourne, Florida, Forenede Stater, 32001
        • Health First Holmes Regional Medical Center
      • Orlando, Florida, Forenede Stater, 32803
        • Florida Heart Hospital
      • Sarasota, Florida, Forenede Stater, 34239
        • Sarasota Memorial Hospital
      • Tampa, Florida, Forenede Stater, 33613
        • University Community Hospital
    • Idaho
      • Boise, Idaho, Forenede Stater, 63704
        • St. Luke's Regional Medical Center
    • Illinois
      • Bannockburn, Illinois, Forenede Stater, 60015
        • Highland Park Hospital
      • Harvey, Illinois, Forenede Stater, 80426
        • Ingalls Hospital
      • Lombard, Illinois, Forenede Stater, 60148
        • Advocate Good Samaritan
      • Lombard, Illinois, Forenede Stater, 60148
        • Elmhurst Hospital
      • Moline, Illinois, Forenede Stater, 61265
        • Trinity Medical Center
      • Peoria, Illinois, Forenede Stater, 61603
        • Saint Francis Medical Center
      • Rock Island, Illinois, Forenede Stater, 61201
        • Trinity Medical Center
    • Indiana
      • Indianapolis, Indiana, Forenede Stater, 46202
        • Methodist Hospital
      • Indianapolis, Indiana, Forenede Stater, 46227
        • Community Hospital South
      • Indianapolis, Indiana, Forenede Stater, 46202
        • VAMC
      • Indianapolis, Indiana, Forenede Stater, 56250
        • The Indiana Heart Hospital
      • Munster, Indiana, Forenede Stater, 46321
        • Munster Community Hospital
    • Iowa
      • Des Moines, Iowa, Forenede Stater, 50314
        • Iowa Heart
    • Kansas
      • Wichita, Kansas, Forenede Stater, 67214
        • Via Christi Reginal Medical Center
    • Kentucky
      • Lexington, Kentucky, Forenede Stater, 40503
        • Central Baptist Hospital
      • Lexington, Kentucky, Forenede Stater, 40536-0200
        • University of Kentucky
      • Louisville, Kentucky, Forenede Stater, 40207
        • Baptist Hospital East
      • Louisville, Kentucky, Forenede Stater, 40202
        • The Jewish Hospital
    • Louisiana
      • Chalmette, Louisiana, Forenede Stater, 70043
        • Lousiana Heart Center
      • Lacombe, Louisiana, Forenede Stater, 70445
        • Lousiana Heart Hospital
      • New Orleans, Louisiana, Forenede Stater, 70112
        • Tulane University Hospital and Clinic
      • New Orleans, Louisiana, Forenede Stater, 70112
        • MCLNO at New Orleans University Campus
    • Maine
      • Bangor, Maine, Forenede Stater, 04401
        • Eastern Maine Medical Center
      • Portland, Maine, Forenede Stater, 04102
        • Maine Medical Center
    • Maryland
      • Towson, Maryland, Forenede Stater, 21204
        • St. Joseph Medical Center
    • Michigan
      • Dearborn, Michigan, Forenede Stater, 48123
        • Oakwood Hospital and Medical Center
      • Detroit, Michigan, Forenede Stater, 48202
        • Henry Ford Hospital
      • Detroit, Michigan, Forenede Stater, 48235
        • Sinai-Grace Hospital
      • Grand Rapids, Michigan, Forenede Stater, 49503
        • Spectrum Health
      • Kalamazoo, Michigan, Forenede Stater, 49048
        • Borgess Medical Center
      • Muskegon, Michigan, Forenede Stater, 49444
        • Mercy General Health Partners
      • Petoskey, Michigan, Forenede Stater, 49770
        • Northern Michigan Hospital
      • Pontiac, Michigan, Forenede Stater, 48341-2982
        • St. Joseph Mercy-Oakland
      • Royal Oak, Michigan, Forenede Stater, 48073
        • William Beaumont Hospital
      • Saginaw, Michigan, Forenede Stater, 48601
        • Covenant Medical Center
