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Pexelizumab i forbindelse med angioplastikk ved akutt hjerteinfarkt (APEX-AMI)

17. november 2023 oppdatert av: Procter and Gamble

APEX-AMI - Pexelizumab i forbindelse med angioplastikk

Ved reperfusjonsbehandling ved akutt hjerteinfarkt ved bruk av primær perkutan intervensjon (PCI), kan kroppens eget betennelsessystem som involverer komplementkaskaden være skadelig. Denne studien vil teste sikkerheten og effekten av en ny komplementhemmer, pexelizumab, for å redusere dødeligheten etter 30 dager.

Studieoversikt

Status

Fullført

Forhold

Intervensjon / Behandling

Studietype

Intervensjonell

Registrering (Faktiske)

5745

Fase

  • Fase 3

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

  • Australia
    • Australian Capital Territory
      • Garran, Australian Capital Territory, Australia, 2605
        • Canberra Hospital
    • New South Wales
      • Concord, New South Wales, Australia, 2137
        • Concord Hospital
      • Gosford, New South Wales, Australia, 2250
        • Gosford Hospital
      • Kogarah, New South Wales, Australia, 2217
        • St. George Hospital
      • Liverpool, New South Wales, Australia, 2170
        • Liverpool Hospital
      • Randwick, New South Wales, Australia, 2031
        • Prince of Wales Hospital
      • St. Leonards, New South Wales, Australia, 2065
        • Royal North Shore Hospital
    • Queensland
      • Chermside, Queensland, Australia, 4032
        • Prince Charles Hospital
      • Douglas, Queensland, Australia, 4814
        • Townsville Hospital
      • Wooloong Abba, Queensland, Australia, 4102
        • Princess Alexandra Hospital
    • South Australia
      • Adelaide, South Australia, Australia, 5000
        • Royal Adelaide Hospital
      • Bedford Park, South Australia, Australia, 5042
        • Flinders Medical Centre
      • Woodville South, South Australia, Australia, 5011
        • The Queen Elizabeth Hospital
    • Victoria
      • Box Hill, Victoria, Australia, 3128
        • Box Hill Hospital
      • Box Hill, Victoria, Australia, 3084
        • Austin Hospital
      • Clayton, Victoria, Australia, 3162
        • Monash Medical Centre
      • Parkville, Victoria, Australia, 3050
        • Royal Melbourne Hospital
      • Richmond, Victoria, Australia, 3121
        • Victorian Heart Clinic
    • Western Australia
      • Fremantle, Western Australia, Australia, 6160
        • Fremantle Hospital
      • Nedlands, Western Australia, Australia, 6009
        • Sir Charles Gairdner Hospital
      • Perth, Western Australia, Australia, 6000
        • Royal Perth Hospital
  • Belgia
      • Antwerpen, Belgia, 2020
        • AZ Middelheim
      • Liege, Belgia, 4000
        • CHR de la Citadelle
    • Brabant
      • Leuven, Brabant, Belgia, 3000
        • U.Z. Gasthuisberg
    • Limburg
      • Genk, Limburg, Belgia, 3600
        • ZOL Campus Sint-Jan
    • Vlaanderen
      • Roeselare, Vlaanderen, Belgia, 8800
        • Helig Hartziekenhuis
  • Canada
    • Alberta
      • Calgary, Alberta, Canada, T2N 2W8
        • Foothills Medical Centre
      • Edmonton, Alberta, Canada, T6G 2B7
        • University of Alberta Hospital
    • British Columbia
      • Vancouver, British Columbia, Canada, V6Z 1Y6
        • St. Paul's Hospital
      • Vancouver, British Columbia, Canada, V5Z 1L8
        • Vancouver General Hospital
      • Victoria, British Columbia, Canada, V8R 4R2
        • Royal Jubilee Hospital
    • New Brunswick
      • Saint John, New Brunswick, Canada, E2L 4L2
        • Saint John Regional Hospital - New Brunswick Heart Centre
    • Newfoundland and Labrador
      • St. John's, Newfoundland and Labrador, Canada, A1B 3E4
        • General Hospital Health Sciences Centre
    • Ontario
      • Hamilton, Ontario, Canada, L8L 2X2
        • Hamilton General Hospital
      • Mississauga, Ontario, Canada, L58 2P7
        • Trillium Health Center
      • Toronto, Ontario, Canada, M4N 3M5
        • Sunnybrook & Women's Health Sciences Centre
    • Quebec
      • Montreal, Quebec, Canada, H4J 1C5
        • Hôpital Sacré-Coeur de Montréal
      • Montreal, Quebec, Canada, H1T 1C8
        • Montreal Heart Institute/Research Centre
      • Montreal, Quebec, Canada, H2L 4M1
        • Centre Hospitale de'Universite de Montreal (Pav Notre-Dame)_
      • Sainte-Foy, Quebec, Canada, G1V 4G5
        • Quebec Heart Institute/Laval Hospital
      • Sherbrooke, Quebec, Canada, J1H 5N4
        • Centre Hospitalier Universitaire de Sherbrooke
    • Saskatchewan
      • Regina, Saskatchewan, Canada, S4P 0W5
