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En undersøgelse af Milvexian Versus Apixaban hos deltagere med atrieflimren (LIBREXIA-AF)

4. juni 2026 opdateret af: Janssen Research & Development, LLC

En fase 3, randomiseret, dobbeltblind, dobbeltdummy, parallel gruppe, aktiv-kontrolleret undersøgelse til evaluering af effektiviteten og sikkerheden af Milvexian, en oral faktor XIa-hæmmer, versus Apixaban hos deltagere med atrieflimren

Formålet med denne undersøgelse er at vurdere, om milvexian er mindst lige så effektiv som apixaban til at reducere risikoen for det sammensatte slagtilfælde og systemisk emboli i det ikke-centrale nervesystem (CNS).

Studieoversigt

Status

Aktiv, ikke rekrutterende

Betingelser

Atrieflimren

Intervention / Behandling

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

20284

Fase

Fase 3

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

Argentina
- - Bahía Blanca, Argentina, B8000FTD
    - Instituto de Investigaciones Clinicas Bahia Blanca
  - Buenos Aires, Argentina, C1440CFD
    - CEMEDIC
  - Buenos Aires, Argentina, C1187AAN
    - Sanatorio Finochietto
  - Buenos Aires, Argentina, C1199
    - Hospital Italiano de Buenos Aires
  - Buenos Aires, Argentina, C1061AAS
    - CIPREC
  - Buenos Aires, Argentina, 1060
    - CEDIC Centro de Investigaciones Clinicas
  - CABA, Argentina, C1056ABJ
    - CINME Centro de Investigaciones Metabólicas
  - Capital Federal, Argentina, C1118AAE
    - Clínica y Maternidad Suizo Argentina
  - Ciudad Autonoma Buenos Aires, Argentina, C1093AAS
    - Fundacion Favaloro
  - Ciudad Autonoma Buenos Aires, Argentina, 1406
    - Consultorio Dr. Litvak Bruno
  - Ciudad Autonoma Buenos Aires, Argentina, 1428
    - Instituto Cardiovascular de Buenos Aires
  - Ciudad Autonoma Buenos Aires, Argentina, 1425
    - Consultorios Asociados de Endocrinología e Investigación Clínica Aplicada
  - Ciudad Autonoma Buenos Aires, Argentina, C1430CKE
    - Glenny Corp. S.A. - Bioclinica Argentina
  - Ciudad de Buenos Aires, Argentina, C1430EGF
    - Clinica Adventista Belgrano
  - Ciudadela, Argentina, 1702
    - Instituto Médico Elsa Pérez I.M.E.P
  - Cordooba, Argentina, X5003DCP
    - Centro Médico Colón
  - Coronel Suárez, Argentina, B7540GHD
    - Clinica Coronel Suárez
  - Córdoba, Argentina, X5000JHQ
    - Sanatorio Allende
  - Córdoba, Argentina, X5004BAL
    - Hospital Italiano de Cordoba
  - Córdoba, Argentina, 5000
    - Hospital San Roque
  - Córdoba, Argentina, X5003DCE
    - Instituto Médico DAMIC
  - Córdoba, Argentina, X5000AVE
    - CIDIM-Centro Integral de Diagnostico por Imagenes Marchegiani
  - Córdoba, Argentina, 5000
    - Clínica Privada Vélez Sarsfield
  - Córdoba, Argentina, X5000AAW
    - Instituto de Investigaciones Clínicas Córdoba
  - Córdoba, Argentina, X5006IKK
    - Centro Medico Luquez
  - Córdoba, Argentina, 5000
    - Clínica Colombo
  - Córdoba, Argentina, X5002HWE
    - Instituto Privado De Especialidades Medicas S.A. Fundacion J Robert Cade
  - Córdoba, Argentina, X5004CDT
    - Hospital Cordoba
  - Godoy Cruz, Argentina, 5501
    - CIPADI
  - Junín, Argentina, B6000BHA
    - Centro Medico Lebensohn
  - Mar del Plata, Argentina, B7600FZN
    - Instituto de Investigaciones Clinicas Mar del Plata
  - Mar del Plata, Argentina, B7600FYK
    - Centro de Investigaciones Medicas Mar Del Plata
  - Mendoza, Argentina, 5500
    - Fundación Scherbovsky
  - Quilmes, Argentina, B1878GEG
    - Instituto de Investigaciones Clinicas Quilmes
  - Ramos Mejía, Argentina, B1704ETD
    - DIM Clinica Privada
  - Rosario, Argentina, S2000SDV
    - Sanatorio Parque
  - Rosario, Argentina, 2000
    - Sanatorio Britanico S.A.
  - Rosario, Argentina, 2000
    - Sanatorio de la Mujer
  - Rosario, Argentina, S2000BIF
    - Instituto de Investigaciones Clinicas de Rosario
  - Salta, Argentina, 4400
    - Centro de Investigaciones Clinicas Salta
  - Salta, Argentina, 4400
    - Centro Cardiovascular Salta
  - San Juan, Argentina, 5400
    - Investigaciones Clinicas Cuyo
  - San Miguel de Tucumán, Argentina, T4000ICL
    - Investigaciones Clinicas Tucuman
  - San Nicolás, Argentina, 2900
    - Instituto de Investigaciones Clinicas San Nicolas
  - Santa Fe, Argentina, 3000
    - Centro de Investigaciones Clinicas del Litoral
  - Santa Fe, Argentina, S3000EOZ
    - Hospital Provincial Dr. Jose Maria Cullen
  - Temperley, Argentina, B1834GUK
    - Centro de Investigaciones Medicas Temperley
  - Venado Tuerto, Argentina, S2600KUE
    - Sanatorio San Martin
  - Villa María, Argentina, X5900JKA
    - Clinica Privada Fusavim SRL
  - Zárate, Argentina, 2800
    - Instituto de Investigaciones Clinicas Zarate
Australien
- - Adelaide, Australien, 5042
    - Flinders Medical Centre
  - Brisbane, Australien, 4066
    - Advara HeartCare Wesley
  - Concord, Australien, 2139
    - Concord Repatriation General Hospital
  - Frankston, Australien, 3199
    - Peninsula Heart Center
  - Garran, Australien, 2605
    - The Canberra Hospital
  - Herston, Australien, 4029
    - Royal Brisbane and Women's Hospital
  - Joondalup, Australien, 6027
    - GenesisCare Joondalup-Shenton House
  - Kotara, Australien, 2289
    - Novatrials
  - Leabrook, Australien, 5068
    - GenesisCare
  - Liverpool, Australien, 2170
    - Liverpool Hospital
  - Milton, Australien, 4064
    - Core Research Group
  - Taringa, Australien, 4068
    - AusTrials Tarragindi
Belgien
- - Aalst, Belgien, 9300
    - Algemeen Stedelijk Ziekenhuis
  - Antwerp, Belgien, 2020
    - ZNA Middelheim
  - Arlon, Belgien, 6700
    - CSL Arlon
  - Brussels, Belgien, 1070
    - CUB Hôpital Erasme
  - Brussels, Belgien, 1020
    - C.H.U. Brugmann
  - Dendermonde, Belgien, 9200
    - AZ Sint-Blasius
  - Edegem, Belgien, 2650
    - UZA
  - Herk-de-Stad, Belgien, 3540
    - Jessa Ziekenhuis - Campus St.-Ursula
  - La Louvière, Belgien, 7100
    - Chu Tivoli
  - Leuven, Belgien, 3000
    - UZ Leuven
  - Mechelen, Belgien, 97770
    - AZ Sint-Maarten
  - Mol, Belgien, 2400
    - Heilig Hart Ziekenhuis Lier
  - Roeselare, Belgien, 8800
    - AZ Delta vzw
  - Turnhout, Belgien, 2900
    - AZ Turnhout
Brasilien
- - Belo Horizonte, Brasilien, 30150-240
    - Cardresearch - Cardiologia Assistencial
  - Belo Horizonte, Brasilien, 30140-062
    - Hospital Vera Cruz
  - Belo Horizonte, Brasilien, 30110-934
    - Hospital Felicio Rocho
  - Botucatu, Brasilien, 18618-686
    - Fundacao para o Desenvolvimento Medico Hospitalar (UNESP Botucatu)
  - Brasília, Brasilien, 70390-700
    - Rede D or Sao Luiz S A Hospital do Coracao do Brasil
  - Brasília, Brasilien, 70710 149
    - Centro de Cardiologia Clinica e Pesquisa Doutora Juliana Souza Ltda CECAP Centro de Cardiologia Clinica
  - Campina Grande do Sul, Brasilien, 83430-000
    - Sociedade Hospitalar Angelina Caron
  - Campinas, Brasilien, 13060-080
    - Instituto de Pesquisa clinica de Campinas
  - Campinas, Brasilien, 13010-001
    - C.E.C.-Centro Especializado em Cardiologia Ltda.- Loema Medicina e Bem Estar
  - Canoas, Brasilien, 92425-900
    - Hospital Universitario
  - Criciúma, Brasilien, 88811-508
    - Sociedade Literaria e Caritativa Santo Agostinho Hospital Sao Jose
  - Curitiba, Brasilien, 80320-320
    - Hospital Cardiológico Costantini
  - Curitiba, Brasilien, 80010-030
    - Irmandade Santa Casa de Misericórdia de Curitiba -Pontifícia Universidade Católica do Paraná-PUCPR
  - Curitiba, Brasilien, 80730-150
    - Núcleo de Pesquisa Clinica
  - Goiânia, Brasilien, 74605-020
    - Universidade Federal de Goias - Hospital das Clinicas da UFG
  - Marília, Brasilien, 17515-000
    - Instituto do Coracao de Marília
  - Marília, Brasilien, 17515-000
    - Irmandade da Santa Casa de Misericórdia de Marília
  - Natal, Brasilien, 59020-035
    - Hemocardio SS Ltda
  - Passo Fundo, Brasilien, 99010-120
    - Instituto Mederi de Pesquisa e Saude
  - Pelotas, Brasilien, 96015-290
    - Santa Casa de Misericordia de Pelotas
  - Porto Alegre, Brasilien, 90035-903
    - Hospital das Clinicas de Porto Alegre
  - Porto Alegre, Brasilien, 90160-093
    - Hospital Ernesto Dornelles
  - Porto Alegre, Brasilien, 90035-001
    - Associação Hospitalar Moinhos de Vento
  - Porto Alegre, Brasilien, 90620-001
    - Fundacao Universitaria de Cardiologia
  - Porto Alegre, Brasilien, 90020 090
    - Irmandade da Santa Casa de Misericórdia de Porto Alegre
  - Porto Alegre, Brasilien, 90110-270
    - IMV Pesquisa Cardiologica Sociedade Simples HMD COR l
  - Recife, Brasilien, 50100-060
    - Pro Cardiaco Pronto Socorro Cardiologico
  - Recife, Brasilien, 52051-380
    - Secretaria de Saude Hospital Agamenon Magalhaes
  - Ribeirão Preto, Brasilien, 14098-900
    - Hospital Das Clinicas Da Faculdade De Medicina De RPUSP HCRP
  - Rio de Janeiro, Brasilien, 22061-080
    - Impar Servicos Hospitalares S/A
  - Salvador, Brasilien, 41810-010
    - Fundacao Bahiana de Cardiologia
  - Salvador, Brasilien, 40170-130
    - Instituto CardioPulmonar
  - Santo André, Brasilien, 09080-110
    - Pesquisare Saude
  - São José, Brasilien, 88103-460
    - Instituto de Cardiologia de Santa Catarina
  - São José do Rio Preto, Brasilien, 15090-000
    - Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base
  - São Paulo, Brasilien, 05403-000
    - Hospital das Clinicas da Faculdade de Medicina da USP
  - São Paulo, Brasilien, 04012-909
    - Instituto Dante Pazzanese de Cardiologia
  - São Paulo, Brasilien, 01323-903
    - Hospital Alemao Oswaldo Cruz
  - São Paulo, Brasilien, 01221-020
    - Irmandade Santa Casa de Misericordia de Sao Paulo
  - São Paulo, Brasilien, 01323 000
    - FGM Clinica Paulista de Doencas Cardiovasculares Ltda IPDC Cardiologia
  - Tatuí, Brasilien, 18270-170
    - Instituto de Moléstias Cardiovasculares Tatuí
  - Uberaba, Brasilien
    - HC-UFTM - Hospital de Clínicas da Universidade Federal do Triângulo Mineiro
  - Vitória, Brasilien, 29702-020
    - Clinica Cardioped Ltda
  - Vitória, Brasilien, 29055-450
    - CEDOES
  - Votuporanga, Brasilien, 15500-003
    - Santa Casa de Misericórdia de Votuporanga
Bulgarien
- - Blagoevgrad, Bulgarien, 2700
    - MHAT Puls
  - Burgas, Bulgarien
    - MC 4Life Ltd
  - Dimitrovgrad, Bulgarien, 6400
    - Medical Center Diamedical
  - Dimitrovgrad, Bulgarien, 6400
    - MHAT St. Ekaterina
  - Dupnitsa, Bulgarien, 2600
    - Medical Centre Asklepii OOD
  - Gabrovo, Bulgarien, 5300
    - Multiprofile Hospital for Active Treatment Dr. Tota Venkova
  - Haskovo, Bulgarien, 6300
    - Multiprofile Hospital for Active Treatment - Haskovo
  - Kardzhali, Bulgarien, 6600
    - Medical Center Rodopimed EOOD
  - Pazardzhik, Bulgarien, 44000
    - UMHAT 'Pulmed' OOD- MS 'Zdrave' - Pazardzhik
  - Pleven, Bulgarien, 5800
    - UMHAT 'Dr. Georgi Stranski', EAD
  - Pleven, Bulgarien, 5800
    - Medical Center Medconsult-Pleven
  - Pleven, Bulgarien, 5800
    - UMHAT 'Heart and Brain Center for Excellence'
  - Pleven, Bulgarien, 5300
    - Exacta Medica
  - Plovdiv, Bulgarien, 4000
    - UMHAT 'Sv. Georgi' EAD
  - Rousse, Bulgarien, 7000
    - Medical Center- Prolet Ltd
  - Rousse, Bulgarien, 7013
    - MC Rusemed ltd
  - Sevlievo, Bulgarien, 5402
    - Medical Center Unimed Eood
  - Sofia, Bulgarien, 1510
    - Medical Center Hera EOOD
  - Sofia, Bulgarien, 1309
    - Multiprofile Hospital For Active Treatment National Cardiology Hospital, Ead
  - Sofia, Bulgarien, 1407
