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Effects of Supplementation on Performance in Football Players (FOOTBALL-TCP)

21. maj 2026 opdateret af: Krzysztof Mizera

Effects of Combined Taurine, Caffeine, and Phosphatidylserine Supplementation on Physical and Cognitive Performance in Professional Male Football Players

This study investigated the effects of short-term supplementation with taurine, caffeine, and phosphatidylserine on physical and cognitive performance in professional male football players. Eighty-one players were randomly assigned to one of three groups: placebo, taurine plus caffeine, or taurine plus caffeine combined with phosphatidylserine. Supplementation was administered for 10 days, with a final dose taken 60 minutes before a standardized 105-minute football training session.

Primary and secondary outcomes included sprint performance, reaction time, GPS-derived locomotor variables, and technical and tactical performance indicators. The aim of the study was to evaluate whether combined multi-ingredient supplementation could improve performance and attenuate fatigue-related declines under match-like conditions.

Studieoversigt

Status

Afsluttet

Betingelser

Intervention / Behandling

Detaljeret beskrivelse

This randomized, placebo-controlled, single-blind study evaluated the effects of combined supplementation with taurine, caffeine, and phosphatidylserine on physical and cognitive performance in professional male football players.

Eighty-one participants aged 19-32 years were randomly assigned to one of three groups: placebo (lactose), taurine plus caffeine (1500 mg taurine + 200 mg caffeine), or taurine plus caffeine plus phosphatidylserine (1500 mg taurine + 150 mg caffeine + 300 mg phosphatidylserine daily for 10 days). All participants completed a 10-day supplementation period, followed by a standardized 105-minute football training session.

Outcome measures included sprint performance (30 m sprint time), reaction time (visual and auditory), GPS-derived variables (total distance, sprint activity, speed, accelerations, and decelerations), and technical and tactical performance indicators assessed by coaching staff and video analysis.

The study was conducted under controlled environmental conditions and in accordance with standardized training procedures. Data were analyzed using analysis of variance (ANOVA) with post hoc testing. The aim was to determine whether multi-ingredient supplementation could enhance performance and reduce fatigue-related declines in a football-specific setting.

Undersøgelsestype

Interventionel

Tilmelding (Faktiske)

81

Fase

  • Ikke anvendelig

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

  • Polen
    • Łódżkie
      • Lodz, Łódżkie, Polen, 94-020
        • ŁKS Łódź

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Voksen

Tager imod sunde frivillige

Ja

Beskrivelse

Inclusion Criteria:

  • Male professional football (soccer) players
  • Age 19-32 years
  • Currently participating in regular team training (4-5 sessions per week)
  • Medically cleared for participation in high-intensity physical activity
  • Provided written informed consent

Exclusion Criteria:

  • Current injury or musculoskeletal condition affecting performance
  • Chronic disease or medical condition
  • Use of medications that may affect physical or cognitive performance
  • Regular use of dietary supplements or caffeine prior to the study period
  • Smoking or alcohol consumption
  • Failure to comply with study procedures

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

  • Primært formål: Grundvidenskab
  • Tildeling: Randomiseret
  • Interventionel model: Parallel tildeling
  • Maskning: Dobbelt

Våben og indgreb

Deltagergruppe / Arm
Intervention / Behandling
Placebo komparator: Placebo
Participants received a placebo (lactose) daily for 10 days.
Andet: Placebo
Placebo (lactose) administered daily for 10 days
Eksperimentel: Taurine + Caffeine
Participants received taurine (1500 mg) and caffeine (200 mg) daily for 10 days.
Kosttilskud: Taurine and Caffeine
Taurine 1500 mg and caffeine 200 mg administered daily for 10 days
Eksperimentel: Taurine + Caffeine + PS
Participants received taurine (1500 mg), caffeine (150 mg), and phosphatidylserine (300 mg) daily for 10 days.
Kosttilskud: Taurine, Caffeine, and Phosphatidylserine
Taurine 1500 mg, caffeine 150 mg, and phosphatidylserine 300 mg administered daily for 10 days