        • Regina General Hospital
  • Danmark
      • Odense, Danmark, 5000
        • Odense Universitets Hospital
    • Danmark
      • Aalborg, Danmark, Danmark, 9100
        • Aalborg Sygehus
      • Aarhus, Danmark, Danmark, 8200
        • Skejby Sygehus
      • Hellerup, Danmark, Danmark, 2900
        • Amtssygehuset i Gentofte
      • Kobenhavn, Danmark, Danmark, DK-2100
        • Rigshospitalet
  • Forente stater
    • Alabama
      • Huntsville, Alabama, Forente stater, 35801
        • Huntsville Hospital
    • Arizona
      • Phoenix, Arizona, Forente stater, 85054
        • Mayo Clinic Hospital
      • Phoenix, Arizona, Forente stater
        • North Phoenix Heart Center
      • Tucson, Arizona, Forente stater, 85741
        • Northwest Medical Center
    • Arkansas
      • Fort Smith, Arkansas, Forente stater, 72901
        • Sparks Regional Medical Center
      • Little Rock, Arkansas, Forente stater, 72211
        • Arkansas State Hospital
    • California
      • Beverly Hills, California, Forente stater, 90230
        • Brotman Medical Center
      • Burbank, California, Forente stater, 91505
        • Providence Saint Joseph Medical Center
      • Escondido, California, Forente stater, 92025
        • Palomar Medical Center
      • Los Angeles, California, Forente stater, 90033
        • Los Angeles Community Hospital
      • Modesto, California, Forente stater, 48201
        • Memorial Medical Center
      • Sacramento, California, Forente stater, 95825
        • Sutter Memorial Hospital
      • San Diego, California, Forente stater, 92103-8784
        • University of CA, San Diego Medical
      • Santa Rosa, California, Forente stater, 95403
        • Sutter Medical Center of Santa Rosa
      • Valencia, California, Forente stater, 91355
        • Providence Holy Cross Medical Center
    • Colorado
      • Denver, Colorado, Forente stater, 80262
        • University of Colorado Hospital
    • Connecticut
      • Bridgeport, Connecticut, Forente stater, 06606
        • St. Vincent Medical Center
      • Farmington, Connecticut, Forente stater, 06030-2202
        • University of Connecticut Health Center
      • New Haven, Connecticut, Forente stater, 06520
        • Yale - New Haven
    • District of Columbia
      • Washington, District of Columbia, Forente stater, 20037
        • George Washington University Hospital
    • Florida
      • Atlantis, Florida, Forente stater, 33462
        • JFK Medical Center
      • Clearwater, Florida, Forente stater, 33756
        • Morton Plant Hospital
      • Fort Lauderdale, Florida, Forente stater, 33308
        • North Ridge Medical Center
      • Jacksonville, Florida, Forente stater, 32224
        • St. Luke's Hospital
      • Melbourne, Florida, Forente stater, 32001
        • Health First Holmes Regional Medical Center
      • Orlando, Florida, Forente stater, 32803
        • Florida Heart Hospital
      • Sarasota, Florida, Forente stater, 34239
        • Sarasota Memorial Hospital
      • Tampa, Florida, Forente stater, 33613
        • University Community Hospital
    • Idaho
      • Boise, Idaho, Forente stater, 63704
        • St. Luke's Regional Medical Center
    • Illinois
      • Bannockburn, Illinois, Forente stater, 60015
        • Highland Park Hospital
      • Harvey, Illinois, Forente stater, 80426
        • Ingalls Hospital
      • Lombard, Illinois, Forente stater, 60148
        • Advocate Good Samaritan
      • Lombard, Illinois, Forente stater, 60148
        • Elmhurst Hospital
      • Moline, Illinois, Forente stater, 61265
        • Trinity Medical Center
      • Peoria, Illinois, Forente stater, 61603
        • Saint Francis Medical Center
      • Rock Island, Illinois, Forente stater, 61201
        • Trinity Medical Center
    • Indiana
      • Indianapolis, Indiana, Forente stater, 46202
        • Methodist Hospital
      • Indianapolis, Indiana, Forente stater, 46227
        • Community Hospital South
      • Indianapolis, Indiana, Forente stater, 46202
        • VAMC
      • Indianapolis, Indiana, Forente stater, 56250
        • The Indiana Heart Hospital
      • Munster, Indiana, Forente stater, 46321
        • Munster Community Hospital
    • Iowa
      • Des Moines, Iowa, Forente stater, 50314
        • Iowa Heart
    • Kansas
      • Wichita, Kansas, Forente stater, 67214
        • Via Christi Reginal Medical Center
    • Kentucky
      • Lexington, Kentucky, Forente stater, 40503
        • Central Baptist Hospital
      • Lexington, Kentucky, Forente stater, 40536-0200
        • University of Kentucky