    - Acibadem City Clinic Tokuda Hospital
  - Sofia, Bulgarien, 1750
    - University Multiprofile Hospital for Active Treatment- UMHAT Sveta Anna AD
  - Sofia, Bulgarien, 1680
    - DCC Convex EOOD
  - Sofia, Bulgarien, 1431
    - Diagnostic Consultation Centre 'Alexandrovska' EOOD
  - Sofia, Bulgarien, 1233
    - National Multiprofile Transport Hospital Tsar Boris III
  - Sofia, Bulgarien, 1527
    - University Multiprofile Hospital for Active Treatment - Tsaritsa Yoanna - ISUL, EAD
  - Sofia, Bulgarien, 1431
    - UMHAT Prof. Dr. Aleksandar Chirkov
  - Sofia, Bulgarien, 1000
    - Individual Ambulatory of Cardiology
  - Sofia, Bulgarien, 1202
    - DCC Ascendent EAD
  - Sofia, Bulgarien, 1202
    - Second Multiprofile Hospital for Active Treatment MHAT - Sofia AD
  - Sofia, Bulgarien, 1233
    - MHAT Knyaginya Klementina
  - Sofia, Bulgarien, 1612
    - Meditsinski Centar - Izgrev Eood
  - Sofia, Bulgarien, 1680
    - Medical Centre Kalimat
  - Sofia, Bulgarien, 1431
    - Diagnostic Consultation Centre Alexandrovska EOOD 1
  - Stara Zagora, Bulgarien, 6003
    - UMHAT Prof. Dr. St. Kirkovich AD
  - Stara Zagora, Bulgarien, 6010
    - Medical Center ZaraMed
  - Varna, Bulgarien, 9000
    - DCC Chaika EOOD
  - Veliko Tarnovo, Bulgarien, 5000
    - MHAT Dr Stefan Cherkezov
  - Veliko Tarnovo, Bulgarien, 5000
    - Medical Center -Medika Plus
  - Yambol, Bulgarien, 8600
    - MHAT Sv. Panteleymon AD
Canada
- Alberta
  - Calgery, Alberta, Canada, T2N 1N4
    - The Governers of the University of Calgary
  - Edmonton, Alberta, Canada, T6K 4C1
    - Alberta Health Services
- British Columbia
  - New Westminster, British Columbia, Canada, V3L 3W4
    - Fraser Clinical Trials Inc.
  - Surrey, British Columbia, Canada, V3V 0C6
    - Surrey Memorial Hospital
  - Victoria, British Columbia, Canada, V8R 4R2
    - Victoria Cardiac Arrhythmia Trials Inc
- Nova Scotia
  - Halifax, Nova Scotia, Canada, B3H 1V7
    - Queen Elizabeth II Health Sciences Centre
- Ontario
  - Brampton, Ontario, Canada, L6Z 4N5
    - Brampton Research Assoc
  - Cambridge, Ontario, Canada, N1R 7R1
    - Dr. Saul Vizel Cardiac Research Office
  - Mississauga, Ontario, Canada, L4Y 1M3
    - One Heart Care
  - Oshawa, Ontario, Canada, L1J 2K1
    - Dr. James Cha
  - Peterborough, Ontario, Canada, K9J 0B2
    - Kawartha Cardiology Clinical Trials
  - Waterloo, Ontario, Canada, N2T 0C1
    - CPS Research
- Quebec
  - Greenfield Park, Quebec, Canada, J4V 2G8
    - ViaCar Recherche Clinique Inc
  - Montreal, Quebec, Canada, H3G 1A4
    - Montreal General Hospital
  - Montreal, Quebec, Canada, H2X 0C1
    - CHUM - Pavillon B
  - Québec, Quebec, Canada, 00
    - Montreal Heart Institute
Chile
- - Puerto Varas, Chile, 5551070
    - Quantum Research
  - Santiago, Chile, 7500710
    - BioMedica Research Group
  - Santiago, Chile, 8331143
    - CeCim - Centro de Estudios Clinicos e Investigacion Medica
  - Santiago, Chile, 7500000
    - Enroll Spa
  - Santiago, Chile, 7500739
    - SMOLAM
  - Santiago, Chile
    - Sociedad Medica Cardiologica El Llano
  - Santiago, Chile, 8330024
    - Centro de Investigacion Clinica Universidad Catolica de Chile CICUC
  - Temuco, Chile, 4781156
    - Centro de Investigacion Clinica del Sur
  - Temuco, Chile, 4813299
    - Centro de Estudios Cardiologicos y de Medicina Interna
  - Viña del Mar, Chile, 2520997
    - Centro de Estudios Clinicos V Region Ltda
Danmark
- - Aarhus, Danmark, 8200
    - Aarhus University Hospital
  - Copenhagen S, Danmark, 2300
    - Amager Hospital
  - Herlev, Danmark, 2730
    - Gentofte Herlev Hospital
  - Herning, Danmark, 7400
    - Herning Regional Hospital
  - Holbæk, Danmark, 4300
    - Holbæk Sygehus
  - Hvidovre, Danmark, 2650
    - Hvidovre Hospital
  - Køge, Danmark, 4600
    - Køge Sygehus Region Sjaelland
  - Slagelse, Danmark, 4200
    - Slagelse Sygehus
  - Svendborg, Danmark, 5700
    - Odense University Hospital
Det Forenede Kongerige
- - Bristol, Det Forenede Kongerige, BS1 3NU
    - Bristol Royal Infirmary
  - Clydebank, Det Forenede Kongerige, G81 4HX
    - Golden Jubilee National Hospital
  - Dorchester, Det Forenede Kongerige, DT1 2JY
    - Dorset County Hospital
  - Exeter, Det Forenede Kongerige, EX2 5DW
    - Royal Devon and Exeter Hospital(Wonford)
  - High Wycombe, Det Forenede Kongerige, HP11 2TT
    - Wycombe Hospital
  - Lincoln, Det Forenede Kongerige, LN2 5QY
    - Lincoln County Hospital
  - London, Det Forenede Kongerige, EC1A 7BE
    - Barts Hospital
  - Sheffield, Det Forenede Kongerige, S5 7AU
    - Northern General Hospital
  - Stevenage, Det Forenede Kongerige, SG1 4AB
    - Lister Hospital
  - Truro, Det Forenede Kongerige, TR1 3LJ
    - Royal Cornwall Hospital
  - Wigan, Det Forenede Kongerige, WN1 2NN
    - Wrightington Hospital,Wrightington, Wigan and Leigh NHS Trus
  - Worcester, Det Forenede Kongerige, WR5 1DD
    - Worcestershire Royal Hospital
Estland
- - Tallinn, Estland, 13419
    - Dr. Arvo Rosenthal LLC
Filippinerne
- - Cavite, Filippinerne, 4118
    - Silang Specialists Medical Center
  - Cebu City, Filippinerne, 6000
    - Perpetual Succour Hospital
  - Davao City, Filippinerne, 8000
    - Davao Doctors Hospital
  - Davao City, Filippinerne, 8000
    - Central Lab Diabetes Wellness, Heart and Kidneys, Inc
  - Iloilo City, Filippinerne, 5000
    - St.Paul's Hospital-Iloilo
  - Lipa City, Filippinerne, 4217
    - Mary Mediatrix Medical Center
  - Manila, Filippinerne, 1634
    - St. Luke's Medical Center
  - San Fernando City, Filippinerne, 2000
    - GreenCity Medical Center
  - San Juan City, Filippinerne, 1502
    - Cardinal Santos Medical Center
Forenede Stater
- Alabama
  - Alexander City, Alabama, Forenede Stater, 35010
    - Advanced Cardiovascular, LLC
  - Birmingham, Alabama, Forenede Stater, 35205
    - Ascension St. Vincent's Health System
  - Dothan, Alabama, Forenede Stater, 36303
    - SEC Clinical Research
  - Huntsville, Alabama, Forenede Stater, 35801
    - HH Heart Center and Heart Center
  - Mobile, Alabama, Forenede Stater, 36608
    - CB Flock Research Corporation
- Arizona
  - Gilbert, Arizona, Forenede Stater, 85297
    - Mercy Gilbert Medical Center
  - Phoenix, Arizona, Forenede Stater, 85016
    - Arizona Heart Hospital
  - Phoenix, Arizona, Forenede Stater, 85008
    - Valleywise Health Medical Center
  - Phoenix, Arizona, Forenede Stater, 85016
    - Arizona Arrhythmia Research Center
  - Scottsdale, Arizona, Forenede Stater, 85251
    - HonorHealth Neurology
  - Scottsdale, Arizona, Forenede Stater, 85251
    - HonorHealth Neurology 1
- Arkansas
  - Little Rock, Arkansas, Forenede Stater, 72211
    - Arkansas Heart Hospital
- California
  - Bakersfield, California, Forenede Stater, 93301
    - Bakersfield Memorial Hospital
  - Beverly Hills, California, Forenede Stater, 90211
    - Vitality Clinical Research
  - Chula Vista, California, Forenede Stater, 91911
    - Sharp Chula Vista Medical Center
  - Chula Vista, California, Forenede Stater, 91910
    - Chula Vista Cardiac Clinic
  - Fremont, California, Forenede Stater, 94538
    - Mission Cardiovascular Research Institute
  - Glendora, California, Forenede Stater, 91741
    - Paradise Clinical Research Group LLC
  - Long Beach, California, Forenede Stater, 90806
    - Miller Children's at Long Beach Medical Center
  - Los Angeles, California, Forenede Stater, 90033
    - University of Southern California
  - Los Angeles, California, Forenede Stater, 90017
    - Los Angeles Cardiology Associates
  - Merced, California, Forenede Stater, 95340
    - Merced Vein and Vascular Center
  - Newport Beach, California, Forenede Stater, 92663
    - Radin Cardiovascular Medical Group
  - Northridge, California, Forenede Stater, 91325
    - Valley Clinical Trials, Inc.
  - Northridge, California, Forenede Stater, 91324
    - California Medical Research Associates, Inc.
  - Palm Springs, California, Forenede Stater, 92262
    - Desert Oasis Health Care
  - Pasadena, California, Forenede Stater, 91105
    - Havana Research Institute LLC
  - Rancho Mirage, California, Forenede Stater, 92270
    - Eisenhower Desert Cardiology Center
  - Redwood City, California, Forenede Stater, 94063
    - Stanford Health Care
  - San Diego, California, Forenede Stater, 92123
    - San Diego Cardiac Center
  - Santa Ana, California, Forenede Stater, 92705
    - Syrentis Clinical Research
  - Stockton, California, Forenede Stater, 95204
    - Ramin Manshadi, MD
  - Torrance, California, Forenede Stater, 90502
    - UCLA School of Medicine
  - Ventura, California, Forenede Stater, 93003
    - Cardiology Associates Medical Group
  - Vista, California, Forenede Stater, 92083
    - North County Internal Medicine
  - Walnut Creek, California, Forenede Stater, 94598
    - John Muir Physician Network Clin. Research Center
- Colorado
  - Aurora, Colorado, Forenede Stater, 80012
    - Aurora Denver Cardiology Associates
  - Denver, Colorado, Forenede Stater, 80218
    - Aurora Denver Cardiology Associates 1
  - Wheat Ridge, Colorado, Forenede Stater, 80033
    - Paradigm Clinical Research Centers, Inc.
- Connecticut
  - Bridgeport, Connecticut, Forenede Stater, 06610
    - Bridgeport Hospital
  - Danbury, Connecticut, Forenede Stater, 06810
    - Western Connecticut Health Network/Danbury Hospital
  - Stamford, Connecticut, Forenede Stater, 06905
    - Cardiology Associates of Fairfield County
  - Trumbull, Connecticut, Forenede Stater, 06611
    - PriMed Physicians, A Member of NE Medical Group
- Delaware
  - Newark, Delaware, Forenede Stater, 19713
    - Cardiology Physicians
- District of Columbia
  - Washington D.C., District of Columbia, Forenede Stater, 20037
    - George Washington University School of Medicine
- Florida
  - Altamonte Springs, Florida, Forenede Stater, 32714
    - Orlando Heart Specialists
  - Brandon, Florida, Forenede Stater, 33511
    - Bay Area Cardiology Associates, P.A. - Brandon Office
  - Clearwater, Florida, Forenede Stater, 33756
    - Clearwater Cardiovascular Consultants
  - Daytona Beach, Florida, Forenede Stater, 32117
    - Cardiology Associates Research Company
  - Daytona Beach, Florida, Forenede Stater, 32114
    - Cardiology Consultants
  - DeLand, Florida, Forenede Stater, 32720
    - Accel Research Sites
  - Gainesville, Florida, Forenede Stater, 32605
    - The Cardiac & Vascular Institute Research Foundation
  - Gainesville, Florida, Forenede Stater, 32610-0226
    - University of Florida College of Medicine
  - Jacksonville, Florida, Forenede Stater, 32216
    - East Coast Institute for Research
  - Lakeland, Florida, Forenede Stater, 33805
    - Watson Clinic
  - Largo, Florida, Forenede Stater, 33777
    - Clearwater Cardiovascular Consultants 1
  - Miami, Florida, Forenede Stater, 33155
    - Miami Clinical Research
  - Miami, Florida, Forenede Stater, 33173
    - Suncoast Research Associates, LLC
  - Miami, Florida, Forenede Stater, 33165
    - Reliant Medical Research
  - Miramar Beach, Florida, Forenede Stater, 32550
    - Ascension Sacred Heart Hospital
  - New Port Richey, Florida, Forenede Stater, 34652
    - Suncoast Clinical Research
  - Orange City, Florida, Forenede Stater, 32763-9116
    - Central Florida Medical Associates
  - Palm Beach Gardens, Florida, Forenede Stater, 33410
    - Cardiology Partners Clinical Research Institute
  - Pensacola, Florida, Forenede Stater, 32501
