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En studie av Milvexian versus Apixaban hos deltakere med atrieflimmer (LIBREXIA-AF)

27. august 2026 oppdatert av: Janssen Research & Development, LLC

En fase 3, randomisert, dobbeltblind, dobbel-dummy, parallell gruppe, aktivt kontrollert studie for å evaluere effektiviteten og sikkerheten til Milvexian, en oral faktor XIa-hemmer, versus apixaban hos deltakere med atrieflimmer

Hensikten med denne studien er å evaluere om milvexian er minst like effektiv som apixaban for å redusere risikoen for sammensatt slag og systemisk emboli i ikke-sentralnervesystemet (CNS).

Studieoversikt

Status

Aktiv, ikke rekrutterende

Forhold

Atrieflimmer

Intervensjon / Behandling

Studietype

Intervensjonell

Registrering (Faktiske)

20284

Fase

Fase 3

Kontakter og plasseringer

Denne delen inneholder kontaktinformasjon for de som utfører studien, og informasjon om hvor denne studien blir utført.

Studiesteder

Argentina
- - Bahía Blanca, Argentina, B8000FTD
    - Instituto de Investigaciones Clínicas Bahia Blanca
  - Buenos Aires, Argentina, C1440CFD
    - CEMEDIC
  - Buenos Aires, Argentina, C1187AAN
    - Sanatorio Finochietto
  - Buenos Aires, Argentina, C1199
    - Hospital Italiano de Buenos Aires
  - Buenos Aires, Argentina, C1061AAS
    - CIPREC
  - Buenos Aires, Argentina, 1060
    - CEDIC Centro de Investigaciones Clinicas
  - CABA, Argentina, C1056ABJ
    - CINME Centro de Investigaciones Metabólicas
  - Capital Federal, Argentina, C1118AAE
    - Clínica y Maternidad Suizo Argentina
  - Ciudad Autonoma Buenos Aires, Argentina, C1093AAS
    - Fundacion Favaloro
  - Ciudad Autonoma Buenos Aires, Argentina, 1406
    - Consultorio Dr. Litvak Bruno
  - Ciudad Autonoma Buenos Aires, Argentina, 1428
    - Instituto Cardiovascular de Buenos Aires
  - Ciudad Autonoma Buenos Aires, Argentina, 1425
    - Consultorios Asociados de Endocrinología e Investigación Clínica Aplicada
  - Ciudad Autonoma Buenos Aires, Argentina, C1430CKE
    - Glenny Corp. S.A. - Bioclinica Argentina
  - Ciudad de Buenos Aires, Argentina, C1430EGF
    - Clinica Adventista Belgrano
  - Ciudadela, Argentina, 1702
    - Instituto Médico Elsa Pérez I.M.E.P
  - Cordooba, Argentina, X5003DCP
    - Centro Médico Colón
  - Coronel Suárez, Argentina, B7540GHD
    - Clinica Coronel Suarez
  - Córdoba, Argentina, X5000JHQ
    - Sanatorio Allende
  - Córdoba, Argentina, X5004BAL
    - Hospital Italiano de Córdoba
  - Córdoba, Argentina, 5000
    - Hospital San Roque
  - Córdoba, Argentina, X5003DCE
    - Instituto Médico DAMIC
  - Córdoba, Argentina, X5000AVE
    - CIDIM-Centro Integral de Diagnostico por Imagenes Marchegiani
  - Córdoba, Argentina, 5000
    - Clínica Privada Vélez Sarsfield
  - Córdoba, Argentina, X5000AAW
    - Instituto de Investigaciones Clínicas Córdoba
  - Córdoba, Argentina, 5000
    - Clínica Colombo
  - Córdoba, Argentina, X5002HWE
    - Instituto Privado De Especialidades Medicas S.A. Fundacion J Robert Cade
  - Córdoba, Argentina, X5004CDT
    - Hospital Cordoba
  - Córdoba, Argentina, X5006CBI
    - Centro Médico Luquez
  - Godoy Cruz, Argentina, 5501
    - CIPADI
  - Junín, Argentina, B6000BHA
    - Centro Medico Lebensohn
  - Mar del Plata, Argentina, B7600FZN
    - Instituto de Investigaciones Clinicas Mar del Plata
  - Mar del Plata, Argentina, B7600FYK
    - Centro de Investigaciones Medicas Mar del Plata
  - Mendoza, Argentina, 5500
    - Fundación Scherbovsky
  - Quilmes, Argentina, B1878GEG
    - Instituto de Investigaciones Clinicas Quilmes
  - Ramos Mejía, Argentina, B1704ETD
    - DIM Clinica Privada
  - Rosario, Argentina, S2000SDV
    - Sanatorio Parque
  - Rosario, Argentina, 2000
    - Sanatorio Britanico S.A.
  - Rosario, Argentina, 2000
    - Sanatorio de La Mujer
  - Rosario, Argentina, S2000BIF
    - Instituto de Investigaciones Clinicas de Rosario
  - Salta, Argentina, 4400
    - Centro de Investigaciones Clinicas Salta
  - Salta, Argentina, 4400
    - Centro Cardiovascular Salta
  - San Juan, Argentina, 5400
    - Investigaciones Clinicas Cuyo
  - San Miguel de Tucumán, Argentina, T4000ICL
    - Investigaciones Clinicas Tucuman
  - San Nicolás, Argentina, 2900
    - Instituto de Investigaciones Clinicas San Nicolás
  - Santa Fe, Argentina, 3000
    - Centro de Investigaciones Clinicas del Litoral
  - Santa Fe, Argentina, S3000EOZ
    - Hospital Provincial Dr. Jose Maria Cullen
  - Temperley, Argentina, B1834GUK
    - Centro de Investigaciones Medicas Temperley
  - Venado Tuerto, Argentina, S2600KUE
    - Sanatorio San Martin
  - Villa María, Argentina, X5900JKA
    - Clinica Privada Fusavim SRL
  - Zárate, Argentina, 2800
    - Instituto de Investigaciones Clínicas Zárate
Australia
- - Adelaide, Australia, 5042
    - Flinders Medical Centre
  - Brisbane, Australia, 4066
    - Advara HeartCare Wesley
  - Concord, Australia, 2139
    - Concord Repatriation General Hospital
  - Frankston, Australia, 3199
    - Peninsula Heart Center
  - Garran, Australia, 2605
    - The Canberra Hospital
  - Herston, Australia, 4029
    - Royal Brisbane and Women's Hospital
  - Joondalup, Australia, 6027
    - GenesisCare Joondalup-Shenton House
  - Kotara, Australia, 2289
    - Novatrials
  - Leabrook, Australia, 5068
    - Genesiscare
  - Liverpool, Australia, 2170
    - Liverpool Hospital
  - Milton, Australia, 4064
    - Core Research Group
  - Taringa, Australia, 4068
    - AusTrials Tarragindi
Belgia
- - Aalst, Belgia, 9300
    - Algemeen Stedelijk Ziekenhuis
  - Antwerp, Belgia, 2020
    - ZNA Middelheim
  - Arlon, Belgia, 6700
    - CSL Arlon
  - Brussels, Belgia, 1070
    - CUB Hopital Erasme
  - Brussels, Belgia, 1020
    - C.H.U. Brugmann
  - Dendermonde, Belgia, 9200
    - AZ Sint-Blasius
  - Edegem, Belgia, 2650
    - UZA
  - Herk-de-Stad, Belgia, 3540
    - Jessa Ziekenhuis - Campus St.-Ursula
  - La Louvière, Belgia, 7100
    - CHU Tivoli
  - Leuven, Belgia, 3000
    - UZ Leuven
  - Mechelen, Belgia, 97770
    - AZ Sint-Maarten
  - Mol, Belgia, 2400
    - Heilig Hart Ziekenhuis Lier
  - Roeselare, Belgia, 8800
    - AZ Delta VZW
  - Turnhout, Belgia, 2900
    - AZ Turnhout
Brasil
- - Belo Horizonte, Brasil, 30150-240
    - Cardresearch - Cardiologia Assistencial
  - Belo Horizonte, Brasil, 30140-062
    - Hospital Vera Cruz
  - Belo Horizonte, Brasil, 30110-934
    - Hospital Felicio Rocho
  - Botucatu, Brasil, 18618-686
    - Fundacao para o Desenvolvimento Medico Hospitalar (UNESP Botucatu)
  - Brasília, Brasil, 70390-700
    - Rede D or Sao Luiz S A Hospital do Coracao do Brasil
  - Brasília, Brasil, 70710 149
    - Centro de Cardiologia Clinica e Pesquisa Doutora Juliana Souza Ltda CECAP Centro de Cardiologia Clinica
  - Campina Grande do Sul, Brasil, 83430-000
    - Sociedade Hospitalar Angelina Caron
  - Campinas, Brasil, 13060-080
    - Instituto de Pesquisa Clínica de Campinas
  - Campinas, Brasil, 13010-001
    - C.E.C.-Centro Especializado em Cardiologia Ltda.- Loema Medicina e Bem Estar
  - Canoas, Brasil, 92425-900
    - Hospital Universitario
  - Criciúma, Brasil, 88811-508
    - Sociedade Literaria e Caritativa Santo Agostinho Hospital Sao Jose
  - Curitiba, Brasil, 80320-320
    - Hospital Cardiológico Costantini
  - Curitiba, Brasil, 80010-030
    - Irmandade Santa Casa de Misericórdia de Curitiba -Pontifícia Universidade Católica do Paraná-PUCPR
  - Curitiba, Brasil, 80730-150
    - Nucleo de Pesquisa Clinica
  - Goiânia, Brasil, 74605-020
    - Universidade Federal de Goias - Hospital das Clinicas da UFG
  - Marília, Brasil, 17515-000
    - Instituto do Coracao de Marilia
  - Marília, Brasil, 17515-000
    - Irmandade da Santa Casa de Misericórdia de Marília
  - Natal, Brasil, 59020-035
    - Hemocardio SS Ltda
  - Passo Fundo, Brasil, 99010-120
    - Instituto Méderi de Pesquisa e Saúde
  - Pelotas, Brasil, 96015-290
    - Santa Casa de Misericordia de Pelotas
  - Porto Alegre, Brasil, 90035-903
    - Hospital das Clinicas de Porto Alegre
  - Porto Alegre, Brasil, 90160-093
    - Hospital Ernesto Dornelles
  - Porto Alegre, Brasil, 90035-001
    - Associacao Hospitalar Moinhos de Vento
  - Porto Alegre, Brasil, 90620-001
    - Fundação Universitaria de Cardiologia
  - Porto Alegre, Brasil, 90020 090
    - Irmandade da Santa Casa de Misericórdia de Porto Alegre
  - Porto Alegre, Brasil, 90110-270
    - IMV Pesquisa Cardiologica Sociedade Simples HMD COR l
  - Recife, Brasil, 50100-060
    - Pro Cardiaco Pronto Socorro Cardiologico
  - Recife, Brasil, 52051-380
    - Secretaria de Saude Hospital Agamenon Magalhaes
  - Ribeirão Preto, Brasil, 14098-900
    - Hospital Das Clinicas Da Faculdade De Medicina De RPUSP HCRP
  - Rio de Janeiro, Brasil, 22061-080
    - Impar Servicos Hospitalares S/A
  - Salvador, Brasil, 41810-010
    - Fundacao Bahiana de Cardiologia
  - Salvador, Brasil, 40170-130
    - Instituto CardioPulmonar
  - Santo André, Brasil, 09080-110
    - Pesquisare Saúde
  - São José, Brasil, 88103-460
    - Instituto de Cardiologia de Santa Catarina
  - São José do Rio Preto, Brasil, 15090-000
    - Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base
  - São Paulo, Brasil, 05403-000
    - Hospital Das Clinicas Da Faculdade De Medicina Da USP
  - São Paulo, Brasil, 04012-909
    - Instituto Dante Pazzanese de Cardiologia
  - São Paulo, Brasil, 01323-903
    - Hospital Alemao Oswaldo Cruz
  - São Paulo, Brasil, 01221-020
    - Irmandade Santa Casa de Misericordia de Sao Paulo
  - São Paulo, Brasil, 01323 000
    - FGM Clinica Paulista de Doencas Cardiovasculares Ltda IPDC Cardiologia
  - Tatuí, Brasil, 18270-170
    - Instituto de Moléstias Cardiovasculares Tatuí
  - Uberaba, Brasil
    - HC-UFTM - Hospital de Clínicas da Universidade Federal do Triângulo Mineiro
  - Vitória, Brasil, 29702-020
    - Clinica Cardioped Ltda
  - Vitória, Brasil, 29055-450
    - CEDOES
  - Votuporanga, Brasil, 15500-003
    - Santa Casa de Misericórdia de Votuporanga
Bulgaria
- - Blagoevgrad, Bulgaria, 2700
    - MHAT Puls
  - Burgas, Bulgaria
    - MC 4Life Ltd
  - Dimitrovgrad, Bulgaria, 6400
    - Medical Center Diamedical
  - Dimitrovgrad, Bulgaria, 6400
    - MHAT St. Ekaterina
  - Dupnitsa, Bulgaria, 2600
    - Medical Centre Asklepii OOD
  - Gabrovo, Bulgaria, 5300
    - Multiprofile Hospital for Active Treatment Dr. Tota Venkova
  - Haskovo, Bulgaria, 6300
    - Multiprofile Hospital for Active Treatment - Haskovo
  - Kardzhali, Bulgaria, 6600
    - Medical Center Rodopimed EOOD
  - Pazardzhik, Bulgaria, 44000
    - UMHAT 'Pulmed' OOD- MS 'Zdrave' - Pazardzhik
  - Pleven, Bulgaria, 5800
    - UMHAT 'Dr. Georgi Stranski', EAD
  - Pleven, Bulgaria, 5800
    - Medical Center Medconsult-Pleven
  - Pleven, Bulgaria, 5800
    - UMHAT 'Heart and Brain Center for Excellence'
  - Pleven, Bulgaria, 5300
    - Exacta Medica
  - Plovdiv, Bulgaria, 4000
    - UMHAT 'Sv. Georgi' EAD
  - Rousse, Bulgaria, 7000
    - Medical Center- Prolet Ltd
  - Rousse, Bulgaria, 7013
    - MC Rusemed ltd
  - Sevlievo, Bulgaria, 5402
    - Medical Center Unimed EOOD
  - Sofia, Bulgaria, 1510
    - Medical Center Hera EOOD
  - Sofia, Bulgaria, 1309
    - Multiprofile Hospital For Active Treatment National Cardiology Hospital, Ead
  - Sofia, Bulgaria, 1407
    - Acibadem City Clinic Tokuda Hospital
  - Sofia, Bulgaria, 1750