      • Louisville, Kentucky, Forente stater, 40207
        • Baptist Hospital East
      • Louisville, Kentucky, Forente stater, 40202
        • The Jewish Hospital
    • Louisiana
      • Chalmette, Louisiana, Forente stater, 70043
        • Lousiana Heart Center
      • Lacombe, Louisiana, Forente stater, 70445
        • Lousiana Heart Hospital
      • New Orleans, Louisiana, Forente stater, 70112
        • Tulane University Hospital and Clinic
      • New Orleans, Louisiana, Forente stater, 70112
        • MCLNO at New Orleans University Campus
    • Maine
      • Bangor, Maine, Forente stater, 04401
        • Eastern Maine Medical Center
      • Portland, Maine, Forente stater, 04102
        • Maine Medical Center
    • Maryland
      • Towson, Maryland, Forente stater, 21204
        • St. Joseph Medical Center
    • Michigan
      • Dearborn, Michigan, Forente stater, 48123
        • Oakwood Hospital and Medical Center
      • Detroit, Michigan, Forente stater, 48202
        • Henry Ford Hospital
      • Detroit, Michigan, Forente stater, 48235
        • Sinai-Grace Hospital
      • Grand Rapids, Michigan, Forente stater, 49503
        • Spectrum Health
      • Kalamazoo, Michigan, Forente stater, 49048
        • Borgess Medical Center
      • Muskegon, Michigan, Forente stater, 49444
        • Mercy General Health Partners
      • Petoskey, Michigan, Forente stater, 49770
        • Northern Michigan Hospital
      • Pontiac, Michigan, Forente stater, 48341-2982
        • St. Joseph Mercy-Oakland
      • Royal Oak, Michigan, Forente stater, 48073
        • William Beaumont Hospital
      • Saginaw, Michigan, Forente stater, 48601
        • Covenant Medical Center
      • Saginaw, Michigan, Forente stater, 48601
        • Saint Mary Medical Center
      • Southfield, Michigan, Forente stater, 48075
        • Providence Hospital
      • Troy, Michigan, Forente stater, 48085
        • William Beaumont Hospital
      • Warren, Michigan, Forente stater, 48201
        • Harper University Hospital
    • Minnesota
      • Coon Rapids, Minnesota, Forente stater, 55433
        • Mercy Hospital
      • Duluth, Minnesota, Forente stater, 55805
        • St. Mary's Duluth Clinic Health System
      • Edina, Minnesota, Forente stater, 55435
        • Fairview Southdale Hospital
      • Minneapolis, Minnesota, Forente stater, 55407
        • Abbott Northwestern Hospital
      • Minneapolis, Minnesota, Forente stater, 55422
        • North Memorial Medical Center
      • Rochester, Minnesota, Forente stater, 55902
        • Saint Mary Hospital
      • Saint Cloud, Minnesota, Forente stater, 56303
        • St. Cloud Hospital
      • Saint Louis Park, Minnesota, Forente stater, 55426
        • Methodist Hospital
      • Saint Paul, Minnesota, Forente stater, 55102
        • Health East St. Joseph Hospital
    • Missouri
      • Columbia, Missouri, Forente stater, 65212
        • University of Missouri Health Sciences Center
      • Saint Louis, Missouri, Forente stater, 63110
        • St. Louis University Hospital
      • Saint Louis, Missouri, Forente stater, 63122
        • Barnes St. Peters Hospital
      • Springfield, Missouri, Forente stater, 65807
        • St. John's Hospital
    • Montana
      • Billings, Montana, Forente stater, 59101
        • Deaconess Billings Clinic
    • Nebraska
      • Lincoln, Nebraska, Forente stater, 68510
        • St. Elizabeth Medical Center
    • Nevada
      • Las Vegas, Nevada, Forente stater, 89109
        • Sunrise Hospital
    • New Jersey
      • Elizabeth, New Jersey, Forente stater, 07202
        • Trinitas Hospital
      • Fair Lawn, New Jersey, Forente stater, 07410
        • St. Joseph's Regional Medical Center
    • New Mexico
      • Albuquerque, New Mexico, Forente stater, 87102
        • New Mexico Heart Institute
    • New York
      • Albany, New York, Forente stater, 12211
        • Albany Medical Center
      • Bronx, New York, Forente stater, 10467
        • Monteflore Medical Center
      • Brooklyn, New York, Forente stater, 11219
        • Maimonides Medical Center
      • Johnson City, New York, Forente stater, 13790
        • Wilson Memorial Medical Center
      • Mineola, New York, Forente stater, 11504
        • Winthrop University Hospital
      • New York, New York, Forente stater, 10016
        • Bellevue Hospital Center
      • New York, New York, Forente stater, 10011
        • St. Vincent's Catholic Medical Center
      • Poughkeepsie, New York, Forente stater, 12601
        • Vassar Brothers Medical Center
      • Rochester, New York, Forente stater, 14621
