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Effects of Supplementation on Performance in Football Players (FOOTBALL-TCP)

21 mai 2026 mis à jour par: Krzysztof Mizera

Effects of Combined Taurine, Caffeine, and Phosphatidylserine Supplementation on Physical and Cognitive Performance in Professional Male Football Players

This study investigated the effects of short-term supplementation with taurine, caffeine, and phosphatidylserine on physical and cognitive performance in professional male football players. Eighty-one players were randomly assigned to one of three groups: placebo, taurine plus caffeine, or taurine plus caffeine combined with phosphatidylserine. Supplementation was administered for 10 days, with a final dose taken 60 minutes before a standardized 105-minute football training session.

Primary and secondary outcomes included sprint performance, reaction time, GPS-derived locomotor variables, and technical and tactical performance indicators. The aim of the study was to evaluate whether combined multi-ingredient supplementation could improve performance and attenuate fatigue-related declines under match-like conditions.

Aperçu de l'étude

Statut

Complété

Les conditions

Intervention / Traitement

Description détaillée

This randomized, placebo-controlled, single-blind study evaluated the effects of combined supplementation with taurine, caffeine, and phosphatidylserine on physical and cognitive performance in professional male football players.

Eighty-one participants aged 19-32 years were randomly assigned to one of three groups: placebo (lactose), taurine plus caffeine (1500 mg taurine + 200 mg caffeine), or taurine plus caffeine plus phosphatidylserine (1500 mg taurine + 150 mg caffeine + 300 mg phosphatidylserine daily for 10 days). All participants completed a 10-day supplementation period, followed by a standardized 105-minute football training session.

Outcome measures included sprint performance (30 m sprint time), reaction time (visual and auditory), GPS-derived variables (total distance, sprint activity, speed, accelerations, and decelerations), and technical and tactical performance indicators assessed by coaching staff and video analysis.

The study was conducted under controlled environmental conditions and in accordance with standardized training procedures. Data were analyzed using analysis of variance (ANOVA) with post hoc testing. The aim was to determine whether multi-ingredient supplementation could enhance performance and reduce fatigue-related declines in a football-specific setting.

Type d'étude

Interventionnel

Inscription (Réel)

81

Phase

  • N'est pas applicable

Contacts et emplacements

Cette section fournit les coordonnées de ceux qui mènent l'étude et des informations sur le lieu où cette étude est menée.

Lieux d'étude

  • Pologne
    • Łódżkie
      • Lodz, Łódżkie, Pologne, 94-020
        • ŁKS Łódź

Critères de participation

Les chercheurs recherchent des personnes qui correspondent à une certaine description, appelée critères d'éligibilité. Certains exemples de ces critères sont l'état de santé général d'une personne ou des traitements antérieurs.

Critère d'éligibilité

Âges éligibles pour étudier

  • Adulte

Accepte les volontaires sains

Oui

La description

Inclusion Criteria:

  • Male professional football (soccer) players
  • Age 19-32 years
  • Currently participating in regular team training (4-5 sessions per week)
  • Medically cleared for participation in high-intensity physical activity
  • Provided written informed consent

Exclusion Criteria:

  • Current injury or musculoskeletal condition affecting performance
  • Chronic disease or medical condition
  • Use of medications that may affect physical or cognitive performance
  • Regular use of dietary supplements or caffeine prior to the study period
  • Smoking or alcohol consumption
  • Failure to comply with study procedures

Plan d'étude

Cette section fournit des détails sur le plan d'étude, y compris la façon dont l'étude est conçue et ce que l'étude mesure.

Comment l'étude est-elle conçue ?

Détails de conception

  • Objectif principal: Science basique
  • Répartition: Randomisé
  • Modèle interventionnel: Affectation parallèle
  • Masquage: Double

Armes et Interventions

Groupe de participants / Bras
Intervention / Traitement
Comparateur placebo: Placebo
Participants received a placebo (lactose) daily for 10 days.
Autre: Placebo
Placebo (lactose) administered daily for 10 days
Expérimental: Taurine + Caffeine
Participants received taurine (1500 mg) and caffeine (200 mg) daily for 10 days.
Complément alimentaire: Taurine and Caffeine
Taurine 1500 mg and caffeine 200 mg administered daily for 10 days
Expérimental: Taurine + Caffeine + PS
Participants received taurine (1500 mg), caffeine (150 mg), and phosphatidylserine (300 mg) daily for 10 days.
Complément alimentaire: Taurine, Caffeine, and Phosphatidylserine
Taurine 1500 mg, caffeine 150 mg, and phosphatidylserine 300 mg administered daily for 10 days

Que mesure l'étude ?