    - Cardiology Consultants 1
  - Pompano Beach, Florida, Forenede Stater, 33064
    - North Broward Hospital District
  - Port Charlotte, Florida, Forenede Stater, 33952
    - Charlotte Heart Group Research Center
  - Safety Harbor, Florida, Forenede Stater, 34695
    - Coastal Cardiology Consultants
  - Sarasota, Florida, Forenede Stater, 34239-3513
    - Cardiovascular Center of Sarasota
  - St. Petersburg, Florida, Forenede Stater, 33705
    - Heart and Vascular Institute of Florida
  - Tampa, Florida, Forenede Stater, 33606
    - University of South Florida
  - Tampa, Florida, Forenede Stater, 33613
    - Florida Hospital Tampa
  - Tampa, Florida, Forenede Stater, 33607
    - Adtremed Inc
  - Tampa, Florida, Forenede Stater, 33634
    - Helping Hands Health Center dba Helping Hands Evolution Research
  - Wellington, Florida, Forenede Stater, 33449
    - Cardiology Partners Clinical Research Institute 1
- Georgia
  - Atlanta, Georgia, Forenede Stater, 30303
    - Grady Memorial Hospital
  - Atlanta, Georgia, Forenede Stater, 30309
    - Piedmont Heart Institute
  - Atlanta, Georgia, Forenede Stater, 30309
    - Piedmont Heart Institute 1
  - Augusta, Georgia, Forenede Stater, 30912
    - Augusta University
  - Columbus, Georgia, Forenede Stater, 31904
    - Columbus Regional Research Institute
  - Cumming, Georgia, Forenede Stater, 30041
    - Atlanta Heart Specialists
  - Gainesville, Georgia, Forenede Stater, 30501
    - Northeast Georgia Heart Center
  - Thomasville, Georgia, Forenede Stater, 31792
    - Cardiology Consultants of South Georgia Inc
- Hawaii
  - Honolulu, Hawaii, Forenede Stater, 96813
    - The Queens Medical Center
- Idaho
  - Coeur d'Alene, Idaho, Forenede Stater, 83814
    - Kootenai Medical Center
- Illinois
  - Chicago, Illinois, Forenede Stater, 60611
    - Northwestern University
  - Chicago, Illinois, Forenede Stater, 60612
    - Rush University Medical Center
  - Gurnee, Illinois, Forenede Stater, 60031
    - Clinical Investigation Specialists
  - Hazel Crest, Illinois, Forenede Stater, 60429
    - Chicago Medical Research, LLC
  - Naperville, Illinois, Forenede Stater, 60540
    - Midwest Cardiovascular Institute
  - O'Fallon, Illinois, Forenede Stater, 62269
    - Prairie Education And Research Cooperative
  - Oak Lawn, Illinois, Forenede Stater, 60453
    - Advocate Heart Institute
  - Peoria, Illinois, Forenede Stater, 61636
    - Methodist Medical Center of Illinois
  - Quincy, Illinois, Forenede Stater, 62301
    - Blessing Hospital
  - Rockford, Illinois, Forenede Stater, 61107-5059
    - OSF HealthCare Cardiovascular Institute
  - Springfield, Illinois, Forenede Stater, 62702
    - Springfield Clinic 1st
- Indiana
  - Bloomington, Indiana, Forenede Stater, 47402
    - Bloomington Hospital
  - Indianapolis, Indiana, Forenede Stater, 46260
    - St. Vincent Medical Group, Inc.
  - Muncie, Indiana, Forenede Stater, 47303
    - IU Health Ball Memorial Hospital
- Kansas
  - Kansas City, Kansas, Forenede Stater, 66160
    - University of Kansas Medical Center
- Kentucky
  - Crittenden, Kentucky, Forenede Stater, 41030
    - St. Elizabeth Physicians
  - Louisville, Kentucky, Forenede Stater, 40202
    - Kentuckyone Health Neurology Associates
  - Owensboro, Kentucky, Forenede Stater, 42303
    - Owensboro Medical Practice
- Louisiana
  - Alexandria, Louisiana, Forenede Stater, 71301
    - Cambridge Medical Trials
  - Bossier City, Louisiana, Forenede Stater, 71111
    - Grace Research, LLC - Bossier City
  - Chalmette, Louisiana, Forenede Stater, 70043
    - Medical Research Specialists
  - Houma, Louisiana, Forenede Stater, 70360
    - Cardiovascular Institute of the South
  - New Orleans, Louisiana, Forenede Stater, 70112
    - Tulane University School of Medicine
  - New Orleans, Louisiana, Forenede Stater, 70121
    - Ochsner Health System
  - Shreveport, Louisiana, Forenede Stater, 71103
    - Louisiana State University Health Sciences Center
  - Shreveport, Louisiana, Forenede Stater, 71115
    - Pierremont Cardiology
  - West Monroe, Louisiana, Forenede Stater, 71291
    - Clinical Trials of America 1
- Maryland
  - Annapolis, Maryland, Forenede Stater, 21401
    - Luminis Health Anne Arundel Medical Center
  - Bethesda, Maryland, Forenede Stater, 20814
    - Suburban Hospital
  - Columbia, Maryland, Forenede Stater, 21044
    - Johns Hopkins University
  - Rockville, Maryland, Forenede Stater, 20850
    - Shady Grove Office
  - Salisbury, Maryland, Forenede Stater, 21804
    - Tidal Health Peninsula Regional Inc.
  - Towson, Maryland, Forenede Stater, 21204
    - Spectrum Clinical Research, Inc.
- Michigan
  - Ann Arbor, Michigan, Forenede Stater, 48109
    - University of Michigan
  - Flint, Michigan, Forenede Stater, 48503
    - Flint Clinical Research
  - Lansing, Michigan, Forenede Stater, 48912
    - Sparrow Clinical Research Institute
  - Petoskey, Michigan, Forenede Stater, 49770
    - Michigan Heart & Vascular Institute
  - Southgate, Michigan, Forenede Stater, 48195
    - Revival Research Institute LLC
  - Troy, Michigan, Forenede Stater, 48085
    - Oakland Medical Research
  - Ypsilanti, Michigan, Forenede Stater, 48197
    - Trinity Health Michigan d b a Michigan Heart
- Minnesota
  - Bloomington, Minnesota, Forenede Stater, 55426
    - HealthPartners Institute
  - Duluth, Minnesota, Forenede Stater, 55805
    - Essentia Health SMDC
  - Maplewood, Minnesota, Forenede Stater, 55109
    - Fairview Health System
- Mississippi
  - Jackson, Mississippi, Forenede Stater, 39202
    - Mississippi Baptist Health Systems
  - Olive Branch, Mississippi, Forenede Stater, 38654
    - Olive Branch Family Medical Center
  - Tupelo, Mississippi, Forenede Stater, 38801
    - Cardiology Associates of North Mississippi
- Missouri
  - Columbia, Missouri, Forenede Stater, 65211
    - The Curators of the University of Missouri on behalf of University of Missouri Health Care
  - St Louis, Missouri, Forenede Stater, 63110
    - Washington University School of Medicine
  - St Louis, Missouri, Forenede Stater, 63136
    - St. Louis Heart and Vascular
- New Jersey
  - Bridgewater, New Jersey, Forenede Stater, 08807
    - Advanced Heart Care, LLC
  - Haddon Heights, New Jersey, Forenede Stater, 08035
    - Cardiovascular Associates of the Delaware Valley
  - Marlton, New Jersey, Forenede Stater, 08053
    - Virtua Medical Group, PA
  - Ridgewood, New Jersey, Forenede Stater, 07450
    - The Valley Hospital
  - Teaneck, New Jersey, Forenede Stater, 07666
    - Holy Name Medical Center
- New York
  - Cortlandt Manor, New York, Forenede Stater, 10567
    - NYU Hudson Valley Cardiology
  - Jamaica, New York, Forenede Stater, 11418
    - Jamaica Hospital Medical Center
  - Kingston, New York, Forenede Stater, 12401
    - Westchester Medical Center Advanced Physician Services PC
  - Laurelton, New York, Forenede Stater, 11413
    - Laurelton Heart Specialist, PC
  - Middletown, New York, Forenede Stater, 10941
    - Crystal Run Healthcare LLP
  - Mineola, New York, Forenede Stater, 11501
    - NYU Langone Hospital Long Island
  - New York, New York, Forenede Stater, 10021
    - Weill Cornell Medical College
  - New York, New York, Forenede Stater, 10075
    - Lenox Hill Hospital
  - The Bronx, New York, Forenede Stater, 10469
    - Cardiac Care & Vascular Medicine, PLLC
- North Carolina
  - Asheville, North Carolina, Forenede Stater, 28803
    - Asheville Cardiology Associates
  - Greensboro, North Carolina, Forenede Stater, 27405
    - Guilford Neurologic Associates
  - Lenoir, North Carolina, Forenede Stater, 28645
    - Clinical Trials of America
  - Pinehurst, North Carolina, Forenede Stater, 28374
    - Pinehurst Medical Clinic Inc
  - Raleigh, North Carolina, Forenede Stater, 27607
    - Rex Hospital
  - Sanford, North Carolina, Forenede Stater, 27330
    - Sanford Cardiology
  - Wilmington, North Carolina, Forenede Stater, 28401
    - Wilmington Health Associates
- North Dakota
  - Minot, North Dakota, Forenede Stater, 58701
    - Trinity Medical Group
- Ohio
  - Akron, Ohio, Forenede Stater, 44304
    - Summa Health System
  - Cincinnati, Ohio, Forenede Stater, 45219
    - The Lindner Clinical Trial Center
  - Cleveland, Ohio, Forenede Stater, 44109
    - The MetroHealth System
  - Cleveland, Ohio, Forenede Stater, 44106
    - Louis Stokes Cleveland VA Med Ctr
  - Dayton, Ohio, Forenede Stater, 45414
    - Dayton Heart Center
  - Maumee, Ohio, Forenede Stater, 43537
    - Advanced Medical Research
  - Springfield, Ohio, Forenede Stater, 45505
    - The Heart House
  - Zanesville, Ohio, Forenede Stater, 43701
    - Genesis HealthCare System
- Oklahoma
  - Bartlesville, Oklahoma, Forenede Stater, 74006
    - Ascension Medical Group - St. John Clinic Infectious Disease
  - Oklahoma City, Oklahoma, Forenede Stater, 73104
    - University of Oklahoma Health Sciences Center
  - Oklahoma City, Oklahoma, Forenede Stater, 73120
    - Oklahoma Heart Hospital
  - Oklahoma City, Oklahoma, Forenede Stater, 73135
    - South Oklahoma Heart Research
  - Tulsa, Oklahoma, Forenede Stater, 74104
    - St John Health System Inc
- Oregon
  - Portland, Oregon, Forenede Stater, 97225
    - Providence Heart Clinic
- Pennsylvania
  - Chambersburg, Pennsylvania, Forenede Stater, 17201
    - Chambersburg Hospital
  - Erie, Pennsylvania, Forenede Stater, 16507
    - Hamot Medical Center
  - Newport, Pennsylvania, Forenede Stater, 17074
    - Capital Area Research
  - Philadelphia, Pennsylvania, Forenede Stater, 19104
    - Penn Presbyterian Medical Center
  - Pittsburgh, Pennsylvania, Forenede Stater, 15240
    - VA Pittsburgh Healthcare System
  - Pittsburgh, Pennsylvania, Forenede Stater, 15213
    - Hudson Valley Cardiovascular Practice, PC
  - Sayre, Pennsylvania, Forenede Stater, 18840
    - Donald Guthrie Foundation
  - Scranton, Pennsylvania, Forenede Stater, 18510
    - Geisinger Medical Center
  - Yardley, Pennsylvania, Forenede Stater, 19067
    - Cardiology Consultants of Philadelphia
  - York, Pennsylvania, Forenede Stater, 17403-3676
    - York Hospital
- South Carolina
  - Anderson, South Carolina, Forenede Stater, 29621
    - AnMed Health
  - Anderson, South Carolina, Forenede Stater, 29621
    - Internal Medicine Associates of Anderson
  - Columbia, South Carolina, Forenede Stater, 29204
    - MUSC Health Heart Vascular Columbia Medical Park DT III
  - Greenville, South Carolina, Forenede Stater, 29607
    - St. Francis Physician Services, Inc, DBA Upstate Cardiology Research
- South Dakota
  - Rapid City, South Dakota, Forenede Stater, 57701
    - Black Hills Cardiovascular Research
- Tennessee
  - Jackson, Tennessee, Forenede Stater, 38301
    - Jackson Madison County General Hospital
  - Jackson, Tennessee, Forenede Stater, 38301
    - Jackson Clinic
  - Johnson, Tennessee, Forenede Stater, 37604
    - Wellmont CVA Heart Institute
  - Kingsport, Tennessee, Forenede Stater, 37660
    - Holston Medical Group
  - Knoxville, Tennessee, Forenede Stater, 37923-4310
    - East Tennessee Heart Consultants
  - Nashville, Tennessee, Forenede Stater, 37205
    - Saint Thomas Health
  - Powell, Tennessee, Forenede Stater, 37849
    - Cardiovascular Associates
- Texas
  - Amarillo, Texas, Forenede Stater, 79109
    - PharmaTex Research
  - Amarillo, Texas, Forenede Stater, 79124
    - Amarillo Heart Clinical Research Institute