    - University Multiprofile Hospital for Active Treatment- UMHAT Sveta Anna AD
  - Sofia, Bulgaria, 1680
    - DCC Convex EOOD
  - Sofia, Bulgaria, 1431
    - Diagnostic Consultation Centre 'Alexandrovska' EOOD
  - Sofia, Bulgaria, 1233
    - National Multiprofile Transport Hospital Tsar Boris III
  - Sofia, Bulgaria, 1527
    - University Multiprofile Hospital for Active Treatment - Tsaritsa Yoanna - ISUL, EAD
  - Sofia, Bulgaria, 1431
    - UMHAT Prof. Dr. Aleksandar Chirkov
  - Sofia, Bulgaria, 1000
    - Individual Ambulatory of Cardiology
  - Sofia, Bulgaria, 1202
    - DCC Ascendent EAD
  - Sofia, Bulgaria, 1202
    - Second Multiprofile Hospital for Active Treatment MHAT - Sofia AD
  - Sofia, Bulgaria, 1233
    - MHAT Knyaginya Klementina
  - Sofia, Bulgaria, 1612
    - Meditsinski Centar - Izgrev Eood
  - Sofia, Bulgaria, 1680
    - Medical Centre Kalimat
  - Sofia, Bulgaria, 1431
    - Diagnostic Consultation Centre Alexandrovska EOOD 1
  - Stara Zagora, Bulgaria, 6003
    - UMHAT Prof. Dr. St. Kirkovich AD
  - Stara Zagora, Bulgaria, 6010
    - Medical Center ZaraMed
  - Varna, Bulgaria, 9000
    - DCC Chaika EOOD
  - Veliko Tarnovo, Bulgaria, 5000
    - MHAT Dr Stefan Cherkezov
  - Veliko Tarnovo, Bulgaria, 5000
    - Medical Center -Medika Plus
  - Yambol, Bulgaria, 8600
    - MHAT Sv. Panteleymon AD
Canada
- Alberta
  - Calgery, Alberta, Canada, T2N 1N4
    - The Governers of the University of Calgary
  - Edmonton, Alberta, Canada, T6K 4C1
    - Alberta Health services
- British Columbia
  - New Westminster, British Columbia, Canada, V3L 3W4
    - Fraser Clinical Trials Inc.
  - Surrey, British Columbia, Canada, V3V 0C6
    - Surrey Memorial Hospital
  - Victoria, British Columbia, Canada, V8R 4R2
    - Victoria Cardiac Arrhythmia Trials Inc
- Nova Scotia
  - Halifax, Nova Scotia, Canada, B3H 1V7
    - Queen Elizabeth Ii Health Sciences Centre
- Ontario
  - Brampton, Ontario, Canada, L6Z 4N5
    - Brampton Research Assoc
  - Cambridge, Ontario, Canada, N1R 7R1
    - Dr. Saul Vizel Cardiac Research Office
  - Mississauga, Ontario, Canada, L4Y 1M3
    - One Heart Care
  - Oshawa, Ontario, Canada, L1J 2K1
    - Dr. James Cha
  - Peterborough, Ontario, Canada, K9J 0B2
    - Kawartha Cardiology Clinical Trials
  - Waterloo, Ontario, Canada, N2T 0C1
    - CPS Research
- Quebec
  - Greenfield Park, Quebec, Canada, J4V 2G8
    - ViaCar Recherche Clinique Inc
  - Montreal, Quebec, Canada, H3G 1A4
    - Montreal General Hospital
  - Montreal, Quebec, Canada, H2X 0C1
    - CHUM - Pavillon B
  - Québec, Quebec, Canada, 00
    - Montreal Heart Institute
Chile
- - Puerto Varas, Chile, 5551070
    - Quantum Research
  - Santiago, Chile, 7500710
    - BioMedica Research Group
  - Santiago, Chile, 8331143
    - CeCim - Centro de Estudios Clinicos e Investigacion Medica
  - Santiago, Chile, 7500000
    - Enroll SpA
  - Santiago, Chile, 7500739
    - SMOLAM
  - Santiago, Chile
    - Sociedad Medica Cardiologica El Llano
  - Santiago, Chile, 8330024
    - Centro de Investigacion Clinica Universidad Catolica de Chile CICUC
  - Temuco, Chile, 4781156
    - Centro de Investigacion Clinica del Sur
  - Temuco, Chile, 4813299
    - Centro de Estudios Cardiologicos y de Medicina Interna
  - Viña del Mar, Chile, 2520997
    - Centro de Estudios Clinicos V Region Ltda
Danmark
- - Aarhus, Danmark, 8200
    - Aarhus University Hospital
  - Copenhagen S, Danmark, 2300
    - Amager Hospital
  - Herlev, Danmark, 2730
    - Gentofte Herlev Hospital
  - Herning, Danmark, 7400
    - Herning Regional Hospital
  - Holbæk, Danmark, 4300
    - Holbæk Sygehus
  - Hvidovre, Danmark, 2650
    - Hvidovre Hospital
  - Køge, Danmark, 4600
    - Køge Sygehus Region Sjaelland
  - Slagelse, Danmark, 4200
    - Slagelse Sygehus
  - Svendborg, Danmark, 5700
    - Odense University Hospital
Estland
- - Tallinn, Estland, 13419
    - Dr. Arvo Rosenthal LLC
Filippinene
- - Cavite, Filippinene, 4118
    - Silang Specialists Medical Center
  - Cebu City, Filippinene, 6000
    - Perpetual Succour Hospital
  - Davao City, Filippinene, 8000
    - Davao Doctors Hospital
  - Davao City, Filippinene, 8000
    - Central Lab Diabetes Wellness, Heart and Kidneys, Inc
  - Iloilo City, Filippinene, 5000
    - St.Paul's Hospital-Iloilo
  - Lipa City, Filippinene, 4217
    - Mary Mediatrix Medical Center
  - Manila, Filippinene, 1634
    - St. Luke's Medical Center
  - San Fernando City, Filippinene, 2000
    - GreenCity Medical Center
  - San Juan City, Filippinene, 1502
    - Cardinal Santos Medical Center
Forente stater
- Alabama
  - Alexander City, Alabama, Forente stater, 35010
    - Advanced Cardiovascular, LLC
  - Birmingham, Alabama, Forente stater, 35205
    - Ascension St. Vincent's Health System
  - Dothan, Alabama, Forente stater, 36303
    - Sec Clinical Research
  - Huntsville, Alabama, Forente stater, 35801
    - HH Heart Center and Heart Center
  - Mobile, Alabama, Forente stater, 36608
    - CB Flock Research Corporation
- Arizona
  - Gilbert, Arizona, Forente stater, 85297
    - Mercy Gilbert Medical Center
  - Phoenix, Arizona, Forente stater, 85016
    - Arizona Heart Hospital
  - Phoenix, Arizona, Forente stater, 85008
    - Valleywise Health Medical Center
  - Phoenix, Arizona, Forente stater, 85016
    - Arizona Arrhythmia Research Center
  - Scottsdale, Arizona, Forente stater, 85251
    - HonorHealth Neurology
  - Scottsdale, Arizona, Forente stater, 85251
    - HonorHealth Neurology 1
- Arkansas
  - Little Rock, Arkansas, Forente stater, 72211
    - Arkansas Heart Hospital
- California
  - Bakersfield, California, Forente stater, 93301
    - Bakersfield Memorial Hospital
  - Beverly Hills, California, Forente stater, 90211
    - Vitality Clinical Research
  - Chula Vista, California, Forente stater, 91911
    - Sharp Chula Vista Medical Center
  - Chula Vista, California, Forente stater, 91910
    - Chula Vista Cardiac Clinic
  - Fremont, California, Forente stater, 94538
    - Mission Cardiovascular Research Institute
  - Glendora, California, Forente stater, 91741
    - Paradise Clinical Research Group LLC
  - Long Beach, California, Forente stater, 90806
    - Miller Children's at Long Beach Medical Center
  - Los Angeles, California, Forente stater, 90033
    - University of Southern California
  - Los Angeles, California, Forente stater, 90017
    - Los Angeles Cardiology Associates
  - Merced, California, Forente stater, 95340
    - Merced Vein and Vascular Center
  - Newport Beach, California, Forente stater, 92663
    - Radin Cardiovascular Medical Group
  - Northridge, California, Forente stater, 91325
    - Valley Clinical Trials, Inc.
  - Northridge, California, Forente stater, 91324
    - California Medical Research Associates, Inc.
  - Palm Springs, California, Forente stater, 92262
    - Desert Oasis Health Care
  - Pasadena, California, Forente stater, 91105
    - Havana Research Institute LLC
  - Rancho Mirage, California, Forente stater, 92270
    - Eisenhower Desert Cardiology Center
  - Redwood City, California, Forente stater, 94063
    - Stanford Health Care
  - San Diego, California, Forente stater, 92123
    - San Diego Cardiac Center
  - Santa Ana, California, Forente stater, 92705
    - Syrentis Clinical Research
  - Stockton, California, Forente stater, 95204
    - Ramin Manshadi, MD
  - Torrance, California, Forente stater, 90502
    - UCLA School of Medicine
  - Ventura, California, Forente stater, 93003
    - Cardiology Associates Medical Group
  - Vista, California, Forente stater, 92083
    - North County Internal Medicine
  - Walnut Creek, California, Forente stater, 94598
    - John Muir Physician Network Clin. Research Center
- Colorado
  - Aurora, Colorado, Forente stater, 80012
    - Aurora Denver Cardiology Associates
  - Denver, Colorado, Forente stater, 80218
    - Aurora Denver Cardiology Associates 1
  - Wheat Ridge, Colorado, Forente stater, 80033
    - Paradigm Clinical Research Centers, Inc.
- Connecticut
  - Bridgeport, Connecticut, Forente stater, 06610
    - Bridgeport Hospital
  - Danbury, Connecticut, Forente stater, 06810
    - Western Connecticut Health Network/Danbury Hospital
  - Stamford, Connecticut, Forente stater, 06905
    - Cardiology Associates of Fairfield County
  - Trumbull, Connecticut, Forente stater, 06611
    - PriMed Physicians, A Member of NE Medical Group
- Delaware
  - Newark, Delaware, Forente stater, 19713
    - Cardiology Physicians
- District of Columbia
  - Washington D.C., District of Columbia, Forente stater, 20037
    - George Washington University School of Medicine
- Florida
  - Altamonte Springs, Florida, Forente stater, 32714
    - Orlando Heart Specialists
  - Brandon, Florida, Forente stater, 33511
    - Bay Area Cardiology Associates, P.A. - Brandon Office
  - Clearwater, Florida, Forente stater, 33756
    - Clearwater Cardiovascular Consultants
  - Daytona Beach, Florida, Forente stater, 32117
    - Cardiology Associates Research Company
  - Daytona Beach, Florida, Forente stater, 32114
    - Cardiology Consultants
  - DeLand, Florida, Forente stater, 32720
    - Accel Research Sites
  - Gainesville, Florida, Forente stater, 32605
    - The Cardiac & Vascular Institute Research Foundation
  - Gainesville, Florida, Forente stater, 32610-0226
    - University of Florida College of Medicine
  - Jacksonville, Florida, Forente stater, 32216
    - East Coast Institute for Research
  - Lakeland, Florida, Forente stater, 33805
    - Watson Clinic
  - Largo, Florida, Forente stater, 33777
    - Clearwater Cardiovascular Consultants 1
  - Miami, Florida, Forente stater, 33155
    - Miami Clinical Research
  - Miami, Florida, Forente stater, 33173
    - Suncoast Research Associates, LLC
  - Miami, Florida, Forente stater, 33165
    - Reliant Medical Research
  - Miramar Beach, Florida, Forente stater, 32550
    - Ascension Sacred Heart Hospital
  - New Port Richey, Florida, Forente stater, 34652
    - Suncoast Clinical Research
  - Orange City, Florida, Forente stater, 32763-9116
    - Central Florida Medical Associates
  - Palm Beach Gardens, Florida, Forente stater, 33410
    - Cardiology Partners Clinical Research Institute
  - Pensacola, Florida, Forente stater, 32501
    - Cardiology Consultants 1
  - Pompano Beach, Florida, Forente stater, 33064
    - North Broward Hospital District
  - Port Charlotte, Florida, Forente stater, 33952
    - Charlotte Heart Group Research Center
  - Safety Harbor, Florida, Forente stater, 34695
    - Coastal Cardiology Consultants
  - Sarasota, Florida, Forente stater, 34239-3513
    - Cardiovascular Center of Sarasota
  - St. Petersburg, Florida, Forente stater, 33705
    - Heart and Vascular Institute of Florida
  - Tampa, Florida, Forente stater, 33606
    - University of South Florida
  - Tampa, Florida, Forente stater, 33613
    - Florida Hospital Tampa
  - Tampa, Florida, Forente stater, 33607
    - Adtremed Inc
  - Tampa, Florida, Forente stater, 33634
    - Helping Hands Health Center dba Helping Hands Evolution Research
  - Wellington, Florida, Forente stater, 33449
    - Cardiology Partners Clinical Research Institute 1
- Georgia
  - Atlanta, Georgia, Forente stater, 30303
    - Grady Memorial Hospital
  - Atlanta, Georgia, Forente stater, 30309
