High-Amplitude Functional Exercises in Older Adults With Mild Cognitive Impairment
9. august 2026 opdateret af: Yunus Emre Tutuneken, Istinye University
Effects of Dual-Task-Based High-Amplitude Functional Exercises on Balance and Functional Mobility in Older Adults With Mild Cognitive Impairment
This study will investigate the effects of dual-task-based high-amplitude functional exercises on balance and functional mobility in older adults with mild cognitive impairment.
A total of 36 participants aged 65 years and older will be randomly assigned to either a high-amplitude functional exercise group or a traditional balance and mobility exercise group.
Both groups will participate in exercise sessions four times per week for four weeks, with each session lasting 60 minutes.
The effects of the exercise programs will be evaluated by assessing balance, functional mobility, dual-task performance, walking performance, fear of falling, and independence in daily activities before and after the intervention.
Studieoversigt
Status
Ikke rekrutterer endnu
Betingelser
Undersøgelsestype
Interventionel
Tilmelding (Anslået)
36
Fase
- Ikke anvendelig
Deltagelseskriterier
Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.
Berettigelseskriterier
Aldre berettiget til at studere
- Ældre voksen
Tager imod sunde frivillige
Ingen
Beskrivelse
Inclusion Criteria:
- Living independently/actively in a nursing home.
- Diagnosis of Mild Cognitive Impairment (MCI) based on a standardized screening test, with a Montreal Cognitive Assessment (MoCA) score of 18-25.
- Ability to walk independently for at least 10 meters without an assistive device or with only a cane/single-point support.
- Sufficient vision and hearing capacity to follow dual-task instructions and exercise directions, which may be corrected with glasses or hearing aids.
- Stable medical condition that does not prevent participation in the exercise program throughout the study.
Exclusion Criteria:
- Diagnosis of dementia or severe cognitive impairment based on cognitive screening (MoCA <17).
- Neurological conditions that primarily affect balance, such as Parkinson's disease, residual effects of stroke, multiple sclerosis, or cerebellar ataxia.
- Severe osteoarthritis, active inflammatory joint disease, or a history of major orthopedic surgery within the previous 6 months that could limit exercise performance.
- Uncontrolled hypertension, heart failure (NYHA Class III-IV), or cardiopulmonary instability causing symptoms during exercise.
- Advanced vestibular pathology or severe loss of proprioception in the lower extremities that could be the primary cause of balance impairment.
Studieplan
Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.
Hvordan er undersøgelsen tilrettelagt?
Design detaljer
- Primært formål: Behandling
- Tildeling: Randomiseret
- Interventionel model: Parallel tildeling
- Maskning: Enkelt
Våben og indgreb
Deltagergruppe / Arm |
Intervention / Behandling |
|---|---|
|
Eksperimentel: Dual-Task-Based High-Amplitude Functional Exercise
|
Participants will receive a dual-task-based high-amplitude functional exercise program consisting of high-amplitude functional movements combined with progressively challenging cognitive tasks.
The program will be administered 4 times per week for 4 weeks, for a total of 16 sessions, with each session lasting 60 minutes.
Exercise intensity will be prescribed as maximal effort, corresponding to 7-8/10 on the Borg Rating of Perceived Exertion Scale.
The program will include seated and standing functional exercises, large-amplitude stepping movements, dynamic movements, large-amplitude walking, functional task activities, and complex functional tasks.
|
|
Aktiv komparator: Traditional Balance and Mobility Exercise
|
Participants will receive a traditional balance and mobility exercise program administered 4 times per week for 4 weeks, for a total of 16 sessions, with each session lasting 60 minutes.
Exercise intensity will be moderate, corresponding to 4-5/10 on the Borg Rating of Perceived Exertion Scale.
The program will consist of motor tasks without cognitive dual-task components.
|
Hvad måler undersøgelsen?
Primære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Dual-Task Timed Up and Go Test
Tidsramme: Baseline to post-intervention (4 weeks)
|
The Dual-Task TUG will assess functional mobility under cognitive load by adding a cognitive task to the standard Timed Up and Go test.
Test performance will be recorded as the time required to complete the task.
|
Baseline to post-intervention (4 weeks)
|
|
Mini-BESTest
Tidsramme: Baseline to post-intervention (4 weeks)
|
The Mini-BESTest will be used to assess balance performance across anticipatory postural control, reactive postural control, sensory orientation, and dynamic gait.
The scale consists of 14 items scored from 0 to 2, with a maximum total score of 28.
Higher scores indicate better balance performance.
|
Baseline to post-intervention (4 weeks)
|
|
Five Times Sit-to-Stand Test
Tidsramme: Baseline to post-intervention (4 weeks)
|
The Five Times Sit-to-Stand Test will be used to assess lower-extremity muscle strength and functional capacity.
The time required to complete five full sit-to-stand repetitions will be recorded.
|
Baseline to post-intervention (4 weeks)
|
Sekundære resultatmål
Resultatmål |
Foranstaltningsbeskrivelse |
Tidsramme |
|---|---|---|
|
Timed Up and Go Test (TUG)
Tidsramme: Baseline to post-intervention (4 weeks)
|
The TUG will be used to assess functional mobility and dynamic balance.
|
Baseline to post-intervention (4 weeks)
|
|
Edinburgh Visual Gait Score
Tidsramme: Baseline to post-intervention (4 weeks)
|
The EVGS will be used to assess gait quality through observational analysis of gait kinematics across different anatomical segments.
|
Baseline to post-intervention (4 weeks)
|
|
Dual-Task Walking Speed
Tidsramme: Baseline to post-intervention (4 weeks)
|
Walking speed will be measured during a cognitive dual-task condition over a 10-meter walking course and recorded in meters per second.
|
Baseline to post-intervention (4 weeks)
|
|
Dual-Task Cost
Tidsramme: Baseline to post-intervention (4 weeks)
|
Dual-task cost will be calculated from the TUG performance using the formula.
|
Baseline to post-intervention (4 weeks)
|
|
Falls Efficacy Scale-International I
Tidsramme: Baseline to post-intervention (4 weeks)
|
The FES-I will be used to assess concerns about falling during daily activities.
Higher scores indicate greater fear of falling.
|
Baseline to post-intervention (4 weeks)
|
|
Barthel Index
Tidsramme: Baseline to post-intervention (4 weeks)
|
The Barthel Index will be used to assess independence in basic activities of daily living, including eating, bathing, dressing, and transfers.
Scores range from 0 to 100, with higher scores indicating greater independence.
|
Baseline to post-intervention (4 weeks)
|
|
Global Change Scale
Tidsramme: Post-intervention (4 weeks)
|
The Global Change Scale will be used to assess participants' perceived change following the intervention.
Participants will rate perceived change from -5 (much worse) to +5 (much better).
|
Post-intervention (4 weeks)
|
Samarbejdspartnere og efterforskere
Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.
Sponsor
Datoer for undersøgelser
Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.
Studer store datoer
Studiestart (Anslået)
20. august 2026
Primær færdiggørelse (Anslået)
5. april 2027
Studieafslutning (Anslået)
5. april 2027
Datoer for studieregistrering
Først indsendt
9. august 2026
Først indsendt, der opfyldte QC-kriterier
9. august 2026
Først opslået (Faktiske)
13. august 2026
Opdateringer af undersøgelsesjournaler
Sidste opdatering sendt (Faktiske)
13. august 2026
Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier
9. august 2026
Sidst verificeret
1. august 2026
Mere information
Begreber relateret til denne undersøgelse
Nøgleord
Yderligere relevante MeSH-vilkår
Andre undersøgelses-id-numre
- 104
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