  - Austin, Texas, Forenede Stater, 78705
    - Ascension Texas Cardiovascular
  - Dallas, Texas, Forenede Stater, 75231
    - Texas Health Dallas
  - Dallas, Texas, Forenede Stater, 75204
    - Baylor Research Institute
  - Fort Worth, Texas, Forenede Stater, 76104
    - Plaza Medical Center of Fort Worth
  - Houston, Texas, Forenede Stater, 77030
    - Baylor College of Medicine
  - Houston, Texas, Forenede Stater, 77024
    - PrimeCare Medical Group
  - Houston, Texas, Forenede Stater, 77002
    - East Texas Cardiology, PA
  - Houston, Texas, Forenede Stater, 77077
    - Novel Research LLC
  - Katy, Texas, Forenede Stater, 77493
    - West Houston Area Clinical Trial Consultants LLC
  - Kingwood, Texas, Forenede Stater, 77339
    - Texas Cardiology Research Center
  - Odessa, Texas, Forenede Stater, 79761
    - Odessa Heart Institute
  - San Antonio, Texas, Forenede Stater, 78215
    - Sun Research Institute
  - Sugar Land, Texas, Forenede Stater, 77479
    - Southwest Medical Clinic
  - Tomball, Texas, Forenede Stater, 77375
    - Northwest Houston Clinical Research
  - Waco, Texas, Forenede Stater, 76712
    - Baylor Scott and White Research Institute
- Utah
  - Clinton, Utah, Forenede Stater, 84015
    - Alpine Research Organization
- Virginia
  - Burke, Virginia, Forenede Stater, 22015
    - Burke Internal Medicine and Research
  - Roanoke, Virginia, Forenede Stater, 24014
    - Roanoke Heart Institute PLC
- Washington
  - Everett, Washington, Forenede Stater, 98201
    - Providence Regional Medical Center Everett
  - Seattle, Washington, Forenede Stater, 98122
    - Swedish Medical Center
  - Tacoma, Washington, Forenede Stater, 98405
    - Universal Research Group, LLC
- Wisconsin
  - Wausau, Wisconsin, Forenede Stater, 54401
    - Wausau Hospital
  - Wauwatosa, Wisconsin, Forenede Stater, 53226
    - Allegiance Reserach Specialists, LLC
Frankrig
- - Angers, Frankrig, 49933
    - Chu Angers - Hôpital Hôtel Dieu
  - Bayonne, Frankrig, 64109
    - Centre Hospitalier de la Cote Basque
  - Brest, Frankrig, 29200
    - CHU de Brest - Hôpital de la Cavale Blanche
  - Bron, Frankrig, 69677
    - GH est - Hôpital Cardiovasculaire et Pneumologie Louis Pradel
  - Béziers, Frankrig, 34525
    - Centre Hospitalier de Beziers
  - Corbeil-Essonnes, Frankrig, 91106
    - Centre Hospitalier Sud Francilien
  - Créteil, Frankrig, 94010
    - Hôpital Henri Mondor
  - Dijon, Frankrig, 21033
    - CHU Dijon
  - Le Chesnay, Frankrig, 78157
    - Hôpital André Mignot
  - Limoges, Frankrig, 87000
    - CHU de Limoges Hopital Dupuytren
  - Marseille, Frankrig, 13385
    - CHU de la Timone
  - Montauban, Frankrig, 82000
    - Clinique Du Pont De Chaume
  - Nice, Frankrig, 06002
    - Centre Hospitalier Universitaire - de Nice - Hopital Pasteur
  - Paris, Frankrig, 75018
    - Hôpital Bichat - Claude Bernard
  - Paris, Frankrig, 75014
    - Hôpital Saint Joseph
  - Paris, Frankrig, 75010
    - Hôpital Lariboisière
  - Paris, Frankrig, 75679
    - Hôpital Cochin
  - Paris, Frankrig, 75013
    - Hopital BROCA
  - Paris, Frankrig, 75571
    - Hôpital Saint-Antoine
  - Pau, Frankrig, 64000
    - Centre Hospitalier de Pau
  - Pessac, Frankrig, 33604
    - Groupe Hospitalier Sud - Hôpital Xavier Arnozan
  - Poitiers, Frankrig, 86000
    - CHU Poitiers - Hôpital la Milétrie
  - Rouen, Frankrig, 78000
    - Clinique Saint-Hilaire - Centre Frédéric Joliot
  - Rouen, Frankrig, 76031
    - CHU Rouen Hopital Charles Nicolle
  - Valenciennes, Frankrig, 59300
    - Polyclinique Vauban
Grækenland
- - Alexandroupoli, Grækenland, 68100
    - Uni General Hospital of Alexandroupolis
  - Athens, Grækenland, 11527
    - Hippokration Hospital
  - Athens, Grækenland, 14233
    - General Hospital of Nea Ionia 'Konstantopoulio'
  - Athens, Grækenland, 115 27
    - General Hospital of Athens G Gennimatas
  - Kallithea, Grækenland, 17674
    - Onasseio Cardiosurgery Hospital
  - Pátrai, Grækenland, 26500
    - Patras University Hospital
  - Thessaloniki, Grækenland, 56429
    - Papageorgiou General Hospital
  - Thessaloniki, Grækenland, 57010
    - Papanikolaou General Hospital of Thessaloniki
  - Thessaloniki, Grækenland, 56429
    - Papageorgiou General Hospital 1
Holland
- - 's-Hertogenbosch, Holland, 5223 GZ
    - Jeroen Bosch Ziekenhuis
  - Alkmaar, Holland, 1815 JD
    - Noordwest Ziekenhuisgroep
  - Almelo, Holland, 7609
    - ZGT Cardioresearch
  - Amersfoort, Holland, 3813 TZ
    - Meander Medisch Centrum
  - Amsterdam, Holland, 1081 HV
    - VUMC Amsterdam
  - Amsterdam, Holland, 1091 AC
    - Onze Lieve Vrouwe Gasthuis
  - Delft, Holland, 2625 AD
    - Reinier de Graaf Gasthuis
  - Deventer, Holland, 7416 SE
    - Deventer Ziekenhuis
  - Doetinchem, Holland
    - Slingeland Ziekenhuis
  - Ede, Holland, 6716 RP
    - Ziekenhuis Gelderse Vallei
  - Eindhoven, Holland, 5623 EJ
    - Catharina Ziekenhuis
  - Gouda, Holland, 2800 BB
    - Groene Hart ziekenhuis
  - Heerlen, Holland, 6419 PC
    - Atrium Med.Centrum Heerlen - Afd.Interne - INT
  - Helmond, Holland, 5707 HA
    - Elkerliek Ziekenhuis
  - Leiderdorp, Holland, 2353 GA
    - Alrijne Ziekenhuis Leiden ; Cardiology
  - Nieuwegein, Holland, 3435 CM
    - St. Antonius Ziekenhuis Nieuwegein
  - Nijmegen, Holland, 6525GA
    - Radboudumc
  - Rotterdam, Holland, 3083 AN
    - Ikazia Ziekenhuis
  - Rotterdam, Holland, 3045 PM
    - Sint Franciscus Gasthuis
  - Sneek, Holland, 8601 ZR
    - D & A Research
  - Tilburg, Holland, 5022 GC
    - ETZ Elisabeth
  - Veldhoven, Holland, 5504 DB
    - Máxima Medisch Centrum
  - Zutphen, Holland, 7207 AE
    - Gelre Ziekenhuizen Zutphen
Indien
- - Aligarh, Indien, 202001
    - Jawaharlal Nehru Medical College and Hospital
  - Amritsar, Indien, 143004
    - Fortis Escorts Heart Institute and Research Centre
  - Aurangabad, Indien, 431005
    - Kamal Nayan Bajaj Hospital
  - Bangalore, Indien, 560034
    - St. John's National Academy of Health Sciences - St. John's Medical College Hospital
  - Bangalore, Indien, 560069
    - Sri Jayadeva Institute
  - Belagavi, Indien, 590010
    - KLE's Dr. Prabhakar Kore Hospital & Medical Research Centre (MRC)
  - Bengaluru, Indien, 560002
    - Bangalore Medical College and Research Institute
  - Bikaner, Indien, 334003
    - S.P.Medical College & AG of Hospitals
  - Chennai, Indien, 600002
    - Tamil Nadu Government Multi Super Speciality Hospital
  - Jaipur, Indien, 302020
    - Eternal Heart Care Centre
  - Jaipur, Indien, 302006
    - S. R. Kalla Memorial General Hospital
  - Karamsad, Indien, 388325
    - B M Patel Cardiac Centre
  - Kochi, Indien, 682018
    - Lisie Hospital
  - Kolkata, Indien, 700020
    - IPGMER and SSKM Hospital
  - Kolkata, Indien, 700014
    - NRS Medical College
  - Lucknow, Indien, 226014
    - Sanjay Gandhi Postgraduate Institute of Medical Sciences
  - Nagar, Indien, 440015
    - Swasthyam Superspeciality Hospital
  - Nagpur, Indien, 440010
    - Arneja Heart Institute
  - Nagpur, Indien, 440015
    - Central India Cardiology Hospital and Research Institute
  - Nashik, Indien, 422005
    - Chopda Medicare And Research Centre Pvt Ltd Magnum Heart Institute
  - New Delhi, Indien, 110029
    - All India Institute of Medical Sciences
  - New Delhi, Indien, 110060
    - Clinical Research Room
  - Patna, Indien, 800014
    - Indira Gandhi Institute of Medical Sciences
  - Pune, Indien, 411011
    - KEM Hospital & Research Centre
  - Secunderabad, Indien, 500003
    - Yashoda Super Speciality Hospitals
  - Shivamogga, Indien, 577201
    - Nanjappa Hospital
  - Vijayawada, Indien, 520008
    - Government Siddhartha Medical College
  - Visakhapatnam, Indien, 530002
    - King George Hospital
Israel
- - Afula, Israel, 18101
    - Haemek Medical Center
  - Hadera, Israel, 3810101
    - Hillel Yaffe Medical Center
  - Haifa, Israel, 31048
    - Bnai Zion Medical Center
  - Haifa, Israel, 3436212
    - Carmel Medical Center
  - Holon, Israel, 58100
    - Wolfson Medical Center
  - Jerusalem, Israel, 9124001
    - Hadassah Medical Center
  - Jerusalem, Israel, 22100
    - Hadassah University Hospita Ein Kerem
  - Kfar Saba, Israel, 4428164
    - Meir Medical Center
  - Nazareth, Israel, 16100
    - Holy Family Hospital
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center
  - Ramat Gan, Israel, 5262001
    - Chaim Sheba Medical Center
  - Rehovot, Israel, 7610001
    - Kaplan Medical Center
  - Rishon LeZiyyon, Israel, 70300
    - Assaf Harofeh Medical Center
  - Safed, Israel, 13100
    - Ziv Medical Center
Italien
- - Arezzo, Italien, 52100
    - Ospedale San Donato - ASL 8 Arezzo
  - Aversa, Italien, 81031
    - ASL Caserta_Presidio Ospedaliero San Giuseppe e Melorio_U.O.C. di Cardiologia
  - Bergamo, Italien, 24127
    - Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII)
  - Bergamo, Italien, 24125
    - Cliniche Humanitas Gavazzeni
  - Bologna, Italien, 40138
    - Azienda Opedaliero-Universitaria Policlinico Sant'orsola Malpighi di Bologna
  - Caserta, Italien, 81100
    - AORN Sant'anna e San Sebastiano
  - Catania, Italien, 95124
    - P.O. Vittorio Emanuele Azienda Ospedaliero Universitaria 'Policlinico Vittorio Emanuele'
  - Catanzaro, Italien, 88100
    - AO di Catanzaro Pugliese Ciaccio
  - Ferrara, Italien, 44124
    - Arcispedale S. Anna Ferrara
  - Lecco, Italien, 23900
    - Ospedale Manzoni
  - Massa, Italien, 54100
    - Fondazione Toscana Gabriele Monasterio CNR
  - Milan, Italien, 20122
    - Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
  - Milan, Italien, 20162
    - A O Ospedale Niguarda Ca Granda
  - Modena, Italien, 41124
    - AOU Policlinico di Modena
  - Monza, Italien, 20052
    - Azienda Socio Sanitaria Territoriale di Monza Presidio San Gerardo
  - Pavia, Italien, 27100
    - Fondazione IRCCS Policlinico San Matteo
  - Perugia, Italien, 06156
    - Aou Santa Maria Della Misericordia Di Udine
  - Pisa, Italien, 56126
    - A. O.U. Pisana Ospedale di Cisanello
  - Roma, Italien, 00152
    - A.O. San Camillo Forlanini
  - Roma, Italien, 00161
    - AOU Policlinico Umberto I
  - Roma, Italien, 00157
    - Ospedale Sandro Pertini di Roma Reparto Emodinamica
  - Roma, Italien, 00168
    - Fondazione Policlinico Universitario A Gemelli IRCCS
  - Rozzano, Italien, 20089
    - Istituto Clinico Humanitas
  - Sassari, Italien, 07100
    - P.O. Ss. Annunziata
  - Torino, Italien, 10126
    - Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino
  - Torrette Di Ancona, Italien, 60126
    - Azienda Ospedaliero Universitaria Ospedali Riuniti
Japan
- - Aichi, Japan, 486-8510
    - Kasugai Municipal Hospital
  - Bunkyō City, Japan, 113 8519
    - Tokyo Medical and Dental University Hospital
  - Chiba, Japan, 260 8677
    - Chiba University Hospital
  - Chiba, Japan, 273 8588
    - Funabashi Municipal Medical Center
  - Chikushino-shi, Japan, 818-8516
    - Saiseikai Futsukaichi Hospital
  - Fukuoka, Japan, 810 8563
    - National Hospital Organization Kyushu Medical Center
  - Fukuoka, Japan, 805-0050
    - Steel Memorial Yawata Hospital
  - Fukuoka, Japan, 812 8582
    - Kyushu University Hospital
  - Fukuoka, Japan, 819-1104
    - Junshinkai Nakamura Cardiovascular Clinic
  - Funabashi-shi, Japan, 274-8503
    - Chiba Tokushukai Hospital
  - Gifu, Japan, 500-8717
    - Gifu Prefectural General Medical Center
  - Higashiibaraki-gun, Japan, 311-3193