      • Saginaw, Michigan, Forenede Stater, 48601
        • Saint Mary Medical Center
      • Southfield, Michigan, Forenede Stater, 48075
        • Providence Hospital
      • Troy, Michigan, Forenede Stater, 48085
        • William Beaumont Hospital
      • Warren, Michigan, Forenede Stater, 48201
        • Harper University Hospital
    • Minnesota
      • Coon Rapids, Minnesota, Forenede Stater, 55433
        • Mercy Hospital
      • Duluth, Minnesota, Forenede Stater, 55805
        • St. Mary's Duluth Clinic Health System
      • Edina, Minnesota, Forenede Stater, 55435
        • Fairview Southdale Hospital
      • Minneapolis, Minnesota, Forenede Stater, 55407
        • Abbott Northwestern Hospital
      • Minneapolis, Minnesota, Forenede Stater, 55422
        • North Memorial Medical Center
      • Rochester, Minnesota, Forenede Stater, 55902
        • Saint Mary Hospital
      • Saint Cloud, Minnesota, Forenede Stater, 56303
        • St. Cloud Hospital
      • Saint Louis Park, Minnesota, Forenede Stater, 55426
        • Methodist Hospital
      • Saint Paul, Minnesota, Forenede Stater, 55102
        • Health East St. Joseph Hospital
    • Missouri
      • Columbia, Missouri, Forenede Stater, 65212
        • University of Missouri Health Sciences Center
      • Saint Louis, Missouri, Forenede Stater, 63110
        • St. Louis University Hospital
      • Saint Louis, Missouri, Forenede Stater, 63122
        • Barnes St. Peters Hospital
      • Springfield, Missouri, Forenede Stater, 65807
        • St. John's Hospital
    • Montana
      • Billings, Montana, Forenede Stater, 59101
        • Deaconess Billings Clinic
    • Nebraska
      • Lincoln, Nebraska, Forenede Stater, 68510
        • St. Elizabeth Medical Center
    • Nevada
      • Las Vegas, Nevada, Forenede Stater, 89109
        • Sunrise Hospital
    • New Jersey
      • Elizabeth, New Jersey, Forenede Stater, 07202
        • Trinitas Hospital
      • Fair Lawn, New Jersey, Forenede Stater, 07410
        • St. Joseph's Regional Medical Center
    • New Mexico
      • Albuquerque, New Mexico, Forenede Stater, 87102
        • New Mexico Heart Institute
    • New York
      • Albany, New York, Forenede Stater, 12211
        • Albany Medical Center
      • Bronx, New York, Forenede Stater, 10467
        • Monteflore Medical Center
      • Brooklyn, New York, Forenede Stater, 11219
        • Maimonides Medical Center
      • Johnson City, New York, Forenede Stater, 13790
        • Wilson Memorial Medical Center
      • Mineola, New York, Forenede Stater, 11504
        • Winthrop University Hospital
      • New York, New York, Forenede Stater, 10016
        • Bellevue Hospital Center
      • New York, New York, Forenede Stater, 10011
        • St. Vincent's Catholic Medical Center
      • Poughkeepsie, New York, Forenede Stater, 12601
        • Vassar Brothers Medical Center
      • Rochester, New York, Forenede Stater, 14621
        • Rochester General Hospital
      • Syracuse, New York, Forenede Stater, 13210
        • SUNY - Upstate Medical University
    • North Carolina
      • Charlotte, North Carolina, Forenede Stater, 28204
        • Presbyterian Hospital
      • Durham, North Carolina, Forenede Stater, 27705
        • Duke University Health Systems
      • Greensboro, North Carolina, Forenede Stater, 27401
        • Moses Cone Hospital/LeBauer Healthcare
      • Greenville, North Carolina, Forenede Stater, 27834
        • Pitt County Memorial Hospital
      • High Point, North Carolina, Forenede Stater, 27262