    - Piedmont Heart Institute
  - Atlanta, Georgia, Forente stater, 30309
    - Piedmont Heart Institute 1
  - Augusta, Georgia, Forente stater, 30912
    - Augusta University
  - Columbus, Georgia, Forente stater, 31904
    - Columbus Regional Research Institute
  - Cumming, Georgia, Forente stater, 30041
    - Atlanta Heart Specialists
  - Gainesville, Georgia, Forente stater, 30501
    - Northeast Georgia Heart Center
  - Thomasville, Georgia, Forente stater, 31792
    - Cardiology Consultants of South Georgia Inc
- Hawaii
  - Honolulu, Hawaii, Forente stater, 96813
    - The Queens Medical Center
- Idaho
  - Coeur d'Alene, Idaho, Forente stater, 83814
    - Kootenai Medical Center
- Illinois
  - Chicago, Illinois, Forente stater, 60611
    - Northwestern University
  - Chicago, Illinois, Forente stater, 60612
    - Rush University Medical Center
  - Gurnee, Illinois, Forente stater, 60031
    - Clinical Investigation Specialists
  - Hazel Crest, Illinois, Forente stater, 60429
    - Chicago Medical Research, LLC
  - Naperville, Illinois, Forente stater, 60540
    - Midwest Cardiovascular Institute
  - O'Fallon, Illinois, Forente stater, 62269
    - Prairie Education And Research Cooperative
  - Oak Lawn, Illinois, Forente stater, 60453
    - Advocate Heart Institute
  - Peoria, Illinois, Forente stater, 61636
    - Methodist Medical Center of Illinois
  - Quincy, Illinois, Forente stater, 62301
    - Blessing Hospital
  - Rockford, Illinois, Forente stater, 61107-5059
    - OSF HealthCare Cardiovascular Institute
  - Springfield, Illinois, Forente stater, 62702
    - Springfield Clinic 1st
- Indiana
  - Bloomington, Indiana, Forente stater, 47402
    - Bloomington Hospital
  - Indianapolis, Indiana, Forente stater, 46260
    - St. Vincent Medical Group, Inc.
  - Muncie, Indiana, Forente stater, 47303
    - IU Health Ball Memorial Hospital
- Kansas
  - Kansas City, Kansas, Forente stater, 66160
    - University of Kansas Medical Center
- Kentucky
  - Crittenden, Kentucky, Forente stater, 41030
    - St. Elizabeth Physicians
  - Louisville, Kentucky, Forente stater, 40202
    - Kentuckyone Health Neurology Associates
  - Owensboro, Kentucky, Forente stater, 42303
    - Owensboro Medical Practice
- Louisiana
  - Alexandria, Louisiana, Forente stater, 71301
    - Cambridge Medical Trials
  - Bossier City, Louisiana, Forente stater, 71111
    - Grace Research, LLC - Bossier City
  - Chalmette, Louisiana, Forente stater, 70043
    - Medical Research Specialists
  - Houma, Louisiana, Forente stater, 70360
    - Cardiovascular Institute of the South
  - New Orleans, Louisiana, Forente stater, 70112
    - Tulane University School of Medicine
  - New Orleans, Louisiana, Forente stater, 70121
    - Ochsner Health System
  - Shreveport, Louisiana, Forente stater, 71103
    - Louisiana State University Health Sciences Center
  - Shreveport, Louisiana, Forente stater, 71115
    - Pierremont Cardiology
  - West Monroe, Louisiana, Forente stater, 71291
    - Clinical Trials of America 1
- Maryland
  - Annapolis, Maryland, Forente stater, 21401
    - Luminis Health Anne Arundel Medical Center
  - Bethesda, Maryland, Forente stater, 20814
    - Suburban Hospital
  - Columbia, Maryland, Forente stater, 21044
    - Johns Hopkins University
  - Rockville, Maryland, Forente stater, 20850
    - Shady Grove Office
  - Salisbury, Maryland, Forente stater, 21804
    - Tidal Health Peninsula Regional Inc.
  - Towson, Maryland, Forente stater, 21204
    - Spectrum Clinical Research, Inc.
- Michigan
  - Ann Arbor, Michigan, Forente stater, 48109
    - University of Michigan
  - Flint, Michigan, Forente stater, 48503
    - Flint Clinical Research
  - Lansing, Michigan, Forente stater, 48912
    - Sparrow Clinical Research Institute
  - Petoskey, Michigan, Forente stater, 49770
    - Michigan Heart & Vascular Institute
  - Southgate, Michigan, Forente stater, 48195
    - Revival Research Institute LLC
  - Troy, Michigan, Forente stater, 48085
    - Oakland Medical Research
  - Ypsilanti, Michigan, Forente stater, 48197
    - Trinity Health Michigan d b a Michigan Heart
- Minnesota
  - Bloomington, Minnesota, Forente stater, 55426
    - HealthPartners Institute
  - Duluth, Minnesota, Forente stater, 55805
    - Essentia Health SMDC
  - Maplewood, Minnesota, Forente stater, 55109
    - Fairview Health System
- Mississippi
  - Jackson, Mississippi, Forente stater, 39202
    - Mississippi Baptist Health Systems
  - Olive Branch, Mississippi, Forente stater, 38654
    - Olive Branch Family Medical Center
  - Tupelo, Mississippi, Forente stater, 38801
    - Cardiology Associates of North Mississippi
- Missouri
  - Columbia, Missouri, Forente stater, 65211
    - The Curators of the University of Missouri on behalf of University of Missouri Health Care
  - St Louis, Missouri, Forente stater, 63110
    - Washington University School of Medicine
  - St Louis, Missouri, Forente stater, 63136
    - St. Louis Heart and Vascular
- New Jersey
  - Bridgewater, New Jersey, Forente stater, 08807
    - Advanced Heart Care, LLC
  - Haddon Heights, New Jersey, Forente stater, 08035
    - Cardiovascular Associates of the Delaware Valley
  - Marlton, New Jersey, Forente stater, 08053
    - Virtua Medical Group, PA
  - Ridgewood, New Jersey, Forente stater, 07450
    - The Valley Hospital
  - Teaneck, New Jersey, Forente stater, 07666
    - Holy Name Medical Center
- New York
  - Cortlandt Manor, New York, Forente stater, 10567
    - NYU Hudson Valley Cardiology
  - Jamaica, New York, Forente stater, 11418
    - Jamaica Hospital Medical Center
  - Kingston, New York, Forente stater, 12401
    - Westchester Medical Center Advanced Physician Services PC
  - Laurelton, New York, Forente stater, 11413
    - Laurelton Heart Specialist, PC
  - Middletown, New York, Forente stater, 10941
    - Crystal Run Healthcare LLP
  - Mineola, New York, Forente stater, 11501
    - NYU Langone Hospital Long Island
  - New York, New York, Forente stater, 10021
    - Weill Cornell Medical College
  - New York, New York, Forente stater, 10075
    - Lenox Hill Hospital
  - The Bronx, New York, Forente stater, 10469
    - Cardiac Care & Vascular Medicine, PLLC
- North Carolina
  - Asheville, North Carolina, Forente stater, 28803
    - Asheville Cardiology Associates
  - Greensboro, North Carolina, Forente stater, 27405
    - Guilford Neurologic Associates
  - Lenoir, North Carolina, Forente stater, 28645
    - Clinical Trials of America
  - Pinehurst, North Carolina, Forente stater, 28374
    - Pinehurst Medical Clinic Inc
  - Raleigh, North Carolina, Forente stater, 27607
    - Rex Hospital
  - Sanford, North Carolina, Forente stater, 27330
    - Sanford Cardiology
  - Wilmington, North Carolina, Forente stater, 28401
    - Wilmington Health Associates
- North Dakota
  - Minot, North Dakota, Forente stater, 58701
    - Trinity Medical Group
- Ohio
  - Akron, Ohio, Forente stater, 44304
    - Summa Health System
  - Cincinnati, Ohio, Forente stater, 45219
    - The Lindner Clinical Trial Center
  - Cleveland, Ohio, Forente stater, 44109
    - The MetroHealth System
  - Cleveland, Ohio, Forente stater, 44106
    - Louis Stokes Cleveland VA Med Ctr
  - Dayton, Ohio, Forente stater, 45414
    - Dayton Heart Center
  - Maumee, Ohio, Forente stater, 43537
    - Advanced Medical Research
  - Springfield, Ohio, Forente stater, 45505
    - The Heart House
  - Zanesville, Ohio, Forente stater, 43701
    - Genesis HealthCare System
- Oklahoma
  - Bartlesville, Oklahoma, Forente stater, 74006
    - Ascension Medical Group - St. John Clinic Infectious Disease
  - Oklahoma City, Oklahoma, Forente stater, 73104
    - University of Oklahoma Health Sciences Center
  - Oklahoma City, Oklahoma, Forente stater, 73120
    - Oklahoma Heart Hospital
  - Oklahoma City, Oklahoma, Forente stater, 73135
    - South Oklahoma Heart Research
  - Tulsa, Oklahoma, Forente stater, 74104
    - St John Health System Inc
- Oregon
  - Portland, Oregon, Forente stater, 97225
    - Providence Heart Clinic
- Pennsylvania
  - Chambersburg, Pennsylvania, Forente stater, 17201
    - Chambersburg Hospital
  - Erie, Pennsylvania, Forente stater, 16507
    - Hamot Medical Center
  - Newport, Pennsylvania, Forente stater, 17074
    - Capital Area Research
  - Philadelphia, Pennsylvania, Forente stater, 19104
    - Penn Presbyterian Medical Center
  - Pittsburgh, Pennsylvania, Forente stater, 15240
    - VA Pittsburgh Healthcare System
  - Pittsburgh, Pennsylvania, Forente stater, 15213
    - Hudson Valley Cardiovascular Practice, PC
  - Sayre, Pennsylvania, Forente stater, 18840
    - Donald Guthrie Foundation
  - Scranton, Pennsylvania, Forente stater, 18510
    - Geisinger Medical Center
  - Yardley, Pennsylvania, Forente stater, 19067
    - Cardiology Consultants of Philadelphia
  - York, Pennsylvania, Forente stater, 17403-3676
    - York Hospital
- South Carolina
  - Anderson, South Carolina, Forente stater, 29621
    - AnMed Health
  - Anderson, South Carolina, Forente stater, 29621
    - Internal Medicine Associates of Anderson
  - Columbia, South Carolina, Forente stater, 29204
    - MUSC Health Heart Vascular Columbia Medical Park DT III
  - Greenville, South Carolina, Forente stater, 29607
    - St. Francis Physician Services, Inc, DBA Upstate Cardiology Research
- South Dakota
  - Rapid City, South Dakota, Forente stater, 57701
    - Black Hills Cardiovascular Research
- Tennessee
  - Jackson, Tennessee, Forente stater, 38301
    - Jackson Madison County General Hospital
  - Jackson, Tennessee, Forente stater, 38301
    - Jackson Clinic
  - Johnson, Tennessee, Forente stater, 37604
    - Wellmont CVA Heart Institute
  - Kingsport, Tennessee, Forente stater, 37660
    - Holston Medical Group
  - Knoxville, Tennessee, Forente stater, 37923-4310
    - East Tennessee Heart Consultants
  - Nashville, Tennessee, Forente stater, 37205
    - Saint Thomas Health
  - Powell, Tennessee, Forente stater, 37849
    - Cardiovascular Associates
- Texas
  - Amarillo, Texas, Forente stater, 79109
    - PharmaTex Research
  - Amarillo, Texas, Forente stater, 79124
    - Amarillo Heart Clinical Research Institute
  - Austin, Texas, Forente stater, 78705
    - Ascension Texas Cardiovascular
  - Dallas, Texas, Forente stater, 75231
    - Texas Health Dallas
  - Dallas, Texas, Forente stater, 75204
    - Baylor Research Institute
  - Fort Worth, Texas, Forente stater, 76104
    - Plaza Medical Center of Fort Worth
  - Houston, Texas, Forente stater, 77030
    - Baylor College of Medicine
  - Houston, Texas, Forente stater, 77024
    - Primecare Medical Group
  - Houston, Texas, Forente stater, 77002
    - East Texas Cardiology, PA
  - Houston, Texas, Forente stater, 77077
    - Novel Research LLC
  - Katy, Texas, Forente stater, 77493
    - West Houston Area Clinical Trial Consultants LLC
  - Kingwood, Texas, Forente stater, 77339
    - Texas Cardiology Research Center
  - Odessa, Texas, Forente stater, 79761
    - Odessa Heart Institute
  - San Antonio, Texas, Forente stater, 78215
    - Sun Research Institute
  - Sugar Land, Texas, Forente stater, 77479
    - Southwest Medical Clinic
  - Tomball, Texas, Forente stater, 77375
    - Northwest Houston Clinical Research