    - National Hospital Organization Mito Medical Center
  - Hirosaki-shi, Japan, 036-8562
    - Hirosaki University Hospital
  - Hiroshima, Japan, 734-8530
    - Hiroshima Prefectural Hospital
  - Hiroshima, Japan, 734 8551
    - Hiroshima University Hospital
  - Hokkaido, Japan, 053-8567
    - Tomakomai City Hospital
  - Hyōgo, Japan, 660-8550
    - Hyogo Prefectural Amagasaki General Medical Center
  - Isehara, Japan, 259-1193
    - Tokai University Hospital
  - Ishikawa, Japan, 924-0865
    - Public Central Hospital of Matto Ishikawa
  - Ishikawa, Japan, 920 8650
    - National Hospital Organization Kanazawa Medical Center
  - Itabashi Ku, Japan, 173 8606
    - Teikyo University Hospital
  - Kagoshima, Japan, 892-0822
    - Central Clinic
  - Kasuga-shi, Japan, 816-0864
    - Fukuoka Tokushukai Hospital
  - Kawasaki-shi, Japan, 212-0021
    - Sekishinkai Second Kawasaki Saiwai Clinic
  - Kitakyushu-shi, Japan, 802-8555
    - Kokura Memorial Hospital
  - Kumamoto, Japan, 861-4193
    - Saiseikai Kumamoto Hospital
  - Kumamoto, Japan, 860-8556
    - Kumamoto University Hospital
  - Kusatsu-shi, Japan, 525-8585
    - Seikokai Omi Medical Center
  - Kyoto, Japan, 606-8507
    - Kyoto University Hospital
  - Matsuyama, Japan, 790-0024
    - Ehime Prefectural Central Hospital
  - Mito, Japan, 310-0055
    - Seijunkai Mito Hospital
  - Miyazaki, Japan, 880-2102
    - Miyazaki Medical Association Hospital
  - Miyazaki, Japan, 885-0002
    - Miyakonojo Medical Association Hospital
  - Nagoya, Japan, 466-8650
    - Japanese Red Cross Nagoya Daini Hospital
  - Narashino-shi, Japan, 275-8580
    - Saiseikai Narashino Hospital
  - Nishi-Tokyo-shi, Japan, 202-0012
    - Miwa Heart Clinic
  - Nishinomiya Shi, Japan, 663 8501
    - Hyogo Medical University Hospital
  - Okayama, Japan, 700-8558
    - Okayama University Hospital
  - Okinawa, Japan, 902-8511
    - Naha City Hospital
  - Osaka, Japan, 540-0006
    - National Hospital Organization Osaka National Hospital
  - Osaka, Japan, 565-0871
    - Osaka University Hospital
  - Osaka, Japan, 543-0035
    - Osaka Police Hospital
  - Osaka, Japan, 530-0001
    - Watanabeigakukai Sakurabashi Watanabe Hospital
  - Osaka Sayama Shi, Japan, 589 8511
    - Kindai University Hospital
  - Sagamihara, Japan, 252-0375
    - Kitasato University Hospital
  - Saitama-shi, Japan, 339-0033
    - Iwatsuki Minami Hospital
  - Sapporo, Japan, 003-0026
    - Matsuda Hospital
  - Sapporo, Japan, 064-8570
    - Sanseikai Miyanomori Memorial Hospital
  - Sendai, Japan, 980 8574
    - Tohoku University Hospital
  - Shinagawa City, Japan, 142 8666
    - Showa University Hospital
  - Shinjuku-ku, Japan, 162-8666
    - Tokyo Women's Medical University Hospital
  - Suita-Shi, Japan, 564-8565
    - National Cerebral and Cardiovascular Center
  - Takatsuki-shi, Japan, 569-1096
    - Japanese Red Cross Takatsuki Hospital
  - Tokyo, Japan, 160-0023
    - Tokyo Medical University Hospital
  - Tokyo, Japan, 192-0038
    - Kenshinkai Minamino Cardiovascular Hospital
  - Tokyo, Japan, 181 8611
    - Kyorin University Hospital
  - Tokyo, Japan, 113 8603
    - Nippon Medical School Hospital
  - Tokyo, Japan, 173 8610
    - Nihon University Itabashi Hospital
  - Tokyo, Japan, 106-0031
    - The Cardiovascular Institute Hospital
  - Tokyo, Japan, 198-0042
    - Ome Medical Center
  - Tomakomai, Japan, 053-8506
    - Oji General Hospital
  - Toyoake, Japan, 470-1192
    - Fujita Health University Hospital
  - Toyota-shi, Japan, 471-8513
    - Toyota Memorial Hospital
  - Uwajima-shi, Japan, 798-8510
    - Uwajima City Hospital
  - Yokohama, Japan, 222-0036
    - Yokohama Rosai Hospital
  - Yokohama, Japan, 232 0024
    - Yokohama City University Medical Center
  - Yufu, Japan, 879-5593
    - Oita University Hospital
Kina
- - Beijing, Kina, 100191
    - Peking University Third Hospital
  - Beijing, Kina, 100029
    - Beijing Anzhen Hospital, Capital Medical University
  - Beijing, Kina, 100039
    - Chinese PLA General Hospital
  - Cangzhou, Kina, 61000
    - Cangzhou People's Hospital
  - Changchun, Kina, 130021
    - The First Hospital of Jilin University
  - Changchun, Kina, 130021
    - Jilin Province Peoples Hospital
  - Changsha, Kina, 410013
    - The Third Xiangya Hospital of Central South University
  - Changsha, Kina, 410015
    - The Third Hospital of Changsha
  - Changzhou, Kina, 213004
    - Changzhou No 2 Peoples Hospital
  - Chengdu, Kina, 610041
    - West China Hospital Sichuan University
  - Chengdu, Kina, 610072
    - Sichuan Provincial Peoples Hospital
  - Chongqing, Kina, 400014
    - Chongqing General Hospital
  - Daqing, Kina, 163311
    - Heilongjiang Daqing People's Hospital
  - Dongguan, Kina, 523059
    - Dongguan People s Hospital
  - Fuzhou, Kina, 350005
    - The First Affiliated Hospital of Fujian Medical University
  - Ganzhou, Kina, 341000
    - Jiangxi Ganzhou Peoples Hospital
  - Guangzhou, Kina, 510080
    - Guangdong Provincial People's Hospital
  - Guangzhou, Kina, 510280
    - ZhuJiang Hospital of Southern Medical University
  - Guangzhou, Kina, 510080
    - The First Affiliated Hospital of Sun Yat-sen University
  - Guangzhou, Kina, 510630
    - The Third Affiliated Hospital Sun Yat sen University
  - Guiyang, Kina, 550000
    - The Affiliated Hospital of Guizhou Medical University
  - Guiyang, Kina, 550002
    - GuiZhou Privicial Peoples Hospital
  - Haikou, Kina, 570102
    - Affiliated Hospital of Hainan Medical University
  - Hangzhou, Kina, 310006
    - Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine
  - Hefei, Kina, 230601
    - The Second Hospital of Anhui Medical University
  - Hefei, Kina, 230001
    - Anhui Province Hospital
  - Hohhot, Kina, 010017
    - Inner Mongolia People's Hospital
  - Jieyang, Kina, 522091
    - Jieyang Peoples Hospital
  - Jinan, Kina, 250012
    - Qilu Hospital of Shandong University
  - Jining, Kina, 272011
    - Shandong Jining No.1 People's Hospital
  - Lanzhou, Kina, 730030
    - Lanzhou university second hospital
  - Luoyang, Kina, 471002
    - Luoyang Third People's Hospital
  - Nanchang, Kina, 330006
    - The Second Affiliated Hospital of Nanchang University
  - Nanchang, Kina, 330006
    - Jiangxi Provincial Peoples Hospital
  - Nanchang, Kina, 330009
    - Nanchang Peoples hospital
  - Ningbo, Kina, 315010
    - Ningbo First Hospital
  - Shanghai, Kina, 200032
    - Zhongshan Hospital Fudan University
  - Shanghai, Kina, 200011
    - Shanghai Ninth Peoples Hospital
  - Shanghai, Kina, 201508
    - Jinshan Hospital Fudan University
  - Shantou, Kina, 515041
    - The First Affiliated Hospital of Shantou University Medical
  - Shenyang, Kina, 110004
    - Shengjing Hospital of China Medical University
  - Shenzhen, Kina, 518052
    - Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen
  - Shijiazhuang, Kina, 050000
    - The Second Hospital of Hebei Medical University
  - Suzhou, Kina, 215006
    - The First Affiliated Hospital of Soochow University
  - Taian, Kina, 271000
    - Taian City Central Hospital
  - Taiyuan, Kina, 030013
    - Shanxi Cardiovascular Hospital
  - Taizhou, Kina, 318020
    - Taizhou First Peoples Hospital
  - Tianjin, Kina, 300052
    - Tianjin Medical University General Hospital
  - Tianjin, Kina, 300457
    - Teda International Cardiovascular Hospital
  - Tianjin, Kina, 300121
    - Tianjin People's Hospital
  - Tianjin, Kina, 300051
    - Tianjin Chest Hospital
  - Tianjin, Kina, 300140
    - Tianjin 4th Center Hospital
  - Tianjin, Kina, 300211
    - The 2nd Hospital of Tianjin Medical University
  - Wenzhou, Kina, 325000
    - The First Affiliated Hospital of Wenzhou Medical University
  - Wenzhou, Kina, 325000
    - Wenzhou Peoples Hospital
  - Wuhan, Kina, 430014
    - The Central Hospital of Wuhan
  - Wuhan, Kina, 430060
    - Union Hospital Tongji Medical College of Huazhong University of Science and Technology
  - Xi'an, Kina, 710068
    - Shaanxi Provincial Peoples Hospital
  - Xinxiang, Kina, 453003
    - The Third Affiliated Hospital of Xinxiang Medical University
  - Xuzhou, Kina
    - The Affiliated Hospital of Xuzhou Medical College
  - Yangzhou, Kina, 225001
    - Northern Jiangsu Peoples Hospital
  - Yantai, Kina, 264000
    - Yantai Yuhuangding Hospital
  - Yinchuan, Kina, 750004
    - General Hospital of Ningxia Medical Hospital
  - Zhanjiang, Kina, 524001
    - Affiliated Hospital of Guangdong Medical University
  - Zhengzhou, Kina, 450016
    - The 7th Peoples Hospital of Zhengzhou
  - Zunyi, Kina, 563099
    - Affiliated Hospital Of Zunyi Medical University
Kroatien
- - Dubrovnik, Kroatien, 20000
    - General Hospital Dubrovnik
  - Karlovac, Kroatien, 47000
    - Opća bolnica Karlovac
  - Krapinske Toplice, Kroatien, 49217
    - Special Hospital for medical rehabilitation
  - Krapinske Toplice, Kroatien, 49217
    - Clinic for Cardiovascular Disease Magdalena
  - Varaždin, Kroatien, 42000
    - OB Varazdin
  - Varaždin, Kroatien, 42000
    - OB Varazdin 1
  - Zadar, Kroatien, 23000
    - Zadar General Hospital
  - Zagreb, Kroatien, 10000
    - University Hospital Dubrava
  - Zagreb, Kroatien, 10000
    - Polyclinic Bonifarm
  - Zagreb, Kroatien, 10000
    - Poliklinika Solmed
  - Čakovec, Kroatien, 40000
    - Zupanijska bolnica Cakovec
Letland
- - Daugavpils, Letland, LV5417
    - Daugavpils Regional Hospital
  - Riga, Letland, LV-1002
    - Pauls Stradins Clinical University Hospital
  - Riga, Letland, LV-1038
    - Riga East Clinical University Hospital
Litauen
- - Kaunas, Litauen, 49449
    - Saules Seimos Medicinos Centras, JSC
  - Kaunas, Litauen, 49387
    - Klinikiniai sprendimai JSC
  - Kaunas, Litauen, LT-47144
    - Kaunas Clinical Hospital, Public Institution
  - Klaipėda, Litauen, LT-92288
    - Klaipeda Seamen's Hospital, Public Institution
  - Vilnius, Litauen, LT-08661
    - Vilnius University Hospital Santariskiu Clinic, Public Institution
  - Vilnius, Litauen, LT-08406
    - Inlita, JSC
  - Vilnius, Litauen, LT-08406
    - Inmedica, JSC
  - Vilnius, Litauen, 08661
    - Vilnius University Hospital Santariskiu Clinic, Public Institution 1
Malaysia
- - Alor Star, Malaysia, 05460
    - Hospital Sultanah Bahiyah
  - Kota Bharu, Malaysia, 15200
    - Hospital University Sains Malaysia
  - Kota Kinabalu, Malaysia, 88300
    - Queen Elizabeth II Hospital
  - Kuala Lumpur, Malaysia, 50400
    - Institut Jantung Negara
  - Kuantan, Malaysia, 25100
    - Hospital Tengku Ampuan Afzan
  - Selayang Baru Utara, Malaysia, 68000
    - Universiti Teknologi MARA
  - Seri Manjung, Malaysia, 32040
    - Hospital Seri Manjung
  - Taiping, Malaysia, 34000
    - Hospital Taiping
New Zealand
- - Auckland, New Zealand, 1030
    - Auckland City Hospital
  - Auckland, New Zealand, 0740
    - North Shore Hospital
  - Christchurch, New Zealand, 8140
    - University of Otago
  - Dunedin, New Zealand, 9016
    - Dunedin Public Hospital
  - Hamilton, New Zealand, 3200
    - Waikato Hospital
  - Hastings, New Zealand
    - Hawkes Bay Hospital
  - New Plymouth, New Zealand, 4342
    - Taranaki Base Hospital
  - Otahuhu, New Zealand, 2025
    - Middlemore Hospital
  - Rotorua, New Zealand, 3010
    - Rotorua Hospital
  - Tauranga, New Zealand, 3143
    - Tauranga Hospital
Polen
- - Biała Podlaska, Polen, 21 500
    - Wojewodzki Szpital Specjalistyczny
  - Bydgoszcz, Polen, 85-796
    - Centrum Medyczne Pratia Bydgoszcz