        • Rochester General Hospital
      • Syracuse, New York, Forente stater, 13210
        • SUNY - Upstate Medical University
    • North Carolina
      • Charlotte, North Carolina, Forente stater, 28204
        • Presbyterian Hospital
      • Durham, North Carolina, Forente stater, 27705
        • Duke University Health Systems
      • Greensboro, North Carolina, Forente stater, 27401
        • Moses Cone Hospital/LeBauer Healthcare
      • Greenville, North Carolina, Forente stater, 27834
        • Pitt County Memorial Hospital
      • High Point, North Carolina, Forente stater, 27262
        • High Point Regional Health System
    • North Dakota
      • Minot, North Dakota, Forente stater, 58701
        • Trinity Hospital
    • Ohio
      • Akron, Ohio, Forente stater, 44307
        • Akron General Medical Center
      • Cincinnati, Ohio, Forente stater, 45242
        • Bethesda North Hospital
      • Cincinnati, Ohio, Forente stater, 45220
        • VAMC Cincinnati
      • Cincinnati, Ohio, Forente stater, 45267
        • The University Hospital
      • Cleveland, Ohio, Forente stater, 44195
        • Cleveland Clinic Foundation
      • Cleveland, Ohio, Forente stater, 44103
        • University Hospitals of Cleveland
      • Columbus, Ohio, Forente stater, 43214
        • MidWest Cardiology Research Foundation
      • Mansfield, Ohio, Forente stater, 44906
        • Med Central Mansfield
      • Zanesville, Ohio, Forente stater, 43701
        • Genesis Healthcare System
    • Oklahoma
      • Midwest City, Oklahoma, Forente stater, 73110
        • Midwest Regional Medical Center
      • Oklahoma City, Oklahoma, Forente stater, 73104
        • University of Oklahoma Health Sciences Center
      • Oklahoma City, Oklahoma, Forente stater, 73120
        • Oklahoma Heart Hospital
      • Oklahoma City, Oklahoma, Forente stater, 73112
        • INTEGRIS Baptist Medical Center, Inc.
      • Oklahoma City, Oklahoma, Forente stater, 73104
        • VA Medical Center
    • Oregon
      • Bend, Oregon, Forente stater, 97701
        • St. Charles Medical Center
      • Portland, Oregon, Forente stater, 97213
        • Providence Portland Medical Center
    • Pennsylvania
      • Allentown, Pennsylvania, Forente stater, 18105
        • Lehigh Valley Hospital
      • Danville, Pennsylvania, Forente stater, 17822-2160
        • Geisinger Medical Center
      • Davenport, Pennsylvania, Forente stater, 58803
        • Genesis Medical Center
      • Erie, Pennsylvania, Forente stater, 16550
        • Hamot Medical Center
      • Hershey, Pennsylvania, Forente stater, 17033
        • Penn State Milton S. Hershey Medical Center
      • Lancaster, Pennsylvania, Forente stater, 17604
        • Lancaster General Hospital
      • Philadelphia, Pennsylvania, Forente stater, 19104
        • Hospital of the University of Pennsylvania
      • Philadelphia, Pennsylvania, Forente stater, 19140
        • Temple University Hospital
      • Pittsburgh, Pennsylvania, Forente stater, 15212
        • Allegheny General Hospital
      • Pittsburgh, Pennsylvania, Forente stater, 15240
        • VA Pittsburgh Healthcare System
      • Pittsburgh, Pennsylvania, Forente stater, 15025
        • Jefferson Regional Medical Center
      • Pittsburgh, Pennsylvania, Forente stater, 15215
        • Western Pennsylvania Hospital
      • West Chester, Pennsylvania, Forente stater, 19380
        • The Chester County Hospital
      • York, Pennsylvania, Forente stater, 17405
        • York Hospital
    • Rhode Island
      • Providence, Rhode Island, Forente stater, 02903
        • Rhode Island Hospital
    • South Carolina
      • Columbia, South Carolina, Forente stater, 29203
        • Palmetto Richland Memorial Hospital
      • Columbia, South Carolina, Forente stater, 29204
        • Sisters of Charity Providence Hospitals
    • South Dakota
      • Rapid City, South Dakota, Forente stater, 57719
        • Rapid City Regional Hospital
      • Sioux Falls, South Dakota, Forente stater, 57108
        • Heart Hospital of South Dakota
    • Tennessee
      • Jackson, Tennessee, Forente stater, 38301
        • Jackson-Madison County General Hospital
      • Kingsport, Tennessee, Forente stater, 37660
        • Wellmont Holston Valley Medical Center
      • Knoxville, Tennessee, Forente stater, 37920
        • Baptist Hospital of East Tennessee
      • Knoxville, Tennessee, Forente stater, 37916
        • Fort Sanders Rgional Medical Center
      • Nashville, Tennessee, Forente stater, 37203
        • Centennial Medical Center