Principaux critères de jugement

Mesure des résultats
Description de la mesure
Délai
30 m sprint time (seconds)
Délai: Day 10 (final training session following supplementation)
Time to complete a 30 meter sprint under standardized conditions, expressed in seconds; calculated as the mean of valid trials.
Day 10 (final training session following supplementation)

Mesures de résultats secondaires

Mesure des résultats
Description de la mesure
Délai
Reaction time (visual and auditory)
Délai: Day 10 (post-supplementation)
Visual and auditory reaction time measured using standardized computerized reaction time tests (e.g., validated software-based assessment tools), expressed as mean response time in seconds across valid trials.
Day 10 (post-supplementation)
Total distance (meters)
Délai: Day 10 (during standardized training session)
Total distance covered during the standardized training session, measured using GPS tracking devices (e.g., 10 Hz GPS units), expressed in meters.
Day 10 (during standardized training session)
Running speed (m/s)
Délai: Day 10 (during standardized training session)
Mean running speed during the standardized training session, measured using GPS tracking devices (e.g., 10 Hz GPS units), expressed in meters per second.
Day 10 (during standardized training session)
Sprint count (number)
Délai: Day 10 (during standardized training session)
Total number of sprint efforts recorded during the standardized training session using GPS tracking devices.
Day 10 (during standardized training session)
High-speed running distance (meters)
Délai: Day 10 (during standardized training session)
Distance covered at high-speed running thresholds during the standardized training session, measured using GPS tracking and expressed in meters.
Day 10 (during standardized training session)

Autres mesures de résultats

Mesure des résultats
Description de la mesure
Délai
Sprint time decline (%)
Délai: Day 10 (during final training session; comparison between first and second halves)
Percentage decline in 30 m sprint time between the first and second halves of the standardized training session, measured using electronic timing gates and expressed as percentage change.
Day 10 (during final training session; comparison between first and second halves)
Running speed decline (%)
Délai: Day 10 (during final training session; comparison between first and second halves)
Percentage decline in running speed between the first and second halves of the standardized training session, measured using GPS tracking devices and expressed as percentage change.
Day 10 (during final training session; comparison between first and second halves)
Passing accuracy (%)
Délai: Day 10 (during standardized training session)
Percentage of successful passes during the standardized training session, assessed using video-based performance analysis and expressed as a percentage.
Day 10 (during standardized training session)
Dribbling success (%)
Délai: Day 10 (during standardized training session)
Percentage of successful dribbling attempts during the standardized training session, assessed using video-based performance analysis and expressed as a percentage.
Day 10 (during standardized training session)
Ball recoveries (number)
Délai: Day 10 (during standardized training session)
Total number of ball recoveries performed during the standardized training session, assessed using video-based performance analysis and expressed as a count.
Day 10 (during standardized training session)
Tactical performance score (units)
Délai: Day 10 (during standardized training session)
Coach-rated tactical performance during the standardized training session, including positioning, decision-making, and support play, assessed using a standardized rating scale and expressed in standardized score units.
Day 10 (during standardized training session)

Collaborateurs et enquêteurs

C'est ici que vous trouverez les personnes et les organisations impliquées dans cette étude.

Parrainer

Krzysztof Mizera

Les enquêteurs

  • Chercheur principal: Krzysztof Maciej MIZERA, PhD, 1. Vizja University in Warsaw, Faculty of Medical Sciences and Health Sciences, 01-143 Warsaw, Poland

Dates d'enregistrement des études

Ces dates suivent la progression des dossiers d'étude et des soumissions de résultats sommaires à ClinicalTrials.gov. Les dossiers d'étude et les résultats rapportés sont examinés par la Bibliothèque nationale de médecine (NLM) pour s'assurer qu'ils répondent à des normes de contrôle de qualité spécifiques avant d'être publiés sur le site Web public.

Dates principales de l'étude

Début de l'étude (Réel)

25 mars 2025

Achèvement primaire (Réel)

5 avril 2025

Achèvement de l'étude (Réel)

5 avril 2025

Dates d'inscription aux études

Première soumission

28 avril 2026

Première soumission répondant aux critères de contrôle qualité

5 mai 2026

Première publication (Réel)

12 mai 2026

Mises à jour des dossiers d'étude

Dernière mise à jour publiée (Réel)

26 mai 2026

Dernière mise à jour soumise répondant aux critères de contrôle qualité

21 mai 2026

Dernière vérification

1 mai 2026

Plus d'information

Termes liés à cette étude

Mots clés

Termes MeSH pertinents supplémentaires

Autres numéros d'identification d'étude

  • MIZERA-2025-FOOTBALL-RCT

Plan pour les données individuelles des participants (IPD)

Prévoyez-vous de partager les données individuelles des participants (DPI) ?

NON

Description du régime IPD

Individual participant data will not be publicly available due to confidentiality restrictions related to professional athletes. Data may be available from the corresponding author upon reasonable request.

Informations sur les médicaments et les dispositifs, documents d'étude

Étudie un produit pharmaceutique réglementé par la FDA américaine

Non

Étudie un produit d'appareil réglementé par la FDA américaine

Non

Ces informations ont été extraites directement du site Web clinicaltrials.gov sans aucune modification. Si vous avez des demandes de modification, de suppression ou de mise à jour des détails de votre étude, veuillez contacter register@clinicaltrials.gov. Dès qu'un changement est mis en œuvre sur clinicaltrials.gov, il sera également mis à jour automatiquement sur notre site Web .

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