  - Bydgoszcz, Polen, 85 231
    - NZOZ Centrum Medyczne KERmed
  - Bydgoszcz, Polen, 85 048
    - IN VIVO Sp. z o.o
  - Bydgoszcz, Polen, 85 605
    - Centrum Medyczne Intercor Sp z o o
  - Chojnice, Polen, 89 600
    - Centrum Medyczne Pratia Chojnice
  - Chorzów, Polen, 41-500
    - DIAB SERWIS Popenda Sp. Jawna Specjalistyczna Przychodnia Lekarska
  - Chorzów, Polen, 41-500
    - M2M MED Badania Spolka z o. o
  - Chrzanów, Polen, 32-500
    - Centrum Medyczne MBB-MED
  - Elblag, Polen, 82-300
    - NZOZ Twoje Zdrowie El
  - Gdansk, Polen, 80-286
    - Poradnia Kardiologiczna Jaroslaw Jurowiecki
  - Gdynia, Polen, 81-157
    - Private Practice - Dr. Krzysztof Cymerman
  - Gdynia, Polen, 81-423
    - NZOZ Procordis Pawel Miekus
  - Grodzisk Mazowiecki, Polen, 05 825
    - MCBK Iwona Czajkowska Anna Podrazka Szczepaniak S C
  - Jelenia Góra, Polen, 58 506
    - Centrum Medyczne Pratia Jelenia Gora
  - Katowice, Polen, 40-555
    - Kardio Klinika Brynow
  - Katowice, Polen, 40-282
    - Silmedic sp. z o.o
  - Katowice, Polen, 40-156
    - Clinical Medical Research Sp. z o.o.
  - Katowice, Polen, 40 081
    - Centrum Medyczne Pratia Katowice
  - Katowice, Polen, 40-752
    - Niepubliczny Zaklad Opieki Zdrowotnej
  - Kielce, Polen, 25-525
    - Specjalistyczna Poradnia Kardiologiczna i Nadcisnienia Tetniczego
  - Krakow, Polen, 30-082
    - Ewa Mirek-Bryniarska Specjalistyczna Praktyka Lekarska
  - Krakow, Polen, 30-721
    - Centrum Medyczne Linden
  - Krakow, Polen, 31 216
    - Centrum Medyczne Zdrowa J Trebacz W Zajdel s j
  - Krakow, Polen, 31-501
    - Krakowskie Centrum Medyczne Sp z o o NZOZ
  - Krakow, Polen, 31-826
    - Odzial Kardiologii i Chorob Wewnetrznych Szpital Specjalistyczny im. Ludwika Rydygiera
  - Legnica, Polen, 59-220
    - B.Miklaszewicz&D.Dabrowski CARDIMED Spolka Jawna
  - Lodz, Polen, 94-255
    - Indywidualna Specjalistyczna Praktyka Lekarska
  - Lodz, Polen, 94-048
    - NZOZ ALL-MED Centrum Medyczne Specjalistyczne Gabinety Lekarskie
  - Lodz, Polen, 91 363
    - Centrum Medyczne AMED oddzial w Lodzi
  - Lodz, Polen, 93 338
    - Instytut Centrum Zdrowia Matki Polki
  - Lodz, Polen, 91 034
    - Centrum Medyczne Med Gastr
  - Lodz, Polen, 90 302
    - SANTA FAMILIA Centrum Badan Profilaktyki i Leczenia
  - Lowicz, Polen, 99 400
    - Lowickie Centrum Kardiologii
  - Lublin, Polen, 20 049
    - 1 Wojskowy Szpital Kliniczny Z Poliklinika SPZOZ W Lublinie
  - Lublin, Polen, 20 362
    - KO MED Centra Kliniczne LUBLIN
  - Lublin, Polen, 20 412
    - ETG Lublin
  - Olsztyn, Polen, 10-010
    - FutureMeds Olsztyn
  - Ostrowiec Świętokrzyski, Polen, 27-400
    - Ostrowieckie Centrum Medyczne Spólka Cywilna Anna Olech-Cudzik, Krzysztof Cudzik
  - Oświęcim, Polen, 32-600
    - Medicome Sp. z o.o.
  - Piaseczno, Polen, 05-500
    - Nzoz Heureka
  - Poznan, Polen, 60-693
    - Med-Polonia Sp. z o.o.
  - Poznan, Polen, 61 853
    - NZOZ NEURO KARD Ilkowski i Partnerzy Sp Partnerska Lekarzy
  - Przemyśl, Polen, 37-700
    - Wojewodzki Szpital im Sw Ojca Pio w Przemyslu
  - Ruda Śląska, Polen, 41-709
    - Janusz Spyra Specjalistyczna Praktyka Lekarska
  - Rzeszów, Polen, 35-055
    - Centrum Medyczne MEDYK
  - Siedlce, Polen, 08-110
    - ETG Siedlce
  - Siedlce, Polen, 08-110
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej w Siedlcach
  - Skierniewice, Polen, 96-100
    - Velocity Nova spolka z ograniczona odpowiedzialnoscia
  - Warsaw, Polen, 02-793
    - Etg Warszawa
  - Warsaw, Polen, 02 637
    - Narodowy Instytut Geriatrii Reumatologii i Rehabilitacji im prof dr hab med Eleonory Reicher
  - Warsaw, Polen, 00 2015
    - FutureMeds Warszawa Centrum
  - Warsaw, Polen, 03 291
    - FutureMeds Targówek
  - Wroclaw, Polen, 53-030
    - CM Sedimed Wroclaw
  - Wroclaw, Polen, 50 368
    - Uniwersytecki Szpital Kliniczny im Jana Mikulicza Radeckiego we Wroclawiu
  - Wroclaw, Polen, 50 981
    - 4 Wojskowy Szpital Kliniczny z Poliklinika SP ZOZ
  - Wroclaw, Polen, 51 314
    - NZOZ Zdrowie s c Agnieszka i Donald Drozdz
  - Zamość, Polen, 22-400
    - Velocity Zamosc
  - Zamość, Polen, 22 400
    - ETG Zamość
  - Żarów, Polen, 58-130
    - Centrum Medyczne Serafin med
Portugal
- - Coimbra, Portugal, 3000-075
    - Uls Coimbra - Hosp. Univ. Coimbra
  - Covilha, Portugal, 6200-074
    - Centro Hospitalar Cova da Beira, EPE - Hospital Pêro da Covilhã
  - Figueira da Foz Municipality, Portugal, 3094-001
    - Hospital Distrital Fig Da Foz Gala
  - Lisbon, Portugal, 1649-035
    - Centro Hospitalar de Lisboa Norte Hospital Santa Maria
  - Lisbon, Portugal, 2790-134
    - Centro Hospitalar Lisboa Ocidental - Hospital São Fracisco Xavier
  - Santa Maria da Feira, Portugal, 4520-211
    - Centro Hospitalar de Entre o Douro e Vouga, E.P.E
  - Torres Novas, Portugal, 2350-325
    - Largo da Igreja Velha Edifício CCA
  - Vila Nova de Gaia, Portugal, 4434-502
    - Centro Hospitalar de Vila Nova de Gaia Espinho E P E
  - Vila Real, Portugal, 5000-508
    - Centro Hospitalar de Trás os Montes e Alto Douro- Vila Real
Rumænien
- - Baia Mare, Rumænien, 430222
    - CMI Cardiologie Dr. Calin Pop
  - Brasov, Rumænien, 500283
    - Centrul Medical de Diagnostic si Tratament Ambulator NEOMED
  - Brasov, Rumænien, 500091
    - Centrul Medical Unirea SRL
  - Brăila, Rumænien, 810119
    - Spitalul Judetean de Urgenta Braila
  - Bucharest, Rumænien, 050659
    - Spitalul Clinic de Urologie Prof. Dr. Theodor Burghele
  - Bucharest, Rumænien, 022322
    - Institutul de urgenta pentru Boli Cardiovasculare Prof. Dr. C.C. Iliescu
  - Bucharest, Rumænien, 010192
    - Clinica Medicala Data Plus SRL
  - Bucharest, Rumænien, 011794
    - Centrul Medical de Diagnostic si Tratament Ambulatoriu si Medicina Preventiva
  - Bucharest, Rumænien, 014142
    - S C Delta Health Care S R L
  - Cluj-Napoca, Rumænien, 400000
    - Spitalul Angiocare SRL
  - Iași, Rumænien, 700503
    - Institutul de Boli Cardiovasculare Iasi
  - Iași, Rumænien, 700786
    - Cardiomed SRL
  - Oradea, Rumænien, 410169
    - Spitalul Clinic Judetean de Urgenta Oradea
  - Piteşti, Rumænien, 110424
    - SAL MED Pitesti
  - Sibiu, Rumænien, 550245
    - Spitalul Clinic Judetean Sibiu
  - Suceava, Rumænien, 720049
    - Cabinet Medical Cardiologie Cojocariu Titel Razvan
  - Tg. Mures, Rumænien, 540136
    - Spitalul Clinic Judetean de Urgenta Targu Mures
  - Timișoara, Rumænien, 300043
    - Clinica Medicaliss
  - Târgu Mureş, Rumænien, 540143
    - Cmi Dr Podoleanu Cristian
Serbien
- - Belgrade, Serbien, 11080
    - Clinical Center Bezanijska kosa
  - Belgrade, Serbien, 11000
    - University Clinical Center of Serbia
  - Belgrade, Serbien, 11080
    - University Clinical Hospital Center Dr Dragisa Misovic- Dedi
  - Belgrade, Serbien, 11000
    - Institute for Cardiovascular diseases Dedinje
  - Belgrade, Serbien, 11000
    - University Clinical Center of Serbia 1
  - Belgrade, Serbien, 11000
    - University Clinical Center of Serbia 2
  - Belgrade, Serbien, 11040
    - Institute for Cardiovascular diseases Dedinje 1
  - Belgrade, Serbien, 11040
    - Institute for Cardiovascular diseases Dedinje 2
  - Belgrade, Serbien, 11080
    - University Clinical Hospital Center Dr Dragisa Misovic- Dedi 1
  - Kamenitz, Serbien, 21204
    - Institute of Cardiovascular Diseases of Vojvodina
  - Kragujevac, Serbien, 34000
    - Clinical Center of Kragujevac
  - Niš, Serbien, 18000
    - Clinical Center Nis
  - Niška Banja, Serbien, 18205
    - Institute for Treatment and Rehabilitation Niska Banja
  - Pančevo, Serbien, 26000
    - General Hospital Pancevo
  - Smederevo, Serbien, 11300
    - General Hospital Smederevo
  - Sremska Mitrovica, Serbien, 22000
    - General Hospital Sremska Mitrovica
  - Užice, Serbien, 31000
    - General Hospital Uzice
  - Zaječar, Serbien, 19000
    - Health Center Zajecar
Singapore
- - Singapore, Singapore, 169856
    - Singapore General Hospital
  - Singapore, Singapore, 169609
    - National Heart Centre (NHC) Singapore
Slovakiet
- - Bardejov, Slovakiet, 08501
    - ALIAN s.r.o.
  - Bardejov, Slovakiet, 08501
    - Thyreomedical s r o
  - Bratislava, Slovakiet, 83348
    - Narodny ustav srdcovych a cievnych chorob
  - Bratislava, Slovakiet, 83101
    - Kardiovaskularne centrum, s.r.o.
  - Bratislava, Slovakiet, 81104
    - Cardioconsult s.r.o.
  - Bratislava, Slovakiet, 82101
    - Univerzitna nemocnica Bratislava
  - Bratislava, Slovakiet, 85101
    - Veria, s.r.o Kardiologicka ambulancia
  - Brezno, Slovakiet, 977 01
    - Nemocnica s poliklinikou Brezno
  - Dolný Kubín, Slovakiet, 02601
    - KARDIO-ONKOLOGIA s.r.o. Kardiologicka ambulancia
  - Košice, Slovakiet, 040 11
    - Východoslovenský Ústav Srdcových A Cievnych Chorôb, A.S.
  - Košice, Slovakiet, 04022
    - Cardio D&R, s.r.o.
  - Košice, Slovakiet, 4001
    - Kardiologicka ambulancia Medicalgroup s.r.o.
  - Lučenec, Slovakiet, 98401
    - IN-DIA s.r.o.
  - Lučenec, Slovakiet, 98401
    - KARDIO 1 s.r.o.
  - Lučenec, Slovakiet, 98401
    - Kardiomed, S.R.O.
  - Moldava nad Bodvou, Slovakiet, 4501
    - Kardiologicka ambulancia MEDI M&M s.r.o.
  - Nitra, Slovakiet, 95001
    - Fakultna nemocnica Nitra
  - Nové Zámky, Slovakiet, 94052
    - Cardioinvest s.r.o.
  - Prešov, Slovakiet, 08001
    - Medispol s.r.o Interna a kardiologicka ambulancia
  - Prešov, Slovakiet, 08081
    - Fakultna nemocnica s poliklinikou J.A. Reimana Presov
  - Svidník, Slovakiet, 08901
    - Interna SK s.r.o.
  - Žilina, Slovakiet, 01001
    - MEDIVASA s.r.o.
Spanien
- - A Coruña, Spanien, 15006
    - Hosp Univ A Coruna
  - Alicante, Spanien, 3540
    - Hosp. Gral. Univ. de Alicante
  - Barcelona, Spanien, 08041
    - Hosp. de La Santa Creu I Sant Pau
  - Barcelona, Spanien, 08003
    - Hosp. Del Mar
  - Barcelona, Spanien, 08907
    - Hosp. Univ. de Bellvitge
  - El Palmar, Spanien, 30120
    - Hosp. Univ. Virgen de La Arrixaca
  - Lleida, Spanien, 25198
    - Hosp. Univ. Arnau de Vilanova de Lleida
  - Madrid, Spanien, 28046
    - Hosp. Univ. La Paz
  - Madrid, Spanien, 28006
    - Hosp. Univ. de La Princesa
  - Madrid, Spanien, 28003
    - Hosp. Virgen de La Luz
  - Manises, Spanien, 46940
    - Hosp. de Manises
  - Málaga, Spanien, 29010
    - Hosp Virgen de La Victoria
  - Sabadell, Spanien, 08208
    - Corporacio Sanitari Parc Tauli
  - Santiago de Compostela, Spanien, 15706
    - Hosp. Clinico Univ. de Santiago
  - Valencia, Spanien, 46010
    - Hosp. Clinico Univ. de Valencia
  - Valencia, Spanien, 46014
    - Hosp. Clinico Univ. de Valencia 1
Sydafrika
- - Cape Town, Sydafrika, 7500
    - Tread Research
  - Centurion, Sydafrika, 0157
    - Johese Clinical Research
  - Johannesburg, Sydafrika, 2192
    - Garda, RA
  - Krugersdorp, Sydafrika, 1739
    - DJW Research
  - Pretoria, Sydafrika, 0002
    - Clinical Research Unit, University of Pretoria
  - Pretoria, Sydafrika, 0181
    - Into Research
  - Somerset West, Sydafrika, 7130
    - Dr J.M. Engelbrecht Trial Site
  - Somerset West, Sydafrika, 7130
    - Helderberg Research Institute
  - Tongaat, Sydafrika, 4399
    - Mediclinic Victoria Hospital
  - Worcester, Sydafrika, 6850
    - Clinical Projects Research SA (PTY) LTD
Sydkorea
- - Anyang-si, Sydkorea, 431-796
    - Hallym University Sacred Heart Hospital
  - Busan, Sydkorea, 49241
    - Pusan National University Hospital
  - Busan, Sydkorea, 47392
    - Inje university busan paik hospital