        • High Point Regional Health System
    • North Dakota
      • Minot, North Dakota, Forenede Stater, 58701
        • Trinity Hospital
    • Ohio
      • Akron, Ohio, Forenede Stater, 44307
        • Akron General Medical Center
      • Cincinnati, Ohio, Forenede Stater, 45242
        • Bethesda North Hospital
      • Cincinnati, Ohio, Forenede Stater, 45220
        • VAMC Cincinnati
      • Cincinnati, Ohio, Forenede Stater, 45267
        • The University Hospital
      • Cleveland, Ohio, Forenede Stater, 44195
        • Cleveland Clinic Foundation
      • Cleveland, Ohio, Forenede Stater, 44103
        • University Hospitals of Cleveland
      • Columbus, Ohio, Forenede Stater, 43214
        • MidWest Cardiology Research Foundation
      • Mansfield, Ohio, Forenede Stater, 44906
        • Med Central Mansfield
      • Zanesville, Ohio, Forenede Stater, 43701
        • Genesis HealthCare System
    • Oklahoma
      • Midwest City, Oklahoma, Forenede Stater, 73110
        • Midwest Regional Medical Center
      • Oklahoma City, Oklahoma, Forenede Stater, 73104
        • University of Oklahoma Health Sciences Center
      • Oklahoma City, Oklahoma, Forenede Stater, 73120
        • Oklahoma Heart Hospital
      • Oklahoma City, Oklahoma, Forenede Stater, 73112
        • INTEGRIS Baptist Medical Center, Inc.
      • Oklahoma City, Oklahoma, Forenede Stater, 73104
        • VA Medical Center
    • Oregon
      • Bend, Oregon, Forenede Stater, 97701
        • St. Charles Medical Center
      • Portland, Oregon, Forenede Stater, 97213
        • Providence Portland Medical Center
    • Pennsylvania
      • Allentown, Pennsylvania, Forenede Stater, 18105
        • LeHigh Valley Hospital
      • Danville, Pennsylvania, Forenede Stater, 17822-2160
        • Geisinger Medical Center
      • Davenport, Pennsylvania, Forenede Stater, 58803
        • Genesis Medical Center
      • Erie, Pennsylvania, Forenede Stater, 16550
        • Hamot Medical Center
      • Hershey, Pennsylvania, Forenede Stater, 17033
        • Penn State Milton S. Hershey Medical Center
      • Lancaster, Pennsylvania, Forenede Stater, 17604
        • Lancaster General Hospital
      • Philadelphia, Pennsylvania, Forenede Stater, 19104
        • Hospital of the University of Pennsylvania
      • Philadelphia, Pennsylvania, Forenede Stater, 19140
        • Temple University Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15212
        • Allegheny General Hospital
      • Pittsburgh, Pennsylvania, Forenede Stater, 15240
        • VA Pittsburgh Healthcare System
      • Pittsburgh, Pennsylvania, Forenede Stater, 15025
        • Jefferson Regional Medical Center
      • Pittsburgh, Pennsylvania, Forenede Stater, 15215
        • Western Pennsylvania Hospital
      • West Chester, Pennsylvania, Forenede Stater, 19380
        • The Chester County Hospital
      • York, Pennsylvania, Forenede Stater, 17405
        • York Hospital
    • Rhode Island
      • Providence, Rhode Island, Forenede Stater, 02903
        • Rhode Island Hospital
    • South Carolina
      • Columbia, South Carolina, Forenede Stater, 29203
        • Palmetto Richland Memorial Hospital
      • Columbia, South Carolina, Forenede Stater, 29204
        • Sisters of Charity Providence Hospitals
    • South Dakota
      • Rapid City, South Dakota, Forenede Stater, 57719
        • Rapid City Regional Hospital
      • Sioux Falls, South Dakota, Forenede Stater, 57108
        • Heart Hospital of South Dakota
    • Tennessee
      • Jackson, Tennessee, Forenede Stater, 38301