      • Oak Ridge, Tennessee, Forente stater, 37830
        • Methodist Medical Center
    • Texas
      • Amarillo, Texas, Forente stater, 79106
        • Northwest Texas Healthcare System
      • Austin, Texas, Forente stater, 78705
        • Seton Medical Center
      • Dallas, Texas, Forente stater, 75230
        • Medical City Dallas
      • Dallas, Texas, Forente stater, 75390
        • Parkland Health & Hospital System
      • Dallas, Texas, Forente stater, 57231
        • Presbyterian Hospital of Dallas
      • Dallas, Texas, Forente stater, 75390
        • Dallas Medical Center
      • Fort Sam Houston, Texas, Forente stater, 78234
        • Brooke Army Medical Center
      • Houston, Texas, Forente stater, 77030
        • Michael E. DeBakey VA Medical Center
      • Houston, Texas, Forente stater, 77030
        • Memorial Hermann Hospital
      • Houston, Texas, Forente stater, 77030
        • Ben Taub General Hospital
      • Houston, Texas, Forente stater, 77090
        • Houston Northwest Medical Center
      • Lubbock, Texas, Forente stater, 79410
        • Covenant Medical Center
      • San Antonio, Texas, Forente stater, 78217
        • Northeast Baptist Hospital
      • San Antonio, Texas, Forente stater, 78258
        • South Texas Veterans Health Care System Audie L. Murphy Division
      • Temple, Texas, Forente stater, 76508
        • Scott & White Memorial Hospital
      • Tyler, Texas, Forente stater, 75701
        • East Texas Medical Center
      • Tyler, Texas, Forente stater, 75701
        • Trinity Mother Frances Hospital
      • Victoria, Texas, Forente stater, 77901
        • Citizens Medical Center
      • Victoria, Texas, Forente stater, 77901
        • Detar Hospital
    • Utah
      • Murray, Utah, Forente stater, 84107
        • Cottonwood Hospital
    • Virginia
      • Alexandria, Virginia, Forente stater, 22306
        • Inova Alexandria Hospital
      • Charlottesville, Virginia, Forente stater, 22908
        • Universitiy of Virginia Health Science Center
      • Harrisonburg, Virginia, Forente stater, 22801
        • Rockingham Memorial Hospital
      • Lynchburg, Virginia, Forente stater, 24501
        • Lynchburg General Hospital
      • Richmond, Virginia, Forente stater
        • Herrico Doctors' Hospital - Forest
      • Virginia Beach, Virginia, Forente stater, 23454
        • Sentara Virginia Beach General Hospital
      • Winchester, Virginia, Forente stater, 22601
        • Winchester Medical Center
    • Washington
      • Bellevue, Washington, Forente stater, 98004
        • Overtake Hospital Medical Center
      • Mount Vernon, Washington, Forente stater, 98274
        • Skagit Valley Hospital
      • Seattle, Washington, Forente stater, 98104
        • Harborview Medical Center
      • Tacoma, Washington, Forente stater, 98405
        • MultiCare Medical Center (Tacoma General Hospital)
      • Tacoma, Washington, Forente stater, 98405
        • St. Joseph Medical Center
    • West Virginia
      • Morgantown, West Virginia, Forente stater, 26506-9157
        • West Virginia University Hospital
    • Wisconsin
      • La Crosse, Wisconsin, Forente stater, 54601
        • Franciscan Skemp Healthcare
      • Milwaukee, Wisconsin, Forente stater, 53226
        • Froedtert Hospital
      • Waukesha, Wisconsin, Forente stater, 53188
        • Waukesha Memorial Hospital
  • Frankrike
      • Angers, Frankrike, 49100
        • CHRU de Angers
      • Colmar Cedex, Frankrike, 66027
        • Clinique Saint Joseph
      • Eaubonne-Montmorency, Frankrike, 95601
        • Cardiologie Hopital Simone Veil
      • Haguenau, Frankrike, 67504
        • Centre Hospitalier de Haguenau
      • Nantes, Frankrike, 44000
        • CHRU de Nantes
      • Paris, Frankrike, 75010
        • Hopital Lariboisiere
      • Paris, Frankrike, 75018
        • Hopital Bichat
      • Paris Cedex 13, Frankrike, 75743
        • Hopital a Pitie Salpetriere
      • Pessac, Frankrike, 33604
        • Hopital du Haut Leveque
      • Rennes, Frankrike, 35000
        • Hopital Pontchaillou
      • Rouen, Frankrike, 76000
        • CHRU de Rouen
      • Saint Denis, Frankrike, 93200
        • Centre Cardiologique du Nord
      • Strasbourg, Frankrike, 67100
        • CHRU Hautepierre
      • Toulouse Cedex 9, Frankrike, 31059
        • Hôpital Rangueil
      • Vandoeuvre les Nancy, Frankrike, 54511
        • Hopital d'adultes de Brabois (CHU de Nancy)
  • Italia
      • Alessandria, Italia, 15100
        • A.O. SS. Antonio e Biagio e Cesare Arrigo
      • Bologna, Italia, 40128
        • Policlinico Sant'Orsola-Malpighi