  - Waco, Texas, Forente stater, 76712
    - Baylor Scott and White Research Institute
- Utah
  - Clinton, Utah, Forente stater, 84015
    - Alpine Research Organization
- Virginia
  - Burke, Virginia, Forente stater, 22015
    - Burke Internal Medicine and Research
  - Roanoke, Virginia, Forente stater, 24014
    - Roanoke Heart Institute PLC
- Washington
  - Everett, Washington, Forente stater, 98201
    - Providence Regional Medical Center Everett
  - Seattle, Washington, Forente stater, 98122
    - Swedish Medical Center
  - Tacoma, Washington, Forente stater, 98405
    - Universal Research Group, LLC
- Wisconsin
  - Wausau, Wisconsin, Forente stater, 54401
    - Wausau Hospital
  - Wauwatosa, Wisconsin, Forente stater, 53226
    - Allegiance Reserach Specialists, LLC
Frankrike
- - Angers, Frankrike, 49933
    - Chu Angers - Hôpital Hôtel Dieu
  - Bayonne, Frankrike, 64109
    - Centre Hospitalier de la Côte Basque
  - Brest, Frankrike, 29200
    - CHU de Brest - Hopital de la Cavale Blanche
  - Bron, Frankrike, 69677
    - GH est - Hôpital Cardiovasculaire et Pneumologie Louis Pradel
  - Béziers, Frankrike, 34525
    - Centre Hospitalier de Beziers
  - Corbeil-Essonnes, Frankrike, 91106
    - Centre Hospitalier Sud Francilien
  - Créteil, Frankrike, 94010
    - Hopital Henri Mondor
  - Dijon, Frankrike, 21033
    - CHU Dijon
  - Le Chesnay, Frankrike, 78157
    - Hôpital André Mignot
  - Limoges, Frankrike, 87000
    - CHU de Limoges Hopital Dupuytren
  - Marseille, Frankrike, 13385
    - CHU de la Timone
  - Montauban, Frankrike, 82000
    - Clinique Du Pont De Chaume
  - Nice, Frankrike, 06002
    - Centre Hospitalier Universitaire - de Nice - Hopital Pasteur
  - Paris, Frankrike, 75018
    - Hopital Bichat - Claude Bernard
  - Paris, Frankrike, 75014
    - Hopital Saint Joseph
  - Paris, Frankrike, 75010
    - Hôpital Lariboisière
  - Paris, Frankrike, 75679
    - Hôpital Cochin
  - Paris, Frankrike, 75013
    - Hôpital Broca
  - Paris, Frankrike, 75571
    - Hôpital Saint-Antoine
  - Pau, Frankrike, 64000
    - Centre Hospitalier de Pau
  - Pessac, Frankrike, 33604
    - Groupe Hospitalier Sud - Hôpital Xavier Arnozan
  - Poitiers, Frankrike, 86000
    - CHU Poitiers - Hôpital la Milétrie
  - Rouen, Frankrike, 78000
    - Clinique Saint-Hilaire - Centre Frédéric Joliot
  - Rouen, Frankrike, 76031
    - CHU Rouen Hopital Charles Nicolle
  - Valenciennes, Frankrike, 59300
    - Polyclinique Vauban
Hellas
- - Alexandroupoli, Hellas, 68100
    - Uni General Hospital of Alexandroupolis
  - Athens, Hellas, 11527
    - Hippokration Hospital
  - Athens, Hellas, 14233
    - General Hospital of Nea Ionia 'Konstantopoulio'
  - Athens, Hellas, 115 27
    - General Hospital of Athens G Gennimatas
  - Kallithea, Hellas, 17674
    - Onasseio Cardiosurgery Hospital
  - Pátrai, Hellas, 26500
    - Patras University Hospital
  - Thessaloniki, Hellas, 56429
    - Papageorgiou General Hospital
  - Thessaloniki, Hellas, 57010
    - Papanikolaou General Hospital of Thessaloniki
  - Thessaloniki, Hellas, 56429
    - Papageorgiou General Hospital 1
India
- - Aligarh, India, 202001
    - Jawaharlal Nehru Medical College and Hospital
  - Amritsar, India, 143004
    - Fortis Escorts Heart Institute and Research Centre
  - Aurangabad, India, 431005
    - Kamal Nayan Bajaj Hospital
  - Bangalore, India, 560034
    - St. John's National Academy of Health Sciences - St. John's Medical College Hospital
  - Bangalore, India, 560069
    - Sri Jayadeva Institute
  - Belagavi, India, 590010
    - KLE's Dr. Prabhakar Kore Hospital & Medical Research Centre (MRC)
  - Bengaluru, India, 560002
    - Bangalore Medical College and Research Institute
  - Bikaner, India, 334003
    - S.P.Medical College & AG of Hospitals
  - Chennai, India, 600002
    - Tamil Nadu Government Multi Super Speciality Hospital
  - Jaipur, India, 302020
    - Eternal Heart Care Centre
  - Jaipur, India, 302006
    - S. R. Kalla Memorial General Hospital
  - Karamsad, India, 388325
    - B M Patel Cardiac Centre
  - Kochi, India, 682018
    - Lisie Hospital
  - Kolkata, India, 700020
    - IPGMER and SSKM Hospital
  - Kolkata, India, 700014
    - NRS Medical college
  - Lucknow, India, 226014
    - Sanjay Gandhi Postgraduate Institute of Medical Sciences
  - Nagar, India, 440015
    - Swasthyam Superspeciality Hospital
  - Nagpur, India, 440010
    - Arneja Heart Institute
  - Nagpur, India, 440015
    - Central India Cardiology Hospital and Research Institute
  - Nashik, India, 422005
    - Chopda Medicare And Research Centre Pvt Ltd Magnum Heart Institute
  - New Delhi, India, 110029
    - All India Institute of Medical Sciences
  - New Delhi, India, 110060
    - Clinical Research Room
  - Patna, India, 800014
    - Indira Gandhi Institute of Medical Sciences
  - Pune, India, 411011
    - KEM Hospital & Research Centre
  - Secunderabad, India, 500003
    - Yashoda Super Speciality Hospitals
  - Shivamogga, India, 577201
    - Nanjappa Hospital
  - Vijayawada, India, 520008
    - Government Siddhartha Medical College
  - Visakhapatnam, India, 530002
    - King George Hospital
Israel
- - Afula, Israel, 18101
    - Haemek Medical Center
  - Hadera, Israel, 3810101
    - Hillel Yaffe Medical Center
  - Haifa, Israel, 31048
    - Bnai Zion Medical Center
  - Haifa, Israel, 3436212
    - Carmel Medical Center
  - Holon, Israel, 58100
    - Wolfson Medical Center
  - Jerusalem, Israel, 9124001
    - Hadassah Medical Center
  - Jerusalem, Israel, 22100
    - Hadassah University Hospita Ein Kerem
  - Kfar Saba, Israel, 4428164
    - Meir Medical Center
  - Nazareth, Israel, 16100
    - Holy Family Hospital
  - Petah Tikva, Israel, 49100
    - Rabin Medical Center
  - Ramat Gan, Israel, 5262001
    - Chaim Sheba Medical Center
  - Rehovot, Israel, 7610001
    - Kaplan Medical Center
  - Rishon LeZiyyon, Israel, 70300
    - Assaf Harofeh Medical Center
  - Safed, Israel, 13100
    - Ziv Medical Center
Italia
- - Arezzo, Italia, 52100
    - Ospedale San Donato - ASL 8 Arezzo
  - Aversa, Italia, 81031
    - ASL Caserta_Presidio Ospedaliero San Giuseppe e Melorio_U.O.C. di Cardiologia
  - Bergamo, Italia, 24127
    - Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII)
  - Bergamo, Italia, 24125
    - Cliniche Humanitas Gavazzeni
  - Bologna, Italia, 40138
    - Azienda Opedaliero-Universitaria Policlinico Sant'orsola Malpighi di Bologna
  - Caserta, Italia, 81100
    - AORN Sant'Anna e San Sebastiano
  - Catania, Italia, 95124
    - P.O. Vittorio Emanuele Azienda Ospedaliero Universitaria 'Policlinico Vittorio Emanuele'
  - Catanzaro, Italia, 88100
    - AO di Catanzaro Pugliese Ciaccio
  - Ferrara, Italia, 44124
    - Arcispedale S. Anna Ferrara
  - Lecco, Italia, 23900
    - Ospedale Manzoni
  - Massa, Italia, 54100
    - Fondazione Toscana Gabriele Monasterio CNR
  - Milan, Italia, 20122
    - Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
  - Milan, Italia, 20162
    - A O Ospedale Niguarda Ca Granda
  - Modena, Italia, 41124
    - AOU Policlinico di Modena
  - Monza, Italia, 20052
    - Azienda Socio Sanitaria Territoriale di Monza Presidio San Gerardo
  - Pavia, Italia, 27100
    - Fondazione IRCCS Policlinico San Matteo
  - Perugia, Italia, 06156
    - Aou Santa Maria Della Misericordia Di Udine
  - Pisa, Italia, 56126
    - A. O.U. Pisana Ospedale di Cisanello
  - Roma, Italia, 00152
    - A.O. San Camillo Forlanini
  - Roma, Italia, 00161
    - AOU Policlinico Umberto I
  - Roma, Italia, 00157
    - Ospedale Sandro Pertini di Roma Reparto Emodinamica
  - Roma, Italia, 00168
    - Fondazione Policlinico Universitario A Gemelli IRCCS
  - Rozzano, Italia, 20089
    - Istituto Clinico Humanitas
  - Sassari, Italia, 07100
    - P.O. Ss. Annunziata
  - Torino, Italia, 10126
    - Azienda Ospedaliera Universitaria Citta Della Salute E Della Scienza Di Torino
  - Torrette Di Ancona, Italia, 60126
    - Azienda Ospedaliero Universitaria Ospedali Riuniti
Japan
- - Aichi, Japan, 486-8510
    - Kasugai Municipal Hospital
  - Bunkyō City, Japan, 113 8519
    - Tokyo Medical and Dental University Hospital
  - Chiba, Japan, 260 8677
    - Chiba University Hospital
  - Chiba, Japan, 273 8588
    - Funabashi Municipal Medical Center
  - Chikushino-shi, Japan, 818-8516
    - Saiseikai Futsukaichi Hospital
  - Fukuoka, Japan, 810 8563
    - National Hospital Organization Kyushu Medical Center
  - Fukuoka, Japan, 805-0050
    - Steel Memorial Yawata Hospital
  - Fukuoka, Japan, 812 8582
    - Kyushu University Hospital
  - Fukuoka, Japan, 819-1104
    - Junshinkai Nakamura Cardiovascular Clinic
  - Funabashi-shi, Japan, 274-8503
    - Chiba Tokushukai Hospital
  - Gifu, Japan, 500-8717
    - Gifu Prefectural General Medical Center
  - Higashiibaraki-gun, Japan, 311-3193
    - National Hospital Organization Mito Medical Center
  - Hirosaki-shi, Japan, 036-8562
    - Hirosaki University Hospital
  - Hiroshima, Japan, 734-8530
    - Hiroshima Prefectural Hospital
  - Hiroshima, Japan, 734 8551
    - Hiroshima University Hospital
  - Hokkaido, Japan, 053-8567
    - Tomakomai City Hospital
  - Hyōgo, Japan, 660-8550
    - Hyogo Prefectural Amagasaki General Medical Center
  - Isehara, Japan, 259-1193
    - Tokai University Hospital
  - Ishikawa, Japan, 924-0865
    - Public Central Hospital of Matto Ishikawa
  - Ishikawa, Japan, 920 8650
    - National Hospital Organization Kanazawa Medical Center
  - Itabashi Ku, Japan, 173 8606
    - Teikyo University Hospital
  - Kagoshima, Japan, 892-0822
    - Central Clinic
  - Kasuga-shi, Japan, 816-0864
    - Fukuoka Tokushukai Hospital
  - Kawasaki-shi, Japan, 212-0021
    - Sekishinkai Second Kawasaki Saiwai Clinic
  - Kitakyushu-shi, Japan, 802-8555
    - Kokura Memorial Hospital
  - Kumamoto, Japan, 861-4193
    - Saiseikai Kumamoto Hospital
  - Kumamoto, Japan, 860-8556
    - Kumamoto University Hospital
  - Kusatsu-shi, Japan, 525-8585
    - Seikokai Omi Medical Center
  - Kyoto, Japan, 606-8507
    - Kyoto University Hospital
  - Matsuyama, Japan, 790-0024
    - Ehime Prefectural Central Hospital
  - Mito, Japan, 310-0055
    - Seijunkai Mito Hospital
  - Miyazaki, Japan, 880-2102
    - Miyazaki Medical Association Hospital
  - Miyazaki, Japan, 885-0002
    - Miyakonojo Medical Association Hospital
  - Nagoya, Japan, 466-8650
    - Japanese Red Cross Nagoya Daini Hospital
  - Narashino-shi, Japan, 275-8580
    - Saiseikai Narashino Hospital
  - Nishi-Tokyo-shi, Japan, 202-0012
    - Miwa Heart Clinic
  - Nishinomiya Shi, Japan, 663 8501
    - Hyogo Medical University Hospital
  - Okayama, Japan, 700-8558
    - Okayama University Hospital
  - Okinawa, Japan, 902-8511
    - Naha City Hospital
  - Osaka, Japan, 540-0006
    - National Hospital Organization Osaka National Hospital
  - Osaka, Japan, 565-0871
    - Osaka University Hospital
  - Osaka, Japan, 543-0035
    - Osaka Police Hospital
  - Osaka, Japan, 530-0001
    - Watanabeigakukai Sakurabashi Watanabe Hospital
  - Osaka Sayama Shi, Japan, 589 8511
    - Kindai University Hospital
  - Sagamihara, Japan, 252-0375
    - Kitasato University Hospital
  - Saitama-shi, Japan, 339-0033
    - Iwatsuki Minami Hospital
  - Sapporo, Japan, 003-0026
    - Matsuda Hospital
  - Sapporo, Japan, 064-8570
    - Sanseikai Miyanomori Memorial Hospital