  - Busan, Sydkorea, 602 812
    - Dong-A University Hospital
  - Cheonan-si, Sydkorea, 31116
    - Dankook University Hospital
  - Cheongju-si, Sydkorea, 28644
    - Chungbuk National University Hospital
  - Chuncheon, Sydkorea, 24289
    - Kangwon National University Hospital
  - Daegu, Sydkorea, 42601
    - Keimyung University Dongsan Hospital
  - Daejeon, Sydkorea, 35015
    - Chungnam national university hospital
  - Goyang-si, Sydkorea, 10380
    - Inje University Ilsan Paik Hospital
  - Guri-si, Sydkorea, 471-701
    - Hanyang University Guri Hospital
  - Gwangju, Sydkorea, 61469
    - Chonnam National University Hospital
  - Gyeonggi-do, Sydkorea, 13496
    - CHA Bundang Medical Center, CHA University
  - Incheon, Sydkorea, 21565
    - Gachon University Gil Medical Center
  - Incheon, Sydkorea, 22322
    - Inha University Hospital
  - Jeju Special, Sydkorea, 63241
    - Jeju National University Hospital
  - Sejong-si, Sydkorea, 30099
    - Chungnam National University Hospital 1
  - Seongnam, Sydkorea, 13620
    - Seoul National University Bundang Hospital
  - Seoul, Sydkorea, 03080
    - Seoul National University Hospital
  - Seoul, Sydkorea, 05505
    - Asan Medical Center
  - Seoul, Sydkorea, 06351
    - Samsung Medical Center
  - Seoul, Sydkorea, 02841
    - Korea University Anam Hospital
  - Seoul, Sydkorea, 06591
    - The Catholic University of Korea Seoul St Mary s Hospital
  - Seoul, Sydkorea, 152-703
    - Korea University Guro Hospital
  - Seoul, Sydkorea, 07985
    - Ewha Womans University Mokdong Hospital
  - Seoul, Sydkorea, 120-752
    - Severance Hospital Yonsei University Health System
  - Seoul, Sydkorea, 130 050
    - Kyung Hee University Hospital
  - Seoul, Sydkorea, 03312
    - The Catholic University of Korea Seoul St Marys Hospital
  - Seoul, Sydkorea, 04763
    - Hanyang University Hospital
  - Seoul, Sydkorea, 03080
    - Seoul National University Hospital 1
  - Suwon, Sydkorea, 16499
    - Ajou University Hospital
  - Wŏnju, Sydkorea, 220-701
    - Wonju Severance Christian Hospital
  - Yongin-si, Sydkorea, 16995
    - Yongin Severance Hospital
Taiwan
- - Changhua, Taiwan, 50006
    - Changhua Christian Hospital
  - Kaohsiung City, Taiwan, 82445
    - E-DA Hospital
  - Kaohsiung City, Taiwan, 80756
    - Kaohsiung Medical University Chung Ho Memorial Hospital
  - New Taipei City, Taiwan, 22060
    - Far Eastern Memorial Hospital
  - New Taipei City, Taiwan, 25160
    - Mackay Memorial Hospital
  - Taichung, Taiwan, 40447
    - China Medical University Hospital
  - Taipei, Taiwan, 10002
    - National Taiwan University Hospital
  - Taipei, Taiwan, 11490
    - TRI-Service General Hospital
  - Taipei, Taiwan, 106
    - Cathay General Hospital
  - Taipei, Taiwan, 116
    - Taipei Municipal Wanfang Hospital
  - Taipei, Taiwan, 112201
    - Taipei Veterans General Hospital
  - Taoyuan County, Taiwan, 33305
    - Chang Gung Memorial Hospital- Linkou
Tjekkiet
- - Brandýs nad Labem, Tjekkiet, 250 01
    - Medicus Services s.r.o.
  - Brandýs nad Labem, Tjekkiet, 25001
    - Interni ordinace s.r.o
  - Brno, Tjekkiet, 636 00
    - Vojenská Nemocnice Brno
  - Brno, Tjekkiet, 65691
    - Fakultni nemocnice u sv. Anny v Brne
  - Broumov, Tjekkiet, 550 01
    - Edumed s.r.o.
  - Bílovec, Tjekkiet, 743 01
    - HUMANITAS spol. s r.o.
  - Chomutov, Tjekkiet, 430 02
    - Ordinace pro choroby srdce s.r.o.
  - Chrudim, Tjekkiet, 537 01
    - MUDr. Jan Hubac s.r.o.
  - Jablonec nad Nisou, Tjekkiet, 46601
    - Kardiologie KarMa s.r.o
  - Kroměříž, Tjekkiet, 767 01
    - Lunacor s.r.o. - Ambulance kardiologie Centrum pro choroby srdce a cev
  - Litovel, Tjekkiet, 78401
    - Kardio Interna s.r.o.
  - Olomouc, Tjekkiet, 77900
    - Fakultni nemocnice Olomouc
  - Olomouc, Tjekkiet, 77900
    - PreventaMed, s.r.o.
  - Olomouc, Tjekkiet, 779 00
    - MUDr. Zdenek Vomacka kardiologie a interna s.r.o.
  - Ostrava Poruba, Tjekkiet, 708 52
    - Cerebrovaskularni poradna s.r.o.
  - Pardubice, Tjekkiet, 530 03
    - Pardubicka krajska nemocnice a s
  - Pilsen, Tjekkiet, 304 60
    - Fakultní nemocnice Plzen
  - Prague, Tjekkiet, 100 34
    - Fakultni nemocnice Kralovske Vinohrady
  - Prague, Tjekkiet, 128 00
    - Vseobecna Fakultni nemocnice v Praze
  - Prague, Tjekkiet, 150 06
    - Fakultni nemocnice v Motole
  - Prague, Tjekkiet, 158 00
    - MUDr. Eva Zídkova
  - Prague, Tjekkiet, 101 00
    - MUDr. Jan KVASNICKA CSc. Angiologie kardiologie a interna
  - Prague, Tjekkiet, 110 00
    - Nemocnice Na Frantisku
  - Prague, Tjekkiet, 16902
    - Ustredni vojenske nemocnice Praha
  - Příbram, Tjekkiet, 26101
    - Centrum klinickeho vyzkumu
  - Slaný, Tjekkiet, 274 01
    - Nemocnice Slany, interni oddeleni
  - Trutnov, Tjekkiet, 541 01
    - Interni ambulance
  - Uherské Hradiště, Tjekkiet, 68601
    - Interni ambulance Dr.Stanislav Zemek
  - Zlín, Tjekkiet, 760 01
    - Cardio Research s r o
  - České Budějovice, Tjekkiet, 37001
    - Nemocnice Ceske Budejovice a s
Tyrkiet (Türkiye)
- - Afyonkarahisar, Tyrkiet (Türkiye), 03200
    - Afyon Kocatepe University Medical Faculty
  - Ankara, Tyrkiet (Türkiye), 06100
    - Turkiye Yuksek Ihtisas Training and Research Hospital
  - Antalya, Tyrkiet (Türkiye), 07070
    - Akdeniz University Medical Faculty
  - Istanbul, Tyrkiet (Türkiye), 34899
    - Marmara University Pendik Training Hospital
  - Izmir, Tyrkiet (Türkiye), 35340
    - Dokuz Eylul University Medical Faculty
  - Kayseri, Tyrkiet (Türkiye), 38039
    - Erciyes University Medical Faculty
  - Mersin, Tyrkiet (Türkiye), 33020
    - Mersin University Medical Faculty
  - Mersin, Tyrkiet (Türkiye), 33330
    - Mersin University Medical Faculty Hospital
  - Samsun, Tyrkiet (Türkiye), 55139
    - Ondokuz Mayis University
Tyskland
- - Altenburg, Tyskland, 04600
    - Klinikum Altenburger Land GmbH
  - Bad Friedrichshall, Tyskland, 74177
    - Klinikum am Plattenwald
  - Bad Homburg, Tyskland, 61348
    - Kardiologische Praxis Dr. med. univ. Jungmair
  - Bad Oeynhausen, Tyskland, 32545
    - Ruhr Universitat Bochum Diabeteszentrum
  - Bamberg, Tyskland, 96049
    - Dres. Haas Kirschner Wagner
  - Berlin, Tyskland, 10249
    - Vivantes Klinikum im Friedrichshain
  - Berlin, Tyskland, 13509
    - Vivantes Humboldt Klinikum
  - Berlin, Tyskland, 12200
    - Charite Campus Benjamin Franklin
  - Berlin, Tyskland, 10559
    - Augentagesklinik Spreebogen Berlin GbR
  - Berlin, Tyskland, 10967
    - Vivantes Klinikum Am Urban, Abt. fur Kardiologie
  - Berlin, Tyskland, 12621
    - Vivantes Klinikum Hellersdorf
  - Beuel, Tyskland, 53225
    - GFO Kliniken Bonn, Betriebsstaette St. Marien
  - Bielefeld, Tyskland, 33604
    - Klinikum Bielefeld
  - Coburg, Tyskland, 96450
    - Regiomed Klinikum Coburg
  - Dachau, Tyskland, 85221
    - Medizinisches Versorgungszentrum (MVZ) Dachau
  - Deggingen, Tyskland, 73326
    - Gemeinschaftspraxis
  - Dessau, Tyskland, 06846
    - Praxis-Dr. Frank Menzel
  - Dresden, Tyskland, 01067
    - Städtisches Klinikum Dresden
  - Dresden, Tyskland, 01099
    - FAZ Dresden-Neustadt GbR
  - Dresden, Tyskland, 01277
    - Hausärztlich-Kardiologisches MVZ Am Felsenkeller GmbH
  - Elsterwerda, Tyskland, 04910
    - ZKS Südbrandenburg GMBH
  - Essen, Tyskland, 45355
    - Medizentrum Essen Borbeck
  - Essen, Tyskland, 45355
    - Studienzentrum
  - Essen, Tyskland, 45355
    - Gemeinschaftspraxis Dres. Hagemann und Breiderhoff
  - Frankfurt, Tyskland, 60596
    - ClinPhenomics GmbH Co KG Studienzentrum Frankfurt
  - Freiburg im Breisgau, Tyskland, 79106
    - Universitaetsklinikum Freiburg
  - Hamburg, Tyskland, 22763
    - Asklepios Klinik Altona
  - Hamburg, Tyskland, 22415
    - Praxis Dr. Cornelia Schiewe
  - Hamburg, Tyskland, 20099
    - ClinPhenomics GmbH Co KG Studienzentrum Hamburg
  - Hamburg, Tyskland, 20099
    - Medizinisches Versorgungszentrum Prof. Mathey, Prof. Schofer GmbH
  - Haßloch, Tyskland, 67454
    - Killat Dr. Holger Kardiologische Praxis
  - Kassel, Tyskland, 34121
    - Ambulantes Herzzentrum Kassel
  - Kiel, Tyskland, 24105
    - Universitaetsklinikum Schleswig Holstein Campus Kiel
  - Ludwigshafen, Tyskland, 67063
    - Klinikum Ludwigshafen
  - Mainz, Tyskland, 55131
    - Katholisches Klinikum Mainz; Innere Medizin I- Kardiologie
  - Mannheim, Tyskland, 68165
    - Praxis Für Pneumologie Und Allergologie
  - Neuwied, Tyskland, 56564
    - Marienhaus Klinikum
  - Nuremberg, Tyskland, 90402
    - GP Dr. Haggenmiller PD Dr. Michael Jeserich
  - Papenburg, Tyskland, 26871
    - Kardiologische Praxis Papenburg
  - Stuhr, Tyskland, 28816
    - Praxisgemeinschaft Stuhr-Brinkum
  - Tübingen, Tyskland, 72076
    - Universitaetsklinikum Tuebingen
  - Wermsdorf, Tyskland, 04779
    - Kardiologische Praxis
  - Witten, Tyskland, 58455
    - Forschungszentrum Ruhr
  - Worms, Tyskland, 67550
    - Stadtkrankenhaus Worms
  - Wuppertal, Tyskland, 42283
    - HELIOS Klinikum Wuppertal GmbH
Ungarn
- - Baja, Ungarn, 6500
    - Lausmed Egeszsegugyi es Szolg. Kft.
  - Balatonfüred, Ungarn, 8230
    - DRC Gyogyszervizsgalo Kozpont Kft
  - Budapest, Ungarn, 1036
    - Obudai Egeszsegugyi Centrum Kft
  - Budapest, Ungarn, 1088
    - Semmelweis Egyetem
  - Budapest, Ungarn, 1096
    - Gottsegen György Országos Kardiológiai Intézet
  - Budapest, Ungarn, 1023
    - Budai Irgalmasrendi Kórház
  - Budapest, Ungarn, 1122
    - Semmelweis Egyetem Városmajori Szív- és Érgyógyászati Klinika
  - Budapest, Ungarn, 1106
    - Bajcsy-Zsilinszky Kórház és Rendelőintézet
  - Budapest, Ungarn, 1051
    - Belvaros-Lipotvaros Egeszsegugyi Szolgalat
  - Budapest, Ungarn, 1085
    - Szt. Rokus Hosp
  - Budapest, Ungarn, 1132
    - Med-Tima Kft
  - Budapest, Ungarn, 1152
    - Uno Medical Trials Ltd.
  - Budapest, Ungarn, 1097
    - Del Pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet Szent Laszlo Telephely
  - Békéscsaba, Ungarn, 5600
    - Belgyogyaszati es Kardiologiai Maganrendelo
  - Debrecen, Ungarn, 4032
    - Debreceni Egyetem
  - Debrecen, Ungarn, 4025
    - Belinus Orvosi es Szamtech. Bt.
  - Debrecen, Ungarn, 4032
    - Debreceni Egyetem 1
  - Gyula, Ungarn, 5700
    - Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz
  - Gyöngyös, Ungarn, 3200
    - Bugat Pal Korhaz
  - Hatvan, Ungarn, 3000
    - BKS Research Kft
  - Hódmezővásárhely, Ungarn, 6800
    - Csongrád Megyei Egészségügyi Ellátó Központ Hódmezővásárhely
  - Kaposvár, Ungarn, 7400
    - Somogy Megyei Kaposi Mor Oktato Korhaz
  - Kecskemét, Ungarn, 6000
    - Bács-Kiskun Megyei Kórház
  - Komárom, Ungarn, 2900
    - Selye Janos Korhaz es Rendelointezet
  - Miskolc, Ungarn, 3530
    - IPR Hungary Kft
  - Mosonmagyaróvár, Ungarn, 9200
    - Karolina Korhaz-Rendelointezet
  - Mosonmagyaróvár, Ungarn, 9200
    - TaNaMed Kft.
  - Nyíregyháza, Ungarn, H-4405
    - Borbanya Praxis Eu. Kft.
  - Orosháza, Ungarn, 5900
    - Dr. Nagy Laszlo Kardiologiai Maganrendeles
  - Pécs, Ungarn, 7623
    - Coromed-Smo Kft
  - Szeged, Ungarn, 6725
    - Szegedi Tudomanyegyetem
  - Szolnok, Ungarn, 5000
    - Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointez
  - Szombathely, Ungarn, 9700
    - Markusovszky Egyetemi Oktatokorhaz
  - Székesfehérvár, Ungarn, 8000
    - Vita Verum Medical Egeszsegugyi Szolgaltato Bt
  - Zalaegerszeg, Ungarn, 8900
    - Belvarosi Egeszseghaz Kft
  - Zalaegerszeg, Ungarn, 8900
    - Obudai Egeszsegugyi Centrum Kft 1