      • Bolzano, Italia, 39100
        • Ospedale Centrale di Bolzano
      • Brescia, Italia, 25123
        • A.O. Spedali di Civili
      • Como, Italia, 22100
        • A.O. della Regione Lombardia Presidio Ospedaliero Sant'Anna
      • Lecco, Italia, 23900
        • Ospedale Alessandro Manzoni
      • Mantova, Italia, 46100
        • Azienda Ospedaliera Carlo Poma
      • Parma, Italia, 43100
        • Azienda Ospedaliera di Parma - Ospedale Maggiore
      • Pavia, Italia, 27100
        • Policlinico San Matteo - I.R.C.C.S.
      • Pesaro, Italia, 46100
        • A. O. S. Salvatore
      • Rimni, Italia, 47900
        • Osepdale degli Intermi
      • Roma, Italia, 00152
        • AO S. Camillo Forlanini
      • Torino, Italia, 10126
        • Cardiologia Universitaria
      • Treviso, Italia, 31100
        • Ospedale S. Maria di Ca'Foncello
    • Milano
      • San Donato Milanese, Milano, Italia, 20097
        • Centro E Malan
    • Padova
      • Cittadella, Padova, Italia, 35013
        • Presidio Ospedaliero di Cittadella
    • Reggio Emilla
      • Reggio Nell Emilia, Reggio Emilla, Italia, 42100
        • U.O. Cardiologia
  • Nederland
    • BR
      • Eindhovenb, BR, Nederland, 5623 EJ
        • Catharina Hospital
    • LI
      • Maastricht, LI, Nederland, 6229 HX
        • Academic Hospital Maastricht
    • NH
      • Alkmaar, NH, Nederland, 1800 AM
        • Medeisch Centrum Alkmaar
      • Amsterdam, NH, Nederland, 1081 HV
        • VUmc
      • Amsterdam, NH, Nederland, 1091 HD
        • OLVG
    • OV
      • Zwolle, OV, Nederland, 8011 JW
        • Isla Klinieken Location De Weezenlanden
    • UT
      • Nieuwegein, UT, Nederland, 3435 CM
        • Sint Antonius Hospital
      • Ultrecht, UT, Nederland, 3584 CX
        • University Medical Center Utrecht
    • ZH
      • Rotterdam, ZH, Nederland, 3015 GD
        • Erasmus Medical Centre
      • Rotterdam, ZH, Nederland, 3075 EA
        • Medisch Centrum Rijnmond-Zuid
  • New Zealand
      • Auckland, New Zealand, 1003
        • Auckland City Hospital
      • Wellington, New Zealand, 6002
        • Wellington Hospital
    • Canterbury
      • Christchurch, Canterbury, New Zealand, 8001
        • Christchurch Hospital
    • Otago
      • Dunedin, Otago, New Zealand, 9001
        • Dunedin Hospital
    • Waikoto
      • Hamilton, Waikoto, New Zealand, 2001
        • Waikato Hospital
  • Polen
      • Katowice - Ochojec, Polen, 40-635
        • I Klinika Kardiologii
      • Krakow, Polen, 31-202
        • Klinika Chorob Serca i Naczyn
      • Lodz, Polen, 91-347
        • II Katedra i Klinika Kardiologii
      • Warszawa, Polen, 04-628
        • I Klinika Choroby Wiencowej
      • Wroclaw, Polen, 50-420
        • SPZOZ Dolnoslaski Szpital Specjalistyczny
  • Portugal
      • Amadora, Portugal, 3700-376 Amadora
        • H. Fernando da Fonesca
      • Coimbra, Portugal, 3000-075 Coimbra
        • Hospitals da Universidade de Coimbra
      • Lisboa, Portugal, 1069-166 Lisboa
        • Hospital Curry Cabral
      • Lisboa, Portugal, 1600-190 LISBOA
        • H. Santa Maria
      • Porto, Portugal, 4200-319 Porto
        • Hospital Sao Joao - Servico de Cardiologia
      • Vila Nova De Gala, Portugal, 4434-502 Vila Nova de Gala
        • Centro Hospitalar de Vila Nova de Gala
    • Lisboa
      • Almada, Lisboa, Portugal, 2801-951 Almada
        • Hospital Garcia de Orta - Servico de Cardiologia
      • Carnaxide, Lisboa, Portugal, 270-134
        • Hospital Santa Cruz
  • Spania
      • Alicante, Spania, 03010
        • Hospital General Universitario de Alicante
      • Barcelona, Spania, 08036
        • Hospital Clinic I Provincial
      • Leon, Spania, 24008
        • Hospital de León
      • Madrid, Spania, 28040
        • Hospital Clinico San Carlos
      • Madrid, Spania, 28007
        • Hospital General Universitario Gregorio Marañón
      • Madrid, Spania, 28035
        • Hospital Puerta de Hierro
      • Malaga, Spania, 29010
        • Hospital Clinico Universitario Virgen de la Victoria
      • Sevilla, Spania, 41013
        • Hopspital Virgen del Rocio
    • Barcelona
      • L'Hospitalet de Llobregat, Barcelona, Spania, 08907
        • Ciutat Sanitaria i Universitaria de Bellvitge
    • Murcia
      • El Palmar, Murcia, Spania, 30120
        • Hospital Virgen da la Arrixaca
    • Navarra
      • Pamplona, Navarra, Spania, 31008
        • Hospital De Navarra
  • Sveits
      • Bassel, Sveits, 4031
        • Kantonsspital Basel
    • Geneva
      • Geneva 14, Geneva, Sveits, CH-1211
        • University Hospital of Geneva