        • Jackson-Madison County General Hospital
      • Kingsport, Tennessee, Forenede Stater, 37660
        • Wellmont Holston Valley Medical Center
      • Knoxville, Tennessee, Forenede Stater, 37920
        • Baptist Hospital of East Tennessee
      • Knoxville, Tennessee, Forenede Stater, 37916
        • Fort Sanders Rgional Medical Center
      • Nashville, Tennessee, Forenede Stater, 37203
        • Centennial Medical Center
      • Oak Ridge, Tennessee, Forenede Stater, 37830
        • Methodist Medical Center
    • Texas
      • Amarillo, Texas, Forenede Stater, 79106
        • Northwest Texas Healthcare System
      • Austin, Texas, Forenede Stater, 78705
        • Seton Medical Center
      • Dallas, Texas, Forenede Stater, 75230
        • Medical City Dallas
      • Dallas, Texas, Forenede Stater, 75390
        • Parkland Health & Hospital System
      • Dallas, Texas, Forenede Stater, 57231
        • Presbyterian Hospital of Dallas
      • Dallas, Texas, Forenede Stater, 75390
        • Dallas Medical Center
      • Fort Sam Houston, Texas, Forenede Stater, 78234
        • Brooke Army Medical Center
      • Houston, Texas, Forenede Stater, 77030
        • Michael E. DeBakey VA Medical Center
      • Houston, Texas, Forenede Stater, 77030
        • Memorial Hermann Hospital
      • Houston, Texas, Forenede Stater, 77030
        • Ben Taub General Hospital
      • Houston, Texas, Forenede Stater, 77090
        • Houston Northwest Medical Center
      • Lubbock, Texas, Forenede Stater, 79410
        • Covenant Medical Center
      • San Antonio, Texas, Forenede Stater, 78217
        • Northeast Baptist Hospital
      • San Antonio, Texas, Forenede Stater, 78258
        • South Texas Veterans Health Care System Audie L. Murphy Division
      • Temple, Texas, Forenede Stater, 76508
        • Scott & White Memorial Hospital
      • Tyler, Texas, Forenede Stater, 75701
        • East Texas Medical Center
      • Tyler, Texas, Forenede Stater, 75701
        • Trinity Mother Frances Hospital
      • Victoria, Texas, Forenede Stater, 77901
        • Citizens Medical Center
      • Victoria, Texas, Forenede Stater, 77901
        • Detar Hospital
    • Utah
      • Murray, Utah, Forenede Stater, 84107
        • Cottonwood Hospital
    • Virginia
      • Alexandria, Virginia, Forenede Stater, 22306
        • Inova Alexandria Hospital
      • Charlottesville, Virginia, Forenede Stater, 22908
        • Universitiy of Virginia Health Science Center
      • Harrisonburg, Virginia, Forenede Stater, 22801
        • Rockingham Memorial Hospital
      • Lynchburg, Virginia, Forenede Stater, 24501
        • Lynchburg General Hospital
      • Richmond, Virginia, Forenede Stater
        • Herrico Doctors' Hospital - Forest
      • Virginia Beach, Virginia, Forenede Stater, 23454
        • Sentara Virginia Beach General Hospital
      • Winchester, Virginia, Forenede Stater, 22601
        • Winchester Medical Center
    • Washington
      • Bellevue, Washington, Forenede Stater, 98004
        • Overtake Hospital Medical Center
      • Mount Vernon, Washington, Forenede Stater, 98274
        • Skagit Valley Hospital
      • Seattle, Washington, Forenede Stater, 98104
        • Harborview Medical Center
      • Tacoma, Washington, Forenede Stater, 98405
        • MultiCare Medical Center (Tacoma General Hospital)
      • Tacoma, Washington, Forenede Stater, 98405
        • St. Joseph Medical Center
    • West Virginia
      • Morgantown, West Virginia, Forenede Stater, 26506-9157
        • West Virginia University Hospital