  - Sendai, Japan, 980 8574
    - Tohoku University Hospital
  - Shinagawa City, Japan, 142 8666
    - Showa University Hospital
  - Shinjuku-ku, Japan, 162-8666
    - Tokyo Women's Medical University Hospital
  - Suita-Shi, Japan, 564-8565
    - National Cerebral and Cardiovascular Center
  - Takatsuki-shi, Japan, 569-1096
    - Japanese Red Cross Takatsuki Hospital
  - Tokyo, Japan, 160-0023
    - Tokyo Medical University Hospital
  - Tokyo, Japan, 192-0038
    - Kenshinkai Minamino Cardiovascular Hospital
  - Tokyo, Japan, 181 8611
    - Kyorin University Hospital
  - Tokyo, Japan, 113 8603
    - Nippon Medical School Hospital
  - Tokyo, Japan, 173 8610
    - Nihon University Itabashi Hospital
  - Tokyo, Japan, 106-0031
    - The Cardiovascular Institute Hospital
  - Tokyo, Japan, 198-0042
    - Ome Medical Center
  - Tomakomai, Japan, 053-8506
    - Oji General Hospital
  - Toyoake, Japan, 470-1192
    - Fujita Health University Hospital
  - Toyota-shi, Japan, 471-8513
    - Toyota Memorial Hospital
  - Uwajima-shi, Japan, 798-8510
    - Uwajima City Hospital
  - Yokohama, Japan, 222-0036
    - Yokohama Rosai Hospital
  - Yokohama, Japan, 232 0024
    - Yokohama City University Medical Center
  - Yufu, Japan, 879-5593
    - Oita University Hospital
Kina
- - Beijing, Kina, 100191
    - Peking University Third Hospital
  - Beijing, Kina, 100029
    - Beijing AnZhen Hospital, Capital Medical University
  - Beijing, Kina, 100039
    - Chinese PLA General Hospital
  - Cangzhou, Kina, 61000
    - Cangzhou People's Hospital
  - Changchun, Kina, 130021
    - The First Hospital of Jilin University
  - Changchun, Kina, 130021
    - Jilin Province Peoples Hospital
  - Changsha, Kina, 410013
    - The Third XIANGYA Hospital of Central South University
  - Changsha, Kina, 410015
    - The Third Hospital of Changsha
  - Changzhou, Kina, 213004
    - Changzhou No 2 Peoples Hospital
  - Chengdu, Kina, 610041
    - West China Hospital Sichuan University
  - Chengdu, Kina, 610072
    - Sichuan Provincial Peoples Hospital
  - Chongqing, Kina, 400014
    - Chongqing General Hospital
  - Daqing, Kina, 163311
    - Heilongjiang Daqing People's Hospital
  - Dongguan, Kina, 523059
    - Dongguan People s Hospital
  - Fuzhou, Kina, 350005
    - The First Affiliated Hospital of Fujian Medical University
  - Ganzhou, Kina, 341000
    - Jiangxi Ganzhou Peoples Hospital
  - Guangzhou, Kina, 510080
    - Guangdong Provincial People's Hospital
  - Guangzhou, Kina, 510280
    - ZhuJiang Hospital of Southern Medical University
  - Guangzhou, Kina, 510080
    - The First Affiliated Hospital of Sun Yat-sen University
  - Guangzhou, Kina, 510630
    - The Third Affiliated Hospital Sun Yat sen University
  - Guiyang, Kina, 550000
    - The Affiliated Hospital of Guizhou Medical University
  - Guiyang, Kina, 550002
    - GuiZhou Privicial Peoples Hospital
  - Haikou, Kina, 570102
    - Affiliated Hospital of Hainan Medical University
  - Hangzhou, Kina, 310006
    - Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine
  - Hefei, Kina, 230601
    - The Second Hospital of Anhui Medical University
  - Hefei, Kina, 230001
    - Anhui province hospital
  - Hohhot, Kina, 010017
    - Inner Mongolia People's Hospital
  - Jieyang, Kina, 522091
    - Jieyang Peoples Hospital
  - Jinan, Kina, 250012
    - Qilu Hospital of Shandong University
  - Jining, Kina, 272011
    - Shandong Jining No.1 People's Hospital
  - Lanzhou, Kina, 730030
    - Lanzhou University Second Hospital
  - Luoyang, Kina, 471002
    - Luoyang Third People's Hospital
  - Nanchang, Kina, 330006
    - The Second Affiliated Hospital of Nanchang University
  - Nanchang, Kina, 330006
    - Jiangxi Provincial Peoples Hospital
  - Nanchang, Kina, 330009
    - Nanchang Peoples hospital
  - Ningbo, Kina, 315010
    - Ningbo First Hospital
  - Shanghai, Kina, 200032
    - Zhongshan Hospital Fudan University
  - Shanghai, Kina, 200011
    - Shanghai Ninth Peoples Hospital
  - Shanghai, Kina, 201508
    - Jinshan Hospital Fudan University
  - Shantou, Kina, 515041
    - The First Affiliated Hospital of Shantou University Medical
  - Shenyang, Kina, 110004
    - Shengjing Hospital of China Medical University
  - Shenzhen, Kina, 518052
    - Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen
  - Shijiazhuang, Kina, 050000
    - The Second Hospital of Hebei Medical University
  - Suzhou, Kina, 215006
    - The First Affiliated Hospital of Soochow University
  - Taian, Kina, 271000
    - Taian City Central Hospital
  - Taiyuan, Kina, 030013
    - Shanxi Cardiovascular Hospital
  - Taizhou, Kina, 318020
    - Taizhou First Peoples Hospital
  - Tianjin, Kina, 300052
    - Tianjin Medical University General Hospital
  - Tianjin, Kina, 300457
    - Teda International Cardiovascular Hospital
  - Tianjin, Kina, 300121
    - Tianjin People's Hospital
  - Tianjin, Kina, 300051
    - Tianjin Chest Hospital
  - Tianjin, Kina, 300140
    - Tianjin 4th Center Hospital
  - Tianjin, Kina, 300211
    - The 2nd Hospital of Tianjin Medical University
  - Wenzhou, Kina, 325000
    - The First Affiliated Hospital of Wenzhou Medical University
  - Wenzhou, Kina, 325000
    - Wenzhou Peoples Hospital
  - Wuhan, Kina, 430014
    - The Central Hospital of Wuhan
  - Wuhan, Kina, 430060
    - Union Hospital Tongji Medical College of Huazhong University of Science and Technology
  - Xi'an, Kina, 710068
    - Shaanxi Provincial Peoples Hospital
  - Xinxiang, Kina, 453003
    - The Third Affiliated Hospital of Xinxiang Medical University
  - Xuzhou, Kina
    - The Affiliated Hospital of Xuzhou Medical College
  - Yangzhou, Kina, 225001
    - Northern Jiangsu Peoples Hospital
  - Yantai, Kina, 264000
    - Yantai YuHuangDing Hospital
  - Yinchuan, Kina, 750004
    - General Hospital of Ningxia Medical Hospital
  - Zhanjiang, Kina, 524001
    - Affiliated Hospital of Guangdong Medical University
  - Zhengzhou, Kina, 450016
    - The 7th Peoples Hospital of Zhengzhou
  - Zunyi, Kina, 563099
    - Affiliated Hospital of Zunyi Medical University
Kroatia
- - Dubrovnik, Kroatia, 20000
    - General Hospital Dubrovnik
  - Karlovac, Kroatia, 47000
    - Opca bolnica Karlovac
  - Krapinske Toplice, Kroatia, 49217
    - Special Hospital for medical rehabilitation
  - Krapinske Toplice, Kroatia, 49217
    - Clinic for Cardiovascular Disease Magdalena
  - Varaždin, Kroatia, 42000
    - OB Varazdin
  - Varaždin, Kroatia, 42000
    - OB Varazdin 1
  - Zadar, Kroatia, 23000
    - Zadar General Hospital
  - Zagreb, Kroatia, 10000
    - University Hospital Dubrava
  - Zagreb, Kroatia, 10000
    - Polyclinic Bonifarm
  - Zagreb, Kroatia, 10000
    - Poliklinika Solmed
  - Čakovec, Kroatia, 40000
    - Zupanijska bolnica Cakovec
Latvia
- - Daugavpils, Latvia, LV5417
    - Daugavpils Regional Hospital
  - Riga, Latvia, LV-1002
    - Pauls Stradins Clinical University Hospital
  - Riga, Latvia, LV-1038
    - Riga East Clinical University Hospital
Litauen
- - Kaunas, Litauen, 49449
    - Saules Seimos Medicinos Centras, JSC
  - Kaunas, Litauen, 49387
    - Klinikiniai sprendimai JSC
  - Kaunas, Litauen, LT-47144
    - Kaunas Clinical Hospital, Public Institution
  - Klaipėda, Litauen, LT-92288
    - Klaipeda Seamen's Hospital, Public Institution
  - Vilnius, Litauen, LT-08661
    - Vilnius University Hospital Santariskiu Clinic, Public Institution
  - Vilnius, Litauen, LT-08406
    - Inlita, JSC
  - Vilnius, Litauen, LT-08406
    - Inmedica, JSC
  - Vilnius, Litauen, 08661
    - Vilnius University Hospital Santariskiu Clinic, Public Institution 1
Malaysia
- - Alor Star, Malaysia, 05460
    - Hospital Sultanah Bahiyah
  - Kota Bharu, Malaysia, 15200
    - Hospital University Sains Malaysia
  - Kota Kinabalu, Malaysia, 88300
    - Queen Elizabeth II Hospital
  - Kuala Lumpur, Malaysia, 50400
    - Institut Jantung Negara
  - Kuantan, Malaysia, 25100
    - Hospital Tengku Ampuan Afzan
  - Selayang Baru Utara, Malaysia, 68000
    - Universiti Teknologi Mara
  - Seri Manjung, Malaysia, 32040
    - Hospital Seri Manjung
  - Taiping, Malaysia, 34000
    - Hospital Taiping
Nederland
- - 's-Hertogenbosch, Nederland, 5223 GZ
    - Jeroen Bosch Ziekenhuis
  - Alkmaar, Nederland, 1815 JD
    - Noordwest Ziekenhuisgroep
  - Almelo, Nederland, 7609
    - ZGT Cardioresearch
  - Amersfoort, Nederland, 3813 TZ
    - Meander Medisch Centrum
  - Amsterdam, Nederland, 1081 HV
    - VUMC Amsterdam
  - Amsterdam, Nederland, 1091 AC
    - Onze Lieve Vrouwe Gasthuis
  - Delft, Nederland, 2625 AD
    - Reinier de Graaf Gasthuis
  - Deventer, Nederland, 7416 SE
    - Deventer Ziekenhuis
  - Doetinchem, Nederland
    - Slingeland Ziekenhuis
  - Ede, Nederland, 6716 RP
    - Ziekenhuis Gelderse Vallei
  - Eindhoven, Nederland, 5623 EJ
    - Catharina Ziekenhuis
  - Gouda, Nederland, 2800 BB
    - Groene Hart Ziekenhuis
  - Heerlen, Nederland, 6419 PC
    - Atrium Med.Centrum Heerlen - Afd.Interne - INT
  - Helmond, Nederland, 5707 HA
    - Elkerliek Ziekenhuis
  - Leiderdorp, Nederland, 2353 GA
    - Alrijne Ziekenhuis Leiden ; Cardiology
  - Nieuwegein, Nederland, 3435 CM
    - St. Antonius Ziekenhuis Nieuwegein
  - Nijmegen, Nederland, 6525GA
    - Radboudumc
  - Rotterdam, Nederland, 3083 AN
    - Ikazia Ziekenhuis
  - Rotterdam, Nederland, 3045 PM
    - Sint Franciscus Gasthuis
  - Sneek, Nederland, 8601 ZR
    - D & A Research
  - Tilburg, Nederland, 5022 GC
    - ETZ Elisabeth
  - Veldhoven, Nederland, 5504 DB
    - Maxima Medisch Centrum
  - Zutphen, Nederland, 7207 AE
    - Gelre Ziekenhuizen Zutphen
New Zealand
- - Auckland, New Zealand, 1030
    - Auckland City Hospital
  - Auckland, New Zealand, 0740
    - North Shore Hospital
  - Christchurch, New Zealand, 8140
    - University of Otago
  - Dunedin, New Zealand, 9016
    - Dunedin Public Hospital
  - Hamilton, New Zealand, 3200
    - Waikato Hospital
  - Hastings, New Zealand
    - Hawkes Bay Hospital
  - New Plymouth, New Zealand, 4342
    - Taranaki Base Hospital
  - Otahuhu, New Zealand, 2025
    - Middlemore Hospital
  - Rotorua, New Zealand, 3010
    - Rotorua Hospital
  - Tauranga, New Zealand, 3143
    - Tauranga Hospital
Polen
- - Biała Podlaska, Polen, 21 500
    - Wojewodzki Szpital Specjalistyczny
  - Bydgoszcz, Polen, 85-796
    - Centrum medyczne Pratia Bydgoszcz
  - Bydgoszcz, Polen, 85 231
    - NZOZ Centrum Medyczne KERmed
  - Bydgoszcz, Polen, 85 048
    - IN VIVO Sp. z o.o
  - Bydgoszcz, Polen, 85 605
    - Centrum Medyczne Intercor Sp z o o
  - Chojnice, Polen, 89 600
    - Centrum Medyczne Pratia Chojnice
  - Chorzów, Polen, 41-500
    - DIAB SERWIS Popenda Sp. Jawna Specjalistyczna Przychodnia Lekarska
  - Chorzów, Polen, 41-500
    - M2M MED Badania Spolka z o. o
  - Chrzanów, Polen, 32-500
    - Centrum Medyczne MBB-MED
  - Elblag, Polen, 82-300
    - NZOZ Twoje Zdrowie El
  - Gdansk, Polen, 80-286
    - Poradnia Kardiologiczna Jaroslaw Jurowiecki
  - Gdynia, Polen, 81-157
    - Private Practice - Dr. Krzysztof Cymerman
  - Gdynia, Polen, 81-423
    - NZOZ Procordis Pawel Miekus
  - Grodzisk Mazowiecki, Polen, 05 825
    - MCBK Iwona Czajkowska Anna Podrazka Szczepaniak S C
  - Jelenia Góra, Polen, 58 506
    - Centrum Medyczne Pratia Jelenia Gora
  - Katowice, Polen, 40-555
    - Kardio Klinika Brynow