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
30 m sprint time (seconds)
Tidsramme: Day 10 (final training session following supplementation)
Time to complete a 30 meter sprint under standardized conditions, expressed in seconds; calculated as the mean of valid trials.
Day 10 (final training session following supplementation)

Sekundære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Reaction time (visual and auditory)
Tidsramme: Day 10 (post-supplementation)
Visual and auditory reaction time measured using standardized computerized reaction time tests (e.g., validated software-based assessment tools), expressed as mean response time in seconds across valid trials.
Day 10 (post-supplementation)
Total distance (meters)
Tidsramme: Day 10 (during standardized training session)
Total distance covered during the standardized training session, measured using GPS tracking devices (e.g., 10 Hz GPS units), expressed in meters.
Day 10 (during standardized training session)
Running speed (m/s)
Tidsramme: Day 10 (during standardized training session)
Mean running speed during the standardized training session, measured using GPS tracking devices (e.g., 10 Hz GPS units), expressed in meters per second.
Day 10 (during standardized training session)
Sprint count (number)
Tidsramme: Day 10 (during standardized training session)
Total number of sprint efforts recorded during the standardized training session using GPS tracking devices.
Day 10 (during standardized training session)
High-speed running distance (meters)
Tidsramme: Day 10 (during standardized training session)
Distance covered at high-speed running thresholds during the standardized training session, measured using GPS tracking and expressed in meters.
Day 10 (during standardized training session)

Andre resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Sprint time decline (%)
Tidsramme: Day 10 (during final training session; comparison between first and second halves)
Percentage decline in 30 m sprint time between the first and second halves of the standardized training session, measured using electronic timing gates and expressed as percentage change.
Day 10 (during final training session; comparison between first and second halves)
Running speed decline (%)
Tidsramme: Day 10 (during final training session; comparison between first and second halves)
Percentage decline in running speed between the first and second halves of the standardized training session, measured using GPS tracking devices and expressed as percentage change.
Day 10 (during final training session; comparison between first and second halves)
Passing accuracy (%)
Tidsramme: Day 10 (during standardized training session)
Percentage of successful passes during the standardized training session, assessed using video-based performance analysis and expressed as a percentage.
Day 10 (during standardized training session)
Dribbling success (%)
Tidsramme: Day 10 (during standardized training session)
Percentage of successful dribbling attempts during the standardized training session, assessed using video-based performance analysis and expressed as a percentage.
Day 10 (during standardized training session)
Ball recoveries (number)
Tidsramme: Day 10 (during standardized training session)
Total number of ball recoveries performed during the standardized training session, assessed using video-based performance analysis and expressed as a count.
Day 10 (during standardized training session)
Tactical performance score (units)
Tidsramme: Day 10 (during standardized training session)
Coach-rated tactical performance during the standardized training session, including positioning, decision-making, and support play, assessed using a standardized rating scale and expressed in standardized score units.
Day 10 (during standardized training session)

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Sponsor

Krzysztof Mizera

Efterforskere

  • Ledende efterforsker: Krzysztof Maciej MIZERA, PhD, 1. Vizja University in Warsaw, Faculty of Medical Sciences and Health Sciences, 01-143 Warsaw, Poland

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

25. marts 2025

Primær færdiggørelse (Faktiske)

5. april 2025

Studieafslutning (Faktiske)

5. april 2025

Datoer for studieregistrering

Først indsendt

28. april 2026

Først indsendt, der opfyldte QC-kriterier

5. maj 2026

Først opslået (Faktiske)

12. maj 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

26. maj 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

21. maj 2026

Sidst verificeret

1. maj 2026

Mere information

Begreber relateret til denne undersøgelse

Nøgleord

Yderligere relevante MeSH-vilkår

Andre undersøgelses-id-numre

  • MIZERA-2025-FOOTBALL-RCT

Plan for individuelle deltagerdata (IPD)

Planlægger du at dele individuelle deltagerdata (IPD)?

INGEN

IPD-planbeskrivelse

Individual participant data will not be publicly available due to confidentiality restrictions related to professional athletes. Data may be available from the corresponding author upon reasonable request.

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