    • Wisconsin
      • La Crosse, Wisconsin, Forenede Stater, 54601
        • Franciscan Skemp Healthcare
      • Milwaukee, Wisconsin, Forenede Stater, 53226
        • Froedtert Hospital
      • Waukesha, Wisconsin, Forenede Stater, 53188
        • Waukesha Memorial Hospital
  • Frankrig
      • Angers, Frankrig, 49100
        • CHRU de Angers
      • Colmar Cedex, Frankrig, 66027
        • Clinique Saint Joseph
      • Eaubonne-Montmorency, Frankrig, 95601
        • Cardiologie Hopital Simone Veil
      • Haguenau, Frankrig, 67504
        • Centre Hospitalier de Haguenau
      • Nantes, Frankrig, 44000
        • CHRU de Nantes
      • Paris, Frankrig, 75010
        • Hôpital Lariboisière
      • Paris, Frankrig, 75018
        • Hôpital Bichat
      • Paris Cedex 13, Frankrig, 75743
        • Hopital a Pitie Salpetriere
      • Pessac, Frankrig, 33604
        • Hôpital du Haut Lévêque
      • Rennes, Frankrig, 35000
        • Hôpital Pontchaillou
      • Rouen, Frankrig, 76000
        • CHRU de Rouen
      • Saint Denis, Frankrig, 93200
        • Centre Cardiologique du Nord
      • Strasbourg, Frankrig, 67100
        • CHRU Hautepierre
      • Toulouse Cedex 9, Frankrig, 31059
        • Hopital Rangueil
      • Vandoeuvre les Nancy, Frankrig, 54511
        • Hopital d'adultes de Brabois (CHU de Nancy)
  • Holland
    • BR
      • Eindhovenb, BR, Holland, 5623 EJ
        • Catharina Hospital
    • LI
      • Maastricht, LI, Holland, 6229 HX
        • Academic Hospital Maastricht
    • NH
      • Alkmaar, NH, Holland, 1800 AM
        • Medeisch Centrum Alkmaar
      • Amsterdam, NH, Holland, 1081 HV
        • VUMC
      • Amsterdam, NH, Holland, 1091 HD
        • OLVG
    • OV
      • Zwolle, OV, Holland, 8011 JW
        • Isla Klinieken Location De Weezenlanden
    • UT
      • Nieuwegein, UT, Holland, 3435 CM
        • Sint Antonius Hospital
      • Ultrecht, UT, Holland, 3584 CX
        • University Medical Center Utrecht
    • ZH
      • Rotterdam, ZH, Holland, 3015 GD
        • Erasmus Medical Centre
      • Rotterdam, ZH, Holland, 3075 EA
        • Medisch Centrum Rijnmond-Zuid
  • Italien
      • Alessandria, Italien, 15100
        • A.O. SS. Antonio e Biagio e Cesare Arrigo
      • Bologna, Italien, 40128
        • Policlinico Sant'Orsola-Malpighi
      • Bolzano, Italien, 39100
        • Ospedale Centrale di Bolzano
      • Brescia, Italien, 25123
        • A.O. Spedali di Civili
      • Como, Italien, 22100
        • A.O. della Regione Lombardia Presidio Ospedaliero Sant'Anna
      • Lecco, Italien, 23900
        • Ospedale Alessandro Manzoni
      • Mantova, Italien, 46100
        • Azienda Ospedaliera Carlo Poma
      • Parma, Italien, 43100
        • Azienda Ospedaliera di Parma - Ospedale Maggiore
      • Pavia, Italien, 27100
        • Policlinico San Matteo - I.R.C.C.S.
      • Pesaro, Italien, 46100
        • A. O. S. Salvatore
      • Rimni, Italien, 47900
        • Osepdale degli Intermi
      • Roma, Italien, 00152
        • AO S. Camillo Forlanini
      • Torino, Italien, 10126
        • Cardiologia Universitaria
      • Treviso, Italien, 31100
        • Ospedale S. Maria di Ca'Foncello
    • Milano
      • San Donato Milanese, Milano, Italien, 20097
        • Centro E Malan
    • Padova
      • Cittadella, Padova, Italien, 35013
        • Presidio Ospedaliero di Cittadella
    • Reggio Emilla
      • Reggio Nell Emilia, Reggio Emilla, Italien, 42100
        • U.O. Cardiologia
  • New Zealand
      • Auckland, New Zealand, 1003
        • Auckland City Hospital