  - Katowice, Polen, 40-282
    - Silmedic sp. z o.o
  - Katowice, Polen, 40-156
    - Clinical Medical Research Sp. z o.o.
  - Katowice, Polen, 40 081
    - Centrum Medyczne Pratia Katowice
  - Katowice, Polen, 40-752
    - Niepubliczny Zaklad Opieki Zdrowotnej
  - Kielce, Polen, 25-525
    - Specjalistyczna Poradnia Kardiologiczna i Nadcisnienia Tetniczego
  - Krakow, Polen, 30-082
    - Ewa Mirek-Bryniarska Specjalistyczna Praktyka Lekarska
  - Krakow, Polen, 30-721
    - Centrum Medyczne Linden
  - Krakow, Polen, 31 216
    - Centrum Medyczne Zdrowa J Trebacz W Zajdel s j
  - Krakow, Polen, 31-501
    - Krakowskie Centrum Medyczne Sp z o o NZOZ
  - Krakow, Polen, 31-826
    - Odzial Kardiologii i Chorob Wewnetrznych Szpital Specjalistyczny im. Ludwika Rydygiera
  - Legnica, Polen, 59-220
    - B.Miklaszewicz&D.Dabrowski CARDIMED Spolka Jawna
  - Lodz, Polen, 94-255
    - Indywidualna Specjalistyczna Praktyka Lekarska
  - Lodz, Polen, 94-048
    - NZOZ ALL-MED Centrum Medyczne Specjalistyczne Gabinety Lekarskie
  - Lodz, Polen, 91 363
    - Centrum Medyczne AMED oddzial w Lodzi
  - Lodz, Polen, 93 338
    - Instytut Centrum Zdrowia Matki Polki
  - Lodz, Polen, 91 034
    - Centrum Medyczne Med Gastr
  - Lodz, Polen, 90 302
    - SANTA FAMILIA Centrum Badan Profilaktyki i Leczenia
  - Lowicz, Polen, 99 400
    - Lowickie Centrum Kardiologii
  - Lublin, Polen, 20 049
    - 1 Wojskowy Szpital Kliniczny z Polikliniką SPZOZ w Lublinie
  - Lublin, Polen, 20 362
    - KO MED Centra Kliniczne LUBLIN
  - Lublin, Polen, 20 412
    - ETG Lublin
  - Olsztyn, Polen, 10-010
    - Futuremeds Olsztyn
  - Ostrowiec Świętokrzyski, Polen, 27-400
    - Ostrowieckie Centrum Medyczne Spolka Cywilna Anna Olech-Cudzik, Krzysztof Cudzik
  - Oświęcim, Polen, 32-600
    - Medicome Sp. z o.o.
  - Piaseczno, Polen, 05-500
    - Nzoz Heureka
  - Poznan, Polen, 60-693
    - Med-Polonia Sp. z o.o.
  - Poznan, Polen, 61 853
    - NZOZ NEURO KARD Ilkowski i Partnerzy Sp Partnerska Lekarzy
  - Przemyśl, Polen, 37-700
    - Wojewodzki Szpital im Sw Ojca Pio w Przemyslu
  - Ruda Śląska, Polen, 41-709
    - Janusz Spyra Specjalistyczna Praktyka Lekarska
  - Rzeszów, Polen, 35-055
    - Centrum Medyczne Medyk
  - Siedlce, Polen, 08-110
    - ETG Siedlce
  - Siedlce, Polen, 08-110
    - Samodzielny Publiczny Zaklad Opieki Zdrowotnej w Siedlcach
  - Skierniewice, Polen, 96-100
    - Velocity Nova spolka z ograniczona odpowiedzialnoscia
  - Warsaw, Polen, 02-793
    - ETG Warszawa
  - Warsaw, Polen, 02 637
    - Narodowy Instytut Geriatrii Reumatologii i Rehabilitacji im prof dr hab med Eleonory Reicher
  - Warsaw, Polen, 00 2015
    - FutureMeds Warszawa Centrum
  - Warsaw, Polen, 03 291
    - Futuremeds Targowek
  - Wroclaw, Polen, 53-030
    - CM Sedimed Wroclaw
  - Wroclaw, Polen, 50 368
    - Uniwersytecki Szpital Kliniczny Im Jana Mikulicza Radeckiego We Wroclawiu
  - Wroclaw, Polen, 50 981
    - 4 Wojskowy Szpital Kliniczny Z Poliklinika SP ZOZ
  - Wroclaw, Polen, 51 314
    - NZOZ Zdrowie s c Agnieszka i Donald Drozdz
  - Zamość, Polen, 22-400
    - Velocity Zamosc
  - Zamość, Polen, 22 400
    - ETG Zamość
  - Żarów, Polen, 58-130
    - Centrum Medyczne Serafin med
Portugal
- - Coimbra, Portugal, 3000-075
    - Uls Coimbra - Hosp. Univ. Coimbra
  - Covilha, Portugal, 6200-074
    - Centro Hospitalar Cova da Beira, EPE - Hospital Pêro da Covilhã
  - Figueira da Foz Municipality, Portugal, 3094-001
    - Hospital Distrital Fig Da Foz Gala
  - Lisbon, Portugal, 1649-035
    - Centro Hospitalar de Lisboa Norte Hospital Santa Maria
  - Lisbon, Portugal, 2790-134
    - Centro Hospitalar Lisboa Ocidental - Hospital São Fracisco Xavier
  - Santa Maria da Feira, Portugal, 4520-211
    - Centro Hospitalar de Entre o Douro e Vouga, E.P.E
  - Torres Novas, Portugal, 2350-325
    - Largo da Igreja Velha Edifício CCA
  - Vila Nova de Gaia, Portugal, 4434-502
    - Centro Hospitalar de Vila Nova de Gaia Espinho E P E
  - Vila Real, Portugal, 5000-508
    - Centro Hospitalar de Trás os Montes e Alto Douro- Vila Real
Romania
- - Baia Mare, Romania, 430222
    - CMI Cardiologie Dr. Calin Pop
  - Brasov, Romania, 500283
    - Centrul Medical de Diagnostic si Tratament Ambulator Neomed
  - Brasov, Romania, 500091
    - Centrul Medical Unirea SRL
  - Brăila, Romania, 810119
    - Spitalul Județean de Urgență Brăila
  - Bucharest, Romania, 050659
    - Spitalul Clinic de Urologie Prof. Dr. Theodor Burghele
  - Bucharest, Romania, 022322
    - Institutul de urgenta pentru Boli Cardiovasculare Prof. Dr. C.C. Iliescu
  - Bucharest, Romania, 010192
    - Clinica Medicala Data Plus SRL
  - Bucharest, Romania, 011794
    - Centrul Medical de Diagnostic si Tratament Ambulatoriu si Medicina Preventiva
  - Bucharest, Romania, 014142
    - S C Delta Health Care S R L
  - Cluj-Napoca, Romania, 400000
    - Spitalul Angiocare SRL
  - Iași, Romania, 700503
    - Institutul de Boli Cardiovasculare Iasi
  - Iași, Romania, 700786
    - Cardiomed SRL
  - Oradea, Romania, 410169
    - Spitalul Clinic Judetean de Urgenta Oradea
  - Piteşti, Romania, 110424
    - SAL MED Pitesti
  - Sibiu, Romania, 550245
    - Spitalul Clinic Judetean Sibiu
  - Suceava, Romania, 720049
    - Cabinet Medical Cardiologie Cojocariu Titel Razvan
  - Tg. Mures, Romania, 540136
    - Spitalul Clinic Judetean de Urgenta Targu Mures
  - Timișoara, Romania, 300043
    - Clinica Medicaliss
  - Târgu Mureş, Romania, 540143
    - Cmi Dr Podoleanu Cristian
Serbia
- - Belgrade, Serbia, 11080
    - Clinical Center Bezanijska kosa
  - Belgrade, Serbia, 11000
    - University Clinical Center of Serbia
  - Belgrade, Serbia, 11080
    - University Clinical Hospital Center Dr Dragisa Misovic- Dedi
  - Belgrade, Serbia, 11000
    - Institute for Cardiovascular diseases Dedinje
  - Belgrade, Serbia, 11000
    - University Clinical Center of Serbia 1
  - Belgrade, Serbia, 11000
    - University Clinical Center of Serbia 2
  - Belgrade, Serbia, 11040
    - Institute for Cardiovascular diseases Dedinje 1
  - Belgrade, Serbia, 11040
    - Institute for Cardiovascular diseases Dedinje 2
  - Belgrade, Serbia, 11080
    - University Clinical Hospital Center Dr Dragisa Misovic- Dedi 1
  - Kamenitz, Serbia, 21204
    - Institute of Cardiovascular Diseases of Vojvodina
  - Kragujevac, Serbia, 34000
    - Clinical Center of Kragujevac
  - Niš, Serbia, 18000
    - Clinical Center Niš
  - Niška Banja, Serbia, 18205
    - Institute for Treatment and Rehabilitation Niska Banja
  - Pančevo, Serbia, 26000
    - General Hospital Pancevo
  - Smederevo, Serbia, 11300
    - General Hospital Smederevo
  - Sremska Mitrovica, Serbia, 22000
    - General Hospital Sremska Mitrovica
  - Užice, Serbia, 31000
    - General Hospital Uzice
  - Zaječar, Serbia, 19000
    - Health Center Zajecar
Singapore
- - Singapore, Singapore, 169856
    - Singapore General Hospital
  - Singapore, Singapore, 169609
    - National Heart Centre (NHC) Singapore
Slovakia
- - Bardejov, Slovakia, 08501
    - Alian s.r.o.
  - Bardejov, Slovakia, 08501
    - Thyreomedical s r o
  - Bratislava, Slovakia, 83348
    - Narodny ustav srdcovych a cievnych chorob
  - Bratislava, Slovakia, 83101
    - Kardiovaskularne centrum, s.r.o.
  - Bratislava, Slovakia, 81104
    - Cardioconsult s.r.o.
  - Bratislava, Slovakia, 82101
    - Univerzitna nemocnica Bratislava
  - Bratislava, Slovakia, 85101
    - Veria, s.r.o Kardiologicka ambulancia
  - Brezno, Slovakia, 977 01
    - Nemocnica s poliklinikou Brezno
  - Dolný Kubín, Slovakia, 02601
    - KARDIO-ONKOLOGIA s.r.o. Kardiologicka ambulancia
  - Košice, Slovakia, 040 11
    - Východoslovenský Ústav Srdcových A Cievnych Chorôb, A.S.
  - Košice, Slovakia, 04022
    - CARDIO D&R, s.r.o.
  - Košice, Slovakia, 4001
    - Kardiologicka ambulancia Medicalgroup s.r.o.
  - Lučenec, Slovakia, 98401
    - IN-DIA s.r.o.
  - Lučenec, Slovakia, 98401
    - KARDIO 1 s.r.o.
  - Lučenec, Slovakia, 98401
    - Kardiomed, S.R.O.
  - Moldava nad Bodvou, Slovakia, 4501
    - Kardiologicka ambulancia MEDI M&M s.r.o.
  - Nitra, Slovakia, 95001
    - Fakultna nemocnica Nitra
  - Nové Zámky, Slovakia, 94052
    - Cardioinvest s.r.o.
  - Prešov, Slovakia, 08001
    - Medispol s.r.o Interna a kardiologicka ambulancia
  - Prešov, Slovakia, 08081
    - Fakultna nemocnica s poliklinikou J.A. Reimana Presov
  - Svidník, Slovakia, 08901
    - Interna SK s.r.o.
  - Žilina, Slovakia, 01001
    - MEDIVASA s.r.o.
Spania
- - A Coruña, Spania, 15006
    - Hosp Univ A Coruna
  - Alicante, Spania, 3540
    - Hosp. Gral. Univ. de Alicante
  - Barcelona, Spania, 08041
    - Hosp. de La Santa Creu I Sant Pau
  - Barcelona, Spania, 08003
    - Hosp. Del Mar
  - Barcelona, Spania, 08907
    - Hosp. Univ. de Bellvitge
  - El Palmar, Spania, 30120
    - Hosp. Univ. Virgen de La Arrixaca
  - Lleida, Spania, 25198
    - Hosp. Univ. Arnau de Vilanova de Lleida
  - Madrid, Spania, 28046
    - Hosp. Univ. La Paz
  - Madrid, Spania, 28006
    - Hosp. Univ. de La Princesa
  - Madrid, Spania, 28003
    - Hosp. Virgen de La Luz
  - Manises, Spania, 46940
    - Hosp. de Manises
  - Málaga, Spania, 29010
    - Hosp Virgen de La Victoria
  - Sabadell, Spania, 08208
    - Corporacio Sanitari Parc Tauli
  - Santiago de Compostela, Spania, 15706
    - Hosp. Clinico Univ. de Santiago
  - Valencia, Spania, 46010
    - Hosp. Clinico Univ. de Valencia
  - Valencia, Spania, 46014
    - Hosp. Clinico Univ. de Valencia 1
Storbritannia
- - Bristol, Storbritannia, BS1 3NU
    - Bristol Royal Infirmary
  - Clydebank, Storbritannia, G81 4HX
    - Golden Jubilee National Hospital
  - Dorchester, Storbritannia, DT1 2JY
    - Dorset County Hospital
  - Exeter, Storbritannia, EX2 5DW
    - Royal Devon and Exeter Hospital(Wonford)
  - High Wycombe, Storbritannia, HP11 2TT
    - Wycombe Hospital
  - Lincoln, Storbritannia, LN2 5QY
    - Lincoln County Hospital
  - London, Storbritannia, EC1A 7BE
    - Barts Hospital
  - Sheffield, Storbritannia, S5 7AU
    - Northern General Hospital
  - Stevenage, Storbritannia, SG1 4AB
    - Lister Hospital
  - Truro, Storbritannia, TR1 3LJ
    - Royal Cornwall Hospital
  - Wigan, Storbritannia, WN1 2NN
    - Wrightington Hospital,Wrightington, Wigan and Leigh NHS Trus
  - Worcester, Storbritannia, WR5 1DD
    - Worcestershire Royal Hospital
Sør -Korea
- - Anyang-si, Sør -Korea, 431-796
    - Hallym University Sacred Heart Hospital
  - Busan, Sør -Korea, 49241
    - Pusan National University Hospital
  - Busan, Sør -Korea, 47392
    - Inje University Busan Paik Hospital
  - Busan, Sør -Korea, 602 812
    - Dong-A University Hospital
  - Cheonan-si, Sør -Korea, 31116
    - Dankook University Hospital
  - Cheongju-si, Sør -Korea, 28644
    - Chungbuk National University Hospital
  - Chuncheon, Sør -Korea, 24289
    - Kangwon National University Hospital
  - Daegu, Sør -Korea, 42601
    - Keimyung University Dongsan Hospital
  - Daejeon, Sør -Korea, 35015
    - Chungnam National University Hospital
  - Goyang-si, Sør -Korea, 10380
    - Inje University Ilsan Paik Hospital
  - Guri-si, Sør -Korea, 471-701
    - Hanyang University Guri Hospital
  - Gwangju, Sør -Korea, 61469
    - Chonnam National University Hospital
  - Gyeonggi-do, Sør -Korea, 13496
    - CHA Bundang Medical Center, CHA University
  - Incheon, Sør -Korea, 21565