    • Saint Gallen
      • St. Gallen, Saint Gallen, Sveits, CH-9007
        • Kantonsspital St. Gallen
    • Thurgau
      • Kreuzlingen, Thurgau, Sveits, 8280
        • Herzklinik Bodensee am Weinberg AG
    • Ticino
      • Lugano, Ticino, Sveits, 6900
        • Cardiocentro Ticino
  • Sverige
      • Umea, Sverige, SE-901-85
        • Universitetetssjukhuset Umea
      • Uppsala, Sverige
        • Uppsala University Hospital
  • Tsjekkia
      • Brno, Tsjekkia, 625 00
        • Interni kardiologicka klinika, Fakultni nemocnice Brno
      • Brno, Tsjekkia, 656 91
        • I. interni kardioangiologicka klinika, Fakultni nemocnice u Sv. Anny
      • Liberec, Tsjekkia, 460 63
        • Kardiologicke odd., Krajska neocnice Liberec
      • Olomouc, Tsjekkia, 775-20
        • I. Interni klinika, FN Olomouc
      • Ostrava, Tsjekkia, 708 52
        • Interni klinika, FNsP Ostrava
      • Pardubice, Tsjekkia, 532 03
        • Kardio-Troll sro and Krajska nemocnice Pardubice
      • Pardubice, Tsjekkia, 53203
        • Kardio-Troll sro and Krajska nemocnice Pardubice
      • Plzen, Tsjekkia, 304 60
        • I. Interni klinika, Fakultni nemocnice Plzen
      • Prague, Tsjekkia, 10034
        • Kardiocentrum, Fakultni nemocnice Kralovske Vinohrady
      • Prague, Tsjekkia, 128 08
        • II. Interni klinika, Vseobecna fakultni nemocnice
      • Prague, Tsjekkia, 150 30
        • Kardiologicke odd., Nemocnice Na Homoice
      • Prague, Tsjekkia, 15006
        • Kardiologicka klinika FN v Motole
      • Trinec, Tsjekkia, 739 61
        • Kardiocentrum, Nemocnice Podlesi sro
      • Zlin, Tsjekkia, 462 75
        • Interni klinika, Batova nemocnice
    • Ceske Budejovice
      • Caske Budejovice, Ceske Budejovice, Tsjekkia, 370 878
        • Kardiologicke odd. Nemocnice Ceske Budejovice as
    • Hradec Kralove
      • Kradec Kralove, Hradec Kralove, Tsjekkia, 500 05
        • I. Interni klinika, Fakultni nemocnice Hradec
    • Prague
      • Prague 4, Prague, Tsjekkia, 14021
        • Klinika kardiologie, IKEM
    • Usti Nad Labem
      • Labem, Usti Nad Labem, Tsjekkia, 401 13
        • Kardiologicke oddeleni, Masarykova nemocnice
  • Tyskland
      • Bad Oeynhausen, Tyskland, 32545
        • Universitätsklinik der Ruhr-Universität Bochum
      • Berlin, Tyskland, 10967
        • Vivantes Klinikum am Urban
      • Berlin, Tyskland, 10249
        • Vivantes Klinikkum im Friedrichshain
      • Hamburg, Tyskland, 20246
        • Universitätsklinikum Hamburg-Eppendorf
      • Hamburg, Tyskland, 20099
        • Allgemeines Krankenhaus St. Georg
    • Baden-Wurttemberg
      • Mannheim, Baden-Wurttemberg, Tyskland, 66167
        • Universitätsklinikum Mannheim
    • Bavaria
      • Augsburg, Bavaria, Tyskland, 86156
        • Klinikum Augsburg, Stenglinstr. 2.
      • Coburg, Bavaria, Tyskland, 96450
        • Klinikum Coburg
      • Munchen, Bavaria, Tyskland, 81925
        • Stadt Krankenhaus Muenchen-Bogenhausen
    • Hessen
      • Bad Nauheim, Hessen, Tyskland, 61231
        • Kerckhoff-Klinik Bad Anuheim
      • Kassel, Hessen, Tyskland, 34125
        • Stadt. Kliniken Kassel
    • Lower Saxony
      • Celle, Lower Saxony, Tyskland, 29223
        • Allgemeines Krankenhaus Celle
      • Gottingen, Lower Saxony, Tyskland, 37075
        • Herzzentrum Gottingen
    • Nordhein Westfalen
      • Dortmund, Nordhein Westfalen, Tyskland, 44137
        • St. Johannes Krankenhaus
      • Duisburg, Nordhein Westfalen, Tyskland, 47137
        • Herzzentrum Duisburg
    • Nordrhein Westfalen
      • Koln, Nordrhein Westfalen, Tyskland, 51109
        • Kliniken der Stadt Köln
      • Wuppertal, Nordrhein Westfalen, Tyskland, 42117
        • HELIOS Klinikum Wuppertal GmbH
    • North Rhine-Westphalia
      • Detmold, North Rhine-Westphalia, Tyskland, 32756
        • Klinikkum Lippe
    • Rhineland-Palatinate
      • Ludwigshafen, Rhineland-Palatinate, Tyskland, 67063
        • Klinikkum Ludwigshafen
    • Schleswig Holstein
      • Bad Segeberg, Schleswig Holstein, Tyskland, 23795
        • Herzzentrum
    • Schleswig-Holstein
      • Lubeck, Schleswig-Holstein, Tyskland, 23538
        • Universitatsklinik Lubeck
    • Thuringia
      • Jena, Thuringia, Tyskland, 07740
        • Klinik fur Innere Medizin 1
    • Wurrtemberg
      • Krozingen, Wurrtemberg, Tyskland, 79189
        • Herz-Zentrum Bad Krozingen
  • Østerrike
      • Linz, Østerrike, 4010
        • Krankenhaus der barmherzigen Schwestern
      • Wien, Østerrike, 1090
        • Univ. Klinik f. Innere Medizin II
      • Wien, Østerrike, 1171
        • Wilhelminenspital