      • Wellington, New Zealand, 6002
        • Wellington Hospital
    • Canterbury
      • Christchurch, Canterbury, New Zealand, 8001
        • Christchurch Hospital
    • Otago
      • Dunedin, Otago, New Zealand, 9001
        • Dunedin Hospital
    • Waikoto
      • Hamilton, Waikoto, New Zealand, 2001
        • Waikato Hospital
  • Polen
      • Katowice - Ochojec, Polen, 40-635
        • I Klinika Kardiologii
      • Krakow, Polen, 31-202
        • Klinika Chorob Serca i Naczyn
      • Lodz, Polen, 91-347
        • II Katedra i Klinika Kardiologii
      • Warszawa, Polen, 04-628
        • I Klinika Choroby Wiencowej
      • Wroclaw, Polen, 50-420
        • SPZOZ Dolnoslaski Szpital Specjalistyczny
  • Portugal
      • Amadora, Portugal, 3700-376 Amadora
        • H. Fernando da Fonesca
      • Coimbra, Portugal, 3000-075 Coimbra
        • Hospitals da Universidade de Coimbra
      • Lisboa, Portugal, 1069-166 Lisboa
        • Hospital Curry Cabral
      • Lisboa, Portugal, 1600-190 LISBOA
        • H. Santa Maria
      • Porto, Portugal, 4200-319 Porto
        • Hospital Sao Joao - Servico de Cardiologia
      • Vila Nova De Gala, Portugal, 4434-502 Vila Nova de Gala
        • Centro Hospitalar de Vila Nova de Gala
    • Lisboa
      • Almada, Lisboa, Portugal, 2801-951 Almada
        • Hospital Garcia de Orta - Servico de Cardiologia
      • Carnaxide, Lisboa, Portugal, 270-134
        • Hospital Santa Cruz
  • Schweiz
      • Bassel, Schweiz, 4031
        • Kantonsspital Basel
    • Geneva
      • Geneva 14, Geneva, Schweiz, CH-1211
        • University Hospital of Geneva
    • Saint Gallen
      • St. Gallen, Saint Gallen, Schweiz, CH-9007
        • Kantonsspital St. Gallen
    • Thurgau
      • Kreuzlingen, Thurgau, Schweiz, 8280
        • Herzklinik Bodensee am Weinberg AG
    • Ticino
      • Lugano, Ticino, Schweiz, 6900
        • Cardiocentro Ticino
  • Spanien
      • Alicante, Spanien, 03010
        • Hospital General Universitario de Alicante
      • Barcelona, Spanien, 08036
        • Hospital Clinic I Provincial
      • Leon, Spanien, 24008
        • Hospital de León
      • Madrid, Spanien, 28040
        • Hospital Clinico San Carlos
      • Madrid, Spanien, 28007
        • Hospital General Universitario Gregorio Marañón
      • Madrid, Spanien, 28035
        • Hospital Puerta de Hierro
      • Malaga, Spanien, 29010
        • Hospital Clinico Universitario Virgen de La Victoria
      • Sevilla, Spanien, 41013
        • Hopspital Virgen del Rocio
    • Barcelona
      • L'Hospitalet de Llobregat, Barcelona, Spanien, 08907
        • Ciutat Sanitaria i Universitaria de Bellvitge
    • Murcia
      • El Palmar, Murcia, Spanien, 30120
        • Hospital Virgen da la Arrixaca
    • Navarra
      • Pamplona, Navarra, Spanien, 31008
        • Hospital de Navarra
  • Sverige
      • Umea, Sverige, SE-901-85
        • Universitetetssjukhuset Umea
      • Uppsala, Sverige
        • Uppsala University Hospital
  • Tjekkiet
      • Brno, Tjekkiet, 625 00
        • Interni kardiologicka klinika, Fakultni nemocnice Brno
      • Brno, Tjekkiet, 656 91
        • I. interni kardioangiologicka klinika, Fakultni nemocnice u Sv. Anny
      • Liberec, Tjekkiet, 460 63
        • Kardiologicke odd., Krajska neocnice Liberec
      • Olomouc, Tjekkiet, 775-20
        • I. Interni klinika, FN Olomouc
      • Ostrava, Tjekkiet, 708 52
        • Interni klinika, FNsP Ostrava
      • Pardubice, Tjekkiet, 532 03
        • Kardio-Troll sro and Krajska nemocnice Pardubice
      • Pardubice, Tjekkiet, 53203