    - Gachon University Gil Medical Center
  - Incheon, Sør -Korea, 22322
    - Inha University Hospital
  - Jeju Special, Sør -Korea, 63241
    - Jeju National University Hospital
  - Sejong-si, Sør -Korea, 30099
    - Chungnam National University Hospital 1
  - Seongnam, Sør -Korea, 13620
    - Seoul National University Bundang Hospital
  - Seoul, Sør -Korea, 03080
    - Seoul National University Hospital
  - Seoul, Sør -Korea, 05505
    - Asan Medical Center
  - Seoul, Sør -Korea, 06351
    - Samsung Medical Center
  - Seoul, Sør -Korea, 02841
    - Korea University Anam Hospital
  - Seoul, Sør -Korea, 06591
    - The Catholic University of Korea Seoul St Mary s Hospital
  - Seoul, Sør -Korea, 152-703
    - Korea University Guro Hospital
  - Seoul, Sør -Korea, 07985
    - Ewha Womans University Mokdong Hospital
  - Seoul, Sør -Korea, 120-752
    - Severance Hospital Yonsei University Health System
  - Seoul, Sør -Korea, 130 050
    - Kyung Hee University Hospital
  - Seoul, Sør -Korea, 03312
    - The Catholic University of Korea Seoul St Marys Hospital
  - Seoul, Sør -Korea, 04763
    - Hanyang University Hospital
  - Seoul, Sør -Korea, 03080
    - Seoul National University Hospital 1
  - Suwon, Sør -Korea, 16499
    - Ajou University Hospital
  - Wŏnju, Sør -Korea, 220-701
    - Wonju Severance Christian Hospital
  - Yongin-si, Sør -Korea, 16995
    - Yongin Severance Hospital
Sør-Afrika
- - Cape Town, Sør-Afrika, 7500
    - TREAD Research
  - Centurion, Sør-Afrika, 0157
    - Johese Clinical Research
  - Johannesburg, Sør-Afrika, 2192
    - Garda, RA
  - Krugersdorp, Sør-Afrika, 1739
    - DJW Research
  - Pretoria, Sør-Afrika, 0002
    - Clinical Research Unit, University of Pretoria
  - Pretoria, Sør-Afrika, 0181
    - Into Research
  - Somerset West, Sør-Afrika, 7130
    - Dr J.M. Engelbrecht Trial Site
  - Somerset West, Sør-Afrika, 7130
    - Helderberg Research Institute
  - Tongaat, Sør-Afrika, 4399
    - Mediclinic Victoria Hospital
  - Worcester, Sør-Afrika, 6850
    - Clinical Projects Research SA (PTY) LTD
Taiwan
- - Changhua, Taiwan, 50006
    - Changhua Christian Hospital
  - Kaohsiung City, Taiwan, 82445
    - E-Da Hospital
  - Kaohsiung City, Taiwan, 80756
    - Kaohsiung Medical University Chung Ho Memorial Hospital
  - New Taipei City, Taiwan, 22060
    - Far Eastern Memorial Hospital
  - New Taipei City, Taiwan, 25160
    - Mackay Memorial Hospital
  - Taichung, Taiwan, 40447
    - China Medical University Hospital
  - Taipei, Taiwan, 10002
    - National Taiwan University Hospital
  - Taipei, Taiwan, 11490
    - Tri-Service General Hospital
  - Taipei, Taiwan, 106
    - Cathay General Hospital
  - Taipei, Taiwan, 116
    - Taipei Municipal Wanfang Hospital
  - Taipei, Taiwan, 112201
    - Taipei Veterans General Hospital
  - Taoyuan County, Taiwan, 33305
    - Chang Gung Memorial Hospital- Linkou
Tsjekkia
- - Brandýs nad Labem, Tsjekkia, 250 01
    - Medicus Services s.r.o.
  - Brandýs nad Labem, Tsjekkia, 25001
    - Interni ordinace s.r.o
  - Brno, Tsjekkia, 636 00
    - Vojenska nemocnice Brno
  - Brno, Tsjekkia, 65691
    - Fakultni nemocnice u sv. Anny v Brne
  - Broumov, Tsjekkia, 550 01
    - Edumed s.r.o.
  - Bílovec, Tsjekkia, 743 01
    - HUMANITAS spol. s r.o.
  - Chomutov, Tsjekkia, 430 02
    - Ordinace pro choroby srdce s.r.o.
  - Chrudim, Tsjekkia, 537 01
    - MUDr. Jan Hubac s.r.o.
  - Jablonec nad Nisou, Tsjekkia, 46601
    - Kardiologie KarMa s.r.o
  - Kroměříž, Tsjekkia, 767 01
    - Lunacor s.r.o. - Ambulance kardiologie Centrum pro choroby srdce a cev
  - Litovel, Tsjekkia, 78401
    - Kardio Interna s.r.o.
  - Olomouc, Tsjekkia, 77900
    - Fakultni Nemocnice Olomouc
  - Olomouc, Tsjekkia, 77900
    - PreventaMed, s.r.o.
  - Olomouc, Tsjekkia, 779 00
    - MUDr. Zdenek Vomacka kardiologie a interna s.r.o.
  - Ostrava Poruba, Tsjekkia, 708 52
    - Cerebrovaskularni poradna s.r.o.
  - Pardubice, Tsjekkia, 530 03
    - Pardubicka krajska nemocnice a s
  - Pilsen, Tsjekkia, 304 60
    - Fakultni Nemocnice Plzen
  - Prague, Tsjekkia, 100 34
    - Fakultni nemocnice Kralovske Vinohrady
  - Prague, Tsjekkia, 128 00
    - Vseobecna fakultni nemocnice v Praze
  - Prague, Tsjekkia, 150 06
    - Fakultni nemocnice v Motole
  - Prague, Tsjekkia, 158 00
    - MUDr. Eva Zídkova
  - Prague, Tsjekkia, 101 00
    - MUDr. Jan KVASNICKA CSc. Angiologie kardiologie a interna
  - Prague, Tsjekkia, 110 00
    - Nemocnice Na Františku
  - Prague, Tsjekkia, 16902
    - Ustredni vojenske nemocnice Praha
  - Příbram, Tsjekkia, 26101
    - Centrum klinickeho vyzkumu
  - Slaný, Tsjekkia, 274 01
    - Nemocnice Slany, interni oddeleni
  - Trutnov, Tsjekkia, 541 01
    - Interni ambulance
  - Uherské Hradiště, Tsjekkia, 68601
    - Interni ambulance Dr.Stanislav Zemek
  - Zlín, Tsjekkia, 760 01
    - Cardio Research s r o
  - České Budějovice, Tsjekkia, 37001
    - Nemocnice Ceske Budejovice a s
Tyrkia (Türkiye)
- - Afyonkarahisar, Tyrkia (Türkiye), 03200
    - Afyon Kocatepe University Medical Faculty
  - Ankara, Tyrkia (Türkiye), 06100
    - Turkiye Yuksek Ihtisas Training and Research Hospital
  - Antalya, Tyrkia (Türkiye), 07070
    - Akdeniz University Medical Faculty
  - Istanbul, Tyrkia (Türkiye), 34899
    - Marmara University Pendik Training Hospital
  - Izmir, Tyrkia (Türkiye), 35340
    - Dokuz Eylul University Medical Faculty
  - Kayseri, Tyrkia (Türkiye), 38039
    - Erciyes University Medical Faculty
  - Mersin, Tyrkia (Türkiye), 33020
    - Mersin University Medical Faculty
  - Mersin, Tyrkia (Türkiye), 33330
    - Mersin University Medical Faculty Hospital
  - Samsun, Tyrkia (Türkiye), 55139
    - Ondokuz Mayis University
Tyskland
- - Altenburg, Tyskland, 04600
    - Klinikum Altenburger Land GmbH
  - Bad Friedrichshall, Tyskland, 74177
    - Klinikum am Plattenwald
  - Bad Homburg, Tyskland, 61348
    - Kardiologische Praxis Dr. med. univ. Jungmair
  - Bad Oeynhausen, Tyskland, 32545
    - Ruhr Universitat Bochum Diabeteszentrum
  - Bamberg, Tyskland, 96049
    - Dres. Haas Kirschner Wagner
  - Berlin, Tyskland, 10249
    - Vivantes Klinikum im Friedrichshain
  - Berlin, Tyskland, 13509
    - Vivantes Humboldt Klinikum
  - Berlin, Tyskland, 12200
    - Charite Campus Benjamin Franklin
  - Berlin, Tyskland, 10559
    - Augentagesklinik Spreebogen Berlin GbR
  - Berlin, Tyskland, 10967
    - Vivantes Klinikum Am Urban, Abt. fur Kardiologie
  - Berlin, Tyskland, 12621
    - Vivantes Klinikum Hellersdorf
  - Beuel, Tyskland, 53225
    - GFO Kliniken Bonn, Betriebsstaette St. Marien
  - Bielefeld, Tyskland, 33604
    - Klinikum Bielefeld
  - Coburg, Tyskland, 96450
    - Regiomed Klinikum Coburg
  - Dachau, Tyskland, 85221
    - Medizinisches Versorgungszentrum (MVZ) Dachau
  - Deggingen, Tyskland, 73326
    - Gemeinschaftspraxis
  - Dessau, Tyskland, 06846
    - Praxis-Dr. Frank Menzel
  - Dresden, Tyskland, 01067
    - Städtisches Klinikum Dresden
  - Dresden, Tyskland, 01099
    - FAZ Dresden-Neustadt GbR
  - Dresden, Tyskland, 01277
    - Hausärztlich-Kardiologisches MVZ Am Felsenkeller GmbH
  - Elsterwerda, Tyskland, 04910
    - ZKS Südbrandenburg GMBH
  - Essen, Tyskland, 45355
    - Medizentrum Essen Borbeck
  - Essen, Tyskland, 45355
    - Studienzentrum
  - Essen, Tyskland, 45355
    - Gemeinschaftspraxis Dres. Hagemann und Breiderhoff
  - Frankfurt, Tyskland, 60596
    - ClinPhenomics GmbH Co KG Studienzentrum Frankfurt
  - Freiburg im Breisgau, Tyskland, 79106
    - Universitaetsklinikum Freiburg
  - Hamburg, Tyskland, 22763
    - Asklepios Klinik Altona
  - Hamburg, Tyskland, 22415
    - Praxis Dr. Cornelia Schiewe
  - Hamburg, Tyskland, 20099
    - ClinPhenomics GmbH Co KG Studienzentrum Hamburg
  - Hamburg, Tyskland, 20099
    - Medizinisches Versorgungszentrum Prof. Mathey, Prof. Schofer GmbH
  - Haßloch, Tyskland, 67454
    - Killat Dr. Holger Kardiologische Praxis
  - Kassel, Tyskland, 34121
    - Ambulantes Herzzentrum Kassel
  - Kiel, Tyskland, 24105
    - Universitaetsklinikum Schleswig Holstein Campus Kiel
  - Ludwigshafen, Tyskland, 67063
    - Klinikum Ludwigshafen
  - Mainz, Tyskland, 55131
    - Katholisches Klinikum Mainz; Innere Medizin I- Kardiologie
  - Mannheim, Tyskland, 68165
    - Praxis für Pneumologie und Allergologie
  - Neuwied, Tyskland, 56564
    - Marienhaus Klinikum
  - Nuremberg, Tyskland, 90402
    - GP Dr. Haggenmiller PD Dr. Michael Jeserich
  - Papenburg, Tyskland, 26871
    - Kardiologische Praxis Papenburg
  - Stuhr, Tyskland, 28816
    - Praxisgemeinschaft Stuhr-Brinkum
  - Tübingen, Tyskland, 72076
    - Universitaetsklinikum Tuebingen
  - Wermsdorf, Tyskland, 04779
    - Kardiologische Praxis
  - Witten, Tyskland, 58455
    - Forschungszentrum Ruhr
  - Worms, Tyskland, 67550
    - Stadtkrankenhaus Worms
  - Wuppertal, Tyskland, 42283
    - Helios Klinikum Wuppertal GmbH
Ungarn
- - Baja, Ungarn, 6500
    - Lausmed Egeszsegugyi es Szolg. Kft.
  - Balatonfüred, Ungarn, 8230
    - DRC Gyogyszervizsgalo Kozpont Kft
  - Budapest, Ungarn, 1036
    - Obudai Egeszsegugyi Centrum Kft
  - Budapest, Ungarn, 1088
    - Semmelweis Egyetem
  - Budapest, Ungarn, 1096
    - Gottsegen György Országos Kardiológiai Intézet
  - Budapest, Ungarn, 1023
    - Budai Irgalmasrendi Korhaz
  - Budapest, Ungarn, 1122
    - Semmelweis Egyetem Varosmajori Sziv- es Ergyogyaszati Klinika
  - Budapest, Ungarn, 1106
    - Bajcsy-Zsilinszky Korhaz es Rendelointezet
  - Budapest, Ungarn, 1051
    - Belvaros-Lipotvaros Egeszsegugyi Szolgalat
  - Budapest, Ungarn, 1085
    - Szt. Rokus Hosp
  - Budapest, Ungarn, 1132
    - Med-Tima Kft
  - Budapest, Ungarn, 1152
    - Uno Medical Trials Ltd.
  - Budapest, Ungarn, 1097
    - Del Pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet Szent Laszlo Telephely
  - Békéscsaba, Ungarn, 5600
    - Belgyogyaszati es Kardiologiai Maganrendelo
  - Debrecen, Ungarn, 4032
    - Debreceni Egyetem
  - Debrecen, Ungarn, 4025
    - Belinus Orvosi es Szamtech. Bt.
  - Debrecen, Ungarn, 4032
    - Debreceni Egyetem 1
  - Gyula, Ungarn, 5700
    - Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz
  - Gyöngyös, Ungarn, 3200
    - Bugat Pal Korhaz
  - Hatvan, Ungarn, 3000
    - BKS Research Kft
  - Hódmezővásárhely, Ungarn, 6800
    - Csongrád Megyei Egészségügyi Ellátó Központ Hódmezővásárhely
  - Kaposvár, Ungarn, 7400
    - Somogy Megyei Kaposi Mór Oktató Kórház
  - Kecskemét, Ungarn, 6000
    - Bacs-Kiskun Megyei Korhaz
  - Komárom, Ungarn, 2900
    - Selye Janos Korhaz es Rendelointezet
  - Miskolc, Ungarn, 3530
    - IPR Hungary Kft
  - Mosonmagyaróvár, Ungarn, 9200
    - Karolina Korhaz-Rendelointezet
  - Mosonmagyaróvár, Ungarn, 9200
    - TaNaMed Kft.
  - Nyíregyháza, Ungarn, H-4405
    - Borbanya Praxis Eu. Kft.
  - Orosháza, Ungarn, 5900
    - Dr. Nagy Laszlo Kardiologiai Maganrendeles
  - Pécs, Ungarn, 7623
    - COROMED-SMO Kft
  - Szeged, Ungarn, 6725
    - Szegedi Tudomanyegyetem
  - Szolnok, Ungarn, 5000
    - Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointez
  - Szombathely, Ungarn, 9700
    - Markusovszky Egyetemi Oktatokorhaz
  - Székesfehérvár, Ungarn, 8000
    - Vita Verum Medical Egeszsegugyi Szolgaltato Bt
  - Zalaegerszeg, Ungarn, 8900
    - Belvarosi Egeszseghaz Kft
  - Zalaegerszeg, Ungarn, 8900
    - Obudai Egeszsegugyi Centrum Kft 1