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

18 år og ældre (Voksen, Ældre voksen)

Tager imod sunde frivillige

Ingen

Beskrivelse

Inklusionskriterier:

Minimumsalder på 18 år
Medicinsk stabil og velegnet til kronisk antitrombotisk behandling
Atrieflimren berettiget til at modtage antikoagulering
Deltageren skal opfylde en eller begge af følgende kategorier af risikofaktorer (a eller b): a) en eller flere af følgende risikofaktorer: i) alder mindre end eller lig med 75 år, ii) anamnese med et klinisk symptomatisk slagtilfælde. b) to eller flere af følgende risikofaktorer: i) alder mellem 65 og 74 år, ii) hypertension, iii) diabetes mellitus, iv) aterosklerotisk vaskulær sygdom, v) hjertesvigt

Ekskluderingskriterier:

Hæmodynamisk signifikant klapsygdom, der potentielt vil kræve kirurgisk klapudskiftning under undersøgelsen
Enhver anden tilstand end AF, der kræver kronisk antikoagulering

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Primært formål: Behandling
Tildeling: Randomiseret
Interventionel model: Parallel tildeling
Maskning: Dobbelt

Antal våben

Våben og indgreb

Deltagergruppe / Arm	Intervention / Behandling
Eksperimentel: Milvexian Deltagerne vil modtage milvexian 100 milligram (mg) oralt, to gange dagligt og placebo, der matcher apixaban fra dag 1 til slutningen af behandlingen (EOT). Deltagere efter EOT-besøget kan have mulighed for at modtage åben-label apixaban i den passende dosis (5 mg eller 2,5 mg, to gange dagligt), som sponsoren giver en 30-dages forsyning til.	Medicin: Milvexian Milvexian vil blive administreret oralt. Medicin: Placebo Milvexian matchende milvexian placebo vil blive administreret oralt.
Aktiv komparator: Apixaban Deltagerne vil modtage en placebo, der matcher milvexian, og en kapsel indeholdende apixaban 5 mg eller 2,5 mg oralt, to gange dagligt. Deltagere efter EOT-besøget kan have mulighed for at modtage åbent apixaban (5 mg eller 2,5 mg, to gange dagligt) i den passende dosis, som sponsoren giver en 30-dages forsyning til.	Medicin: Apixaban Apixaban vil blive indgivet oralt. Medicin: Apixaban placebo Apixaban-matchende apixaban placebo vil blive indgivet oralt.

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Tid til den første forekomst af sammensat endepunkt af slagtilfælde og systemisk emboli i det ikke-centrale nervesystem (CNS) Tidsramme: Op til 4 år	Tiden til den første forekomst af sammensat endepunkt for slagtilfælde og ikke-CNS systemisk emboli vil blive rapporteret.	Op til 4 år

Sekundære resultatmål

Resultatmål	Foranstaltningsbeskrivelse	Tidsramme
Tid til den første forekomst af International Society of Thrombosis and Hemostasis (ISTH) større blødning Tidsramme: Op til 4 år	Tiden til den første forekomst af ISTH større blødning vil blive rapporteret.	Op til 4 år
Tid til den første forekomst af sammensætningen af ISTH større og klinisk relevant ikke-større (CRNM) blødning Tidsramme: Op til 4 år	Tiden til den første forekomst af den sammensatte ISTH major- og CRNM-blødning vil blive rapporteret.	Op til 4 år
Tid til den første forekomst af sammensat endepunkt af kardiovaskulær (CV) død, myokardieinfarkt (MI), slagtilfælde og ikke-CNS systemisk emboli Tidsramme: Op til 4 år	Tiden til den første forekomst af sammensat endepunkt af CV død, MI, slagtilfælde og ikke-CNS systemisk emboli vil blive rapporteret.	Op til 4 år
Tid til CV-død Tidsramme: Op til 4 år	Tid til CV død vil blive rapporteret.	Op til 4 år
Tid til den første forekomst af sammensat endepunkt af dødsfald af alle årsager, hjerteinfarkt, slagtilfælde og ikke-CNS systemisk emboli Tidsramme: Op til 4 år	Tid til den første forekomst af sammensat endepunkt af dødsfald af alle årsager, MI, slagtilfælde og ikke-CNS systemisk emboli vil blive rapporteret.	Op til 4 år
Tid til den første forekomst af sammensat endepunkt af CV-død, MI, slagtilfælde, akut lemmeriskæmi (ALI) og akut hospitalsindlæggelse for vaskulær årsag af iskæmisk natur Tidsramme: Op til 4 år	Tid til den første forekomst af sammensat endepunkt af CV-død, MI, slagtilfælde, ALI [enhver uventet revaskularisering eller amputation af iskæmisk lem]) og akut indlæggelse på grund af vaskulær årsag af iskæmisk natur (inklusive dyb venetrombose [DVT] og lungeemboli [ PE]) vil blive rapporteret.	Op til 4 år
Tid til den første forekomst af sammensat slutpunkt for slagtilfælde, ikke-CNS-systemisk emboli og isth større blødning Tidsramme: Op til 4 år	Tid til den første forekomst af sammensat endepunkt for slagtilfælde, ikke-CNS-systemisk emboli og isth større blødning vil blive rapporteret.	Op til 4 år

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Janssen Research & Development, LLC

Samarbejdspartnere

Bristol-Myers Squibb

Efterforskere

Studieleder: Janssen Research & Development, LLC Clinical Trial, Janssen Research & Development, LLC

Publikationer og nyttige links

Den person, der er ansvarlig for at indtaste oplysninger om undersøgelsen, leverer frivilligt disse publikationer. Disse kan handle om alt relateret til undersøgelsen.

Generelle publikationer

Jain SS, Mahaffey KW, Pieper KS, Shimizu W, Potpara T, Ruff CT, Kamel H, Lewis BS, Cornel JH, Kowey PR, Horrow J, Strony J, Plotnikov AN, Li D, Weng S, Donahue J, Gibson CM, Steg PG, Mehran R, Weitz JI, Johnston SC, Hankey GJ, Harrington RA, Lam CSP; LIBREXIA AF Trial Investigators and Committees. Milvexian vs apixaban for stroke prevention in atrial fibrillation: The LIBREXIA atrial fibrillation trial rationale and design. Am Heart J. 2024 Nov;277:145-158. doi: 10.1016/j.ahj.2024.08.011. Epub 2024 Aug 29.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

11. april 2023

Primær færdiggørelse (Anslået)

31. oktober 2026

Studieafslutning (Anslået)

31. oktober 2026

Datoer for studieregistrering

Først indsendt

24. februar 2023

Først indsendt, der opfyldte QC-kriterier

24. februar 2023

Først opslået (Faktiske)

7. marts 2023

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

5. juni 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

4. juni 2026

Sidst verificeret

1. juni 2026

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

CR109220
70033093AFL3002 (Anden identifikator: Janssen Research & Development, LLC)
2022-501419-15-00 (Registry Identifier: EUCT number)

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

IPD-planbeskrivelse

Datadelingspolitikken for Janssen Pharmaceutical Companies of Johnson & Johnson er tilgængelig på www.janssen.com/clinical-trials/transparency. Som nævnt på dette websted kan anmodninger om adgang til undersøgelsesdataene indsendes gennem Yale Open Data Access (YODA) projektwebsted på yoda.yale.edu

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Studerer et amerikansk FDA-reguleret enhedsprodukt

Ingen

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Kliniske forsøg med Atrieflimren

W.L.Gore & Associates

Afsluttet

Sikkerhed og effektivitet af GORE® septal occluder til behandling af Ostium Secundum atrial septal defekter

Septal defekt, atrial

Forenede Stater
Pusan National University Hospital

Ikke rekrutterer endnu

Biomarkører, der forudsiger atrielle episoder med høj frekvens i modtagere af hjerteimplanterbare elektroniske anordninger

Hjerteimplanterbar elektronisk enhed | Atrial High Rate Episode

Korea, Republikken
W.L.Gore & Associates

Afsluttet

Langsigtet sikkerhedsundersøgelse af GORE® HELEX® septal occluder

Septal defekt, atrial

Forenede Stater
Academisch Medisch Centrum - Universiteit van Amsterdam...

Tilmelding efter invitation

Quinidin versus Verapamil i kortkoblet idiopatisk ventrikulær fibrillation (QUEEN-IVF)

Kortkoblet idiopatisk ventrikulær fibrillation

Holland
Henry Ford Health System

Trukket tilbage

Iatrogen atrial septal defekt undersøgelse (iASD) (iASD)

Septal defekt, atrial

Forenede Stater
Centre Hospitalier Universitaire, Amiens
Henri Mondor University Hospital

Rekruttering

Atrial belastning i septisk chok (ALARMS)

Septisk chok | Kritisk pleje | Transthorax ekkokardiografi | Speckle Tracking | Reproducerbarhed | Venstre atrial belastning | Højre atrial belastning | Ekkokardiografisk software

Frankrig
Assiut University

Trukket tilbage

Resultater af transkateter ASD-lukning styret af 3D-TEE

ASD2 (Secundum atrial septal defekt)
First Affiliated Hospital of Ningbo University

Afsluttet

Prospektiv, multicenter, randomiseret kontrolleret, ikke-inferior klinisk undersøgelse for at evaluere sikkerheden og effektiviteten af radiofrekvensoverført punkteringssystem i atrial septul

Evaluering af radiofrekvensoverført punkteringssystem | Atrial septum punktering

Kina
Prof. Dr. med. Ingo Eitel

Rekruttering

SGLT2 -hæmning til reduktion af kardiovaskulær slutpunkt i hypertension (SGLT2-HYPE)

Atrial hypertension

Tyskland
Nobles Medical Technologies II Inc

Tilmelding efter invitation

Sting lukning af PFO og septal reparation (STITCH)

Foramen Ovale, Patent | Septal defekt, atrial | Septaldefekt, Hjerte

Forenede Stater, Italien

Kliniske forsøg med Milvexian

Janssen Research & Development, LLC

Afsluttet

En undersøgelse af JNJ-70033093 (Milvexian) hos raske voksne deltagere

Sund og rask

Forenede Stater
Janssen Research & Development, LLC
Bristol-Myers Squibb

Afsluttet

En undersøgelse af Milvexian hos deltagere efter et nyligt akut koronarsyndrom (LIBREXIA-ACS)

Akut koronarsyndrom

Forenede Stater, Frankrig, Tyskland, Israel, Japan, Kina, Belgien, Danmark, Australien, Holland, Taiwan, Det Forenede Kongerige, Italien, Indien, Kroatien, Portugal, Singapore, Grækenland, Canada, Malaysia, Vietnam, Filippinerne, New... og mere
Janssen Research & Development, LLC
Bristol Myers Squibb Company (BMS)

Aktiv, ikke rekrutterende

En undersøgelse af Milvexian hos deltagere efter et akut iskæmisk slagtilfælde eller højrisiko forbigående iskæmisk angreb (LIBREXIA-STROK)

Iskæmisk slagtilfælde; Iskæmisk angreb, forbigående

Forenede Stater, Frankrig, Israel, Japan, Belgien, Kina, Tjekkiet, Danmark, Ungarn, Taiwan, Det Forenede Kongerige, Kroatien, Italien, Hong Kong, Canada, Indien, Singapore, Portugal, Malaysia, Slovakiet, Vietnam, Tyskland, Bulgarien, S... og mere
Bristol-Myers Squibb

Afsluttet

En undersøgelse af Milvexian ved hjælp af en IV mikrotracer med yderligere formulering og sammenligning af fødevareeffekt hos raske deltagere

Sunde frivillige

Det Forenede Kongerige
Janssen Pharmaceutica N.V., Belgium

Afsluttet

En undersøgelse, der evaluerer lægemiddelinteraktion mellem Milvexian og Atorvastatin hos raske deltagere

Sund og rask

Belgien
Janssen Research & Development, LLC

Afsluttet

En undersøgelse til at vurdere vendingen af de antikoagulerende virkninger af Milvexian med 4-faktor prothrombinkomplekskoncentrat (4F-PCC) (del 1) og rekombinant human faktor VIIa (rFVIIa) (del 2) hos raske deltagere

Sund og rask

Holland
Janssen Pharmaceutica N.V., Belgium
Bristol Myers Squibb Company (BMS)

Afsluttet

En undersøgelse af Milvexian hos raske voksne kvinder

Sund Kvinde

Belgien

En undersøgelse af Milvexian Versus Apixaban hos deltagere med atrieflimren (LIBREXIA-AF)

En fase 3, randomiseret, dobbeltblind, dobbeltdummy, parallel gruppe, aktiv-kontrolleret undersøgelse til evaluering af effektiviteten og sikkerheden af ​​Milvexian, en oral faktor XIa-hæmmer, versus Apixaban hos deltagere med atrieflimren

Studieoversigt

Status

Betingelser

Intervention / Behandling

Undersøgelsestype

Tilmelding (Faktiske)

Fase

Kontakter og lokationer

Studiesteder

Deltagelseskriterier

Berettigelseskriterier

Aldre berettiget til at studere

Tager imod sunde frivillige

Beskrivelse

Studieplan

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Antal våben

Våben og indgreb

Deltagergruppe / Arm

Intervention / Behandling

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Foranstaltningsbeskrivelse

Tidsramme

Samarbejdspartnere og efterforskere

Sponsor

Samarbejdspartnere

Efterforskere

Publikationer og nyttige links

Generelle publikationer

Datoer for undersøgelser

Studer store datoer

Studiestart (Faktiske)

Primær færdiggørelse (Anslået)

Studieafslutning (Anslået)

Datoer for studieregistrering

Først indsendt

Først indsendt, der opfyldte QC-kriterier

Først opslået (Faktiske)

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

Sidst verificeret

Mere information

Begreber relateret til denne undersøgelse

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

IPD-planbeskrivelse

Lægemiddel- og udstyrsoplysninger, undersøgelsesdokumenter

Studerer et amerikansk FDA-reguleret lægemiddelprodukt

Studerer et amerikansk FDA-reguleret enhedsprodukt

Kliniske forsøg med Atrieflimren

Kliniske forsøg med Milvexian

Søg i lignende forsøg

Sponsorer og samarbejdspartnere

Medicinske tilstande

Narkotikainterventioner

CROs by country

CROs in Rwanda

Betingelser

Sjældne sygdomme

Narkotikainterventioner

Kosttilskud

Sponsor / samarbejdspartnere

Placeringer

En fase 3, randomiseret, dobbeltblind, dobbeltdummy, parallel gruppe, aktiv-kontrolleret undersøgelse til evaluering af effektiviteten og sikkerheden af Milvexian, en oral faktor XIa-hæmmer, versus Apixaban hos deltagere med atrieflimren