        • Kardio-Troll sro and Krajska nemocnice Pardubice
      • Plzen, Tjekkiet, 304 60
        • I. Interni klinika, Fakultni nemocnice Plzen
      • Prague, Tjekkiet, 10034
        • Kardiocentrum, Fakultni nemocnice Kralovske Vinohrady
      • Prague, Tjekkiet, 128 08
        • II. Interni klinika, Vseobecna fakultni nemocnice
      • Prague, Tjekkiet, 150 30
        • Kardiologicke odd., Nemocnice Na Homoice
      • Prague, Tjekkiet, 15006
        • Kardiologicka klinika FN v Motole
      • Trinec, Tjekkiet, 739 61
        • Kardiocentrum, Nemocnice Podlesi sro
      • Zlin, Tjekkiet, 462 75
        • Interni klinika, Batova nemocnice
    • Ceske Budejovice
      • Caske Budejovice, Ceske Budejovice, Tjekkiet, 370 878
        • Kardiologicke odd. Nemocnice Ceske Budejovice as
    • Hradec Kralove
      • Kradec Kralove, Hradec Kralove, Tjekkiet, 500 05
        • I. Interni klinika, Fakultni nemocnice Hradec
    • Prague
      • Prague 4, Prague, Tjekkiet, 14021
        • Klinika kardiologie, IKEM
    • Usti Nad Labem
      • Labem, Usti Nad Labem, Tjekkiet, 401 13
        • Kardiologicke oddeleni, Masarykova nemocnice
  • Tyskland
      • Bad Oeynhausen, Tyskland, 32545
        • Universitätsklinik Der Ruhr-Universität Bochum
      • Berlin, Tyskland, 10967
        • Vivantes Klinikum Am Urban
      • Berlin, Tyskland, 10249
        • Vivantes Klinikkum im Friedrichshain
      • Hamburg, Tyskland, 20246
        • Universitätsklinikum Hamburg-Eppendorf
      • Hamburg, Tyskland, 20099
        • Allgemeines Krankenhaus St. Georg
    • Baden-Wurttemberg
      • Mannheim, Baden-Wurttemberg, Tyskland, 66167
        • Universitätsklinikum Mannheim
    • Bavaria
      • Augsburg, Bavaria, Tyskland, 86156
        • Klinikum Augsburg, Stenglinstr. 2.
      • Coburg, Bavaria, Tyskland, 96450
        • Klinikum Coburg
      • Munchen, Bavaria, Tyskland, 81925
        • Stadt Krankenhaus Muenchen-Bogenhausen
    • Hessen
      • Bad Nauheim, Hessen, Tyskland, 61231
        • Kerckhoff-Klinik Bad Anuheim
      • Kassel, Hessen, Tyskland, 34125
        • Stadt. Kliniken Kassel
    • Lower Saxony
      • Celle, Lower Saxony, Tyskland, 29223
        • Allgemeines Krankenhaus Celle
      • Gottingen, Lower Saxony, Tyskland, 37075
        • Herzzentrum Göttingen
    • Nordhein Westfalen
      • Dortmund, Nordhein Westfalen, Tyskland, 44137
        • St. Johannes Krankenhaus
      • Duisburg, Nordhein Westfalen, Tyskland, 47137
        • Herzzentrum Duisburg
    • Nordrhein Westfalen
      • Koln, Nordrhein Westfalen, Tyskland, 51109
        • Kliniken der Stadt Koln
      • Wuppertal, Nordrhein Westfalen, Tyskland, 42117
        • Helios Klinikum Wuppertal GmbH
    • North Rhine-Westphalia
      • Detmold, North Rhine-Westphalia, Tyskland, 32756
        • Klinikkum Lippe
    • Rhineland-Palatinate
      • Ludwigshafen, Rhineland-Palatinate, Tyskland, 67063
        • Klinikkum Ludwigshafen
    • Schleswig Holstein
      • Bad Segeberg, Schleswig Holstein, Tyskland, 23795
        • Herzzentrum
    • Schleswig-Holstein
      • Lubeck, Schleswig-Holstein, Tyskland, 23538
        • Universitatsklinik Lubeck
    • Thuringia
      • Jena, Thuringia, Tyskland, 07740
        • Klinik fur Innere Medizin 1
    • Wurrtemberg
      • Krozingen, Wurrtemberg, Tyskland, 79189
        • Herz-Zentrum Bad Krozingen
  • Østrig
      • Linz, Østrig, 4010
        • Krankenhaus der barmherzigen Schwestern
      • Wien, Østrig, 1090
        • Univ. Klinik f. Innere Medizin II
      • Wien, Østrig, 1171
        • Wilhelminenspital