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

18 år og eldre (Voksen, Eldre voksen)

Tar imot friske frivillige

Nei

Beskrivelse

Inklusjonskriterier:

  • Hjertesymptomer i minst 20 minutter i løpet av de siste 6 timene;
  • Vil gjennomgå primær PCI;
  • Har EKG-bevis på akutt hjerteinfarkt med høy risiko ST-elevasjon;
  • Villig og kan følges i minst 12 måneder.

Ekskluderingskriterier:

  • Isolert lavrisiko hjerteinfarkt av inferior vegg;
  • Mottatt fibrinolytisk terapi;
  • Historie om komplementmangel;
  • Mistenkt neisseriell infeksjon;
  • Delta i andre undersøkelser;
  • Svangerskap;
  • Tidligere påmelding.

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

  • Primært formål: Behandling
  • Tildeling: Randomisert
  • Intervensjonsmodell: Parallell tildeling
  • Masking: Dobbelt

Våpen og intervensjoner

Deltakergruppe / Arm
Intervensjon / Behandling
Placebo komparator: 1
Placebo infusjon
Legemiddel: Placebo infusjon
bolusinfusjon over en 10-minutters periode én gang
Eksperimentell: 2
Pexelizumab infusjon
Legemiddel: Pexelizumab
Pexelizumab (2 mg/kg) intravenøst, bolus i 10 minutter én gang

Hva måler studien?

Primære resultatmål

Resultatmål
Tidsramme
Reduksjon av alle dødelighetsårsaker
Tidsramme: dag 30
dag 30

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

Procter and Gamble

Etterforskere

  • Studieleder: Thomas G Todaro, MD, JD, FACC, Procter and Gamble

Publikasjoner og nyttige lenker

Den som er ansvarlig for å legge inn informasjon om studien leverer frivillig disse publikasjonene. Disse kan handle om alt relatert til studiet.

Generelle publikasjoner

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart

1. april 2004

Primær fullføring (Faktiske)

1. mai 2007

Studiet fullført (Faktiske)

1. mai 2007

Datoer for studieregistrering

Først innsendt

14. september 2004

Først innsendt som oppfylte QC-kriteriene

15. september 2004

Først lagt ut (Antatt)

16. september 2004

Oppdateringer av studieposter

Sist oppdatering lagt ut (Antatt)

20. november 2023

Siste oppdatering sendt inn som oppfylte QC-kriteriene

17. november 2023

Sist bekreftet

1. november 2023

Mer informasjon

Begreper knyttet til denne studien

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

  • 2003056

Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .

Kliniske studier på Akutt hjerteinfarkt

Kliniske studier på Placebo infusjon

Søk i lignende forsøk

Sponsorer og samarbeidspartnere

Medisinsk tilstand

Legemiddelintervensjoner

CROs by country

CROs in Mauritius

Forhold

Sjeldne sykdommer

Legemiddelintervensjoner

Kosttilskudd

Sponsor / samarbeidspartnere

Steder

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