Deltakelseskriterier

Forskere ser etter personer som passer til en bestemt beskrivelse, kalt kvalifikasjonskriterier. Noen eksempler på disse kriteriene er en persons generelle helsetilstand eller tidligere behandlinger.

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

18 år og eldre (Voksen, Eldre voksen)

Tar imot friske frivillige

Nei

Beskrivelse

Inklusjonskriterier:

Minimumsalder på 18 år
Medisinsk stabil og egnet for kronisk antitrombotisk behandling
Atrieflimmer kvalifisert til å motta antikoagulasjon
Deltakeren må tilfredsstille en eller begge av følgende kategorier av risikofaktorer (a eller b): a) en eller flere av følgende risikofaktorer: i) alder mindre enn eller lik 75 år, ii) historie med et klinisk symptomatisk hjerneslag. b) to eller flere av følgende risikofaktorer: i) alder mellom 65 og 74 år, ii) hypertensjon, iii) diabetes mellitus, iv) aterosklerotisk vaskulær sykdom, v) hjertesvikt

Ekskluderingskriterier:

Hemodynamisk signifikant klaffesykdom som potensielt vil kreve kirurgisk klaffeutskifting under studien
Alle andre tilstander enn AF som krever kronisk antikoagulasjon

Studieplan

Denne delen gir detaljer om studieplanen, inkludert hvordan studien er utformet og hva studien måler.

Hvordan er studiet utformet?

Designdetaljer

Primært formål: Behandling
Tildeling: Randomisert
Intervensjonsmodell: Parallell tildeling
Masking: Dobbelt

Antall våpen

Våpen og intervensjoner

Deltakergruppe / Arm	Intervensjon / Behandling
Eksperimentell: Milvexian Deltakerne vil motta milvexian 100 milligram (mg) oralt, to ganger daglig og placebo som matcher apixaban fra dag 1 til og med slutten av behandlingen (EOT). Deltakere etter EOT-besøket kan ha et alternativ til å motta åpent apixaban i passende dose (5 mg eller 2,5 mg, to ganger daglig), som sponsoren gir en 30-dagers forsyning for.	Legemiddel: Milvexian Milvexian vil bli administrert oralt. Legemiddel: Placebo Milvexian matchende milvexian placebo vil bli administrert oralt.
Aktiv komparator: Apixaban Deltakerne vil motta en placebo som matcher milvexian og en kapsel som inneholder apixaban 5 mg eller 2,5 mg oralt, to ganger daglig. Deltakere etter EOT-besøket kan ha et alternativ til å motta åpent apixaban (5 mg eller 2,5 mg, to ganger daglig) i passende dose, som sponsoren gir en 30-dagers forsyning for.	Legemiddel: Apixaban Apixaban vil bli administrert oralt. Legemiddel: Apixaban Placebo Apixaban-matchende apixaban placebo vil bli administrert oralt.

Hva måler studien?

Primære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Tid til den første forekomsten av sammensatt endepunkt av hjerneslag og systemisk emboli i ikke-sentralnervesystemet (CNS) Tidsramme: Inntil 4 år	Tiden til den første forekomsten av sammensatt endepunkt for slag og ikke-CNS systemisk emboli vil bli rapportert.	Inntil 4 år

Sekundære resultatmål

Resultatmål	Tiltaksbeskrivelse	Tidsramme
Tid til den første forekomsten av International Society of Thrombosis and Hemostasis (ISTH) store blødninger Tidsramme: Inntil 4 år	Tiden til den første forekomsten av ISTH større blødning vil bli rapportert.	Inntil 4 år
Tid til den første forekomsten av sammensetningen av ISTH Major og Clinically Relevant Non-Major (CRNM) blødning Tidsramme: Inntil 4 år	Tiden til den første forekomsten av sammensetningen av ISTH major- og CRNM-blødninger vil bli rapportert.	Inntil 4 år
Tid til den første forekomsten av sammensatt endepunkt av kardiovaskulær (CV) død, hjerteinfarkt (MI), hjerneslag og ikke-CNS systemisk emboli Tidsramme: Inntil 4 år	Tiden til den første forekomsten av sammensatt endepunkt av CV-død, MI, hjerneslag og ikke-CNS systemisk emboli vil bli rapportert.	Inntil 4 år
Tid til CV-død Tidsramme: Inntil 4 år	Tid til CV-død vil bli rapportert.	Inntil 4 år
Tid til den første forekomsten av sammensatt endepunkt av dødsfall av alle årsaker, MI, hjerneslag og ikke-CNS systemisk emboli Tidsramme: Inntil 4 år	Tid til den første forekomsten av sammensatt endepunkt for død av alle årsaker, MI, hjerneslag og ikke-CNS systemisk emboli vil bli rapportert.	Inntil 4 år
Tid til den første forekomsten av sammensatt endepunkt av CV-død, MI, hjerneslag, akutt ekstremitetsiskemi (ALI) og akutt sykehusinnleggelse for vaskulær årsak til iskemisk natur Tidsramme: Inntil 4 år	Tid til den første forekomsten av sammensatt endepunkt av CV-død, MI, hjerneslag, ALI [enhver uventet revaskularisering eller amputasjon av iskemisk lem]), og akutt sykehusinnleggelse for vaskulær årsak av iskemisk natur (inkludert dyp venetrombose [DVT] og lungeemboli [ PE]) vil bli rapportert.	Inntil 4 år
Tid til første forekomst av sammensatt endepunkt av hjerneslag, ikke-CNS systemisk emboli og i stor blødning Tidsramme: Opptil 4 år	Tid til den første forekomsten av sammensatt endepunkt for hjerneslag, vil ikke-CNS systemisk emboli og i stor blødning bli rapportert.	Opptil 4 år

Samarbeidspartnere og etterforskere

Det er her du vil finne personer og organisasjoner som er involvert i denne studien.

Sponsor

Janssen Research & Development, LLC

Samarbeidspartnere

Bristol-Myers Squibb

Etterforskere

Studieleder: Janssen Research & Development, LLC Clinical Trial, Janssen Research & Development, LLC

Publikasjoner og nyttige lenker

Den som er ansvarlig for å legge inn informasjon om studien leverer frivillig disse publikasjonene. Disse kan handle om alt relatert til studiet.

Generelle publikasjoner

Jain SS, Mahaffey KW, Pieper KS, Shimizu W, Potpara T, Ruff CT, Kamel H, Lewis BS, Cornel JH, Kowey PR, Horrow J, Strony J, Plotnikov AN, Li D, Weng S, Donahue J, Gibson CM, Steg PG, Mehran R, Weitz JI, Johnston SC, Hankey GJ, Harrington RA, Lam CSP; LIBREXIA AF Trial Investigators and Committees. Milvexian vs apixaban for stroke prevention in atrial fibrillation: The LIBREXIA atrial fibrillation trial rationale and design. Am Heart J. 2024 Nov;277:145-158. doi: 10.1016/j.ahj.2024.08.011. Epub 2024 Aug 29.

Studierekorddatoer

Disse datoene sporer fremdriften for innsending av studieposter og sammendragsresultater til ClinicalTrials.gov. Studieposter og rapporterte resultater gjennomgås av National Library of Medicine (NLM) for å sikre at de oppfyller spesifikke kvalitetskontrollstandarder før de legges ut på det offentlige nettstedet.

Studer hoveddatoer

Studiestart (Faktiske)

11. april 2023

Primær fullføring (Antatt)

8. desember 2026

Studiet fullført (Antatt)

8. desember 2026

Datoer for studieregistrering

Først innsendt

24. februar 2023

Først innsendt som oppfylte QC-kriteriene

24. februar 2023

Først lagt ut (Faktiske)

7. mars 2023

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

28. august 2026

Siste oppdatering sendt inn som oppfylte QC-kriteriene

27. august 2026

Sist bekreftet

1. august 2026

Mer informasjon

Begreper knyttet til denne studien

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

CR109220
70033093AFL3002 (Annen identifikator: Janssen Research & Development, LLC)
2022-501419-15-00 (Registeridentifikator: EUCT number)

Plan for individuelle deltakerdata (IPD)

Planlegger du å dele individuelle deltakerdata (IPD)?

IPD-planbeskrivelse

Datadelingspolicyen til Janssen Pharmaceutical Companies of Johnson & Johnson er tilgjengelig på www.janssen.com/clinical-trials/transparency. Som nevnt på dette nettstedet, kan forespørsler om tilgang til studiedata sendes inn via Yale Open Data Access (YODA) prosjektnettsted på yoda.yale.edu

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

Studerer et amerikansk FDA-regulert enhetsprodukt

Nei

Denne informasjonen ble hentet direkte fra nettstedet clinicaltrials.gov uten noen endringer. Hvis du har noen forespørsler om å endre, fjerne eller oppdatere studiedetaljene dine, vennligst kontakt register@clinicaltrials.gov. Så snart en endring er implementert på clinicaltrials.gov, vil denne også bli oppdatert automatisk på nettstedet vårt. .

En studie av Milvexian versus Apixaban hos deltakere med atrieflimmer (LIBREXIA-AF)

En fase 3, randomisert, dobbeltblind, dobbel-dummy, parallell gruppe, aktivt kontrollert studie for å evaluere effektiviteten og sikkerheten til Milvexian, en oral faktor XIa-hemmer, versus apixaban hos deltakere med atrieflimmer

Studieoversikt

Status

Forhold

Intervensjon / Behandling

Studietype

Registrering (Faktiske)

Fase

Kontakter og plasseringer

Studiesteder

Deltakelseskriterier

Kvalifikasjonskriterier

Alder som er kvalifisert for studier

Tar imot friske frivillige

Beskrivelse

Studieplan

Hvordan er studiet utformet?

Designdetaljer

Antall våpen

Våpen og intervensjoner

Deltakergruppe / Arm

Intervensjon / Behandling

Hva måler studien?

Primære resultatmål

Resultatmål

Tiltaksbeskrivelse

Tidsramme

Sekundære resultatmål

Resultatmål

Tiltaksbeskrivelse

Tidsramme

Samarbeidspartnere og etterforskere

Sponsor

Samarbeidspartnere

Etterforskere

Publikasjoner og nyttige lenker

Generelle publikasjoner

Studierekorddatoer

Studer hoveddatoer

Studiestart (Faktiske)

Primær fullføring (Antatt)

Studiet fullført (Antatt)

Datoer for studieregistrering

Først innsendt

Først innsendt som oppfylte QC-kriteriene

Først lagt ut (Faktiske)

Oppdateringer av studieposter

Sist oppdatering lagt ut (Faktiske)

Siste oppdatering sendt inn som oppfylte QC-kriteriene

Sist bekreftet

Mer informasjon

Begreper knyttet til denne studien

Ytterligere relevante MeSH-vilkår

Andre studie-ID-numre

Plan for individuelle deltakerdata (IPD)

Planlegger du å dele individuelle deltakerdata (IPD)?

IPD-planbeskrivelse

Legemiddel- og utstyrsinformasjon, studiedokumenter

Studerer et amerikansk FDA-regulert medikamentprodukt

Studerer et amerikansk FDA-regulert enhetsprodukt