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Beskrivelse

Inklusionskriterier:

  • Hjertesymptomer i mindst 20 minutter inden for de sidste 6 timer;
  • Vil gennemgå primær PCI;
  • Har EKG-bevis for akut højrisiko ST-elevation myokardieinfarkt;
  • Vil gerne og kan følges i mindst 12 måneder.

Ekskluderingskriterier:

  • Isoleret lavrisiko inferior myokardieinfarkt;
  • Modtaget fibrinolytisk terapi;
  • Historie om komplementmangel;
  • Mistænkt neisseriel infektion;
  • Deltagelse i anden undersøgelse;
  • Graviditet;
  • Tidligere tilmelding.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Behandling
  • Tildeling: Randomiseret
  • Interventionel model: Parallel tildeling
  • Maskning: Dobbelt

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Placebo komparator: 1
Placebo infusion
Medicin: Placebo infusion
bolusinfusion over en 10 minutters periode én gang
Eksperimentel: 2
Pexelizumab infusion
Medicin: Pexelizumab
Pexelizumab (2 mg/kg) intravenøst, bolus i 10 minutter én gang

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Tidsramme
Reduktion af alle dødsårsager
Tidsramme: dag 30
dag 30

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Procter and Gamble

Efterforskere

  • Studieleder: Thomas G Todaro, MD, JD, FACC, Procter and Gamble

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart

1. april 2004

Primær færdiggørelse (Faktiske)

1. maj 2007

Studieafslutning (Faktiske)

1. maj 2007

Datoer for studieregistrering

Først indsendt

14. september 2004

Først indsendt, der opfyldte QC-kriterier

15. september 2004

Først opslået (Anslået)

16. september 2004

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Anslået)

20. november 2023

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

17. november 2023

Sidst verificeret

1. november 2023

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • 2003056

Disse oplysninger blev hentet direkte fra webstedet clinicaltrials.gov uden ændringer. Hvis du har nogen anmodninger om at ændre, fjerne eller opdatere dine undersøgelsesoplysninger, bedes du kontakte register@clinicaltrials.gov. Så snart en ændring er implementeret på clinicaltrials.gov, vil denne også blive opdateret automatisk på vores hjemmeside .

Abonner